CURRICULUM VITAE China Medical College, College of Medicine, Taichung, Taiwan, R.O.C.

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1 CURRICULUM VITAE NAME: Huang, Chung-Ming OFFICE ADDRESS: China Medical University Hospital, No. 2, Yuh-Der Road, Taichung, Taiwan, R.O.C., 北 路 2 EDUCATION: China Medical College, College of Medicine, Taichung, Taiwan, R.O.C. ACADEMIC APPOINTMENT: Lecturer, Department of Internal Medicine, China Medical University Assistant professor, Department of Internal Medicine, China Medical University present Associate professor, Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. Associate professor, Graduate Institute of Immunology, College of Medicine, China Medical University, Taichung, Taiwan. EMPLOYMENT RECORD: Resident, Department of Internal Medicine, Chief Resident, Department of Internal Medicine, Fellow, Section of Rheumatology, Allergy and Immunology Attending Physician, Section of Rheumatology, Allergy and Immunology. Department of Internal Medicine, 2006-present Chief of Rheumatology, Allergy and Immunology.

2 Department of Internal Medicine, PROFFESIONAL AFFINIATIONS: 1. Rheumatism Association, R.O.C, License no Chinese Society of Immunology, License no Formosan Medical Association 4. The society of Internal Medicine, R.O.C. License no PROFFESIONAL ACTIVITIES: 1. Chief of Section of Rheumatology, Allergy and Immunology. Department of Internal Medicine, 2. Member of transplantation committee in China Medical University Hospital 3. Member of Drug Adverse Event committee in Taichung,Taiwan,R.O.C 4. Inspector of Bureau of National Health Insurance in Taichung, Taiwan,R.O.C 5. Supervisor of Chinese Society of Immunology, R.O.C 6. Peer reviewer of A) Arthritis and Rheumatism B) J. Rheumatol, C) Rheumatology D) Annual of rheumatic disease 7. Peer reviewer of National Science Council in Taiwan Publications 1. Huang PH, Huang CM, Tsai FJ. Polymorphisms of the TAP2 genes in Chinese patients with SLE in Taiwan. Formosan J Rheumatol. 2008;22: Wan L, Lin YJ, Sheu JJ, Huang CM, Tsai Y, Tsai CH, Wong W, Tsai FJ. Analysis of ERCC2/XPD functional polymorphisms in systemic lupus erythematosus. Int J Immunogenet Nov Lo SF, Wan L, Lin HC, Huang CM, Tsai FJ. Association of CD4 Enhancer Gene Polymorphisms with Rheumatoid Arthritis and Systemic Lupus Erythematosus in Taiwan. J Rheumatol ;35: Lo SF, Huang CM, Lin HC, Chen WC, Tsai CH, Tsai FJ. Cytokine (IL-6) and chemokine (IL-8) gene polymorphisms among rheumatoid arthritis patients in Taiwan. Clin Exp Rheumatol. 2008;26:632-7.

3 5. Lin YJ, Wan L, Sheu JJ, Huang CM, Lin CW, Lan YC, Lai CH, Hung CH, Tsai Y, Tsai CH, Lin WY, Liu HP, Lin TH, Huang YM, Tsai FJ. G/T polymorphism in the interleukin-2 exon 1 region among Han Chinese systemic lupus erythematosus patients in Taiwan. Clin Immunol. 2008;129: Lin YJ, Wan L, Sheu JJ, Huang CM, Lin CW, Lan YC, Lai CH, Hung CH, Tsai Y, Tsai CH, Lin TH, Chen CP, Tsai FJ.A/C polymorphism in the interleukin-18 coding region among Taiwanese systemic lupus erythematosus patients. Lupus. 2008;17: Lee CC, Lin WY, Wan L, Tsai Y, Tsai CH, Huang CM, Chen CP, Tsai FJ. Association of interleukin-18 gene polymorphism with asthma in Chinese patients. J Clin Lab Anal. 2008;22: Chen ML, Tsai FJ, Tsai CH, Huang CM. Tumor necrosis factor-alpha and interleukin-4 gene polymorphisms in Chinese patients with gout. Clin Exp Rheumatol. 2007;25(3): Lee CC, Lin WY, Wan L, Tsai Y, Lin YJ, Tsai CH, Huang CM, Tsai FJ. Interleukin-18 gene polymorphism, but not interleukin-2 gene polymorphism, is associated with rheumatoid arthritis. Immunogenetics. 2007;59(6): Lin YJ, Wan L, Lee CC, Huang CM, Tsai Y, Tsai CH, Shin TL, Chao K, Liu CM, Xiao JW, Tsai FJ. Disease association of the interleukin-18 promoter polymorphisms in Taiwan Chinese systemic lupus erythematosus patients. Genes Immun. 2007;8(4): Huang CM, Lo SF, Lin HC, Chen ML, Tsai CH, Tsai FJ. Correlation of oestrogen receptor gene polymorphism with gouty arthritis. Ann Rheum Dis. 2006; 65(12): (Letter) 12. Huang CM, Huo AP, Tsai CH, Chen CL, Tsai FJ. Lack of association of interleukin-6 and interleukin-8 gene polymorphisms in Chinese patients with systemic lupus erythematosus. J Clin Lab Anal. 2006;20(6): Lin PW, Huang CM, Huang CC, Tsai CH, Tsai JJ, Chang CP, Tsai FJ. The association of -627 interleukin-10 promoter polymorphism in Chinese patients with systemic lupus erythematosus. Clin Rheumatol. 2007; 26(3): Lo SF, Huang CM, Tsai CH, Chien WC, Lai CC, Tsai Y, Tsai FJ. Androgen receptor gene polymorphism and rheumatoid arthritis in Taiwan. Clin Exp Rheumatol 2006;24: (Letter) 15. Tsai CH, Huang CM, Lo SF, Wan L, Tsai FJ. Interleukin-2 receptor gene polymorphism in Chinese patients with systemic lupus erythematosus. Rheumatol Int. 2006;26: (Letter) 16. Huang LH, Huang CM, Tsai FJ. Tumor necrosis factor-α gene promoter polymorphism in Chinese patients with systemic lupus erythematosus. J

4 Rheumatol ( ROC )2005;19: Lo SF, Huang CM, Tsai CH, Chen ML, Tsai FJ. Interleukin-1 receptor antagonist gene polymorphism in Taiwanese patients with gout. Clin Exp Rheumatol 2005; 23: Chou CT, Lin KC, Wei JC, Tsai WC, Ho HH, Hwang CM, Cherng JM, Hsu CM, Yu DT. Study of undifferentiated spondyloarthropathy among first-degree relatives of ankylosing spondylitis probands. Rheumatology (Oxford) 2005; 44: Lo SF, Huang CM, Lin HC,Tsai CH, Tsai FJ. Association of CYP17 gene polymorphism and rheumatoid arthritis in Chinese patients in central Taiwan. Rheumatol Int 2005; 25: Huang CM, Tsai CH, Chen CL, Chang CP, Tsai FJ. No relationship between -627 IL-10 promoter polymorphism and Chinese patient with RA. Rheumatol Int 2005; 25: Chen ML, Huang CM, Tsai JJP, Tsai FJ. Interleukin-1β gene polymorphisms in Taiwanese patients with gout. Rheumatol Int 2005; 25: Hsueh KC, Huang CM, Chen KJ, Hsu CH. Efficacy of autoantigen microarrays for detecting autoantibodies in patients with systemic lupus erythematosus. M Taiwan J Med 2005; 10: Huang CM, Tsai CH, Chen CL, Chang CP, Lai CC, Tsai FJ. Epidermal Growth Factor Receptor (EGFR) gene Bsr I Polymorphism Is Associated with Systemic Lupus Erythematosus. Lupus 2004; 13: Chu SL, Chen KJ, Tsai CY, Huang CM, Hsu CH. Efficacy of allergen-arrayed chips for detecting allergen-specific immunoglobulin E in allergic patients. M Taiwan J Med 2004; 9: Huang CM, Tsai JJP. Kung PT, Chen CL, Wu JY, Tsai FJ. The Relationship betweeninsulin-like Growth Factor-II Gene Apa I Polymorphism and RA. Scan J Rheumatol 2004; 33: (Letter) 26. Huang CM, Chen CL, Tsai JJP, Tsai CH, Tsai FJ. Association between Urokinase Gene 3 -UTR T/C Polymorphism and Chinese Patients with Rheumatoid Arthritis in Taiwan. Clin Exp Rheumatol 2004; 22: Yu MC, Huang CM, Wu MC, Wu JY, Tsai FJ. Association of TAP1 and TAP2 gene Polymorphisms in Chinese Patients with Rheumatoid Arthritis. Clin Rheumatol 2004; 23: Huang CM, Hang LW, Chen CL, Wu JY, Tsai FJ. Polymorphisms of TAP1 transporter genes in Chinese patients with SLE in Taiwan. Rheumatol Int 2004; 24: Huang CM, Tsai JJP, Tsai FJ, Chen WJ, Chen CL. Insulin-like growth factor-ii

5 gene Apa I polymorphism was not associated with SLE. Lupus 2003; 12: (Letter) 30. Lo SF, Huang CM, Wu MC, Wu JY, Tsai FJ. Lack of association of TNF gene polymorphism in Chinese patients with RA in central Taiwan. Rheumatol Int 2003; 23: Wu MC, Huang CM, Chen HY, Tsai FJ. Polymorphisms of the Interleukin-4 Gene in Chinese Patients with Systemic Lupus Erythematosus in Taiwan. Lupus 2003; 12: Huang CM, Wu MC, Wu JY, Tsai FJ. Association of vitamine D receptor gene Bsm-I polymorphisms in Chinese patients with SLE. Lupus 2002; 11: Huang CM, Wu MC, Wu JY, Tsai FJ. No association of vitamin-d receptor gene start condon Fok I polymorphisms in Chinese patients with SLE. J Rheumatol 2002; 29: Huang CM, Wu MC, Wu JY, Tsai FJ. Interleukin-1 receptor antagonist gene polymorphism in Chinese patients with systemic lupus erythematosus. Clin Rheumatol 2002; 21: Huang CM, Wu MC, Wu JY, Tsai FJ. No association of IL-4 gene polymorphisms in Chinese patients with RA in Taiwan. Clin Exp Rheumatol 2002; 20: (letter) 36. Huang CM, Wu MC, Wu JY, Tsai FJ. Lack of association of IL-1 gene polymorphisms in Chinese patients with SLE. Rheumatol Int 2002; 21: Chou CT, Huang CM. Changes in the clinical and laboratory features of lupus patients after the big earthquake in Taiwan. Lupus 2002; 11: Huang CM, Lin TH, Wang HJ, Chen CL. Expression of costimulatory molecules CD80 and CD86 in T cells from patients with SLE. M Taiwan J Med 2002; 7: Huang CM, Tsai FJ, Wu JY, Wu MC. IL-1 and IL-1Ra gene polymorphisms in RA. Scan J Rheumatol 2001; 30: Huang CM. Gouty arthritis in a female patient with mixed connective tissue disease. Clin Rheumatol 2000; 19: Huang CM, Chen CL. Elevated IL-10 levels correlated with disease activity in systemic lupus erythematosus. M Taiwan J Med 2000; 5: Huang WH, Huang CM. Group G streptococcal pyomyositis. J Rheumatol (ROC) 2000; 15: Huang CM, Chen CL, Lin TH, wang HJ. Detection of tumor necrosis factor and receptors in the serum and synovial fluid of patients with RA and OA. M Taiwan J Med 1999; 4:

6 44. Yeh CC, Yang CC, Chen CC, Kao MT, Huang CM, Chou CT, Chang WS, Chen WG, Lu HF, Wu HC. Renal transplantation at a Medical center in Taiwan. M Taiwan J med 1999; 4: Huang CM, Chou CT, Lin TS, and Wang HJ. Osteocalcin in patients with RA in one year followup study. M Taiwan J Med 1998; 3: Huang CM, Chou CT, Chen HT, Jim YF. Septic arthritis following chicken-bite. Clin Rheumtol 1998; 17: Lau SM, Chou CT, Huang CM. Unilateral sacroilitis as an unusual complication of Acupuncture. Clin Rheumtol 1998; 17: Huang CM, Chou CT. Hyperprolactinemia in SLE. Chin Med J (Taipei) 1997; 59: MI 49. Huang CM, Chou CT. Rheumatoid factor in patients with systemic lupus erythematosus. Med J CMCH 1997; 2: Huang CM, Chou CT, Lin CJ, Chu KC. SLE with tuberculous arthritis -- a case report. Med J CMCH 1996; 1: Huang CM, Chou CT, Chen ZZ Blood and urine lead levels in patients with gouty arthritis. J Rheumatol ( ROC ) 1993; 10: Huang CM, Chou CT. The relationship between infection and disease activity in SLE. Chin Med Coll J 1992; 1: Huang CM, Chou CT, Yiu YL. Abduction nerve paralysis in patient with SLE a case report. J Rheumatol ( ROC ) 1992; 9:

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