BIOLOGICAL PSYCHOLOGY II (2022 section 2) LECTURE SCHEDULE & GENERAL INFORMATION Fall 2003

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1 BIOLOGICAL PSYCHOLOGY II (2022 section 2) LECTURE SCHEDULE & GENERAL INFORMATION Fall 2003 LECTURE meets 2:00 3:15 Tu,Th, Ketchum 235 Final Exam: Monday Dec. 15, 4:30-7:00 p.m., Ketchum 235 Dr. Serge Campeau - Instructor Office: Muenzinger E-238; Phone (with voice mail): (checked weekdays): campeaus@psych.colorado.edu Office Hrs: TTh: 3:30-5:00, Fri 4:00-5:00; Additional times by appointment Course s Web page: Required Books: Kolb, B. & Whishaw, I.Q. (2001). An Introduction to Brain and Behavior, New York: Worth Publishers. Other Required Reading (Copy of excerpts on Reserve in Norlin Library): Excerpts from: Andreasen, N.C. (2001) Brave New Brain: Conquering mental illness in the era of the genome. New York: Oxford University Press. Joyce, J.N. and Hurtig, H.I. (1994) Neurodegenerative disorders, in Frazer, Molinoff and Winokur (Eds) Biological Bases of Brain Function and Disease. New York: Raven Press. Kolb, B. and Whishaw, I.Q. (2003) Fundamentals of Human Neuropsychology, 5th ed. New York: Worth Publishers. Kiernan, J.A. (1998). Barr s The Human Nervous System: an Anatomical Viewpoint. Philadelphia: Lippincott-Raven Publishers. Lickey, M.E. and Gordon, B. (1991) Medicine and Mental Illness. New York: W.H. Freeman & Co. Sacks, O. (1990) The Man Who Mistook His Wife for a Hat. New York: Harper Perennial Publications. COURSE OBJECTIVES: This course is a follow-up to the pre-requisite course Biological Psychology 1 (2012). In this course we will examine the biological properties of the brain in greater detail, with a focus on understanding the functional relationships between the brain and the mind (who we are what we think, feel, and do). An especially effective means of exploring this functional relationship is to examine a number of neurological and psychological disorders and to consider their symptoms as well as their biological causes, consequences and response to treatment. Therefore we will begin with an examination of neurological disorders - conditions in which we frequently know much about the actual locations and extent of brain damage. We will conclude with an examination of psychological disorders conditions in which we are just beginning to understand the biological changes within the brain that accompany these disorders. ADD/DROP POLICIES: The deadlines and policies for adding and dropping classes are clearly indicated in your Registration Handbook, and will be strictly adhered to. Until Sept. 10 at 5:00 pm, classes can be dropped without permission, with full tuition refunded. From Sept. 11 til Oct. 8 at 5:00 pm, course can be dropped WITH instructor s approval on an SAF form; you must be passing the course, and W remains on your record. It would be very very difficult (as a matter of fact, nearly impossible) to drop the class after Oct. 8 (requires Dean s petition and approval). PASS/FAIL option has to be declared on or before Sept. 12 at 5:00 pm. You can elect this option only if you are taking this class as an elective course.

2 Bio Psych 2022, Fall DISABILITY STATEMENT: If you have specific physical, psychiatric, or learning disabilities and require accommodations, please let me know early in the semester (first two weeks of classes) so that your learning needs may be appropriately met. You will need to provide documentation of your disability to the Disability Services Office in Willard 322 (phone ), and to myself. COURSE CALENDAR/OUTLINE Date Lecture Topic Reading Assignment Aug. 26 (Tu) Aug. 28 (Th) Sep. 2 (Tu) Unit 1: Cerebral Cortex and Brain Function Overview: brain behavior relationships, materialism vs. dualism Localization of function vs. brain equipotentiality; Cortical anatomy Cortical functional organization Kolb & Whishaw, pp ; Kiernan, pp Sep. 4 (Th) Cortical cellular organization Kiernan, pp Sep. 9 (Tu) Parietal lobe function Kolb & Whishaw (FHN), pp Sep. 11 (Th) Sep. 16 (Tu) Parietal lobe function Temporal lobe function Paper 1 Due Sacks, pp.8-22, 55-58,59-65, Kolb & Whishaw (FHN), pp Sacks, pp , Sep. 18 (Th) Frontal lobe function Kolb & Whishaw (FHN), pp Sep. 23 (Tu) Frontal lobe function Sep. 25 (Th) EXAM 1 - unit 1 Sacks, pp Unit 2: Subcortical Systems, Neurochemistry and Brain Function Sep. 30 (Tu) Subcortical anatomy Kolb & Whishaw, pp , Oct. 2 (Th) Oct. 7 (Tu) No Classes Fall Break Basic chemistry Oct. 9 (Th) Neurochemistry Kolb & Whishaw, pp Oct. 14 (Tu) Oct. 16 (Th) Oct. 21 (Tu) Principles of pharmacology Neurochemical disorders: Parkinson's disease Paper 2 Due Neurochemical disorders: Parkinson's disease Joyce & Hurtig, pp Sacks, pp , Oct. 23 (Th) Neurochemical disorders: Huntington's disease Joyce & Hurtig, pp

3 Bio Psych 2022, Fall Oct. 28 (Tu) Memory Disorders: hippocampal damage Kolb & Whishaw, pp Oct. 30 (Th) Memory disorders: Korsakoff's syndrome Kolb & Whishaw, pp Sacks, pp , Nov. 4 (Tu) EXAM 2 - unit 2 Unit 3: Brain Function and Psychological Disorders Nov. 6 (Th) Medical model of mental illness, diagnosis, DSM-IV Andreasen: Chap. 7 Nov. 11 (Tu) No Classes Instructor Away Nov. 13 (Th) Behavioral features and etiology of Schizophrenia Andreasen: pp Nov. 18 (Tu) Underlying biological mechanisms of Schizophrenia Andreasen: pp Nov. 20 (Th) Treatment of Schizophrenia Andreasen: pp Nov. 25 (Tu) Nov. 27 (Th) Dec. 2 (Tu) Behavioral features and etiology of unipolar and bipolar depression Thanksgiving Holiday No Classes Underlying biological mechanisms of unipolar and bipolar depression Paper 3 Due Andreasen: pp Andreasen: pp Dec. 4 (Th) Treatment of unipolar depression Andreasen: pp Dec. 9 (Tu) Treatment of bipolar depression Lickey & Gordon: Chap. 14 Dec. 11 (Th) Behavioral features, etiology and underlying mechanisms and treatment of anxiety disorders Dec 15 (Mo) FINAL EXAM - unit 3 Andreasen: pp COURSE GRADING Seventy-five percent of your final grade will be based on the scores you obtain on the 3 unit exams (25% each). Twenty-five percent of your final grade will be based on 3 papers (see below). In those extreme emergencies when an exam has to be missed a substitute essay exam can be arranged to be taken in its place. There will be a total of 400 points possible for this course: Exam points Exam points Exam points 3 Papers 100 points Total: 400 points Each examination will consist of a combination of short answers, true-falses, matching and multiple choice questions. The examination questions will draw upon all of the material covered in class as well as in the reading assignments; however, the primary focus of the exams will be on material covered in class.

4 Bio Psych 2022, Fall ***ATTENDANCE COUNTS: I will take attendance each class period. If you miss 3 or fewer class periods for the entire semester then I will give you 15 extra-credit points. Note: excused absences will still count as absences, but may help out in the case of a borderline grade. The final letter grade will be assigned according to the following final percentages, with one exception. You must score over 60% on at least 1 exam to pass the course: Letter Grade Point Total Percentage A % A % B % B % B % C % C % C % D % D % F < 240 < 60% Instructions for the 3 Written Reports Due on Sep. 16, Oct. 16, and Dec. 2 Each written report is to be a brief discussion of a "controversial" issue that is relevant to a topic covered in this course. Each report should be based on at least 4 sources. One of these sources may be from the general media (e.g. magazines, newspaper, TV, world-wide web). The remaining sources must be from a scientific book or scientific journal. Each report should be of 3-5 double spaced typed pages in length. Each report should contain the following information: 1) Description of the issue (controversy) 2) How is the issue relevant to this course (remember the main focus of the course is the study of the relationship between the brain and behavior)? 3) Description of the biopsychology related details (e.g. mechanisms of action for particular drugs, brain areas of interest, etc.) 4) What is your position on the issue? 5) How has the information that you gathered from your sources influenced your position on the issue? 6) Your sources of information (include a bibliography page this page doesn't count towards the 3-5 page limit). Bibliography and Citations: Your bibliography page (reference list) should include all of the articles/books that you have read and refer to within your paper. Within the text, cite only articles/books that you have read (or at least skimmed). So, every article/book in your bibliography should be cited somewhere in the text, and conversely, every cited article/book in your text should also appear in your bibliography.

5 Bio Psych 2022, Fall Finally, don't use quotations. Nothing that a scientist writes is so eloquent that it deserves to be directly quoted (don't quote me on this). You should always be able to adequately paraphrase what someone else writes. Also be careful to not plagiarize when paraphrasing; changing a few words here and there is still plagiarizing. If a report represents a sincere effort and includes all of the above 6 pieces of information then it will be given at least 80 points. I will devote 5 points toward the "mechanical" quality of the paper, i.e. use of good grammar and absence of typographical errors, formatting problems. The remaining 15 points will be awarded to reports which "stand head and shoulders" above the other reports. Please do original work. If I receive reports that are clearly copied from each other, then those reports will be given no credit and the appropriate University Code of Conduct will be adhered to in dealing with the student(s) involved. Examples of some topics that you may choose to write reports on: Should fetal tissue be used for brain transplants in patients with Parkinson's disease or other diseases? Is there evidence for a biological basis to sociopathic behavior, and if so, how should those individuals be dealt with? Do anabolic steroids directly affect a person's behavior and personality, and if so, should they be banned? Is there evidence that over exposure to aluminum can cause Alzheimer's disease, and if so, should aluminum cook ware be banned? Should electroconvulsive therapy (ECT) still be used to treat depression? Is Prozac being over prescribed or misprescribed? Should any physician be allowed to prescribe antidepressants or only psychiatrists? Should genetic screening be used to determine whether a fetus should be aborted or to be used in helping a couple determine whether they should even attempt to have an offspring? Is the medical model appropriate for dealing with mental illness? Is psychotherapy effective in treating psychological disorders? Are anxiety disorders and depression different manifestations of the same underlying disorder? Should Ritalin be given to hyperactive children? Is Tourette's syndrome a neurological disorder or a psychological disorder? Can memory be improved by certain drugs? Is sexual orientation primarily innate or socially determined? Should animals be used for basic research? Is there a biological basis for hypnosis? Is St. John's Wort an effective treatment for depression? Is there a genetic contribution to drug addiction?

6 Bio Psych 2022, Fall A FINAL WORD I hope that you find this course to be fun, stimulating, insightful, and challenging. I look forward to working with you throughout this semester and feedback will be taken very seriously. I would like to thank Dr. Robert Spencer for providing the blueprint of this syllabus.