Senior researcher III/ Head of Research Psychiatry Laboratory Alexandru Obregia Clinical Hospital of Psychiatry

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1 Europass Curriculum Vitae Personal information First name(s) / Surname(s) Magdalena Budisteanu Address(es) 1 Veronica Micle St., Bucharest, Romania Telephone(s) Mobile: Fax(es) magda_efrim@yahoo.com Nationality Romanian Date of birth Gender female Work experience Researcher Research activities and clinical diagnostic in neuropediatric disorders. Coordinator / Person in charge of 4 national research projects Alexandru Obregia Clinical Hospital of Psychiatry, Berceni St., Bucharest, Romania Research, diagnosis present Senior researcher III/ Head of Research Psychiatry Laboratory Alexandru Obregia Clinical Hospital of Psychiatry Director / Responsible of national research projects. Areas of research: Neuropediatrics pathology. Coordinator of a research project entitled Multidisciplinary research clinical, cytogenetic and molecular in mental retardation syndromes associating congenital anomalies: knowledge advances and management improvement, National Research Program PNII, 2008-ongoing. Participant in national and international research projects (Romania-France bilateral cooperation, in framework of Brancusi). Clinical activity, investigation and treatment in children with neurological diseases Teaching - neurogenetics courses for students and doctors of different specialties Alexandru Obregia Clinical Hospital of Psychiatry, Berceni St., Bucharest, Romania Research, diagnosis, teaching present MD, Researcher Participant in national and international research projects (Romania-France bilateral cooperation, in framework of Brancusi). Director / Responsible of national research projects. Laboratory of Medical Genetics Victor Babes National Institute of Pathology, Splaiul Independentei St., Bucharest, Romania Research Page 1/5 - Curriculum vitae of

2 Education and training Level in national or international classification 1995 Medical doctor General medicine University of Medicine, Craiova certified neurologist () Ministry of Health, Romania certified researcher 2008-present Senior pediatric neurologist 2008-present Senior researcher III PhD Carol Davila University of Medicine and Pharmacy, Bucharest Personal skills and competences Mother tongue(s) romanian Other language(s) Self-assessment Understanding Speaking Writing European level (*) Listening Reading Spoken interaction Spoken production German C1 C2 C2 C1 C2 English C1 C1 C1 C1 C1 (*) Common European Framework of Reference for Languages Page 2/5 - Curriculum vitae of

3 Social skills and competences Good communication and teamwork Organisational skills and competences Participant in national and international research projects (Romania-France bilateral cooperation, in framework of Brancusi) national research projects director in 1 project; national research projects responsible in 3 projects. Technical skills and competences Competences : Board-certified in Skills: clinical neurogenetics dysmorphology cytogenetics EEG Other trainings and courses: Romanian-German postgraduate course of medical genetics (Oradea, 2002; Galati, 2011) European Course of Dysmorphology, Rome, Italy 2006, 2008, 2009, 2011 Course of Genetics of Epilepsy - EUREPA European Course of Clinical Dysmorphology, Bologna, Italy 2007 Computer skills and competences MS Office; Adobe Photoshop; Power Point Artistic skills and competences - Other skills and competences - Driving licence - Additional information National nominee in the Management Comitee of the COST Action BM1004: Enhancing the scientific study of early autism: A network to improve research, services and outcomes Member of ESHG, ECA, SRGM (Romanian Society of Medical Genetics), Fellowship for conference attendance at European Human Genetics Conference, Birmingham, 2003, Amsterdam, Fellowship for participation at European Conference of Rare Diseases - Plovdiv, Bulgaria, Fellowship for participation at Course Genetics of Epilepsies organized by EUREPA September 2006 March Member of Scientific Council of Alexandru Obregia Clinical Hospital of Psychiatry Peer-reviewer Neurology, Neurosurgery, Psychiatry Journal, Journal Maedica A Journal of Clinical Medicine Annexes List of publications see below Page 3/5 - Curriculum vitae of

4 Publications Main publications: 1. Atypical presentations of 22q11.2 deletion syndrome: explaining the genetic defects and genome architecture. Andreea Cristina Ţutulan-Cunita, Magdalena Budisteanu, Sorina Mihaela Papuc, Jean- Michel Dupont, Dominique Blancho, Aziza Lebbar, Géraldine Viot, Agripina Lungeanu, Aurora Arghir. Psychiatry Research, doi: /j.psychres , 2012; 2. 3p14 interstitial deletion novel case report and review. A.C. Tutulan-Cunita, S.M. Papuc, A. Arghir, K.M. Rötzer, C. Deshpande, A. Lungeanu, M. Budişteanu. J. Child. Neurol., DOI: / , 2012; 3. Novel clinical finding in MECP2 Duplication Syndrome: a case report, M. Budisteanu, S.M. Chirieac, A. Tutulan-Cunita, B. Budisteanu, A. Arghir. Eur. Child Adolesc. Psychiatry 20: (2011). 4. Cohen syndrome a rare genetic cause of hypotonia in children. Magdalena Budisteanu, Diana Barca, Sorina Mihaela Chirieac, Sanda Magureanu. Maedica A Journal of Clinical Medicine. vol. 5(8), nr 1, p , Oculocutaneous albinism associated with multiple malformations and psychomotor retardation. Magdalena Budisteanu, Aurora Arghir, Sorina Mihaela Chirieac, Georgeta Cardos, Agripina Lungeanu. Pediatric Dermatology 27(2): (2010) q deletion syndrome A case report. Magdalena Budisteanu, Aurora Arghir, Sorina Mihaela Chirieac, Andreea Tutulan-Cunita, Agripina Lungeanu. Maedica A Journal of Clinical Medicine. 5(2): , Microarray-based comparative genomic hybridization (acgh) between basic research and clinical diagnostic. A.C. Tutulan-Cunita, M. Budisteanu, S.M. Chirieac, A. Arghir, G. Cardos, A. Lungeanu. Analele Ştiinţifice ale Universităţii Al.I.Cuza (Iaşi), Sect. Genetică şi Biologie Moleculară, tom XI, 2010, p Chromosome Y Isodicentrics in two cases with ambiguous genitalia and features of Turner syndrome. Lungeanu A., Arghir A., Arps S., Cardos G., Dumitriu N., Budisteanu M., Chirieac S., Rodewald A. Balkan Journal of Medical Genetics, Nr. 12, Vol. 12 (1), Phenotypic Variability In Angelman Syndrome Report Of Two Cases. M. Budisteanu, A. Arghir, G. Cardos, S. Chirieac, Dominique Blanchot, Magureanu S, J-M. Dupont & A. Lungeanu. Maedica, vol. 3 (6), Nr. 3, 2008, Cerebral venous thrombosis in children. The role of early interventions. Magdalena Budisteanu, Carmen Burloiu, Catrinel Iliescu. European Journal of. Volume 12, Supplement 1, May Phenotypic variability in Angelman syndrome report of two cases. M.Budisteanu, A.Arghir, G. Cardos, S.Chirieac, S.Magureanu, D.Blancho, J.-M.Dupont, A.Lungeanu. Maedica A Journal of Clinical Medicine, vol. 3, nr 4, p , 2008; 12. Cytogenetic Abnormalities and Reproductive Failures. Agripina Lungeanu, Adriana Stana, Aurora Arghir, Maria Bari, Magdalena Budisteanu. Maedica, Vol. 2 (5), Nr. 3, 2007, Books Co-author at the books Diagnosis and therapeutic algorithms in Pediatria (V. Popescu (ed): Bucharest, 2001) and (V. Popescu (ed): Bucharest, 2002) Page 4/5 - Curriculum vitae of

5 Conferences and Meetings: over than 70 posters and oral presentations in national and international scientific meetings and conferences, among which: European Society of Human Genetics Conferences, International Congress of Human Genetics, European Cytogenetics Conferences etc Page 5/5 - Curriculum vitae of

PUBLICATIONS. Title: GENETIC TECHNOLOGIES IN CANCER INVESTIGATION APPLICATIONS IN AGGRESIVE LYMPHOID MALIGNANCIES.

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