NBH RESEARCH FORUM SCHEDULE OF EVENTS

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1 NBH RESEARCH FORUM SCHEDULE OF EVENTS FRIDAY, JANUARY th 4:00 pm Registration: White Pine Lounge, Davis Center 4 Floor 4:0 pm Welcome and Introduction: Victor May, PhD, President, Vermont Chapter for the Society of Neuroscience; Livak Ballroom, Davis Center 4:30 pm Keynote Lecture: Ronald Emeson, PhD, Professor of Pharmacology, Molecular Physiology and Biophysics and Psychiatry, Vanderbilt University School of Medicine RNA Editing in Nervous System Function and Dysfunction Livak Ballroom, Davis Center th 5:30 pm Reception: White Pine Lounge, Davis Center 4 Floor SATURDAY, JANUARY 3 th 8:00 am Registration, Handy Room, Davis Center 4 Floor Light Breakfast - coffee/tea: White Pine Lounge nd Poster Setup, Mansfield Room, Davis Center Floor 8:30 am Introductory Remarks: Mark Bouton,, Director, Neuroscience, Behavior and Health Research Initiative, Livak Ballroom, Davis Center Platform Talks Session I Chairs: Marion Weir and Gregory Johnson Departments of Biology and Neuroscience Graduate Program, University of Vermont 8:40 am Dawei Li, PhD, Department of Microbiology and Molecular Genetics, UVM Viral DNA integration in the human genome and brain disease 9:00 am Estelle Spear, NGP, Department of Neurological Sciences, UVM Altered gastrointestinal motility in multiple sclerosis 9:0 am Chenyi Liao, Department of Chemistry, UVM Microsecond MD simulations to reveal dynamics and mechanisms of a Class B GPCR 9:40 am Megan Shipman, NGP, Department of Psychological Science, UVM Inactivation of the prelimbic cortex attenuates context-dependent excitatory operant responding

2 0:00 am S. Bradley King, Department of Psychological Science, UVM Chronic stress potentiates the response to intra-bnst PACAP infusion 0:0 am Coffee Break Session II Chairs: Roman Popov and Bradley King Neuroscience Graduate Program and Department of Psychological Science University of Vermont 0:40 am James Bishop, NGP, Department of Neurological Sciences, UVM Porcine Model to Define Pain Structural Neuroplasticity :00 am Riley St. Clair, NGP, Department of Biology, UVM Putting the [P] in [P]lexin: characterizing the phosphorylation of PlexinA by tyrosine kinase Fyn :0 am Arielle Baker, Department of Physiology and Neurobiology, Dartmouth Selective cholinergic modulation of layer 5 projection neurons in the mouse prefrontral cortex :40 am Max Mehlman, Department of Psychological & Brain Sciences, Dartmouth Functional and anatomical relationships between the dorsal striatum, medial precentral cortex and head direction circuit :00 pm Sydney Trask, Department of Psychological Science, UVM Learning to suppress behavior during operant extinction: implications for cue exposure therapy :0 pm Olivia Miles, Department of Psychological Science, UVM Intra-bed nucleus of the stria terminalis (BNST) pituitary adenylate cyclase activating polypeptide (PACAP) infusion reinstates cocaine seeking in rats :40 pm Lunch Break / Poster Viewing and Judging Mansfield Room, Davis Center :00 pm Awards and Closing

3 NEUROSCIENCE, BEHAVIOR AND HEALTH RESEARCH FORUM POSTER SESSION Poster Poster Poster 3 Poster 4 Poster 5 Poster 6 Poster 7 Regulation of Microtubule dynamics by Tau Rehan Ali and Christropher Berger Department of Molecular Physiology, University of Vermont College of Medicine, Burlington, VT Temporal coordination of hippocampal place cells reflects cognitive outcome post febrile status epilepticus Jeremy Barry Medicine, Burlington, Vermont Optogentic manipulation of hippocampal theta rhythm can obstruct performance in the active avoidance task Benjamin Blumberg, eremy Barry, Sean Flynn and Gregory L. Holmes Parabrachial PACAP activation of amygdala endosomal ERK signaling regulates the emotional component of pain Galen Missig, Linda Mei, Margaret A. Vizzard, James A. Waschek, 3 Sayamwong E. Hammack, Victor May and Karen M. Braas 3 Departments of Neurological Sciences and Psychological Science, University of Vermont College of, Department of Psychiatry and Behavioral Sciences, University of California Los Angeles, Los Angeles, CA PKM- is involved in cerebellar-dependent learning and memory Kutibh Chihabi, John T. Green and Anthony D. Morielli Departments of Psychological Science and Pharmacology,University of Vermont, Burlington, VT The COBRE Imaging and Physiology Core: Two New Confocal Setups Fully Operational Todd A. Clason, Cindy J. Forehand, and Rodney L. Parsons Department of Neurological Sciences, University of Vermont, College of Hypotensive actions of A noradrenergic neurons are abolished by increased BDNF expression in the PVN Nick C. Cruickshank, Chris L. Schaich, Zachary D. Einwag, Theresa L. Wellman and Benedek Erdos Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT 05405

4 Poster 8 Poster 9 Poster 0 Poster Poster Poster 3 Poster 4 Poster 5 Does the adaptive algorithm in the stop signal task introduce a confound in neuroimaging studies? Nicholas D Alberto, Bader Chaarani, Philip Spechler, Kelsey Hudson, Scott Mackay, Nick Allgaier, Matthew Albaugh, Catherine Orr, Mitchell Snowe, Robert Althoff, Alexandra Potter, Hugh Garavan, and the IMAGEN consortium. Department of Psychiatry, University of Vermont College of Medicine, Burlington, VT WNK- regulation of Kv.: A novel hypothesis for cognitive impairment in schizophrenia Adrian Dutkiewicz, MA; Anthony Morielli, PhD Neuroscience Graduate Program, Department of Pharmacology,University of Vermont College of The Role of the Plexin A Family in Eye Development. Emerson, S.E., Light, S.E., St. Clair, R.M., Ballif, B.A. and Ebert, A.M. Department of Biology, Neuroscience Graduate Program, University of Vermont, Burlington VT 05405,,, Contributions of pituitary adenylate cyclase-activating polypeptide (PACAP)/receptor signaling to increased voiding frequency and somatic sensitivity in mice with urothelium-specific overexpression (OE) of nerve growth factor (NGF) in the urinary bladder. Beatrice M. Girard, Susan Malley, Morgan E. Mathews, Margaret A. Vizzard The effect of cyclophosphamide on salt preference and detection threshold Michael Gomella, Evan Lowry, Ben Jewkes, Joy Benner, Eugene Delay Department of Biology, University of Vermont, Burlington, VT Mechanism(s) of transforming growth factor-beta (TGF- ) mediated bladder afferent nerve hyperexcitability E.J. Gonzalez, M.A. Vizzard Does axon initial segment plasticity regulate neuron excitability? Allan T. Gulledge and Jaime J. Bravo Department of Physiology and Neurobiology, Geisel School of Medicine, Thayer School of Engineering, Dartmouth College, Hanover, NH ACTH Prevents Deficits in Fear Extinction Associated with Early Life Seizures, 3,4 Andrew T. Massey, David K. Lerner, Gregory L. Holmes, Rod C. Scott, Amanda E. Hernan Medicine, Burlington, VT, USA 05405, University of Bath, Department of 3 Biological Sciences, Bath, UK, Dartmouth College, College of Arts and 4 Sciences, Hanover, NH, USA 03756, University College London, Institute of

5 Child Health, London WCN EH, UK Poster 6 Poster 7 Poster 8 Poster 9 Poster 0 Poster Characterization of mpfc layer 5/6 neurons following sub-anesthetic ketamine Gregory Johnson and Sayamwong Jom Hammack Department of Psychological ScienceUniversity of Vermont, Burlington, VT Preliminary QTL Mapping Suggests Candidate Regions for Ethanol- Induced Phenotypes in the Diversity Outbred Mouse Population 3 Steven Kasparek, Troy Wilcox, Dan Gatti, Eric Busch, Drew Kreuzman, 3 3 Benjamin Mansky, Sophie Masneuf, Erica Sagalyn, Kayvon Sharif, Dominik 3 Taterra, Walter Taylor, MaryThomas, Elissa J. Chesler, Andrew Holmes, and Clarissa C Parker Department of Psychology and Program in Neuroscience, Middlebury College, VT 05753, Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, 3 ME 04609, Laboratory of Behavioral and Genomic Neuroscience, NIAAA, NIH, Rockville MD 085 Identifying genes associated with conditioned fear in the Diversity Outbred mouse population using a forward genetic, genome-wide approach 3 Andrew Kreuzman, Troy Wilcox, Dan Gatti, Eric Busch, Steven Kasparek, 3 3 Drew Kreuzman, Benjamin Mansky, Sophie Masneuf, Erica Sagalyn, Kayvon Sharif, Dominik Taterra, Walter Taylor, Mary Thomas, Elissa J. Chesler, 3,4 Andrew Holmes, and Clarissa C. Parker Program in Neuroscience, Middlebury College, VT 05673, Center for Genome Dynamics, The Jackson Laboratory, Bar Harbor, ME 04609, 3Laboratory of Behavioral and Genomic Neuroscience, NIAAA, NIH, Rockville MD 085 4Department of Psychology, Middlebury College, VT Abundant 5-HT release from EC cells disrupts colonic motility Brigitte Lavoie, Dmitri Tchitchkan, Gary M. Mawe Kv. potassium channel role in Cerebellar learning and memory. S. C. Madasu, M. L. Shipman, J. T. Green, A. D. Morielli Departments of Pharmacology and Psychological Science, University of Vermont, Burlington, VT TRPV-mediated Ca+ Influx and Constriction of Middle Meningeal Arteries Inessa Manuelyan, Masayo Koide, Arsalan U. Syed, Bo Shui, Swapnil Sonkusare, Michael I. Kotlikoff, Mark T. Nelson and George C. Wellman Department of Pharmacology, University of Vermont College of Medicine, Burlington, VT, College of Veterinary Medicine Cornell University, Ithaca, NY

6 Poster Poster 3 Poster 4 Poster 5 Poster 6 Poster 7 Pituitary adenylate cyclase-activating polypeptide (PACAP) expression in lower urinary tract pathways (LUT) with cyclophosphamide (CYP)-induced cystitis in PACAP promoter-dependent EGFP BAC transgenic mice Morgan E. Mathews, Susan Malley, Beatrice M. Girard, Karen M. Braas, James A. Waschek, Victor May and Margaret A. Vizzard Dept. of Neurological Sciences, University of Vermont College of Medicine, Burlington, VT Dept. of Psychiatry and Behavioral Sciences, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA High resolution mapping of PACAP neurocircuits using a PACAP-EGFP transgenic mouse model.,3 4 5 Michael C. Condro, Anna Matynia, Nicholas N. Foster, Yukio Ago, Abha,3,3 K.Rajbhandari, Bhavaani Jayaram, Sachin Parikh, Eileen Nguyen, Victor 6 4 May, Hong-Wei Dong and James A. Waschek Department of Psychiatry and Psychology, Department of Ophthalmology, and 3 Brain Research Institute, University of California - Los Angeles, USA 90095; 4 Institute of Neuro Imaging and Informatics, University of Southern California, 5 Los Angeles, CA USA 90089, Laboratory of Medicinal Pharmacology, Osaka 6 University, Osaka, Japan; Department of Neurological Sciences, University of Vermont, USA Loss of mtor complex function impairs synaptic transmission and blocks the effects of Pten deletion. Matthew McCabe and Matthew Weston Sequential reprogramming and re-differentiation of reactive astrocytes to identify downstream targets of Jagged/Notch signaling in the peri-infarct area after stroke Matthew D. LeComte, Issei S. Shimada, Andrea L. Bibeau, and Jeffrey L. Spees Department of Medicine, University of Vermont College of Medicine, Burlington, VT Origin of Locally-Derived Neural Spheres from the Peri-Infarct Area Following Stroke Issei S. Shimada and Jeffrey L. Spees Department of Medicine, University of Vermont College of Medicine, Burlington, VT Minimally Complex Robotic Model of Human Step Initiation with Anticipatory Postural Adjustments, Roman E. Popov, Jesse V. Jacobs and Josh C. Bongard Departments of Rehabilitation and Motion Science, and Computer Science, University of Vermont, Burlington, VT 05405

7 Poster 8 Poster 9 Poster 30 Poster 3 Poster 3 Food-Seeking Inhibited While Hungry Can Renew in the Context of Satiation Scott T. Schepers and Mark E. Bouton Department of Psychological Science, University of Vermont Mechanisms of serotonergic A-receptor-mediated excitation in callosal projection neurons in the mouse prefrontal cortex Emily K. Stephens and Allan T. Gulledge Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, NH It s a HARS Knock Life for Fish: Characterizing Histidyl trna Synthetase in the Zebrafish Ashley Waldron, Susan Robey-Bond, Christopher Francklyn, and Alicia Ebert Department of Biology and Biochemistry, University of Vermont, Burlington, VT Disciplined self-observation of aphasic disturbances: recovery of a left hemisphere injured brain, and the insights learned from primary optic aphasia, and how my changed brain works now. Sarah Robinson Burlington, VT Renewal of extinguished behavior in the context of the preceding response Jeremey M. Trott, Eric A. Thrailkill and Mark E. Bouton Department of Psychological Science, University of Vermont, Burlington, VT 05405

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