ALPHA GLUCOSIDASE INHIBITOR THERAPY

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1 ALPHA GLUCOSIDASE INHIBITOR THERAPY GLYSET Step 1: One generic formulary product containing one of the following ingredients: glimeperide, glipizide, metformin or pioglitazone. Step 2: Glyset PAGE 1 LAST UPDATED 11/2017

2 ANTIDEPRESSANT THERAPY EMSAM Step 1: Any two of the following: formulary, oral, generic, single-ingredient products bupropion, citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, mirtazapine, immediate release paroxetine, sertraline, immediate release venlafaxine, or extended release venlafaxine capsules. Step 2: Emsam PAGE 2 LAST UPDATED 11/2017

3 ATYPICAL ANTIPSYCHOTICS FANAPT, VRAYLAR 1.5 MG CAPSULE, VRAYLAR 3 MG CAPSULE, VRAYLAR 4.5 MG CAPSULE, VRAYLAR 6 MG CAPSULE Step 1: Two of the following oral, single-ingredient, generic atypical antipsychotics: olanzapine, quetiapine, risperidone, ziprasidone OR Seroquel XR. Step 2: Vraylar or Fanapt PAGE 3 LAST UPDATED 11/2017

4 FETZIMA THERAPY FETZIMA Step 1: Generic venlafaxine immediate release tablets or extended release capsules. Step 2: Fetzima PAGE 4 LAST UPDATED 11/2017

5 GLP1 AGONIST THERAPY BYDUREON, BYDUREON PEN, BYETTA, TRULICITY Step 1: Any one formulary generic product containing one of the following ingredients: glimeperide, glipizide, metformin, or pioglitazone. Step 2: Bydureon or Byetta or Trulicity PAGE 5 LAST UPDATED 11/2017

6 GLYXAMBI THERAPY GLYXAMBI Step 1: Any one formulary generic product containing one of the following ingredients: glimeperide, glipizide, metformin, or pioglitazone. Step 2: Glyxambi PAGE 6 LAST UPDATED 11/2017

7 INVEGA TRINZA THERAPY INVEGA TRINZA Step 1: Invega Sustenna Step 2: Invega Trinza PAGE 7 LAST UPDATED 11/2017

8 LAMA THERAPY TUDORZA PRESSAIR Step 1: Spiriva. Step 2: Tudorza Pressair. PAGE 8 LAST UPDATED 11/2017

9 LEUKOTRIENE MODIFIER ASTHMA THERAPY ZILEUTON ER, ZYFLO, ZYFLO CR Step 1: Trial of generic formulary montelukast or generic zafirlukast. Step 2: Zyflo, Zileuton ER, or Zyflo CR PAGE 9 LAST UPDATED 11/2017

10 NEUPRO THERAPY NEUPRO Step 1: Any one formulary product containing pramipexole or ropinirole. Step 2: Neupro PAGE 10 LAST UPDATED 11/2017

11 PENICILLAMINE THERAPY CUPRIMINE, SYPRINE Step 1: Depen Titra. Step 2: Cuprimine or Syprine PAGE 11 LAST UPDATED 11/2017

12 RYTARY RYTARY Step 1: Generic carbidopa/levodopa IR OR CR. Step 2: Rytary ER. PAGE 12 LAST UPDATED 11/2017

13 SGLT2 THERAPY INVOKAMET, INVOKAMET XR, INVOKANA, JARDIANCE, SYNJARDY Step 1: Any one formulary generic product containing one of the following ingredients: glimeperide, glipizide, metformin, or pioglitazone. Step 2: Invokana or Jardiance or Invokamet or Synjardy. For Jardiance or Synjardy only: ST does not apply for patients with cardiovascular (CV) disease, defined as one of the following: h/o MI, multi-vessel CAD, left main CAD, h/o stroke, Occlusive PAD, single-vessel CAD with documentation of unstable angina or a positive stress test for ischemia. PAGE 13 LAST UPDATED 11/2017

14 TOPICAL IMMUNOMODULATOR THERAPY ELIDEL Step 1: Any two formulary, generic topical corticosteroids. Step 2: Elidel PAGE 14 LAST UPDATED 11/2017

15 TRESIBA FLEXTOUCH THERAPY TRESIBA FLEXTOUCH U-100, TRESIBA FLEXTOUCH U-200 Step 1: Lantus Step 2: Tresiba Flextouch PAGE 15 LAST UPDATED 11/2017

16 UCERIS ORAL THERAPY UCERIS 9 MG ER TABLET Step 1: Both mesalamine 1200 mg delayed release and oral generic sulfasalazine. Step 2: Uceris Tablet PAGE 16 LAST UPDATED 11/2017

17 ULORIC THERAPY ULORIC Step 1: oral generic allopurinol. Step 2: Uloric PAGE 17 LAST UPDATED 11/2017

18 VYTORIN THERAPY EZETIMIBE-SIMVASTATIN, VYTORIN Step 1: Two generic formulary HMG-CoA reductase inhibitors (statin). Step 2: Vytorin or ezetimibe/simvastatin. PAGE 18 LAST UPDATED 11/2017

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