WOUND DRESSING Daily Dressing Packets

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1 AMERIGEL WOUND DRESSING Daily Dressing Packets P R O D U C T I N F O R M AT I O N MSDS APPLICATION PROTOCOLS

2 AmeriGel WOUND DRESSING Daily Dressing Packets A HYDROGEL WITH A UNIQUE AUTOLYTIC DEBRIDER Diabetic Skin Ulcers Insufficiency (Stasis) Ulcers Stage I - IV Pressure Ulcers Friction Tears/Abrasions 1st and 2nd Degree Burns Post Surgical Incisions ANTIMICROBIAL & ANTIFUNGAL For use as a wound dressing to manage pressure ulcers stages I - IV, stasis ulcers, diabetic skin ulcers, 1st and 2nd degree burns, post-surgical incisions, cuts, abrasions and skin irritations associated with peristomal care. Easy and economical to use. Maintains a moist wound environment which promotes healing. Also can be used with other Amerigel products to provide additional moisture and protection for at-risk skin. Physician approved and recommended. TRY OUR OTHER PRODUCTS AmeriGel Wound Dressing AmeriGel Hydrogel Saturated Gauze Dressing Amerigel Care Lotion Amerigel Barrier Lotion Amerigel Wound Wash 1300 S. Highland Avenue Clearwater, FL Visit our Website:

3 MATERIAL SAFETY DATA SHEET I. PRODUCT IDENTIFICATION PRODUCT: AMERIGEL WOUND DRESSING DAILY DOSE PACKETS II. COMPOSITION/INGREDIENTS COMPONENTS: Polyethylene Glycol 400 Polyethylene Glycol 3350 Oak Extract (Oakin ) Meadowsweet Extract Zinc Acetate III. PHYSICAL AND CHEMICAL CHARACTERISTICS MELTING POINT: <150ºF SOLUBILITY IN WATER: Soluble APPEARANCE & ODOR: Cloudy, viscous, ointment with mild odor SPECIFIC GRAVITY: <1.3 IV. PHYSICAL HAZARDS STABILITY: CONDITIONS TO AVOID: MATERIALS TO AVOID: HAZARDOUS THERMAL DECOMPOSITION PRODUCTS: HAZARDOUS POLYMERIZATION CONDITIONS: Stable At elevated temperatures separation may occur Avoid mixing with strong oxidizing agents or acids Carbon dioxide and carbon monoxide Does not occur V. HEALTH HAZARD DATA LD50: SKIN IRRITATION: EYE IRRITATION: Not toxic Some erythema and edema Possible irritant VI. FIRST-AID MEASURES EYES: Promptly flush eyes with copious amount of water for 15 minutes. If redness or pain persists over 24 hours, consult a physician. INGESTION: Wash mouth out with water. Contact physician. INHALATION: Product is not volatile.

4 VII. FIRE FIGHTING MEASURES FIRE EXTINGUISHING MEDIA: FIRE FIGHTING PROCEDURE: Dry chemical, carbon dioxide, water or regular foam. Do not scatter with high pressure water spray. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin. VIII. EXPOSURE CONTROL/PERSONAL PROTECTION VENTILATION: PROTECTIVE EQUIPMENT: Normal fresh air None IX. SPECIAL PRECAUTIONS AND SPILL/LEAK PROCEDURES STORAGE RECOMMENDATIONS: SPILL/LEAK PROCEDURES: WASTE DISPOSAL METHODS: Avoid direct sunlight. Store away from incompatible materials. Observe all federal, state and local regulations when storing. Dispose of material when expiration date has been reached. Sweep or shovel into closable container for disposal. Landfill disposal is suggested, but local and federal regulations must be followed. X. OTHER INFORMATION ISSUE DATE: March 2003 AMERX HEALTH CARE CORPORATION 1300 S. Highland Avenue Clearwater, FL Phone: The statements contained herein are believed to be true and are offered only for informational purposes. They are intended to be followed only by persons having related technical skills and at their own discretion and risk. Since conditions and manner of use are outside our control, we make no warranties, expressed or implied, and assume no liability in connection with any use of this information.

5 HEALING OBSERVATION NOTES TO TREATMENT PERSONNEL WHEN USING AMERIGEL PRODUCTS There is a definable sequence of events in the healing cascade of a chronic ulcer. The sequelae are predictable, given some experiences with Amerigel products. Although you will find some variance as to which day they occur, the steps are: DAY 1 - DAY If a wound is clean and no debridement of eschar is required after approximately two to five days of treatment, the wound may become erythematous, presenting a vibrant red, beefsteak appearance. Patients may complain of tingling/burning sensations in the wound site. Tingling/ burning may last up to five to seven days, however the intensity and duration of the sensation decreases with each succeeding day of treatment. Additionally, treatment personnel may notice an increase of sloughing/drainage produced by the wound by day two. During days five - fifteen, the wound may continue with peripheral erythema, but in reduced amounts. During this period, treatment personnel will note the addition of granulation tissue, especially in the periphery of the wound. It should be present and be a pink to bright red, beefsteak color. Upon close examination, treatment personnel will note the addition of various clumps of mother-daughter (M-D) cell proliferation. M-D cells will begin to form islands and form clumps or buds as the epithelium begins to form. As the re-epithelization continues to completion, tissue formation will be observed throughout the wound bed and especially around the periphery of the wound. Note that the wound then begins to heal from the bottom up to the top, and from the edges inward toward the center. DAY 15 - DAY You may observe periods of plateau or resting. Continue the treatment as before and the cycle observed in days one thru fifteen. Should you note that the wound appears to be regressing instead of progressing, treatment personnel should reduce the total dose of the product applied to the area. Usually the most efficient way to control the total dose applied is to reduce the treatment regiment from BID to QD. You should note the reestablishment of healing within two to four days. In the event the ulcer has developed undermining or tunneling, personnel should determine the extent of tunneling by inserting a cotton-tipped applicator as far as it will go, without using undue force. Raise the distal end of the application so that it may be seen or felt on the skin surface. Mark the spot with a felt pen and measure the extent of tunneling. Exudate needs to be considered and addressed accordingly.

6 PROTOCOL FOR USING AMERIGEL WOUND DRESSING Pressure and chronic ulcers are one of the most often preventable and treatable conditions among the elderly with restricted mobility. Development of pressure or chronic ulcers can have serious health consequences for elderly patients and can be costly and laborious to manage. Prevention of pressure or chronic ulcer development is widely acknowledged to be 2.5 times less expensive than treatment. The following protocol is recommended for the use of AmeriGel Wound Dressing on patients who are at-risk for developing or who have developed chronic ulcers. The nature of the wound and consideration of its size and depth will guide the selection of the appropriate topical therapy. Topical therapy includes cleansing of the area, debridement, dressings and the use of adjunctive therapies Wound site should be cleansed at each dressing change. Saline solutions are considered safe and effective for cleansing most pressure ulcers. Irrigating pressure of 8 to 11 pounds per square inch is considered safe and effective. Povidone Iodine, sodium hypochloride (Dakin s Solution), acetic acid (vinegar) and hydrogen peroxide should not be used since they are known to be toxic to fibroblasts and diminish the granulation process. Necrotic tissue that can develop with a chronic ulcer delays wound healing and provides a medium for bacterial contamination. Therefore, all wounds should be assessed on a weekly basis. Crosshatching of eschar with scalpel may speed autolytic debridement process. Apply AmeriGel Wound Dressing twice daily for the first week, then once daily thereafter. Apply a thin layer sparingly to wound surface. Make sure AmeriGel Wound Dressing is applied to all areas of the wound site, including areas of tunneling or undermining. In areas of undermining, impregnating gauze with a small amount of AmeriGel may be used as packing. AmeriGel should also be applied to the periwound area, up to 1/2 inch of the surrounding skin. The product is designed so that body heat causes the product to liquefy into the wound crevices. Cover the wound site with a dressing of choice appropriate to the wound size. Wound site may be covered with moist saline dressing, depending upon the patient s tolerance and location of the wound.

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