Package leaflet: Information for the patient. Padviram 600 mg/200 mg/245 mg, filmomhulde tabletten Efavirenz/Emtricitabine/Tenofovir disoproxil

Size: px
Start display at page:

Download "Package leaflet: Information for the patient. Padviram 600 mg/200 mg/245 mg, filmomhulde tabletten Efavirenz/Emtricitabine/Tenofovir disoproxil"

Transcription

1 Package leaflet: Infrmatin fr the patient 600 mg/200 mg/245 mg, filmmhulde tabletten Efavirenz/Emtricitabine/Tenfvir disprxil Read all f this leaflet carefully befre yu start taking this medicine because it cntains imprtant infrmatin fr yu. - Keep this leaflet. Yu may need t read it again. - If yu have any further questins, ask yur dctr r pharmacist. - This medicine has been prescribed fr yu nly. D nt pass it n t thers. It may harm them, even if their signs f illness are the same as yurs. - If yu get any side effects, talk t yur dctr r pharmacist. This includes any pssible side effects nt listed in this leaflet. See sectin 4. What is in this leaflet: 1. What is and what it is used fr 2. What yu need t knw befre yu take 3. Hw t take 4. Pssible side effects 5. Hw t stre 6. Cntents f the pack and ther infrmatin 1. What is and what it is used fr cntains three active substances that are used t treat human immundeficiency virus (HIV) infectin: - Efavirenz is a nn-nucleside reverse transcriptase inhibitr (NNRTI) - Emtricitabine is a nucleside reverse transcriptase inhibitr (NRTI) - Tenfvir is a nucletide reverse transcriptase inhibitr (NtRTI) Each f these active substances, als knwn as antiretrviral medicines, wrk by interfering with an enzyme (reverse transcriptase) that is essential fr the virus t multiply. is a treatment fr Human Immundeficiency Virus (HIV) infectin in adults aged 18 years and ver wh have previusly been treated with ther antiretrviral medicines and have their HIV-1 infectin under cntrl fr at least three mnths. Patients must nt have experienced failure f a previus HIV therapy. 2. What yu need t knw befre yu take D nt take - if yu are allergic t efavirenz, emtricitabine, tenfvir, tenfvir disprxil r any f the ther ingredients f this medicine (listed in sectin 6). - if yu have severe liver disease. - if yu are currently taking any f the fllwing medicines: astemizle r terfenadine (used t treat hay fever r ther allergies) bepridil (used t treat heart disease) cisapride (used t treat heartburn) ergt alkalids (fr example, ergtamine, dihydrergtamine, ergnvine, and 1

2 methylergnvine) (used t treat migraines and cluster headaches) midazlam r triazlam (used t help yu sleep) pimzide (used t treat certain mental cnditins) St. Jhn s wrt (Hypericum perfratum) (a herbal preparatin used fr depressin and anxiety) vricnazle (used t treat fungal infectins) If yu are taking any f these medicines, tell yur dctr immediately. Taking these medicines with culd cause serius r life-threatening side effects r stp these medicines frm wrking prperly. Warnings and precautins Talk t yur dctr r pharmacist befre taking this medicine. - Yu can still pass n HIV when taking this medicine, althugh the risk is lwered by effective antiretrviral therapy. Discuss with yur dctr the precautins needed t avid infecting ther peple. This medicine is nt a cure fr HIV infectin. While taking this medicine yu may still develp infectins r ther illnesses assciated with HIV infectin. - Yu must remain under the care f yur dctr while taking this medicine. - Tell yur dctr: if yu are taking ther medicines that cntain efavirenz, emtricitabine, tenfvir disprxil, tenfvir alafenamide r lamivudine r adefvir dipivxil. This medicine shuld nt be taken with any f these medicines. if yu have r have had kidney disease, r if tests have shwn prblems with yur kidneys. This medicine is nt recmmended if yu have mderate t severe kidney disease. This medicine may affect yur kidneys. Befre starting treatment, yur dctr may rder bld tests t assess kidney functin. Yur dctr may als rder bld tests during treatment t mnitr yur kidneys. This medicine is nt usually taken with ther medicines that can damage yur kidneys (see Other medicines and ). If this is unavidable, yur dctr will mnitr yur kidney functin nce a week. if yu have a histry f mental illness, including depressin, r f substance r alchl abuse. Tell yur dctr immediately if yu feel depressed, have suicidal thughts r have strange thughts (see sectin 4, Pssible side effects). if yu have a histry f cnvulsins (fits r seizures) r if yu are being treated with anticnvulsant therapy such as carbamazepine, phenbarbital and phenytin. If yu are taking any f these medicines, yur dctr may need t check the level f anticnvulsant medicine in yur bld t ensure that it is nt affected while taking this medicine. Yur dctr may give yu a different anticnvulsant. if yu have a histry f liver disease, including chrnic active hepatitis. Patients with liver disease including chrnic hepatitis B r C, wh are treated with cmbinatin antiretrvirals, have a higher risk f severe and ptentially lifethreatening liver prblems. Yur dctr may cnduct bld tests in rder t 2

3 check hw well yur liver is wrking r may switch yu t anther medicine. If yu have severe liver disease, d nt take (see earlier in sectin 2, D nt take ). If yu have hepatitis B infectin, yur dctr will carefully cnsider the best treatment regimen fr yu. Tenfvir disprxil and emtricitabine, tw f the active substances in this medicine, shw sme activity against hepatitis B virus althugh emtricitabine is nt apprved fr the treatment f hepatitis B infectin. Symptms f yur hepatitis may becme wrse after discntinuatin f this medicine. Yur dctr may then cnduct bld tests at regular intervals in rder t check hw well yur liver is wrking (see sectin 3, If yu stp taking ). Independent f a histry f liver disease, yur dctr will cnsider regular bld tests t check hw yur liver is wrking. if yu are ver 65. Insufficient numbers f patients ver 65 years f age have been studied. If yu are ver 65 years f age and are prescribed this medicine, yur dctr will mnitr yu carefully. - Once yu start taking, lk ut fr: signs f dizziness, difficulty sleeping, drwsiness, difficulty cncentrating r abnrmal dreaming. These side effects may start in the first 1 r 2 days f treatment and usually g away after the first 2 t 4 weeks. any signs f skin rash. Rashes may be caused by this medicine. If yu see any signs f a severe rash with blistering r fever, stp taking and tell yur dctr at nce. If yu had a rash while taking anther NNRTI, yu may be at higher risk f getting a rash with this medicine. any signs f inflammatin r infectin. In sme patients with advanced HIV infectin (AIDS) and a histry f pprtunistic infectin, signs and symptms f inflammatin frm previus infectins may ccur sn after anti-hiv treatment is started. It is believed that these symptms are due t imprvement in the bdy s immune respnse, enabling the bdy t fight infectins that may have been present with n bvius symptms. If yu ntice any symptms f infectin, please tell yur dctr at nce. In additin t the pprtunistic infectins, autimmune disrders (a cnditin that ccurs when the immune system attacks healthy bdy tissue) may als ccur after yu start taking medicines fr the treatment f yur HIV infectin. Autimmune disrders may ccur many mnths after the start f treatment. If yu ntice any symptms f infectin r ther symptms such as muscle weakness, weakness beginning in the hands and feet and mving up twards the trunk f the bdy, palpitatins, tremr r hyperactivity, please infrm yur dctr immediately t seek necessary treatment. bne prblems. Sme patients taking cmbinatin antiretrviral therapy may develp a bne disease called stenecrsis (death f bne tissue caused by lss f bld supply t the bne). The length f cmbinatin antiretrviral therapy, crticsterid use, alchl cnsumptin, severe immunsuppressin, higher bdy mass index, amng thers, may be sme f the many risk factrs fr develping this disease. Signs f stenecrsis are jint stiffness, aches and pains (especially f the hip, knee and shulder) and difficulty in mvement. If yu ntice any f these symptms please infrm yur dctr. 3

4 Bne prblems (smetimes resulting in fractures) may als ccur due t damage t kidney tubule cells (see sectin 4, Pssible side effects). Children and adlescents - D nt give t children and adlescents under 18 years f age. The use f this medicine in children and adlescents has nt been studied. Other medicines and Yu must nt take with certain medicines. These are listed under D nt take, at the start f sectin 2. They include sme cmmn medicines and sme herbal preparatins (including St. Jhn s wrt) which can cause serius interactins. Tell yur dctr r pharmacist if yu are taking, have recently taken r might take any ther medicines. Als, this medicine shuld nt be taken with any ther medicines that cntain efavirenz (unless recmmended by yur dctr), emtricitabine, tenfvir disprxil, tenfvir alafenamide r lamivudine r adefvir dipivxil. Tell yur dctr if yu are taking ther medicines which may damage yur kidneys. Sme examples include: - aminglycsides, vancmycin (medicines fr bacterial infectins) - fscarnet, ganciclvir, cidfvir (medicines fr viral infectins) - amphtericin B, pentamidine (medicines fr fungal infectins) - interleukin-2 (t treat cancer) - nn-steridal anti-inflammatry drugs (NSAIDs, t relieve bne r muscle pains) may interact with ther medicines, including herbal preparatins such as Ginkg bilba extracts. As a result, the amunts f this medicine r ther medicines in yur bld may be affected. This may stp yur medicines frm wrking prperly, r may make any side effects wrse. In sme cases, yur dctr may need t adjust yur dse r check yur bld levels. It is imprtant t tell yur dctr r pharmacist if yu are taking any f the fllwing: - Medicines cntaining didansine (fr HIV infectin): Taking this medicine with ther antiviral medicines that cntain didansine can raise the levels f didansine in yur bld and may reduce CD4 cell cunts. Inflammatin f the pancreas and lactic acidsis (excess lactic acid in the bld), which smetimes caused death, have been reprted rarely when medicines cntaining tenfvir disprxil and didansine were taken tgether. Yur dctr will carefully cnsider whether t treat yu with medicines cntaining tenfvir and didansine. - Other medicines used fr HIV infectin: The fllwing prtease inhibitrs: darunavir, indinavir, lpinavir/ritnavir, ritnavir, r ritnavir bsted atazanavir r saquinavir. Yur dctr may cnsider giving yu an alternative medicine r changing the dse f the prtease inhibitrs. Als, tell yur dctr if yu are taking maravirc. - Medicines used t treat infectin with the hepatitis C virus: bceprevir, telaprevir, simeprevir, sfsbuvir/velpatasvir. - Medicines used t lwer bld fats (als called statins): Atrvastatin, pravastatin, simvastatin. This medicine can reduce the amunt f statins in yur bld. Yur dctr will check yur chlesterl levels and will cnsider changing the dse f yur statin, if needed. - Medicines used t treat cnvulsins/seizures (anticnvulsants): Carbamazepine, phenytin, phenbarbital. can reduce the amunt f the anticnvulsant in 4

5 yur bld. Carbamazepine can reduce the amunt f efavirenz, ne f the cmpnents f this medicine, in yur bld. Yur dctr may need t cnsider giving yu a different anticnvulsant. - Medicines used t treat bacterial infectins, including tuberculsis and AIDSrelated mycbacterium avium cmplex: Clarithrmycin, rifabutin, rifampicin. Yur dctr may need t cnsider changing yur dse r giving yu an alternative antibitic. In additin, yur dctr may cnsider giving yu an additinal dse f efavirenz t treat yur HIV infectin. - Medicines used t treat fungal infectins (antifungals): Itracnazle r psacnazle. This medicine can reduce the amunt f itracnazle r psacnazle in yur bld. Yur dctr may need t cnsider giving yu a different antifungal. - Medicines used t treat malaria: Atvaqune/prguanil r artemether/lumefantrine. This medicine may reduce the amunt f atvaqune/prguanil r artemether/lumefantrine in yur bld. - Hrmnal cntraceptive, such as birth cntrl pills, an injected cntraceptive (fr example, Dep-Prvera), r a cntraceptive implant (fr example, Implann): Yu must als use a reliable barrier methd f cntraceptin (see Pregnancy and breast-feeding). may make hrmnal cntraceptives less likely t wrk. Pregnancies have ccurred in wmen taking efavirenz, a cmpnent f this medicine, while using a cntraceptive implant, althugh it has nt been established that the efavirenz therapy caused the cntraceptive t fail. - Methadne, a medicine used t treat piate addictin, as yur dctr may need t change yur methadne dse. - Sertraline, a medicine used t treat depressin, as yur dctr may need t change yur dse f sertraline. - Buprpin, a medicine used t treat depressin r t help yu stp smking, as yur dctr may need t change yur dse f buprpin. - Diltiazem r similar medicines (called calcium channel blckers): When yu start taking this medicine, yur dctr may need t adjust yur dse f the calcium channel blcker. - Medicines used t prevent rgan transplant rejectin (als called immunsuppressants), such as cyclsprine, sirlimus r tacrlimus. When yu start r stp taking this medicine yur dctr will clsely mnitr yur plasma levels f the immunsuppressant and may need t adjust its dse. - Warfarin r acencumarl (medicines used t reduce cltting f the bld): Yur dctr may need t adjust yur dse f warfarin r acencumarl. - Ginkg bilba extracts (herbal preparatin). Pregnancy and breast-feeding If yu are pregnant r breast-feeding, think yu may be pregnant r are planning t have a baby, ask yur dctr r pharmacist fr advice befre taking this medicine. Wmen shuld nt get pregnant during treatment with and fr 12 weeks thereafter. Yur dctr may require yu t take a pregnancy test t ensure yu are nt pregnant befre starting treatment with this medicine. If yu culd get pregnant while receiving, yu need t use a reliable frm f barrier cntraceptin (fr example, a cndm) with ther methds f cntraceptin including ral (pill) r ther hrmnal cntraceptives (fr example, implants, injectin). Efavirenz, ne f the active cmpnents f this medicine, may remain in yur bld fr a time after therapy is stpped. Therefre, yu shuld cntinue t use cntraceptive measures, as abve, fr 12 weeks after yu stp taking this medicine. 5

6 Tell yur dctr immediately if yu are pregnant r intend t becme pregnant. If yu are pregnant, yu shuld take nly if yu and yur dctr decide it is clearly needed. Serius birth defects have been seen in unbrn animals and in the babies f wmen treated with efavirenz during pregnancy. Ask yur dctr r pharmacist fr advice befre taking any medicine. If yu have taken during yur pregnancy, yur dctr may request regular bld tests and ther diagnstic tests t mnitr the develpment f yur child. In children whse mthers tk NRTIs during pregnancy, the benefit frm the prtectin against HIV utweighed the risk f side effects. D nt breast-feed during treatment with. Bth HIV and the ingredients f this medicine may pass thrugh breast milk and cause serius harm t yur baby. Driving and using machines may cause dizziness, impaired cncentratin and drwsiness. If yu are affected, d nt drive and d nt use any tls r machines. 3. Hw t take Always take this medicine exactly as yur dctr r pharmacist has tld yu. Check with yur dctr r pharmacist if yu are nt sure. The recmmended dse is: One tablet taken each day by muth. shuld be taken n an empty stmach (cmmnly defined as 1 hur befre r 2 hurs after a meal) preferably at bedtime. This may make sme side effects (fr example, dizziness, drwsiness) less trublesme. Swallw the tablet whle with water. must be taken every day. If yur dctr decides t stp ne f the cmpnents f this medicine, yu may be given efavirenz, emtricitabine and/r tenfvir disprxil separately r with ther medicines fr the treatment f yur HIV infectin. If yu take mre than yu shuld If yu accidentally take t many tablets yu may be at increased risk f experiencing pssible side effects with this medicine (see sectin 4, Pssible side effects). Cntact yur dctr r nearest emergency department fr advice. Keep the tablet bttle with yu s that yu can easily describe what yu have taken. If yu frget t take It is imprtant nt t miss a dse f. If yu d miss a dse f within 12 hurs f when it is usually taken, take it as sn as yu can, and then take yur next dse at its regular time. 6

7 If it is almst time (less than 12 hurs) fr yur next dse anyway, d nt take the missed dse. Wait and take the next dse at the regular time. D nt take a duble dse t make up fr a frgtten tablet. If yu thrw up the tablet (within 1 hur after taking ), yu shuld take anther tablet. D nt wait until yur next dse is due. Yu d nt need t take anther tablet if yu were sick mre than 1 hur after taking the tablet. If yu stp taking Dn t stp taking withut talking t yur dctr. Stpping this medicine can seriusly affect yur respnse t future treatment. If this medicine is stpped, speak t yur dctr befre yu restart taking tablets. Yur dctr may cnsider giving yu the cmpnents f this medicine separately if yu are having prblems r need yur dse adjusted. When yur supply f starts t run lw, get mre frm yur dctr r pharmacist. This is very imprtant because the amunt f virus may start t increase if the medicine is stpped fr even a shrt time. The virus may then becme harder t treat. If yu have bth HIV infectin and hepatitis B, it is especially imprtant nt t stp yur treatment withut talking t yur dctr first. Sme patients have had bld tests r symptms indicating that their hepatitis has gt wrse after stpping emtricitabine r tenfvir disprxil (tw f the three cmpnents f this medicine). If this medicine is stpped yur dctr may recmmend that yu resume hepatitis B treatment. Yu may require bld tests t check hw yur liver is wrking fr 4 mnths after stpping treatment. In sme patients with advanced liver disease r cirrhsis, stpping treatment is nt recmmended as this may lead t wrsening f yur hepatitis, which may be life-threatening. Tell yur dctr immediately abut new r unusual symptms after yu stp treatment, particularly symptms yu assciate with hepatitis B infectin. If yu have any further questins n the use f this medicine, ask yur dctr r pharmacist. 4. Pssible side effects During HIV therapy there may be an increase in weight and in levels f bld lipids and glucse. This is partly linked t restred health and life style, and in the case f bld lipids smetimes t the HIV medicines themselves. Yur dctr will test fr these changes. Like all medicines, this medicine can cause side effects, althugh nt everybdy gets them. Pssible serius side effects: tell yur dctr immediately Lactic acidsis (excess lactic acid in the bld) is a rare (may affect up t 1 in 1,000 peple) but serius side effect that can be fatal. The fllwing side effects may be signs f lactic acidsis: deep rapid breathing drwsiness feeling sick (nausea), being sick (vmiting) and stmach pain. If yu think yu may have lactic acidsis, cntact yur dctr immediately. Other pssible serius side effects 7

8 The fllwing side effects are uncmmn (may affect up t 1 in every 100 peple): - allergic reactin (hypersensitivity) that may cause severe skin reactins (Stevens- Jhnsn syndrme, erythema multifrme, see sectin 2) - swelling f the face, lips, tngue r thrat - angry behaviur, suicidal thughts, strange thughts, parania, unable t think clearly, md being affected, seeing r hearing things that are nt really there (hallucinatins), suicide attempts, persnality change (psychsis) - pain in the abdmen (stmach), caused by inflammatin f the pancreas - frgetfulness, cnfusin, fitting (seizures), incherent speech, tremr (shaking) - yellw skin r eyes, itching, r pain in the abdmen (stmach) caused by inflammatin f the liver - damage t kidney tubules Psychiatric side effects in additin t thse listed abve include delusins (false beliefs), neursis. Sme patients have cmmitted suicide. These prblems tend t ccur mre ften in thse wh have a histry f mental illness. Always ntify yur dctr immediately if yu have these symptms. Side effects t the liver: If yu are als infected with hepatitis B virus, yu may experience a wrsening f hepatitis after discntinuatin f treatment (see sectin 3). The fllwing side effects are rare (may affect up t 1 in 1,000 peple): - liver failure, in sme cases leading t death r liver transplant. Mst cases ccurred in patients wh already had liver disease, but there have been a few reprts in patients withut any existing liver disease - inflammatin f the kidney, passing a lt f urine and feeling thirsty - back pain caused by kidney prblems, including kidney failure. Yur dctr may d bld tests t see if yur kidneys are wrking prperly - sftening f the bnes (with bne pain and smetimes resulting in fractures) which may ccur due t damage t the kidney tubule cells - fatty liver If yu think that yu may have any f these serius side effects, talk t yur dctr. Mst frequent side effects The fllwing side effects are very cmmn (may affect mre than 1 in 10 peple) - dizziness, headache, diarrhea, feeling sick (nausea), being sick (vmiting) - rashes (including red spts r bltches smetimes with blistering and swelling f the skin), which may be allergic reactins - feeling weak Tests may als shw: - decreases in phsphate levels in the bld - increased levels f creatine kinase in the bld that may result in muscle pain and weakness Other pssible side effects The fllwing side effects are cmmn (may affect up t 1 in 10 peple) - allergic reactins - disturbances f crdinatin and balance - feeling wrried r depressed - difficulty sleeping, abnrmal dreams, difficulty cncentrating, drwsiness - pain, stmach pain 8

9 - prblems with digestin resulting in discmfrt after meals, feeling blated, wind (flatulence) - lss f appetite - tiredness - itching - changes in skin clur including darkening f the skin in patches ften starting n hands and sles f feet Tests may als shw: - lw white bld cell cunt (a reduced white bld cell cunt can make yu mre prne t infectin) - liver and pancreas prblems - increased fatty acids (triglycerides), bilirubin r sugar levels in the bld The fllwing side effects are uncmmn (may affect up t 1 in 100 peple): - breakdwn f muscle, muscle pain r weakness - anaemia (lw red bld cell cunt) - a feeling f spinning r tilting (vertig), whistling, ringing r ther persistent nise in the ears - blurred visin - chills - breast enlargement in males - decreased sexual drive - flushing - dry muth - increased appetite Tests may als shw: - decreases in ptassium in the bld - increases in creatinine in the bld - prteins in urine - increased chlesterl in the bld The breakdwn f muscle, sftening f the bnes (with bne pain and smetimes resulting in fractures), muscle pain, muscle weakness and decreases in ptassium r phsphate in the bld may ccur due t damage t kidney tubule cells. The fllwing side effects are rare (may affect up t 1 in 1,000 peple) - itchy rash t the skin caused by a reactin t sunlight Reprting f side effects If yu get any side effects, talk t yur dctr r pharmacist. This includes any pssible side effects nt listed in this leaflet. Yu can als reprt side effects directly via the Nederlands Bijwerkingen Centrum Lareb, Website: By reprting side effects yu can help prvide mre infrmatin n the safety f this medicine. 5. Hw t stre - Keep this medicine ut f the sight and reach f children. - D nt use this medicine after the expiry date which is stated n the bttle and cartn after {EXP}. The expiry date refers t the last day f that mnth. - This medicine des nt require any special strage cnditins. - Use within 30 days after first pening. - D nt thrw away any medicines via wastewater r husehld waste. Ask yur 9

10 pharmacist hw t thrw away medicines yu n lnger use. These measures will help prtect the envirnment. 6. Cntents f the pack and ther infrmatin What cntains - The active substances are efavirenz, emtricitabine and tenfvir disprxil. Each film-cated tablet cntains 600 mg f efavirenz, 200 mg f emtricitabine and 245 mg f tenfvir disprxil (as succinate). - The ther ingredients in the tablet are cellulse, micrcrystalline (E460), crscarmellse sdium, Type A (E468), hydrxyprpylcellulse (E463), sdium laurilsulfate (E487), magnesium stearate (E470b), plxamer 407 and irn xide red (E172). - The ther ingredients in the tablet film cating are ply(vinyl alchl) (E1203), titanium dixide (E171), macrgl 3350 (E1521), talc (E553b), irn xide red (E172) and irn xide black (E172). What lks like and cntents f the pack film-cated tablets are pink, capsule shaped tablets, plain n bth sides with dimensins f 11 mm x 22 mm apprximately. They are supplied in bttles cntaining 30 tablets, packed in a cartn. Each bttle cntains a silica gel desiccant that must be kept in the bttle t help prtect yur tablets. The silica gel desiccant is cntained in a separate canister and shuld nt be swallwed. The fllwing pack sizes are available: 30 (1 x 30) film-cated tablets 90 (3 x 30) film-cated tablets Nt all pack sizes may be marketed. Marketing Authrisatin Hlder and Manufacturer Marketing Authrisatin Hlder Sandz B.V. Veluwezm AH Almere Nederland Manufacturer Remedica Ltd Aharnn Street, Limassl Industrial Estate Limassl, 3056, Cyprus Lek Pharmaceuticals d.d. Vervškva Ljubljana Slvenië In het register ingeschreven nder: RVG This medicinal prduct is authrised in the Member States f the EEA under the fllwing names: 10

11 Netherlands: Austria: Belgium: Cyprus: Germany: Denmark: Estnia: Finland: Hungary: Iceland: Ireland: Italy: Latvia: Lithuania: Nrway: Pland: Prtugal: Rmania: Sweden: Slvenia: 600 mg/200 mg/245 mg, filmmhulde tabletten 600 mg/200 mg/245 mg Filmtabletten 600 mg/200 mg/245 mg filmmhulde tabletten 600 mg/200 mg/245 mg, Επικαλυμμένα με λεπτό υμένιο δισκία 600 mg/200 mg/245 mg Filmtabletten 600 mg/200 mg/245 mg kalvpäällysteiset tabletit 600 mg/200 mg/245 mg filmtabletta 600 mg/200 mg/245 mg filmuhúðaðar töflur 600 mg/200 mg/245 mg film-cated tablets 600 mg/200 mg/245 mg apvalktās tabletes 600 mg/200 mg/245 mg plėvele dengts tabletės 600 mg/200 mg/245 mg cmprimate filmate 600 mg/200 mg/245 mg filmdragerade tabletter 600 mg/200 mg/245 mg filmsk blžene tablete This leaflet was last revised in Nvember

MEDICATION GUIDE. (canagliflozin) Tablets

MEDICATION GUIDE. (canagliflozin) Tablets MEDICATION GUIDE INVOKANA (in-v-kahn-uh) (canagliflzin) Tablets What is the mst imprtant infrmatin I shuld knw abut INVOKANA? INVOKANA can cause imprtant side effects, including: Dehydratin. INVOKANA can

More information

PATIENT INFORMATION. Rosuvastatin calcium tablets are used along with diet to:

PATIENT INFORMATION. Rosuvastatin calcium tablets are used along with diet to: PATIENT INFORMATION Rsuvastatin Calcium (re-soo-va-stat-in KAL-see-um) Tablets Read this Patient Infrmatin carefully befre yu start taking rsuvastatin calcium tablets and each time yu get a refill. If

More information

PART III: CONSUMER INFORMATION

PART III: CONSUMER INFORMATION IMPORTANT: PLEASE READ PART III: CONSUMER INFORMATION Pr ZERIT Stavudine This leaflet is Part III f a three-part Prduct Mngaph published when ZERIT was apprved fr sale in Canada and is designed specifically

More information

You may have a higher risk of bleeding if you take warfarin sodium tablets and:

You may have a higher risk of bleeding if you take warfarin sodium tablets and: MEDICATION GUIDE Warfarin (WAR-far-in) Sdium (SO-dee-um) Tablets USP The 7.5 mg tablets cntain FD&C Yellw N. 5 (tartrazine), which may cause allergic-type reactins (including brnchial asthma) in certain

More information

PATIENT INFORMATION. effective for the treatment of the flu in people with long-time (chronic) heart problems or breathing problems.

PATIENT INFORMATION. effective for the treatment of the flu in people with long-time (chronic) heart problems or breathing problems. PATIENT INFORMATION capsules, fr ral use fr ral suspensin What is TAMIFLU? TAMIFLU is a prescriptin medicine used t: treat the flu (influenza) in peple 2 weeks f age and lder wh have had flu symptms fr

More information

MEDICATION GUIDE Pioglitazone (pie-oh-glit-ah-zohn) and Metformin (met-fore-min) Hydrochloride Tablets USP

MEDICATION GUIDE Pioglitazone (pie-oh-glit-ah-zohn) and Metformin (met-fore-min) Hydrochloride Tablets USP MEDICATION GUIDE Piglitazne (pie-h-glit-ah-zhn) and Metfrmin (met-fore-min) Hydrchlride Tablets USP Read this Medicatin Guide carefully befre yu start taking piglitazne and metfrmin hydrchlride tablets

More information

MEDICATION GUIDE Pioglitazone and Metformin Hydrochloride (PYE o GLI ta zone and met FOR min HYE-droe- KLOR-ide)Tablets, USP

MEDICATION GUIDE Pioglitazone and Metformin Hydrochloride (PYE o GLI ta zone and met FOR min HYE-droe- KLOR-ide)Tablets, USP MEDICATION GUIDE Piglitazne and Metfrmin Hydrchlride (PYE GLI ta zne and met FOR min HYE-dre- KLOR-ide)Tablets, USP Read this Medicatin Guide carefully befre yu start taking piglitazne and metfrmin hydrchlride

More information

If you have any doubts or queries about your medication, please contact your doctor or pharmacist.

If you have any doubts or queries about your medication, please contact your doctor or pharmacist. Bayer plc Bayer Huse Strawberry Hill Newbury Berkshire RG14 1JA United Kingdm Telephne: +44 (0)1635 563 000 Facsimile: +44 (0)1635 563 393 Cmpany Web Site: http://www.bayer.c.uk Due t regulatry changes,

More information

MEDICATION GUIDE. (fingolimod) capsules

MEDICATION GUIDE. (fingolimod) capsules MEDICATION GUIDE GILENYA (je-len-yah) (finglimd) capsules Read this Medicatin Guide befre yu start using GILENYA and each time yu get a refill. There may be new infrmatin. This infrmatin des nt take the

More information

Package leaflet: Information for the user. Dacepton 5 mg/ml Solution for infusion Apomorphine hydrochloride hemihydrate

Package leaflet: Information for the user. Dacepton 5 mg/ml Solution for infusion Apomorphine hydrochloride hemihydrate Package leaflet: Infrmatin fr the user Daceptn 5 mg/ml Slutin fr infusin Apmrphine hydrchlride hemihydrate Read all f this leaflet carefully befre yu start using this medicine because it cntains imprtant

More information

Package leaflet: Information for the user. CHAMPIX 0.5 mg film-coated tablets CHAMPIX 1 mg film-coated tablets Varenicline

Package leaflet: Information for the user. CHAMPIX 0.5 mg film-coated tablets CHAMPIX 1 mg film-coated tablets Varenicline Package leaflet: Infrmatin fr the user CHAMPIX 0.5 mg film-cated tablets CHAMPIX 1 mg film-cated tablets Varenicline Read all f this leaflet carefully befre yu start taking this medicine because it cntains

More information

Read all of this leaflet carefully before you start taking this medicine.

Read all of this leaflet carefully before you start taking this medicine. Due t regulatry changes, the cntent f the fllwing Patient Infrmatin Leaflet may vary frm the ne fund in yur medicine pack. Please cmpare the 'Leaflet prepared/revised date' twards the end f the leaflet

More information

MEDICATION GUIDE XARELTO (zah-rel-toe) (rivaroxaban) tablets

MEDICATION GUIDE XARELTO (zah-rel-toe) (rivaroxaban) tablets MEDICATION GUIDE XARELTO (zah-rel-te) (rivarxaban) tablets Read this Medicatin Guide befre yu start taking XARELTO and each time yu get a refill. There may be new infrmatin. This Medicatin Guide des nt

More information

MEDICATION GUIDE. Reference ID:

MEDICATION GUIDE. Reference ID: MEDICATION GUIDE GLYXAMBI (glik-sam-bee) (empagliflzin and linagliptin) Tablets Read this Medicatin Guide carefully befre yu start taking GLYXAMBI and each time yu get a refill. There may be new infrmatin.

More information

/0515 Medication Guide Aripiprazole Tablets

/0515 Medication Guide Aripiprazole Tablets 8415721/0515 Medicatin Guide Aripiprazle Tablets (air-eh-pip-rah-zle) Read this Medicatin Guide befre yu start taking aripiprazle tablets and each time yu get a refill. There may be new infrmatin. This

More information

CONSUMER MEDICINE INFORMATION

CONSUMER MEDICINE INFORMATION CONSUMER MEDICINE INFORMATION What is in this leaflet This leaflet answers sme cmmn questins abut CEFTRIAXONE lcp. It des nt cntain all the available infrmatin. It des nt take the place f talking t yur

More information

o New or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe.

o New or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe. MEDICATION GUIDE FLUOXETINE CAPSULES, USP (fl xʹ e teen) 10 mg and 20 mg Read the Medicatin Guide that cmes with fluxetine capsules befre yu start taking it and each time yu get a refill. There may be

More information

MEDICATION GUIDE LEMTRADA (lem-tra-da) (alemtuzumab) Injection for intravenous infusion

MEDICATION GUIDE LEMTRADA (lem-tra-da) (alemtuzumab) Injection for intravenous infusion MEDICATION GUIDE LEMTRADA (lem-tra-da) (alemtuzumab) Injectin fr intravenus infusin Read this Medicatin Guide befre yu start receiving LEMTRADA and befre yu begin each treatment curse. There may be new

More information

MEDICATION GUIDE REVLIMID (rev-li-mid) (lenalidomide) capsules What is the most important information I should know about REVLIMID?

MEDICATION GUIDE REVLIMID (rev-li-mid) (lenalidomide) capsules What is the most important information I should know about REVLIMID? MEDICATION GUIDE REVLIMID (rev-li-mid) (lenalidmide) capsules What is the mst imprtant infrmatin I shuld knw abut REVLIMID? Befre yu begin taking REVLIMID, yu must read and agree t all f the instructins

More information

Vaccine Information Statement: LIVE INTRANASAL INFLUENZA VACCINE

Vaccine Information Statement: LIVE INTRANASAL INFLUENZA VACCINE Vaccine Infrmatin Statement: LIVE INTRANASAL INFLUENZA VACCINE Many Vaccine Infrmatin Statements are available in Spanish and ther languages. See www.immunize.rg/vis. Hjas de Infrmacián Sbre Vacunas están

More information

Package leaflet: Information for the user. GASTROGRAFIN GASTROENTERAL SOLUTION Sodium amidotrizoate and meglumine amidotrizoate

Package leaflet: Information for the user. GASTROGRAFIN GASTROENTERAL SOLUTION Sodium amidotrizoate and meglumine amidotrizoate Due t regulatry changes, the cntent f the fllwing Patient Infrmatin Leaflet may vary frm the ne fund in yur medicine pack. Please cmpare the 'Leaflet prepared/revised date' twards the end f the leaflet

More information

MEDICATION GUIDE. (Interferon alfa-2b)

MEDICATION GUIDE. (Interferon alfa-2b) MEDICATION GUIDE INTRON A (In-trn-aye) (Interfern alfa-2b) Read this Medicatin Guide befre yu start taking INTRON A, and each time yu get a refill. There may be new infrmatin. This infrmatin des nt take

More information

Annex III. Amendments to relevant sections of the Product Information

Annex III. Amendments to relevant sections of the Product Information Changes t the Prduct infrmatin as apprved by the CHMP n 13 Octber 2016, pending endrsement by the Eurpean Cmmissin Annex III Amendments t relevant sectins f the Prduct Infrmatin Nte: These amendments t

More information

New Zealand Consumer Medicine Information. Tramadol hydrochloride immediate release capsules (50 mg) and solution for injection (50 mg/ml, 100 mg/2ml)

New Zealand Consumer Medicine Information. Tramadol hydrochloride immediate release capsules (50 mg) and solution for injection (50 mg/ml, 100 mg/2ml) New Zealand Cnsumer Medicine Infrmatin TRAMAL Tramadl hydrchlride immediate release capsules (50 mg) and slutin fr injectin (50 mg/ml, 100 mg/2ml) What is in this leaflet Please read this leaflet carefully

More information

MEDICATION GUIDE QSYMIA (Kyoo sim ee uh) (phentermine and topiramate extended-release) Capsules CIV

MEDICATION GUIDE QSYMIA (Kyoo sim ee uh) (phentermine and topiramate extended-release) Capsules CIV MEDICATION GUIDE QSYMIA (Ky sim ee uh) (phentermine and tpiramate extended-release) Capsules CIV Read this Medicatin Guide befre yu start taking Qsymia and each time yu get a refill. There may be new infrmatin.

More information

454-8 (Insert) MEDICATION GUIDE ZUBSOLV (Zub-solve) (buprenorphine and naloxone) Sublingual Tablet (CIII) IMPORTANT: Keep ZUBSOLV in a secure place

454-8 (Insert) MEDICATION GUIDE ZUBSOLV (Zub-solve) (buprenorphine and naloxone) Sublingual Tablet (CIII) IMPORTANT: Keep ZUBSOLV in a secure place MEDICATION GUIDE ZUBSOLV (Zub-slve) (buprenrphine and nalxne) Sublingual Tablet (CIII) IMPORTANT: Keep ZUBSOLV in a secure place away frm children. Accidental use by a child is a medical emergency and

More information

Vaccine Information Statement: PNEUMOCOCCAL CONJUGATE VACCINE

Vaccine Information Statement: PNEUMOCOCCAL CONJUGATE VACCINE Vaccine Infrmatin Statement: PNEUMOCOCCAL CONJUGATE VACCINE Many Vaccine Infrmatin Statements are available in Spanish and ther languages. See www.immunize.rg/vis. Hjas de Infrmacián Sbre Vacunas están

More information

Package leaflet: Information for the user. Fragmin Graduated Syringe 10,000 IU/ml Solution for Injection dalteparin sodium

Package leaflet: Information for the user. Fragmin Graduated Syringe 10,000 IU/ml Solution for Injection dalteparin sodium Package leaflet: Infrmatin fr the user Fragmin Graduated Syringe 10,000 IU/ml Slutin fr Injectin dalteparin sdium Read all f this leaflet carefully befre yu start using this medicine because it cntains

More information

Pain relief after surgery

Pain relief after surgery Pain relief after surgery Imprtant infrmatin fr patients www.mchft.nhs.uk We care because yu matter This leaflet is designed t help yu cntrl any pain yu may have at hme fllwing yur peratin. Please read

More information

Suicidal thoughts or actions:

Suicidal thoughts or actions: MEDICATION GUIDE Venlafaxine (VEN la fax een) Hydrchlride Extended-release Capsules USP Read the Medicatin Guide that cmes with venlafaxine hydrchlride extended-release capsulesbefre yu start taking them

More information

RoActemra (tocilizumab) for Giant Cell Arteritis (GCA) subcutaneous (SC) formulation

RoActemra (tocilizumab) for Giant Cell Arteritis (GCA) subcutaneous (SC) formulation RActemra (tcilizumab) fr Giant Cell Arteritis (GCA) subcutaneus (SC) frmulatin What yu shuld knw abut RActemra This brchure prvides key infrmatin t assist in the patient s understanding f the benefits

More information

Medication Guide MORPHINE SULFATE (mor-pheen) Oral Solution (CII)

Medication Guide MORPHINE SULFATE (mor-pheen) Oral Solution (CII) Medicatin Guide MORPHINE SULFATE (mr-pheen) Oral Slutin (CII) IMPORTANT: Keep Mrphine Sulfate Oral Slutin in a safe place away frm children. Accidental use by a child is a medical emergency and can cause

More information

Tendon problems can happen in people of all ages who take levofloxacin. Tendons are tough cords of tissue that connect muscles to bones.

Tendon problems can happen in people of all ages who take levofloxacin. Tendons are tough cords of tissue that connect muscles to bones. Medicatin Guide LEVOFLOXACIN (LEE ve FLOX a sin) INJECTION, 25 mg/ml and LEVOFLOXACIN (LEE ve FLOX a sin) INJECTION in 5% Dextrse fr Intravenus Use Read this Medicatin Guide befre yu start taking levflxacin

More information

PACKAGE LEAFLET INFORMATION FOR THE PATIENT

PACKAGE LEAFLET INFORMATION FOR THE PATIENT PACKAGE LEAFLET INFORMATION FOR THE PATIENT AMPICILLIN 125mg/5ml and 250mg/5ml ORAL SUSPENSION Please read all f this leaflet carefully befre yu start taking this medicine because it cntains imprtant infrmatin

More information

PACKAGE LEAFLET: INFORMATION FOR THE USER TERAZOSIN ACCORD 1 mg TABLETS TERAZOSIN ACCORD 2 mg TABLETS TERAZOSIN ACCORD 5 mg TABLETS TERAZOSIN

PACKAGE LEAFLET: INFORMATION FOR THE USER TERAZOSIN ACCORD 1 mg TABLETS TERAZOSIN ACCORD 2 mg TABLETS TERAZOSIN ACCORD 5 mg TABLETS TERAZOSIN PACKAGE LEAFLET: INFORMATION FOR THE USER TERAZOSIN ACCORD 1 mg TABLETS TERAZOSIN ACCORD 2 mg TABLETS TERAZOSIN ACCORD 5 mg TABLETS TERAZOSIN Read all f this leaflet carefully befre yu start taking this

More information

MEDICATION GUIDE Levofloxacin (lee-voe-flox-a-sin) Tablets, USP 250 mg Tablets, 500 mg Tablets, and 750 mg Tablets

MEDICATION GUIDE Levofloxacin (lee-voe-flox-a-sin) Tablets, USP 250 mg Tablets, 500 mg Tablets, and 750 mg Tablets MEDICATION GUIDE Levflxacin (lee-ve-flox-a-sin) Tablets, USP 250 mg Tablets, 500 mg Tablets, and 750 mg Tablets Read this Medicatin Guide befre yu start taking levflxacin tablets and each time yu get a

More information

PATIENT INFORMATION LEAFLET

PATIENT INFORMATION LEAFLET Ethambutl Hydrchlride/Isniazid/Pyrazinamide/ (Svizera Eurpe BV), TB193 PATIENT INFORMATION LEAFLET Page 1 f 9 Ethambutl Hydrchlride/Isniazid/Pyrazinamide/ (Svizera Eurpe BV), TB193 PATIENT INFORMATION

More information

Package leaflet: Information for the user. Fragmin 10,000 IU/1 ml and 10,000 IU/4 ml Solution for injection dalteparin sodium

Package leaflet: Information for the user. Fragmin 10,000 IU/1 ml and 10,000 IU/4 ml Solution for injection dalteparin sodium Package leaflet: Infrmatin fr the user Fragmin 10,000 IU/1 ml and 10,000 IU/4 ml Slutin fr injectin dalteparin sdium Read all f this leaflet carefully befre yu start using this medicine because it cntains

More information

PACKAGE LEAFLET: INFORMATION FOR THE USER. Moapar mg powder and solvent for prolonged-release suspension for injection triptorelin

PACKAGE LEAFLET: INFORMATION FOR THE USER. Moapar mg powder and solvent for prolonged-release suspension for injection triptorelin PACKAGE LEAFLET: INFORMATION FOR THE USER Mapar 11.25 mg pwder and slvent fr prlnged-release suspensin fr injectin triptrelin Read all f this leaflet carefully befre yu start using this medicine because

More information

My Symptoms and Medical History for Adult Chronic Immune Thrombocytopenia (ITP)

My Symptoms and Medical History for Adult Chronic Immune Thrombocytopenia (ITP) My Symptms and Medical Histry fr Adult Chrnic Immune Thrmbcytpenia (ITP) Call t talk t a registered nurse 1-855-7Nplate (1-855-767-5283), Mnday Friday, 9:00 AM 9:00 PM ET Indicatin Nplate is a man-made

More information

Medication Guide ABSTRAL (AB-stral) CII (fentanyl) Sublingual tablets

Medication Guide ABSTRAL (AB-stral) CII (fentanyl) Sublingual tablets Medicatin Guide ABSTRAL (AB-stral) CII (fentanyl) Sublingual tablets IMPORTANT: D nt use ABSTRAL unless yu are regularly using anther piid pain medicine arund-the-clck fr at least ne week r lnger fr yur

More information

Triumeq (abacavir, dolutegravir and lamivudine) Product Backgrounder for US Media

Triumeq (abacavir, dolutegravir and lamivudine) Product Backgrounder for US Media Triumeq (abacavir, dlutegravir and lamivudine) Prduct Backgrunder fr US Media What is Triumeq and wh is Triumeq fr? Triumeq (abacavir 600mg, dlutegravir 50mg and lamivudine 300mg) is the first dlutegravir-based

More information

PATIENT INFORMATION. (methotrexate) injection, for subcutaneous use

PATIENT INFORMATION. (methotrexate) injection, for subcutaneous use What is Rasuv? PATIENT INFORMATION RASUVO (ruh-soo-vh) (methtrexate) injectin, fr subcutaneus use Rasuv is a single-dse manually-triggered aut-injectr cntaining a prescriptin medicine, methtrexate. Methtrexate

More information

MEDICATION GUIDE SUBOXONE (Sub OX own) (buprenorphine and naloxone) Sublingual Film for Sublingual or Buccal Administration (CIII)

MEDICATION GUIDE SUBOXONE (Sub OX own) (buprenorphine and naloxone) Sublingual Film for Sublingual or Buccal Administration (CIII) MEDICATION GUIDE SUBOXONE (Sub OX wn) (buprenrphine and nalxne) Sublingual Film fr Sublingual r Buccal Administratin (CIII) IMPORTANT: Keep SUBOXONE sublingual film in a secure place away frm children.

More information

Package leaflet: Information for the patient Imuran Powder for Solution for Injection or Infusion 50mg azathioprine

Package leaflet: Information for the patient Imuran Powder for Solution for Injection or Infusion 50mg azathioprine Package leaflet: Infrmatin fr the patient Imuran Pwder fr Slutin fr Injectin r Infusin 50mg azathiprine Read all f this leaflet carefully befre yu start taking this medicine because it cntains imprtant

More information

Influenza (Flu) Fact Sheet

Influenza (Flu) Fact Sheet Influenza (Flu) Fact Sheet What is the flu? The flu is a cntagius respiratry illness caused by influenza viruses. It can cause mild t severe illness, and at times can lead t death. Sme peple, such as lder

More information

PACKAGE LEAFLET: INFORMATION FOR THE USER CHAMPIX 0.5 mg film-coated tablets CHAMPIX 1 mg film-coated tablets. Varenicline

PACKAGE LEAFLET: INFORMATION FOR THE USER CHAMPIX 0.5 mg film-coated tablets CHAMPIX 1 mg film-coated tablets. Varenicline PACKAGE LEAFLET: INFORMATION FOR THE USER CHAMPIX 0.5 mg film-cated tablets CHAMPIX 1 mg film-cated tablets Varenicline Read all f this leaflet carefully befre yu start taking this medicine. - Keep this

More information

Medication Guide SIGNIFOR [sig-na-for] (pasireotide) Injection

Medication Guide SIGNIFOR [sig-na-for] (pasireotide) Injection Medicatin Guide SIGNIFOR [sig-na-fr] (pasiretide) Injectin Read this Medicatin Guide befre yu start using SIGNIFOR and each time yu get a refill. There may be new infrmatin. This infrmatin des nt take

More information

PACKAGE LEAFLET: INFORMATION FOR THE USER

PACKAGE LEAFLET: INFORMATION FOR THE USER (Sanfi-Aventis France), NT001 Suppliers submissin f the SRA apprved text Octber 2016 Name f the medicinal prduct Text bx PACKAGE LEAFLET: INFORMATION FOR THE USER NOTEZINE 100 mg, scred tablets Diethylcarbamazine

More information

Frequently Asked Questions: IS RT-Q-PCR Testing

Frequently Asked Questions: IS RT-Q-PCR Testing Questins 1. What is chrnic myelid leukemia (CML)? 2. Hw des smene knw if they have CML? 3. Hw is smene diagnsed with CML? Frequently Asked Questins: IS RT-Q-PCR Testing Answers CML is a cancer f the bld

More information

CONSENT FOR KYBELLA INJECTABLE FAT REDUCTION

CONSENT FOR KYBELLA INJECTABLE FAT REDUCTION CONSENT FOR KYBELLA INJECTABLE FAT REDUCTION INSTRUCTIONS This is an infrmed cnsent dcument which has been prepared t help yur Dctr infrm yu cncerning fat reductin with an injectable medicatin, its risks,

More information

These are medical emergencies that can cause death. If possible, remove OTFC from the mouth.

These are medical emergencies that can cause death. If possible, remove OTFC from the mouth. MEDICATION GUIDE Oral Transmucsal Fentanyl Citrate (OTFC) CII (fentanyl citrate) ral transmucsal lzenge 200 mcg, 400 mcg, 600 mcg, 800 mcg, 1200 mcg, 1600 mcg IMPORTANT: D nt use Oral Transmucsal Fentanyl

More information

DIABETES AND PANCREATIC EXOCRINE INSUFFICIENCY

DIABETES AND PANCREATIC EXOCRINE INSUFFICIENCY YOU AND YOUR BODY DIABETES AND PANCREATIC EXOCRINE INSUFFICIENCY kk WHY IS THIS LEAFLET FOR YOU? Pancreatic excrine insufficiency (PEI) is imprtant t understand in diabetes care due t the changing functins

More information

PACKAGE LEAFLET: INFORMATION FOR THE USER. Efexor XL 75 mg prolonged-release capsules, hard Efexor XL 150 mg prolonged-release capsules, hard

PACKAGE LEAFLET: INFORMATION FOR THE USER. Efexor XL 75 mg prolonged-release capsules, hard Efexor XL 150 mg prolonged-release capsules, hard PACKAGE LEAFLET: INFORMATION FOR THE USER Efexr XL 75 mg prlnged-release capsules, hard Efexr XL 150 mg prlnged-release capsules, hard Venlafaxine IMPORTANT THINGS YOU SHOULD KNOW ABOUT EFEXOR XL Please

More information

PACKAGE LEAFLET. Page 1 of 10

PACKAGE LEAFLET. Page 1 of 10 PACKAGE LEAFLET Page 1 f 10 Package leaflet: Infrmatin fr the user Ireven 75 mg prlnged-release capsules, hard Ireven 150 mg prlnged-release capsules, hard Venlafaxine Read all f this leaflet carefully

More information

CONSENT FORM - TESTOSTERONE FOR TRANSGENDER CLIENTS

CONSENT FORM - TESTOSTERONE FOR TRANSGENDER CLIENTS CONSENT FORM - TESTOSTERONE FOR TRANSGENDER CLIENTS Yu want t take teststerne t masculinize yur bdy. Befre taking it, there are several things yu need t knw abut. They are the pssible advantages, disadvantages,

More information

Asthma inhalers, medicines and treatments

Asthma inhalers, medicines and treatments Asthma inhalers, medicines and treatments Reliever inhalers Yur Emergency Rescue Reliever Everyne with asthma shuld ALWAYS carry a reliever (blue inhaler) inhaler at all the time s it s n hand in an emergency

More information

Understanding Blood Counts

Understanding Blood Counts Understanding Bld Cunts PMH This pamphlet is fr patients at Princess Margaret Hspital. It will help yu t read and understand the bld cunt infrmatin yu get frm the bld lab. Patient Educatin Imprving Health

More information

Health for Life Chiropractic At Cloverdale Mall Unit # The East Mall Etobicoke, ON, M9B 3Y

Health for Life Chiropractic At Cloverdale Mall Unit # The East Mall Etobicoke, ON, M9B 3Y Health fr Life Chirpractic At Clverdale Mall Unit #143-250 The East Mall Etbicke, ON, M9B 3Y8 416-232-1822 416-232-0060 Child and Adlescent Health Questinnaire Name:_ Birth date: Address:_ Telephne: Medical

More information

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

Read all of this leaflet carefully before you start taking this medicine because it contains important information for you. PACKAGE LEAFLET: INFORMATION FOR THE USER Spranx 10mg/ml Oral Slutin (itracnazle) Read all f this leaflet carefully befre yu start taking this medicine because it cntains imprtant infrmatin fr yu. Keep

More information

A Phase I Study of CEP-701 in Patients with Refractory Neuroblastoma NANT (01-03) A New Approaches to Neuroblastoma Therapy (NANT) treatment protocol.

A Phase I Study of CEP-701 in Patients with Refractory Neuroblastoma NANT (01-03) A New Approaches to Neuroblastoma Therapy (NANT) treatment protocol. SAMPLE INFORMED CONSENT A Phase I Study f CEP-701 in Patients with Refractry Neurblastma NANT (01-03) A New Appraches t Neurblastma Therapy (NANT) treatment prtcl. The wrd yu used thrughut this dcument

More information

Package leaflet: Information for the patient. Padviram 600 mg/200 mg/245 mg film-coated tablets Efavirenz/Emtricitabine/Tenofovir disoproxil

Package leaflet: Information for the patient. Padviram 600 mg/200 mg/245 mg film-coated tablets Efavirenz/Emtricitabine/Tenofovir disoproxil Package leaflet: Information for the patient Padviram 600 mg/200 mg/245 mg film-coated tablets Efavirenz/Emtricitabine/Tenofovir disoproxil Read all of this leaflet carefully before you start taking this

More information

Human papillomavirus (HPV) refers to a group of more than 150 related viruses.

Human papillomavirus (HPV) refers to a group of more than 150 related viruses. HUMAN PAPILLOMAVIRUS This infrmatin may help answer sme f yur questins and help yu think f ther questins that yu may want t ask yur cancer care team; it is nt intended t replace advice r discussin between

More information

Adult Preventive Care Guidelines

Adult Preventive Care Guidelines Adult Preventive Care Guidelines Gundersen is yur partner fr better health. We want t wrk with yu t make sure that yu and yur family are as healthy as pssible. That can be accmplished best if we wrk tgether

More information

3903 Fair Ridge Drive, Suite 209, Fairfax, VA Harry Byrd Hwy, Suite 285, Ashburn, VA *How did you hear about our program?

3903 Fair Ridge Drive, Suite 209, Fairfax, VA Harry Byrd Hwy, Suite 285, Ashburn, VA *How did you hear about our program? 3903 Fair Ridge Drive, Suite 209, Fairfax, VA 22033 44121 Harry Byrd Hwy, Suite 285, Ashburn, VA 220147 *Hw did yu hear abut ur prgram? Patient Histry Patient Name: First Middle: Last: Address: City: State:

More information

Advantage EAP Employee Assistance Program

Advantage EAP Employee Assistance Program Advantage EAP Emplyee Assistance Prgram July 2014 In This Issue What might we face? Symptms f SAD Seasnal changes in biplar disrder Tips fr cmbating summer truble When t seek help Tips fr helping thse

More information

Imaging tests allow the cancer care team to check for cancer and other problems inside the body.

Imaging tests allow the cancer care team to check for cancer and other problems inside the body. IMAGING TESTS This infrmatin may help answer sme f yur questins and help yu think f ther questins that yu may want t ask yur cancer care team; it is nt intended t replace advice r discussin between yu

More information

Percutaneous Nephrolithotomy (PCNL)

Percutaneous Nephrolithotomy (PCNL) Percutaneus Nephrlithtmy (PCNL) What is a percutaneus nephrlithtmy? is the mst effective f the cmmnly perfrmed prcedures fr kidney stnes. It is the best prcedure fr large and cmplex stnes. T perfrm this

More information

ALCAT FREQUENTLY ASKED QUESTIONS

ALCAT FREQUENTLY ASKED QUESTIONS 1. Is fasting required befre taking the Alcat Test? N. It is recmmended t drink water and t avid stimulants like caffeine prir t the test. 2. With regard t testing children, must a child be a certain age

More information

Intravenous Vancomycin Use in Adults Intermittent (Pulsed) Infusion

Intravenous Vancomycin Use in Adults Intermittent (Pulsed) Infusion Backgrund This plicy cvers the use f intravenus vancmycin prescribed as an intermittent (pulsed) infusin. This can be used fr treatment r prphylaxis. Evidence supprting this guidance is detailed belw.

More information

US Public Health Service Clinical Practice Guidelines for PrEP

US Public Health Service Clinical Practice Guidelines for PrEP Webcast 1.3 US Public Health Service Clinical Practice Guidelines fr PrEP P R E S ENTED BY: M A R K T H R U N, M D A S S O C I AT E P R O F E S S O R, U N I V E R S I T Y O F C O L O R A D O, D I V I S

More information

Intravenous Vancomycin Use in Adults Intermittent (Pulsed) Infusion

Intravenous Vancomycin Use in Adults Intermittent (Pulsed) Infusion Intravenus Vancmycin Use in Adults Intermittent (Pulsed) Infusin Backgrund This plicy cvers the use f intravenus vancmycin prescribed as an intermittent (pulsed) infusin. This can be used fr treatment

More information

Osteoporosis Fast Facts

Osteoporosis Fast Facts Osteprsis Fast Facts Fast Facts n Osteprsis Definitin Osteprsis, r prus bne, is a disease characterized by lw bne mass and structural deteriratin f bne tissue, leading t bne fragility and an increased

More information

Swindon Joint Strategic Needs Assessment Bulletin

Swindon Joint Strategic Needs Assessment Bulletin Swindn Jint Strategic Needs Assessment Bulletin Swindn Diabetes 2017 Key Pints: This JSNA gives health facts abut peple with diabetes r peple wh might get diabetes in Swindn. This helps us t plan fr medical

More information

Name of procedure: Removal of submandibular salivary gland

Name of procedure: Removal of submandibular salivary gland Oral facial surgery Surgical prcedure infrmatin leaflet Name f prcedure: Remval f submandibular salivary gland This leaflet explains sme f the benefits, risks and alternatives t the peratin. We want yu

More information

Do you have any of the symptoms listed below? Please circle all that apply.

Do you have any of the symptoms listed below? Please circle all that apply. D yu have any f the symptms listed belw? Please circle all that apply. Parkinsn s Symptms: Truble walking Falls Feet sticking t the flr Tremr Medicatins wearing ff Truble sleeping Vivid dreams Thrashing

More information

Package Leaflet: Information for the user

Package Leaflet: Information for the user Package Leaflet: Infrmatin fr the user Decapeptyl 6-mnth 22.5 mg pwder and slvent fr prlnged-release suspensin fr injectin Triptrelin Read all f this leaflet carefully befre yu start using this medicine

More information

Head and neck cancers are often treated with radiotherapy. Radiotherapy can lead to faster rates of tooth decay and poor healing in the mouth.

Head and neck cancers are often treated with radiotherapy. Radiotherapy can lead to faster rates of tooth decay and poor healing in the mouth. DENTAL EXTRACTION This infrmatin aims t help yu understand the peratin, what is invlved and sme cmmn cmplicatins that may ccur. It may help answer sme f yur questins and help yu think f ther questins that

More information

Patient Information Packet Date:

Patient Information Packet Date: Patient Infrmatin Packet Date: We knw paperwrk is nt fun, but thank yu s much fr taking the time! Last Name: First Name: MI Address: Phne: City State: Zip Cde: Mbile: D.O.B: / / Scial Security: / / Email:

More information

WARNING: FATAL AND SERIOUS TOXICITIES: SEVERE DIARRHEA AND CARDIAC TOXICITIES

WARNING: FATAL AND SERIOUS TOXICITIES: SEVERE DIARRHEA AND CARDIAC TOXICITIES INDICATION FARYDAK (panbinstat) capsules, a histne deacetylase inhibitr, in cmbinatin with brtezmib and dexamethasne, is indicated fr the treatment f patients with multiple myelma wh have received at least

More information

Package leaflet: Information for the patient

Package leaflet: Information for the patient 1 Package leaflet: Infrmatin fr the patient Orxine 25 micrgram tablets Orxine 50 micrgram tablets Orxine 75 micrgram tablets Orxine 100 micrgram tablets Orxine 125 micrgram tablets Orxine 150 micrgram

More information

Completing the NPA online Patient Safety Incident Report form: 2016

Completing the NPA online Patient Safety Incident Report form: 2016 Cmpleting the NPA nline Patient Safety Incident Reprt frm: 2016 The infrmatin cntained within this dcument is in line with the current Data Prtectin Act (DPA) requirements. This infrmatin may be subject

More information

Understanding and Recognizing Anxiety

Understanding and Recognizing Anxiety Understanding and Recgnizing Anxiety Mst peple d nt recgnize their anxiety fr what it is, and instead think there is smething mre serius ging n. Myth: Reading, thinking, and learning abut anxiety will

More information

Appendix 1 Example of Homely Remedy Policy

Appendix 1 Example of Homely Remedy Policy Appendix 1 Example f Hmely Remedy Plicy Hmely Remedy Plicy - EXAMPLE This plicy applies t (insert name f Care Hme) Definitin A hmely (r husehld) remedy is a medicinal prduct fr the shrt-term treatment

More information

Tick fever is a cattle disease caused by any one of the following blood parasites:

Tick fever is a cattle disease caused by any one of the following blood parasites: Tick fever Tick fever is a cattle disease caused by any ne f the fllwing bld parasites: Babesia bvis Babesia bigemina Anaplasma marginale These parasites are all transmitted by the cattle tick (Bphilus

More information

Package leaflet: Information for the user. Entecavir Alvogen 0,5 mg filmomhulde tabletten Entecavir Alvogen 1 mg filmomhulde tabletten Entecavir

Package leaflet: Information for the user. Entecavir Alvogen 0,5 mg filmomhulde tabletten Entecavir Alvogen 1 mg filmomhulde tabletten Entecavir Package leaflet: Information for the user Entecavir Alvogen 0,5 mg filmomhulde tabletten Entecavir Alvogen 1 mg filmomhulde tabletten Entecavir Read all of this leaflet carefully before you start taking

More information

BRCA1 and BRCA2 Mutations

BRCA1 and BRCA2 Mutations BRCA1 and BRCA2 Mutatins ROBERT LEVITT, MD JESSICA BERGER-WEISS, MD ADRIENNE POTTS, MD HARTAJ POWELL, MD, MPH COURTNEY LEVENSON, MD LAUREN BURNS, MSN, RN, WHNP OBGYNCWC.COM v Cancer is a cmplex disease

More information

Efavirenz Mylan 600 mg Film-coated Tablets

Efavirenz Mylan 600 mg Film-coated Tablets PACKAGE LEAFLET: INFORMATION FOR THE USER Efavirenz Mylan 600 mg Film-coated Tablets (efavirenz) Read all of this leaflet carefully before you start taking this medicine because it contains important information

More information

Glaucoma Interviews: Due Tuesday, May 22 nd

Glaucoma Interviews: Due Tuesday, May 22 nd Glaucma Interviews: Due Tuesday, May 22 nd 1) Read the glaucma article well! It will explain what it is, plus tell yu sme symptms and risk factrs. Yu may want t use a highlighter r pen t mark imprtant

More information

Top 10 Causes of Disability

Top 10 Causes of Disability Tp 10 Causes f Disability Disability can happen t anyne, f any age. Thugh sme may be the result f accidents r injuries that are unavidable, many disabilities are the result f diseases and health cnditins

More information

Managing the Symptoms of Stroke

Managing the Symptoms of Stroke Unit 26: Recgnising and Managing the Symptms f Strke Unit reference number: F/616/7312 Level: 2 Unit type: Optinal Credit value: 3 Guided learning hurs: 28 Unit summary A strke can be a life-threatening

More information

NEW PATIENT QUESTIONNAIRE-ADULT

NEW PATIENT QUESTIONNAIRE-ADULT 3700 WASHINGTON AVENUE EVANSVILLE, IN 47750 (812) 485-7680 NEW PATIENT QUESTIONNAIRE-ADULT PART 1. PATIENT INFORMATION Name Hme Phne Date f Birth Scial Security Number Wrk Phne Tday s Date Physicians Caring

More information

Zika Virus. Where has Zika virus been found? Zika in the United States and its territories:

Zika Virus. Where has Zika virus been found? Zika in the United States and its territories: Where has Zika virus been fund? Zika Virus Prir t 2015, Zika virus utbreaks have ccurred in areas f Africa, Sutheast Asia, and the Pacific Islands. In May 2015, the Pan American Health Organizatin (PAHO)

More information

The Dizziness Handicap Inventory ( DHI )

The Dizziness Handicap Inventory ( DHI ) The Dizziness Handicap Inventry ( DHI ) P1. Des lking up increase yur prblem? Yes E2. Because f yur prblem, d yu feel frustrated? Yes F3. Because f yur prblem, d yu restrict yur travel fr business r recreatin?

More information

PHARYNGO-OESOPHAGECTOMY

PHARYNGO-OESOPHAGECTOMY PHARYNGO-OESOPHAGECTOMY This infrmatin aims t help yu understand the peratin, what is invlved and sme cmmn cmplicatins that may ccur. It may help answer sme f yur questins and help yu think f ther questins

More information

Referral Criteria: Inflammation of the Spine Feb

Referral Criteria: Inflammation of the Spine Feb Referral Criteria: Inflammatin f the Spine Feb 2019 1 5.7. Inflammatin f the Spine Backgrund Ankylsing spndylitis and axial spndylarthrpathy are fund in arund 0.3-1.2% f the ppulatin. Spndylarthritis encmpasses

More information

Package leaflet: Information for the user. Ezetimibe STADA 10 mg, tabletten. Ezetimibe

Package leaflet: Information for the user. Ezetimibe STADA 10 mg, tabletten. Ezetimibe Package leaflet: Information for the user Ezetimibe STADA 10 mg, tabletten Ezetimibe Read all of this leaflet carefully before you start taking this medicine because it contains important information for

More information

Getting Started. Learning Guide. with Continuous Glucose Monitoring for the MiniMed 530G with Enlite. CGM Foundations

Getting Started. Learning Guide. with Continuous Glucose Monitoring for the MiniMed 530G with Enlite. CGM Foundations Getting Started with Cntinuus Glucse Mnitring fr the MiniMed 530G with Enlite Learning Guide CGM Fundatins Cntinuus Glucse Mnitring Learning Guide MiniMed 530G with Enlite - Cntinuus Glucse Mnitring Settings

More information

Package leaflet: Information for the user. Dalmevin 50 mg tablets Vildagliptin

Package leaflet: Information for the user. Dalmevin 50 mg tablets Vildagliptin Package leaflet: Information for the user Dalmevin 50 mg tablets Vildagliptin Read all of this leaflet carefully before you start taking this medicine because it contains important information for you.

More information

XYZAL 5 MG FILM-COATED TABLET

XYZAL 5 MG FILM-COATED TABLET XYZAL 5 MG FILM-COATED TABLET Levocetirizine dihydrochloride Read all of this leaflet carefully because it contains important information for you. This medicine is available without prescription. However,

More information