Clinical Case Scenario. HIVeEducation Workshop, Sint Maarten 2009
|
|
- Lorin Cox
- 5 years ago
- Views:
Transcription
1 Clinical Case Scenario HIVeEducation Workshop, Sint Maarten 2009
2 Background Mrs. S is a 34 year-old woman who was referred from the VCT center after testing HIV positive three weeks ago. Her husband recently died from cryptococcal meningitis; during his hospitalization he tested positive for HIV, causing her to pursue testing.
3 Background, continued Mrs. S s past medical history is remarkable for an appendectomy performed at age 18. She has otherwise been well until her diagnosis for tuberculosis 4 months ago. At that time she began four-drug treatment for TB, and is currently taking isoniazid and ethambutol. HIV testing was recommended and refused at the time of TB diagnosis. Other than TB treatment, she is taking no medications.
4 Allergies She is allergic to trimethoprim/sulfamethoxazole (Bactrim) which causes a diffuse erythematous maculopapular rash.
5 Physical exam Her physical exam is notable for a thin, welldeveloped woman in no acute distress. HEENT exam reveals candida on the tongue and buccal mucosa. Heart, lung, and abdomen exam are normal.
6 Hemoglobin11.7 ALT39 White blood cell4.8 AST47 Neutrophils74% Lymphocytes20% Monocytes6% Platelets167,000 HIV+ Laboratory test
7 For this patient, what evidence (history, physical examination, and/or laboratory data) supports beginning antiretroviral therapy (ART)? Thrush; oral candida (candidiasis) Low total lymphocyte (lymphs) count (TLC); total TLC = 960; TLC, 1,200 Tuberculosis within past two years; recent tuberculosis HIV+ Social history: husband died of cryptococcal meningitis-likely more advanced disease, so wife likely has been infected for a while.
8 Do you identify any barriers to good ARV adherence? If so, what would you recommend to address the barrier's? Widowed; limited (or unknown) support system TB (tuberculosis) meds; concurrent TB treatment Finances; limited money Limited knowledge of HIV Not previously ill; good baseline health; no symptoms Potential childrearing responsibilities; potential pregnancy In favor of adherence she opted for testing when her husband was positive In favor of adherence by taking TB drugs she is demonstrating her capacity to take drugs over time The fact that she refused to go for testing The reaction to Septrin may make her hesitant to take more drugs
9 What antiretroviral medications would you initiate? AZT (Zidovudine) + 3TC + nevirapine (patient already has anemia which might be worsened by AZT) Stavudine (d4t), lamivudine (3TC) and Nevirapine) (lowest cost)
10 What antiretroviral medications would you initiate? Acceptable alternate regimens: AZT (Zidovudine) + 3TC + efavirenz (patient already has anemia which could be worsened by AZT) d4t (Stavudine) + 3TC + nevirapine more expensive than whats above and need to make sure she isn t pregnant or expecting to become pregnant d4t (Stavudine) + 3TC + efavirenz
11 What antiretroviral medications would you initiate? Not acceptable Less than three medications Medications which are not antiretrovirals
12 What toxicities could be associated with the antiretroviral medication s AZT Anemia Nail changes Macrocytosis Fatigue Nausea; GI disturbance Lactic acidosis Hepatic (liver) toxicity myopathy you chose?
13 What toxicities could be associated with the antiretroviral medication s you chose? 3TC Lactic acidosis Hepatic (liver) toxicity Nausea; GI disturbance Rash (rare)
14 What toxicities could be associated with the antiretroviral medication s you chose? d4t Nausea; GI disturbance Peripheral neuropathy Lipodystrophy Pancreatitis Lactic acidosis Hepatic (liver) toxicity
15 What toxicities could be associated with the antiretroviral medication s Efavirenz you chose? Nausea; GI disturbance Central nervous system (CNS) hyperactivity; abnormal dreams; hallucination Rash Hepatic (liver) toxicity Teratogenic (in monkeys)
16 What toxicities could be associated with the antiretroviral medication s you chose? Nevirapine Rash Nausea; GI disturbance Hepatic (liver) toxicity
17 Additional Information You and your patient decide to begin antiretroviral therapy. Ten days after starting therapy, she calls to report that she has developed a red, pruritic rash covering most of her trunk and extremities. She denies fever, myalgias, other constitutional symptoms, and says she feels well except for the rash.
18 Which antiretroviral medication(s) would be the most likely explanation for her symptoms? Best answer Nevirapine Acceptable answer Efavirenz
19 How would you manage the problem of her rash? Check LFTs (liver function tests) Treat with diphenhydramine (Benadryl) Treat with steroid cream Check hemoglobin and/or hematocrit Continue ART Observe for worsening (worse rash; fever, abdominal pain; mucosal involvement [oral rash, mouth lesions]) Make sure patient started nevirapine with only once daily-if not reduce dose to once daily and when rash resolves increase to twice daily
nevirapine, stavudine and lamivudine
nevirapine, stavudine and lamivudine Information on starting treatment with: nevirapine (NVP) + stavudine (d4t) + lamivudine (3TC) Nevirapine, stavudine and lamivudine (non-fixed dose) 2 Lead in dosing
More informationnevirapine, zidovudine and lamivudine
nevirapine, zidovudine and lamivudine a fixed dose ART combination for HIV treatment http://www.aidsmap.com/hatip nevirapine. zidovudine and lamivudine (non-fixed dose) 2 Information on starting treatment
More informationEfavirenz, stavudine and lamivudine
efavirenz, stavudine, lamivudine: 1 efavirenz, stavudine and lamivudine First line ART treatment for HIV infection Efavirenz, stavudine and lamivudine efavirenz, stavudine, lamivudine: 2 Slide 1 Information
More informationPrinciples of Antiretroviral Therapy
Principles of Antiretroviral Therapy Ten Principles of Antiretroviral Therapy Skills Building Workshop: Clinical Management of HIV Infection and Antiretroviral Therapy, 11 th ICAAP, November 21st, 2011,
More informationNational Clinical Symposium
National Clinical Symposium Drug Toxicity Workshop September 14-15, 2006 NCHADS Social Health Clinic Case Study NCHADS Social Health Clinic 1 Case study drug toxicity 34 year-old woman, diagnosed HIV +ve+
More informationANTIRETROVIRAL (ART) DRUG INFORMATION FOR HEALTH CARE PROFESSIONAL
ZIDOVUDINE (AZT, Retrovir ) Benefits of zidovudine: Zidovudine (ZDV) is an antiretroviral drug that slows the growth of the HIV virus. It has shown in a large randomized, multicentre study to decrease
More informationd4t-3tc-nvp stavudine lamivudine nevirapine Morning: d4t-3tc-nvp (Combined tablet) Evening: d4t and 3TC (2 separate tablets)
Now, you are on ART d4t-3tc-nvp stavudine lamivudine nevirapine Week 1-2 d4t-3tc-nvp (Combined tablet) d4t and 3TC (2 separate tablets) Week 3 and after Combined tablet Combined tablet Remember that: If
More informationDifference of opinion? Michelle Moorhouse 24 Sep 2014
Difference of opinion? Michelle Moorhouse 24 Sep 2014 Meet NN 52 years, female Nurse in pre-art clinic Referred Feb 2012 by dermatologist History of severe reactions to ART Erythema and bullous eruptions
More informationMDR TB/HIV INTEGRATION MDR TB WORKSHOP 18 SEPTEMBER 2015
MDR TB/HIV INTEGRATION MDR TB WORKSHOP 18 SEPTEMBER 2015 HIV & MDR :Impact of early ART initiation Adjusted HR: 0.14; p = 0.042 86% reduction in mortality with ART Initiation during MDR-TB treatment 2015
More informationImmune Reconstitution Inflammatory Syndrome. Dr. Lesego Mawela
Immune Reconstitution Inflammatory Syndrome Dr. Lesego Mawela TOPICS FOR DISCUSSION IRIS Case Epidermiology Pathogenesis of IRIS Risk factors for IRIS Epidemiology of IRIS Health system burden of IRIS
More informationINITIATING ART IN CHILDREN: Follow the six steps
INITIATING ART IN CHILDREN: Follow the six steps STEP 1: DECIDE IF THE CHILD HAS CONFIRMED HIV INFECTION Child < 18 months: HIV infection is confirmed if the PCR is positive and the VL is more than 10,000
More informationTreatment experience in South Africa. Dr Ian Sanne Clinical HIV Research Unit University of the Witwatersrand
Treatment experience in South Africa Dr Ian Sanne Clinical HIV Research Unit University of the Witwatersrand Overview South African Prevalence Adherence Combination ddi + d4t Nevirapine Hepatotoxicity
More informationmedical monitoring: clinical monitoring and laboratory tests
medical monitoring: clinical monitoring and laboratory tests Purpose of monitoring Check on the physical, psychological and emotional condition of the patient Detect other treatable conditions Identify
More informationDescription of d4t toxicities among 3 OI/ART clinics patients on ARV in Cambodia
Description of d4t toxicities among 3 OI/ART clinics patients on ARV in Cambodia First Phnom Penh Symposium on HIV Medicine Dr. Khim Sam Ath, MSF Belgium Introduction Scale up of access to HAART has become
More informationBASIC HIV COURSE EXAMINATION
[Pick the date] HU CFAR BASIC HIV COURSE EXAMINATION [Type the author name] The mission of the Harvard University Center for AIDS Research (HU CFAR) is to expand, promote, and facilitate collaborative,
More informationTHE SOUTH AFRICAN ANTIRETROVIRAL TREATMENT GUIDELINES 2010
THE SOUTH AFRICAN ANTIRETROVIRAL TREATMENT GUIDELINES 2010 The South African Antiretroviral Treatment Guidelines 2010 Goals of the programme Achieve best health outcomes in the most cost-efficient manner
More informationADVANCED CLINICAL CARE JOB AIDES VERSION1- MARCH 2018
ADVANCED CLINICAL CARE JOB AIDES VERSION1- MARCH 2018 DISCLAIMER The Advanced Clinical Care (ACC), Job Aides was made possible by the support of the American People through the Centres for Disease Control
More informationPost-Exposure Prophylaxis Review for International Visitors
Post-Exposure Prophylaxis Review for International Visitors Case Presentation 27 yo nurse presents to Urgent Care for a needlestick 2 days ago from a diabetic lancet. Source patient (SP): 35 yo male known
More informationABACAVIR HYPERSENSITIVITY REACTION
ABACAVIR HYPERSENSITIVITY REACTION Key Risk Minimisation Points: Abacavir Hypersensitivity Reaction (HSR) Abacavir is associated with a risk for hypersensitivity reactions (HSR) characterised by fever
More informationSA TB Guidelines The interface with Advanced Clinical Care
SA TB Guidelines The interface with Advanced Clinical Care Dr Kogie Naidoo (MBCHB, PHD) Head: CAPRISA Treatment Research Programme Honorary Lecturer - UKZN Department of Public Heath Medicine Annual Workshop
More informationTB/HIV CO-INFECTION ADULT & CHILDREN (INCLUDING INH PROPHYLAXIS) ART Treatment Guideline Training 31 st January to 4 th February, 2011
TB/HIV CO-INFECTION ADULT & CHILDREN (INCLUDING INH PROPHYLAXIS) ART Treatment Guideline Training 31 st January to 4 th February, 2011 OUTLINE Background Global Incidence The Problem" The 3 I s Drug Resistant
More informationClinical Management Guidelines 2012
Central American Course Monitoring and Evaluation for HIV/AIDS Policy and Program Management 1 2 3 4 Module 1 Unit 1 Clinical Management Guidelines 2012 National TB, HIV/AIDS & other STIs Programme Ministry
More informationWhat Women Need to Know: The HIV Treatment Guidelines for Pregnant Women
: The HIV Treatment Guidelines for Pregnant Women : The HIV Treatment Guidelines for Pregnant Women What Women Need to Know: Prepared by Elaine Gross, RN, MS, CNS-C National Pediatric & Family HIV Resource
More informationtreatment during pregnancy and breastfeeding
treatment during pregnancy and breastfeeding Topics covered Introduction. Preventing parent-to-child transmission. AZT as a single therapy. Treatment begun late in pregnancy. Nevirapine for mothers and
More informationFurther publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for
Further publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for South-East Asia, World Health House, Indraprastha Estate,
More informationAntiretroviral Drugs. Paediatric Palliative Care For Home Based Carers. Funded by British High Commission, Pretoria Small Grant Scheme
Antiretroviral Drugs Paediatric Palliative Care For Home Based Carers Funded by British High Commission, Pretoria Small Grant Scheme Thembi Thembi is two years old and was born with HIV. In the past, the
More informationPOST-EXPOSURE PROPHYLAXIS, PRE-EXPOSURE PROPHYLAXIS, & TREATMENT OF HIV
POST-EXPOSURE PROPHYLAXIS, PRE-EXPOSURE PROPHYLAXIS, & TREATMENT OF HIV DISCLOSURE Relevant relationships with commercial entities none Potential for conflicts of interest within this presentation none
More information0% 0% 0% Parasite. 2. RNA-virus. RNA-virus
HIV/AIDS and Treatment Manado, Indonesia 16 november HIV [e] EDUCATION HIV is a 1. DNA-virus 2. RNA-virus 3. Parasite 0% 0% 0% DNA-virus RNA-virus Parasite HIV HIV is a RNA-virus. HIV is an RNA virus which
More informationTreatment and Monitoring
Treatment and Monitoring Disclosures We have no actual or potential conflicts of interest in relation to this presentations. We have no financial relationships to disclose. Learning Objectives After this
More informationWESTERN CAPE ART GUIDELINES PRESENTATION 2013
WESTERN CAPE ART GUIDELINES PRESENTATION 2013 The WC guidelines are based on SA National ART guidelines dated 24th March 2013 Acknowledgement goes to members of the Adult and Paediatric HAST policy advisory
More informationTreatment strategies for the developing world
David A Cooper National Centre in HIV Epidemiology and Clinical Research The University of New South Wales Sydney, Australia First line standard of care First line in the developing world First line failure
More informationContinuing Education for Pharmacy Technicians
Continuing Education for Pharmacy Technicians HIV/AIDS TREATMENT Michael Denaburg, Pharm.D. Birmingham, AL Objectives: 1. Identify drugs and drug classes currently used in the management of HIV infected
More informationClinical guidelines for the management of HIV/AIDS in adults and adolescents 15 years. SAHIVCS - CME 13/06/15 DR.Henry Sunpath
Clinical guidelines for the management of HIV/AIDS in adults and adolescents 15 years SAHIVCS - CME 13/06/15 DR.Henry Sunpath 1 Introduction What is new? Goals and objectives Guiding principles HIV continuum
More informationUPDATE TRAINING ARV TREATMENT GUIDELINES TRAINERS CASE STUDIES & ANSWER GUIDE
UPDATE TRAINING ARV TREATMENT GUIDELINES TRAINERS CASE STUDIES & ANSWER GUIDE 3/13/2013 Contents Group Work Instructions... 2 PMTCT... 3 Case Study 1: Unbooked Pregnant Women... 3 Case Study 2: First ANC
More informationImportant Safety Information About TRUVADA for a Pre-exposure Prophylaxis (PrEP) Indication. For Healthcare Providers
Important Safety Information About TRUVADA for a Pre-exposure Prophylaxis (PrEP) Indication For Healthcare Providers About TRUVADA for a PrEP Indication INDICATION AND PRESCRIBING CONSIDERATIONS TRUVADA,
More informationA Genetic Test to Screen for Abacavir Hypersensitivity Reactions
The Future of Pharmacogenetics in HIV Clinical Care A Genetic Test to Screen for Abacavir Hypersensitivity Reactions Evan Collins & Misty Bath CANAC/ACIIS 15 th Annual Conference Vancouver, BC April 2007
More informationClinical Manifestations of HIV
HIV Symptoms Diane Havlir, MD Professor of Medicine and Chief, HIV/AIDS Division University of California, San Francisco (UCSF) WorldMedSchool; July 2, 2013 1 Clinical Manifestations of HIV! Result from
More informationCLAUDINE HENNESSEY & THEUNIS HURTER
HIV/AIDS/TB CLAUDINE HENNESSEY & THEUNIS HURTER KEY TERMS Do these sound familiar? What strange terms do you hear in the clinics? Any others to add?? HIV AIDS Viral Load & suppression CD4 count Regimen
More information3TC (lamivudine, Epivir)
3TC (lamivudine, Epivir) Summary 3TC is a type of antiretroviral drug called a nucleoside analogue (or nuke ). 3TC can cause nausea, headache, diarrhea, vomiting and weakness; however, it causes few side
More information3TC (lamivudine, Epivir)
FACTSHEET 3TC (lamivudine, Epivir) Summary 3TC is a type of antiretroviral drug called a nucleoside analogue (or nuke ). 3TC can cause nausea, headache, diarrhea, vomiting and weakness; however, it causes
More informationWorld Bank Training Program on HIV/AIDS Drugs
World Bank Training Program on HIV/AIDS Drugs Training Module 3 Selection and Quantification based on the World Bank document Battling HIV/AIDS: A Decision Maker s Guide to the Procurement of Medicines
More informationInt. J. Adv. Res. Biol. Sci. (2017). 4(8): 28-35
Int. J. Adv. Res. Biol. Sci. (1). (8): 835 International Journal of Advanced Research in Biological Sciences ISSN: 38869 www.ijarbs.com DOI: 1.19/ijarbs Coden: IJARQG(USA) Volume, Issue 8 1 Research Article
More informationSasisopin Kiertiburanakul, MD, MHS
What s Newin Antiretroviral Therapy? Sasisopin Kiertiburanakul, MD, MHS Division of Infectious Diseases Department of Medicine Faculty of Medicine Ramathibodi Hospital Mahidol University Rotating RCPT,
More informationIntroduction to TB Nurse Case Management Online February 4, 11, 18 and 25, 2015
Introduction to TB Nurse Case Management Online February 4, 11, 18 and 25, 2015 Initiation Phase Part 1 Ginny Dowell, RN, BSN February 4, 2015 Ginny Dowell RN, BSN has the following disclosures to make:
More informationNewly diagnosed HIV patient. Dr. Heila Redpath 06 FEBRUARY 2014
Newly diagnosed HIV patient Dr. Heila Redpath 06 FEBRUARY 2014 PRIMARY HIV INFECTION: SEROCONVERSION SYMPTOMATIC HIV INFECTION AND AIDS ASYMPTOMATIC LATENT INFECTION CLOSED CIRCLES: CD4 cells OPEN
More informationFixed Dose Combination a Simplified Approach to Pediatric Antiretroviral Treatment
Fixed Dose Combination a Simplified Approach to Pediatric Antiretroviral Treatment Dr. David Pugatch Clinton Foundation Phnom Penh, Cambodia February, 2007 Lecture Goals To introduce and define fixed dose
More informationTRUVADA for a Pre-exposure Prophylaxis (PrEP) Indication. Training Guide for Healthcare Providers
TRUVADA for a Pre-exposure Prophylaxis (PrEP) Indication Training Guide for Healthcare Providers About TRUVADA for a PrEP indication to reduce the risk of sexually acquired HIV-1 infection in high-risk
More informationDiagnosis and Treatment of Tuberculosis, 2011
Diagnosis of TB Diagnosis and Treatment of Tuberculosis, 2011 Alfred Lardizabal, MD NJMS Global Tuberculosis Institute Diagnosis of TB, 2011 Diagnosis follows Suspicion When should we Think TB? Who is
More informationStructured Treatment Interruption in HIV Positive Patients. Leah Jackson, BScPhm Pharmacy Resident HIV Rotation January 23, 2007
Structured Treatment Interruption in HIV Positive Patients Leah Jackson, BScPhm Pharmacy Resident HIV Rotation January 23, 2007 Objectives To become re-acquainted with the basics of HAART for HIV infection
More informationHIV and AIDS. Shan Nanji
HIV and AIDS Shan Nanji HIV 2 Description: Enveloped Positive Sense HIV 3 Structural Genes: Cleavage of gp160 leads to formation of ENV: Gp120: attachment to host CD4 T Cell Gp41: GAG (p24) Capsid protein
More informationMEDICATION GUIDE Abacavir, Lamivudine and Zidovudine Tablets (a-bak-a-vir, la-miv-ue-deen, zye-doe-vue-deen)
MEDICATION GUIDE Abacavir, Lamivudine and Zidovudine Tablets (a-bak-a-vir, la-miv-ue-deen, zye-doe-vue-deen) What is the most important information I should know about abacavir, lamivudine and zidovudine
More informationTOXICITY, TOLERABILITY, AND ADHERENCE TO THERAPY
SAFETY AND TOLERABILITY OF CURRENTLY AVAILABLE ANTIRETROVIRAL AGENTS * Esteban Martinez, MD, PhD ABSTRACT Safety and tolerability are important factors to consider when instituting or modifying therapy
More informationModule 6: ARVs in Children
Module 6: ARVs in Children Module Objectives To review the use of ARVs in children and their impact on disease progression To provide nurses with a general understanding of the differences in ARV use in
More informationMedical monitoring: Clinical monitoring and laboratory tests
medical monitoring: clincial monitoring and laboratory tests: 1 medical monitoring: clinical monitoring and laboratory tests Medical monitoring: Clinical monitoring and laboratory tests Aims This section
More informationHIV Treatment Update. Awewura Kwara, MD, MPH&TM Associate Professor of Medicine and Infectious Diseases Brown University
HIV Treatment Update Awewura Kwara, MD, MPH&TM Associate Professor of Medicine and Infectious Diseases Brown University Outline Rationale for highly active antiretroviral therapy (HAART) When to start
More informationHIV basics. Katya Calvo Medical Director of Antimicrobial Stewardship
HIV basics Katya Calvo Medical Director of Antimicrobial Stewardship Learning Objectives 1. Review of HIV epidemiology worldwide and locally 2. Review of recommendations on whom to screen 3. Work up of
More informationHIGHLIGHTS OF PRESCRIBING INFORMATION
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use VIREAD safely and effectively. See full prescribing information for VIREAD. VIREAD (tenofovir disoproxil
More informationPaediatric ART: eligibility criteria and first line regimens. (revised) Dave le Roux 13 August 2016
Paediatric ART: eligibility criteria and first line regimens (revised) Dave le Roux 13 August 2016 Outline Eligibility criteria for starting ART Evolving evidence for earlier ART W Cape, National, WHO
More informationREVIEW No Assessment of safety a. Have all relevant studies on safety been included Yes X No (if no, please provide reference and information)
Expert peer review on application for addition of fixed dose combination formulations of antiretroviral medications in the EML (Adults) REVIEW No. 2 Abacavir + lamivudine (ABC+ 3TC) Tablet (dispersible):
More informationIntroduction: WHO recommends that criteria for starting ART be defined in national protocols and that these
ISSN: 0975-766X Available Online through Research Article www.ijptonline.com HEALTH PROFILE OF HIV POSITIVE INDIVIDUALS AT ANTI RETROVIRAL TREATMENT CENTRE, KADAPA DISTRICT Dr.K.Chandra Sekhar *, Dr. K.J.Kishore
More informationTreatment of Latent TB Infection (LTBI)
Treatment of Latent TB Infection (LTBI) Mahesh C. Patel, MD June 14, 2017 2014 MFMER slide-1 Mahesh C. Patel, MD Associate Professor Treatment of LTBI Department of Internal Medicine, Division of Infectious
More informationMedscape's Antiretroviral Pocket Guide for the Treatment of HIV Infection
Table 3. Characteristics of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) Generic Name (Abbreviation) / Trade Name Abacavir (ABC) / Ziagen Trizivir with ZDV + 3TC Epzicom with 3TC Didanosine (ddi)
More informationLTBI Videos-Treatment
LTBI Videos-Treatment This program is presented by the Global Tuberculosis Institute and is based on recommendations from the Centers for Disease Control and Prevention. This is the third in a series of
More informationClinical Characteristics and The Selection of Initial ARV Regimen Therapy for HIV-Infected Patients in VCT-CST RSUP Sanglah, Denpasar
Clinical Characteristics and The Selection of Initial ARV Regimen Therapy for HIV-Infected Patients in VCT-CST RSUP Sanglah, Denpasar I G. A. Putu Candradewi, I Ketut Agus Somia Departement of Internal
More informationSA HIV Clinicians Society Adult ART guidelines
SA HIV Clinicians Society Adult ART guidelines In draft format Graeme Meintjes (on behalf of the guidelines committee) Selected topics When to start ART First-line Second-line Third-line Patients with
More informationVOICE Screening Part 1 Visit. Operational Walkthrough Johannesburg, South Africa November 2008
VOICE Screening Part 1 Visit Operational Walkthrough Johannesburg, South Africa November 2008 Protocol Requirements Administrative, Behavioral, and Regulatory Procedures Informed consent for screening
More informationMonitoring During Antiretroviral Therapy: Issues and Concerns. Subhasish Kamal Guha
Monitoring During Antiretroviral Therapy: Issues and Concerns Subhasish Kamal Guha With the rapid scale up of antiretroviral treatment programme in the public sector associated with availability of a large
More informationHIV Treatment. Why do I need to know about HIV treatment?
HIV Treatment Why do I need to know about HIV treatment? As a person living with HIV, you have to decide which HIV treatment is right for you, using the best information available. The more informed you
More informationAntiretroviral treatment outcomes after the introduction of tenofovir in the public-sector in South Africa
Antiretroviral treatment outcomes after the introduction of tenofovir in the public-sector in South Africa Alana T Brennan, Kate Shearer, Mhairi Maskew, Prudence Ive, Ian Sanne, Matthew P Fox Health Economics
More informationLactic Acidosis and Ascending Neuromuscular Syndrome. Mina Hosseinipour, M.D, MPH. University of North Carolina Project, Lilongwe Malawi
Lactic Acidosis and Ascending Neuromuscular Syndrome Mina Hosseinipour, M.D, MPH. University of North Carolina Project, Lilongwe Malawi Introduction ART is rapidly scaling up in resource poor countries
More informationTreatment of respiratory virus infection Influenza A & B Respiratory Syncytial Virus (RSV)
Treatment of respiratory virus infection Influenza A & B Respiratory Syncytial Virus (RSV) Amantadine and Rimantadine Use is limited to Influenza A infection. Very effective in preventing infection if
More informationSupplementary Methods. HIV Synthesis Transmission V1. Model details
Effect on transmission of HIV-1 resistance of timing of implementation of viral load monitoring to determine switches from first to second line antiretroviral regimens in resource-limited settings. Supplementary
More informationAdult Guidelines. Sipho Dlamini. Division of Infectious Diseases & HIV Medicine University of Cape Town Groote Schuur Hospital
Adult Guidelines Sipho Dlamini Division of Infectious Diseases & HIV Medicine University of Cape Town Groote Schuur Hospital Cape Town CME 3 rd June 2017 Sports Science Institute, Newlands Outline of talk
More informationYear 2002 Paper two: Questions supplied by Jo 1
Year 2002 Paper two: Questions supplied by Jo 1 Question 9 A 37 year old man with known human immunodeficiency virus (HIV) infection for 10 years presents with severe renal colic for which he has no prior
More informationTORONTO GENERAL HOSPITAL HIV AMBULATORY CARE ROTATION
TGH - ambulatory rotation page 1 of 5 TORONTO GENERAL HOSPITAL HIV AMBULATORY CARE ROTATION SITE: Immunodeficiency Clinic, Toronto General Hospital, University Health Network Location: 13 th floor, Norman
More informationConcomitant antiretroviral therapy : Avifanz must be given in combination with other antiretroviral medications.
Avifanz Tablet Description Avifanz is the brand name for Efavirenz. Efavirenz, a synthetic antiretroviral agent, is a non-nucleoside reverse transcriptase inhibitor. While Efavirenz is pharmacologically
More informationBHIVA Clinical Audit. Management of patients who switch therapy; re-audit of patients starting therapy from naïve
BHIVA Clinical Audit Management of patients who switch therapy; re-audit of patients starting therapy from naïve 1 2004-5 5 audit projects Reporting now:! Survey and case note review of patients switching
More informationSection 4: Side effects of ARVs. 4.1 Introduction. 4.2 Aims for this section
Section : Side effects of ARVs Section : Side effects of ARVs Regular blood tests will check for some side effects. If you have any difficulties make sure your doctor takes these seriously... Nausea and
More informationEFAVIRENZ ASSOCIATED STEVENS-JOHNSON SYNDROME
EFAVIRENZ ASSOCIATED STEVENS-JOHNSON SYNDROME To the Editor: Persons with human immunodeficiency virus (HIV) infection are highly susceptible to adverse dermatological reactions to specific medications
More informationFurther publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for
Further publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for South-East Asia, World Health House, Indraprastha Estate,
More informationGUIDELINES FOR THE USE OF ANTIRETROVIRAL THERAPY IN PAPUA NEW GUINEA
GUIDELINES FOR THE USE OF ANTIRETROVIRAL THERAPY IN PAPUA NEW GUINEA These guidelines were prepared for the Papua New Guinea National AIDS Council and the Papua New Guinea National Department of Health.
More informationTreatment of MDR-TB in high HIV- prevalence settings. Hind Satti, M.D. PIH-Lesotho October 20, 2008
Treatment of MDR-TB in high HIV- prevalence settings Hind Satti, M.D. PIH-Lesotho October 20, 2008 Early outcomes of MDR-TB treatment Retrospective cohort analysis Registered between July 21, 2007 and
More informationTHE STAGING AND MEDICATION OF HIV INFECTION
Supplement A: WHO CLINICAL STAGING THE STAGING AND MEDICATION OF HIV INFECTION Clinical Stage 1 Clinical Stage 2 Clinical Stage 3 Clinical Stage 4 Asymptomatic Persistent generalized lymphadenopathy Moderate
More informationInt. J. Pharm. Sci. Rev. Res., 26(2), May Jun 2014; Article No. 15, Pages: 79-83
Research Article Comparing Efficacy and Safety of Stavudine Plus Lamivudine Versus Zidovudine Plus Lamivudine in Combination with Nevirapine in HIV Infected Individuals Receiving Antiretroviral Therapy
More informationMedical PCCN. AACN Progressive Critical Care Nursing.
Medical PCCN AACN Progressive Critical Care Nursing http://killexams.com/pass4sure/exam-detail/pccn Question: 83 What would be identified on the arterial blood gas results as a reflection of acute respiratory
More informationFigure S1: Overview of PMTCT Options A and B. Prevention of Mother to Child HIV Transmission (PMTCT)
Figure S1: Overview of PMTCT Options A and B Prevention of Mother to Child HIV Transmission (PMTCT) Option A: combined Antiretroviral therapy (ART) for all women meeting WHO 2010 criteria for initiation
More informationReasons for Anti-Retroviral Regimen Changes in HIV/AIDS patients of Ayder Referral Hospital ART clinic, Mekelle, Ethiopia.
Reasons for Anti-Retroviral Regimen Changes in HIV/AIDS patients of Ayder Referral Hospital ART clinic, Mekelle, Ethiopia. LEMLEM GEBREMEDHIN *, AMANUEL BIRHANE 2, 2 Pharmacology and Toxicology course
More informationElements for a public summary
VI.2 Elements for a public summary VI.2.1 Overview of disease epidemiology Nevirapine is used for antiretroviral combination therapy of Human Immunodeficiency Virus (HIV) infection. Human immunodeficiency
More informationTocilizumab (Actemra )
Tocilizumab (Actemra ) How does it works? Actemra is a biologic medicine that helps keep the immune system from attacking healthy tissues in the body by blocking the protein IL-6 (interleukin-6). Actemra
More information3 East and Central African Journal of Pharmaceutical Sciences Vol. 16 (2013) 3-12
3 East and Central African Journal of Pharmaceutical Sciences Vol. 16 (2013) 3-12 Detection and Management of Adverse Drug Reactions Related to Antiretroviral Drugs among HIV/AIDS Patients in Kiambu Sub-County,
More informationThe Hospitalized HIV+ Patient
The Hospitalized HIV+ Patient Danny Toub MD dannyt@srheathcenters.org October 8, 2012 Santa Rosa Family Medicine Residency List 3 ways of risk-stratifying known or suspected HIV+ inpatients Perform differential
More informationHIGHLIGHTS OF PRESCRIBING INFORMATION
HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use VIREAD safely and effectively. See full prescribing information for VIREAD. VIREAD (tenofovir disoproxil
More informationFurther publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for
Further publications can be obtained from the HIV/AIDS Unit, Department of Communicable Diseases, World Health Organization, Regional Office for South-East Asia, World Health House, Indraprastha Estate,
More informationReaching HIV-1 Treatment Decisions Without a Patient s Medical Records
Transcript Details This is a transcript of an educational program accessible on the ReachMD network. Details about the program and additional media formats for the program are accessible by visiting: https://reachmd.com/programs/medical-industry-feature/reaching-hiv-1-treatment-decisions-withoutpatients-medical-records/10466/
More informationImportant Safety Information About Emtricitabine/Tenofovir Disoproxil Fumarate 200 mg/300 mg for HIV-1 Pre-exposure Prophylaxis (PrEP)
Important Safety Information About Emtricitabine/Tenofovir Disoproxil Fumarate 200 mg/300 mg for HIV-1 Pre-exposure Prophylaxis (PrEP) For Healthcare Providers About Emtricitabine/Tenofovir Disoproxil
More informationObjectives. 3HP and Flu Syndrome What is the Underlying Mechanism? Case #1 3/23/2016. Christina T. Fiske, MD MPH March 30, 2016
Objectives 3HP and Flu Syndrome What is the Underlying Mechanism? Christina T. Fiske, MD MPH March 30, 2016 Illustrate the side effect of 3HP flu like syndrome after its initiation to raise awareness in
More informationClinical skills building - HIV drug resistance
Clinical skills building - HIV drug resistance Richard Lessells Clinical case 44-year old HIV-positive male HIV diagnosis 2010 Pre-treatment CD4+ count not known Initiated first-line ART (TDF/FTC/EFV)
More informationABACAVIR HYPERSENSITIVITY REACTION
ABACAVIR HYPERSENSITIVITY REACTION Abacavir is a component of Ziagen, Trizivir, Kivexa and Triumeq Triumeq is subject to additional monitoring UK/HIV/0042/15(3) October 2016 Slide Contents CONTENT SLIDES
More informationCASE-BASED SMALL GROUP DISCUSSION
MHD I, Session 11, Student Copy Page 1 CASE-BASED SMALL GROUP DISCUSSION MHD I SESSION 11 Renal Block Acid- Base Disorders November 7, 2016 MHD I, Session 11, Student Copy Page 2 Case #1 Cc: I have had
More information