JORGE MANUEL MERCADO, M.D. Chest Diseases of Northwestern Pennsylvania 3580 Peach Street, Suite 103A Erie, PA Office:

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1 JORGE MANUEL MERCADO, M.D. Chest Diseases of Northwestern Pennsylvania 3580 Peach Street, Suite 103A Erie, PA Office: WORK EXPERIENCE March present Chest Diseases of Northwestern Pennsylvania Pulmonary, Critical care and Sleep Medicine Attending Physician July present April 2010 March 2011 August 2009 March 2011 St Vincent s Hospital Medical Director Medical Intensive Care Unit/Step Down Unit UPMC Horizon Director Pulmonary Department UPMC Horizon Primary Health Network Pulmonary, Critical Care and Sleep Medicine Attending Physician MEDICAL CERTIFICATION September 2006 ABIM Board Certified in Internal Medicine October 2009 ABIM Board Certified in Pulmonary Medicine September 2011 ABIM Board Certified in Critical Care Medicine MEDICAL TRAINING July 2006-June 2009 Drexel University College of Medicine Pulmonary/Critical Care/Sleep Fellowship Program July 2003-July 2006 University of Pittsburgh - UPMC Presbyterian-Shadyside Hospital Internal Medicine Residency Program University of Buenos Aires, School of Medicine Medical Doctor M.D. AWARDS November 2005 American College of Physicians (ACP) Pennsylvania Chapter of Medicine Best Research Award Certificate of Merit November 2004 American College of Physicians (ACP) Pennsylvania Chapter of Medicine

2 Best Research Award Certificate of Merit May 2004 University of Pittsburgh Annual Research Award of the Department of Internal Medicine June 2004 University of Pittsburgh Intern of the year RESEARCH ACTIVITIES Molecular Biology and Genetics in Pulmonary Arterial Hypertension Peter Jones, PhD University of Pennsylvania 2006 July 2007 Controlled randomized single-blinded clinical trial using Angiotech central venous catheters (CVC) to prevent bacterial colonization on short term CVC Drexel University College of Medicine (Sub-investigator) Phase IV randomized double-blinded clinical trial comparing clinical efficacy of linezolid to vancomycin in the treatment of nosocomial pneumonia. Drexel University College of Medicine A 52 week, Randomized, Double Blind, Parallel Group Study Fluticasone Propionate/Salmeterol DISKUS Combination Product (FSC) 250/50 mcg BID and Fluticasone Propionate (FP) DISKUS 250 mcg BID in Treatment of Subjects with Asthma Drexel University College of Medicine Phase II pivotal multicenter multinational randomized double blinded placebo controlled study to evaluate the efficacy of TAK 242 in adults with severe sepsis. Drexel University College of Medicine Sept-Nov 2004 Molecular Biology and Genetics in Idiopathic Pulmonary Fibrosis (IPF) and Adult Respiratory Distress Syndrome (ARDS) Augustine Choi, M.D., Department of Pulmonary/Critical Care University of Pittsburgh April-July 2001 Clinical Research in Adult Respiratory Distress Syndrome Javier Aduen, M.D., Department of Pulmonary/Critical Care Mayo Clinic Jacksonville 1998 Research Assistant in neurotropic viruses J. Berria, M.D. Department of Microbiology University of Buenos Aires

3 A 24-Week, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of GSK573719/GW Inhalation Powder and the Individual Components Delivered Once-Daily via a Novel Dry Powder Inhaler in Subjects with Chronic Obstructive Pulmonary Disease: DB A Phase III, Randomized, Double-blind, Placebo-Controlled Study Evaluating The Efficacy, Safety, and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate Compared With Aclidinium Bromide, Formoterol Fumarate and Placebo for 24- Weeks Treatment in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD): LAC-MD-31. A Long-Term, Randomized, Study of the Safety and Tolerability of a Fixed-Dose Combination of Aclidinium Bromide/Formoterol Fumarate compared with Formoterol Fumarate in Patients With Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD): LAC-MD-32. A 52-week, double-blind, randomized, placebo controlled parallel group study to evaluate the effect of roflumilast 500 μg on exacerbations in severe to very severe COPD patients treated with fixed dose combination LABA/ICS (Advair 250/50 μg or, Symbicort 160/4.5 μg): ROF-MD-07. A Clinical Outcomes Study to compare the effect of Fluticasone Furoate/Vilanterol Inhalation Powder 100/25mcg with placebo on Survival in Subjects with moderate Chronic Obstructive Pulmonary Disease (COPD) and a history of or an increased risk for cardiovascular disease: HZC SUMMIT. Novartis Pharmaceuticals trial entitled: A randomized, placebocontrolled, dose-ranging, multi-centre trial of QAW039 (1-450 mg p.o.) to investigate the effect on FEV 1 in and ACQ patients with moderate-to-severe, persistent, allergic asthma, inadequately controlled with ICS therapy: CQAW039A2206. A Phase III, Long-Term, Randomized, Double-Blind, Extension Study of the Efficacy, Safety and Tolerability of Two Fixed Dose Combinations of Aclidinium Bromide/Formoterol Fumarate, Aclidinium Bromide, Formoterol Fumarate and Placebo for 28- Weeks Treatment in Patients with Moderate to Severe, Stable Chronic Obstructive Pulmonary Disease (COPD): LAC-MD-36. A randomized, double blind, parallel group study to assess the efficacy and safety of 12 weeks of once daily, orally inhaled, coadministration of olodaterol 5µg (delivered by the Respimat Inhaler) and tiotropium 18µg (delivered by the HandiHaler ) compared to once daily, orally inhaled, co-administration of placebo (delivered by the Respimat Inhaler) and tiotropium 18µg (delivered by the HandiHaler ) in patients with Chronic Obstructive Pulmonary Disease (COPD):

4 PUBLICATIONS Jorge M. Mercado MD, Lawrence McDermott, MD. Drexel University College of Medicine, Philadelphia, Pennsylvania. TNF DIRECTED APPROACHES FOR RESPIRATORY DISEASES Hansel et al. New drugs and targets for Respiratory diseases. Prous Science. UNDER REVISION Jorge M. Mercado MD, D. Michael Elnicki MD, Phillip Olhaussen, MD, Yoshiko Ogawa, MD, Alessandro Rinaldo, PhD; Asher Tulsky MD. University of Pittsburgh, Pittsburgh; Norwalk Hospital, Norwalk; Beth Israel Medical Center, New York. NIGHTFLOAT FACTS DATA RECOLLECTION OF A NIGHTFLOAT ROTATION UNDER REVISION EFFECTS OF INTRAOPERATIVE FLUID IN THE DEVELOPMENT OF EARLY PULMONARY EDEMA AFTER LIVER TRANSPLANTATION. Javier Aduen, MD; Wolff Stapelfeldt, MD; Charles Burger, MD; Howard Jolles, MD; Jorge Mercado, MD; Stephen Grinton, MD; Gavin Divertie, MD and Margaret Johnson, MD. Pulmonary and Critical Medicne. Mayo Clinic, Jacksonville, Florida; Anesthesiology, Mayo Clinic, Jacksonville, Florida; Radiology, Mayo Clinic, Jacksonville, Florida and Anesthesiology and Critical Care, Mayo Clinic, Jacksonville, Florida. CHEST, October 2002 SUPPLEMENT. Page 113S. PULMONARY ARTERIAL HYPERTENSION AND ITS RELATIONSHIP WITH EARLY PULMONARY EDEMA AFTER LIVER TRANSPLANTATION Javier Aduen, MD; Wolff Stapelfeldt, MD; Margaret Johnson, MD; Jorge Mercado, MD; Stephen Grinton, MD; Gavin Divertie, MD and Charles Burger, MD. Pulmonary and Critical Care Medicine, Mayo Clinic, Jacksonville, Florida; Anesthesiology, Mayo Clinic, Jacksonville, Florida and Anesthesiology and Critical Care, Mayo Clinic, Jacksonville, Florida. CHEST, October 2002 SUPPLEMENT. Page 113S-114S ORAL PRESENTATIONS & POSTERS June 2008 The Laennec Society of Philadelphia A twist of Lyme, Mercado JM Oral Presentation November 2005 American College of Physicians (ACP), Pennsylvania Chapter of Internal Medicine An Uncommon Complication of Chronic Obstructive Pulmonary Disease Mercado, JM, Muddana V, Javed, A, Cooper, A. Variables Associated with Complications from Gastrointestinal Endoscopic Procedures Muddana, V, Mercado, JM, Arnold, G. Development of an Insulin Sliding Scale Protocol Night Float Study Mercado, JM, Cooper, A

5 May 2005 November 2004 American Thoracic Society, International Conference San Diego, CA Evaluation of Plasma Cytokines in ALI/ARDS and Septic Patients Sethi, JM, Mercado, JM, Lucht, LA, Donahoe, M, Choi, AMK, and Zhang, Y ACP Pennsylvania Chapter of Internal Medicine Nightfloat An intern s experience Mercado J.M., MD; Tulsky A., MD May 2004 March 2004 Society of General Internal Medicine (SGIM), National Meeting Chicago, IL Night float An intern s experience Mercado J.M., MD; Tulsky A., MD SGIM Mid-Atlantic Regional Meeting Philadelphia, PA Night float An intern s experience Mercado J.M., MD; Tulsky A., MD Proton Pump inhibitors induced thrombocytopenia Mercado J.M., MD; Tulsky A., MD 6-Thioguanine induced nodular regenerative hyperplasia in a patient with ulcerative colitis and normal liver function tests Mercado J.M., MD; Arnold G., MD US MEDICAL ELECTIVES 2001 The William J. Harrington Training Program for Latin America University of Miami Pediatric Cardiology, Trauma Surgical ICU, Internal Medicine Mayo Clinic, Jacksonville Campus Cardiovascular Diseases Service Wards and Echo lab, Pulmonary Service MICU and Research MEMBERSHIPS SCCM (Society of Critical Care Medicine) ACCP (American College of Chest Physicians) ATS (American Thoracic Society) ACP (American College of Physicians) SGIM (Society General Internal Medicine) AMA (American Medical Association)

6 COMMUNITY SERVICES Birmingham Clinic Medical attention to underserved population of South 2004 Pittsburgh, PA 1997 Buenos Aires City Health Department Lectures on HIV prevention to high school students and community on behalf of the Ministry of Health 1997 Vaccination Campaign to underserved population of Buenos Aires, Argentina TEACHING EXPERIENCE 2009 Present Pulmonary and Critical Care Lectures to Residents and LECOM medical students UPMC Horizon Pulmonary and Critical care Lectures to DUCOM medical students Drexel University College of Medicine (DUCOM) Teaching Assistant, University of Buenos Aires Virology Renal Physiology Clinical Pharmacology ADDITIONAL INFORMATION Interests Fluent in Spanish, English, Italian Basic knowledge of Portuguese, German Hobbies include literature, impressionist painting, music, opera, and sports Revised 1/13