Animal testing versus calculation method

Size: px
Start display at page:

Download "Animal testing versus calculation method"

Transcription

1 Animal testing versus calculation method Dr. Tamara Coja, MSc Toxicology Institute for Plant Protection Products, Department for Toxicology Interzonal workshop Harmonisation of risk assessment in section toxicology Vienna, June 2015 Austrian Agency for Health and Food Safety

2 Outline European Legislations and animal testing Data requirements for testing of PPPs according to Regulation (EU) No 284/2013 Examples: I ) Necessity or no-necessity of acute inhalation toxicity study II) Vertebrate study versus calculation method 2

3 European Legislations and animal testing 3

4 Animal testing Directive 2010/63/EU (Legislation for the protection of animals used for scientific purposes), Article 47: 1. The Commission and the Member States shall contribute to the development and validation of alternative approaches which could provide the same or higher levels of information as those obtained in procedures using animals, but which do not involve the use of animals or use fewer animals (). 4. Member States shall, at national level, ensure the promotion of alternative approaches and the dissemination of information thereon. 4

5 REACH Data sharing Companies must share information on their hazardous properties and jointly submit this hazard information to ECHA Alternative methods and approaches Companies can use existing animal studies, conducted before REACH. They can also predict the properties of substances by read-across approach 5

6 REACH ECHA testing proposals: QSAR Toolbox: 6

7 Regulation (EC) No 1223/2009 The Cosmetics Regulation prohibits the placing on the market of cosmetic products, or products containing ingredients, which have been tested on animals to meet the requirements of that regulation using a method other than a validated alternative method 7

8 Regulation (EC) No 1272/2008 (27) The classification and labelling criteria set out in this Regulation should take the utmost account of promoting alternative methods for the assessment of hazards of substances and mixtures and of the obligation to generate information on intrinsic properties by means other than tests on animals within the meaning of Directive 86/609/EEC (now: Directive 2010/63/EU) as laid down in Regulation (EC) No 1907/

9 Article 62 of Regulation (EC) No 1107/2009 Article 62 (Sharing of tests and studies involving vertebrate animals): 1. Testing on vertebrate animals for the purposes of this Regulation shall be undertaken only where no other methods are available. Duplication of tests and studies on vertebrates undertaken for the purposes of this Regulation shall be avoided in accordance with paragraphs 2 to Member States shall not accept duplication of tests and studies on vertebrate animals or those initiated where conventional methods (Remark: calculation method is meant) described in Annex II to Directive 1999/45/EC could reasonably have been used, in support of applications for authorisations. 9

10 Data requirements PPP Regulation (EU) No 284/

11 Data requirements PPP - Regulation (EU) No 284/ Tests on vertebrate animals shall be undertaken only where no other validated methods are available. Alternative methods: in vitro methods and in silico methods; reduction and refinement methods for in vivo testing (3Rs) 11

12 Data requirements PPP - Regulation (EU) No 284/2013 Acute oral toxicity A test for acute oral toxicity shall be carried out, unless the applicant can justify an alternative approach under Regulation (EC) No 1272/2008 Acute dermal toxicity A test for dermal toxicity shall be carried out on a case by case basis, unless the applicant can justify an alternative approach under Regulation (EC) No 1272/

13 Data requirements PPP - Regulation (EU) No 284/2013 Acute inhalation toxicity The study shall provide the inhalation toxicity to rats of the plant protection product or of the smoke it generates The study shall be carried out where the plant protection product: (a) is a gas or liquified gas; (b) is a smoke generating plant protection product or fumigant; (c) is used with fogging/misting equipment; (d) is a vapour releasing plant protection product; (e) is supplied in an aerosol dispenser; 13

14 Data requirements PPP - Regulation (EU) No 284/2013 (f) is in a form of a powder or granules containing a significant proportion of particles of diameter < 50 µm (> 1 % on a weight basis); (g) is to be applied from aircraft in cases where inhalation exposure is relevant; (h) contains an active substance with a vapour pressure > Pa and is to be used in enclosed spaces such as warehouses or glasshouses; (i) is to be applied by spraying. A study shall not be required if the applicant can justify an alternative approach under Regulation (EC) No 1272/2008, where applicable 14

15 Data requirements PPP - Regulation (EU) No 284/2013 Skin irritation The skin irritancy of the plant protection product shall be reported based on the tiered approach, unless the applicant can justify an alternative approach under Regulation (EC) No 1272/2008. First: weight of evidence if study necessary Tiered approach: (1) the assessment of dermal corrosivity using a validated in vitro test method; (2) the assessment of dermal irritation using a validated in vitro test method (such as human reconstituted skin models); (3) an initial in vivo dermal irritation study using one animal, and where no adverse effects are noted; (4) confirmatory testing using one or two additional animals. 15

16 Data requirements PPP - Regulation (EU) No 284/2013 Eye irritation Eye irritation tests shall be provided, unless it is likely that severe effects on the eyes may be produced or the applicant can justify an alternative approach under Regulation (EC) No 1272/2008. First: weight of evidence if study necessary Tiered approach: (1) the use of an in vitro dermal irritation/corrosion test to predict eye irritation/corrosion; (2) the performance of a validated or accepted in vitro eye irritation study to identify severe eye irritants/ corrosives (such as BCOP, ICE, IRE, HET-CAM), and where negative results are obtained; 16

17 Data requirements PPP - Regulation (EU) No 284/2013 Eye irritation (3) the assessment of eye irritation using an available, in vitro test method validated for plant protection products for identification of nonirritants or irritants, and when not available; (4) an initial in vivo eye irritation study using one animal, and where no adverse effects are noted; (5) confirmatory testing using one or two additional animals. 17

18 Data requirements PPP - Regulation (EU) No 284/2013 Skin sensitisation The skin sensitisation test shall be carried out unless the active substances or co-formulants are known to have sensitising properties or the applicant can justify an alternative approach under Regulation (EC) No 1272/

19 Data requirements PPP - Regulation (EU) No 284/2013 Prerequisite for applicability of calculation method for estimation of acute toxicity, irritation and sensitisation: toxicological properties of all components shall be provided or reliably predicted by a validated method 19

20 Available OECD Guidelines in vitro Skin corrosion/irritation (latest updates): 26 Sep 2014: Test No. 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (Rhe) Test Method 26 July 2013: Test No. 430: In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test Method (TER) 26 July 2013: Test No. 431: In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method 26 July 2013: Test No. 439: In Vitro Skin Irritation - Reconstructed Human Epidermis Test Method 20

21 Available OECD Guidelines in vitro Eye damage/irritation (latest updates): 26 July 2013: Test No. 437: Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 26 July 2013: Test No. 438: Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage 02 Oct 2012: Test No. 460: Fluorescein Leakage Test Method for Identifying Ocular Corrosives and Severe Irritants 21

22 Available OECD Guidelines in vitro Skin sensitisation (new): 05 Feb 2015:Test No. 442C: In Chemico Skin Sensitisation 05 Feb 2015:Test No. 442D: In Vitro Skin Sensitisation 22

23 Regulatory real life examples Acute inhalation toxicity 23

24 Acute inhalation toxicity What is meant in Regulation (EC) 284/2013 by: acute inhalation toxicity study is necessary if PPP is to be applied by spraying? ( Old Commission Regulation (EU) No 545/2011: if PPP is to be applied in a manner which generates a significant proportion of particles or droplets of diameter < 50 µm (> 1 % on a weight basis) ). Particle size in the acute inhalation toxicity study 1 4 µm Particle size for spraying in e.g grapes (fine particles) recommended at 350 µm and should not be < 125 µm Particles > 100 µm have high settling velocity, so exposure unlikely to occur 24

25 Acute inhalation toxicity 1272/2008: The ECHA guidance document on the application of CLP criteria (pages , June 2015) states: () The use of highly respirable dusts and mists is ideal to fully investigate the potential inhalation hazard of the substance. However, it is acknowledged that these exposures may not necessarily reflect realistic conditions. For instance, solid materials are often micronised to a highly respirable form for testing, but in practice exposures will be to a dust of much lower respirability.() In such situations, specific problems may arise with respect to classification and labelling, as these substances are tested in a form (i.e. specific particle size distribution) that is different from all the forms in which these substances are placed on the market and in which they can reasonably be expected to be used (). 25

26 Acute inhalation toxicity So, trigger for inhalation testing is exposure-related A philosophical question: if no acute inhalation study is necessary according to data requirements and no exposure expected, than we are not allowed to classify based on properties of active or coformulants, right? 26

27 Acute inhalation toxicity C&L of active XY T, R23; Toxic by inhalation Acute Tox 2, H330; Fatal if inhaled Formulatio n type Content of active XY (%) in PPP WG 70 Grapes, spraying GAP Remark % active XY in spray dilution PPP nearly dust free, no attrition < 0.1% particles of respirable size (< 10 µm) < 0.1% particles < 50 µm 0.05% to 0.375% zrms decided not to classify for acute inhalation toxicity and received mostly disagreements by cms 27

28 Regulatory real life examples Unnecessary vertebrate studies versus calculation method 28

29 Vertebrate studies versus calculation method Component in PPP C&L Content (%) in PPP Formulation type GAP Remarks Active substance Formulant 1 Formulant 2 Xn, R22/20 H302 H332 R41 H318 Well-known food additive 15 SG, nearly dust free Field crops (cereals, etc..) 82 LD50 oral > 5000 No skin irritant No skin sensitiser No data on acute dermal and acute inhalation toxicity

30 Vertebrate studies versus calculation method zrms accepted all six submitted vertebrate studies Calculation method would lead us solely to: R41 / H318 Studies showed: R41 / H318 and R22 / H302 What would we miss if we loose R22 / H302? 1) P270: Do not eat, drink or smoke when using the product (GAP anyhow?) optional for professional users according to Guidance on Labelling and Packing in accordance with Regulation (EC) No 1272/2008 2) P264 Wash thoroughly after handling (if hands are meant, GAP anyhow?) - optional 3) P301 + P312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell - optional 4) P330 Rinse mouth - optional 30

31 Food for thoughts? Acute oral toxicity study calculation method in most cases easily applicable Acute dermal toxicity study waiving easily applicable (results of acute oral study and skin irritation) Acute inhalation toxicity study do we need it if there is no realistic exposure? Skin and eye irritation study calculation method applicable case by case, certainly applicable when co-formulants classified Skin sensitisation probably most difficult to predict, unless information on known sensitiser available 31

32 Food for thoughts? How much information do we loose if we mistakenly not classify for acute toxicity, irritation and sensitisation? What about risk mitigation measures in uncertain cases (e.g. wear eye protection if calculation method uncertain or not sufficient data on co-formulants) instead of vertebrate study? Appeal to the Member States and the industry: let us think twice before we ask for /conduct an unnecessary animal study 32

33 To start the expert discussions CIRCABC expert forum established for exchange of knowledge, questions, doubts (Member States) CIRCABC PPP Zonal Newsgroups Toxicology and Operator & Bystander Safety Let`s start live it! 33

Ian Indans Regulatory scientist Chemicals Regulation Directorate (CRD)

Ian Indans Regulatory scientist Chemicals Regulation Directorate (CRD) Health and Safety Executive Ian Indans Regulatory scientist Chemicals Regulation Directorate (CRD) Health and Safety Executive Acute Inhalation Toxicity testing; The 3Rs, Current needs and Future Prospects

More information

Official Journal of the European Union

Official Journal of the European Union 1.6.2016 L 144/27 COMMISSION REGULATION (EU) 2016/863 of 31 May 2016 amending Annexes VII and VIII to Regulation (EC) No 1907/2006 of the European Parliament and of the Council on the Registration, Evaluation,

More information

: FLUVASTATIN SODIUM CRS

: FLUVASTATIN SODIUM CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 27/11/2009 Version: 3.0 SECTION 1: Identification of the substance/mixture

More information

: PANTOPRAZOLE SODIUM SESQUIHYDRATE CRS

: PANTOPRAZOLE SODIUM SESQUIHYDRATE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 25/11/2009 Version: 6.0 SECTION 1: Identification of the substance/mixture

More information

: SALBUTAMOL SULFATE CRS

: SALBUTAMOL SULFATE CRS Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 04/02/2010 Version: 6.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product

More information

: MEPROBAMATE CRS. Safety Data Sheet Safety Data Sheet in accordance with Regulation (EC) No. 1907/2006, as amended.

: MEPROBAMATE CRS. Safety Data Sheet Safety Data Sheet in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 16/12/2009 Version: 5.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product

More information

: THIOCTIC ACID CONTAINING IMPURITY B CRS

: THIOCTIC ACID CONTAINING IMPURITY B CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 17/12/2009 Version: 4.0 SECTION 1: Identification of the substance/mixture

More information

: BENZYL ALCOHOL CRS

: BENZYL ALCOHOL CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 04/02/2010 Version: 5.0 SECTION 1: Identification of the substance/mixture

More information

Safety Data Sheet - Version 5.0 Preparation Date 11/10/2016 Latest Revision Date (If Revised) SDS Expiry Date 11/9/2019

Safety Data Sheet - Version 5.0 Preparation Date 11/10/2016 Latest Revision Date (If Revised) SDS Expiry Date 11/9/2019 Safety Data Sheet - Version 5.0 Preparation Date 11/10/2016 Latest Revision Date (If Revised) SDS Expiry Date 11/9/2019 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product

More information

NK Seaweed+Humic Acid Liquid

NK Seaweed+Humic Acid Liquid 8011 Material Safety Data Sheet NK 20-0-10+Seaweed+Humic Acid Liquid Issue Date: 16-Feb-16 Revision Date: 16-Feb-16 Revision Number: 1 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND COMPANY/UNDERTAKING

More information

: TRIAMCINOLONE HEXACETONIDE CRS

: TRIAMCINOLONE HEXACETONIDE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 14/12/2009 Version: 5.0 SECTION 1: Identification of the substance/mixture

More information

: SALBUTAMOL IMPURITY B CRS

: SALBUTAMOL IMPURITY B CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 30/08/2013 Revision date: 30/08/2013 Supersedes: 27/06/2013 Version: 4.1 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET Break-Free CLP-E

SAFETY DATA SHEET Break-Free CLP-E Break-Free CLP-E Page 1 of 5 SAFETY DATA SHEET Break-Free CLP-E SECTION 1: Identification of the substance/mixture and of the company/undertaking Date issued 18.12.2012 1.1. Product identifier Product

More information

1 of 27 11/20/2012 9:07 AM

1 of 27 11/20/2012 9:07 AM 1 of 27 11/20/2012 9:07 AM A to Z Index En español Contact Us FAQs About OSHA OSHA Newsletter RSS Feeds Print This Page Text Size Was this page helpful? What's New Offices Home Workers Regulations Enforcement

More information

SAFETY DATA SHEET In accordance with REACH Regulation EC No.1907/2006

SAFETY DATA SHEET In accordance with REACH Regulation EC No.1907/2006 Page 1 ( 8 ) (13/05/2015) Section 1. Identification of the substance or the mixture and of the supplier 1.1 Product Identifier Product identifier: Other identifiers: (Contains:ALPHA-ISOMETHYL IONONE, METHYL

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 8 (06/03/205 Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers: (Contains:Piperonal None.2 Relevant identified

More information

Sodium Dichromate (VI) Anhydrous

Sodium Dichromate (VI) Anhydrous Revision date 08-04-2016 1.1 Product identifier Sodium Dichromate (VI) Section 1: Identification of the substance/ mixture and of the company/ undertaking. Product name Other names Sodium Dichromate (VI)

More information

SECTION 1: Identification of the substance/mixture and of the company/undertaking

SECTION 1: Identification of the substance/mixture and of the company/undertaking Page 1 of 10 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product Identifier Trade name / designation: Additional information: The substance does not require registration

More information

RUTIN (TRIHYDRATE) FOR BIOCHEMISTRY MSDS. CAS No: MSDS MATERIAL SAFETY DATA SHEET (MSDS)

RUTIN (TRIHYDRATE) FOR BIOCHEMISTRY MSDS. CAS No: MSDS MATERIAL SAFETY DATA SHEET (MSDS) RUTIN (TRIHYDRATE) FOR BIOCHEMISTRY MSDS CAS No: 3420-18-4 MSDS MATERIAL SAFETY DATA SHEET (MSDS) SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier

More information

Copper (II) Chloride 2-Water

Copper (II) Chloride 2-Water Revision date 08-04-2016 1.1 Product identifier Copper (II) Chloride 2-Water Section 1: Identification of the substance/ mixture and of the company/ undertaking. Product name Other names Copper (II) Chloride

More information

Safety Data Sheet according to COMMISSION REGULATION (EU) 2015/830 (REACH)

Safety Data Sheet according to COMMISSION REGULATION (EU) 2015/830 (REACH) Safety Data Sheet according to COMMISSION REGULATION (EU) 2015/830 (REACH) Validity Print date Last revision Version 01 IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING EU, CH 02.01.2013

More information

Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) Fax: + 44 (0)

Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) Fax: + 44 (0) SECTION 1: COMPANY AND PRODUCT IDENTIFICATION Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) 1302 836800 Fax: + 44 (0) 1302 836899 Product Name: Description:

More information

SAFETY DATA SHEET. Product: Chamomile Oil, Roman (Anthemis nobilis) EOS70

SAFETY DATA SHEET. Product: Chamomile Oil, Roman (Anthemis nobilis) EOS70 Page 1 of 8 1.1 Product Identifier Section 1. Identification of the substance or the mixture and of the supplier Product identifier: Chamomile oil, Roman (Anthemis nobilis); CAS: 84649-86-5 Other identifiers:

More information

: CITALOPRAM HYDROCHLORIDE CRS

: CITALOPRAM HYDROCHLORIDE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 16/12/2009 Version: 4.0 SECTION 1: Identification of the substance/mixture

More information

Safety Data Sheet - Version 5.0 Preparation Date 8/17/2016 Latest Revision Date (If Revised) SDS Expiry Date 8/16/2019

Safety Data Sheet - Version 5.0 Preparation Date 8/17/2016 Latest Revision Date (If Revised) SDS Expiry Date 8/16/2019 Safety Data Sheet - Version 5.0 Preparation Date 8/17/2016 Latest Revision Date (If Revised) SDS Expiry Date 8/16/2019 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product

More information

: RIZATRIPTAN BENZOATE CRS

: RIZATRIPTAN BENZOATE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 23/05/2011 Version: 2.0 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET Waffle Belgian Flavor

SAFETY DATA SHEET Waffle Belgian Flavor Section. Identification of the substance or the mixture and of the supplier Product Code: Product Name: Trade Name: Company Name: Web site address: 34583 Vapor Vapes, Inc 80 Catalina St, Seaside, CA 93955

More information

Section 1: Identification of the substance or mixture and the company

Section 1: Identification of the substance or mixture and the company Section 1: Identification of the substance or mixture and the company 1.1. Product Identifier Name: Solid Zinc (Zn) in various manufactured forms EC #: 231-175-3 CAS #: 7440-66-6 1.2 Relevant applications

More information

Application of the calculation method in regulatory risk assessment. Part 1 The issue of animal studies

Application of the calculation method in regulatory risk assessment. Part 1 The issue of animal studies Application of the calculation method in regulatory risk assessment Part 1 The issue of animal studies Dr. Tamara Coja, MSc Tox AGES, Institute for Plant Protection Products Are animal studies the ultimate

More information

SANITISER & DEGREASER

SANITISER & DEGREASER Date of issue: 28/06/2017 Revision date: 12/05/2016 : Version: 10.1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name Product

More information

SAFETY DATA SHEET. SECTION 1: Identification of the substance / mixture and of the company / undertaking.

SAFETY DATA SHEET. SECTION 1: Identification of the substance / mixture and of the company / undertaking. SAFETY DATA SHEET According to Regulation (EC) No. 1907/2006 (REACH) and its amendments. Date of issue: 01.02.2017 Version number: 2.0 Date of verification: 01.02.2017 SECTION 1: Identification of the

More information

Pepsin Powder. Section 1: Identification of the substance/ mixture and of the company/ undertaking.

Pepsin Powder. Section 1: Identification of the substance/ mixture and of the company/ undertaking. Revision date 08-04-2016 1.1 Product identifier Section 1: Identification of the substance/ mixture and of the company/ undertaking. Product name Other names CAS No. 9001-75-6 Index No. 647-008-00-6 EC

More information

: ARGININE HYDROCHLORIDE CRS

: ARGININE HYDROCHLORIDE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 25/11/2009 Version: 7.0 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET. SECTION 1: Identification of the substance/mixture and of the company/undertaking

SAFETY DATA SHEET. SECTION 1: Identification of the substance/mixture and of the company/undertaking SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Trade name or designation of the mixture Registration number - Synonyms Product

More information

Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) Fax: + 44 (0)

Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) Fax: + 44 (0) SECTION 1: COMPANY AND PRODUCT IDENTIFICATION Fellowes UK Yorkshire Way, West Moor Park Doncaster, South Yorkshire DN3 3FB UK Telephone: + 44 (0) 1302 836800 Fax: + 44 (0) 1302 836899 Product Name: Description:

More information

In accordance with REACH Regulation EC No.1907/2006 LUSCIOUS VANILLA. Section 1. Identification of the substance or the mixture and of the supplier

In accordance with REACH Regulation EC No.1907/2006 LUSCIOUS VANILLA. Section 1. Identification of the substance or the mixture and of the supplier Page 1 ( 9 ) Section 1. Identification of the substance or the mixture and of the supplier 1.1 Product Identifier Product identifier: Other identifiers: COS 1362/2 $LUSVANCOSX(Contains:Cinnamic aldehyde,

More information

Cobalt (II) Sulphate 7-Water

Cobalt (II) Sulphate 7-Water Revision date 08-04-2016 1.1 Product identifier Cobalt (II) Sulphate 7-Water Section 1: Identification of the substance/ mixture and of the company/ undertaking. Product name Other names Cobalt (II) Sulphate

More information

MATERIAL SAFETY DATA SHEET

MATERIAL SAFETY DATA SHEET This safety data sheet conforms to Regulation (EC) No. 1272/2008. Version 3 18.09.15 1.0 IDENTIFICATION OF THE SUBSTANCE/ PREPARATION AND COMPANY 1.1 PRODUCT IDENTIFIERS Product name : AVD Foam (Aqueous

More information

REVISION NUMBER: N/A SAFETY DATA SHEET. Use as a horticultural/amenity fertiliser

REVISION NUMBER: N/A SAFETY DATA SHEET. Use as a horticultural/amenity fertiliser SDS COMPLETED 5 TH FEBRUARY 2015 VERSION 01 SUPERSEDES SDS: N/A REVISION NUMBER: N/A SAFETY DATA SHEET 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product Identifier:

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page 1 ( 8 ) (20/08/2014) Section 1. Identification of the substance or the mixture and of the supplier 1.1 Product Identifier Product identifier: Bergamot oil Expressed; CAS: 8007-75-8 Other identifiers:

More information

: LISINOPRIL DIHYDRATE CRS

: LISINOPRIL DIHYDRATE CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 04/02/2010 Version: 5.0 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET according to 1907/2006/EC, Article 31

SAFETY DATA SHEET according to 1907/2006/EC, Article 31 SAFETY DATA SHEET according to 197/26/EC, Article 31 Thermal Compound (S66C) SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product name Thermal

More information

Nickel (II) Sulphate Hydrated

Nickel (II) Sulphate Hydrated Revision date 08-04-2016 1.1 Product identifier Nickel (II) Sulphate Hydrated Section 1: Identification of the substance/ mixture and of the company/ undertaking. Product name Other names Nickel (II) Sulphate

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 9 (26/06/205 BRANDY BUTTER FRAGRANCE OIL (BRANDYBUTTERND Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers: BRANDY

More information

SAFETY DATA SHEET according to Regulation (EC) No 1907/2006

SAFETY DATA SHEET according to Regulation (EC) No 1907/2006 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product name: Synonyms: doxium EC number: 243-531-5 CAS number: 20123-80-2 (anhydrous substance)

More information

Safety Data Sheet. according to Regulation (EC) No 1907/2006. Coltoflax Base

Safety Data Sheet. according to Regulation (EC) No 1907/2006. Coltoflax Base Coltoflax Base Revision date: 20.04.2015 Print date: 20.04.2015 Page 1 of 3 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Coltoflax Base 1.2.

More information

SAFETY DATA SHEET according to Regulation (EU) 2015/830

SAFETY DATA SHEET according to Regulation (EU) 2015/830 CP1478 v1.4 RS 756-8881, 756-889, 756-89, 756-894, 756-897, 8-7646, 8-7658 RS CLP/GHS revision date : 1/3/18 SAFETY DATA SHEET according to Regulation (EU) 215/83 Page 1/5 SECTION 1: Identification of

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 9 (20/06/207. Product Identifier Section. Identification of the substance or the mixture and of the supplier Product identifier: Other identifiers: UNICORN SPARKLE (Contains:alpha iso methyl ionone,

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 9 Issue date: 4/07/205 (8/05/205 GREEN APPLE FRAGRANCE OIL (GAPPLE-0 Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers:

More information

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification of the substance or the mixture and of the supplier Page ( 7 (08/04/206 Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers: None.2 Relevant identified uses of the substance

More information

Safety Data Sheet - Version 5.0 Preparation Date 6/1/2016 Latest Revision Date (If Revised) SDS Expiry Date 5/31/2019

Safety Data Sheet - Version 5.0 Preparation Date 6/1/2016 Latest Revision Date (If Revised) SDS Expiry Date 5/31/2019 Safety Data Sheet - Version 5.0 Preparation Date 6/1/2016 Latest Revision Date (If Revised) SDS Expiry Date 5/31/2019 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 9 (29/06/205 PATCHOULI FRAGRANCE OIL (PATCHOULI Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers: PATCHOULI FRAGRANCE

More information

SAFETY DATA SHEET. Allyl phenoxyacetate

SAFETY DATA SHEET. Allyl phenoxyacetate SAFETY DATA SHEET SECTION 1 Identification of the substance/mixture and of the company/undertaking Product identifiers Product name Allyl phenoxyacetate W203807 REACH No. CAS-No. 7493-74-5 Product Number

More information

Safety Data Sheet Safety Data Sheet in accordance with Regulation (EC) No. 1907/2006, as amended.

Safety Data Sheet Safety Data Sheet in accordance with Regulation (EC) No. 1907/2006, as amended. in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 16/12/2009 Version: 3.0 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET. Date: April 11, Product Name: Paraformaldehyde, 4% in PBS Ready-to Use Fixative Catalog Number: 22023

SAFETY DATA SHEET. Date: April 11, Product Name: Paraformaldehyde, 4% in PBS Ready-to Use Fixative Catalog Number: 22023 1. PRODUCT AND COMPANY IDENTIFICATION SAFETY DATA SHEET Date: April 11, 2018 Product Name: Paraformaldehyde, 4% in PBS Ready-to Use Fixative Catalog Number: 22023 Unit Size: 5x20mL Manufacturer/Supplier:,

More information

: Resinomer Catalyst. SECTION 1: Identification of the substance/mixture and of the company/undertaking. SECTION 2: Hazards identification

: Resinomer Catalyst. SECTION 1: Identification of the substance/mixture and of the company/undertaking. SECTION 2: Hazards identification Date of issue: 11/25/2014 Revision date: 03/06/2015 Version: 1.1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name : Mixture

More information

SAFETY DATA SHEET ULTIMEG 2220

SAFETY DATA SHEET ULTIMEG 2220 Revision Date 07/11/2012 Revision 3 Supersedes date 02/02/2012 SAFETY DATA SHEET According to Regulation (EU) No 453/2010 According to Regulation (EC) No 1907/2006 According to EC Directive 2001/58/EC

More information

SAFETY DATA SHEET. Section 1. Identification of the substance or the mixture and of the supplier. Section 2. Hazards identification

SAFETY DATA SHEET. Section 1. Identification of the substance or the mixture and of the supplier. Section 2. Hazards identification Page ( 8 Issue date: 04/24/208 (04/23/208 AMISH KITCHEN (DEP FREE. Product Identifier Section. Identification of the substance or the mixture and of the supplier Product identifier: Other identifiers:

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier Page ( 9 Issue date: 4/07/205 (4/07/205 GRAPEFRUIT FRAGRANCE OIL (GFRUIT2 Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers:

More information

: Proteinase K (Molecular Biology Grade)

: Proteinase K (Molecular Biology Grade) Date of issue: 11/07/2018 Revision date: 11/07/2018 Version: 1.3 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name Product

More information

This safety data sheet conforms to Regulation (EC) No. 1272/2008. Version

This safety data sheet conforms to Regulation (EC) No. 1272/2008. Version This safety data sheet conforms to Regulation (EC) No. 1272/2008. Version 1-05.10.17 1.0 IDENTIFICATION OF THE SUBSTANCE/ PREPARATION AND COMPANY 1.1 PRODUCT IDENTIFIERS Product name: FR-DB4 1.2 RELEVANT

More information

EU Safety Data Sheet. Enzyme Conjugate. 1 Identification of the substance/mixture and of the company

EU Safety Data Sheet. Enzyme Conjugate. 1 Identification of the substance/mixture and of the company nonr 1 Identification of the substance/mixture and of the company 1.1 Trade Name (As Labeled): 1.2 Product Use: Used as for HCP ELISA. For in-vitro use only 1.3 Manufacturer s Name: BioGenes GmbH Address:

More information

Safety Data Sheet - Version 5.0 Preparation Date 5/20/2015 Latest Revision Date (If Revised) SDS Expiry Date 5/18/2018

Safety Data Sheet - Version 5.0 Preparation Date 5/20/2015 Latest Revision Date (If Revised) SDS Expiry Date 5/18/2018 Safety Data Sheet - Version 5.0 Preparation Date 5/20/2015 Latest Revision Date (If Revised) SDS Expiry Date 5/18/2018 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product

More information

FoodDrinkEurope Position on GLP studies

FoodDrinkEurope Position on GLP studies FoodDrinkEurope Position on GLP studies Content of the presentation Introduction to GLP Importance of GLP for the food industry Use of GLP based on the example of novel foods Conclusions GLP what is it?

More information

SIGMA-ALDRICH. Material Safety Data Sheet Version 4.0 Revision Date 02/28/2010 Print Date 08/24/2011

SIGMA-ALDRICH. Material Safety Data Sheet Version 4.0 Revision Date 02/28/2010 Print Date 08/24/2011 SIGMA-ALDRICH sigma-aldrich.com Material Safety Data Sheet Version 4.0 Revision Date 02/28/2010 Print Date 08/24/2011 1. PRODUCT AND COMPANY IDENTIFICATION Product name : Product Number : D206539 Brand

More information

ZYBAX AIR MATERIAL SAFETY DATA SHEET

ZYBAX AIR MATERIAL SAFETY DATA SHEET ZYBAX AIR MATERIAL SAFETY DATA SHEET Date of issue 28/05/2015 eco-friendly odour removal For more information visit www.zybax.co.uk 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING

More information

Safety Data Sheet. according to Regulation (EC) No. 1907/2006. Cinnamon bark ceylanicum CO2-se extract_ Print date:

Safety Data Sheet. according to Regulation (EC) No. 1907/2006. Cinnamon bark ceylanicum CO2-se extract_ Print date: Print date: 02.11.2011 Page 1 of 7 SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifier Further trade names Zimtrinden ceylanicum CO2-se Extrakt (ökol.),

More information

SAFETY DATA SHEET. SECTION 1 Identification of the substance/mixture and of the company/undertaking. SECTION 2 Hazards identification

SAFETY DATA SHEET. SECTION 1 Identification of the substance/mixture and of the company/undertaking. SECTION 2 Hazards identification SAFETY DATA SHEET SECTION 1 Identification of the substance/mixture and of the company/undertaking 1.1 Product identifier - Product Name: 1.2 Relevant identified uses of the substance or mixture and uses

More information

SAFETY DATA SHEET Jeyes Fluid

SAFETY DATA SHEET Jeyes Fluid Revision Date 25/09/2017 SAFETY DATA SHEET Jeyes Fluid SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product name Jeyes Fluid Product No. JF02

More information

SAFETY DATA SHEET (SDS) According to EC Regulation 1907/2006/EC and Subsequent Amendments

SAFETY DATA SHEET (SDS) According to EC Regulation 1907/2006/EC and Subsequent Amendments A42 SUPER GLUE 01 IDENTIFICATION OF THE SUBSTANCE AND OF THE COMPANY Trade Name : DEMSUN A42 SUPER GLUE Company : AKTEK DIŞ TİCARET LTD ŞTİ Adress : Yeşilbayır Mah. Şimşir Sk. No: 20 34555 Hadımköy İstanbul

More information

: TETRACYCLINE HYDROCHLORIDE CRS

: TETRACYCLINE HYDROCHLORIDE CRS Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 10/12/2009 Version: 7.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product

More information

Section 1: Identification of the Substance/Mixture and of the Supplier

Section 1: Identification of the Substance/Mixture and of the Supplier SAFETY DATA SHEET Section 1: Identification of the Substance/Mixture and of the Supplier Product Name: SOLDERING FLUX Proper Shipping Name Zinc chloride solution Recommended use: Soldering Flux Company

More information

: PROMETHAZINE IMPURITY D CRS

: PROMETHAZINE IMPURITY D CRS in accordance with Regulation (EC) No. 1907/2006, as amended. Date of issue: 30/08/2013 Revision date: 30/08/2013 Supersedes: 27/06/2013 Version: 3.1 SECTION 1: Identification of the substance/mixture

More information

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification. Section 2. Hazard(s) identification

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification. Section 2. Hazard(s) identification 1 1 (06/22/2018) Section 1. Identification Product Identifier Product identifier: Other identifiers: Recommended use of the chemical and restrictions on use Product uses: Supplier Details ocardenas@fragrancewest.com

More information

PART 3 HEALTH HAZARDS

PART 3 HEALTH HAZARDS PART 3 HEALTH HAZARDS - 107 - CHAPTER 3.1 ACUTE TOXICITY 3.1.1 Definition Acute toxicity refers to those adverse effects occurring following oral or dermal administration of a single dose of a substance,

More information

SAFETY DATA SHEET according to Regulation (EU) 2015/830

SAFETY DATA SHEET according to Regulation (EU) 2015/830 CP1477 v1.6 RS 756-8869, 756-8871, 756-8878, 8-7652, 8-7661 RS CLP/GHS revision date : 1/3/19 SAFETY DATA SHEET according to Regulation (EU) 215/83 1/5 date SECTION 1: Identification of the substance/mixture

More information

Fryolux Tinning Compound

Fryolux Tinning Compound Page /6 SECTION : Identification of the substance/mixture and of the company/undertaking.. Product identifier Product name.3. Details of the supplier of the safety data sheet Company Address The Solder

More information

: GLUTAMIC ACID CRS. Safety Data Sheet Safety Data Sheet in accordance to Regulation (EC) No. 1907/2006, as amended.

: GLUTAMIC ACID CRS. Safety Data Sheet Safety Data Sheet in accordance to Regulation (EC) No. 1907/2006, as amended. in accordance to Regulation (EC) No. 1907/2006, as amended. Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 30/10/2007 Version: 5.0 SECTION 1: Identification of the substance/mixture and

More information

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with REACH Regulation EC No.1907/2006. Section 1. Identification of the substance or the mixture and of the supplier ( 0 Issue date: 08/07/205 (08/07/205 CHOCOLATE ORANGE FRAGRANCE OIL (CHOCO-JAS Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other

More information

SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006

SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 AXCELA Version 1.1 / EN Revision Date 19.08.2013 Print Date 23.09.2013 1. Identification of the substance/mixture and of the company/undertaking

More information

: Citric Acid Assay Kit

: Citric Acid Assay Kit Citric Acid Assay Kit Kit Safety Information Sheet Date of issue: 05/06/2013 Revision date: 22/11/2017 Supersedes: 02/03/2017 Version: 1.3 SECTION 1: Kit identification 1.1. Kit identifier Product name

More information

: Protease (Subtilisin A from Bacillus licheniformis) Powder

: Protease (Subtilisin A from Bacillus licheniformis) Powder Protease (Subtilisin A from Bacillus licheniformis) Powder Date of issue: 25/02/2014 Revision date: 20/09/2017 Supersedes: 12/01/2017 Version: 1.3 SECTION 1: Identification of the substance/mixture and

More information

SAFETY DATA SHEET PURI-BENT

SAFETY DATA SHEET PURI-BENT SAFETY DATA SHEET PURI-BENT Section 1: Identification of the Substance and of the Company 1.1 Product Identifier: Product Name: PURI-BENT Synonyms: CAS Number: 1302-78-9 1.2 Relevant Identified uses of

More information

SAFETY DATA SHEET SECTION 1 - IDENTIFICATION

SAFETY DATA SHEET SECTION 1 - IDENTIFICATION SAFETY DATA SHEET SECTION 1 - IDENTIFICATION Product Identifier: RP-OCNF LIFT STATION DEGREASER Recommended Use: RED SOLVENT LIFT STATION DEGREASER Restrictions on Use: INDUSTRIAL OR PROFESSIONAL USE ONLY

More information

SAFETY DATA SHEET SYMBIO LIQUID MAGNESIUM

SAFETY DATA SHEET SYMBIO LIQUID MAGNESIUM 1. Identification of the substance/mixture and of the company/undertaking 1.1 Product Identifier: Symbio Liquid Magnesium 1.2 Relevant uses of the substance or mixture and uses advised against: Use as

More information

Lead Metal and the 9 th ATP to CLP: Frequently Asked Questions

Lead Metal and the 9 th ATP to CLP: Frequently Asked Questions Lead Metal and the 9 th ATP to CLP: Frequently Asked Questions Commission Regulation (EU) 2016/1179 commonly known as the 9 th ATP to CLP was published in the Official Journal of the European Union on

More information

MMC International. MSDS Material Safety Data Sheet. 1. Identification of the substance/mixture and of the company

MMC International. MSDS Material Safety Data Sheet. 1. Identification of the substance/mixture and of the company 1. Identification of the substance/mixture and of the company 1.1 Product identifiers Product name : Product number : Brand : Crystal meth/xtc Test METAM0110 MMC International 1.2 Relevant identified uses

More information

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification of the substance or the mixture and of the supplier

SAFETY DATA SHEET. In accordance with 29 CFR Section 1. Identification of the substance or the mixture and of the supplier Page ( 8 Issue date: /30/206 (/30/206 Section. Identification of the substance or the mixture and of the supplier. Product Identifier Product identifier: Other identifiers: None.2 Relevant identified uses

More information

: SODIUM HYALURONATE BRP

: SODIUM HYALURONATE BRP Date of issue: 27/06/2013 Revision date: 27/06/2013 Supersedes: 04/03/2008 Version: 5.0 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product

More information

Safety Data Sheet Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH)

Safety Data Sheet Safety Data Sheet according to Regulation (EC) No. 1907/2006 (REACH) according to Regulation (EC) No. 1907/2006 (REACH) This is prepared voluntarily: it is not required according to Article 31 of Regulation (EC) No 1907/2006 Section 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE

More information

SAFETY DATA SHEET Clean Hands

SAFETY DATA SHEET Clean Hands Clean Hands Page 1 of 9 SAFETY DATA SHEET Clean Hands The safety data sheet is in accordance with Commission Regulation (EU) 2015/830 of 28 May 2015 amending Regulation (EC) No 1907/2006 of the European

More information

Safety Data Sheet. according to Regulation (EC) No 1907/2006. Coltex Extrafine mix

Safety Data Sheet. according to Regulation (EC) No 1907/2006. Coltex Extrafine mix Page 1 of 6 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier 1.2. Relevant identified uses of the substance or mixture and uses advised against

More information

: Aeliteflo. SECTION 1: Identification of the substance/mixture and of the company/undertaking. SECTION 2: Hazards identification

: Aeliteflo. SECTION 1: Identification of the substance/mixture and of the company/undertaking. SECTION 2: Hazards identification Date of issue: 12/03/2014 Revision date: 02/19/2015 Version: 1.1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form Product name : Mixture

More information

May be harmful if inhaled. May cause respiratory tract irritation. Skin. May be harmful if absorbed through skin. May cause skin irritation.

May be harmful if inhaled. May cause respiratory tract irritation. Skin. May be harmful if absorbed through skin. May cause skin irritation. SIGMA-ALDRICH sigma-aldrich.com Material Safety Data Sheet Version 4.0 Revision Date 02/27/2010 Print Date 05/11/2010 1. PRODUCT AND COMPANY IDENTIFICATION Product name : Naproxen sodium Product Number

More information

Safety Data Sheet SECTION 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING

Safety Data Sheet SECTION 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Safety Data Sheet SECTION 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Catalog Number: XAN-5040 Product Name: OxiSelect Trolox Equivalent Antioxidant Capacity (TEAC) Assay

More information