Planning, Priority Setting, and Budget Development for NIH AIDS Research

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1 Planning, Priority Setting, and Budget Development for NIH AIDS Research Robert W. Eisinger, Ph.D. Office of AIDS Research s of Health

2 Focus of Presentation Overview of OAR Priority Setting Process Budget Development Process Trans-NIH Management, Coordination, and Evaluation

3 s of Health Office of the Director Office of AIDS Research on Aging on Alcohol Abuse and Alcoholism of Allergy and Infectious Diseases of Arthritis and Musculoskeletal and Skin Diseases National Cancer Institute of Child Health and Human Development on Deafness and Other Communication Disorders of Dental and Craniofacial Research of Diabetes and Digestive and Kidney Diseases on Drug Abuse of Environmental Health Sciences National Eye Institute of General Medical Sciences National Heart, Lung, and Blood Institute National Human Genome Research Institute of Mental Health of Neurological Disorders and Stroke of Nursing Research of Biomedical Imaging and Bioengineering National Center for Complementary and Alternative Medicine John E. Fogarty International Center National Center for Advancing Translational Sciences National Library of Medicine on Minority Health and Health Disparities Warren Grant Magnuson Clinical Center Center for Information Technology Center for Scientific Review DHHS/NIH/OD/OAR

4 NIH Office of AIDS Research Unique role and legislative authorities Annual trans-nih strategic plan Annual trans-nih budget tied to the strategic plan Trans-NIH coordination, management, and evaluation A unified NIH research front against the AIDS pandemic

5 Annual Trans-NIH Strategic Plan: Setting Scientific Priorities

6 Trans-NIH Plan for HIV-Related Research

7 OAR Planning Process Trans-NIH Coordinating Committees NIH Institutes and Centers Other government entities with research responsibilities Non-government experts from academia, foundations, and industry Community representatives OAR Advisory Council

8 Uses of the Annual Strategic Plan Informs the scientific community, the public, and AIDS-affected communities about the Trans-NIH AIDS research agenda Frames the development of the Trans-NIH AIDS budget Determines the use of NIH AIDS-designated dollars Coding permits tracking and monitoring of expenditures

9 Strategic Plan Areas: Investing in Basic Research - Etiology and Pathogenesis Reducing New Infections - Microbicides - Vaccines - Behavioral and Social Science - Treatment as Prevention Improving Disease Outcomes for HIV- Infected Individuals - Drug Discovery, Development, and Treatment - Research Toward a Cure

10 Strategic Plan Areas: Reducing HIV-Related Disparities Special Populations: - Racial and Ethnic Populations - Women and Girls - Research in International Settings Training, Infrastructure, and Capacity Building Translating Research From Bench to Bedside to Community - Natural History and Epidemiology - Information Dissemination

11 NIH AIDS Research Overarching Priorities A strong foundation of basic science Prevention research, including development of vaccines, microbicides, and behavioral interventions Research toward a cure

12 Current NIH Objectives in Behavioral and Social Science Research Preventive Intervention Research Basic Behavioral and Social Science Research Consequences of HIV Infection Research Methods

13 Behavioral and Social Science Research Portfolio Adherence/compliance/retention in care Stigma, discrimination, poverty, criminal justice Neurocognitive complications Drug and alcohol use; drug interactions Integrate BSSR into design and evaluation of interventions Develop and test innovative interventions reflecting the cultural and social context of the lives of various populations

14 Trans-NIH Budget Development Process

15 Budget Development Process Institutes and Centers (ICs) develop new/expanded program initiatives, with budget requests, for each scientific area OAR reviews ICs initiatives in relation to the Plan and OAR priorities Consultations between ICs and OAR throughout process Budget is developed in consultation between the OAR Director and NIH Director OAR allocates budget levels to each IC

16 Dollars in Millions Total AIDS Funding FY 2005 FY $2,921 $2,902 $2,906 $2,928 $3,019 $3,085 $3,059 $3,075 $3,095 $2,898 $3, CR Fiscal Year 2013 PS 2014 PB

17 IC Funding Distribution FY (dollars in thousands) FY 2014 Institute / FY 2012 FY 2013 President's Center Actual CR Budget NCI $271,692 $273,355 $278,101 NHLBI 67,995 68,431 60,982 NIDCR 20,061 20,301 17,130 NIDDK 30,951 31,140 30,136 NINDS 46,857 47,144 47,229 NIAID 1,572,973 1,583,052 1,631,577 NIGMS 65,202 65,601 69,597 NICHD 144, , ,923 NEI 8,902 8, NIEHS 5,338 5,371 5,122 NIA 5,632 5,666 5,888 NIAMS 4,925 4,955 5,455 NIDCD 1,877 1,888 1,888 NIMH 190, , ,264 NIDA 319, , ,286 NIAAA 28,380 28,554 29,378 NINR 12,642 12,719 12,809 NHGRI 7,130 7,174 7,120 NIBIB 3,699 3,722 1,287 NIMHD 20,446 20,571 21,331 NCCAM 1,610 1,620 1,610 NCATS 68,328 68,766 66,417 FIC 24,241 24,389 27,017 NLM 7,665 7,712 8,412 OD OAR 63,802 64,192 64,392 ORIP 79,844 80,333 80,365 Subtotal, OD 143, , ,757 TOTAL, NIH $3,074,795 $3,094,881 $3,121,716 DHHS/NIH/OD/OAR

18 FY 2014 Funding by Scientific Area of Emphasis of the NIH Plan for HIV-Related Research (dollars in thousands) FY 2012 FY 2013 FY 2014 Area of Emphasis Actual CR PB HIV Microbicides $129,919 $134,627 $133,800 Vaccines 556, , ,966 Behavioral and Social Science 420, , ,209 Therapeutics Therapeutics as Prevention 56,561 58,126 66,026 Drug Discovery, Development and Treatment 650, , ,168 Total, Therapeutics 706, , ,194 Etiolgy and Pathogenesis 668, , ,851 Natural History and Epidemiology 257, , ,385 Training, Infrastructure, and Capacity Building 280, , ,062 Information Dissemination 54,567 50,708 52,249 Total, Budget Authority $3,074,795 $3,094,881 $3,121,716

19 Trans-NIH Management and Coordination Facilitate trans-institute programs Manage multi-institute research Centers for AIDS Research (CFAR) Steering Committee Foster research through designated funds, targeted workshops Identify areas that require focused attention

20 Tracking AIDS Research Funds All ICs are required to code all NIH-funded intramural and extramural AIDS-related research projects All projects coded to objectives of the Plan Information includes: Principal Investigator Institution Funding Mechanism ARIS data uploaded to RCDC

21 Overview OAR has and continues to shift AIDS research program priorities and resources to meet the changing epidemic and scientific opportunities This investment in AIDS research has produced critical scientific advances AIDS research has also assisted prevention and treatment of other important diseases New challenges and opportunities lie ahead

22 Additional Information Additional information is available on the s of Health Office of AIDS Research Web site

23 NIH Turning Discovery Into Health

The NIH STTR Program

The NIH STTR Program May 1, 2015 Matthew Portnoy, Ph.D. SBIR/STTR Program Coordinator, NIH 1 Topics Size of NIH/HHS program Set-asides & spending Research Institutions and Universities in STTR Discretionary