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1 : B : B. B. : 76.. ELISA B. 86/8 6/6 6/6 : B. B (P 0/05) (100> B ).. High-risk. B : 1 firozzadfatah@gmail.com ( ) ١

2 Postvaccination Hepatitis B Antibody titer on students of Ardebil College of Dentistry Abstract Dr. Firouz Zad Fattah 1, Dr. Mehrdad Blourian 2, Aazam Sadegh 3 Background and objectives: Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease. Thus, the present study focuses on postvaccination Hepatitis B Antibody titer of dental students in order to evaluate the efficacy of Hepatitis B vaccine and the associated factors. Method: descriptive observational study method was used, which included questionnaires and serologic tests. The questionnaires contained questions on personal specifications, according which as many as 76 individuals were qualified as the subjects of the study. Blood samples were taken from the subjects in order to run test on Hepatitis B by using ELISA test. Statistical analysis was done on the obtained data by using Chi-square test and Fisher s exact test. Finding and conclusion: according to the obtained results 6.6% of the students had a negative titer, while another 6.6% were in borderline situation; whereas 86.8% produced a positive titer. Furthermore, the results revealed that there was an insignificance difference between Hepatitis B Antibody titer values and variables such as gender and needlestick injuries (P 0/05); whereas, Hepatitis B Antibody titer was significantly different for pre-clinical and clinical students. So revaccination (booster shot) must be considered for the individuals with a negative Hepatitis B Antibody titer who are considered as high-risk group in the society. Keywords: titer, Hepatitis B Virus, vaccine, dental students 1.Assistant Professor, Endodontics Department, Ardebil University of Medical Sciences, Ardebil, Iran. (corresponding author) firozzadfatah@gmail.com. 2. Assistant Professor, Endodontics Department, College of Dentistry of Ardebil University of Medical Science, Ardebil, Iran. 3. Dental student, College of Dentistry of Ardebil University of Medical Science, Ardebil, Iran. ٢

3 :..(1).(2) G A 6 B. E D C B A (3) (4) B. B.(5).(6) B (2005) Techasathit.(7-8) anti-hbs 2/2 Pre-clinical. B.(9) clinical..(10). B. 6 3.(11) B.(12) B. B. ٣

4 . ). ( ) ( 10MIU/ml 5cc 80. (100 ) HB s Ag anti-hb s anti- ( Bio-RAD ) ELISA. anti-hb c anti-hb c HbsAg bias. HB s B anti-hb c. (P-value 0.05) : ( 26/3% 73/7%) /7. (%27/6) 21 (%72/4) /99. 86/8 6/6 6/6. (13) ( ) Barsah.(14) 95/2..(15) HB 1.(9 18) (2005) Techasathit (1384).(P 0/05) Barsah. B. (17) (16) Shin (15). B.(19 20) (2000) Bonni (1998) Mujeeb ٤

5 HB.1 P (MIU/ml) B Titer >100 ( ) 10 Titer 100 ( ) Titer< 10 () 0/325 %72/4 %50 %17/1 %5/3 %27/6 %23/7 %2/6 %1/3 0/029 %73/7 %64/5 %6/6 %2/6 %26/3 %9/2 %13/2 %3/9 0/162 %44/7 %28/9 %13/2 %2/6 %55/3 %44/7 %6/6 %3/9. B. B.. B.. B B H B HB. :. ٥

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