The Lymphatic System and Immunity. Chapters 20 & 21

Save this PDF as:
 WORD  PNG  TXT  JPG

Size: px
Start display at page:

Download "The Lymphatic System and Immunity. Chapters 20 & 21"

Transcription

1 The Lymphatic System and Immunity Chapters 20 & 21

2 Objectives 1. SC.912.L Explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines, and antibiotics. 2. SC.912.L Describe the anatomy and physiology of the lymph system. 3. HE.912.C Evaluate how environment and personal health are interrelated.

3 Objectives 4. SC.912.L Explain the significance of genetic factors, environmental factors, and pathogenic agents to health from the perspectives of both individual and public health. 5. SC.912.L Evaluate the impact of biotechnology on the individual, society and the environment, including medical and ethical issues.

4 Functions Protects us against disease Respond to: environmental pathogens toxins abnormal body cells, such as cancer

5 Pathogens Microscopic organisms that cause disease Ex: viruses bacteria fungi parasites

6 Major Components Lymph a fluid Lymphatic vessels Lymphoid tissues Lymphoid organs Lymphocytes phagocytes

7 Major Components Spleen Thymus Lymphatic vessels Lymph nodes Tonsils Bone marrow

8

9

10

11 Lymphocyte Distribution Wander through tissues Enter blood vessels or lymphatics for transport Can survive many years

12 Lymphoid Tissues Dominated by lymphocytes

13 Lymph Nodes A filter purifies lymph before return to circulation Removes: debris pathogens 99% of antigens

14 Thymus Deteriorates after puberty diminishing effectiveness Site of T cell maturation

15 Spleen Removes abnormal blood cells/blood components Stores iron recycled from RBC s Initiates B and T cell immune response

16 Lymphocytes Produced in lymphoid tissue, organs, and red bone marrow Function: detect problems travel to an injury/infection site Travel in lymph through lymphatic vessels

17 Lymphocytes Make up ~20-30% of circulating leukocytes Most are stored, not circulating 3 classes: T cells B cells NK cells

18 T cells Thymus dependent ~80% of circulating lymphocytes 3 main types: Cytotoxic T cells attacks cells infected by viruses Suppressor T cells inhibit function of T and B cells Helper T cells stimulate function of T and B cells

19

20 B cells Bone marrow derived ~10-15% of circulating lymphocytes Produce and secrete antibodies bind to specific antigens destroys a target

21

22 NK cells Natural killer cells ~5-10% of circulating lymphocytes Attack: foreign cells virus-infected cells cancer cells NK cells Tumor cell

23

24 Body Defenses Provide resistance to fight infection, illness, and disease 2 categories: nonspecific defenses specific defenses

25 Nonspecific Defenses Always work the same way Against any type of invading agent 7 types: physical barriers phagocytic cells immunological surveillance interferons complement inflammation fever

26 Physical Barriers Keep hazardous materials outside the body Examples: skin mucous membranes saliva mucus nasal hair sweat tears

27

28 Phagocytes Attack and remove dangerous microorganisms Examples: microphages macrophages engulf & destroy pathogens bind to pathogen so others can destroy it release toxic chemicals into interstitial fluid

29 Immunological Surveillance Constantly monitors normal tissues NK cells ID and attach to abnormal cells (not selective) can attack cancer/viral-infected cells

30 Interferons Trigger production of antiviral proteins in normal cells do not kill viruses block replication in the cell

31 Complement (C) Proteins Form the complement system Complements actions of antibodies

32 Inflammation Triggers a complex inflammatory response Fever accelerates defenses inhibits some viruses & bacteria Signs & symptoms: swelling, redness, heat, pain

33

34 Specific Defenses Protect against specific pathogens Depend on activities of lymphocytes Specific resistance (immunity) develops after exposure to environmental hazards

35

36 Forms of Immunity Innate present at birth Acquired after birth

37 Acquired Immunity Active antibodies develop after exposure to antigen Passive antibodies are transferred from another source

38 Active Immunity Naturally acquired through environmental exposure to pathogens Induced through vaccines containing pathogens

39 Passive Immunity Naturally acquired antibodies acquired through the mother Induced by an injection of antibodies

40 Effects of Aging Immune system deteriorates increased vulnerability to infections & cancer T cells become less responsive to antigens Immune surveillance against tumor cells declines

Chapter 24 The Immune System

Chapter 24 The Immune System Chapter 24 The Immune System The Immune System Layered defense system The skin and chemical barriers The innate and adaptive immune systems Immunity The body s ability to recognize and destroy specific

More information

Immunity and Infection. Chapter 17

Immunity and Infection. Chapter 17 Immunity and Infection Chapter 17 The Chain of Infection Transmitted through a chain of infection (six links) Pathogen: Disease causing microorganism Reservoir: Natural environment of the pathogen Portal

More information

Chapter 13 Lymphatic and Immune Systems

Chapter 13 Lymphatic and Immune Systems The Chapter 13 Lymphatic and Immune Systems 1 The Lymphatic Vessels Lymphoid Organs Three functions contribute to homeostasis 1. Return excess tissue fluid to the bloodstream 2. Help defend the body against

More information

Campbell's Biology: Concepts and Connections, 7e (Reece et al.) Chapter 24 The Immune System Multiple-Choice Questions

Campbell's Biology: Concepts and Connections, 7e (Reece et al.) Chapter 24 The Immune System Multiple-Choice Questions Campbell's Biology: Concepts and Connections, 7e (Reece et al.) Chapter 24 The Immune System 24.1 Multiple-Choice Questions 1) The body's innate defenses against infection include A) several nonspecific

More information

Nonspecific External Barriers skin, mucous membranes

Nonspecific External Barriers skin, mucous membranes Immune system Chapter 36 BI 103 Plant-Animal A&P Levels of Defense Against Disease Nonspecific External Barriers skin, mucous membranes Physical barriers? Brainstorm with a partner If these barriers are

More information

Nonspecific External Barriers skin, mucous membranes

Nonspecific External Barriers skin, mucous membranes Immune system Chapter 36 BI 103 Plant-Animal A&P Levels of Defense Against Disease Nonspecific External Barriers skin, mucous membranes Physical barriers? Brainstorm with a partner If these barriers are

More information

Topics in Parasitology BLY Vertebrate Immune System

Topics in Parasitology BLY Vertebrate Immune System Topics in Parasitology BLY 533-2008 Vertebrate Immune System V. Vertebrate Immune System A. Non-specific defenses against pathogens 1. Skin - physical barrier a. Tough armor protein KERATIN b. Surface

More information

The Immune System. These are classified as the Innate and Adaptive Immune Responses. Innate Immunity

The Immune System. These are classified as the Innate and Adaptive Immune Responses. Innate Immunity The Immune System Biological mechanisms that defend an organism must be 1. triggered by a stimulus upon injury or pathogen attack 2. able to counteract the injury or invasion 3. able to recognise foreign

More information

Chapter 23 Immunity Exam Study Questions

Chapter 23 Immunity Exam Study Questions Chapter 23 Immunity Exam Study Questions 1. Define 1) Immunity 2) Neutrophils 3) Macrophage 4) Epitopes 5) Interferon 6) Complement system 7) Histamine 8) Mast cells 9) Antigen 10) Antigens receptors 11)

More information

Immunity. Innate & Adaptive

Immunity. Innate & Adaptive Immunity Innate & Adaptive Immunity Innate: response to attack is always the same Mechanical mechanisms Chemical mediators Cellular response Inflammatory response Adaptive: response to attack improves

More information

Innate Immunity. Bởi: OpenStaxCollege

Innate Immunity. Bởi: OpenStaxCollege Innate Immunity Bởi: OpenStaxCollege The vertebrate, including human, immune system is a complex multilayered system for defending against external and internal threats to the integrity of the body. The

More information

immunity defenses invertebrates chapter 49

immunity defenses invertebrates chapter 49 immunity chapter 49 defenses Animal defenses -- thinking about immunity two main types innate immunity acquired immunity mechanism of action non-specific defenses specific defenses invertebrates phagocytosis

More information

Ch. 11: Immune Physiology. 1. Review Immune Organs & Cells. Immune system = The cells and organs involved in defense against pathogens and cancer.

Ch. 11: Immune Physiology. 1. Review Immune Organs & Cells. Immune system = The cells and organs involved in defense against pathogens and cancer. Ch. 11: Immune Physiology Objectives: 1. Review immune organs & cells. 2. Two types of immunity. 3. Understand functions of immune cells (T-cells and B-cells) 4. Understand autoimmunity disorders. 1. Review

More information

The Immune System: Innate and Adaptive Body Defenses Outline PART 1: INNATE DEFENSES 21.1 Surface barriers act as the first line of defense to keep

The Immune System: Innate and Adaptive Body Defenses Outline PART 1: INNATE DEFENSES 21.1 Surface barriers act as the first line of defense to keep The Immune System: Innate and Adaptive Body Defenses Outline PART 1: INNATE DEFENSES 21.1 Surface barriers act as the first line of defense to keep invaders out of the body (pp. 772 773; Fig. 21.1; Table

More information

Endeavour College of Natural Health endeavour.edu.au

Endeavour College of Natural Health endeavour.edu.au Endeavour College of Natural Health endeavour.edu.au BIOH122 Human Biological Science 2 Session 8 Immune System 1 Bioscience Department Endeavour College of Natural Health endeavour.edu.au Session Plan

More information

Lymphatic System. Where s your immunity idol?

Lymphatic System. Where s your immunity idol? Lymphatic System Where s your immunity idol? Functions of the Lymphatic System Fluid Balance Drains excess fluid from tissues Lymph contains solutes from plasma Fat Absorption Lymphatic system absorbs

More information

I. Lines of Defense Pathogen: Table 1: Types of Immune Mechanisms. Table 2: Innate Immunity: First Lines of Defense

I. Lines of Defense Pathogen: Table 1: Types of Immune Mechanisms. Table 2: Innate Immunity: First Lines of Defense I. Lines of Defense Pathogen: Table 1: Types of Immune Mechanisms Table 2: Innate Immunity: First Lines of Defense Innate Immunity involves nonspecific physical & chemical barriers that are adapted for

More information

The Lymphatic System. Innate Immunity

The Lymphatic System. Innate Immunity The Lymphatic System Innate Immunity 1 Types of Immunity Innate (non-specific) immunity Adaptive (specific) immunity The human body has several different ways that it defends itself against infection by

More information

Principles of Anatomy and Physiology

Principles of Anatomy and Physiology Principles of Anatomy and Physiology 14 th Edition CHAPTER 22 The Lymphatic System and Immunity Introduction The purpose of this chapter is to: 1. Understand the lymphatic system structure and function

More information

Chapter 16 Innate Immunity: Nonspecific Defenses of the Host

Chapter 16 Innate Immunity: Nonspecific Defenses of the Host Module 10 Chapter 16 Innate Immunity: Nonspecific Defenses of the Host The concept of immunity Immunity: ability to protect against from microbes and their o Aka, Susceptibility: vulnerability or lack

More information

Immunity. Chapter 38 Part 1

Immunity. Chapter 38 Part 1 Immunity Chapter 38 Part 1 Impacts, Issues Frankie s Last Wish Infection with a common, sexually transmitted virus (HPV) causes most cervical cancers including the one that killed Frankie McCullogh 38.1

More information

UNIT 6: PHYSIOLOGY Chapter 31: Immune System and Disease

UNIT 6: PHYSIOLOGY Chapter 31: Immune System and Disease CORNELL NOTES Directions: You must create a minimum of 5 questions in this column per page (average). Use these to study your notes and prepare for tests and quizzes. Notes will be stamped after each assigned

More information

1. Overview of Innate Immunity

1. Overview of Innate Immunity Chapter 15: Innate Immunity 1. Overview of Innate Immunity 2. Inflammation & Phagocytosis 3. Antimicrobial Substances 1. Overview of Innate Immunity Chapter Reading pp. 449-456 The Body s Defenses The

More information

~ons~ecific Bod~ Defenses and Immunity

~ons~ecific Bod~ Defenses and Immunity ~ons~ecific Bod~ Defenses and Immunity The human body continually attempts to maintain homeostasis by counteracting harmful or disease-producing organisms called pathoqens or the toxins they produce. The

More information

Chapter 24 The Body s Defenses against Pathogens

Chapter 24 The Body s Defenses against Pathogens Chapter 24 The Body s Defenses against Pathogens State Standards Standard 10.a. Standard 10.b. Standard 10.c. Standard 10.d. Standard 10.e. Pathogens Pathogens are They are usually microorganisms - Viruses

More information

Chapter 21: Innate and Adaptive Body Defenses

Chapter 21: Innate and Adaptive Body Defenses Chapter 21: Innate and Adaptive Body Defenses I. 2 main types of body defenses A. Innate (nonspecific) defense: not to a specific microorganism or substance B. Adaptive (specific) defense: immunity to

More information

Biology Lesson 17: The Immune System and Disease

Biology Lesson 17: The Immune System and Disease Biology Lesson 17: The Immune System and Disease Does this organism look like a space alien? A scary creature from a nightmare? In fact, it s a 1-cm long worm that lives in the human body and causes serious

More information

Disease causing organisms Resistance Immunity

Disease causing organisms Resistance Immunity Part 1 Disease causing organisms Resistance Immunity Bacteria Most common pathogens Anthrax Cholera Staphylococcus epidermidis bacteria Bacterial diseases Tuberculosis Cholera Bubonic Plague Tetanus Effects

More information

By Lucy Simpson and Taylor Meyers

By Lucy Simpson and Taylor Meyers By Lucy Simpson and Taylor Meyers Two Types of Immunity Innate immunity- Innate immunity consists of external barriers formed by the skin and mucous membranes, plus a set of internal cellular and chemical

More information

Ch 12. Host Defenses I: Nonspecific Defenses

Ch 12. Host Defenses I: Nonspecific Defenses Ch 12 Host Defenses I: Nonspecific Defenses SLOs Differentiate between innate and adaptive immunity. Define and explain PRRs and PAMPs Differentiate physical from chemical factors, and list examples of

More information

Disease: any change, other than an injury, that disrupts homeostasis. Pathogen: disease-causing agent such as bacteria, virus, etc.

Disease: any change, other than an injury, that disrupts homeostasis. Pathogen: disease-causing agent such as bacteria, virus, etc. The Immune System Disease: any change, other than an injury, that disrupts homeostasis. Pathogen: disease-causing agent such as bacteria, virus, etc. Infectious disease- caused by pathogen Germ theory

More information

Physiology Unit 3. ADAPTIVE IMMUNITY The Specific Immune Response

Physiology Unit 3. ADAPTIVE IMMUNITY The Specific Immune Response Physiology Unit 3 ADAPTIVE IMMUNITY The Specific Immune Response In Physiology Today The Adaptive Arm of the Immune System Specific Immune Response Internal defense against a specific pathogen Acquired

More information

Chapter 17. Immunity. Copyright 2015 Wolters Kluwer Health Lippincott Williams & Wilkins

Chapter 17. Immunity. Copyright 2015 Wolters Kluwer Health Lippincott Williams & Wilkins Chapter 17 Immunity Copyright 2015 Wolters Kluwer Health Lippincott Williams & Wilkins Overview Key Terms allergy dendritic cells mast cell anaphylaxis gamma globulin natural killer (NK) cell antibody

More information

Fluid movement in capillaries. Not all fluid is reclaimed at the venous end of the capillaries; that is the job of the lymphatic system

Fluid movement in capillaries. Not all fluid is reclaimed at the venous end of the capillaries; that is the job of the lymphatic system Capillary exchange Fluid movement in capillaries Not all fluid is reclaimed at the venous end of the capillaries; that is the job of the lymphatic system Lymphatic vessels Lymphatic capillaries permeate

More information

Preventing Communicable Diseases

Preventing Communicable Diseases Preventing Communicable Diseases Notes: Welcome to the Health 9 Lesson: Preventing Communicable Diseases. Please click the next button to continue. Notes: There are many ways to prevent communicable diseases.

More information

Chapter 14. Lymphatic System and Immunity

Chapter 14. Lymphatic System and Immunity Chapter 14 Lymphatic System and Immunity 1 Introduction A. The lymphatic system is comprised of a network of vessels that transport body fluids, the cells and chemicals in those vessels and the organs

More information

Chapter 35 Active Reading Guide The Immune System

Chapter 35 Active Reading Guide The Immune System Name: AP Biology Mr. Croft Chapter 35 Active Reading Guide The Immune System Section 1 Phagocytosis plays an important role in the immune systems of both invertebrates and vertebrates. Review the process

More information

OPTIONAL BIOLOGY 1 STUDY PACKET IMMUNE SYSTEM SC.912.L AA

OPTIONAL BIOLOGY 1 STUDY PACKET IMMUNE SYSTEM SC.912.L AA OPTIONAL BIOLOGY 1 STUDY PACKET IMMUNE SYSTEM SC.912.L.14.52 AA SC.912.L.14.52 AA Explain the basic functions of the human immune system, including specific and nonspecific immune response, vaccines and

More information

Lymphatic vessels purpose arterial side of the capillaries lose more fluid then venous end reabsorbs

Lymphatic vessels purpose arterial side of the capillaries lose more fluid then venous end reabsorbs Chapter 22 The Lymphatic System and Immunity composed of 1. lymphatic vessels 2. specialized cells called lymphocytes 2. numerous lymphoid tissues and organs function of the lymphatic system 1. production,

More information

Essentials of Human Anatomy and Physiology, 11e (Marieb) Chapter 12 The Lymphatic System and Body Defenses Multiple Choice Part I Questions

Essentials of Human Anatomy and Physiology, 11e (Marieb) Chapter 12 The Lymphatic System and Body Defenses Multiple Choice Part I Questions Essentials of Human Anatomy and Physiology, 11e (Marieb) Chapter 12 The Lymphatic System and Body Defenses 12.1 Multiple Choice Part I Questions Using Figure 12.1, identify the following: 1) A lymph capillary

More information

CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport dietary fat. Transport excess tissue fluid back to blood stream

CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES. Transport dietary fat. Transport excess tissue fluid back to blood stream CHAPTER 16: LYMPHATIC SYSTEM AND IMMUNITY OBJECTIVES 1. Name the organs that compose the lymphatic system and give three general functions performed by this system. Bone Marrow Control Disease Thymus Lymph

More information

Station A: YR3 -RESPIRATORY, DIGESTIVE, IMMUNE SYSTEM Sample Tournament. Use the diagram in answering Questions 1-5.

Station A: YR3 -RESPIRATORY, DIGESTIVE, IMMUNE SYSTEM Sample Tournament. Use the diagram in answering Questions 1-5. YR3 -RESPIRATORY, DIGESTIVE, IMMUNE SYSTEM Sample Tournament Station A: Use the diagram in answering Questions 1-5. 1. Give the name and functions of the structure labeled 5 on the diagram. 2. Give the

More information

Introduction to Immunology and the Immune System

Introduction to Immunology and the Immune System Introduction to Immunology and the Immune System Assistant professor Dr. Aida R. Al-Derzi M.B.Ch.B; M.Sc; FICM/Path Dept. of Microbiology/College of Medicine/Baghdad University Introduction to Immunology

More information

CHAPTER VI PDL 101 HUMAN ANATOMY & PHYSIOLOGY. Ms. K. GOWRI. M.Pharm., Lecturer.

CHAPTER VI PDL 101 HUMAN ANATOMY & PHYSIOLOGY. Ms. K. GOWRI. M.Pharm., Lecturer. CHAPTER VI PDL 101 HUMAN ANATOMY & PHYSIOLOGY Ms. K. GOWRI. M.Pharm., Lecturer. Lymphatic System: Lymphatic System which consists of vessels and organs plays two vital roles in our lives: 1) The vessels

More information

White Blood Cells (WBCs)

White Blood Cells (WBCs) YOUR ACTIVE IMMUNE DEFENSES 1 ADAPTIVE IMMUNE RESPONSE 2! Innate Immunity - invariant (generalized) - early, limited specificity - the first line of defense 1. Barriers - skin, tears 2. Phagocytes - neutrophils,

More information

The Lymphatic System and Immunity

The Lymphatic System and Immunity PowerPoint Lecture Slides prepared by Meg Flemming Austin Community College C H A P T E R 14 The Lymphatic System and Immunity Chapter 14 Learning Outcomes 14-1 14-2 14-3 14-4 Distinguish between innate

More information

The Immune System is the Third Line of Defense Against Infection. Components of Human Immune System

The Immune System is the Third Line of Defense Against Infection. Components of Human Immune System Chapter 17: Specific Host Defenses: The Immune Response The Immune Response Immunity: Free from burden. Ability of an organism to recognize and defend itself against specific pathogens or antigens. Immune

More information

REVIEW SHEET HOMEOSTASIS

REVIEW SHEET HOMEOSTASIS 1. What is Homeostasis? The maintenance of stable/constant internal environment despite changing external environment What is another term for Homeostasis? Dynamic Equilibrium Active Balancing 2.What is

More information

AP Biology Campbell - Chapter 43 - The Immune System

AP Biology Campbell - Chapter 43 - The Immune System AP Biology Campbell - Chapter 43 - The Immune System Name What?...Read?...The Overview? Name the three general categories of pathogens: 1. 2. 3. Our immune system is designed to protect us against p Dedicated

More information

Clinical Basis of the Immune Response and the Complement Cascade

Clinical Basis of the Immune Response and the Complement Cascade Clinical Basis of the Immune Response and the Complement Cascade Bryan L. Martin, DO, MMAS, FACAAI, FAAAAI, FACOI, FACP Emeritus Professor of Medicine and Pediatrics President, American College of Allergy,

More information

WHY IS THIS IMPORTANT?

WHY IS THIS IMPORTANT? CHAPTER 16 THE ADAPTIVE IMMUNE RESPONSE WHY IS THIS IMPORTANT? The adaptive immune system protects us from many infections The adaptive immune system has memory so we are not infected by the same pathogen

More information

Medical Virology Immunology. Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University

Medical Virology Immunology. Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University Medical Virology Immunology Dr. Sameer Naji, MB, BCh, PhD (UK) Head of Basic Medical Sciences Dept. Faculty of Medicine The Hashemite University Human blood cells Phases of immune responses Microbe Naïve

More information

4b. Innate (nonspecific) Immunity

4b. Innate (nonspecific) Immunity 4b. Innate (nonspecific) Immunity Chapter 16: Innate (nonspecific) Immunity! Some terms:! Susceptibility: Lack of immunity to a disease.! Immunity: Ability to ward off disease.! immunity: Defenses against

More information

Pathogens and the immune system

Pathogens and the immune system Pathogens and the immune system Veronica Leautaud, Ph.D. vl2@ rice.edu Keck Hall 224 / 232-lab Lecture 8 BIOE 301-Bioengineering and World Health Review of lecture 7 Science Science is the human activity

More information

Chapter 1. Chapter 1 Concepts. MCMP422 Immunology and Biologics Immunology is important personally and professionally!

Chapter 1. Chapter 1 Concepts. MCMP422 Immunology and Biologics Immunology is important personally and professionally! MCMP422 Immunology and Biologics Immunology is important personally and professionally! Learn the language - use the glossary and index RNR - Reading, Note taking, Reviewing All materials in Chapters 1-3

More information

5 Cell recognition and the immune system Support. AQA Biology. Cell recognition and the immune system. Specification reference. Learning objectives

5 Cell recognition and the immune system Support. AQA Biology. Cell recognition and the immune system. Specification reference. Learning objectives Cell recognition and Specification reference 3.2.4 Learning objectives After completing this worksheet you should be able to: understand the concept of self and non-self relate the structure of an antibody

More information

OPTIONAL GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA

OPTIONAL GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA OPTIONAL GRADE 8 STUDY PACKET IMMUNE SYSTEM SC.6.L.14.5 AA SC.6.L.14.5 AA Identify and investigate the general functions of the major systems of the human body (digestive, respiratory, circulatory, reproductive,

More information

4b. Innate (nonspecific) Immunity

4b. Innate (nonspecific) Immunity 4b. Innate (nonspecific) Immunity Chapter 16: Innate (nonspecific) Immunity! Some terms:! Susceptibility: Lack of immunity to a disease.! Immunity: Ability to ward off disease.! Innate immunity: Defenses

More information

Lines of Defense. Immunology, Immune Response, and Immunological Testing. Immunology Terminology

Lines of Defense. Immunology, Immune Response, and Immunological Testing. Immunology Terminology Immunology, Immune Response, and Immunological Testing Lines of Defense If the First and Second lines of defense fail, then the Third line of defense is activated. B and T lymphocytes undergo a selective

More information

SECTION 14 - PRINCIPLES OF IMMUNOLOGY TABLE OF CONTENTS

SECTION 14 - PRINCIPLES OF IMMUNOLOGY TABLE OF CONTENTS SECTION 14 - PRINCIPLES OF IMMUNOLOGY TABLE OF CONTENTS 1.0 THE IMMUNE SYSTEM... 1 1.1 INTRODUCTION... 1 1.2 CELLS OF THE IMMUNE SYSTEM... 1 1.3 LYMPHATIC SYSTEM... 1 1.4 TYPES OF IMMUNITY (SEE FIGURE

More information

Pathogens and the Immune System The War Begins. The Enemy - immune system responds to antigens ( ); for us this means a pathogen

Pathogens and the Immune System The War Begins. The Enemy - immune system responds to antigens ( ); for us this means a pathogen Pathogens and the Immune System The War Begins The Enemy immune system responds to antigens ( ); for us this means a pathogen pathogens ( ) try to colonize your body bacterial pathogens produce toxins

More information

Immune Surveillance. Immune Surveillance. Immune Surveillance. Neutrophil granulocytes Macrophages. M-cells

Immune Surveillance. Immune Surveillance. Immune Surveillance. Neutrophil granulocytes Macrophages. M-cells he immune system is everywhere Some organs have developed strategies towards the immune system to keep it out or to put it under control Immune privileged organs: Brain Eye estis hyroid gland Humoral immunity

More information

LEARNING OBJECTIVES Ø Describe the process or chain of infection. Ø Discuss the body s defenses for fighting infection and disease

LEARNING OBJECTIVES Ø Describe the process or chain of infection. Ø Discuss the body s defenses for fighting infection and disease Infectious Diseases LEARNING OBJECTIVES Ø Describe the process or chain of infection Ø Discuss the body s defenses for fighting infection and disease Ø Discuss the spread of infectious disease Ø Explain

More information

Immune System Guarding Against Disease

Immune System Guarding Against Disease Immune System Guarding Against Disease W O R K Pathogens are everywhere. What are pathogens and how does your body defend itself against pathogens? T O G E T H E R Pathogen An infectious agent that causes

More information

Lymphatic System. The most important functions of the lymphatic system are: Maintenance of fluid balance in the internal environment

Lymphatic System. The most important functions of the lymphatic system are: Maintenance of fluid balance in the internal environment Lymphatic System Lymphatic System The lymphatic system is a complex network of connective tissue that is composed of: Lymphoid organs Lymph nodes Lymph ducts Lymph vessels Lymph capillaries Lymphatic System

More information

Independent Study Guide The Innate Immune Response (Chapter 15)

Independent Study Guide The Innate Immune Response (Chapter 15) Independent Study Guide The Innate Immune Response (Chapter 15) I. General types of immunity (Chapter 15 introduction) a. Innate i. inborn ii. pattern recognition b. Adaptive i. "learned" through exposure

More information

Interactions Among Animal Systems. Biology 10(A)

Interactions Among Animal Systems. Biology 10(A) Interactions Among Animal Systems Biology 10(A) Interactions Among Animal Systems Learning Objectives Identify major organ systems in animals Describe the interactions that occur among systems to carry

More information

Introduction to the immune system Innate humoral immunity

Introduction to the immune system Innate humoral immunity Introduction to the immune system Innate humoral immunity Bartosz Wojciuk Immunology course for the 2nd year Medical Faculty students Pomeranian Medical University Academic year 2017/2018, winter semester

More information

Kinds of Resistance. Defense Mechanisms. Lec 7 (Ch14, 15): Nonspecific Immunity Host Defenses. 2 Major divisions: 3 Lines of Defense

Kinds of Resistance. Defense Mechanisms. Lec 7 (Ch14, 15): Nonspecific Immunity Host Defenses. 2 Major divisions: 3 Lines of Defense Lec 7 (Ch14, 15): Nonspecific Immunity Host Defenses Topics - Defense Mechanisms (innate, acquired) - Systems (anatomic, immunological) - Non-specific immunity (general response) 1 Kinds of Resistance

More information

Lymphatic System and Immunity

Lymphatic System and Immunity Lymphatic System and Immunity Structure of the Lymphatic System Lymph - Straw-colored, similar to plasma - Interstitial fluid in spaces between cells - Composed of water, lymphocytes. Oxygen, digested

More information

The Lymphoid System Pearson Education, Inc.

The Lymphoid System Pearson Education, Inc. 23 The Lymphoid System Introduction The lymphoid system consists of: Lymph Lymphatic vessels Lymphoid organs An Overview of the Lymphoid System Lymph consists of: Interstitial fluid Lymphocytes Macrophages

More information

LYMPHATIC SYSTEM LAB WORKSHEET

LYMPHATIC SYSTEM LAB WORKSHEET NAME: Pd 4 DATE: LYMPHATIC SYSTEM LAB WORKSHEET ACTIVITY 1: Answer the following questions 1. What is lymph? What is the normal composition of lymph? How does the composition of lymph differs from that

More information

An introduction to innate immunity

An introduction to innate immunity An introduction to innate immunity Hans-Peter Duerr Department of Medical Biometry University of Tübingen, Germany Tübingen, 27. April 2006 1 / 17 Motive: superinfection with helminths Parasite establishment

More information

Chapter 21 The Immune System: Innate and Adaptive Body Defenses

Chapter 21 The Immune System: Innate and Adaptive Body Defenses Chapter 21 The Immune System: Innate and Adaptive Body Defenses 1/25/2016 1 Annie Leibovitz/Contact Press Images The Immune System Immune system provides resistance to disease Made up of two intrinsic

More information

Immunology and Immunotherapy 101 for the non-immunologist

Immunology and Immunotherapy 101 for the non-immunologist Immunology and Immunotherapy 101 for the non-immunologist SITC Advances in Immunotherapy Seattle, WA 2016 Laura QM Chow Associate Professor University of Washington Associate Professor, Fred Hutchison

More information

The Immune System. Chapter 43. Biology Eighth Edition Neil Campbell and Jane Reece. PowerPoint Lecture Presentations for

The Immune System. Chapter 43. Biology Eighth Edition Neil Campbell and Jane Reece. PowerPoint Lecture Presentations for Chapter 43 The Immune System PowerPoint Lecture Presentations for Biology Eighth Edition Neil Campbell and Jane Reece Lectures by Chris Romero, updated by Erin Barley with contributions from Joan Sharp

More information

The Circulatory System. The Circulatory System. The circulatory system distributes materials such as oxygen and nutrients throughout the body.

The Circulatory System. The Circulatory System. The circulatory system distributes materials such as oxygen and nutrients throughout the body. The Circulatory System Melissa Zelaya Spring 2010 Senior Seminar The circulatory system distributes materials such as oxygen and nutrients throughout the body. The Circulatory System The heart muscular

More information

IMMUNITY. Stage 1. Stage 2. Stage 3. Stage 4. (a) Describe one method by which antibodies specific to a disease might have been produced.

IMMUNITY. Stage 1. Stage 2. Stage 3. Stage 4. (a) Describe one method by which antibodies specific to a disease might have been produced. QUESTIONSHEET 1 The diagram shows a system for detecting the presence of a disease organism in the blood of an infected person. Stage 1 Antibody specific to the disease organism is bound to the surface

More information

Equine biological systems

Equine biological systems Equine biological systems Pack 20 The lymphatic system Pack Code: EBS20 This pack will help you to: List the functions of the lymphatic system. Describe the components of the lymphatic system.. www.lbcnc.org.uk

More information

Introduction to Immune System

Introduction to Immune System Introduction to Immune System Learning outcome You will be able to understand, at a fundamental level, the STRUCTURES and FUNCTIONS of cell surface and soluble molecules involved in recognition of foreign

More information