MANUFACTURING PROBLEMS AS OF 15th February 2016

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1 MANUFACTURING PROBLEMS AS OF 15th February 2016 Drug Manufacturer Brand Name Comments Suggested Aciclovir 3% Eye Ointment 4.5gram Zovirax Out of stock - not due until end of March 2016 Amoxycillin powder for Injection 1gram x 10 Amoxycillin powder for Injection 500mg x 10 Amoxycillin & Clavulanic 600mg vials x 10 Amoxil Out of stock - not due until end of May 2016 Amoxil Out of stock - not due until end of January 2016 Augmentin Out of stock - Until further notice Bimatoprost 0.3% in 1ml eye drops Allergan Lumigan Discontinued in July Latanoprost & Travoprost if appropriate as per advice from opthalmology dept DGRI Latanoprost & Travoprost if appropriate as per advice from opthalmology dept DGRI Cardura XL 4mg Pfizer n/a Out of stock - No date as yet Creon capsules Abbott Healthcare Creon Raw material problem. No date. Change to standard release if approved by GP Abbott recommend use of 25,000 capsules conversion chart available.??

2 Cyclizine 50mg in 1ml Injection x 5 Amco Amdipharm Mercury n/a Available from wholesalers again Difflam Cream Meda n/a Out of stock - no date Dipipanone 10mg & cyclizine 30mg Amco Amdipharm Mercury Diconal Out of stock - until at least middle of February Duac Once daily 25g & 50g n/a Pack size changed to 30g & 60g Flecainide 50mg Meda Tambocor Out of stock - Until March 2016 Flecainide 100mg Meda Tambocor In stock again Havrix Hepatitis A (Inactivated) vaccine Out of Stock - end of January 2016 See Nostrum advice Use Avaxim formulary choice Havrix vaccine x 10 PFS Havrix Junior Out of stock - End of January 2016 Out of stock - End of January 2016 Use Avaxim formulary choice Use Vaqta paediatric Havrix Junior vaccine x 10 PFS Out of stcok - End of January 2016 Use Vaqta paediatric Hepatitis A (Inactivated ) & hepatitis B (Rdna) vaccine Twinrix Adult & X 10 PFS Limited stock - until further notice Hormonin Tablets Amco n/a Discontinued Use Ambirix - Hep B not available on the NHS for travel purposes Consult GP for alternative HRT therapy

3 Insulin Basal solostar 100units in 1ml pre-filled pen Insulin Basal 100units per 1ml cartridge Insulin Comb units in 1ml cartridge Insulin Comb Solostar 100unit in 1ml pre-filled pen Sanofi n/a Out of stock - Until July 2016 Ipratropium Bromide Nebules 2ml Respontin Out of stock - Until further notice Lacri-lube eye ointment Allergan n/a Ovestin cream Aspen Pharma n/a Delay from America where manufactured - 3.5g due Mi9d to Late February - 5g due Mid to Late February Due back in stock with manufacturers 16th January - May take a few days to filter into wholesalers

4 Pioglitazone All Strengths Ongoing shortage - Where available will now cost 33 to 40 per month Podophyllotoxin Cream 0.15% x 5g Warticon Out of stock - until end of January 2016 Potassium Chloride 600mg SR Tablets Alliance Pharma Slow K Out of Stock - not due until Quarter Use Liquid or Salicylate prep Premique Low Dose Pfizer n/a Out of stock -No date as yet Pulvinal Beclomethasone Inhalers - All strengths Chiesi n/a Discontinued Pulvinal Salbutamol Chiesi n/a Discontinued Quinaderm 5% cream Alliance Pharma N/A Raw material problem - Likely to last until 2016 Ranitidine 150mg Tablets x 60 Zantac Out of stock - Until Further Notice Ranitidine 300mg Tablets x 30 Zantac Out of stock - Until Further Notice Ranitidine Syrup Zantac Out of stock - until further notice Ranitidine Injection 25mg in 1ml x 5 x 2ml Zantac Out of stock - Until further notice Ropinirole prolonged release 2mg Requip Limited stock- likely to last until end of January 2016 Ropinirole prolonged release 4mg Requip Limited stock- likely to last until end of January 2016 Ropinirole prolonged release 8mg Requip Limited stock- likely to last until end of January 2016 Salbutamol Easyhaler Orion n/a Manufacturers advise back in stock with wholesalers w/c 18th January Vita-Pos scope Opthalmics n/a Out of stock - Next delivery date is March 2106 switch to generic switch to generic Xailin Night Nicox Pharma n/a available from AAH, Pheonix & Alliance wholesalers Xailin eye gel Nicox Pharma n/a Dispatched from France 14th January- should filter into wholesalers after a couple of weeks

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