Latent TB Infection in the WHO European Region and recommendations on LTBI s M&E framework
|
|
- Johnathan Quinn
- 6 years ago
- Views:
Transcription
1 Latent TB Infection in the WHO European Region and recommendations on LTBI s M&E framework 18 th Wolfheze workshops / 15 th NTP managers meeting, 31 May 02 June 2017 Dr Andrei DADU Technical officer, Joint TB, HIV/AIDS and Hepatitis Programme
2 Why Do We Have Drug Resistance on raise? Inadequate treatment Incorrect regimen (lack of drugs or knowledge) Poor adherence Treatment failure / relapse with drug resistant TB Transmission of drug resistant TB It is far easier to prevent TB in those infected without disease than to treat a full blown case of drug resistant TB
3 Scale-up of programmatic management of LTBI is critical in order to end the global TB epidemic as stated in the WHO s End TB Strategy. LTBI management contributes to the End TB Strategy targets Incidence of TB, projections to 2050 Mitigation of risk e.g. HIV prevention/art or prevention of infection by vaccine or infection control have limited impact on the trajectory of drop in TB incidence and so is the case with treatment of active TB alone However identification and treatment of latent infection in combination with active TB treatment can potentially accelerates reduction in TB incidence and achieve the End TB Strategy target Dye C et al., Prospects for Tuberculosis Elimination. Ann Rev Public Health :271-86
4 WHO LTBI Guidelines GLOBAL TB PROGRAMME Guidelines on the management of latent tuberculosis infection (high and upper middle-income countries with TB incidence <100/100, 000) WHO guidelines Recommendations for investigating contacts of persons with infectious tuberculosis in low- and middle-income countries WHO guidelines Guidelines for intensified tuberculosis case-finding and isoniazid preventive therapy for people living with HIV in resource-constrained settings WHO guidelines 2011 (to be updated 2015)
5 Published: October 25, 2016 Revised LTBI estimates 1 MDR is found in each 4 TB in Europe L MDR-TB I *: All ages = 31 millions 0-14 years = 610 thousands 0-4 years = 260 thousands * Provisional estimates / unpublished
6 MDR-TB and their contacts Estimated of all new RR/MDR-TB emerging RR/MDR-TB 120,000 Contacts of 0-4 years old 260,000 Estimated RR/MDR in all notified TB 74,000 Detected RR/MDR cases among all TB notified cases 47, ,000 94,000 Modified from JA Seddon et al, Lancet 2012
7 Target countries for LTBI packages er/lower-middle income per/upper-middle income TB >=100 or lower/lower-middle income TB <100 and upper/upper-middle income TB Incidence>=100 or lower/lower-middle income TB incidence<100 and upper/upper-middle income
8 A snapshot of the WHO s key recommendations
9 PILAR 1> INTEGRATED, PATIENT CENTRED CARE AND PREVENTION E. LTBI PROGRAMMATIC MANAGEMENT AND VACCINATION AGAINST TB
10 LTBI in the TB Action Plan in EUR ) TB Action Plan in EUR ): MS to adopt and adapt their national policies to align with the most up-to-date WHO recommendations on diagnosis and treatment of latent TB infection for high-risk populations. MS to ensure that WHO policy recommendations on BCG vaccination for infants are implemented and BCG revaccination is discontinued. MS to ensure that people accessing harm-reduction services for drug misuse will be provided the option of TB preventive therapy.
11 LTBI treatment enrollment rate among PLHIV (%) 100% 90% 80% 70% 60% 50% 40% 30% 20% 70% 50% 40% 39% 33% 19% 14% 10% 9% 36% 36% 90% in 2015: 36% IPT coverage among those newly enrolled into HIV care vs. in % as a baseline 10% 3% 0% 0%
12 LTBI in Global TB data collection form (EUR section only) National policy is available but rarely implemented and not reported Country X, 2015 data Total pop. = 3 mln 0-4 years pop. = Contacts, estimates = Actually screened = unk LTBI eligible = unk IPT enrolment = unk
13 LTBI in Global TB data collection form (only for EUR) Conutry Y, 2015 data Total pop. = 4 mln 0-4 years pop. = No LTBI national policy 0-4 years contacts, est. = 4 600* * By A.Dadu based on Houben & Dodd 0-4 years screened = 514 (14%) 0-4 year LTBI eligible = year IPT enrolment = 136 (27%) National policy is available but rarely implemented PLHIV, IPT enrolment = 19%
14 National policy on systematic screening for LTBI TB incidence > 20/100k 36 countries responded 23 targeting risk groups not recommended 3 TB incidence < 20/100k 8 countries responded Community contacts Previous treatment for TB Military School children
15 Challenges: policy implementation and practices Low enrolment rate in to the LTBI treatment among PLHIV (the beginning of the countrywide implementation) LTBI management miss-practices at country level (screening/detection); High RR/MDR prevalence among TB cases in the EECA countries: 9 out of top 10 global high MDR-TB burden countries; Weak LTBI [surveillance] and [response monitoring] in countries and therefore poor data at regional level; Poor cascade analysis understanding contacts children (weak cascade analysis) Estimates/Projections modelling and Drugs forecasting HCW commitment/engagement due to high overload on tasks and responsibilities Country health system that prevent the LTBI rolleout Challenges in LTBI resources mobilization Refugees and other categories of migrants influx across the boarders;
16 TAG 2017 recommendations LTBI management Adapt and disseminate criteria for prioritization of at-risk population among those for whom systematic LTBI testing and treatment is recommended, in agreement with the 2014 WHO policy document; Create an implementation guide for contact tracing, screening and management of contacts. Evaluate the opportunity for recommending active search of the contacts (children to be prioritized); Analyse bottlenecks in implementation of LTBI testing and treatment among PLHIV and children under the age of 5 who are household contacts, and propose solutions; Develop a framework for recording and reporting of LTBI data that allows measurements of contact and LTBI indicators, using WHO guidance document on LTBI M&E with reference to both global and national core indicators; Develop a regional position paper/expert opinion document on the use of Interferon Gamma Release Assays (IGRA) in LTBI detection; Develop a regional position paper/expert opinion document on rifapentine-containing regimens and assist Member States and partners facilitate the registration of the drug with European Medicine Agency and/or country drug regulatory authorities ; Promote research and assessment on LTBI.
Programmatic management of latent TB infection: Global perspective and updates. Haileyesus Getahun, MD, MPH, PhD.
Programmatic management of latent TB infection: Global perspective and updates Haileyesus Getahun, MD, MPH, PhD. What is latent TB infection? A state of persistent immune response to stimulation by Mycobacterium
More informationProgrammatic management of LTBI : a two pronged approach for ending the TB epidemic. Haileyesus Getahun Global TB Programme WHO/HQ
Programmatic management of LTBI : a two pronged approach for ending the TB epidemic Haileyesus Getahun Global TB Programme WHO/HQ What is latent TB infection? A state of persistent immune response to stimulation
More informationTime to implement: WHO guidelines on TB Preventive Treatment
Time to implement: WHO guidelines on TB Preventive Treatment WHO End TB Strategy TARGETS: 90% reduction of deaths and 80% reduction in incidence by 2030 Early diagnosis Integrated, of TB including universal
More informationLatent tuberculosis infection
EXECUTIVE SUMMARY Latent tuberculosis infection Updated and consolidated guidelines for programmatic management Executive summary Latent tuberculosis infection (LTBI) is defined as a state of persistent
More informationIPT IMPLEMENTATION- SWAZILAND EXPERIENCE
IPT IMPLEMENTATION- SWAZILAND EXPERIENCE Gugu Mchunu-National TB/HIV coordinator Programmatic Management of Latent TB infection consultation meeting Seoul, Republic of Korea,27-28 APRIL,2016 TB Epidemiology
More informationTB/HIV in the WHO European Region Overview, Priorities & Response
TB/HIV in the WHO European Region Overview, Priorities & Response 16 th Core Group Meeting TB/HIV Working Group Stop TB Partnership Almaty, Kazakhstan May 2010 Martin Donoghoe Andrei Dadu, Smiljka de Lussigny
More informationLTBI monitoring and evaluation in the Netherlands
LTBI monitoring and evaluation in the Netherlands 17 th Wolfheze Workshops 2015, Den Haag Connie Erkens MD MPH Senior TB consultant Content presentation Epidemiology Target groups for programmatic LTBI
More informationChildhood TB and new TB drugs in the WHO European Region
Andrei Dadu Carl Cordonnier Maxim Dondiuk Childhood TB and new TB drugs in the WHO European Region Kigali, Rwanda, 09/10/ 2017 Dr Martin van den Boom, MD, MSc PH, WHO Regional Office for Europe, Joint
More informationTuberculosis: Opportunities and Challenges for Achieving HIV Epidemic Control
Tuberculosis: Opportunities and Challenges for Achieving HIV Epidemic Control Suvanand Sahu Deputy Executive Director Stop TB Partnership Secretariat Tuberculosis TB epidemic is declining very slowly We
More informationTUBERCULOSIS AND HIV/AIDS: A STRATEGY FOR THE CONTROL OF A DUAL EPIDEMIC IN THE WHO AFRICAN REGION. Report of the Regional Director.
30 August 2007 REGIONAL COMMITTEE FOR AFRICA ORIGINAL: ENGLISH Fifty-seventh session Brazzaville, Republic of Congo, 27 31 August Provisional agenda item 7.8 TUBERCULOSIS AND HIV/AIDS: A STRATEGY FOR THE
More informationMODULE SIX. Global TB Institutions and Policy Framework. Treatment Action Group TB/HIV Advocacy Toolkit
MODULE SIX Global TB Institutions and Policy Framework Treatment Action Group TB/HIV Advocacy Toolkit 1 Topics to be Covered Global TB policy and coordinating structures The Stop TB Strategy TB/HIV collaborative
More informationExpanding Latent Tuberculosis Infection Testing and Treatment to Accelerate Tuberculosis Elimination
IUATLD North American Region Conference February 24, 2017 Vancouver, BC Expanding Latent Tuberculosis Infection Testing and Treatment to Accelerate Tuberculosis Elimination Philip LoBue, MD National Center
More informationTB 2015 burden, challenges, response. Dr Mario RAVIGLIONE Director
TB 2015 burden, challenges, response Dr Mario RAVIGLIONE Director Addis Ababa, Ethiopia 11-13 November 2015 Overview TB basics TB burden & challenges Response: End TB Strategy DAY 1 What is TB? Definition
More informationPROGRESS ON IMPLEMENTATION OF THE 3Is IN SOUTH AFRICA. Yogan Pillay Deputy Director General Strategic Health Programmes South Africa
PROGRESS ON IMPLEMENTATION OF THE 3Is IN SOUTH AFRICA Yogan Pillay Deputy Director General Strategic Health Programmes South Africa South Africa Population: 49 320 500 Mil Province Population 2009 mid
More informationThe WHO END-TB Strategy
ENDING TB and MDR-TB The WHO END-TB Strategy Dr Mario RAVIGLIONE Director Joint GDI/GLI Partners Forum WHO Geneva, 27 April 2015 This talk will deal with TB Burden Progress, Challenges Way Forward Who
More informationTuberculosis prevention: An under prioritized YET critical intervention to reduce child tuberculosis morbidity and mortality
Tuberculosis prevention: An under prioritized YET critical intervention to reduce child tuberculosis morbidity and mortality Moorine Penninah Sekadde Childhood TB focal point, NTP Uganda Annual meeting
More informationUGANDA NATIONAL TUBERCULOSIS AND LEPROSY CONTROL PROGRAMME
MINISTRY OF HEALTH UGANDA TIOL TUBERCULOSIS AND LEPROSY CONTROL PROGRAMME Revised Strategic Plan 2015/16-2019/20 Monitoring and Evaluation Plan Narrative of the Operational, Budget and Technical Assistance
More informationProgrammatic latent tuberculosis control in the European Union and candidate countries - Draft conclusions
ECDC GUIDANCE Programmatic latent tuberculosis control in the European Union and candidate countries - Draft conclusions Gerard de Vries Dominik Zenner On behalf of the ad hoc scientific panel appointed
More informationIntensified TB case finding among PLHIV and vulnerable population Identifying contacts Gunta Kirvelaite
Intensified TB case finding among PLHIV and vulnerable population Identifying contacts Gunta Kirvelaite Riga East Clinical hospital, Centre for tuberculosis and lung diseases. Head of outpatient department.
More informationWHO Global Health Sector Strategies HIV; Viral Hepatitis; Sexually Transmitted Infections
Common structure Universal Health Coverage SDGs Cascade of services Vision, Goals and Targets Costed Actions WHO Global Health Sector Strategies 2016-2021 HIV; Viral Hepatitis; Sexually Transmitted Infections
More informationGlobal strategy on viral hepatitis and regional action plan: monitoring framework and 10 core indicators
Global strategy on viral hepatitis and regional action plan: monitoring framework and 10 core indicators Antons Mozalevskis WHO Regional Office for Europe EMCDDA DRID National Expert Meeting Lisbon, 6
More informationGuidance on Matching Funds: Tuberculosis Finding the Missing People with TB
February 2017 Guidance on Matching Funds: Tuberculosis Finding the Missing People with TB 1. Background TB is the leading cause of death by infectious disease, killing 1.8 million people in 2015. Each
More informationContact Follow-Up and Treatment of LTBI in Households of Infectious Cases in Pakistan
Contact Follow-Up and Treatment of LTBI in Households of Infectious Cases in Pakistan 17 th Annual Conference, The Union-North American Region, Vancouver, Canada. 28 February 2013 Farhana Amanullah Director
More informationFinding the missing TB cases
Finding the missing TB cases Optimizing strategies to enhance case detection in high HIV burden settings Dr Malgosia Grzemska Global TB Programme, WHO/HQ, Geneva SWITZERLAND Child and Adolescent TB Working
More informationState Of Tuberculosis Elimination in the United States, 2017
National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention State Of Tuberculosis Elimination in the United States, 2017 Philip LoBue, MD Director, Division of Tuberculosis Elimination Congressional
More informationSession-1: Template for country presentation (EXISTING Indicators)
Session-1: Template for country presentation (EXISTING Indicators) Instruction This presentation is expected to provide Country perspective on use of following Existing indicators among the top 10 indicators
More informationPrinciple of Tuberculosis Control. CHIANG Chen-Yuan MD, MPH, DrPhilos
Principle of Tuberculosis Control CHIANG Chen-Yuan MD, MPH, DrPhilos Estimated global tuberculosis burden 2015 an estimated 10.4 million incident cases of TB (range, 8.7 million 12.2 million) 142 cases
More informationMeasuring TB burden and access to TB services for people who inject drugs in the WHO European Region, 2010 and 2011
Measuring TB burden and access to TB services for people who inject drugs in the WHO European Region, 2010 and 2011 Annabel Baddeley Global TB Programme WHO, Geneva Outline of presentation Global and European
More informationWhat Is New in Combination TB Prevention? Lisa J. Nelson Treatment and Care (TAC) Team HIV Department WHO HQ
What Is New in Combination TB Prevention? Lisa J. Nelson Treatment and Care (TAC) Team HIV Department WHO HQ Outline Combination prevention for HIV Approaches to TB prevention Individual Household/key
More informationNguyen Van Hung (NTP, Viet Nam)
Technical Consultation Meeting on the Programmatic Management of Latent Tuberculosis Infection 31 August-1 September 2017, Seoul, Republic Korea Adopting new LTBI diagnostics at country level: perspective
More informationOverview of the WHO policy on TB Infection Control and practical aspects and implementation tools for effective IC measures in Health facilities
Overview of the WHO policy on TB Infection Control and practical aspects and implementation tools for effective IC measures in Health facilities Dr. M. Angélica Salomão Medical Officer DOTS Expansion &
More informationInvesting for Impact
Global Fund Strategic Framework: Investing for Impact M&E: Capturing data to improve services Workshop to Scale Up the Implementation of Collaborative TB/HIV Activities in Africa 10-11 April, 2013; Maputo,
More informationPrevention and control of hepatitis B and C in the European Region of WHO
Prevention and control of hepatitis B and C in the European Region of WHO Viral Hepatitis Prevention Board Dr Nedret Emiroglu WHO Regional Office for Europe Burden of viral hepatitis in the European Region
More informationCurrent status of implementation and monitoring and evaluation of collaborative TB/HIV activities. Avinash Kanchar
Current status of implementation and monitoring and evaluation of collaborative TB/HIV activities Avinash Kanchar Outline WHO guide to M&E of collaborative TB/HIV activities: 2015 Reporting status on Global
More informationWhat is new in WHO-guidelines relevant for childhood TB?
Photo: Riccardo Venturi What is new in WHO-guidelines relevant for childhood TB? Dr Malgosia Grzemska Coordinator, Technical Support, Stop TB Department World Health Organization, Geneva, Switzerland 12th
More informationTB EPIDEMIOLOGY: IMPACT ON CHILDREN. Anneke C. Hesseling Desmond Tutu TB Centre Department Paediatrics and Child Health Stellenbosch University
TB EPIDEMIOLOGY: IMPACT ON CHILDREN Anneke C. Hesseling Desmond Tutu TB Centre Department Paediatrics and Child Health Stellenbosch University Robert Koch 1843-1910 Discovered M. tuberculosis 1882 TB deaths
More informationIPT Policy Review South Africa. WHO TB/HIV Working Group meeting
IPT Policy Review South Africa WHO TB/HIV Working Group meeting Outline Background Policy Environment Policy and Guidelines TB/HIV Collaboration Policy development process BACKGROUND Population: 53 Million
More informationPLANNING INTEGRATED HIV SERVICES AT THE HEALTH CENTRE
CHAPTER 2 PLANNING INTEGRATED HIV SERVICES AT THE HEALTH CENTRE 2.1 INTRODUCTION Achieving quality integrated HIV services at your health centre is dependant on good planning and management. This chapter
More informationWhy can t we eliminate tuberculosis?
Why can t we eliminate tuberculosis? Neil W. Schluger, M.D. Professor of Medicine, Epidemiology and Environmental Health Sciences Columbia University Chief Scientific Officer World Lung Foundation Current
More informationGoal of this chapter. 6.1 Introduction Good practices for linkage to care General care for people living with HIV 84
Clinical guidelines across THE CONTINuUM OF CARE: LINKING PEOPLE DIAGNOSEd WiTH hiv infection to hiv care and treatment 06 6.1 Introduction 84 6.2 Good practices for linkage to care 84 6.3 General care
More informationThe Tip of the Iceberg: Addressing Latent Tuberculosis Infection to Accelerate Tuberculosis Elimination
Four Corners TB and HIV Conference November 3, 2015 Durango, CO The Tip of the Iceberg: Addressing Latent Tuberculosis Infection to Accelerate Tuberculosis Elimination Philip LoBue, MD National Center
More informationAnnex A: Impact, Outcome and Coverage Indicators (including Glossary of Terms)
IMPACT INDICATORS (INDICATORS PER GOAL) HIV/AIDS TUBERCULOSIS MALARIA Reduced HIV prevalence among sexually active population Reduced HIV prevalence in specific groups (sex workers, clients of sex workers,
More informationTB/HIV Project in the Philippines. Yumiko Yanase
TB/HIV Project in the Philippines Yumiko Yanase 1 TB situation in the Philippines Global rank: 9th Incidence (all): 296 Prevalence (all): 458 TB mortality (all): 49 New MDR-TB: 3.2% Case types notified
More informationMonitoring top 10 indicators. Philippe Glaziou September 2016
Monitoring top 10 indicators Philippe Glaziou September 2016 Global TB Report 2016 outline top-10 indicators 1. Introduction 2. The SDGs, End TB Strategy and a new era of global TB monitoring 3. TB disease
More informationLatent tuberculosis infection
Latent tuberculosis infection Updated and consolidated guidelines for programmatic management ANNEX 3 Values and preferences for the management of latent tuberculosis infection: survey of populations affected
More informationTUBERCULOSIS. Presented By: Public Health Madison & Dane County
TUBERCULOSIS Presented By: Public Health Madison & Dane County What is Tuberculosis? Tuberculosis, or TB, is a disease caused by a bacteria called Mycobacterium tuberculosis. The bacteria can attack any
More informationScreening and management of latent TB Infection Gerry Davies
Screening and management of latent TB Infection Gerry Davies Reader in Infection Pharmacology Institutes of Infection and Global Health & Translational Medicine HIV Scientific Meeting Liverpool 21st July
More information10/3/2017. Updates in Tuberculosis. Global Tuberculosis, WHO 2015 report. Objectives. Disclosures. I have nothing to disclose
Disclosures Updates in Tuberculosis I have nothing to disclose Chris Keh, MD Assistant Clinical Professor, Division of Infectious Diseases, UCSF TB Controller, TB Prevention and Control Program, Population
More informationThe United Nations flag outside the Secretariat building of the United Nations, New York City, United States of America
The United Nations flag outside the Secretariat building of the United Nations, New York City, United States of America Mike Segar / Reuters Executive Summary Context On 26 September 2018, the United Nations
More informationTRANSITIONING FROM DONOR SUPPORT FOR TB & HIV IN EUROPE
TRANSITIONING FROM DONOR SUPPORT FOR TB & HIV IN EUROPE BULGARIA: CONTRACTING NGOs FOR BETTER RESULTS 1 CONTEXT Bulgaria has been a member state of the European Union (EU) since 2007 and is currently classified
More informationTB Infection Control Policy. Scaling-up the implementation of collaborative TB/HIV activities in the Region of the
TB Infection Control Policy Scaling-up the implementation of collaborative TB/HIV activities in the Region of the Infection Control is aimed at minimizing the risk of TB transmission within populations
More informationSIXTY-SEVENTH WORLD HEALTH ASSEMBLY A67/13 Provisional agenda item March Hepatitis
SIXTY-SEVENTH WORLD HEALTH ASSEMBLY A67/13 Provisional agenda item 12.3 28 March 2014 Hepatitis Improving the health of patients with viral hepatitis Report by the Secretariat 1. The Executive Board at
More informationThe Western Pacific Region faces significant
COMBATING COMMUNICABLE DISEASES A medical technician draws blood for HIV screening in Manila. AFP elimination of mother-to-child transmission of HIV and congenital syphilis was piloted in Malaysia and
More informationWorld Health Organization HIV/TB Facts 2011
World Health Organization HIV/TB Facts 20 Note: The facts and figures of the HIV/TB Facts 20 are drawn from WHO HIV and TB surveillance data from 200 and 2009, as referenced below. Why is tuberculosis
More informationINTERNAL QUESTIONS AND ANSWERS DRAFT
WHO CONSOLIDATED GUIDELINES ON THE USE OF ANTIRETROVIRAL DRUGS FOR TREATING AND PREVENTING HIV INFECTION Background: INTERNAL QUESTIONS AND ANSWERS DRAFT At the end of 2012, 9.7 million people were receiving
More informationProgress on the targets of Millennium Development Goal 6 in central and eastern Europe and central Asia
Progress on the targets of Millennium Development Goal 6 in central and eastern Europe and central Asia 11 October 2011 Moscow, Russian Federation Zsuzsanna Jakab WHO Regional Director for Europe Millennium
More informationReport on WHO Policy Statements
Report on WHO Policy Statements Christopher Gilpin TB Diagnostics and Laboratory Strengthening Unit Secretariat, Global Laboratory Initiative Stop TB Department, WHO Geneva New Diagnostics Working Group
More informationTuberculosis Epidemiology
Tuberculosis Epidemiology TB CLINICAL INTENSIVE COURSE Curry International Tuberculosis Center October 18, 2017 Varsha Hampole, MPH Tuberculosis Control Branch California Department Of Public Health Outline
More informationAction plan for the health sector response to HIV in the WHO European Region DRAFT. istock//brauns
Action plan for the health sector response to HIV in the WHO European Region DRAFT istock//brauns Action plan for the health sector response to HIV in the WHO European Region DRAFT 5.4 This document remains
More informationVersion for the Silent Procedure 29 April Agenda item January Hepatitis
Version for the Silent Procedure 29 April 2014 134th session EB134.R18 Agenda item 10.5 25 January 2014 Hepatitis The Executive Board, Having considered the report on hepatitis, 1 RECOMMENDS to the Sixty-seventh
More informationGlobal, regional and national strategic planning for viral hepatitis prevention and control
Global, regional and national strategic planning for viral hepatitis prevention and control Dr Antons Mozalevskis WHO Regional Office for Europe VHPB Baltic Meeting 19 20 November 2015 Riga, Latvia Presentation
More informationGeneral Session VI - Lee Reichman April 21, 2017
Culture of Collaboration 2017 National TB Conference April 21, 2017 Atlanta, GA Lee B. Reichman, MD, MPH Professor of Medicine, Senior Advisor Rutgers NJMS Global TB Institute Newark, NJ Rutgers, The State
More informationLatent Tuberculosis Infection (LTBI) Questions and Answers for Health Care Providers
Latent Tuberculosis Infection (LTBI) Questions and Answers for Health Care Providers Who Should Be Screened for Latent Tuberculosis Infection (LTBI)?... 2 What tests are used to screen for LTBI?... 2 How
More informationThe New WHO guidelines on intensified TB case finding and Isoniazid preventive therapy and operational considerations
Workshop to accelerate the implementation of the Three Is for HIV/TB and earlier initiation of ART in Southern Africa, March 14-18, 2011, Johannesburg, South Africa. The New WHO guidelines on intensified
More informationEthiopia. Targeted Tuberculosis Case Finding Interventions in Six Mining Shafts in Remote Districts of Oromia Region in Ethiopia PROJECT CONTEXT
Technical BRIEF Photo Credit: Challenge TB Targeted Tuberculosis Case Finding Interventions in Six Mining Shafts in Remote Districts of Oromia Region in Ethiopia PROJECT CONTEXT Ethiopia is the second-most
More informationTurning the Tide Against HIV and Tuberculosis. Global Fund Investment Guidance for Eastern Europe and Central Asia
Turning the Tide Against HIV and Tuberculosis Global Fund Investment Guidance for Eastern Europe and Central Asia Acknowledgement In order to ensure that the views of a variety of stakeholders were represented
More informationUNGASS COUNTRY PROGRESS REPORT Republic of Armenia
UNGASS COUNTRY PROGRESS REPORT Republic of Armenia Reporting period: January 2006 December 2007 I. Status at a glance The Armenia UNGASS Country Progress Report was developed under the overall guidance
More informationScaling up collaborative TB/HIV activities: achievements, challenges, and opportunities in Viet Nam
Scaling up collaborative TB/HIV activities: achievements, challenges, and opportunities in Viet Nam 20 th International AIDS Conference, 20 July 2014, Melbourne, Australia Nguyen Hoang Long, MD, Ph.D.
More informationMonitoring latent tuberculosis infection diagnosis and management in the Netherlands
ERJ Express. Published on February 25, 2016 as doi: 10.1183/13993003.01397-2015 ORIGINAL ARTICLE IN PRESS CORRECTED PROOF Monitoring latent tuberculosis infection diagnosis and management in the Netherlands
More informationTB/HIV Monitoring & Advocacy Project Interview Tool
TB/HIV Monitoring & Advocacy Project Interview Tool This interview tool is based upon the Interim Policy on Collaborative TB/HIV Activities of the World Health Organization. 1 It is designed to help you
More informationQuestions and Answers Press conference - Press Centre Room 3 Wednesday 16 August 2006, 14.00hrs
Questions and Answers Press conference - Press Centre Room 3 Wednesday 16 August 2006, 14.00hrs What causes TB? TB is caused by the bacterium Mycobacterium tuberculosis. Although it can cause disease in
More informationPublic health dimension of the world drug problem
SEVENTIETH WORLD HEALTH ASSEMBLY A70/29 Provisional agenda item 15.3 27 March 2017 Public health dimension of the world drug problem Report by the Secretariat 1. The Executive Board at its 140th session
More informationContextual overview with reference to MDG Goal 6 and projection for Post-2015
Contextual overview with reference to MDG Goal 6 and projection for Post-2015 10th Partnership Annual Conference Side Event Combating HIV and TB through a joint regional action Helsinki, Finland November
More informationPeggy Leslie-Smith, RN
Peggy Leslie-Smith, RN EMPLOYEE HEALTH DIRECTOR - AVERA TRAINING CONTENT 1. South Dakota Regulations 2. Iowa Regulations 3. Minnesota Regulations 4. Interferon Gamma Release Assay (IGRA)Testing 1 SOUTH
More informationAntiretroviral therapy for adults and adolescents KEY MESSAGES. HIV/AIDS Department BACKGROUND
KEY MESSAGES New WHO Recommendations: Antiretroviral therapy for adults and adolescents The World Health Organization (WHO) is revising its guidelines on antiretroviral therapy (ART) for adults and adolescents.
More informationControlling TB in the era of HIV
Controlling TB in the era of HIV Christy Hanson, PhD, MPH TB Research Advisor Amy Bloom, MD TB/HIV Advisor TB Incidence rates highest in Africa Estimated new TB cases (all forms) per 100 000 population
More informationMDR, XDR and Untreatable Tuberculosis and Laboratory Perspectives. Martie van der Walt TUBERCULOSIS EPIDEMIOLOGY & INTERVENTION RESEARCH UNIT
TUBERCULOSIS EPIDEMIOLOGY & INTERVENTION RESEARCH UNIT MDR, XDR and Untreatable Tuberculosis and Laboratory Perspectives Martie van der Walt IOM Meeting 15-17 January 2013 introduction 1 min 150 words
More informationGuidelines for TB contact tracing in Pacific Island countries and territories
Guidelines for TB contact tracing in Pacific Island countries and territories Background Tuberculosis (TB) continues to be a public health issue of major significance around the world. The World Health
More informationHIV-1 Vaccine Development Clinical Trials and Public Health Benefits Chaiyos Kunanusont HIV/AIDS Adviser United Nations Population Fund
The 2 nd Advanced Vaccinology course (NVCO) DDC, Radisson Bangkok 15 17 June 2010 HIV-1 Vaccine Development Clinical Trials and Public Health Benefits Chaiyos Kunanusont HIV/AIDS Adviser United Nations
More informationViral Hepatitis. WHO Regional Office for Europe July 2013
Viral Hepatitis WHO Regional Office for Europe July 2013 What is Hepatitis? Hepatitis is a viral infection that causes inflammation of the liver There are five main types of viral hepatitis: A, B, C, D,
More informationCommunicable Disease Control Manual Chapter 4: Tuberculosis. Assessment and Follow-Up of TB Contacts
Provincial TB Services 655 West 12th Avenue Vancouver, BC V5Z 4R4 www.bccdc.ca Communicable Disease Control Manual Assessment and Follow-Up of TB July, 2018 Page 1 TABLE OF CONTENTS 8.0 ASSESSMENT AND
More information4/25/2012. The information on patterns of infection and disease can assist in: Assessing current and evolving trends in TB
Sindy M. Paul, MD, MPH, FACPM May 1, 2012 The information on patterns of infection and disease can assist in: Assessing current and evolving trends in TB morbidity, including resistance Identifying people
More informationScaling Up Treatment in Zimbabwe: The path to high coverage
Scaling Up Treatment in Zimbabwe: The path to high coverage IAS Conference Dr. Tsitsi Mutasa-Apollo ART Programme Coordinator, Zimbabwe 30 th June, 2013 Kuala Lumpur, Malaysia Outline Introduction Background
More informationMozambique Draft 3Is workplan
Mozambique Draft 3Is workplan Background Mozambique is ranking the 16 th among the 22 high TB burden countries. Estimated TB incidence of all forms 409 per 100 000 population/yr (OMS) Absolute notifications
More informationIsoniazid Preventive Therapy (IPT)
Isoniazid Preventive Therapy (IPT) Josefina Cadorna-Carlos, M.D. Professor of Pediatrics U E R M M M C Objectives 1. Define IPT. 2. Discuss the indications for IPT. 3. Present RCT s for IPT (6H vs 9H).
More informationCatalytic Framework to End AIDS, TB and Eliminate Malaria in Africa by 2030
Catalytic Framework to End AIDS, TB and Eliminate Malaria in Africa by 2030 Introduction The Catalytic Framework to End AIDS, TB and Eliminate Malaria in Africa by 2030 provides an overarching policy framework
More informationMeasuring progress in global tuberculosis control: WHO Policy and Recommendations DRAFT
Measuring progress in global tuberculosis control: WHO Policy and Recommendations DRAFT IMPORTANT NOTE: The main policies and recommendations are summarized on page 6 (synthesis of recommendations for
More informationMonitoring, Evaluation, and Reporting (MER) Guidance (v.2.3): TB and HIV
Monitoring, Evaluation, and Reporting (MER) Guidance (v.2.3): TB and HIV Sean Cavanaugh, Senior TB Technical Advisor Office of the U.S. Global AIDS Coordinator & Health Diplomacy August 2018 Video Outline
More informationINH Prophylaxis Therapy (IPT) should NOT be implemented for all HIV patients in the Asia Pacific
INH Prophylaxis Therapy (IPT) should NOT be implemented for all HIV patients in the Asia Pacific Thuy Le, MD DPhil Duke University School of Medicine, USA Oxford University Clinical Research Unit Hospital
More informationHIV/AIDS IN EASTERN EUROPE AND CENTRAL ASIA (EECA) Charles Ssonko HIV/TB/Hepatitis Adviser Medecins Sans Frontieres
HIV/AIDS IN EASTERN EUROPE AND CENTRAL ASIA (EECA) Charles Ssonko HIV/TB/Hepatitis Adviser Medecins Sans Frontieres Objectives The Epidemiology of HIV/AIDS in the EECA Region (Trends) o The Burden of HIV/AIDS
More informationChristian Gunneberg MO WHO The 14th Core Group Meeting of the TB/HIV Working Group November 11-12, 2008, Addis Ababa, Ethiopia
The revised TB/HIV indicators and update on the process of harmonization Christian Gunneberg MO WHO The 14th Core Group Meeting of the TB/HIV Working Group November 11-12, 2008, Addis Ababa, Ethiopia Monitoring
More informationInfections What is new and what is important?
Infections What is new and what is important? 2 What am I going to talk about? Imported infections Meningitis changes Flu vaccine issues TB NICE guidance changes 3 Imported infections - Zika Transmitted
More informationThe epidemiology of tuberculosis
The epidemiology of tuberculosis Tuberculosis Workshop Shanghai, 12-22 May 28 Philippe Glaziou World Health Organization Outline Epidemiology refresher Estimates of tuberculosis disease burden Notifications
More informationTB IN EMERGENCIES. Disease Control in Humanitarian Emergencies (DCE)
TB IN EMERGENCIES Department of Epidemic and Pandemic Alert and Response (EPR) Health Security and Environment Cluster (HSE) (Acknowledgements WHO Stop TB Programme WHO/STB) 1 Why TB? >33% of the global
More informationGlobally, it is well documented that certain
Surveillance Report Characteristics and treatment outcomes of tuberculosis cases by risk groups, Japan, 2007 2010 Kazuhiro Uchimura, a Jintana Ngamvithayapong-Yanai, a Lisa Kawatsu, a Akihiro Ohkado, a
More informationhiv/aids Programme Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants
hiv/aids Programme Programmatic update Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants EXECUTIVE SUMMARY April 2012 EXECUTIVE SUMMARY Recent developments
More informationModelling BCG vaccination in the UK: What is the impact of changing vaccination policy?
Modelling BCG vaccination in the UK: What is the impact of changing vaccination policy? Sam Abbott Supervisors: Hannah Christensen, Ellen Brooks-Pollock University of Bristol 1 1. Lambert, M. L., Hasker,
More informationA Mobile Health Intervention Utilizing Community Partnership to Improve Access to Latent Tuberculosis Infection Treatment
A Mobile Health Intervention Utilizing Community Partnership to Improve Access to Latent Tuberculosis Infection Treatment Cassandra Garcia, MSN, RN, FNP-BC Mobile Clinic Provider Texas Children s Mobile
More informationBotswana Advocacy paper on Resource Mobilisation for HIV and AIDS
Republic of Botswana Botswana Advocacy paper on Resource Mobilisation for HIV and AIDS Page 1 June 2012 1.0 Background HIV and AIDS remains one of the critical human development challenges in Botswana.
More informationThe role of ART and IPT in TB prevention: Latest updates
The role of ART and IPT in TB prevention: Latest updates Richard E. Chaisson, MD Center for Tuberculosis Research Johns Hopkins University Consortium to Respond Effectively To the AIDS-TB Epidemic (CREATE)
More information