Brain Tumor Prognosis and Prediction using Deep Belief Network

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1 Volume 119 No , ISSN: (on-line version) url: Brain Tumor Prognosis and Prediction using Deep Belief Network F.Anishya 1 S.Giridharan 2 P.Hemalatha 3 Assistant Professor, Department of IT IFET College of Engineering, Villupuram. mailtoogiri@gmail.com Assistant Professor, Department of IT IFET College of Engineering, Villupuram. anishyacse17@gmail.com M.Nivethakumari 4 Assistant Professor, Department of IT IFET College of Engineering, Villupuram. nive24it@gmail.com Assistant Professor, Department of IT IFET College of Engineering, Villupuram. hemadec4@gmail.com S.Kiruthiga 5 Assistant Professor, Department of IT IFET College of Engineering, Villupuram. cskirthi946@gmail.com Abstract: Tumor is a deadly disease it occurs when abnormal cells forms within the brain. There are two main types of tumors: malignant or cancerous tumors and benign tumors.so to overcome this issue we are in need of early precise detection of tumor cells. In conventional methods there are various algorithm which helps to diagnosis the tumor cells though it fails to predict an accurate results. This paper presents a reliable detection method based on deep mind classification algorithm is to predict the likely chances of brain related tumor diseases of the user. Deep Mind Network is one of the capable classification algorithm which employs Deep Learning approach in Deep Neural Network. This paper contains comparison of Convolution Neural Network [CNN] and Deep Mind classification [DM] algorithms. Convolution Neural Network algorithm is one of the unsupervised algorithm. It provides 82% of accuracy in the prediction of Tumor cells. But the proposed Deep Mind algorithm provides 90% accuracy in tumor cell prediction which enhances the prediction accuracy. It is designed in the MATLAB development environment. Keywords: Deep Belief Network, CNN, Brain Tumor, Deep Learning I. Introduction: Deep learning has just reformed the computer vision influencing commonsense in advances to out of what appeared like science fiction only a couple of years back. The most important issues of artificial intelligence systems is considering medical diagnosis via image processing and machine learning. The early diagnosis and prognosis of cancer detection is essential part in cancer research as it facilitates the sub-sequential clinical management of patients through machine learning techniques. Brain tumor is the abnormal growth of cells within brain. They may be distinguished into benign and malignant based upon the severity. Malignant tumor contain cancerous cells and they are difficult to remove, which may lead to death hence are more harmful than benign. MRI gives computerized view of internal body tissues. In this paper we present novel locality sensitive deep learning approaches to detect the malignant tissues where the image 3087

2 results are taken as input and pre-processing is done to classify images. Many of the innovative applications such as agricultural robot[6].deep learning applications are applied to process the real time images for predicton II. Literature survey: Dina Aboul Dahab, Samy S. A. Ghoniemy [1] proposed modified Probabilistic Neural Network (PNN) model based on learning vector quantization (LVQ) for the brain tumor classification using MRI-scans. Various image segmentation techniques are applied on MRI for detection of tumor. To classify the brain tumor there are four steps: first ROI segmentation was done to identify the boundary of tumor in MR image, then feature extraction followed by feature selection and for classifying models. The usage of discriminative features helps to classify the structural elements into normal and abnormal tissue that can reduce the complexity of the further. Finally it is concluded that the result of the present study are of great importance in the brain tumor detection which is one of the challenging tasks in the medical image processing.zaw Zaw Htike, Shoon Lei Win [2] proposed an automatic brain tumor detection and localization framework that could detect and localize brain tumor in MRI. Their proposed framework comprised of five steps: image acquisition, preprocessing, edge detection, modified histogram clustering and morphological operations. The proposed system can accurately detect and localize tumor in MRI. Through the edge detection process, the research intends to use a canny edge detector which is commonly used in similar environments. The research has also identified several medical limitations and contributions that can be done in future works. Korsuk Sirinukunwattana, Shan E Ahmed Raza [3] presented deep learning approaches sensitive to the local neighborhood for nucleus detection and classification in routine stained histology images of colorectal adeno-carcinomas. The comparison was made in favor of the proposed spatially-constrained CNN for nucleus detection and the softmax CNN, provides a better understanding of tumor micro environment. The comparison is in favor of the proposed spatially-constrained CNN for nucleus detection and the softmax CNN with the proposed neighboring ensemble predictor for nucleus classification. The combination of the two could potentially offer a systematic quantitative analysis of tissue morphology, and tissue constituents, lending itself to be a useful tool for better understanding of the tumor microenvironment. Neethu Ouseph,Shruti [4] proposed a method in tumor detection in which the target area is segmented which improves the spatial localization of image so that efficiency is improved, also consumes less time for computation. The accuracy can be further improved by using artificial neural network. The target area is segmented and the evaluation of the nature of the tumor using the tool suggested here helps the doctors in diagnosis the treatment plan making and state of the tumor monitoring. It consumes less time for computation and becomes easier to train with fewer parameters than other network. The accuracy of the system can be much more improved by using artificial neural network as the classifier.mahmoud 3088

3 Al-Ayyoub, Ghaith Husari [5] proposed Algorithms for analyzing and classifying medical images. A much higher accuracy can be achieved by gaining a better dataset with high-resolution images taken directly from the MRI scanner and also used two popular tools to achieve this, viz. ImageJ and MATLAB for extracting preprocessed images. Moreover classifier boosting techniques can be used to raise the accuracy even higher and reach a level that will allow this tool to be a significant asset to any medical facility dealing with brain tumors. III. An outline of Brain Tumor: A brain tumor occurs when a abnormal cells form within the brain cells. Normal cells grow in a controlled manner as new cells replace old or damaged ones. For reasons not fully understood, tumor cells reproduce uncontrollably. Tumor cells are named only after their cells grown. Brain is the most important part of the body organ which is composed of nerve cells and supportive tissues like glial cells and meninges. There are also some other major parts which controls the activities. They are 1.Brain Stem which helps to controls the breathing 2.Cerebellum helps to control the moving muscles to walk 3.Cerebrum which helps in sensing the sight, our memory, emotions, thinking and personality. Brain tumors can be either malignant which contain cancer cells or benign do not contain cancer cells is said to be primary brain tumor. A primary brain tumor is a tumor which begins in the brain tissue. If a cancer cell which occurs somewhere in the part of the body that spreads the cancer cells entirely and also grow in the brain. These types of tumors are called secondary or metastatic brain tumors. Brain tumors may occur at any age people. Even Researchers and doctors don t know exact cause of brain tumors. There are some Risk factors include such as exposure to ionizing radiation and family history of brain tumors. a.causes of Brain Tumor: Even a doctor neither knows what may cause a brain tumors nor how to prevent such primary tumors which starts in the brain. People m at risk for brain tumors include those who have: cancer in any part of the body prolonged exposure to pesticides, industrial solvents, and other chemicals inherited diseases, such as neurofibromatosis b. Risk Factors of Tumor Disease: Since the causes of brain tumor are highly unpredictable. Even Though there are some genetic disorders and environmental factors which may increase the tumors cells, still there are much fewer defined risk factors for brain tumors than for any other tumor cells in the body. Also the risk of increasing primary brain tumor cells is very less. The American Cancer Society has estimated the risk factor of tumor cells over a period of lifetime is less than 1%. It is also highly important to notice that a brain tumor risk factor affects only the probability of increasing brain tumor cells over a life time. C. Tumor prediction and Detection System: There is some other method that could deal with representation learning by automatically learning a Hierarchy of growing complex features directly from data that is known as Deep Learning. So need to concentrate highly on designing architectures instead of developing handcrafted features which may require 3089

4 specialized knowledge. Convolution Neural Networks have been used for several object recognition and biological image segmentation challenges. Still a CNN used to operates over patches using kernels. problems where the information is highly structured like an image of a brain scan. In other words it is difficult to depict the patterns they find to a human being. IV. Enhanced Tumor Prediction System A. DEEP LEARNING: Deep learning, a detachment of machine learning. Deep learning utilizes a hierarchical level of artificial neural networks to carry out the machine learning process. By default the artificial neural networks are built like a human brain with neuron nodes connected together like a network. While conventional programs build analysis with data in a linear way where as the hierarchical function of deep learning method enables the machines to process information with a non-linear approach. There might be so many hidden layers in between the input layer as well as output layer and these are used to extract more information by exploiting structure in the data. A network is considered as deep when it has more than one hidden layer. Neural networks are great at solving Fig 4.2 Deep Learning Architecture B.DEEP BELIEF NETWORK Deep Belief Networks are graphical models which trained to pull out a deep hierarchical depiction of the training data. It is a generative graphical model of multiple layers of latent variables which associates between the layers but not struck between units within each single layer. While training on a set of samples in an unsupervised way Deep Belief Network can able to learn and probabilistically it could reconstruct its inputs. Similarly to perception and back propagation neural networks Deep Belief Network is unsupervised learning algorithm. A conviction belief network is composed stochastic of binary units with weighted connections.in some works[26] explicate error-rate (ER) results of transmitter preprocessing (TP) aided coded multi-carrier (MC)-interleave-division-multiple-access (IDMA) scheme for co-operative downlink (DL) communication is proposed to minimize the error rate. This enhanced architecture has two convolution and three fully-connected layers. This architecture also prevents over fitting. 3090

5 Classification of features is obtained after the convolution layer since the last three layers are fully connected. C.TRAINING PHASES There are two basic primarily used basic approaches they are: Feature Selection Auto Encoder Phase-1: While we decided to train our data in unsupervised learning phase the first thing is to do is Feature selection. This feature selection method is used to select attributes from the whole datasets. Phase-2: Here two layers are considered one is visible and other is hidden. Visible layers correspond to the data and hidden layer correspond to inherent features of the data. The major difference is in Boltzmann hidden units are considered as latent random variables and in auto encoders are considers computational nodes. D.DEEP LEARNING TRAINING Step 1: Convolution layer Here a dot product is computed at each sub region of the input data with its kernel and the results are obtained from the output of this convolution layer. This layer is to parameterized by the size and number of kernels, width and height dimensions of the layer and non linearity is applied to activate a functions. Step 2: Max-pooling layer In order to reduce the feature size it performs down sampling operation. It considers small blocks of data and generates a singular output for each block. This layer follows a convolution layer and performs a down sampling operation in order to reduce the feature size. It considers only small rectangular blocks of the data and generates only a singular output for each and every block. This can be done in various ways, but one thing is that it takes maximum in the block. Hence if the block size is 2 2, then the number of features will be reduced by 4 times. Step 3: Auto encoder It is a symmetrical neural network mainly used for unsupervised feature learning. The training is given by reconstructing the error between the input data and reconstruction at the output layer. Hidden layers are activated corresponding to the input data. Step 4: Restricted Boltzmann Machine Restricted Boltzmann Machine consists of two-layer bipartite graphical model with a set of visible unit s v, and set of hidden units h, symmetrical connections between these two layers represented by a weight matrix W. E. DEEP LEARNING CLASSIFICATION At last, after several convolution and maxpooling layers, the features obtained are transformed into a distinct one-dimensional vector that is also used for the classification. Layers are fully connected in classification and use only one output unit per class label. The gradient based learning and Deep Belief Network algorithm are useful for getting the accurate percentage level of tumor cells. It is highly important that to initialize all weights to small random values in Deep neural network. To train deep networks iterative gradient based optimization. V.EXPERIMENTAL RESULTS INPUT: 3091

6 CLASSIFICATION CLASS1: Fig 5.1 Input image Fig 5.4 classification Class1 FILTERED IMAGE: Fig 5.5 Filtered Image CONCLUSION Fig 5.2 Locating bounding box SEGMENTED TUMOR Fig 5.3 Segmented Tumor detected In this work we have enhanced a way to do brain tumor segmentation with deep neural networks. With this deep belief network classification method introduces the deep learning approach for the prediction of likelihood percentage of Tumor disease. The enhanced work focuses for the prediction of tumor cells. Deep Belief architecture has more number of hidden layers. So using these accurate results is obtained. While compare to CNN algorithm DBN classifier gives 90% accuracy. REFERENCES 1. Natarajan P, Krishnan.N, Natasha Sandeep Kenkre, Shraiya Nancy, Bhuvanesh Pratap Singh, "Tumor Detection using threshold operation in MRI Brain Images", IEEE International Conference on Computational 3092

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