Radiation Oncology Study Guide
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1 Radiation Oncology Study Guide For the Initial CertificationQualifying (Computer-Based) Examination General and Radiation Oncology This examination is designed to assess your understanding of the entire field of oncology and radiation oncology. Included are questions on the following topics related to cancer and cancer therapies of every type, as well as appropriate benign entities: 1. Epidemiology and pathology 2. Normal and pathologic anatomy 3. Elements of cancer diagnosis, staging, treatment (including the utilization of modalities other than radiation), and follow-up 4. Tumor markers for diagnosis and follow-up 5. Natural history and routes of local, regional, and distant spread 6. Selection of treatment modality (specific details of multimodality therapies including sequencing, interactions, and specific agents) 7. Management of both local and metastatic disease 8. Optimum radiation simulation, field design, and radiation techniques (including external beam, radiosurgery, brachytherapy, and unsealed radioactive agents) for various clinical situations 9. Tumor localization and respiratory management 10. Radiation target and organs at risk dose distribution 11. Selection of optimum radiation volume, dose, and fractionation 12. Radiation dose constraints 13. Interpreting a dose-volume histogram 14. Understanding of how radiation affects normal tissues 15. Side effects of radiation and other modalities, and how to manage them 16. Evidence-based treatment results (e.g., with surgery, radiation therapy, chemotherapy, biological therapy, or other emerginginterventions) 17. Patterns of failure 18. Palliative care 19. Precision and errors in treatment planning 20. Quality assurance 1
2 21. Patient and personnel safety 22. Bioethics 23. Biostatistics Categories for General and Radiation Oncology May include, but are not necessarily limited to: Pediatrics 1. Retinoblastoma 2. Wilms tumor 3. Neuroblastoma 4. Rhabdomyosarcoma 5. Lymphomas 6. Leukemias 7. Histocytosis X 8. Ewing sarcoma and other bone and cartilage tumors 9. Pediatric solid tumors 10. Soft-tissue sarcoma 11. Germ cell tumor 12. Hepatic tumor 13. Osteosarcoma 14. Hodgkin lymphoma Pediatric CNS Tumors 1. Medulloblastoma 2. Astrocytoma (glioma), lowgrade 3. Astrocytoma, high grade 4. Brain stem glioma 5. Ependymoma 6. Pineal/germ cell 7. Craniopharyngioma 8. Optic tract Gastrointestinal (GI) Tract 1. Esophagus 2. Stomach 3. Small bowel 4. Colon/rectum 5. Anus 6. Pancreas 7. Biliary tract 8. Liver 2
3 Gynecology 1. Cervix 2. Endometrium/uterus 3. Ovaries and fallopian tubes 4. Vagina/urethra 5. Vulva Genitourinary (GU)Tract 1. Prostate 2. Bladder 3. Testes 4. Kidneys 5. Ureter 6. Urethra 7. Penis Lymphomas and Leukemias 1. Hodgkin lymphoma 2. Non-Hodgkin lymphoma 3. Leukemia, chronic and acute 4. Multiple myeloma/plasmacytoma 5. NK/T cell lymphoma 6. Cutaneous lymphomas Head, Neck, and Skin 1. Lips 2. Larynx 3. Oral cavity 4. Oropharynx 5. Hypopharynx 6. Nasopharynx 7. Salivary glands (major and minor) 8. Orbits/eye 9. Thyroid gland 10. Paranasal sinuses 11. Skin (basal, squamous, melanoma, and Merkel) 3
4 Lung/Mediastinum 1. Non-small cell 2. Small cell 3. Superior sulcus tumor 4. Thymomas, thymic, and/or other mediastinal tumors 5. Mesothelial/pleural tumors Breast 1. Early-stage 2. Locally advanced 3. Inflammatory 4. Carcinoma in situ 5. Locally recurrent 6. Metastatic carcinoma Soft Tissue/Bone 1. Soft tissue sarcomas 2. Ewing sarcoma 3. Desmoid tumor 4. Osteosarcoma and/or chondrosarcoma 5. Other benign and malignant bone and joint tumors Central Nervous System (CNS) 1. Astrocytoma, low grade 2. Astrocytoma, high grade 3. Medulloblastoma 4. Brainstem glioma 5. Ependymoma and ependymoblastoma 6. Pineal 7. Lymphoma 8. Optic tract glioma 9. Oligodendroglioma 10. Meningioma (benign and malignant) 11. Pituitary 12. Spinal cord 13. Craniopharyngioma 14. Arteriovenous malformation (AVM) 15. Acoustic neuroma 4
5 Non-Clinical Skills A link to a detailed non-clinical skills syllabus has been provided for preparation of topics in this category: Non-clinical skills (NCS) syllabus. 1. Consent in the impaired patient 2. HIPAA issues 3. Research issues 4. General consideration Patient and personnel safety 1. Human factors related to error 2. Communication of error 3. Frequency/necessity of repeat calculations 4. General considerations Biostatistics 1. P value and significance 2. Risk ratio 3. True positive/negative 4. Meta-analysis 5. General considerations Quality assurance (QA) 1. Routine vs exceptional QA 2. QA after linacservice 3. Value of peer review 4. Root cause analysis 5. General considerations 5
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