ICD-10 and Radiation Oncology

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1 ICD-10 and Radiation Oncology Steven M. Verno, CEMCS

2 ICD-10 and Radiation Oncology Steven M. Verno, CEMCS September 23, 2008 Note: ICD-9-CM and ICD-10 are owned and copyrighted by the World Health Organization. The codes in this guide were obtained from the US Department of Health and Human Services, NCHS website. For at least the past twenty (20) + years, we have learned and used ICD-9-CM when coding for our providers. As someone once said, just when we learned the answers, they changed the questions. Also, for years, there has been rumor that ICD-10 would be replacing ICD-9, and now this will soon be a reality. According to the Code of Federal Regulations, specifically, 45 CFR Parts 160 and 162, Titled HIPAA Administrative Simplification: Modification to Medical Data Code Set Standards To Adopt ICD 10 CM and ICD 10 PCS; Proposed Rule, dated August 22, 2008: We propose October 1, 2011 as the compliance date for ICD 10 CM and ICD 10 PCS code sets for all covered entities. It is important to note that the compliance date must occur on October 1 in order to coincide with the effective date of annual Medicare inpatient PPS updates. There is an old saying in coding, If it isn t documented, it doesn t exist or it didn t happen. When ICD- 10 becomes effective, it s success is dependent on the provider s documentation. If the documentation shows, OM, many of us know this means Otitis Media. Under ICD-9-CM, you have the following codes for OM: ICD-10 will require more work on the provider to document the exact type of diagnosis found with the patient. ICD-10 opens more with the anatomical area affected and allows for coding of chronic modalities. Lets look at some of the most used codes in the Radiation Oncology with the ICD-10-CM Instructions Note: Functional activity All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm. Morphology [Histology]

3 Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma, the morphology (histologic type) is included in the category and codes. To identify the morphology for the majority of Chapter 2 codes that do not include the histologic type, comprehensive separate morphology codes are provided. These morphology codes are derived from the second edition of the International Classification of Diseases for Oncology (ICD-O). The correct morphology code can be found in the Alphabetic Index to Diseases under the main and subterm term for the type of neoplasm, adenocarcinoma, sarcoma, etc. Primary malignant neoplasms overlapping site boundaries A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code.8 ("overlapping lesion"), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned. Malignant neoplasm of ectopic tissue Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9). Malignant neoplasms (C00-C96) Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, hematopoietic and related tissue (C00-C75) ICD-9-CM (Malignant neoplasm of other and ill-defined sites, Abdomen) ICD-10 C76.2 Malignant neoplasm of abdomen (Needs more info on anatomical body within abdomen affected with neoplasm) ICD-9-CM 2) (Malignant neoplasm of kidney and other and unspecified urinary organs Icd-10 C64 Malignant neoplasm of kidney, except renal pelvis Excludes1: malignant neoplasm of renal calyces (C65.-) malignant neoplasm of renal pelvis (C65.-) C64.0 Malignant neoplasm of right kidney, except renal pelvis C64.1 Malignant neoplasm of left kidney, except renal pelvis C64.9 Malignant neoplasm of kidney, except renal pelvis, unspecified side Under ICD-10, organs must be identified.

4 ICD-9-CM (Malignant neoplasm of female breast, Breast (female), unspecified) ICD-10 C50 Malignant neoplasm of breast Requires more anatomical information (Malignant neoplasm of gallbladder and extrahepatic bile ducts, Gallbladder) C23 Malignant neoplasm of gallbladder (Malignant neoplasm of thymus, heart, and mediastinum, heart) C38.0 Malignant neoplasm of heart (Code does not exist in 2008) (Malignant neoplasm of liver and intrahepatic bile ducts, Liver) C22 Malignant neoplasm of liver and intrahepatic bile ducts C22.0 Liver cell carcinoma (Malignant neoplasm of trachea, bronchus, and lung, Bronchus and lung, unspecified) C34 Malignant neoplasm of bronchus and lung (Malignant neoplasm of ovary and other uterine adnexa, Ovary) C56 Malignant neoplasm of ovary Use additional code to identify any functional activity C56.0 Malignant neoplasm of right ovary C56.1 Malignant neoplasm of left ovary C56.9 Malignant neoplasm of ovary, unspecified side Other Neoplasm ICD-19-CM Codes are as follows: Malignant neoplasms (C00-C96) Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, hematopoietic and related tissue (C00-C75)

5 Malignant neoplasm of lip, oral cavity and pharynx (C00C14) C00 Malignant neoplasm of lip Excludes1: malignant neoplasm of skin of lip (C43.0, C44.0) Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C00.0 Malignant neoplasm of external upper lip Malignant neoplasm of lipstick area of upper lip Malignant neoplasm of upper lip NOS Malignant neoplasm of vermilion border of upper lip C00.1 Malignant neoplasm of external lower lip Malignant neoplasm of lower lip NOS Malignant neoplasm of lipstick area of lower lip Malignant neoplasm of vermilion border of lower lip C00.2 Malignant neoplasm of external lip, unspecified Malignant neoplasm of vermilion border of lip NOS C00.3 Malignant neoplasm of upper lip, inner aspect Malignant neoplasm of buccal aspect of upper lip Malignant neoplasm of frenulum of upper lip Malignant neoplasm of mucosa of upper lip Malignant neoplasm of oral aspect of upper lip C00.4 Malignant neoplasm of lower lip, inner aspect Malignant neoplasm of buccal aspect of lower lip Malignant neoplasm of frenulum of lower lip Malignant neoplasm of mucosa of lower lip Malignant neoplasm of oral aspect of lower lip C00.5 Malignant neoplasm of lip, unspecified, inner aspect Malignant neoplasm of buccal aspect of lip, unspecified Malignant neoplasm of frenulum of lip, unspecified Malignant neoplasm of mucosa of lip, unspecified Malignant neoplasm of oral aspect of lip, unspecified C00.6 Malignant neoplasm of commissure of lip, unspecified C00.8 Malignant neoplasm of overlapping sites of lip C00.9 Malignant neoplasm of lip, unspecified C01 Malignant neoplasm of base of tongue Includes: malignant neoplasm of dorsal surface of base of tongue malignant neoplasm of fixed part of tongue NOS malignant neoplasm of posterior third of tongue Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C02 Malignant neoplasm of other and unspecified parts of tongue Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C02.0 Malignant neoplasm of dorsal surface of tongue Malignant neoplasm of anterior two-thirds of tongue, dorsal surface Excludes2: malignant neoplasm of dorsal surface of base of tongue (C01) C02.1 Malignant neoplasm of border of tongue Malignant neoplasm of tip of tongue

6 C02.2 Malignant neoplasm of ventral surface of tongue Malignant neoplasm of anterior two-thirds of tongue, ventral surface Malignant neoplasm of frenulum linguae C02.3 Malignant neoplasm of anterior two-thirds of tongue, part unspecified Malignant neoplasm of middle third of tongue NOS Malignant neoplasm of mobile part of tongue NOS C02.4 Malignant neoplasm of lingual tonsil Excludes2: malignant neoplasm of tonsil NOS (C09.9) C02.8 Malignant neoplasm of overlapping sites of tongue Malignant neoplasm of two or more contiguous sites of tongue C02.9 Malignant neoplasm of tongue, unspecified C03 Malignant neoplasm of gum Includes: malignant neoplasm of alveolar (ridge) mucosa malignant neoplasm of gingiva Excludes2: malignant odontogenic neoplasms (C41.0-C41.1) Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C03.0 Malignant neoplasm of upper gum C03.1 Malignant neoplasm of lower gum C03.9 Malignant neoplasm of gum, unspecified C04 Malignant neoplasm of floor of mouth Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C04.0 Malignant neoplasm of anterior floor of mouth Malignant neoplasm of anterior to the premolar-canine junction C04.1 Malignant neoplasm of lateral floor of mouth C04.8 Malignant neoplasm of overlapping sites of floor of mouth C04.9 Malignant neoplasm of floor of mouth, unspecified C05 Malignant neoplasm of palate Excludes1: Kaposi's sarcoma of palate (C46.2) Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0) C05.0 Malignant neoplasm of hard palate C05.1 Malignant neoplasm of soft palate Excludes2: malignant neoplasm of nasopharyngeal surface of soft palate (C11.3) C05.2 Malignant neoplasm of uvula C05.8 Malignant neoplasm of overlapping sites of palate C05.9 Malignant neoplasm of palate, unspecified Malignant neoplasm of roof of mouth C06 Malignant neoplasm of other and unspecified parts of mouth Use additional code to identify: alcohol abuse and dependence (F10.-) history of tobacco use (Z87.82) tobacco dependence (F17.-) tobacco use (Z72.0)

7 C06.0 Malignant neoplasm of cheek mucosa Malignant neoplasm of buccal mucosa NOS Malignant neoplasm of internal cheek C06.1 Malignant neoplasm of vestibule of mouth Malignant neoplasm of buccal sulcus (upper) (lower) Malignant neoplasm of labial sulcus (upper) (lower) C06.2 Malignant neoplasm of retromolar area C06.8 Malignant neoplasm of overlapping sites of other and unspecified parts of mouth C06.80 Malignant neoplasm of overlapping sites of unspecified parts of mouth C06.89 Malignant neoplasm of overlapping sites of other parts of mouth "book leaf" neoplasm [ventral surface of tongue and floor of mouth] C06.9 Malignant neoplasm of mouth, unspecified Malignant neoplasm of minor salivary gland, unspecified side Malignant neoplasm of oral cavity NOS C07 Malignant neoplasm of parotid gland Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C08 Malignant neoplasm of other and unspecified major salivary glands Includes: malignant neoplasm of salivary ducts Excludes1: malignant neoplasms of specified minor salivary glands which are classified according to their anatomical location Excludes2: malignant neoplasms of minor salivary glands NOS (C06.9) malignant neoplasm of parotid gland (C07) Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C08.0 Malignant neoplasm of submandibular gland Malignant neoplasm of submaxillary gland

8 C08.1 Malignant neoplasm of sublingual gland C08.9 Malignant neoplasm of major salivary gland, unspecified Malignant neoplasm of salivary gland (major) NOS C09 Malignant neoplasm of tonsil Excludes2: malignant neoplasm of lingual tonsil (C02.4) malignant neoplasm of pharyngeal tonsil (C11.1) Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C09.0 Malignant neoplasm of tonsillar fossa C09.1 Malignant neoplasm of tonsillar pillar (anterior) (posterior) C09.8 Malignant neoplasm of overlapping sites of tonsil C09.9 Malignant neoplasm of tonsil, unspecified Malignant neoplasm of tonsil NOS Malignant neoplasm of faucial tonsils Malignant neoplasm of palatine tonsils C10 Malignant neoplasm of oropharynx Excludes2: malignant neoplasm of tonsil (C09.-) Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C10.0 Malignant neoplasm of vallecula C10.1 Malignant neoplasm of anterior surface of epiglottis Malignant neoplasm of epiglottis, free border [margin] Malignant neoplasm of glossoepiglottic fold(s) Excludes2: malignant neoplasm of epiglottis (suprahyoid portion) NOS (C32.1) C10.2 Malignant neoplasm of lateral wall of oropharynx C10.3 Malignant neoplasm of posterior wall of oropharynx C10.4 Malignant neoplasm of branchial cleft Malignant neoplasm of branchial cyst [site of neoplasm] C10.8 Malignant neoplasm of overlapping sites of oropharynx Malignant neoplasm of junctional region of oropharynx C10.9 Malignant neoplasm of oropharynx, unspecified

9 C11 Malignant neoplasm of nasopharynx Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C11.0 Malignant neoplasm of superior wall of nasopharynx Malignant neoplasm of roof of nasopharynx C11.1 Malignant neoplasm of posterior wall of nasopharynx Malignant neoplasm of adenoid Malignant neoplasm of pharyngeal tonsil C11.2 Malignant neoplasm of lateral wall of nasopharynx Malignant neoplasm of fossa of Rosenmüller Malignant neoplasm of opening of auditory tube Malignant neoplasm of pharyngeal recess C11.3 Malignant neoplasm of anterior wall of nasopharynx Malignant neoplasm of floor of nasopharynx Malignant neoplasm of nasopharyngeal (anterior) (posterior) surface of soft palate Malignant neoplasm of posterior margin of nasal choana Malignant neoplasm of posterior margin of nasal septum C11.8 Malignant neoplasm of overlapping sites of nasopharynx C11.9 Malignant neoplasm of nasopharynx, unspecified Malignant neoplasm of nasopharyngeal wall NOS C12 Malignant neoplasm of pyriform sinus Includes: malignant neoplasm of pyriform fossa Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C13 Malignant neoplasm of hypopharynx Excludes2: malignant neoplasm of pyriform sinus (C12) Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0)

10 C13.0 Malignant neoplasm of postcricoid region C13.1 Malignant neoplasm of aryepiglottic fold, hypopharyngeal aspect Malignant neoplasm of aryepiglottic fold NOS Malignant neoplasm of interarytenoid fold NOS Malignant neoplasm of aryepiglottic fold marginal zone Malignant neoplasm of interarytenoid fold marginal zone Excludes2: malignant neoplasm of aryepiglottic fold or interarytenoid fold, laryngeal aspect (C32.1) C13.2 Malignant neoplasm of posterior wall of hypopharynx C13.8 Malignant neoplasm of overlapping sites of hypopharynx C13.9 Malignant neoplasm of hypopharynx, unspecified Malignant neoplasm of hypopharyngeal wall NOS C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx Excludes1: malignant neoplasm of oral cavity NOS (C06.9) Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C14.0 Malignant neoplasm of pharynx, unspecified C14.2 Malignant neoplasm of Waldeyer's ring C14.8 Malignant neoplasm of overlapping sites of lip, oral cavity and pharynx Primary malignant neoplasm of two or more contiguous sites of lip, oral cavity and pharynx Excludes1: "book leaf" neoplasm [ventral surface of tongue and floor of mouth] (C06.89) Malignant neoplasm of digestive organs (C15-C26) Excludes1: Kaposi's sarcoma of gastrointestinal sites (C46.4) C15 Malignant neoplasm of esophagus Use additional code to identify: alcohol abuse and dependence (F10.-) C15.3 Malignant neoplasm of upper third of esophagus C15.4 Malignant neoplasm of middle third of esophagus C15.5 Malignant neoplasm of lower third of esophagus Excludes1: malignant neoplasm of cardio-esophageal junction (C16.0) C15.8 Malignant neoplasm of overlapping sites of esophagus C15.9 Malignant neoplasm of esophagus, unspecified C16 Malignant neoplasm of stomach

11 Use additional code to identify: alcohol abuse and dependence (F10.-) Excludes1: malignant stromal tumor of stomach (C49.4) C16.0 Malignant neoplasm of cardia Malignant neoplasm of cardiac orifice Malignant neoplasm of cardio-esophageal junction Malignant neoplasm of esophagus and stomach Malignant neoplasm of gastro-esophageal junction C16.1 Malignant neoplasm of fundus of stomach C16.2 Malignant neoplasm of body of stomach C16.3 Malignant neoplasm of pyloric antrum Malignant neoplasm of gastric antrum C16.4 Malignant neoplasm of pylorus Malignant neoplasm of prepylorus Malignant neoplasm of pyloric canal C16.5 Malignant neoplasm of lesser curvature of stomach, unspecified Malignant neoplasm of lesser curvature of stomach, not classifiable to C16.1-C16.4 C16.6 Malignant neoplasm of greater curvature of stomach, unspecified Malignant neoplasm of greater curvature of stomach, not classifiable to C16.0-C16.4 C16.8 Malignant neoplasm of overlapping sites of stomach C16.9 Malignant neoplasm of stomach, unspecified Gastric cancer NOS C17 Malignant neoplasm of small intestine Excludes1: malignant stromal tumor of small intestine (C49.4) C17.0 Malignant neoplasm of duodenum C17.1 Malignant neoplasm of jejunum C17.2 Malignant neoplasm of ileum Excludes1: malignant neoplasm of ileocecal valve (C18.0) C17.3 Meckel's diverticulum C17.8 Malignant neoplasm of overlapping sites of small intestine C17.9 Malignant neoplasm of small intestine, unspecified C18 Malignant neoplasm of colon C18.0 Malignant neoplasm of cecum Malignant neoplasm of ileocecal valve C18.1 Malignant neoplasm of appendix C18.2 Malignant neoplasm of ascending colon C18.3 Malignant neoplasm of hepatic flexure C18.4 Malignant neoplasm of transverse colon C18.5 Malignant neoplasm of splenic flexure C18.6 Malignant neoplasm of descending colon C18.7 Malignant neoplasm of sigmoid colon Malignant neoplasm of sigmoid (flexure) Excludes1: malignant neoplasm of rectosigmoid junction (C19) C18.8 Malignant neoplasm of overlapping sites of colon

12 C18.9 Malignant neoplasm of colon, unspecified Malignant neoplasm of large intestine NOS C19 Malignant neoplasm of rectosigmoid junction Includes: malignant neoplasm of colon with rectum malignant neoplasm of rectosigmoid (colon) C20 Malignant neoplasm of rectum Includes: malignant neoplasm of rectal ampulla C21 Malignant neoplasm of anus and anal canal Excludes2: malignant melanoma of anal margin (C43.51) malignant melanoma of anal skin (C43.51) malignant melanoma of perianal skin (C43.51) malignant neoplasm of anal margin (C44.51) malignant neoplasm of anal skin (C44.51) malignant neoplasm of perianal skin (C44.51) C21.0 Malignant neoplasm of anus, unspecified C21.1 Malignant neoplasm of anal canal Malignant neoplasm of anal sphincter C21.2 Malignant neoplasm of cloacogenic zone C21.8 Malignant neoplasm of overlapping sites of rectum, anus and anal canal Malignant neoplasm of anorectal junction Malignant neoplasm of anorectum Primary malignant neoplasm of two or more contiguous sites of rectum,anus and anal canal C22 Malignant neoplasm of liver and intrahepatic bile ducts Excludes1: malignant neoplasm of biliary tract NOS (C24.9) secondary malignant neoplasm of liver (C78.7) Use additional code to identify: alcohol abuse and dependence (F10.-) hepatitis B (B16.-, B18.0-B18.1) hepatitis C (B17.1-, B18.2) C22.0 Liver cell carcinoma Hepatocellular carcinoma Hepatoma C22.1 Intrahepatic bile duct carcinoma Cholangiocarcinoma Excludes1: malignant neoplasm of hepatic duct (C24.0) C22.2 Hepatoblastoma C22.3 Angiosarcoma of liver Kupffer cell sarcoma C22.4 Other sarcomas of liver C22.7 Other specified carcinomas of liver

13 C22.8 Malignant neoplasm of liver, primary, unspecified as to type C22.9 Malignant neoplasm of liver, not specified as primary or secondary C23 Malignant neoplasm of gallbladder C24 Malignant neoplasm of other and unspecified parts of biliary tract Excludes1: malignant neoplasm of intrahepatic bile duct (C22.1) C24.0 Malignant neoplasm of extrahepatic bile duct Malignant neoplasm of biliary duct or passage NOS Malignant neoplasm of common bile duct Malignant neoplasm of cystic duct Malignant neoplasm of hepatic duct C24.1 Malignant neoplasm of ampulla of Vater C24.8 Malignant neoplasm of overlapping sites of biliary tract Malignant neoplasm involving both intrahepatic and extrahepatic bile ducts Primary malignant neoplasm of two or more contiguous sites of biliary tract C24.9 Malignant neoplasm of biliary tract, unspecified C25 Malignant neoplasm of pancreas Use additional code to identify: alcohol abuse and dependence (F10.-) C25.0 Malignant neoplasm of head of pancreas C25.1 Malignant neoplasm of body of pancreas C25.2 Malignant neoplasm of tail of pancreas C25.3 Malignant neoplasm of pancreatic duct C25.4 Malignant neoplasm of endocrine pancreas Malignant neoplasm of islets of Langerhans Use additional code to identify any functional activity. C25.7 Malignant neoplasm of other parts of pancreas Malignant neoplasm of neck of pancreas C25.8 Malignant neoplasm of overlapping sites of pancreas C25.9 Malignant neoplasm of pancreas, unspecified C26 Malignant neoplasm of other and ill-defined digestive organs Excludes1: malignant neoplasm of peritoneum and retroperitoneum (C48.-) C26.0 Malignant neoplasm of intestinal tract, part unspecified Malignant neoplasm of intestine NOS C26.1 Malignant neoplasm of spleen Excludes1: Hodgkin's disease (C81.-) non-hodgkin's lymphoma (C82-C85) C26.9 Malignant neoplasm of ill-defined sites within the digestive system Malignant neoplasm of alimentary canal or tract NOS Malignant neoplasm of gastrointestinal tract NOS Excludes1: malignant neoplasm of abdominal NOS (C76.2) malignant neoplasm of intra-abdominal NOS (C76.2)

14 Malignant neoplasm of respiratory and intrathoracic organs (C30-C39) Includes: malignant neoplasm of middle ear Excludes1: mesothelioma (C45.-) C30 Malignant neoplasm of nasal cavity and middle ear C30.0 Malignant neoplasm of nasal cavity Malignant neoplasm of cartilage of nose Malignant neoplasm of nasal concha Malignant neoplasm of internal nose Malignant neoplasm of septum of nose Malignant neoplasm of vestibule of nose Excludes1: malignant neoplasm of nasal bone (C41.0) malignant neoplasm of nose NOS (C76.0) malignant neoplasm of olfactory bulb (C72.2-) malignant neoplasm of posterior margin of nasal septum and choana (C11.3) malignant neoplasm of skin of nose (C43.31, C44.31) malignant neoplasm of turbinates (C41.0) C30.1 Malignant neoplasm of middle ear Malignant neoplasm of antrum tympanicum Malignant neoplasm of auditory tube Malignant neoplasm of eustachian tube Malignant neoplasm of inner ear Malignant neoplasm of mastoid air cells Malignant neoplasm of tympanic cavity Excludes1: malignant neoplasm of auricular canal (external) (C43.2, C44.2-) malignant neoplasm of bone of ear (meatus) (C41.0) malignant neoplasm of cartilage of ear (C49.0) malignant neoplasm of skin of (external) ear (C43.2-, C44.2-) C31 Malignant neoplasm of accessory sinuses C31.0 Malignant neoplasm of maxillary sinus Malignant neoplasm of antrum (Highmore) (maxillary) C31.1 Malignant neoplasm of ethmoidal sinus C31.2 Malignant neoplasm of frontal sinus C31.3 Malignant neoplasm of sphenoid sinus C31.8 Malignant neoplasm of overlapping sites of accessory sinuses C31.9 Malignant neoplasm of accessory sinus, unspecified

15 C32 Malignant neoplasm of larynx Use additional code to identify: alcohol abuse and dependence (F10.-) exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C32.0 Malignant neoplasm of glottis Malignant neoplasm of intrinsic larynx Malignant neoplasm of laryngeal commissure (anterior)(posterior) Malignant neoplasm of vocal cord (true) NOS C32.1 Malignant neoplasm of supraglottis Malignant neoplasm of aryepiglottic fold or interarytenoid fold, laryngeal aspect Malignant neoplasm of epiglottis (suprahyoid portion) NOS Malignant neoplasm of extrinsic larynx Malignant neoplasm of false vocal cord Malignant neoplasm of posterior (laryngeal) surface of epiglottis Malignant neoplasm of ventricular bands Excludes2: malignant neoplasm of anterior surface of epiglottis (C10.1) Malignant neoplasm of aryepiglottic fold or interarytenoid fold: NOS (C13.1) hypopharyngeal aspect (C13.1) marginal zone (C13.1) C32.2 Malignant neoplasm of subglottis C32.3 Malignant neoplasm of laryngeal cartilage C32.8 Malignant neoplasm of overlapping sites of larynx C32.9 Malignant neoplasm of larynx, unspecified C33 Malignant neoplasm of trachea Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C34 Malignant neoplasm of bronchus and lung Excludes1: Kaposi's sarcoma of lung (C46.5-) Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0)

16 C34.0 Malignant neoplasm of main bronchus Malignant neoplasm of carina Malignant neoplasm of hilus (of lung) C34.00 Malignant neoplasm of main bronchus, unspecified side C34.01 Malignant neoplasm of right main bronchus C34.02 Malignant neoplasm of left main bronchus C34.1 Malignant neoplasm of upper lobe, bronchus or lung C34.10 Malignant neoplasm of upper lobe, bronchus or lung, unspecified side C34.11 Malignant neoplasm of upper lobe, right bronchus or lung C34.12 Malignant neoplasm of upper lobe, left bronchus or lung C34.2 Malignant neoplasm of middle lobe, right bronchus or lung C34.3 Malignant neoplasm of lower lobe, bronchus or lung C34.30 Malignant neoplasm of lower lobe, bronchus or lung, unspecified side C34.31 Malignant neoplasm of lower lobe, right bronchus or lung C34.32 Malignant neoplasm of lower lobe, left bronchus or lung C34.8 Malignant neoplasm of overlapping sites of bronchus and lung C34.80 Malignant neoplasm of overlapping sites of bronchus and lung, unspecified side C34.81 Malignant neoplasm of overlapping sites of right bronchus and lung C34.82 Malignant neoplasm of overlapping sites of left bronchus and lung C34.9 Malignant neoplasm of bronchus or lung, unspecified C34.90 Malignant neoplasm of bronchus or lung, unspecified, unspecified side C34.91 Malignant neoplasm of right bronchus or lung, unspecified C34.92 Malignant neoplasm of left bronchus or lung, unspecified C37 Malignant neoplasm of thymus C38 Malignant neoplasm of heart, mediastinum and pleura Excludes1: mesothelioma (C45.-) C38.0 Malignant neoplasm of heart Malignant neoplasm of pericardiumexcludes1: malignant neoplasm of great vessels (C49.3) C38.1 Malignant neoplasm of anterior mediastinum C38.2 Malignant neoplasm of posterior mediastinum C38.3 Malignant neoplasm of mediastinum, part unspecified C38.4 Malignant neoplasm of pleura C38.8 Malignant neoplasm of overlapping sites of heart, mediastinum and pleura

17 C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs Excludes1: intrathoracic malignant neoplasm NOS (C76.1) thoracic malignant neoplasm NOS (C76.1) Use additional code to identify: exposure to environmental tobacco smoke (Z58.7) exposure to tobacco smoke in the perinatal period (P96.81) history of tobacco use (Z87.82) occupational exposure to environmental tobacco smoke (Z57.31) tobacco dependence (F17.-) tobacco use (Z72.0) C39.0 Malignant neoplasm of upper respiratory tract, part unspecified C39.9 Malignant neoplasm of lower respiratory tract, part unspecified Malignant neoplasm of respiratory tract NOS Malignant neoplasm of bone and articular cartilage (C40C41) Includes: malignant neoplasm of cartilage (articular) (joint) malignant neoplasm of periosteum Excludes1: malignant neoplasm of bone marrow NOS (C96.8) malignant neoplasm of synovia (C49.- C40 Malignant neoplasm of bone and articular cartilage of limbs Use additional code to identify major osseous defect, if applicable (M89.7-) C40.0 Malignant neoplasm of scapula and long bones of upper limb C40.00 Malignant neoplasm of scapula and long bones of upper limb, unspecified side C40.01 Malignant neoplasm of scapula and long bones of right upper limb C40.02 Malignant neoplasm of scapula and long bones of left upper limb C40.1 Malignant neoplasm of short bones of upper limb C40.10 Malignant neoplasm of short bones of upper limb, unspecified side C40.11 Malignant neoplasm of short bones of right upper limb C40.12 Malignant neoplasm of short bones of left upper limb C40.2 Malignant neoplasm of long bones of lower limb C40.20 Malignant neoplasm of long bones of lower limb, unspecified side C40.21 Malignant neoplasm of long bones of right lower limb C40.22 Malignant neoplasm of long bones of left lower limb C40.3 Malignant neoplasm of short bones of lower limb C40.30 Malignant neoplasm of short bones of lower limb, unspecified side C40.31 Malignant neoplasm of short bones of right lower limb C40.32 Malignant neoplasm of short bones of left lower limb

18 C40.8 Malignant neoplasm of overlapping sites of bone and articular cartilage of limb C40.80 Malignant neoplasm of overlapping sites of bone and articular cartilage of limb, unspecified side C40.81 Malignant neoplasm of overlapping sites of bone and articular cartilage of right limb C40.82 Malignant neoplasm of overlapping sites of bone and articular cartilage of left limb C40.9 Malignant neoplasm of bones and articular cartilage of limb, unspecified C40.90 Malignant neoplasm of bones and articular cartilage of limb, unspecified, unspecified side C40.91 Malignant neoplasm of bones and articular cartilage of right limb, unspecified C40.92 Malignant neoplasm of bones and articular cartilage of left limb, unspecified C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites Excludes1: malignant neoplasm of bones of limbs (C40.-) malignant neoplasm of cartilage of: ear (C49.0) eyelid (C49.0) larynx (C32.3) limbs (C40.-) nose (C30.0) C41.0 Malignant neoplasm of bones of skull and face Malignant neoplasm of maxilla (superior) Malignant neoplasm of orbital bone Excludes2: carcinoma, any type except intraosseous or odontogenic of: maxillary sinus (C31.0) upper jaw (C03.0) malignant neoplasm of jaw bone (lower) (C41.1) C41.1 Malignant neoplasm of mandible Malignant neoplasm of inferior maxilla Malignant neoplasm of lower jaw bone Excludes2: carcinoma, any type except intraosseous or odontogenic of:jaw NOS (C03.9) lower (C03.1) malignant neoplasm of upper jaw bone (C41.0) C41.2 Malignant neoplasm of vertebral column Excludes1: malignant neoplasm of sacrum and coccyx (C41.4) C41.3 Malignant neoplasm of ribs, sternum and clavicle C41.4 Malignant neoplasm of pelvic bones, sacrum and coccyx C41.9 Malignant neoplasm of bone and articular cartilage, unspecified Melanoma and other malignant neoplasms of skin

19 (C43C44) Excludes1: melanoma in situ (D03.-) C43 Malignant melanoma of skin Use additional morphology codes M872-M879 with behavior code /3 Excludes2: malignant melanoma of skin of genital organs (C51-C52, C60.-, C63.-) sites other than skin-code to malignant neoplasm of the site C43.0 Malignant melanoma of lip Excludes1: malignant neoplasm of vermilion border of lip (C00.0-C00.2) C43.1 Malignant melanoma of eyelid, including canthus C43.10 Malignant melanoma of eyelid, including canthus, unspecified side C43.11 Malignant melanoma of right eyelid, including canthus C43.12 Malignant melanoma of left eyelid, including canthus C43.2 Malignant melanoma of ear and external auricular canal C43.20 Malignant melanoma of ear and external auricular canal, unspecified side C43.21 Malignant melanoma of right ear and external auricular canal C43.22 Malignant melanoma of left ear and external auricular canal C43.3 Malignant melanoma of other and unspecified parts of face C43.30 Malignant melanoma of unspecified part of face C43.31 Malignant melanoma of nose C43.39 Malignant melanoma of other parts of face C43.4 Malignant melanoma of scalp and neck C43.5 Malignant melanoma of trunk Excludes2: malignant neoplasm of anus NOS (C21.0) malignant neoplasm of scrotum (C63.2) C43.51 Malignant melanoma of anal skin Malignant melanoma of anal margin Malignant melanoma of perianal skin C43.52 Malignant melanoma of skin of breast C43.59 Malignant melanoma of other part of trunk C43.6 Malignant melanoma of upper limb, including shoulder C43.60 Malignant melanoma of upper limb, including shoulder, unspecified side C43.61 Malignant melanoma of right upper limb, including shoulder C43.62 Malignant melanoma of left upper limb, including shoulder C43.7 Malignant melanoma of lower limb, including hip C43.70 Malignant melanoma of lower limb, including hip, unspecified side C43.71 Malignant melanoma of right lower limb, including hip C43.72 Malignant melanoma of left lower limb, including hip C43.8 Overlapping malignant melanoma of skin C43.9 Malignant melanoma of skin, unspecified

20 Melanoma (malignant) NOS C44 Other malignant neoplasm of skin Includes: malignant neoplasm of sebaceous glands malignant neoplasm of sweat glands Excludes1: Kaposi's sarcoma of skin (C46.0) malignant melanoma of skin (C43.-) malignant neoplasm of skin of genital organs (C51-C52, C60.-, C63.2) C44.0 Malignant neoplasm of skin of lip Malignant neoplasm of basal cell carcinoma of lip Excludes1: malignant neoplasm of lip (C00.-) C44.1 Malignant neoplasm of skin of eyelid, including canthus Excludes1: connective tissue of eyelid (C49.0) C44.10 Malignant neoplasm of skin of eyelid, including canthus, unspecified side C44.11 Malignant neoplasm of skin of right eyelid, including canthus C44.12 Malignant neoplasm of skin of left eyelid, including canthus C44.2 Malignant neoplasm of skin of ear and external auricular canal Excludes1: connective tissue of ear (C49.0) C44.20 Malignant neoplasm of skin of ear and external auricular canal, unspecified side C44.21 Malignant neoplasm of skin of right ear and external auricular canal C44.22 Malignant neoplasm of skin of left ear and external auricular canal C44.3 Malignant neoplasm of skin of other and unspecified parts of face C44.30 Malignant neoplasm of skin of unspecified part of face C44.31 Malignant neoplasm of skin of nose C44.39 Malignant neoplasm of skin of other parts of face C44.4 Malignant neoplasm of skin of scalp and neck C44.5 Malignant neoplasm of skin of trunk Excludes1: anus NOS (C21.0) scrotum (C63.2) C44.51 Malignant neoplasm of anal skin Malignant neoplasm of anal margin Malignant neoplasm of perianal skin C44.52 Malignant neoplasm of skin of breast C44.59 Malignant neoplasm of other part of trunk C44.6 Malignant neoplasm of skin of upper limb, including shoulder C44.60 Malignant neoplasm of skin of upper limb, including shoulder, unspecified side C44.61 Malignant neoplasm of skin of right upper limb, including shoulder C44.62 Malignant neoplasm of skin of left upper limb, including shoulder

21 C44.7 Malignant neoplasm of skin of lower limb, including hip C44.70 Malignant neoplasm of skin of lower limb, including hip, unspecified side C44.71 Malignant neoplasm of skin of right lower limb, including hip C44.72 Malignant neoplasm of skin of left lower limb, including hip C44.8 Malignant neoplasm of overlapping sites of skin C44.9 Malignant neoplasm of skin, unspecified Malignant neoplasms of mesothelial and soft tissue (C45-49) C45 Mesothelioma Use additional morphology code M905 with behavior code /3 C45.0 Mesothelioma of pleura Excludes1: other malignant neoplasm of pleura (C38.4) C45.1 Mesothelioma of peritoneum Mesothelioma of cul-de-sac Mesothelioma of mesentery Mesothelioma of mesocolon Mesothelioma of omentum Mesothelioma of peritoneum (parietal) (pelvic) Excludes1: other malignant neoplasm of soft tissue of peritoneum (C48.-) C45.2 Mesothelioma of pericardium Excludes1: other malignant neoplasm of pericardium (C38.0) C45.7 Mesothelioma of other sites C45.9 Mesothelioma, unspecified C46 Kaposi's sarcoma Use additional morphology code M9140 with behavior code /3 Code first any human immunodeficiency virus [HIV] disease (B20) C46.0 Kaposi's sarcoma of skin C46.1 Kaposi's sarcoma of soft tissue Kaposi's sarcoma of blood vessel Kaposi's sarcoma of connective tissue Kaposi's sarcoma of fascia Kaposi's sarcoma of ligament Kaposi's sarcoma of lymphatic(s) NEC Kaposi's sarcoma of muscle Excludes2: Kaposi's sarcoma of lymph glands and nodes (C46.3) C46.2 Kaposi's sarcoma of palate C46.3 Kaposi's sarcoma of lymph nodes C46.4 Kaposi's sarcoma of gastrointestinal sites C46.5 Kaposi's sarcoma of lung C46.50 Kaposi's sarcoma of lung, unspecified side C46.51 Kaposi's sarcoma of right lung C46.52 Kaposi's sarcoma of left lung C46.7 Kaposi's sarcoma of other sites

22 C46.9 Kaposi's sarcoma, unspecified C47 Malignant neoplasm of peripheral nerves and autonomic nervous system Includes: malignant neoplasm of sympathetic and parasympathetic nerves and ganglia Excludes1: Kaposi's sarcoma of soft tissue (C46.1) C47.0 Malignant neoplasm of peripheral nerves of head, face and neck Excludes1: malignant neoplasm of peripheral nerves of orbit (C69.6-) C47.1 Malignant neoplasm of peripheral nerves of upper limb, including shoulder C47.10 Malignant neoplasm of peripheral nerves of upper limb, including shoulder, unspecified side C47.11 Malignant neoplasm of peripheral nerves of right upper limb, including shoulder C47.12 Malignant neoplasm of peripheral nerves of left upper limb, including shoulder C47.2 Malignant neoplasm of peripheral nerves of lower limb, including hip C47.20 Malignant neoplasm of peripheral nerves of lower limb, including hip, unspecified side C47.21 Malignant neoplasm of peripheral nerves of right lower limb, including hip C47.22 Malignant neoplasm of peripheral nerves of left lower limb, including hip C47.3 Malignant neoplasm of peripheral nerves of thorax C47.4 Malignant neoplasm of peripheral nerves of abdomen C47.5 Malignant neoplasm of peripheral nerves of pelvis C47.6 Malignant neoplasm of peripheral nerves of trunk, unspecified C47.8 Malignant neoplasm of overlapping sites of peripheral nerves and autonomic nervous system C47.9 Malignant neoplasm of peripheral nerves and autonomic nervous system, unspecified C48 Malignant neoplasm of retroperitoneum and peritoneum Excludes1: Kaposi's sarcoma of connective tissue (C46.1) mesothelioma (C45.-) C48.0 Malignant neoplasm of retroperitoneum C48.1 Malignant neoplasm of specified parts of peritoneum Malignant neoplasm of cul-de-sac Malignant neoplasm of mesentery Malignant neoplasm of mesocolon Malignant neoplasm of omentum Malignant neoplasm of parietal peritoneum Malignant neoplasm of pelvic peritoneum

23 C48.2 Malignant neoplasm of peritoneum, unspecified C48.8 Malignant neoplasm of overlapping sites of retroperitoneum and peritoneum C49 Malignant neoplasm of other connective and soft tissue Includes: malignant neoplasm of blood vessel malignant neoplasm of bursa malignant neoplasm of cartilage malignant neoplasm of fascia malignant neoplasm of fat malignant neoplasm of ligament, except uterine malignant neoplasm of lymphatic vessel malignant neoplasm of muscle malignant neoplasm of synovia malignant neoplasm of tendon (sheath) malignant stromal tumors Excludes1: malignant neoplasm of cartilage (of): articular (C40-C41) larynx (C32.3) nose (C30.0) malignant neoplasm of connective tissue of internal organs (except stromal tumors)-code to malignant neoplasm of the site Excludes2: Kaposi's sarcoma of soft tissue (C46.1) malignant neoplasm of heart (C38.0) malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-) malignant neoplasm of peritoneum (C48.2) malignant neoplasm of retroperitoneum (C48.0) malignant neoplasm of uterine ligament (C57.3) mesothelioma (C45.-) C49.0 Malignant neoplasm of connective and soft tissue of head, face and neck Malignant neoplasm of connective tissue of ear Malignant neoplasm of connective tissue of eyelid Excludes1: connective tissue of orbit (C69.6-) C49.1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder C49.10 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder, unspecified side C49.11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder C49.12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder C49.2 Malignant neoplasm of connective and soft tissue of lower limb, including hip C49.20 Malignant neoplasm of connective and soft tissue of lower limb, including hip, unspecified side C49.21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip

24 C49.22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip C49.3 Malignant neoplasm of connective and soft tissue of thorax Malignant neoplasm of axilla Malignant neoplasm of diaphragm Malignant neoplasm of great vessels Excludes1: malignant neoplasm of breast (C50.-) malignant neoplasm of heart (C38.0) malignant neoplasm of mediastinum (C38.1-C38.3) malignant neoplasm of thymus (C37) C49.4 Malignant neoplasm of connective and soft tissue of abdomen Malignant neoplasm of abdominal wall Malignant neoplasm of hypochondrium C49.5 Malignant neoplasm of connective and soft tissue of pelvis Malignant neoplasm of buttock Malignant neoplasm of groin Malignant neoplasm of perineum C49.6 Malignant neoplasm of connective and soft tissue of trunk, unspecified Malignant neoplasm of back NOS C49.8 Malignant neoplasm of overlapping sites of connective and soft tissue Primary malignant neoplasm of two or more contiguous sites of connective and soft tissue C49.9 Malignant neoplasm of connective and soft tissue, unspecified Malignant neoplasm of breast(c50) C50 Malignant neoplasm of breast Includes: connective tissue of breast Paget's disease of breast Paget's disease of nipple Use additional code to identify estrogen receptor status (Z17.0, Z17.1) Excludes1: skin of breast (C43.5, C44.5) C50.0 Malignant neoplasm of nipple and areola C50.01 Malignant neoplasm of nipple and areola, female C Malignant neoplasm of nipple and areola, right female breast C Malignant neoplasm of nipple and areola, left female breast C Malignant neoplasm of nipple and areola, unspecified female breast C50.02 Malignant neoplasm of nipple and areola, male

25 C Malignant neoplasm of nipple and areola, right male breast C Malignant neoplasm of nipple and areola, left male breast C Malignant neoplasm of nipple and areola, unspecified male breast C50.1 Malignant neoplasm of central portion of breast C50.11 Malignant neoplasm of central portion of breast, female C Malignant neoplasm of central portion of right female breast C Malignant neoplasm of central portion of left female breast C Malignant neoplasm of central portion of unspecified female breast C50.12 Malignant neoplasm of central portion of breast, male C Malignant neoplasm of central portion of right male breast C Malignant neoplasm of central portion of left male breast C Malignant neoplasm of central portion of unspecified male breast C50.2 Malignant neoplasm of upper-inner quadrant of breast C50.21 Malignant neoplasm of upper-inner quadrant of breast, female C Malignant neoplasm of upper-inner quadrant of right female breast C Malignant neoplasm of upper-inner quadrant of left female breast C Malignant neoplasm of upper-inner quadrant of unspecified female breast C50.22 Malignant neoplasm of upper-inner quadrant of breast, male C Malignant neoplasm of upper-inner quadrant of right male breast C Malignant neoplasm of upper-inner quadrant of left male breast C Malignant neoplasm of upper-inner quadrant of unspecified male breast C50.3 Malignant neoplasm of lower-inner quadrant of breast C50.31 Malignant neoplasm of lower-inner quadrant of breast, female C Malignant neoplasm of lower-inner quadrant of right female breast C Malignant neoplasm of lower-inner quadrant of left female breast C Malignant neoplasm of lower-inner quadrant of unspecified female breast

26 C50.32 Malignant neoplasm of lower-inner quadrant of breast, male C Malignant neoplasm of lower-inner quadrant of right male breast C Malignant neoplasm of lower-inner quadrant of left male breast C Malignant neoplasm of lower-inner quadrant of unspecified male breast C50.4 Malignant neoplasm of upper-outer quadrant of breast C50.41 Malignant neoplasm of upper-outer quadrant of breast, female C Malignant neoplasm of upper-outer quadrant of right female breast C Malignant neoplasm of upper-outer quadrant of left female breast C Malignant neoplasm of upper-outer quadrant of unspecified female breast C50.42 Malignant neoplasm of upper-outer quadrant of breast, male C Malignant neoplasm of upper-outer quadrant of right male breast C Malignant neoplasm of upper-outer quadrant of left male breast C Malignant neoplasm of upper-outer quadrant of unspecified male breast C50.5 Malignant neoplasm of lower-outer quadrant of breast C50.51 Malignant neoplasm of lower-outer quadrant of breast, female C Malignant neoplasm of lower-outer quadrant of right female breast C Malignant neoplasm of lower-outer quadrant of left female breast C Malignant neoplasm of lower-outer quadrant of unspecified female breast C50.52 Malignant neoplasm of lower-outer quadrant of breast, male C Malignant neoplasm of lower-outer quadrant of right male breast C Malignant neoplasm of lower-outer quadrant of left male breast C Malignant neoplasm of lower-outer quadrant of unspecified male breast C50.6 Malignant neoplasm of axillary tail of breast C50.61 Malignant neoplasm of axillary tail of breast, female

27 C Malignant neoplasm of axillary tail of right female breast C Malignant neoplasm of axillary tail of left female breast C Malignant neoplasm of axillary tail of unspecified female breast C50.62 Malignant neoplasm of axillary tail of breast, male C Malignant neoplasm of axillary tail of right male breast C Malignant neoplasm of axillary tail of left male breast C Malignant neoplasm of axillary tail of unspecified male breast C50.8 Malignant neoplasm of overlapping sites of breast C50.81 Malignant neoplasm of overlapping sites of breast, female C Malignant neoplasm of overlapping sites of right female breast C Malignant neoplasm of overlapping sites of left female breast C Malignant neoplasm of overlapping sites of unspecified female breast C50.82 Malignant neoplasm of overlapping sites of breast, male C Malignant neoplasm of overlapping sites of right male breast C Malignant neoplasm of overlapping sites of left male breast C Malignant neoplasm of overlapping sites of unspecified male breast C50.9 Malignant neoplasm of breast of unspecified Site C50.91 Malignant neoplasm of breast of unspecified site, female C Malignant neoplasm of unspecifiedsite of right female breast C Malignant neoplasm of unspecified site of left female breast C Malignant neoplasm of unspecified site of unspecified female breast C50.92 Malignant neoplasm of breast of unspecified site, male C Malignant neoplasm of unspecified site of right male breast C Malignant neoplasm of unspecified site of left male breast C Malignant neoplasm of unspecified site of unspecified male breast Malignant neoplasm of female genital organs (C51-C58) Includes: malignant neoplasm of skin of female genital organs C51 Malignant neoplasm of vulva Excludes1: carcinoma in situ of vulva (D07.1) C51.0 Malignant neoplasm of labium majus Malignant neoplasm of Bartholin's [greater vestibular] gland C51.1 Malignant neoplasm of labium minus

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