Paraprofessional Home Visiting to Improve Maternal and Child Outcomes in South Africa: A Randomised Trial Professor Mark Tomlinson

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1 Paraprofessional Home Visiting to Improve Maternal and Child Outcomes in South Africa: A Randomised Trial Professor Mark Tomlinson Department of Psychology, Stellenbosch University, South Africa and Visiting Professor, Department of Psychiatry and Mental Health, University of Cape Town The Road to Melbourne: Young children born into HIV affected families. New York, May 2013

2 A man in a hot air balloon looked down and saw a man walking in a field. He shouted: hey, you, where am I? He looked up and answered: You are in a hot air balloon suspended vertically about 200 feet above the ground with no visible means of descent. Oh, you must be a researcher. Yes, how did you know? You are full of technically correct information that is totally irrelevant to my current situation. Oh, and you must be a policy maker. Yes, how did you know? You do not know where you are; you do not know what to ask to find out what you need; and you are blaming other people for your current situation.

3 Framing thoughts Small scale efficacy/effectiveness versus large scaled up programmes Supervision and management Survival versus life course well-being (1000 days and the other 5840 days) Community health workers central

4

5 Research stages and standards (adapted from Olds et al, 2007; and Flay et al, 2005) Effectiveness trials - meet all the standards for efficacy trials, plus: Use of most rigorous research design possible Clear specification of sample Use of valid outcome measures Appropriate statistical methods Impact of practical public health value Impacts maintained at least 6 months after end of intervention Replication of program impact in at least two separate trials Efficacy trials (ideal conditions) Program operationalized in manuals, training, and technical support Theory of causal mechanisms Clear statement of who benefits Measures of intervention exposure, integrity, and implementation Real-world target population and sampling method given Practical value specified Clear statement of hypotheses, Two high-quality trials Effectiveness trials (reallife-conditions) Evidence must meet standards for effectiveness Evidence must be available that the intervention can be delivered with fidelity to the model tested Cost information must be available Intervention must be supported by monitoring and evaluation tools Dissemination research E V I D E N C E M O S T L Y A B S E N T Horizontal Integrated Comprehensive Task shifting At scale At least a district or province Ideally nationally Comprehensive integrated programming

6

7 Philani has been a community-based agency since 1979 in Cape Town

8 Dr Ingrid Le Roux (Philani, South Africa); Professor Mary Jane Rotheram- Borus (UCLA, USA); Professor Carol Worthman (Emory University, USA); Professor Mary O Connor (UCLA, USA); Ms. Kwanie Mbewu (Philani, South Africa); Dr Jessica Harwood (UCLA, USA).

9 Community health workers core to the Philani programme

10 Programme components Selection positive peer deviants Training Monitoring Ongoing feedback

11 Method Cluster randomized controlled trial Khayelitsha and Mfuleni One CHW per neighbourhood cluster Neighbourhoods households

12 Content and visits Content: HIV, PMTCT Nutrition Maternal and child health (including TB) Alcohol use Accessing child grant Maternal mental health Mother-infant relationship and infant communication Antenatal and postnatal visit variable number

13 Mobile phones Collect research data Essential supervisory tool Monitor place, time and content of intervention delivery Provide MM and their supervisor data on content, process and outcome

14 CHW visit scheduling

15

16 Randomization worked well Neighborhoods were highly similar Shebeens Size Density Water sources Formal / informal housing Rates of HIV

17 Mothers were highly similar across conditions Age Education Income Number of previous children Previous low birth weight HIV status Partnerships

18 Results - Baseline 29% HIV+ 25% Alcohol using 17% Low birth weight 30% Depressed mood

19

20 Demographics

21 Percent Adherence across the PMTCT cascade SC ControPIP PMTCT cascade percentages 100.0% Maternal ARV at birth * 83.2% 92.4% 92.4% + Infant ARV 80.4% 88.3% + 6-Week 90.0% 88.3% PCR Test 76.2% 85.4% 83.2% + PCR Results 72.7% 82.5% 80.0% 80.4% 76.2% + One Feeding Method, 6 months ** 33.6% 45.6% 70.0% 60.0% 85.4% 72.7% 82.5% SC Control PIP 50.0% 40.0% 30.0% 20.0% 10.0% 33.6% 45.6% 0.0% *p<.05, **p<.01 Maternal ARV at birth * + Infant ARV + 6-Week PCR Test + PCR Results + One Feeding Method, 6 months ** le Roux, I., Tomlinson, M., Mbewu, N., et al (2013). AIDS.

22 Feeding at 6 months

23 Maternal antenatal depression and infant health at 18 months 60.0% SC PIP Mothers Depressed Antenatally (EPDS>18): Infant Health At 18 Months 50.0% 49.2% SC PIP 40.0% 30.0% 28.6% 30.5% 20.0% 15.7% 10.0% 0.0% Child had cough last two weeks* Significant at the 10% level, adjusted for neighborhood clustering. Since birth child admitted to hospital* *Significant at the 5% level.

24 Discussion Modest, but significant differences, in each area addressed Small gains often become magnified over time. 1. Pregnancy and infancy are critical developmental phases with lifelong consequences. Verplanken and Wood (2006) easier to shift behaviour during life transitions. 2. Small changes that can become habits have substantial impact over time

25 Discussion In the context of a horizontally/diagonally integrated programme with potential to scale Generalist approach family wide impact Training, supervision and management Task shifting approach Tailored to most salient health risks

26 Acknowledgements The women and children who participated in the study Funders: Ilifa Labantwana National Institute of Alcoholism and Alcohol Abuse (USA) Mark Tomlinson supported by National Research Foundation (South Africa)

27 Enkosi. Dankie. Kiitos! Zikomo kwambiri! Asante sana, Ye dewaese pii! Merci beaucoup! cảm ơn bạn! Obligado! Cam on! Kea leboga, Siyabonga! спасибо

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