9:30 11:00 Redefining Treatment Expectations in Moderate-to-Severe Psoriasis Room: Macdonald ABCD, Fairmont Chateau Whistler Resort

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1 Thursday, October 26, :30 11:00 Redefining Treatment Expectations in Moderate-to-Severe Psoriasis Session Objectives: Dermatologists participating in this symposium will: Discuss practical management issues with biologic agents in the treatment of psoriatic disease based on extensive US experience, Recognize the key safety issues with TNF antagonists currently available in Canada, Obtain pearls on how to incorporate biologics into their own practice through an interactive panel discussion Faculty: Dr. Kim Papp, Chair Dr. Brian Feagan Dr. Kristian Reich Dr. Kam Shojania Dr. Norman Wasel Agenda: 9:30am 9:35am Welcome Kim Papp, MD Chair 9:35am 10:00am The Use of TNF Blockers in Chronic Inflammatory Disease: What are the Important Safety Issues? Brian Feagan, MD 10:00am 10:15am Changing Paradigms in Moderate-to-Severe Psoriasis 10:15am 10:40am Unmet Needs of Psoriasis and the Promise of Biologics 10:40am 10:55am Remicade Infusion Network: Experience in the Rheumatology Community 10:55am 11:00am Closing Remarks Norman Wasel, MD Kristian Reich, MD Kam Shojania, MD Kim Papp, MD - Chair

2 Thursday, October 26, :00 3:30 From Trial to Clinic: A Year of Raptiva Experience in Canada Session Objectives: Following this workshop, the attendee will be able to: Define the appropriate patients for biological agents Apply practical considerations in the use of biologics for the treatment of psoriasis, with a focus on Raptiva Review the efficacy and safety of Raptiva as observed in Canadian clinical practice Faculty: 1. Charles Lynde, MD FRCPC Chair/Moderator, Intro & Close 2. Richard Langley MC FRCPC Raptiva: Suitable for a Wide Range of Psoriasis Patients 3. Norm Wasel, MD FRCPC Clinical Cases With Raptiva (Canadian Perspective) 4. Kim Papp, MD PhD FRCPC Expert Panel Discussion Program: Clinical use of biologic therapies is changing the way dermatologists are treating moderateto-severe psoriasis. As physicians gain experience with these agents, they are learning practical tips on which agents are best for which patients and why, and on how to optimally use each agent. This program is directed to the practicing dermatologist who treats patients with moderate to severe psoriasis. Topics covered will discuss: How to select an appropriate agent for a patient (with a focus on selecting patients appropriate for treatment with Raptiva) based on different patient profiles Practical guidelines for treating patients with Raptiva, using Canadian case histories.

3 Thursday, October 26, :00 5:45 Plenary Session 1 Chair: Dr. Richard Thomas 4:00 4:05 Opening Remarks Dr. Richard Thomas 4:05 4:25 Update on Topical Therapies of Psoriasis Dr. John Koo 4:25 4:45 Efalizumab for Patients with Palmoplantar Psoriasis 4:45 5:05 Adalimumab in Psoriasis: CHAMPION Phase III Trial Results 5:05 5:25 Cosmeceutical Advances the Latest Approaches to Decrease Unwanted Pigmentation Dr. Richard Langley Dr. Richard Langley Dr. Alexa Kimball 5:25 5:45 Panel and Questions

4 Friday, October 27, :30 11:00 New Advances in Photobiology and Photoprotection Room: Frontenac C, Fairmont Chateau Whistler Resort Session Objectives: Dermatologists participating in this symposium will : have an update of the skin damages caused by UVA radiation recognize the importance of UVA protection and the need for sunscreens with broad spectrum UVA/UVB protection acquire knowledge of UVA protection evaluation with PPD ( Persistent Pigment Darkening ) method evaluate the efficacy of different sunscreens formulations and the benefits of the new filter Mexoryl XL Faculty: Dr Jason Rivers, Chair Dr Robert Bissonnette Anny Fourtanier, L'Oreal Recherche Dominique Moyal, L'Oreal Recherche Jean Louis Refregier, L'Oreal Recherche Agenda: ULTRAVIOLET RADIATION: PUBLIC HEALTH CONCERNS. J.K. Rivers Department of Dermatology, University of British Columbia, Vancouver UPDATE ON UVA INDUCED SKIN PHOTODAMAGE A. Fourtanier -L Oréal Recherche, Clichy, France IMPORTANCE OF UVA PROTECTION: SKIN CANCER AND BEYONG. R. Bissonnette MD, FRCPC Innovaderm Research, Montreal UVA PHOTOPROTECTION EVALUATION D. Moyal, L Oréal Recherche, France NEW ADVANCES IN SUN CARE PRODUCTS: IMPROVED UVA PROTECTION WITH MEXORYL XL J.L. Refregier, Development Director for Sun Care Products, International Applied and Development Research, L Oreal

5 Friday, October 27, :30 1:30 Biologics and Psoriatic Disease: Practical Management Issues and Clinical Update Session Objectives: Dermatologists participating in this symposium will; Discuss practical management issues with biologic agents in the treatment of psoriatic disease based on extensive US experience, Recognize the key safety issues with TNF antagonists currently available in Canada, Obtain pearls on how to incorporate biologics into their own practice through an interactive panel discussion Faculty: Richard Thomas, MD (Vancouver, British Columbia) Joseph Jorizzo, MD (Winston-Salem, North Carolina) Richard Langley, MD (Halifax, Nova Scotia) Agenda: 11:30 Introduction, Learning Objectives, Pre-Assessment (touchpads) 11:40 Biologics: Practical Management Issues (US Experience) Richard Thomas, MD Joseph Jorizzo, MD 12:20 Safety Update: TNF Antagonists Richard Langley, MD 13:00 Panel Discussion 13:25 Post-Assessment and Closing Remarks 13:30 Adjourn

6 Friday, October 27, :00 5:40 Plenary Session 2 Chair: Dr. Chuck Lynde 4:00 4:20 Objectives for Dermatological Toxicities of anti-egfr Therapies in Cancer 4:20 4:40 New Aspects in the pathophysiology and Treatment of Psoriatic Arthritis 4:40 5:00 Pyoderma Gangrenosum and its Management in :00 5:20 Facial Pigmented Lesions: Diagnosis and Treatment 5:20 5:40 Effects of UVB and UVA on Human Skin Pigmentation and Prevention by Sunscreens Dr. Mario Lacouture Dr. Kristian Reich Dr. Joseph L. Jorizzo Dr. Joël Claveau Dr. Dominique Moyal 5:40 6:00 Panel and Questions 6:00 7:30 Cocktail Reception

7 Saturday, October 28, :00 8:30 Buffet Breakfast 8:30 9:00 Plenary Session 3 Chair: Dr. Harvey Lui 8:30 9:00 Skin Therapy Update Dr. Stuart Maddin 9:00 9:20 The Global Regulatory Village Helpful or Harmful to Patients and Physicians Dr. Gavin Corcoran 9:20 9:30 Panel and Questions 9:30 9:55 Coffee Breaks and Poster Exhibits 10:00 11:25 The Impact of Advocacy on Dermatologists and their Patients 10:00 10:05 Opening Remarks Dr. Harvey Lui - Chair 10:05 10:55 The Need for Advocacy (interactive) Dr. Albert Schumacher 10:55 11:05 Canadian Skin Patient Alliance: Progress Report Mr. Denis Morrice 11:05 11:15 Industry Advocacy: Impact on Access to Treatment 11:30 1:30 Boxed Lunch provided for participants not attending advisory board meetings

8 Saturday, October 28, :00 3:20 Plenary Session 4 Chair: Dr. Jerry Tan 2:00 2:20 The Management of Hair Disorders in Women: Too Much Too Little 2:20 2:40 Topical Calcineurin Inhibitors Where Do We Stand Dr. Jerry Shapiro Dr. Alan Fleischer 2:40 3:00 Elidel EADV 2006 Update Dr. Kirk Barber 3:00 3:20 Panel and Questions 3:20 3:45 Coffee Breaks and Poster Exhibits 3:45 4:20 Plenary Session 5 Chair: Dr. Jan Dutz 3:20 3:40 Dead Lice Don't Lay Eggs" - A Product Development Story 3:40 4:00 The Skin as a site of initiation of systemic Autoimmune disease: new opportunities for Treatment Dr. Bill Campbell Dr. Jan Dutz 4:00 4:15 Panel and Questions 4:15 4:25 Closing Comments Dr. Stuart Maddin 4:30 6:30 Closing Reception Room: Frontenac Ballroom, Fairmont Chateau Whistler Resort

9 Sunday, October :30 11:00 Clinical Trial Workshop: Optimizing Your Research Site Room: Macdonald E, Fairmont Chateau Whistler Resort (pre-registration required, FEE: $150+gst) Directed by: Lynne Bulger, Director Medical Affairs, Barrier Therapeutics Paul Kidson, Director Medical Affairs, LEO Pharma Topics: 1. Site Selection: The CRO Perspective Doug Keller, President, Moncoa Medical Research Inc. Site Selection: The Industry Perspective Todd Georgieff, Senior Manager, Clinical Operations, Abbott Lynne Bulger, Director Medical Affairs, Barrier 2. Multidisciplinary Co-operation: Dermatology and Rheumatology Richard Thomas 3. Keeping Up With the Times: Remote Data Capture Paul Kidson 4. Spreading the Good News: Master Plan for Site Metrics Lynne Bulger and Paul Kidson

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