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1 Corporate Development Contact us: Royal Derby Hospital Uttoxeter Road Derby DE22 3NE Tel: Minicom: Follow us on Tuesday 6 th October 2015 Request under Freedom of Information Act 2000 Thank you for your request for information that has been processed under reference number Please provide the below information for the following conditions that can be treated through drug-delivery to home; Multiple Sclerosis () and Rheumatoid Arthritis (RA). 1. For each of the above conditions/therapies, please indicate how many patients are treated under the following circumstances: Total number of patients Condition Drug 2011/ / /14 In hospital** e.g. RA Drug 1 In hospital** e.g. RA Drug 2 In hospital** e.g. Drug 1 Hospitalprovided at- home Hospitalprovided at- home RA ADALIMUMAB RA CERTOLIZUMAB delivery by home RA ETANERCEPT

2 healthcare RA METHOTREXATE RA GOLIMUMAB BETA - 1a (AVONEX) BETA-1b (BETAFERON) BETA-1b (EXTAVIA) FINGOLIMOD GLATIRAMER ACETATE BETA - 1a (REBIF) Total **We are unable to provide you with this information, as we do not hold this data electronically. 2. For each of drug delivery services that you use, please indicate for the last three years: a. Name of provider - Evolution, Healthcare At Home, Boots, Alcura, Bupa, Medco, Pharmaxo b. Which home- appropriate conditions they treat Dermatology (Bupa, Healthcare at Home, Medco), (Bupa, Evolution, Healthcare at Home), RA (Alcura, Boots, Healthcare at Home, Medco), CF (Healthcare at Home), Crohns (Alcura, Healthcare at Home, Pharmaxo), Growth Hormone (Alcura, Healthcare at Home), HIV (Alcura Medco), Osteoporosis (Bupa), Parkinsons (Evolution), Renal (Healthcare at Home), Uvetitis (Healthcare at Home)

3 c. Which drugs are provided in this service current drugs ABACAVIR & LAMIVUDINE (KIVEXA) **HOMECARE** 600mg/300mg Tablets ABACAVIR **HOMECARE** 300 mg Tablets ACICLOVIR **HOMECARE** 400 mg Dispersible Tablets ADALIMUMAB ** HOMECARE DELIVERY ** 40 mg in 0.8mL Vial ADALIMUMAB **HOMECARE DELIVERY ONLY** 40 mg Pre-Filled Syringe ADALIMUMAB **HOMECARE DELIVERY ONLY** 40 mg Pre-Loaded Pen ADCAL-D3 **HOMECARE** Chewable Tablets APOMORPHINE **HOMECARE DELIVERY** 50 mg in 10mL Pre-Filled Syringe ATAZANAVIR **HOMECARE** 300 mg Capsules ATRIPLA **HOMECARE** Tablets AZATHIOPRINE **HOMECARE** 100mg in 5ml Suspension AZATHIOPRINE **HOMECARE** 25 mg Tablets AZATHIOPRINE **HOMECARE** 50 mg Tablets BETAMETHASONE VALERATE **HOMECARE** 0.1 % Cream BETAMETHASONE VALERATE **HOMECARE** 0.1 % Scalp Application BEZAFIBRATE **HOMECARE** 400 mg Modified Release Tablets CERTOLIZUMAB PEGOL **HOMECARE DELIVERY** 200 mg Pre-Filled Syringe CETIRIZINE **HOMECARE** 10 mg Tablets CHLORPHENAMINE **HOMECARE** 4 mg Tablets CICLOSPORIN (NEORAL) **HOMECARE** 10 mg Capsules CICLOSPORIN (NEORAL) **HOMECARE** 100 mg Capsules CICLOSPORIN (NEORAL) **HOMECARE** 100 mg in 1mL Oral Solution CICLOSPORIN (NEORAL) **HOMECARE** 25 mg Capsules CICLOSPORIN (NEORAL) **HOMECARE** 50 mg Capsules CLOBETASOL PROPIONATE **HOMECARE** 0.05 % Cream CLOTRIMAZOLE **HOMECARE** 1 % Cream CLOTRIMAZOLE HC **HOMECARE** 1 % Cream CODEINE PHOSPHATE **HOMECARE** 30 mg Tablets COLECALCIFEROL (HOMECARE) 20 micrograms (800 units) Capsules COLISTIMETHATE SODIUM **HOMECARE** (PROMIXIN) 1 mega unit Powder COLISTIMETHATE SODIUM **HOMECARE** (PROMIXIN) 1 mega unit Powder For Nebuliser Solution COLISTIMETHATE SODIUM **HOMECARE** 1 mega unit Injection CO-TRIMOXAZOLE **HOMECARE** 480 mg Tablets DAPSONE **HOMECARE** 50 mg Tablets DAPTOMYCIN **HOMECARE** 500 mg Injection DARUNAVIR **HOMECARE** 400 mg Tablets DARUNAVIR **HOMECARE** 600 mg Tablets DARUNAVIR **HOMECARE** 800 mg Tablets DIDANOSINE ** HOMECARE ** 250 mg Enteric Coated Capsules DIDANOSINE ** HOMECARE ** 400 mg Enteric Coated Capsules DIPROBASE **HOMECARE** Cream DOMPERIDONE **HOMECARE** 10 mg Tablets DORNASE ALFA (PULMOZYME) **HOMECARE** 2.5 mg Nebules DUODOPA CASSETTE **HOMECARE**

4 DUODOPA INITIATION KIT **HOMECARE** E45 **HOMECARE** Cream EFAVIRENZ **HOMECARE** 600 mg Film Coated Tablets EMTRICITABINE ** HOMECARE ** 200 mg Capsules ERTAPENEM **HOMECARE** 1 g Infusion ETANERCEPT **HOMECARE DELIVERY** 25 mg Injection ETANERCEPT **HOMECARE DELIVERY** 25 mg Pre-Filled Syringe ETANERCEPT **HOMECARE DELIVERY** 50 mg Pre-Filled Pen - **MYCLIC** ETANERCEPT **HOMECARE DELIVERY** 50 mg Pre-Filled Syringe EVIPLERA **HOMECARE** Tablets FERROUS FUMARATE **HOMECARE** 210 mg Tablets FERROUS SULPHATE **HOMECARE** 200 mg Tablets FINGOLIMOD **HOMECARE** 500 micrograms Capsules FLUCONAZOLE ** HOMECARE ** 50 mg Capsules FOLIC ACID **HOMECARE** 5 mg Tablets FOSAMPRENAVIR **HOMECARE** 700 mg Tablets GLATIRAMER ACETATE **HOMECARE DELIVERY** 20 mg in 1mL Pre-Filled Syringe GLATIRAMER ACETATE **HOMECARE DELIVERY** 40 mg/ml Pre-Filled Syringe GOLIMUMAB (SIMPONI) **HOMECARE** 100 mg Pre-Filled Pen GOLIMUMAB (SIMPONI) **HOMECARE** 50 mg Pre-Filled Pen IBUPROFEN **HOMECARE** 400 mg Tablets INFLIXIMAB in 250ml SODIUM CHLORIDE 0.9% **HOMECARE** INFUSION BETA - 1a (AVONEX BIO-SET) **HOMECARE DELIVERY** 30micrograms (6 million units) BETA - 1a (AVONEX BIO-SET) **HOMECARE DELIVERY** 30micrograms (6 million units) BETA - 1a (AVONEX) **HOMECARE DELIVERY** 30micrograms (6 million units) Pre-Filled BETA - 1a (AVONEX) **HOMECARE DELIVERY** 30micrograms (6 million units) BETA - 1a (AVONEX) **HOMECARE DELIVERY** 60micrograms (12 million units) BETA - 1a (REBIF) **HOMECARE DELIVERY** 22 micrograms (6 million units) in 0.5mL BETA - 1a (REBIF) **HOMECARE DELIVERY** 22 micrograms (6 million units) Pen BETA - 1a (REBIF) **HOMECARE DELIVERY** 22 micrograms (6 million units) Pre-Filled BETA - 1a (REBIF) **HOMECARE DELIVERY** 44 micrograms (12 million unis) Pen BETA - 1a (REBIF) **HOMECARE DELIVERY** 44 micrograms (12 million unis) Pre-Filled BETA - 1a (REBIF) **HOMECARE DELIVERY** 44 micrograms (12 million units) in 0.5m BETA - 1a (REBIF) **HOMECARE DELIVERY** Starter Pack Cartridge BETA - 1a (REBIF) **HOMECARE DELIVERY** Starter Pack Pen BETA - 1a (REBIF) **HOMECARE DELIVERY** Starter Pack Pre-Filled Syringe BETA-1b (BETAFERON) **HOMECARE DELIVERY** 300 micrograms (9.6 million units) BETA-1b (EXTAVIA) **HOMECARE DELIVERY** 300 micrograms (9.6 million units) Injection KALETRA **HOMECARE** (Lopinavir 200 mg & Ritonavir 50 mg) Tablets LAMIVUDINE 150mg & ZIDOVUDINE 300mg **HOMECARE** Tablets LISINOPRIL ** HOMECARE** 5 mg Tablets LOPERAMIDE **HOMECARE** 2 mg Capsules METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 10mg in 0.2ml Pre-Filled Pen METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 10mg in 0.2ml Pre-Filled Syringe METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 12.5mg in 0.25ml Pre-Filled Pen METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 15mg in 0.3ml Pre-Filled Pen

5 METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 15mg in 0.3ml Pre-Filled Syringe METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 20mg in 0.4ml Pre-Filled Pen METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 20mg in 0.4ml Pre-Filled Syringe METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 25mg in 0.5ml Pre-Filled Pen METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 25mg in 0.5ml Pre-Filled Syringe METHOTREXATE "HOMECARE DELIVERY ONLY" (Metoject) 7.5mg in 0.15ml Pre-Filled Pen METHOTREXATE **HOMECARE** 10 mg / 1mL (25mg in 2.5mL) Syrup METHOTREXATE **HOMECARE** 10 mg Tablets MULTIVITAMINS **HOMECARE** Tablets MYCOPHENOLATE MOFETIL (CELLCEPT) **HOMECARE** 1 g in 5mL Suspension MYCOPHENOLATE MOFETIL (CELLCEPT) **HOMECARE** 250 mg Capsules MYCOPHENOLATE MOFETIL (CELLCEPT) **HOMECARE** 500 mg Tablets MYCOPHENOLATE MOFETIL (MYFENAX) *HOMECARE* 250 mg Capsules MYCOPHENOLATE MOFETIL (MYFENAX) *HOMECARE* 500 mg Tablets MYCOPHENOLATE MOFETIL **HOMECARE** 250 mg Capsules MYCOPHENOLATE MOFETIL **HOMECARE** 500 mg Tablets MYCOPHENOLIC ACID (MYFORTIC) **HOMECARE** 180 mg Enteric Coated Tablets MYCOPHENOLIC ACID (MYFORTIC) **HOMECARE** 360 mg Enteric Coated Tablets NAPROXEN ** HOMECARE ** 500 mg Tablets NEVIRAPINE **HOMECARE** 200 mg Tablets NEVIRAPINE **HOMECARE** 400 mg Modified Release Tablets NURSE CHARGE *HOMECARE* PARACETAMOL **HOMECARE** 500 mg Tablets PRAVASTATIN **HOMECARE** 20 mg Tablets PRAVASTATIN **HOMECARE** 40 mg Tablets PREDNISOLONE **HOMECARE** 1 mg Tablets PREDNISOLONE **HOMECARE** 2.5 mg Enteric Coated Tablets PREDNISOLONE **HOMECARE** 25 mg Tablets PREDNISOLONE **HOMECARE** 5 mg Enteric Coated Tablets PREDNISOLONE **HOMECARE** 5 mg Soluble Tablets PREDNISOLONE **HOMECARE** 5 mg Tablets RALTEGRAVIR **HOMECARE** 400 mg Tablets RILPIVIRINE **HOMECARE** 25 mg Tablets RITONAVIR ** HOMECARE** 100 mg Tablets SIROLIMUS **HOMECARE** 1 mg in 1mL Oral Solution SIROLIMUS **HOMECARE** 1 mg Tablets SIROLIMUS **HOMECARE** 2 mg Tablets SIROLIMUS **HOMECARE** 500 micrograms Tablets SODIUM CHLORIDE **HOMECARE DELIVERY ONLY** 7 % Nebuliser Solution SOMATROPIN (GENOTROPIN MINI QUICK) **HOMECARE DELIVERY** 0.2 mg ( 0.6 units) Injection SOMATROPIN (GENOTROPIN MINI QUICK) **HOMECARE DELIVERY** 400 micrograms Injection SOMATROPIN (GENOTROPIN) **HOMECARE DELIVERY** 5.3mg (16 units) Cartridge SOMATROPIN (GENOTROPIN) **HOMECARE** 12mg (36 units) Injection SOMATROPIN (HUMATROPE) ** HOMECARE DELIVERY ONLY** 12mg (36 units) Cartridge SOMATROPIN (HUMATROPE) ** HOMECARE DELIVERY ONLY** 6mg (18 units) Cartridge SOMATROPIN (NORDITROPIN SIMPLEXx) **HOMECARE** 5 mg / 1.5mL Injection

6 SOMATROPIN (NUTROPIN AQ) ** HOMECARE DELIVERY** 10 mg in 2mL Cartridge SOMATROPIN (OMNITROPE) ** HOMECARE DELIVERY ONLY** 10mg (30 units) in 1.5mL Cartridge SOMATROPIN (OMNITROPE) ** HOMECARE DELIVERY ONLY** 5mg (15 units) in 1.5mL Cartridge SOMATROPIN (SAIZEN CLICK EASY) ** HOMECARE DELIVERY ONLY ** 8mg (24 units) Injection SOMATROPIN (SAIZEN) ** HOMECARE DELIVERY ONLY ** 12mg (36 units) Injection TACROLIMUS (ADOPORT) **HOMECARE** 1 mg Capsules TACROLIMUS (ADOPORT) **HOMECARE** 5 mg Capsules TACROLIMUS (ADOPORT) **HOMECARE** 500 micrograms Capsules TACROLIMUS (ADVAGRAF) **HOMECARE** 1 mg Modified Release Capsules TACROLIMUS (ADVAGRAF) **HOMECARE** 3 mg Modified Release Capsules TACROLIMUS (ADVAGRAF) **HOMECARE** 5 mg Modified Release Capsules TACROLIMUS (ADVAGRAF) **HOMECARE** 500 micrograms Modified Release Capsules TACROLIMUS (PROGRAF) **HOMECARE** 1 mg Capsules TACROLIMUS (PROGRAF) **HOMECARE** 5 mg Capsules TACROLIMUS (PROGRAF) **HOMECARE** 500 micrograms Capsules TEICOPLANIN REGIME *HOMECARE* 400 mg TEMAZEPAM **HOMECARE** 10 mg Tablets TENOFOVIR **HOMECARE** 245 mg Tablets TERIPARATIDE (FORSTEO) *** HOMECARE DELIVERY ONLY *** 20 micrograms per dose 3ml Pre-filled Pen TOBRAMYCIN (BRAMITOB) **HEALTHCARE AT HOME** 300 mg in 4mL Nebuliser Solution TRUVADA **HOMECARE** Tablets USTEKINUMAB (STELARA) **HOMECARE** 45 mg in 0.5mL Pre-Filled Syringe ZIDOVUDINE **HOMECARE** 100 mg Capsules ZIDOVUDINE **HOMECARE** 250 mg Capsules ZOPICLONE **HOMECARE** 3.75 mg Tablets d. How many patients are treated with the drug by this provider each year - This would take longer than 18 hours to determine this level of data and, therefore, pursuant of Section 12 of the Freedom of Information Act (Cost of compliance exceeds the appropraiate limit of 450, which equates to one person spending 18 hours in determining whether the Trust holds the information, locating, reviewing and extracting the data. We are, therefore, not obliged to process this matter further. e. For each of the above, please indicate the spend per-provider per-drug in each year - We are unable to provide this information under Section 43 of the Freedom of Information Act (Commercially sensitive information). *************************************************************************************************************** If you should have any further queries with regard to this matter please contact me at the above address. Please remember to quote the reference number above in any future communication. Please note that the information provided is the property of Derby Teaching Hospitals NHS Foundation Trust and subject to Intellectual Property and Database Rights. Any commercial application or use of this information may be subject to the provisions of the Re-use of Public Sector Information Regulations This means that if you wish to re-use the information

7 provided for commercial purposes for any reason you must ask us for permission to do so. Should we agree that you can use the information it will be subject to the issue of a licence which may or may not involve a fee. If you have any questions about this process please contact us at dhft.foi@nhs.net. If you are unhappy with the service you have received in relation to this request and wish to make a complaint or request a review of our decision, you should write to: The Chief Executive Derby Teaching Hospitals NHS Foundation Trust The Royal Derby Hospital Uttoxeter Road Derby DE22 3NE If you are not content with the outcome of your complaint, you may apply directly to the Information Commissioner for a decision. Generally, the Information Commissioner s Office cannot make a decision unless you have exhausted the complaints procedure provided by this Trust. The Information Commissioner can be contacted at: The Information Commissioner s Office Wycliffe House Water Lane Wilmslow Cheshire SK9 5AF Yours sincerely Jane Haywood Freedom of Information Officer

5 Infections. To be used in conjunction with NICE guidance, The British National Formulary for adults and/or children and

5 Infections. To be used in conjunction with NICE guidance, The British National Formulary for adults and/or children and 5 Infections To be used in conjunction with NICE guidance, The British National Formulary for adults and/or children and Southend University Hospital, Antibiotic Guidelines Index 5.1 Antibacterial drugs