588G: Dietary Antigen Testing: Sensitivity and Complement 1/5. Dietary Antigen Exposure by Food Group
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1 PATIENT NAME: CLINIC: DOB: SAMPLE DATE: RECEIVE DATE: REPORT DATE: R //2 /28/27 /29/27 /3/27 Dunwoody Labs 9 Dunwoody Park Suite 2 Dunwoody, GA 3338 USA Phone: Fax: Nine Dunwoody Park, Suite 2 Dunwoody, GA 3338 Phone: Fax: G: Dietary Antigen Testing: Sensitivity and Complement /5 Dietary Antigen Exposure by Food Group Meats, Dairy Poultry Meats, Dairy 5 Legumes, Beans Vegetables 4 Poultry 3 Fungi Fruits 2 Legumes, Beans Fish Shellfish Seeds, Nuts Fungi Herbs, Spices, Seasonings Grains, Grasses Grains, Grasses Fish Seeds, Nuts Fruits Herbs, Spices, Seasonings Shellfish Vegetables This test was developed and its performance characteristics determined by Dunwoody Labs or thirdparty reference affiliates. This test is not FDA approved, and FDA clearance is Page of 5 GA Clinical License: 446 CLIA ID: D29
2 R REPORT DATE: /3/27 588G: Dietary Antigen Testing: Sensitivity and Complement 2/ Dietary Antigen Exposure by Food Group High levels of IgG antibodies to milk antigens have been reported in patients with eczema and/or asthma. In a separate study high levels of IgG4 antibodies were detected in patients suffering from atopic dermatitis and/or bronchial asthma caused by hypersensitivity to soybean. In this report a human serum sample is probed for the presence of IgG s that have an exact affinity for specific dietary allergens. Dietary specific IgG s are clustered by food groups and the quantitative summation of the IgG s within the offending food group(s) are expressed graphically. The exclusion of the offending food group(s) from the diet has shown to improve the symptoms of these conditions.. Zar et al. Am J Gastroenterol 25; :5557 IgG Allergic reactions to dietary antigens can be immediate or delayed and the rate and types of reaction indicate different immune responses. Peter Gell and Robert Combs developed a system in 963 to classify these different reactions and this classification was later found to correlate with four different molecular pathways that lead to allergic responses. The four types were sensibly given the names Type I, II, III and IV hypersensitivity. There are four subclasses of the Gtype immunoglobulins produced in hypersensitivity reactions to dietary allergens and some of the subclasses of IgG are the most difficult to detect. In this report Type II/III responses are detected by measuring the IgG response to specific dietary antigens that mediates the production of food specific immune complexes. Complement IgG antibody levels can increase in the blood as a consequence of exposure to dietary antigens in the bloodstream, and elevated levels are seen in response to the most commonly eaten foods. These antibodies can combine with the specific dietary antigen to form a food immune complex. These complexes are thought to be the active agents for the delayed allergic responses. IgG mediated immune complexes are tagged for complement activity by complement antigens such as Cq and C3D. The absence or presence of complement activity is essential to the pathological pathway that the immune system follows in response to the offending dietary antigen or food group. This test was developed and its performance characteristics determined by Dunwoody Labs or thirdparty reference affiliates. This test is not FDA approved, and FDA clearance is not currently required for clinical use. Results are not intended to be used as the sole means for clinical diagnosis. Clinical correlation is required. Page 2 of 5 GA Clinical License: 446 CLIA ID: D29
3 R REPORT DATE: /3/27 588G: Dietary Antigen Testing: Sensitivity and Complement 3/ MEATS, DAIRY SHELLFISH Beef 5 ng/ml Clam 3 ng/ml Casein 95 ng/ml 243 Crab 7 ng/ml 32 2 Cow's Milk 388 ng/ml 29 Lobster 24 ng/ml Goat's Milk 3 ng/ml 253 Scallops 75 ng/ml Pork 5 ng/ml Shrimp 8 ng/ml 35 2 POULTRY FUNGI Chicken 8 ng/ml Aspergillus Mix 227 ng/ml 252 Egg Albumin 6 ng/ml 297 Brewer's Yeast 8 ng/ml Egg Yolk 82 ng/ml 74 Candida 949 ng/ml 52 Turkey 5 ng/ml Mushroom 23 ng/ml FISH LEGUMES, BEANS Codfish 275 ng/ml Green Pea 8 24 ng/ml Flounder 3 ng/ml 2 Kidney/Pinto 48 ng/ml 4 Halibut ng/ml Navy Bean 63 ng/ml Salmon 4 ng/ml Peanut 95 ng/ml Tuna 9 ng/ml Soybean 52 ng/ml This test was developed and its performance characteristics determined by Dunwoody Labs or thirdparty reference affiliates. This test is not FDA approved, and FDA clearance is Page 3 of 5 GA Clinical License: 446 CLIA ID: D29
4 R REPORT DATE: /3/27 588G: Dietary Antigen Testing: Sensitivity and Complement 4/ FRUITS FRUITS Apple 255 ng/ml Peach 27 ng/ml Avocado 6 ng/ml Pear 225 ng/ml Banana 55 ng/ml Pineapple 58 ng/ml Blueberry 393 ng/ml 24 Plum 39 ng/ml 53 Cantaloupe 338 ng/ml Squash Mix 3 ng/ml Cherry 24 ng/ml 4 Strawberry 7 ng/ml Coconut 385 ng/ml 56 Tomato 6 ng/ml 5 Cucumber 22 ng/ml Watermelon 23 ng/ml Grapefruit 22 ng/ml GRAINS, GRASSES Grapes 75 ng/ml Barley 33 ng/ml Green Olive 37 ng/ml 33 Corn 35 ng/ml Green Pepper 225 ng/ml 7 Gluten 3 ng/ml Honeydew Melon 2 ng/ml Oat 25 ng/ml Lemon 9 ng/ml 8 Rice 35 ng/ml Lime 49 ng/ml Rye 46 ng/ml Orange 3 ng/ml 32 Whole Wheat 48 ng/ml This test was developed and its performance characteristics determined by Dunwoody Labs or thirdparty reference affiliates. This test is not FDA approved, and FDA clearance is Page 4 of 5 GA Clinical License: 446 CLIA ID: D29
5 R REPORT DATE: /3/27 588G: Dietary Antigen Testing: Sensitivity and Complement 5/ VEGETABLES HERBS, SPICES, SEASONINGS Asparagus 36 ng/ml Dill Seed 44 ng/ml 6 Broccoli 342 ng/ml Garlic 34 ng/ml 46 Cabbage 2 ng/ml Mustard 35 ng/ml Carrot 346 ng/ml Oregano 6 ng/ml 29 Celery 29 ng/ml Peppermint 38 ng/ml Horseradish 45 ng/ml Vanilla 83 ng/ml Lettuce 45 ng/ml 4 2 SEEDS, NUTS Onion 2 ng/ml Almond 86 ng/ml Spinach 25 ng/ml Cacao 348 ng/ml Sweet Potato 23 ng/ml 22 Coffee 57 ng/ml 4 Tea 73 ng/ml 34 Cottonseed 2 ng/ml White Potato 25 ng/ml 9 English Walnut 625 ng/ml HERBS, SPICES, SEASONINGS Pecan 29 ng/ml 5 Basil 65 ng/ml 7 Sesame 62 ng/ml 5 Black Pepper 34 ng/ml 3 Sunflower Seed 7 ng/ml Cinnamon 77 ng/ml 95 This test was developed and its performance characteristics determined by Dunwoody Labs or thirdparty reference affiliates. This test is not FDA approved, and FDA clearance is Page 5 of 5 GA Clinical License: 446 CLIA ID: D29
588-Complete Dietary Antigen Testing
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