For the quantitative determination of human chorionic gonadotropin (hcg) concentration in human serum.

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1 1. IDENTIFICATION Product name: Human Chorionic Gonadotropin hcg (CATALOG No. F1027) Product Use: Supplier: For the quantitative determination of human chorionic gonadotropin (hcg) concentration in human serum. POINTE SCIENTIFIC INC Research Drive Canton, Michigan Ph: Fax: Emergency: Pointe Scientific, Inc. Tel HAZARD(S) IDENTIFICATION Conjugate Reagent: Reference Standards: Skin Corrosion/Irritation (Category 2) H315: Causes skin irritation P264: Wash skin thoroughly after handling.

2 Zero Buffer: TMB Reagent: Pictogram: Not required. Signal Word: Not required. Stop Solution: Skin corrosion/irritation (Category 1) Serious eye damage/eye irritation (Category 1) Sensitization, respiratory (Category 1) Specific target organ toxicity, single exposure; respiratory system (Category 1) Specific target organ toxicity, repeat exposure; respiratory system and teeth (Category 1) H314: Causes severe skin burns and eye damage H318: Causes serious eye damage H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled H370: Causes damage to organs H372: Causes damage to organs through prolonged or repeated exposure Signal Word: Danger P260: Do not breathe dust/fume/gas/mist/vapors/spray. P264: Wash skin thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P285: In case of inadequate ventilation wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P314: Get medical advice/attention if you feel unwell. P301 + P330 + P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353: IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304 + P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

3 P307 + P311: IF exposed: call a POISON CENTER or doctor/physician. P342 + P311: IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. P404: Store in a closed container. P501: Dispose of contents to sewer system, if in accordance with local regulations. 3. COMPOSITION / INFORMATION ON INGREDIENTS Conjugate Reagent: Proclin 300 (CAS # ) 0.5% Reference Standards: Proclin 300 (CAS # ) 1% Zero Buffer: Proclin 300 (CAS # ) 0.5% TMB Reagent: 3,3,5,5 -Tetramethylbenzidin (CAS # ) 0.05% Stop Solution: Hydrochloric Acid (CAS # ) 3.08% 4. FIRST AID MEASURES SKIN: EYES: ORAL: INHALATION: In case of contact, immediately take of contaminated clothing and/or shoes. Wash off with soap and plenty of water. Consult a physician. Rinse thoroughly with plenty of water for at least 15 minutes and get medical attention. Continue rinsing eyes during transport to a medical facility. Do not induce vomiting. Rinse mouth with water. Consult a physician. If inhaled move victim to fresh air. If not breathing give artificial respiration. If breathing is difficult give oxygen, and call physician. 5. FIRE-FIGHTING MEASURES Flammable: Extinguishing media: Flash point: Upper flammable limit: Lower flammable limit: Auto ignition temperature: Hazardous combustion products: NO As appropriate for fire in surrounding materials. Use water spray, alcohol resistant foam, dry chemical or carbon dioxide. Carbon oxides, nitrogen oxides, Sulphur oxides, hydrogen chloride gas Explosion data Sensitivity to mechanical impact: Sensitivity to static discharge: Unusual fire and explosion hazards: No Data 6. ACCIDENTAL RELEASE MEASURES Local exhaust: Protective clothing: Protective gloves: Eye protection: Respiratory protection: Leak and spill procedure: Not Required Lab Coat Rubber/Latex Safety glasses Required if inadequate ventilation. Soak up with absorbent material and dispose of to a waste disposal plant. Prevent entry into water system. 7. HANDLING AND STORAGE Handling: Shipping regulations: Normal precautions for handling chemicals must be observed. Store between +2 C and +8 C Not regulated 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Local exhaust: Protective clothing: Protective gloves: Eye protection: Respiratory protection: Other precautions: Not Required Lab Coat Rubber/Latex Safety glasses None normally required. Avoid contact and inhalation, do not get in eyes, on skin or clothing. Do not pipet by mouth. Wash contaminated clothing before reuse.

4 9. PHYSICAL AND CHEMICAL PROPERTIES Kit Component / Chemical Standard/Conjugate/ Sample Diluent TMB Reagent (3,3,5,5 - Tetramethylbenzidin) Stop Solution (1 N HCl) (ProClin 300) (a) Appearance: Form: Liquid Solid Liquid Color Light yellow Clear to yellow Clear (b) Odour odourless no data available pungent odour (c) Odour threshold no data available no data available no data available (d) ph 4.1 at 100 g/l (e) Melting point/freezing -40 C (-40 F) C 0 C point (f) Initial boiling point and 189 C (372 F) C 100 C boiling range (g) Flash point 118 C (244 F) no data available no data available (h) Evaporation rate no data available no data available >1 (i) Flammability (solid, gas) no data available no data available no data available (j) Upper/lower flammability no data available no data available no data available or explosive limits (k) Vapor pressure no data available no data available 4.0 atm (l) Vapor density no data available no data available no data available (m) Relative density 1.03 g/cm3 no data available no data available (n) Solubility(ies) water soluble insoluble water soluble (o) Partition coefficient: n- no data available no data available no data available octanol/water (p) Auto-ignition no data available no data available no data available temperature (q) Decomposition no data available no data available no data available temperature (r) Viscosity 58.8 mpa.s at 25 C no data available no data available (77 F) (s) Explosive properties no data available no data available no data available (t) Oxidising properties no data available not an oxidizer no data available 10. STABILITY AND REACTIVITY Stable: Yes Hazardous polymerization: Will not occur. Incompatibility with other substances: Avoid strong oxidizing agents, reducing agents, amines mercaptans. Hazardous decomposition products: 11. TOXICOLOGICAL INFORMATION ROUTE OF ENTRY/EXPOSURE SKIN CONTACT: [x] EYE CONTACT: [x] INHALATION: [x] INGESTION: [x] SKIN ABSORPTION [x] Effects of acute exposure: SKIN CONTACT: May cause irritation. EYE CONTACT: May cause irritation. INGESTION: May be harmful if ingested. INHALATION: May cause irritation to mucous membranes and upper respiratory tract. Effects of chronic exposure: No data available. SENSITIZATION TO PRODUCT: SYNERGISTIC PRODUCTS: LD50: MOPSO: 12. ECOLOGICAL INFORMATION Water Hazard Class: Data not yet available

5 13. DISPOSAL CONSIDERATIONS Waste disposal: Dispose of in accordance with local official environmental regulations 14. TRANSPORT INFORMATION Shipping information: Not regulated 15. REGULATORY INFORMATION Not applicable. 16. OTHER INFORMATION The information herein is believed to be correct as of the date hereof but is provided without warranty of any kind. The recipient of our products is responsible for observing any laws and guidelines applicable. Document number: SDS-F1027 Rev. 7/15

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