Cytology and Surgical Pathology of Gynecologic Neoplasms
|
|
- Angela McKenzie
- 5 years ago
- Views:
Transcription
1 Cytology and Surgical Pathology of Gynecologic Neoplasms
2 Current Clinical Pathology ANTONIO GIORDANO, MD, PHD SERIES EDITOR For further titles published in this series, go to
3 Cytology and Surgical Pathology of Gynecologic Neoplasms Edited by David Chhieng, MD, MBA, MSHI Yale University School of Medicine, New Haven, CT, USA Pei Hui, MD, PhD Yale University School of Medicine, New Haven, CT, USA
4 Editors David Chhieng Department of Pathology Yale University School of Medicine New Haven, CT USA Pei Hui Department of Pathology Yale University School of Medicine New Haven, CT USA ISBN e-isbn DOI / Springer New York Dordrecht Heidelberg London Library of Congress Control Number: Springer Science+Business Media, LLC 2011 All rights reserved. This work may not be translated or copied in whole or in part without the written permission of the publisher (Springer Science+Business Media, LLC, 233 Spring Street, New York, NY 10013, USA), except for brief excerpts in connection with reviews or scholarly analysis. Use in connection with any form of information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed is forbidden. The use in this publication of trade names, trademarks, service marks, and similar terms, even if they are not identified as such, is not to be taken as an expression of opinion as to whether or not they are subject to proprietary rights. If there is cover art, insert cover illustration line. Give the name of the cover designer if requested by publishing. While the advice and information in this book are believed to be true and accurate at the date of going to press, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (
5 Preface The neoplasms found in the female genital tract are numerous and diagnostically growing more complex. Understanding gynecological pathology can be overwhelming. As an extension to comprehensive textbooks that are ubiquitous around sign-out microscope, this text has been written to provide a practical reference for practicing pathologists and cytopathologists in a quick and concise fashion. The primary focus of our book is on gynecological tumors, specifically common ones and their benign mimics, and every effort is made to integrate major diagnostic criteria with the ancillary studies. We hope we have made concrete the usually abstract dictum of gynecological pathology on both histological and cytological grounds. Understandably, as one of the highly complex pathology specialties, it is impossible to include every aspect of its ingredients in this compact reference book. Hematoxylin and eosin staining and immunohistochemistry remain the cornerstones of diagnostic gynecological pathology. This manual presents a logical approach to pathological diagnosis based primarily on conventional histology and cytology and assembles the most important diagnostic features of common neoplastic entities of the female genital tract. The most common differential diagnosis is discussed when necessary. Many entities in gynecological pathology may have multiple names and variants, but an attempt has been made to present a concise approach to the diagnostic problem often reflecting opinions of the authors. Throughout the book, the approach is simple and straightforward entity-based discussion of each diagnostic entity followed by cytopathology related to the whole group of disease under each chapter. Because of this practical approach and the concrete and accessible nature of the material, we believe that this text also forms the basis for a bridge course to introduce residents, fellows, and junior practitioners to the specialty practice of gynecological pathology. We wish to express our deepest gratitude to all of our mentors, past and current, who have been the major source of knowledge and courage in our academic careers. Our sincere appreciation goes to many colleagues and trainees in pathology at Yale University and University at Alabama, who have shared or presented many cases that provided the basis for this volume. v
6
7 Contents 1 Normal Histology of Female Genital Organs Normal Histology of Vulva Normal Histology of Vagina Normal Histology of Cervix Normal Histology of Uterus Normal Histology of Fallopian Tube Normal Histology of Ovary Normal Cytology of Female Genital Tract Organs Squamous Cells Parabasal Squamous Cells Endocervical Cells Squamous Metaplastic Cells Endometrial Cells Direct Sampling of the Lower Uterine Segment The Bethesda System Specimens Adequacy Minimum Squamous Cellularity Criteria Endocervical/Transformation Zone Component Obscuring Factors Management of Women with Unsatisfactory Pap Test... Suggested Reading Lesions of the Vulva and Vagina General Classification of Tumors or Tumor-Like Conditions of Vulva and Vagina Benign, Preneoplastic, and In Situ Neoplastic Squamous Lesions Glandular Lesions Benign Glandular Lesions Adenocarcinomas Other Epithelial or Epithelioid Lesions Melanocytic Lesions Mesenchymal and Lymphoid Neoplasms Secondary Tumors Cytology of Vulva Dysplasia (Vulvar Intraepithelial Neoplasia) Squamous Cell Carcinoma vii
8 viii Contents Paget s Disease Mimics of Neoplastic Diseases Cytology of Vagina Diethylstilbestrol-Related Abnormalities Vaginal Intraepithelial Neoplasia Squamous Cell Carcinoma Embryonal Rhabdomyosarcoma Mimics of Neoplastic Diseases Role of Vaginal Cytology Screening After Total Hysterectomy... Suggested Reading Squamous Lesions of the Cervix General Classification of Tumors of Cervix Squamous Intraepithelial Lesions and Other HPV-Related Lesions Squamous Cell Carcinomas Cytology Atypical Squamous Cells ASC-US ASC-H Low-Grade Squamous Intraepithelial Lesion High-Grade Squamous Intraepithelial Lesions LSIL Cannot Rule Out HSIL HSIL with Glandular Involvement Squamous Cell Carcinoma Mimics of Neoplastic Diseases Clinical Staging and Management... Suggested Reading Glandular Lesions of the Cervix Cervical Polyp and Other Tumor-Like Conditions Glandular Dysplasia/Adenocarcinoma In Situ Invasive Adenocarcinomas Cytology of Cervical Glandular Lesions Atypical Glandular Cells, Endocervical Origin Endocervical Adenocarcinoma In Situ Endocervical Adenocarcinoma Mimics of Neoplastic Diseases Other Primary Malignant Neoplasms... Suggested Reading Human Papillomavirus for Cervical Pathology Classification, Properties, and Viral Genome Natural History of HPV Infection Distribution of HPV in Cervical Lesions Methods of Detection Indications for HPV Testing Applications for HPV Testing in Cytology Triage of ASC-US and/or LSIL
9 Contents Surveillance After Treatment of CIN Primary Screening HPV Genotyping... Suggested Reading... ix Endometrial Epithelial Neoplasms General Classification of Uterine Corpus Neoplasms Benign Tumors and Tumor-Like Conditions Endometrial Hyperplasia Endometrial Carcinomas Cytology Atypical Glandular Cells, Endometrial Origin Endometrial Adenocarcinoma Gynecologic Cytology and the Detection of Endometrial Hyperplasia and Malignancy Hyperchromatic Crowded Groups Suggested Reading Nonepithelial Tumors of Uterine Corpus General Classification of Nonepithelial Tumors of Uterine Corpus Endometrial Stromal Tumors Mullerian Mixed Epithelial and Stromal Tumors Smooth Muscle Tumors Other Mesenchymal Tumors Cytology Sarcomas Melanoma Lymphoma Metastatic Tumors Suggested Reading Gestational Trophoblastic Disease General Classification of Gestational Trophoblastic Disease Hydatidiform Moles Complete Hydatidiform Mole Partial Hydatidiform Mole Invasive Hydatidiform Mole Gestational Choriocarcinoma Placental Site Trophoblastic Tumor Epithelioid Trophoblastic Tumor Exaggerated Placental Site Reaction Placental Site Nodule Suggested Reading Tumors of Fallopian Tube and Broad Ligament Benign Tumors and Tumor-Like Conditions Malignant Epithelial Tumors Cytology Suggested Reading
10 x Contents 10 Epithelial Neoplasms of Ovary General Classification of Ovarian Neoplasms Primary Epithelial Ovarian Neoplasms Ovarian Epithelial Tumors of Uncertain Origin Secondary Carcinomas Involving Ovary Cytology Exfoliative Cytology in Pap Test Fine Needle Aspiration Biopsy Nonneoplastic Cysts Suggested Reading Nonepithelial Tumor of Ovary General Classification of Nonepithelial Ovarian Tumors Ovarian Germ Cell Tumors Ovarian Sex Cord-Stromal Tumors Granulosa Cell Tumors Thecomas and Fibrous Tumors Sertoli-Stromal Cell Tumors Steroid Cell Tumors Miscellaneous Primary Ovarian Tumors Cytology Mature Cystic Teratomas Dysgerminoma Other Germ Cell Tumors Granulosa Cell Tumors Suggested Reading Tumors of Peritoneum General Classification of Tumors of Peritoneum Mesotheliomas Other Mesenchymal Tumors Cytology Cytology of Benign and Nonneoplastic Conditions Psammoma Bodies Neoplastic Conditions Ancillary Studies Suggested Reading Appendix Index
Frozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA
Frozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA For further volumes, go to http://www.springer.com/series/7869 Frozen Section Library: Central Nervous System Richard A. Prayson
More informationAMERICAN JOINT COMMITTEE ON CANCER AJCC CANCER STAGING
AMERICAN JOINT COMMITTEE ON CANCER AJCC CANCER STAGING ATLAS EDITORS FREDERICK L. GREENE, m.d. Chair, Department of General Surgery Carolinas Medical Center Charlotte, North Carolina CAROLYN C. COMPTON,
More informationFrozen Section Library: Pleura
Frozen Section Library: Pleura For other titles published in this series, go to www.springer.com/series/7869 Frozen Section Library: Pleura Philip T. Cagle, MD Weill Medical College of Cornell University,
More informationGynaecological Malignancies
Gynaecological Malignancies Dr Rodney Itaki Lecturer Anatomical Pathology Discipline University of Papua New Guinea Division of Pathology School of Medicine & Health Sciences Overview Genital tract tumors
More informationEssentials in Cytopathology Series
Essentials in Cytopathology Series ESSENTIALS IN CYTOPATHOLOGY SERIES Dorothy L. Rosenthal, MD, FIAC, Series Editor 1. D.P. Clark and W.C. Faquin: Thyroid Cytopathology. 2005 ISBN 0-387-23304-0 Douglas
More informationPreface to the Second Edition
Preface to the Second Edition This second edition of Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach follows a number of favorable comments we received about the first edition. As
More informationECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION
ECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION ECG INTERPRETATION: FROM PATHOPHYSIOLOGY TO CLINICAL APPLICATION by Fred Kusumoto, MD Electrophysiology and Pacing Service Division of Cardiovascular
More informationAtlas of Lymph Node Anatomy
Atlas of Lymph Node Anatomy Mukesh G. Harisinghani Editor Atlas of Lymph Node Anatomy This publication was developed through an unrestricted educational grant from Siemens. Editor Mukesh G. Harisinghani
More informationFrozen Section Library: Lung
Frozen Section Library: Lung FROZEN SECTION LIBRARY SERIES Philip T. Cagle, MD, Series Editor 1. Timothy Craig Allen, Philip T. Cagle: Frozen Section Library: Lung 2009 ISBN 978-0-387-09572-1 Frozen Section
More informationEU guidelines for reporting gynaecological cytology
EU guidelines for reporting gynaecological cytology Amanda Herbert Guy s & St Thomas Foundation NHS Trust 5th EFCS Annual Tutorial, Trondheim, Norway 28 th May 1 st June 2012 EU guidelines aim to harmonize
More informationChronic Pain. For other titles published in this series, go to
Chronic Pain For other titles published in this series, go to www.springer.com/series/7633 Dawn A. Marcus, M.D. Chronic Pain A Primary Care Guide to Practical Management Second Edition Dawn A. Marcus,
More informationCancer Treatment and Research
Cancer Treatment and Research Volume 155 Series Editor Steven T. Rosen For further volumes: http://www.springer.com/series/5808 Boris Pasche Editor Cancer Genetics 123 Editor Boris Pasche, MD, PhD, FACP
More informationMaking Sense of Cervical Cancer Screening
Making Sense of Cervical Cancer Screening New Guidelines published November 2012 Tammie Koehler DO, FACOG The incidence of cervical cancer in the US has decreased more than 50% in the past 30 years because
More informationUnderstanding Your Pap Test Results
Understanding Your Pap Test Results Most laboratories in the United States use a standard set of terms called the Bethesda System to report pap test results. Normal: Pap samples that have no cell abnormalities
More informationMaurie Markman, MD, Series Editor
Palliative Care Current Clinical Oncology Maurie Markman, MD, Series Editor For other titles published in this series, go to www.springer.com/series/7631 Palliative Care A Ca s e-b a s e d Gu i d e Edited
More informationSpringerBriefs in Child Development
SpringerBriefs in Child Development For further volumes: http://www.springer.com/series/10210 Daniel F. Shreeve Reactive Attachment Disorder A Case-Based Approach Daniel F. Shreeve The Carilion Clinic
More informationChapter 10: Pap Test Results
Chapter 10: Pap Test Results On completion of this section, the learner will be able to: 1. Identify how Pap test results are interpreted and the reasons for normal and abnormal results. 2. Describe the
More informationGynecologic Oncology
Gynecologic Oncology Ramez N. Eskander Robert E. Bristow Editors Gynecologic Oncology A Pocketbook Editors Ramez N. Eskander, M.D. Assistant Professor Division of Gynecologic Oncology Department of Obstetrics
More informationCervical Cancer Screening for the Primary Care Physician for Average Risk Individuals Clinical Practice Guidelines. June 2013
Cervical Cancer Screening for the Primary Care Physician for Average Risk Individuals Clinical Practice Guidelines General Principles: Since its introduction in 1943, Papanicolaou (Pap) smear is widely
More informationIndex. Cytoplasm, nonepithelial malignant tumor features 70
Accurette device 23 Adenosarcoma, differential diagnosis 80, 81 Arias-Stella reaction 65 Atypical endocervical cells 8 Atypical endometrial cells 8 Atypical glandular cells (AGC) 8, 9 Atypical glandular
More informationSPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. Gerhard Bauer Joseph S. Anderson. Gene Therapy for HIV From Inception to a Possible Cure
SPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY Gerhard Bauer Joseph S. Anderson Gene Therapy for HIV From Inception to a Possible Cure 123 SpringerBriefs in Biochemistry and Molecular Biology For
More informationRadiation Therapy for Skin Cancer
Radiation Therapy for Skin Cancer Armand B. Cognetta Jr. William M. Mendenhall Editors Radiation Therapy for Skin Cancer Editors Armand B. Cognetta Jr. Dermatology Associates of Tallahassee Chief, Division
More informationRadiology Illustrated
Radiology Illustrated For further volumes: http://www.springer.com/series/11755 In-One Kim Editor Radiology Illustrated: Pediatric Radiology Editor In-One Kim, M.D. Department of Radiology Seoul National
More informationWorkshop for O& G trainees and paramedics 17 Dec 2011 Cytological Interpretation
Workshop for O& G trainees and paramedics 17 Dec 2011 Cytological Interpretation May Yu Director of Cytology Laboratory Service Department of Anatomical & Cellular Pathology Prince of Wales Hospital Cervical
More informationBC Cancer Cervix Screening 2015 Program Results. February 2018
BC Cancer Cervix Screening 2015 Program Results BC Cancer Cervix Screening 2015 Program Results 2 Table of Contents BC Cancer Cervix Screening 2015 Program Results... 1 Table of Contents... 2 Program Overview...
More informationIn Clinical Practice
In Clinical Practice Taking a practical approach to clinical medicine, this series of smaller reference books is designed for the trainee physician, primary care physician, nurse practitioner and other
More informationDifferential Diagnosis of Movement Disorders in Clinical Practice
Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Peter Hedera Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Parkinson's Clinic
More informationAlexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov. Breast Ultrasound
Breast Ultrasound Alexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov Breast Ultrasound Alexander N. Sencha Department of Ultrasound Diagnostics Yaroslavl Railway Clinic Yaroslavl
More informationCongenital Hip Disease in Adults
Congenital Hip Disease in Adults George Hartofilakidis George C. Babis Kalliopi Lampropoulou-Adamidou Congenital Hip Disease in Adults George Hartofilakidis, MD, FACS Orthopaedic Department Medical School
More informationThe Pharmacology of Alcohol and Drugs of Abuse and Addiction
The Pharmacology of Alcohol and Drugs of Abuse and Addiction Norman S. Miller The Pharmacology of Alcohol and Drugs of Abuse and Addiction Springer-Verlag New York Berlin Heidelberg London Paris Tokyo
More informationPATHOLOGY OF THE FEMALE GENITAL TRACT
MBBS 2 nd Yr. Lecture Dr. Annie Cheung September 30, 2002 9:30 am LT2,G/F, Academic and Administration Block Faculty of Medicine Building UROGENITAL SYSTEM PATHOLOGY OF THE FEMALE GENITAL TRACT Learning
More informationColposcopy. Attila L Major, MD, PhD
Colposcopy Attila L Major, MD, PhD Histology Colposcopy Cytology It has been estimated that annual Pap smear testing reduces a woman s chance of dying of cervical cancer from 4 in 1000 to about 5 in 10,000
More informationSpringerBriefs in Cancer Research
SpringerBriefs in Cancer Research For further volumes: http://www.springer.com/series/10786 Natalia Aptsiauri Angel Miguel Garcia-Lora Teresa Cabrera MHC Class I Antigens In Malignant Cells Immune Escape
More informationClinical Practice Guidelines June 2013
Clinical Practice Guidelines June 2013 General Principles: The Papanicolaou (Pap) smear is widely credited with reducing mortality from cervical cancer, and remains the single best method for the early
More informationDating Neurological Injury
Dating Neurological Injury wwwwwwwww Jeff L. Creasy Dating Neurological Injury A Forensic Guide for Radiologists, Other Expert Medical Witnesses, and Attorneys Jeff L. Creasy Associate Professor of Neuroradiology
More informationCervical Screening for Dysplasia and Cancer in Patients with HIV
Cervical Screening for Dysplasia and Cancer in Patients with HIV Adult Clinical Guideline from the New York State Department of Health AIDS Institute w w w.hivg uidelines.org Purpose of the Guideline Increase
More informationBCCCP Approved ICD-9 Code List Fiscal Year 2010
BCCCP Approved ICD-9 List Fiscal Year 2010 Diagnosis Description 174.0 Malignant neoplasm of female breast; Nipple and areola 174.1 Malignant neoplasm of female breast; Central portion 174.2 Malignant
More informationHyperchromatic Crowded Groups: What is Your Diagnosis? Session 3000
Hyperchromatic Crowded Groups: What is Your Diagnosis? Session 3000 Thomas A. Bonfiglio, M.D. Professor Emeritus, Pathology and Laboratory Medicine University of Rochester Disclosures In the past 12 months,
More informationFaculty Pap Smear Guidelines: Family Planning Update 2008 Part Two
Faculty Pap Smear Guidelines: Family Planning Update 2008 Part Two Seshu P. Sarma, MD, FAAP Emory University Regional Training Center Atlanta, Georgia Produced by the Alabama Department of Public Health
More informationProgress in Social Psychiatry in Japan
Progress in Social Psychiatry in Japan Yoshibumi Nakane Progress in Social Psychiatry in Japan An Approach to Psychiatric Epidemiology Yoshibumi Nakane Department of Neuropsychiatry Nagasaki University
More informationPathology of the female genital tract
Pathology of the female genital tract Common illnesses of the female genital tract Before menarche Developmental anomalies Tumors (ovarial teratoma) Amenorrhea Fertile years PCOS, ovarian cysts Endometriosis
More informationAppropriate Use of Cytology and HPV Testing in the New Cervical Cancer Screening Guidelines
Appropriate Use of Cytology and HPV Testing in the New Cervical Cancer Screening Guidelines Tim Kremer, MD Ralph Anderson, MD 1 Objectives Describe the natural history of HPV particularly as it relates
More informationHandbook of Pediatric Eye and Systemic Disease
Handbook of Pediatric Eye and Systemic Disease Handbook of Pediatric Eye and Systemic Disease Edited by Kenneth W. Wright, MD Director, Wright Foundation for Pediatric Ophthalmology Director, Pediatric
More informationHODGKIN S AND NON-HODGKIN S LYMPHOMA
HODGKIN S AND NON-HODGKIN S LYMPHOMA edited by JOHN P. LEONARD, MD Center for Lymphoma and Myeloma Weill Medical College of Cornell University New York Presbyterian Hospital New York, NY MORTON COLEMAN,
More informationThe ABCs of TBS. A Novice's Guide to the Bethesda System
CE U P D A T E W O M E N ' S HEALTH III Julia Woodruff Wildes, MD The ABCs of TBS A Novice's Guide to the Bethesda System This is the third and final article in a three-part series on women's health. The
More informationEndometrial polyp icd-10
Endometrial polyp icd-10 Maternity Dx (12-55 years) Female Dx. Applicable To. Placental polyp. O90.89. ) Codes. N84 Polyp of female genital tract. N84.0 Polyp of corpus uteri; N84.1 Polyp of cervix uteri;
More information2/9/2015. Bartholin Cyst. Vulva: Squamous epithelium skin. Vagina: Squamous epithelium mucosa. Cervix: Ectocervix: squamous Endocervix: glandular
Vulva: Squamous epithelium skin Bartholin Cyst Vagina: Squamous epithelium mucosa Cervix: Ectocervix: squamous Endocervix: glandular Slide courtesy of Dr. Lodge Rigal Slide courtesy of Dr. Lodge Rigal
More informationThe society for lower genital tract disorders since 1964.
The society for lower genital tract disorders since 1964. Updated Consensus Guidelines for Managing Abnormal Cervical Cancer Screening Tests and Cancer Precursors American Society for and Cervical Pathology
More informationDeath Threats and Violence
Death Threats and Violence Stephen J. Morewitz Death Threats and Violence New Research and Clinical Perspectives Stephen J. Morewitz San Francisco, California Tarzana, California Buffalo Grove, Illinois
More informationManagement of Headache and Headache Medications
Management of Headache and Headache Medications Lawrence D. Robbins, M.D. Management of Headache and Headache Medications Foreword by Jerome Goldstein, M.D. Springer-Verlag New York Berlin Heidelberg London
More information!"#$%&'(#)*$+&,$-&.#,$/#0()1-$ ),1')$2(%&,2#,%$%(0'#$34567$
!"#$%&'(#)*$+&,$-&.#,$/#0()1-$ ),1')$2(%&,2#,%$%(0'#$34567$ Updated Consensus Guidelines for Managing Abnormal Cervical Cancer Screening Tests and Cancer Precursors American Society for and Cervical Pathology
More informationNational Cervical Screening Program MBS Item Descriptors
National Cervical Screening Program MBS Item Descriptors Item Item descriptor 73070 A test, including partial genotyping, for oncogenic human papillomavirus that may be associated with cervical pre-cancer
More informationCellular Pathology Of Glandular Lesions And Uncommon Neoplasms Of The Cervix By Glenn McCluggage;John Tidy;John Smith READ ONLINE
Cellular Pathology Of Glandular Lesions And Uncommon Neoplasms Of The Cervix By Glenn McCluggage;John Tidy;John Smith READ ONLINE If looking for a book by Glenn McCluggage;John Tidy;John Smith Cellular
More informationPATHOLOGY OF MALIGNANT MELANOMA
PATHOLOGY OF MALIGNANT MELANOMA Springer Science+Business Media, LLC PATHOLOGY of MALIGNANT MELANOMA Raymond L. Barnhill, MD Professor of Dermatology and Pathology, Departments of Dermatology and Pathology,
More informationSpringer Healthcare. Understanding and Diagnosing Ovarian Cancer. Concise Reference: Krishnansu S Tewari, Bradley J Monk
Concise Reference: Understanding and Diagnosing Ovarian Cancer Krishnansu S Tewari, Bradley J Monk Extracted from: The 21 st Century Handbook of Clinical Ovarian Cancer Published by Springer Healthcare
More informationCervical Cancer : Pap smear
Taking a PAP SMEAR Cervical Cancer : Pap smear George N Papanicolaou introduced cervical cytology in clinical practice in 1940 In 1945, PAP smear was endorsed by American cancer society as an effective
More informationGlandular lesions in cervical cytology. Margareta Strojan Fležar Institute of Pathology Faculty of Medicine University of Ljubljana Slovenia
Glandular lesions in cervical cytology Margareta Strojan Fležar Institute of Pathology Faculty of Medicine University of Ljubljana Slovenia 2nd PANNONIA CONGRESS OF PATHOLOGY, SIÓFOK, HUNGARY, 17-19 MAY
More informationVulva Inflammatory Disorders Lichen Planus Fixed Drug Eruption Erythema Multiforme Plasmacytosis Mucosae (Zoon) Lichen Sclerosus Allergic Contact
Vulva Inflammatory Disorders Lichen Planus Fixed Drug Eruption Erythema Multiforme Plasmacytosis Mucosae (Zoon) Lichen Sclerosus Allergic Contact Dermatitis Psoriasis Lichen Simplex Chronicus Foreign Body
More informationClinical Guidance: Recommended Best Practices for Delivery of Colposcopy Services in Ontario Best Practice Pathway Summary
Clinical Guidance: Recommended Best Practices for Delivery of Colposcopy Services in Ontario Best Practice Pathway Summary Glossary of Terms Colposcopy is the examination of the cervix, vagina and, in
More informationStandards for Pathology Informatics in Australia (SPIA)
Standards for Pathology Informatics in Australia (SPIA) Reporting Terminology and Codes Cytopathology (v3.0) Superseding and incorporating the Australian Pathology Units and Terminology Standards and Guidelines
More informationRespiratory Medicine Series Editor: Sharon I.S. Rounds. Marc A. Judson Editor. Pulmonary Sarcoidosis A Guide for the Practicing Clinician
Respiratory Medicine Series Editor: Sharon I.S. Rounds Marc A. Judson Editor Pulmonary Sarcoidosis A Guide for the Practicing Clinician Respiratory Medicine Series Editor: Sharon I.S. Rounds For further
More informationInstitute of Pathology First Faculty of Medicine Charles University. Ovary
Ovary Barrett esophagus ph in vagina between 3.8 and 4.5 ph of stomach varies from 1-2 (hydrochloric acid) up to 4-5 BE probably results from upward migration of columnar cells from gastroesophageal junction
More informationHistological Typing Of Cancer And Precancer Of The Oral Mucosa
Histological Typing Of Cancer And Precancer Of The Oral Mucosa 1 / 7 2 / 7 3 / 7 Histological Typing Of Cancer And Within the last decade, histologic grading has become widely accepted as a powerful indicator
More informationUrinary Tract Infection
Urinary Tract Infection Abhay Rané Ranan Dasgupta Editors Urinary Tract Infection Clinical Perspectives on Urinary Tract Infection Editors Abhay Rané, MS, FRCS, FRCS (Urol) Department of Urology Surrey
More informationUltrasound Mammography
Ultrasound Mammography B.-J. Hacke16er V. Duda G. Lauth Ultrasound Mammography Methods, Results, Diagnostic Strategies With the Collaboration of Jack Jellins Foreword by Elizabeth Kelly-Fry With 186 Illustrations
More informationSami Shousha Editor. Breast Pathology. Problematic Issues
Breast Pathology Editor Breast Pathology Problematic Issues Editor Charing Cross Hospital Imperial College Healthcare NHS Trust & Imperial College London United Kingdom ISBN 978-3-319-28653-2 ISBN 978-3-319-28655-6
More informationACGME Competency / Milestone Assessment. The Pap Test. Ricardo R. Lastra, MD Zubair W. Baloch, MD, PhD
1 ACGME Competency / Milestone Assessment The Pap Test Ricardo R. Lastra, MD Zubair W. Baloch, MD, PhD Department of Pathology & Laboratory Medicine University of Pennsylvania, Perelman School of Medicine
More informationEndometrial adenocarcinoma icd 10 code
P ford residence southampton, ny Endometrial adenocarcinoma icd 10 code Jun 24, 2014. Billable Medical Code for Malignant Neoplasm of Corpus Uteri, Except Isthmus Diagnosis Code for Reimbursement Claim:
More informationDiagnosis of Endometrial Biopsies and Curettings
Diagnosis of Endometrial Biopsies and Curettings Michael T. Mazur RobertJ. Kurman Diagnosis of Endometrial Biopsies and Curettings A Practical Approach With 209 Illustrations t Springer Science+Business
More informationFemale Reproduc.ve System. Kris.ne Kra7s, M.D.
Female Reproduc.ve System Kris.ne Kra7s, M.D. Female Reproduc.ve System Outline Cervix Uterus Ovaries Breast Female Reproduc.ve System Outline Cervix Cervical carcinoma Cervical Carcinoma Once the most
More informationDysplasia: layer of the cervical CIN. Intraepithelial Neoplasia. p16 immunostaining. 1, Cervical. Higher-risk, requires CIN.
CLINICAL PRACTICE GUIDELINE Guideline Number: DHMP_DHMC_PG1015 Guideline Subject: Routine Cervical Cancer Screening Effective Date: 9/2018 Revision Date: 9/2019 Pages: 2 of 2 Quality Management Committee
More informationCase year female. Routine Pap smear
Case 1 57 year female Routine Pap smear Diagnosis? 1. Atypical glandular cells of unknown significance (AGUS) 2. Endocervical AIS 3. Endocervical adenocarcinoma 4. Endometrial adenocarcinoma 5. Adenocarcinoma
More informationCervical Cancer Screening. David Quinlan December 2013
Cervical Cancer Screening David Quinlan December 2013 Cervix Cervical Cancer Screening Modest variation provincially WHO and UK begin at 25 stop at 60 Finland begin at 30 stop at 60 Rationale for
More informationPRE TEST CERVICAL SCREENING MANAGEMENT COLPOSCOPY PATHOLOGIC DIAGNOSIS AND TREATMENT
PRE TEST CERVICAL SCREENING MANAGEMENT COLPOSCOPY PATHOLOGIC DIAGNOSIS AND TREATMENT QUESTION #1 WHICH OF THE FOLLOWING IS NOT A RISK FACTOR FOR CERVICAL CANCER? A. HIGH RISK HPV B. CIGARETTE SMOKING C.
More informationIdentifying, Assessing, and Treating Conduct Disorder at School
Identifying, Assessing, and Treating Conduct Disorder at School Developmental Psychopathology at School Series Editors: Shane R. Jimerson, University of California, Santa Barbara, CA, USA Stephen E. Brock,
More informationPap Smears Pelvic Examinations Well Woman Examinations. When should you have them performed???
Pap Smears Pelvic Examinations Well Woman Examinations. When should you have them performed??? Arlene Evans-DeBeverly, PA-C Copyright 2012 There are always ongoing changes in gynecology, including the
More informationEradicating Mortality from Cervical Cancer
Eradicating Mortality from Cervical Cancer Michelle Berlin, MD, MPH Vice Chair, Obstetrics & Gynecology Associate Director, Center for Women s Health June 2, 2009 Overview Prevention Human Papilloma Virus
More informationCervical Testing and Results Management. An Evidenced-Based Approach April 22nd, Debora Bear, MSN, MPH
Cervical Testing and Results Management An Evidenced-Based Approach April 22nd, 2010 Debora Bear, MSN, MPH Assistant Medical Director for Planned Parenthood of New Mexico, Inc. Burden of cervical cancer
More informationEndometrial Cytology with Tissue Correlations
Endometrial Cytology with Tissue Correlations ESSENTIALS IN CYTOPATHOLOGY SERIES Dorothy L. Rosenthal, MD, FIAC, Series Editor Editorial Board Syed Z. Ali, MD Douglas P. Clark, MD Yener S. Erozan, MD 1.
More informationchapter 4. The effect of oncogenic HPV on transformation zone epithelium
chapter 4. The effect of oncogenic HPV on transformation zone epithelium CHAPTER 1 All squamous cervical cancer (and probably all cervical adenocarcinoma) is associated with oncogenic HPV, and the absence
More informationICD-9-CM to ICD-10-CM DIAGNOSIS CODE MAPPING. Central Valley Public Health: Women's Way
ICD-9-CM to ICD-10-CM DIAGNOSIS CODE MAPPING Central Valley Public Health: Women's Way ICD-9-CM (Top 35) ICD-10-CM ICD-10-CM Description COMMENTS V10.3: Personal history of malignant neoplasm of Z85.3
More informationMinimally Invasive Gynecological Surgery
Minimally Invasive Gynecological Surgery O l av Is t re Editor Minimally Invasive Gynecological Surgery Editor Olav Istre, MD, PhD Fredriksberg Denmark ISBN 978-3-662-44058-2 ISBN 978-3-662-44059-9 (ebook)
More informationuterine cancer endometrial cancer
2018 ICD-10-CM Diagnosis Code. Adenocarcinoma of endometrium ; Cancer of the. (mucous membrane that lines the endometrial cavity). ICD-10-CM C54.1 is grouped. Home ICD 9 Codes Endometrial Cancer ICD 9
More informationAtlas of Dermatology in Internal Medicine
Atlas of Dermatology in Internal Medicine wwwwwwwwwww Néstor P. Sánchez Editor Atlas of Dermatology in Internal Medicine Editor Néstor P. Sánchez Professor of Dermatology and Dermatopathology and Chairman
More informationWhen Immunostains Can Get You in Trouble: Gynecologic Pathology p16: Panacea or Pandora s Box?
When Immunostains Can Get You in Trouble: Gynecologic Pathology p16: Panacea or Pandora s Box? Teri A. Longacre, MD Stanford Medicine Stanford California pi6 in Gynecologic Pathology: Panacea or Pandora
More informationObjectives. Atypical Glandular Cells. Atypical Endocervical Cells. Reactive Endocervical Cells
2013 California Society of Pathologists 66 th Annual Meeting San Francisco, CA Atypical Glandular Cells to Early Invasive Adenocarcinoma: Cervical Cytology and Histology Christina S. Kong, MD Associate
More information3 cell types in the normal ovary
Ovarian tumors 3 cell types in the normal ovary Surface (coelomic epithelium) the origin of the great majority of ovarian tumors 90% of malignant ovarian tumors Totipotent germ cells Sex cord-stromal cells
More informationNew Developments in Immunohistochemistry for Gynecologic Pathology
New Developments in Immunohistochemistry for Gynecologic Pathology Michael T. Deavers, M.D. Professor, Departments of Pathology and Gynecologic Oncology Immunohistochemistry in Gynecologic Pathology Majority
More informationOppgave: MED5600_OPPGAVE04_V18_ORD
Side 23 av 63 Oppgave: MED5600_OPPGAVE04_V18_ORD Del 1: Sofie, 38 years, para1, comes to your office complaining about dyspareunia and spotting she has recently observed on several occasions, unrelated
More informationThe Cleveland Clinic Manual of Dynamic Endocrine Testing
The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin A. Laurence Kennedy Manjula K. Gupta Amir H. Hamrahian The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin Department of Endocrinology,
More informationCASE 4 21/07/2017. Ectopic Prostatic Tissue in Cervix. Female 31. LLETZ for borderline nuclear abnormalities
Female 31 CASE 4 LLETZ for borderline nuclear abnormalities PSA Ectopic Prostatic Tissue in Cervix AJSP 2006;30;209-215 usually incidental microscopic finding usually in ectocervical stroma? developmental
More informationGYN (Glandulars) Still Difficult After All These Years! Dina R Mody, MD Director of Cytology Laboratories and fellowship Program Methodist Hospital
GYN (Glandulars) Still Difficult After All These Years! Dina R Mody, MD Director of Cytology Laboratories and fellowship Program Methodist Hospital and Bioreference Labs (Houston) Department of Pathology
More informationHistopathology: Cervical HPV and neoplasia
Histopathology: Cervical HPV and neoplasia These presentations are to help you identify basic histopathological features. They do not contain the additional factual information that you need to learn about
More informationLESION AT PACIFIC MEDICAL COLLEGE, UDAIPUR. 1. Assistant Professor, Department of Pathology, Pacific Medical college and hospital, Udaipur.
International Journal of Medical Science and Education An official Publication of Association for Scientific and Medical Education (ASME) Original Research Article HISTOPATHOLOGICAL AND CYTOLOGICAL ANALYSIS
More informationBreast Cancer Risk Reduction and Early Detection
Breast Cancer Risk Reduction and Early Detection Edward R. Sauter Mary B. Daly Editors Breast Cancer Risk Reduction and Early Detection 123 Editors Edward R. Sauter University of North Dakota School of
More information1.Acute and Chronic Cervicitis - At the onset of menarche, the production of estrogens by the ovary stimulates maturation of the cervical and vaginal
Diseases of cervix I. Inflammations 1.Acute and Chronic Cervicitis - At the onset of menarche, the production of estrogens by the ovary stimulates maturation of the cervical and vaginal squamous mucosa
More informationCervical Dysplasia and HPV
Cervical Dysplasia and HPV J. Anthony Rakowski D.O., F.A.C.O.O.G. MSU SCS Board Review Coarse HPV Double stranded DNA virus The HPV infect epithelial cells of the skin and mucous membranes Highest risk
More informationJanuary 15, 2009 (202) PROPOSALS TO IMPROVE CYTOLOGY PROFICIENCY TESTING REQUIRED BY THE CLINICAL LABORATORY IMPROVEMENT AMENDMENTS OF 1988
DEPARTMENT OF HEALTH & HUMAN SERVICES Centers for Medicare & Medicaid Services Room 352-G 200 Independence Avenue, SW Washington, DC 20201 Office of Media Affairs CMS FACT SHEET FOR IMMEDIATE RELEASE Contact:
More informationCervical Cancer Prevention in the 21 st Century Changing Paradigms
Cervical Cancer Prevention in the 21 st Century Changing Paradigms Teresa M. Darragh, MD UCSF Departments of Pathology and Obstetrics, Gynecology & Reproductive Sciences Faculty Disclosures: Teresa M.
More informationNeurobiological Bases of Abnormal Aggression and Violent Behaviour
Neurobiological Bases of Abnormal Aggression and Violent Behaviour . József Haller Neurobiological Bases of Abnormal Aggression and Violent Behaviour József Haller Department of Behavioral Neurobiology
More information