The Brain Conferences
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1 The Brain Conferences New Insights into Psychiatric Disorders through Computational, Biological and Developmental Approaches September 2016 Copenhagen, Denmark Sunday, 25 September :00-14:20 Arrival and registration 14:20-14:30 Welcome address from the Conference Chairs Session 1: Learning and Decision Making 14:30-15:30 15:30-16:00 16:00-16:30 Computational Psychiatry: The Missing Link Jonathan Cohen, Princeton Neuroscience Institute (USA) Encoding of action by dopamine and cortical neurons: implications for symptoms of psychiatric disorders? Bita Moghaddam, University of Pittsburgh (USA) Cognitive control over learning and action in corticostriatal circuits Michael J. Frank, Brown University (USA) 16:30-17:00 Coffee break 17:00-17:30 17:30-18:00 18:00-18:15 18:15-18:30 18:30-19:00 Corticostriatal mechanisms underlying individual differences in decision-making and addiction Stephanie Groman, Yale School of Medicine (USA) Normative Dysfunction: Why Bad Decisions Stay Bad Peter Dayan, University College London (United Kingdom) Perception of ambiguity: a bayesian approach with possible implications for psychosis Pantelis Leptourgos, École Normale Supérieure (France) A causal role for the anterior mid-cingulate cortex in negative affect and cognitive control Serenella Tolomeo, University of Dundee (United Kingdom) Michael Browning, University of Oxford (United Kingdom) 19:00-19:45 Welcome Drink & Snacks
2 09:00-10:00 10:30-10:45 10:45-11:00 Monday, 26 September 2016 Session 2: Affect and Mood Neural circuits important for valence processing Kay Tye, Massachusetts Institute of Technology (USA) Neurobiology of stress, depression, and antidepressants: remodelling synaptic connections Ronald S. Duman, Yale School of Medicine (USA) Neurobehavioral effects of cognitive-behavioural therapy on depression-related disruptions in reinforcement learning Vanessa Brown, Virginia Tech (USA) An improved technology supports the role the glutamatergic system in depression: a 7T MRS study Beata Godlewska, University of Oxford (United Kingdom) 11:00-11:30 Coffee Break and Group Picture 11:30-12:00 12:00-12:30 12:30-13:00 13:00-15:00 Lunch break 15:00-15:15 15:15-15:30 The mathematics of regulating emotions Quentin J.M. Huys, ETH Zürich & University of Zürich (Switzerland) Mood as momentum Yael Niv, Princeton University (USA) Targeting emotional bias in the treatment of depression Catherine J. Harmer, University of Oxford (United Kingdom) Session 3: Developmental Approaches Depletion of the Cytoplasmic Fragile X Mental Retardation Protein 1 leads to deficits in synaptic plasticity and autism-like behaviour Sarah Borrie, KU Leuven & VIB (Belgium) Neural activation patterns induced by chronic psychosocial stress in mice Mikaela Laine, University of Helsinki (Finland) 15:30-15:45 Poster Spotlights I (8 presentations, 90 seconds each) 15:45-17:45 Poster Session I & Afternoon Snack 17:45-18:15 Synapse-specification defects in models of autism-spectrum disorders Peter Scheiffele, Biozentrum, University of Basel (Switzerland) 18:15-18:45 18:45-19:15 Functional genomics of human brain development and implications for neurodevelopmental disorders Nenad Sestan, Yale School of Medicine (USA) Tiago Maia, University of Lisbon (Portugal) 19:30-21:30 Optional Dinner at Madklubben Bistro de Luxe 2
3 Tuesday, 27 September 2016 Session 4: Stress and Compulsion 09:00-10:00 Molecular mechanisms of gene x stress interactions: implications for psychiatric disorders Elisabeth Binder, Max Planck Institute of Psychiatry, Munich (Germany) Flexibility of threat learning in post-traumatic stress disorder Daniela Schiller, Icahn School of Medicine at Mount Sinai (USA) 10:30-11:00 Coffee Break 11:00-11:30 11:30-12:00 Cognitive dysfunction in depression and obsessive compulsive disorder (OCD) Barbara J. Sahakian, University of Cambridge (United Kingdom) The dimensionality of compulsivity Valerie Voon, University of Cambridge (United Kingdom) 12:00-14:15 Lunch Break 12:30-14:15 Guided city tour walk (for those who subscribe for the guided tour) Session 5: Schizophrenia 14:15-14:45 14:45-15:15 Mapping the Neural Circuitry Substrate for Cognitive Dysfunction in Schizophrenia David A. Lewis, University of Pittsburgh (USA) Cortical microcircuit dysfunction contributing to working memory impairment in schizophrenia: computational and experimental insights John H. Krystal, Yale School of Medicine (USA) 15:15-15:30 Poster Spotlights II (8 presentations, 90 seconds each) 15:30-17:30 Poster Session II + Afternoon Snack 17:30-18:00 18:00-18:30 18:30-19:00 From genes to cognition in a genetic mouse model of schizophrenia predisposition Joshua Gordon, Columbia University (USA) Oscillations and Neuronal Dynamics in Schizophrenia: The Search for Basic Symptoms and Translational Opportunities Peter Uhlhaas, University of Glasgow (United Kingdom) Sophie Denève, École Normale Supérieure (France) 19:00- Free time, individual dinner 3
4 Wednesday, 28 September 2016 Session 6: Big Data/Large Cohorts 09:00-10:00 Assessing Moderated Effects of Mobile Health Interventions on Behaviour Susan A. Murphy, University of Michigan (USA) Machine learning and neuroimaging in psychiatry: the potential and the challenges Janaina Moureao-Miranda, University College London (United Kingdom) 10:30-11:00 Coffee Break 11:00-11:30 Risk and resilience mechanisms for psychiatric disorders Andreas Meyer-Lindeberg, Central Institute of Mental Health, Mannheim (Germany) 11:30-11:45 11:45-12:00 12:00-14:00 Lunch break 14:00-14:30 14:30-15:00 15:00-16:00 18:30-19:00 Farewell Drink Gene networks, neuron types, and brain circuits underlying common psychiatric disorders Dennis Vitkup, Columbia University (USA) Functional Flexibility in the Structural Connectome Promotes Cognitive Flexibility John Medaglia, University of Pennsylvania (USA) Genetic evidence for synaptic dysfunction in schizophrenia and related disorders Michael J. Owen, Cardiff University (United Kingdom) Psychiatric disorders as diseases of network dynamics Daniel Durstewitz, Central Institute of Mental Health, Mannheim (Germany) Tying it all together (discussion) John Krystal, Oscar Marín, Yael Niv 19:00-22:00 Gala Dinner and Poster Awards 4
5 5
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