EURON WORKSHOP DRUGS AND THE BRAIN: FROM LABORATORY TO CLINIC October 1 5, 2019 University of Crete, Heraklion, Crete, Greece

Size: px

Start display at page:

Download "EURON WORKSHOP DRUGS AND THE BRAIN: FROM LABORATORY TO CLINIC October 1 5, 2019 University of Crete, Heraklion, Crete, Greece"

Amberly Ramsey
5 years ago
Views:

EURON WORKSHOP DRUGS AND THE BRAIN: FROM LABORATORY TO CLINIC October 1 5, 2019 University of Crete, Heraklion, Crete, Greece Introduction: In this EURON workshop different topics in relation to

The topics for this event are: NEURODEGENERATION MOOD BRAIN GUT AXIS COGNITION ENHANCEMENT ILLICIT DRUGS The aim of this workshop is to give an up to date overview of the latest developments in these

1 EURON WORKSHOP DRUGS AND THE BRAIN: FROM LABORATORY TO CLINIC October 1 5, 2019 University of Crete, Heraklion, Crete, Greece Introduction: In this EURON workshop different topics in relation to Psychopharmacology will be presented. The topics for this event are: NEURODEGENERATION MOOD BRAIN GUT AXIS COGNITION ENHANCEMENT ILLICIT DRUGS The aim of this workshop is to give an up to date overview of the latest developments in these different research fields. Students will get a better understanding how drugs work in the brain and how drugs can be developed to treat various brain disorders. The five different thematic topics will be accompanied by interactive workshops. In these workshops small groups will discuss a specific topic that relates to the theme on a specific day. This will stimulate active participation in discussions, and is further encouraged by educationally well trained experts, coming from academia and industry. Participants also have the opportunity to present their own research in poster and elevator pitch sessions. One day will be organized in collaboration with the Hellenic Society for Neuroscience (HSfN). The scientific programme will be accompanied by social events. Organization: European Graduate School of Neuroscience (EURON), School for Mental Health and Neuroscience and the Dept. of Neuropsychology and Psychopharmacology, Maastricht University, Maastricht, The Netherlands. In collaboration with the Graduate Program of Neuroscience, University of Crete, Heraklion, Greece, and in conjunction with the Hellenic Society for Neuroscience (HSfN). Organizers: EURON & Maastricht University: Prof. Arjan Blokland, Dr. Gunter Kenis, Prof. Jos Prickaerts, Dr. Nicole Senden University of Crete: Prof. Kyriaki Thermos, Dr. Kyriaki Sidiropoulou Registration: The workshop is open for PhD students, junior post doctoral researchers and also for master students doing an internship in a relevant research field, with a maximum of 50 participants. The registration starts on March 1st, Early bird registration: March 1 July 1 / Late registration: July 1 August 30.

2 Registration fee (incl. accommodation and dinners): Early bird: Euron Members: 350 EUR / Non Euron Members: 450 EUR / Industry: 650 EUR Late registration: Euron Members: 400 EUR / Non Euron Members: 500 EUR / Industry: 700 EUR More information: This workshop qualifies for 2 European credits. Participants will get a certificate of attendance listing the credits. secr.euron@maastrichtuniversity.nl Teaching Content: Lectures by experts in the field Discussion groups on a specific statement, moderated by the experts in the field. Afterwards, each group will give a presentation on their findings during a plenary session. Poster presentations: all participants have to submit an abstract of their research and present a poster. Elevator pitches: 5 minute presentations by participants.

3 PRELIMINARY PROGRAMME Venue: School of Medicine, University of Crete TUESDAY OCT 1 st NEURODEGENERATION Registration Opening, Introduction and General information Prof. Arjan Blokland, Dr. Gunter Kenis and Prof. Kiki Thermos Opening Lecture: The future of depression research: the search for a new generation of antidepressants. Prof. Brian Leonard (National University of Galway, Ireland) Elevator pitches participants (ca. 10 participants) Three expert lectures Cognitive Aging: insights from functional and molecular neuroimaging Prof. Bernard Hanseeuw (UCLouvain, Brussels, Belgium) speaker to be confirmed Alzheimer s Disease and epigenetics Dr. Daniël van den Hove (Maastricht University, The Netherlands) Novel treatments for cognition in Alzheimer s Disease Prof. Jos Prickaerts (Maastricht University, The Netherlands) Joint dinner WEDNESDAY OCT 2 nd NEURODEVELOPMENT mtor in developmental disorders Prof. Martien Kas (Groningen University, The Netherlands) Vasopressin 1a receptor antagonism as a treatment for autism Dr. Barbara Biemans (Roche, Basel, Switzerland) Early SSRI exposure and neurodevelopmental disorders Dr. Jocelien Olivier (Groningen University, The Netherlands) Workshop 1 There are no neurological diseases. Moderator Prof. Harald Schmidt Workshop 2 Neurodevelopment versus neurotransmission: what makes the difference? Moderator Dr. Judith Homberg Workshop 3 Animal models of psychiatric disorders are of minimal relevance for the development of novel psychotropic drugs and have contributed to the lack of significant progress in the therapeutic advance in recent years. Moderator Prof. Arjan Blokland Moderator Prof. Brian Leonard Social activity: sight seeing THURSDAY OCT 3 rd ILLICIT DRUGS Three expert lectures Acute and long term effects of classical drugs of reward and abuse on cognition and social behavior (e.g. alcohol, MDMA, cannabis, cocaine) Dr. Kim Kuypers (Maastricht University, The Netherlands) Acute and long term effects of the new kids on the block (novel psycho active substances) on physiological and behavioral parameters/receptor profiles Dr. Tomas Palenicek (NIMH, Czech Republic) Acute and long term effects of psychedelics and their therapeutic potential Dr. Jordi Riba (University of Barcelona, Spain)

4 Workshop 1 Which type of validity should we trust (more) for translational animal studies? Face, construct or predictive? Moderator Dr. Barbara Biemans Workshop 2 The fake validity of animal models in psychopharmacology. Moderator Prof. Arjan Blokland Workshop 3 Pills are not the future, gene therapy might be. Moderator Prof. Jos Prickaerts Moderator Dr. Gunter Kenis Joint dinner with music FRIDAY OCT 4 th BRAIN GUT Axis and MOOD (integrated in Hellenic Society for Neuroscience Meeting) Depression and food Prof. Nuno Sousa (University of Minho, Braga, Portugal) Understanding the gut brain axis in neuropsychiatric diseases Dr. Gerard Clarke (University of Cork, Ireland) Nutritional neuroscience: food and the brain Dr. Gabriela Bergonzelli (Nestlé, Lasusanne, Switserland) Poster presentations of workshop participants on the HSfN Meeting SATURDAY OCT 5 th CLINICAL DEVELOPMENT OF DRUGS Drug development in pain Dr. John Bothmer (Grünenthal GmbH, Aachen, Germany) CNS drug development: towards mechanistic predictions Dr. Massimo Bani (UCB, Brussels, Belgium) Mechanism based approach to treat disease symptoms Prof. Harald Schmidt (Maastricht University, The Netherlands) Workshop 1 Availability of MDMA assisted psychotherapy should not be limited by the patient s age. Moderator Dr. Kim Kuypers (Maastricht University, The Netherlands) Workshop 2 There is no such thing as an inverted U shape dose response relationship. Moderator Prof. Harald Schmidt (Maastricht University, The Netherlands) Workshop 3 Pain and addiction cannot be dissociated with drug treatment. Moderator Dr. John Bothmer (Grünenthal GmbH, Aachen, Germany) Moderator Prof. Arjan Blokland (Maastricht University, The Netherlands) Evaluation workshop Concluding remarks

5 FACULTY LIST / ORGANIZERS Dr. Massimo Bani, Global Head Clinical Pharmacology, UCB Pharma, Brussels, Belgium Massimo.bani@ucb.com Dr. Barbara Biemans, Laboratory Head Developmental & Behavioral Neuroscience, F. Hoffmann La Roche, Basel, Switzerland barbara.biemans@roche.com Prof. Arjan Blokland, Prof. Section Psychopharmacology,Neuropsychology & Psychopharmacology Departments, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands a.blokland@maastrichtuniversity.nl Dr. John Bothmer, Innovation Unit Pain, Grünenthal GmbH, Aachen, Germany john.bothmer@grunenthal.com Dr. Gerard Clarke, Dept. of Psychiatry, University College Cork, Ireland G.Clarke@ucc.ie Dr. Judith Homberg, Department of Cognitive Neuroscience, Group Behavioural Neurogenetics, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre (RUMC), Nijmegen, The Netherlands j.homberg@cns.umcn.nl Dr. Daniel van den Hove, Associate Professor, Dept. Psychiatry & Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands d.vandenhove@maastrichtuniversity.nl Prof. Martien Kas, Prof. of Behavioral Neuroscience, Facultyof Science and Engineering, Groningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, The Netherlands m.j.h.kas@rug.nl Dr. Gunter Kenis, Director EURON, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands g.kenis@maastrichtuniversity.nl Dr. Kim Kuypers, Ass. Prof. Section Psychopharmacology, Dept. Neuropsychology & Psychopharmacology, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands k.kuypers@maastrichtuniversity.nl Prof. Brian Leonard, Em. Prof. Pharmacology, National University of Galway, Ireland brian@psycholeonard.com Dr. Tomas Palenicek, National Institute of Mental Health, Czech Republic tomas.palenicek@nudz.cz Prof. Jos Prickaerts, Prof. Experimental Neuropsychopharmacology, Dept. Psychiatry & Neuropsychology, School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands jos.prickaerts@maastrichtuniversity.nl Dr. Jordi Riba, Sant Pau Institute of Biomedical Research, Research Group Human Neuropsychopharmacology, University of Barcelona, Spain jriba@santpau.cat Prof. Harald Schmidt, Prof. of Pharmacology, Dept. of Pharmacology and Personalised Medicine, School for Cardiovascular Diseases, Fac. Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands h.schmidt@maastrichtuniversity.nl Dr. Nicole Senden, Programme Coordinator EURON, Maastricht University, Maastricht, The Netherlands secr.euron@maastrichtuniversity.nl Prof. Nuno Sousa, Full Professor, School of Health Science, University of Minho, Braga, Portugal njcsousa@med.uminho.pt Prof. Kyriaki (Kiki) Thermos, Prof. of Pharmacology, School of Medicine, University of Crete, Heraklion, Crete, Greece thermos@uoc.gr

Harry Steinbusch (Maastricht University, NL) - Failures and New Strategies in Drug Treatments for Alzheimer s Disease

Harry Steinbusch (Maastricht University, NL) - Failures and New Strategies in Drug Treatments for Alzheimer s Disease SATURDAY OCT 7 TH - REGISTRATION AND OPENING LECTURE Location: University of Crete Medical School, Amphitheater 7A 08.00-09.00 Registration 09.00-09.30 Arjan Blokland (Maastricht University, NL) & Kiki