Rationale for Decision Excluded Generic OTC equivalent available (Flonase Allergy Relief) Medicare status (if differs)

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1 BLUE SHIELD OF CALIFORNIA FIRST QUARTER 2015 FORMULARY AND MEDICATION POLICY UPDATES EFFECTIVE MARCH 19, 2015 The Blue Shield of California (BSC) Pharmacy and Therapeutics (P&T) Committee, consisting of network physicians and pharmacists, regularly evaluates drugs for formulary inclusion and medication policy coverage criteria. The First Quarter 2015 P&T Committee decisions on formulary changes, which apply to all members with an outpatient drug benefit, and medication policy changes are summarized below: PHARMACY BENEFIT FORMULARY UPDATE: Please refer to the appropriate drug formulary posted on our website for the following information available at blueshieldca.com drop down Members, select Pharmacy under Public Links, and select the appropriate drug formulary Standard Formulary, Plus Formulary or Medicare Formulary): Quantity limits, if applicable, for specific drugs Formulary status of newly available strengths of existing drugs. Note: The formulary status of newly available strengths of existing drugs will have the same formulary status as the existing strengths unless otherwise noted. Non-formulary or non-preferred and generic drugs that do not require prior authorization or step therapy Brand-name medications that are now non-formulary or non-preferred because these medications have newly available generic equivalents covered on the formulary For Medicare beneficiaries who are enrolled in an employer group Medicare Part D plan, the commercial formulary status applies unless otherwise stated. Note: Medicare = drugs excluded for Medicare Part D under the Social Security Act section 1927(d)(2); those that have not been approved by the FDA; and those that do not meet the definition of a Part D drug as described by the Social Security Act section 1927(k). DRUGS REMOVED FROM FORMULARY The following drug(s) were EXCLUDED from the Plus or Standard formulary, as noted: fluticasone nasal spray Rationale for Decision Excluded Generic OTC equivalent available (Flonase Allergy Relief) flunisolide, Nasonex DRUGS NOT ADDED to FORMULARY The following drugs were NOT added to the Plus or Standard Formulary as they do not have a clear advantage over formulary products. These drugs may have additional coverage restrictions as noted. Refer to member benefit summary for applicable member share of cost Indication Afrezza Diabetes (insulin) Humulin R, Humalog Blue Shield of California Page 1 of 5

2 Indication Belsomra Insomnia Step therapy Prior authorization if 65 years and >90 day limit Embeda Severe pain Evekeo Narcolepsy, ADHD Step therapy Glyxambi Type 2 diabetes Hysingla 20, 30, 40, 60mg Movantik Severe pain Opioid induced constipation generic sleep agents: Ambien, Ambien CR, Lunesta, Sonata morphine ER,transdermal fentanyl, oxycontin generic amphentamines; Adderall XR, Vyvanse 1 st line antidiabetic agent, then: Invokana, or Invokamet, and Januvia, or Janumet/ Janumet XR, and Nesina or Kazano or Oseni morphine ER, fentanyl transdermal, Oxycontin Amitiza (step therapy ) Obredon Cough Step therapy guaifenesin/ codeine Onexton Acne vulgaris Step therapy Rytary Parkinson s Step therapy Savaysa Atrial Fibrillation, DVT, PE (anticoagulant) Trezix Mod-severe pain Topical clindamycin/ benzoyl peroxide (Duac, Benzaclin) carbidopa/ levodopa CR (Sinemet CR) Eliquis, Xarelto ASA/ dihydrocodeine; APAP/ codeine Blue Shield of California Page 2 of 5

3 GENERICS WITH RESTRICTIONS The following drugs are newly available GENERIC drugs that were ADDED to the Plus or Standard Formularies with coverage restrictions (other new generic drugs are covered on formulary without restrictions): Newly available generic amlodipine/valsartan/hctz (brand name: Exforge HCT) Step therapy celecoxib (brand name: Celebrex) clobetasol propionate spray (brand name: Clobex spray) Step therapy Non formulary estradiol/norethindrone (generic Activella) estradiol transdermal patch (brand name: Vivelle-Dot) guanfacine (brand name: Intuniv) lamotrigine (brand name: Lamictal ODT) sulfacetamide sodium/sulfur (brand name: Plexion) tacrolimus (brand name: Protopic ointment) testosterone 1% gel (brand name: Androgel 1%) urea (brand name: Keralac cream) if age 65 if age 65 Step therapy Step therapy, 0.03%: if age >12 0.1%: if age <16 Step therapy DRUGS ADDED TO THE BLUE SHIELD SPECIALTY TIER The following drugs were ADDED to the Blue Shield Specialty Tier Refer to member benefit summary for applicable member share of cost. These drugs are obtained through the BSC specialty pharmacy network (excluding Medicare plans). Specialty Medicare Status Cosentyx Granix Hysingla 80, 100, 120mg Non Formulary Blue Shield of California Page 3 of 5

4 Specialty Medicare Status Ibrance Kitabis Pak Lenvima Lynparza Mircera Viekira Pak EXISTING DRUGS with NEW RESTRICTIONS The following drugs have no change in formulary status, but have NEW restrictions Current Status New Clobex Spray Non formulary Step therapy DRUGS ADDED TO FORMULARY The following drugs were ADDED to the Plus or Standard Formularies: Arnuity Ellipta Asmanex HFA Non preferred brand Non preferred brand Renvela Myrbetriq NP Thyroid Step therapy if age 65 Non preferred brand, Step therapy Non preferred brand, Prior authorization if age 65 MEDICAL BENEFIT MEDICATION POLICIES: The following coverage policies were created or updated and changes are effective on March 19, 2015 (unless stated otherwise) and available on the BSC Internet site, and Provider Portal: blueshieldca.com drop down Providers select Guidelines and Resources under Public Links Authorizations Clinical Policies and Guidelines Medication Policy Medication Policy List. Refer to medication policy for complete details. For description of change, refer to top of medication policy. Blincyto- New Botulinum toxins (Botox, Dysport, Myobloc, Xeomin) Updated Cosentyx - New Blue Shield of California Page 4 of 5

5 Cyramza - Updated Erbitux - Updated Granix Updated Hizentra Updated Invega Sustenna - Updated Keytruda Updated Lemtrada -- New Lucentis - Updated Mircera - New Neupogen - Updated Opdivo - New Rapivab New Rituxan Updated Somatuline Depot Updated Vectibix - Updated Xgeva - Updated For additional information, please call Blue Shield of California Page 5 of 5

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