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1 araq-491-tio Sper,fr-rzhv Pirori%ttr DIRK MARCEL DHOSSCH E LORNA WIN G MASATAKA OHTA KLAUS-JÜRGEN NEUMÄRKER

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3 CONTRIBUTORS ACKNOWLEDGMENTS PREFACE xiii xv xvii SECTION I CLASSIFICATIO N Classification Matters for Catatonia and Autism in Children KLAUS-JÜRGEN NEUMARKER I. Introduction 3 II. Catatonia 4 III. Autism 10 IV. Autism and Catatonia 12 References 1 4 A Systematic Examination of Catatonia-Like Clinical Picture s in Autism Spectrum Disorders LORNA WING AND AMITTA SHAH I. Introduction 22 II. Clinical Features of ASDs and Catatonia 23 III. Manifestations of Catatonic Features in ASDs 2 3 IV. Three Studies of Catatonic Features in ASD 24 V. Discussion 3 4 VI. Conclusions 3 7 References 37

4 Catatonia in Individuals with Autism Spectrum Disorders i n Adolescence and Early Adulthood : A Long Ter m Prospective Study MASATAKA OHTA, YUKIKO NANO, AND YOKO NAGA I I. Introduction 42 II. Subjects 43 III. Methods 43 IV. Presentation of Cases 44 V. Results 49 VI. Discussion 5 1 VII. Suggestions on Treatment 52 VIII. Limitation of this Study 5 3 IX. Conclusions 5 3 References 5 3 Are Autistic and Catatonic Regression Related? A Few Workin g Hypotheses Involving GABA, Purkinje Cell Survival, Neurogenesis, and ECT DIRK MARCEL DHOSSCHE AND UJIWAL ROU T I. Introduction 5 6 II. Early Autistic Regression 5 7 III. Late Autistic Regression 5 8 W. Catatonic Regression in Autism 59 V. Are Autistic and Catatonic Regression Related? 61 VI. Theoretical Treatment Implications 62 VII. History of ECT in Childhood Psychoses 63 VIII. GABA in Autistic Regression 64 IX. GABA in Catatonic Regression 66 X. GABA and the Mechanism of Action of ECT 68 XI. ECS in GABA Models of Autism 69 XII. ECS and Purkinje Cell Survival 70 XIII. ECS and Neurogenesis 7 1 References 72 SECTION II ASSESSMEN T Psychomotor Development and Psychopathology in Childhoo d DIRK M. J. DE RAEYMAECKER I. Three Vital Steps in Motor Development 8 4 II. Human Motility: A View From Psychoanalysis 88

5 III. Developmental Psychopathology and Motor Impairment 92 References 99 The Importance of Catatonia and Stereotypies in Autisti c Spectrum Disorders LAURA STOPPELBEIN, LEILANI GREENING, AND ANGELINA KAKOOZ A I. Introduction 104 II. Catatonia and ASD 10 4 III. Stereotypic Movement Disorder 11 0 References 11 5 Prader-Willi Syndrome : Atypical Psychoses and Motor Dysfunction s WILLEM M. A. VERHOEVEN AND SIEGFRIED TUINIER I. Introduction 11 9 II. Development and Behavior 120 III. Psychotic Disorders 12 1 N. Psychomotor Symptoms 126 V. Conclusions 127 References 128 Towards a Valid Nosography and Psychopathology o f Catatonia in Children and Adolescent s DAVID COHEN I. Introduction 13 2 II. Phenomenology of Catatonia in Young People 13 2 III. Towards a Broader Nosography for Child, Adolescent, and Adult Catatonia 135 IV. Models of Catatonia 13 6 V. Psychopathological Model for Catatonia 138 VI. Discussion 143 VII. Conclusions 145 References 146 SECTION II I BIOLOGY Is There a Common Neuronal Basis for Autism and Catatonia? DIRK MARCEL DHOSSCHE, BRENDAN T. CARROLL, AND TRESSA D. CARROLL I. Introduction 151 II. Motor Theory of Language and Autism 152

6 III. Are Autism and Catatonia Neurobiological Syndromes? 15 3 IV. Catatonia as a Neurobiological Syndrome 15 4 V. Autism as a Neurobiological Syndrome 15 6 VI. Is There a Common Neuronal Basis for Autism and Catatonia? 15 7 VII. Future Directions: Parallel Family-Based Studies in Autism and Catatonia 159 VIII. Implications 16 1 References 16 2 Shared Susceptibility Region on Chromosome 15 Betwee n Autism and Catatoni a 'WON C. CHAGNON I. Introduction 16 5 II. Methods 16 6 III. Results 16 7 IV. Conclusions 17 3 References 17 3 SECTION IV TREATMENT Current Trends in Behavioral Interventions for Children with Autis m DOROTHY SCATTONE AND KIMBERLY R. KNIGHT I. Current Trends in Behavioral Interventions for Children with Autism in the United States 181 II. Language 182 III. Social Skills 18 5 IV. Self-Management 189 V. Conclusions 19 1 References 191 Case Reports with a Child Psychiatric Exploration of Catatonia, Autism, and Delirium JAN N. M. SCHIEVELD I. Introduction 195 II. Case Histories 197 III. Methods 199 IV. Results 200 V. Discussion 201

7 VI. Conclusions 20 3 VII. Epicrisis 203 References 204 ECT and the Youth : Catatonia in Contex t FRANK K. M. ZAW I. Introduction 208 II. ECT and the Youth 21 0 III. Indications for ECT 21 3 W. Pre-ECT Consideration 21 7 V. Administration of ECT 21 9 VI. Adverse Effects of ECT 22 1 VII. Concurrent Medication 223 VIII. Mortality 224 IX. Patients' Satisfaction and Attitude to ECT 224 X. What Follows ECT? 225 XI. Conclusions 226 XII. Conflict of Interest 227 References 227 Catatonia in Autistic Spectrum Disorders : A Medica l Treatment Algorith m MAX FINK, MICHAEL A. TAYLOR, AND NEERA GHAZIUDDIN I. Introduction 23 3 II. Catatonia 23 7 III. Treatment Algorithm 239 W. Theory 241 References 242 Psychological Approaches to Chronic Catatonia-Like Deterioratio n in Autism Spectrum Disorder s AMITTA SHAH AND LORNA WING I. Introduction 24 6 II. Effects of Stress 247 III. Effect of Medical Treatments 25 0 W. Problems with Assessing the Effects of Medical Treatments 25 1 V. Psychological Methods of Intervention 25 2 VI. General Principles of Psychological Treatment and Management 25 3 VII. Management of Specific Problems 25 7 VIII. Implications for Services and Staffing Levels 260

8 IX. Conclusions 260 References 263 SECTION V BLUEPRINTS Blueprints for the Assessment, Treatment, and Future Study o f Catatonia in Autism Spectrum Disorders DIRK MARCEL DHOSSCHE, AMIITA SHAH, AND LORNA WING I. Introduction 26 8 II. Blueprint for the Assessment of Catatonia in ASDs 269 III. Blueprint for the Treatment of Catatonia in ASDs 273 W. Blueprint for the Future Study of Catatonia in ASDs 280 References 283 INDEx 285 CONTENTS OF RECENT VOLUMES 297

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