TABLE OF CONTENTS. Table of Authorities... iii. Interest of Amicus Scientific Background... 2
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1 TABLE OF CONTENTS Table of Authorities... iii Interest of Amicus... 1 Scientific Background... 2 I. The Benefits and Side Effects of Antipsychotic Drugs... 2 A. Conventional Antipsychotic Drugs... 5 B. Atypical Antipsychotic Drugs... 8 C. Individual Variation in Effects of Antipsychotic Drugs II. Non-Drug Alternatives to Antipsychotic Drugs Summary of Argument Argument I. Forcible Administration of Antipsychotic Drugs to Restore Competence Should Be Permitted Only If It Is Therapeutically Appropriate, Substantially Likely to Restore Competence, and the Least Intrusive Means of Achieving That Purpose A. Forced Administration of the Drug Must be Therapeutically Appropriate B. The Drug Must be Substantially Likely to Accomplish the Goal Justifying its Forced Administration -- Trial Competence -- and Necessary to Achieve that Goal II. The Forced Administration of Antipsychotic Drugs May Also Compromise the Defendant s Fifth and Sixth Amendment Rights to a Fair Trial i
2 A. The Side Effects of Antipsychotic Drugs May Threaten the Defendant s Fair Trial Rights B. The Intended Effect of Antipsychotic Drugs May Undermine the Defense Conclusion ii
3 TABLE OF AUTHORITIES FEDERAL CASES Brady v. Maryland, 373 U.S. 83 (1963) Chambers v. Ingram, 858 F.2d 351 (7th Cir. 1988) Dunn v. Blumstein, 405 U.S. 330 (1972) Dusky v. United States, 362 U.S. 402 (1960)... 3, 13 Jackson v. Indiana, 406 U.S. 715 (1972) Krulewitch v. United States, 336 U.S. 440 (1949) Kulas v. Valdez, 159 F.3d 453 (9th Cir. 1998)... 5 Mills v. Rogers, 457 U.S. 291 (1982)... 5 Palko v. Connecticut, 302 U.S. 319 (1937) Rickman v. Dutton, 864 F.Supp. 686 (M.D. Tenn. 1994) Riggins v. Nevada, 504 U.S. 127 (1992)... passim United States v. Brandon, 158 F.3d 947 (6th Cir. 1998)... 5, 18, 19, 22 United States v. Morgan, 193 F.3d 252 (4th Cir. 1999) United States v. Nichols, 56 F.3d 403 (2d Cir. 1995) United States v. Weston, 206 F.3d 9 (D.C. Cir. 2000)... 25, 28, 29 United States v. Weston, 255 F.3d 873 (D.C. Cir. 2001)... passim Washington v. Harper, 494 U.S. 210 (1990)... passim iii
4 STATE CASES Schloendorff v. Society of New York Hospital, 211 N.Y BOOKS AND ARTICLES Gerard Addonizio, Neuroleptic Malignant Syndrome, in Drug-Induced Dysfunction in Psychiatry 145 (Matcheri S. Keshavan & John S. Kennedy eds., 1992)... 7 Paul S. Appelbaum, Almost a Revolution (1994)... 6 Thomas R.E. Barnes & J. Guy Edwards, The Side-Effects of Antipsychotic Drugs, I. CNS and Neuromuscular Effects, in Antipsychotic Drugs and Their Side-Effects 213 (1993)... 5, 6 Kenneth J. Bender, Injectible Atypical Antipsychotics Recommended, Psychiatric Times, May Peter F. Buckley, The Role of Typical and Atypical Antipsychotic Medications in the Management of Agitation and Aggression, 60 J. Clinical Psychiatry 52 (1999) Glynn et al., Compliance with Less Restrictive Aggression-Control Procedures (1989) Drug-Induced Dysfunction in Psychiatry (Matcheri S. Keshavan & John S. Kennedy eds., 1992)... 5 Kirk Heilbrun et al., The Debate on Treating Individuals Incompetent for Execution, 149 Am. J. Psychiatry 596 (1992)... 12, 13 Philip G. Janicak et al., Principles and Practice of Psychopharmacotherapy (2d ed. 1997)... passim J. M. Kane, Tardive Dyskinesia: Epidemiology and Clinical Presentation, in Psychopharmacology: The 4th Generation of Progress 1485 (F. E. Bloom & D. J. Kupfer eds., 1995)... 6 iv
5 Robert Paul Liberman et al., Psychiatric Rehabilitation, in 2 Comprehensive Textbook of Psychiatry/VI 2696 (Harold I. Kaplan & Benjamin J. Sadock eds., 6th ed. 1995) James B. Lohr, Tardive Dyskinesia, in Drug-Induced Dysfunction in Psychology 131 (Matcheri S. Keshavan & John S. Kennedy eds., 1991)... 6, 10, 11 Robert A. Nicholson & Karen E. Kugler, Competent and Incompetent Criminal Defendants: A Quantitative Review of Comparative Research, 109 Psychol. Bull. 355 (1991)... 3, 13 Paul A. Nidich & Jacqueline Collins, Involuntary Administration of Psychotropic Medication: A Federal Court Update, 11 No. 4 Health Law. 12 (1999)... 9 Physician's Desk Reference (54th ed. 2000)... 4 Marnie E. Rice & Grant T. Harris, The Treatment of Mentally Disordered Offenders 3 Psychol., Pub. Pol y & L. 126 (1997) Rafael A. Rivas-Vazquez et al., Atypical Antipsychotic Medications: Pharmacological Profiles and Psychological Implications, 31 Prof. Psychol.: Res. & Prac. 628 (2000)... passim Alex M. Siegel & Amiram Elwork, Treating Incompetence to Stand Trial, 14 L. and Human Behavior 57 (1990) , 23 David M. Siegel et al., Old Law Meets New Medicine: Revisiting Involuntary Psychotropic Medication of the Criminal Defendant, 2001 Wis. L. Rev J.K. Stanilla & G.M. Simpson, Treatment of Extrapyramidal Side Effects, in Textbook of Psychopharmacology 349 (Schatzberg & Nemeroff eds., 1998)... 7 J. Alexander Tanford, The Law and Psychology of Jury Instructions, 69 Neb. L. Rev. 71 (1990) v
6 A. Tuunainen et al., Newer Atypical Antipsychotic Medication Versus Clozapine for Schizophrenia, 2 Cochrane Database of Systematic Review pcd (2000)... 8 Robert M. Wettstein, Legal Aspects of Prescribing, in Drug-Induced Dysfunction in Psychiatry 145 (Matcheri S. Keshavan & John S. Kennedy eds., 1992)... 8 David B. Wexler & Bruce J. Winick, Therapeutic Jurisprudence and Criminal Justice Mental Health Issues, 16 Mental & Physical Disability L. Rep. 225 (1992) Bruce J. Winick, The Right to Refuse Mental Health Treatment (1997)... passim Bruce J. Winick, The MacArthur Treatment Competence Study: Legal and Therapeutic Implications, 2 Psych., Pub. Pol y and L. 137 (1996) Karen E. Whittemore & James R.P. Ogloff, Factors That Influence Jury Decision Making: Disposition Instructions and Mental States at the Time of the Trial, 19 L. & Hum. Behav. 243 (1995) vi
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