Stroke: Every Minute Counts! Primary Stroke Center, Ingalls Memorial Hospital

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1 Stroke: Every Minute Counts! Primary Stroke Center, Ingalls Memorial Hospital

2 Objectives Describe the A & P of the nervous system Outline pathophysiological changes in the nervous system that may alter the cerebral perfusion pressure. Describe the assessment of a patient with suspected CVA/TIA Describe the pathophysiology, signs/symptoms/management for patients with suspected CVA/TIA

3 External Brain Structures

4 The Cerebrum The largest portion of the brain is the cerebrum. It consists of two hemispheres that are connected together at the corpus callosum. The cerebrum is often divided into five lobes that are responsible for different brain functions. Corpus callosum

5 Lobes of the Cerebrum Limbic Lobe Frontal Lobe Parietal Lobe Temporal Lobe Occipital Lobe

6 Frontal Lobe The frontal lobe is the area of the brain responsible for higher cognitive functions. These include: Problem solving Spontaneity Memory Language Motivation Judgment Impulse control Social and sexual behavior.

7 Temporal Lobe The temporal lobe plays a role in emotions, and is also responsible for smelling, tasting, perception, memory, understanding music, aggressiveness, and sexual behavior. The temporal lobe also contains the language area of the brain.

8 Parietal Lobe The parietal lobe plays a role in our sensations of touch, smell, and taste. It also processes sensory and spatial awareness, and is a key component in eyehand co-ordination and arm movement. The parietal lobe also contains a specialized area called Wernicke s area that is responsible for matching written words with the sound of spoken speech.

9 Occipital Lobe The occipital lobe is at the rear of the brain and controls vision and recognition.

10 Limbic Lobe The limbic lobe is located deep in the brain, and makes up the limbic system. Functions include: Memory Emotion (fear, anger, pleasure)

11 Cerebellum The cerebellum is connected to the brainstem, and is the center for body movement and balance. Click image to play or pause video

12 Thalamus Thalamus means inner room in Greek, as it sits deep in the brain at the top of the brainstem. The thalamus is called the gateway to the cerebral cortex, as nearly all sensory inputs pass through it to the higher levels of the brain.

13 The Ventricles The ventricles are a complex series of spaces and tunnels through the center of the brain. The ventricles secrete cerebrospinal fluid, which suspends the brain in the skull. The ventricles also provide a route for chemical messengers that are widely distributed through the central nervous system. Click image to play or pause video

14 Cerebrospinal Fluid Cerebrospinal fluid is a colorless liquid that bathes the brain and spine. It is formed within the ventricles of the brain, and it circulates throughout the central nervous system. Cerebrospinal fluid fills the ventricles and meninges, allowing the brain to float within the skull. Click image to play or pause video

15 The Brainstem The brainstem is the most primitive part of the brain and controls the basic functions of life: breathing, heart rate, swallowing, reflexes to sight or sound, sweating, blood pressure, sleep, and balance. The brainstem can be divided into three major sections. Detailed brainstem anatomy. Click image to play or pause video

16 Autonomic Functions The brainstem controls the basic functions of life. Damage to these areas of the brain are usually fatal: The pons plays a critical role in respiration. The medulla oblongata is responsible for respiration and cardiovascular functions. Pons Medulla Oblongata

17 Brainstem Divisions Midbrain Pons Medulla Oblongata

18 The Medulla Oblongata The medulla oblongata merges seamlessly with the spinal cord and creates the base of the brainstem. The medulla is primarily a control center for vital involuntary reflexes such as swallowing, vomiting, sneezing, coughing, and regulation of cardiovascular and respiratory activity. The medulla is also the origin of many cranial nerves.

19 The Pons The pons is the rounded brainstem region between the midbrain and the medulla oblongata. In fact, pons means bridge in Latin. The main function of the pons is to connect the cerebellum to the rest of the brain and to modify the respiratory output of the medulla. The pons is the origin of several cranial nerves.

20 Brain Functions Vision Taste Cognition Emotion Speech Language Hearing Motor Cortex Sensory Cortex Autonomic Functions

21 Vision The visual cortex resides in the occipital lobe of the brain. Sensory impulses travel from the eyes via the optic nerve to the visual cortex. Damage to the visual cortex can result in blindness.

22 Taste The gustatory complex (green circle) is the part of the sensory cortex (purple area) that is responsible for taste.

23 Cognition The prefrontal cortex is involved with intellect, complex learning, and personality. Injuries to the front lobe can cause mental and personality changes.

24 Emotion Emotions are an extremely complex brain function. The emotional core of the brain is the limbic system. This is where senses and awareness are first processed in the brain. Mood and personality are mediated through the prefrontal cortex. This part of the brain is the center of higher cognitive and emotional functions. Prefrontal cortex Limbic system

25 Speech Broca s Area Broca s area is where we formulate speech and the area of the brain that sends motor instructions to the motor cortex. Injury to Broca s area can cause difficulty in speaking. The individual may know what words he or she wishes to speak, but will be unable to do so.

26 Language Wernicke s area is a specialized portion of the parietal lobe that recognizes and understands written and spoken language. Auditory Association Area Wernicke s area surrounds the auditory association area. Damage to this part of the brain can result in someone hearing speech, but not understanding it. Wernicke s Area

27 Hearing There are two auditory areas of the brain: The primary auditory area (brown circle) is what detects sounds that are transmitted from the ear. It is located in the sensory cortex. The auditory association area (purple circle) is the part of the brain that is used to recognize the sounds as speech, music, or noise.

28 Motor Cortex The motor portion of the cerebrum is illustrated here. The light red area is the premotor cortex, which is responsible for repetitive motions of learned motor skills. The dark red area is the primary motor area, and is responsible for control of skeletal muscles. Different areas of the brain are associated with different parts of the body. Injury to the motor cortex can result in motor disturbance in the associated body part.

29 Sensory Cortex The sensory portion of the cerebrum is illustrated here. Different areas of the brain are associated with different parts of the body, as can be seen below. Injury to the sensory cortex can result in sensory disturbance in the associated body part.

30 What you need to know about stroke: #1 cause of disability among adults in the US 795,000 American s each year suffer a stroke 40% are large vessel occlusion #5 cause of death among adults in the US 128,000 deaths per year from stroke Every 40 seconds someone has a stroke Sources: U.S. Centers for Disease Control and Prevention and the Heart Disease and Stroke Statistics Update, published by the American Heart Association.

31 What you need to know about stroke: (Continued) The risk for ischemic stroke in current smokers is about double that of nonsmokers Risk is five times higher for Atrial Fibrillation The average stroke patient loses 32,000 brain cells every second, 2 billion each minute 14% of those who have had a Stroke or TIA will have another within a year Sources: U.S. Centers for Disease Control and Prevention and the Heart Disease and Stroke Statistics Update, published by the American Heart Association.

32 What you need to know about stroke: (Continued) 25% of those who have had a Stroke will have another in 5 years 4 out of 5 families will somehow be affected by stroke over the course of a lifetime About 6.6 million Americans are Stroke Survivors Americans pay about $53.9 billion for strokerelated medical costs per year Sources: U.S. Centers for Disease Control and Prevention and the Heart Disease and Stroke Statistics Update, published by the American Heart Association.

33 What is a Stroke? A stroke occurs when blood flow to the brain is interrupted by a blocked or burst blood vessel.

34 Pathophysiology Blood flow to any part of the brain is impeded Deprivation of 1 minute can lead to recovery Longer periods produce microscopic necrosis of neurons Damage dependant on severity and duration of impeded blood flow Massive edema and Increased Intracranial Pressure or possibility of stroke extending

35 Stroke Warning Signs Sudden weakness or numbness of the face, arm or leg, especially on one side of the body Sudden confusion, trouble speaking or understanding Sudden trouble seeing in one or both eyes Sudden trouble walking, dizziness, loss of balance or coordination Sudden, severe headaches with no known cause

36 Transient Ischemic Attacks (TIAs) TIA s are warning strokes that can happen before a major stroke There is a 4% risk of stroke occurring within 48 hours of a TIA They occur when blood flow through a brain artery is blocked or reduced for a short time

37 Transient Ischemic Attacks (TIAs) TIA s usually last 10 minutes, but can last up to 24 hours. TIA symptoms are temporary but similar to those of a full-fledged stroke A person who has a TIA is 9.5 times more likely to have a stroke

38 What Are the Types of Stroke? Ischemic Stroke (Blockage) Caused when there is a blockage in the blood vessels to the brain Associated with valvular disease and A-Fib Hemorrhagic Stroke (Bleeding) Caused by burst or leaking blood vessels in the brain

39 Ischemic VS Hemorrhagic Stroke 87% are due to vascular obstruction or Ischemic (thrombi or emboli) 10% of all strokes are Intracerebral Hemorrhages (due to high blood pressure, aneurysm, AV Malfunction) 3% are due to Subarachnoid Hemorrhage Hemorrhagic strokes frequently have a sudden onset. Sources: U.S. Centers for Disease Control and Prevention and the Heart Disease and Stroke Statistics Update, published by the American Heart Association.

40 Hemorrhagic vs. Ischemic Stroke

41 Causes of Ischemic Stroke? Begins with the development of fatty deposits lining the blood vessel wall Thrombus: Development of blood clot at the fatty deposit Embolus: Traveling particle too large to pass through a small vessel

42 Causes of Hemorrhagic Stroke? Occurs when a weakened blood vessel ruptures Aneurysms: Ballooning of a weakened region of a blood vessel Arteriovenous Malformations (AVMs): Cluster of abnormal blood vessels

43 What Are the Effects of Stroke? Right Brain

44 What Are the Effects of Stroke? Left Brain

45 Risk Factors for Stroke Controllable Factors High BP High Cholesterol Diabetes Tobacco Use Alcohol Use Physical Inactivity Obesity Atherosclerosis Atrial Fibrillation Non-Controllable Factors Age Gender Race Family History Previous Stroke or TIA Fibromuscular Displaysia Hypercoagulable States

46 Public Awareness Public awareness campaigns put on by various organizations aim to highlight the importance of time and stroke symptom awareness F.A.S.T is a common tool used to help explain to the public the importance of time and stroke recognition in these situations Public awareness can help to save patients from long term disability and death. F.A.S.T F = Facial Droop A = Arm Drift S = Slurred Speech or No Speech T = Time is Important. Call 911

47 Time is Tissue: Emergency Cincinnati Stroke Scale Facial Droop (Have the patient show teeth or smile) Normal Both sides of face move equally well Abnormal One side of face doesn t move as well as the other. Arm Drift (Pt. closes eyes and holds both arms straight out for 10 seconds) Normal Both arms move the same or both arms do not move at all Abnormal One arm doesn t move or one arm drifts down compared with the other Speech (Have the patient say, you can t teach an old dog new tricks. Normal Pt. uses correct words with no slurring Abnormal Pt. slurs words, uses inappropriate words, or is unable to speak.

48 Suspected Stroke SMO Perform Cincinnati Stroke Scale Identify patients last known normal If Stroke scale positive, transport to the nearest most appropriate facility. Do not delay scene time. Initiate rapid transport. Check Blood glucose 12 lead EKG (if avail).

49 State of Illinois

50 Arriving on Time!

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