GLUCOSAMINE SP TABLETS

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1 Executive Executive Summary Summary GLUCOSAMINE SP TABLETS WHAT IS GLUCOSAMINE? Glucosamine is widely used in Europe and is popular as a health food ingredient in Japan. Glucosamine is originally produced by the human body and plays a central role in the health of all joints. Other than the glucosamine, this product contains Methyl Sulfonyl Methane (MSM), Collagen and Shark Cartilage all effective for the strengthening of joints. MSM benefits a range of health problems including painful joints. 1

2 GLUCOSAMINE SP Tablets Explanation of Ingredients Glucosamine is produced naturally in the body, yet there are no major food sources of this substance. Glucosamine is vital for building cartilage. Cartilage is a flexible, tough connective tissue found in several areas of the body. This fine, rubbery tissue functions as padding, a cushion for bones and joints. Benefits > This product has 1,752mg of glucosamine per suggested daily amount of 12 tablets > Fish collagen and other ingredients like hyaluronic acid will rejuvenate your skin from inside > It is designed to relieve inflammation and muscle aches. Recommended for > For all people suffering from joints and ligaments pain > For all people suffering from osteoarthritis of the knee > For all people who want clean veins and smooth blood circulation. Details > Presentation: Glass bottle > Packaging: 360 tablets > Suggested Intake: 6 to 12 tablets > Type: Joint tablets Ingredients > Glucosamine (extracted from crabs and shrimps) > Shark Cartilage Extract (containing chondroitin) > Fish Collagen Peptide > MSM, Devil s Claw Extract > Crystalline Cellulose > Milk Sugar > Sucrose Fatty Acid Ester Red iron oxide > Purified water 2

3 Index SR. NO. ITEMS PAGE NO. REMARKS 1 Explanation/Information about the Product 2 Benefits 5 3 Recommended For 6 4 Ingredients: Short Explanation of Main Ingredients 7 5 OEM Details 8 6 How it Works 9 7 Pictures 10 8 Research Report

4 Information Glucosamine Tablets SP (For Arthritis and Knee Joints Pain Relief Tablets) Glucosamine is a natural chemical compound found in the body. As a supplement, glucosamine is most often used to try to ease the knee joint pain caused by arthritis. Since glucosamine is usually derived from the shells of shellfish while the allergen is within the flesh of the animals, it is probably safe even for those with shellfish allergy. However, many manufacturers of glucosamine derived from shellfish include a warning that those with a seafood allergy should consult a healthcare professional before taking the product. Alternative, non-shellfish derived forms of glucosamine are available. Glucosamine, an amino sugar, is thought to promote the formation and repair of cartilage. Glucosamine sulfate and chondroitin sulfate are components of cartilage. They are the building blocks to make new collagen and proteo-glycans. Since these supplements stimulate the production of new cartilage components, the supplements help the body repair damaged cartilage. Glucosamine is naturally present in the shells of shellfish, animal bones, bone marrow and fungi. Chondroitin sulphate is a chemical that is normally found in cartilage around joints in the body. Chondroitin sulphate is used for osteoarthritis. It is often used in combination with other products, including manganese ascorbate, glucosamine sulphate, glucosamine hydrochloride, or N-acetyl glucosamine. People use chondroitin sulphate for heart disease, weak bones (osteoporosis), and high cholesterol. Chondroitin sulphate is a biomolecule which has increasingly focused the interest of many research groups due to its antioxidant activity. Chondroitin sulphate is also used in a complex with iron for treating iron-deficiency anemia. 4

5 Benefits Glucosamine supplements are most commonly taken by people suffering from osteoarthritis, inflammatory bowel disease (IBD) and ulcerative colitis Glucosamine supplements may help patients with osteoarthritis (OA), specially OA of the hip or knee Glucosamine reduce swelling in the joints and stiffness Glucosamine may also be beneficial for healing muscle and tendon injuries and glaucoma Shark cartilage is a dietary supplement made from the dried and powdered cartilage of a shark which may reduce swelling and inflammation along with pain Shark cartilage is also used for arthritis, psoriasis, wound healing, damage to the retina of the eye due to diabetes, and inflammation of the intestine (enteritis) Collagen is critical for the health of joints, cartilage, tendons, bones, and all connective human tissue Fish collagen helps in health of joints for men and women regardless of their active or passive lifestyle Devil's claw used, also relieves pain like arthritis, gout, muscle pain (myalgia), back pain, tendonitis, chest pain, gastrointestinal (GI) upset or heart burn, fever, and migraine headache. 5

6 Recommended For Those who are suffering from symptoms of osteoarthritis, particularly of the knee Those who wish to maintain current bone health Those who are athletic or play sport Those who suffer from back pain, muscle pain etc. Those who suffer from bone diseases (Kashin-Beck disease) 6

7 Ingredients Active Ingredients Glucosamine (extracted from crabs and shrimps) Shark Cartilage Extract (containing chondroitin) Fish Collagen Peptide MSM, Devil s Claw Extract Crystalline Cellulose Milk Sugar Sucrose Fatty Acid Ester Explanation of Main Ingredients Glucosamine: Glucosamine from Japan is a compound found naturally in the body, made from glucose and the amino acid glutamine. Glycosaminoglycan, a molecule used in the formation and repair of cartilage and other body tissues is produced by Glucosamine. Since the production of glucosamine slows with age, in osteoarthritis, cartilage -- the rubbery material that cushions joints -- becomes stiff and loses its elasticity. This makes the joint prone to damage and may lead to pain, swelling, loss of movement and further deterioration. Taking glucosamine as a nutritional supplement is thought to help repair damaged cartilage by augmenting the body's supply of glucosamine and possibly slow the progression of osteoarthritis. Glucosamine is sometimes combined with methyl sulfonyl methane, or MSM, in nutritional supplements. Other conditions for which glucosamine is used include rheumatoid arthritis and inflammatory bowel disease (Crohn's disease and ulcerative colitis). Chondrotin: Chondroitin, a carbohydrate, is a cartilage component that promotes water retention and elasticity and to inhibit the enzymes that break down cartilage. Both compounds are manufactured by the body. Chondroitin supplements are generally made from cartilage. Chondroitin is the most abundant glycosaminoglycan in cartilage and is responsible for the resiliency of cartilage. Devil s Claw: Japan based Devil s Claw is an herb. It is used to relieve pain like arthritis, gout, muscle pain (myalgia), back pain, tendonitis, chest pain, gastrointestinal (GI) upset or heart burn, fever, and migraine headache. Some people apply devil s claw to the skin for injuries and other skin conditions. 7

8 OEM Details OEM Packaging Ideal MOQ Price Ideal qty. for Sample Order Samples Standard Certificates Type Brand Shelf Life Origin Details 360 tabs/bottle, 3bottles/pack 1,250 bottles On request 3 bottles Available Ingredients list, Formulation list, Packaging details, COA, COO, and Free Sale Certificate Tablets form (Additionally we can also provide in Drink form i.e. Glucosamine Drink) OEM / Private Label (We are very flexible in changing formulation, packaging and designing.) 24 Months Made in Japan 8

9 How It Works Why do people take glucosamine? Glucosamine is so widely used as a supplement that it almost needs no introduction Glucosamine is a substance found naturally in our body that helps maintain healthy joint cartilage, there is some proof that supplementing this substance may help to reduce symptoms linked with osteoarthritis Glucosamine sulphate tablets can be taken on a daily basis to maintain the health of the joints, particularly for knee health Glucosamine helps to keep the cartilage in joints healthy. Natural glucosamine levels drop as people age, this can lead to gradual deterioration of the joint Glucosamine is a non-prescription dietary supplement that is being promoted for its ability to ease osteoarthritis symptoms, which may occur with aging as our joints undergo 'wear-andtear' Glucosamine has also been used to treat rheumatoid arthritis and other conditions, such as inflammatory bowel disease, asthma, allergies, chronic venous insufficiency, sports injuries, chronic low back pain, and many others. 9

10 Pictures Product Image\ Product Packaging Details Japan domestic label for 360 tablets per box (Private brand can be made as per your label) 10

11 Research Report Glucosamine and Chondroitin Glucosamine is a popular supplement for treating and preventing chronic joint pain. It s usually derived from shellfish. It works because it supplies proteoglycans, which are precursors of the synthesis of connective tissue. While some medical studies have sought to discredit the effectiveness of glucosamine, other studies, coupled with anecdotal evidence, show that it works. Glucosamine and chondroitin have been widely promoted as a treatment for osteoarthritis. Glucosamine, an amino sugar, is thought to promote the formation and repair of cartilage. Glucosamine is a popular supplement for treating and preventing chronic joint pain. Glucosamine supplements typically are made from protein found in the shells of shrimp, crab and other shell fish. Some research shows that glucosamine supplements relieve pain in some people with osteoarthritis of the knee. Osteoarthritis also called degenerative joint disease is most common type of arthritis. 11

12 Research Report Arthritis is a degenerative disease in the joints, causing pain, inflammation and limitation of movement. Osteoarthritis is one of the most widespread types of arthritis. It affects the body by wearing down the cartilage between the joints. Although there is no known cure for this disease, many people have been turning to supplements in an effort to relieve the pain and hopefully slow the effects of osteoarthritis. Glucosamine and Chondroitin are both naturally occurring substances in the body. Glucosamine affects the cartilage by being one of the major "building blocks" for the large molecules in cartilage called proteoglycans. These proteoglycans attract and hold the water necessary to lubricate the cartilage, which in turn acts as a cushion between the bones. Chondroitin is a molecule shaped like a long chain. The chain acts as a "sweeper" to bring nutrients into the proteoglycans, giving it the "elasticity" needed for joint movement. It also acts somewhat as a preventative against certain enzymes that would break down the cartilage that leads to the pain and inflammation of bone rubbing against bone. Glucosamine and Chondroitin supplements are used in replace of traditional over the counter pain medications (i.e. aspirin and ibuprofen) for relief, and as an anti-inflammatory treatment to help increase mobility. Glucosamine and Chondroitin: A Powerful Combination for Joints Osteoarthritis is a painful degenerative disease of the cartilage and adjacent bone of joints. Most elderly people are afflicted to some extent, while younger people are also at risk, especially if they have suffered joint trauma, have had repetitive use of certain joints due to occupation or lifestyle, or if they are obese. However, in recent years two naturally occurring supplements glucosamine and chondroitin have become increasingly popular as the treatment of choice for many people. Both of these substances are found naturally in the human body: glucosamine is an amino sugar that stimulates the formation and repair of cartilage; chondroitin is a carbohydrate that promotes elasticity and prevents other enzymes from degrading joint cartilage. 12

13 Research Report There are many published studies which reported a similar level of pain relief obtained from glucosamine and chondroitin to that attainable from medication such as aspirin and ibuprofen. Some research also indicates that the supplements might be able to slow down the rate of further cartilage damage. But the really great news is that no study has so far found any serious side effects from either of these natural products. Glucosamine is present in almost all human tissue and is highly concentrated in our cartilage and connective tissues Glucosamine has been researched and studied continuously over the last 40 years with the majority of studies agreeing glucosamine is necessary for the building and repair of cartilage. Its key benefits include reducing pain and improving mobility for sufferers of osteoarthritis and rheumatoid arthritis. Glucosamine may also be beneficial for healing muscle and tendon injuries and glaucoma. Chondrotin is believed to enhance the shock-absorbing properties of collagen and block enzymes that break down cartilage. Studies are being done to evaluate the ability of chondrotin to reverse cartilage loss. It generally takes two to four months to work completely. Methyl Sulfonyl Methane MSM, Devil s Claw Extract has shown benefits for a range of health problems including arthritis, muscle and joint pain. MSM has shown promise in the inhibition of pain impulses along nerve fibers, lessening of inflammation, increasing blood supply, reducing muscle spasms, and softening of scar tissue. MSM supports healthy, active lifestyle and benefits multiple structures and functions with the body, including connective tissues and the respiratory system while the methyl groups support energy production. Osteoarthritis Osteoarthritis is a major cause of pain and disability. It s a condition where there s loss or damage of cartilage tissue in the joints, and it most commonly affects hips, knees, hands and the spine. Wear and tear is a major cause, so older people are more likely to suffer from osteoarthritis. 13

14 Research Report Wear and tear is a major cause, so older people are more likely to suffer from osteoarthritis. Osteoarthritis can t be cured (other than by replacing the affected joint with a prosthesis) but there are various things you can do to reduce its impact and there are medications to reduce the pain and swelling. Note: More information on Research and Analysis can be provided on request. Disclaimer: The information displayed herein has not been evaluated and/or approved in any form by the Japan Ministry of Health, FDA and/or similar body in Japan or elsewhere. Please follow a balanced life-style, diet and exercise for general health and wellness. None of our products is intended to diagnose, treat, cure or prevent any disease or condition. Consult your doctor at all times. The information provided here is for informational purposes and we do not claim ownership thereof unless indicated otherwise. 14

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