Pediatric CNS Tumors. Disclosures. Acknowledgements. Introduction. Introduction. Posterior Fossa Tumors. Whitney Finke, MD

Size: px
Start display at page:

Download "Pediatric CNS Tumors. Disclosures. Acknowledgements. Introduction. Introduction. Posterior Fossa Tumors. Whitney Finke, MD"

Transcription

1 Pediatric CNS Tumors Disclosures Whitney Finke, MD Neuroradiology Fellow PGY-6 University of Utah Health Sciences Center Salt Lake City, Utah None Acknowledgements Introduction Nicholas A. Koontz, MD Luke Linscott, MD Tumor location guides your differential diagnosis: Posterior Fossa Sella/Suprasella Supratentorial Intraventricular Temporal Lobe Introduction Tumor location guides your differential diagnosis: Posterior Fossa Sella/Suprasella Supratentorial Intraventricular Temporal Lobe Posterior Fossa Tumors

2 Case 1 Case 1 7 year old female with progressive ataxia Sagittal T2WI Axial DWI Axial T1WI+C Case 1: Differential Diagnosis Case 1: Differential Diagnosis Atypical teratoid/rhabdoid tumor (AT/RT) Axial DWI Cystic mass with enhancing nodule Arise in cerebellar hemisphere CT: 20% Ca++ MRI: cyst does not FLAIR suppress, DWI negative, solid component +C Coronal T1WI+C Case 1: Differential Diagnosis Case 1: Differential Diagnosis : Midline, round 4 th ventricular mass 0-10 years CT: hyperdense, 20% calcify (Ca++), hemorrhage rare MRI: DWI hyperintense, variable +C 33% CSF spread : Midline, round 4 th ventricular mass 0-10 years CT: hyperdense, 20% calcify (Ca++), hemorrhage rare MRI: DWI hyperintense, variable +C 33% CSF spread Sagittal T1WI+C FS

3 Case 1: Differential Diagnosis Case 1: Differential Diagnosis Midline, 4 th ventricular tumors Soft/plastic CT: 50% Ca++, +/-cysts and hemorrhage MRI: DWI variable, +C variable Much less likely to disseminate Occur in younger children (0-3 years), peaks at 1 year Similar to medulloblastomas Cysts and hemorrhage are common, may Ca++ CSF spread Axial DWI Case 1: 7 year old female with progressive ataxia Case 1: Differential Diagnosis Sagittal T2WI Axial DWI Axial T1WI+C Axial DWI Companion Case 1.1 Companion Case year old female with lethargy

4 Companion Case 1.1 Companion Case 1.1 desmoplastic histologic variant Axial ADC Axial T1WI+C Medulloblastomas: WHO Updates Integrated histologic and genetic parameters Histologic: desmoplastic/nodular, extensive nodularity, large cell, anaplastic Genetic: WNTactivated, SHH activated, group 3, group 4 Louis, D.N., Perry, A., Reifenberger, G. et al. Acta Neuropathol (2016) 131: 803. doi: /s Case 2 Case 2 13 year old with headaches and vomiting

5 Case 2 Case 2: Differential Diagnosis Axial DWI Axial T1WI+C Axial T1WI+C Case 2: Differential Diagnosis Case 2: Pilocytic Axial T1WI+C Cystic mass with enhancing mural nodule Arises from the cerebellum and causes mass effect on the 4 th ventricle Most common posterior fossa tumor in 5-19 year olds Axial T1WI+C Case 3 Case 3 3 year old female with headaches and emesis Axial GRE Axial ADC Axial T1WI+C

6 Case 3: Differential Diagnosis Case 3 : Differential Diagnosis Case 3: Ependymoma Case 4 Plastic, 4 th ventricular tumor 3 rd most common posterior fossa tumor Bimodal: young children and teens/young adults 4 month old with increased head circumference and fussiness Case 4 Case 4 Axial ADC Axial T1WI+C

7 Case 4: Differential Diagnosis Case 4: Differential Diagnosis Case 4: AT/RT Case 4: AT/RT WHO Updates <2 % of all pediatric CNS tumors Imaging similar to medulloblastomas Usually off midline Cysts and hemorrhage are common <3 years, peak 1 year Must have alterations of INI1 or rarely BRG1 CNS embyronal tumor with rhabdoid features: histologic features without genetic alterations Case 5 Case 5 9 year old male with new onset strabismus Axial DWI Axial T1WI+C

8 Case 5: Differential Diagnosis Case 5: Differential Diagnosis Diffuse intrinsic pontine glioma (DIPG) Acute Disseminated Encephalomyelitis Osmotic Demyelination Syndrome Neurofibromatosis Type 1 FASI lesions Diffuse intrinsic pontine glioma (DIPG) Acute Disseminated Encephalomyelitis Osmotic Demyelination Syndrome Neurofibromatosis Type 1 FASI lesions Case 5: DIPG Case 5: DIPG WHO Updates 20-30% of pediatric posterior fossa tumors Expansile pontine mass engulfing the basilar flow void Grades II-IV CT: +/- necrosis, focal areas +C MRI: T2/FLAIR hyperintense, DWI negative, +C variable New Name: Diffuse midline glioma 80% H3 K27Mmutation WHO Grade IV Universally poor prognosis Pediatric Posterior Fossa Tumors Sellar and Suprasellar Pediatric Tumors Diffuse midline gliomas (formerly DIPG)

9 Case 6 Case 6 9 year old female with a bitemporal visual field defect Case 6 Case 6: Differential Diagnosis /Pilomyxoid Axial T1WI Axial T1WI+C Case 6: Differential Diagnosis Case 6: Differential Diagnosis 50% suprasellar tumors Usually adamantinomatous CT: Complex, cystic mass with Ca++ MRI: T1 hyperintense, T2 variable, FLAIR hyperintense, +C nodular or peripheral Sagittal T1WI+C 90% rule: 90% calcify 90% cystic 90% enhance 90% adamantinomatous Sagittal T1WI+C

10 Case 6: Differential Diagnosis Case 6: Differential Diagnosis Rare in pediatric patients (1.2%) Can be indistinguishable from craniopharyngiomas Nonenhancing Noncalcified Sagittal T1WI Pituitary Macroadenoma Expansile pituitary mass CT: may have cysts, necrosis, hemorrhage MRI: isointense to gray matter with homogeneous +C Rare in children Sagittal T1WI+C Case 6: Differential Diagnosis Case 6: Differential Diagnosis CT: hyperdense, Ca++ and hemorrhage rare MRI: DWI hyperintense, marked +C 5-10% have additional lesion in pineal region CSF spread common Sagittal T1WI+C /Pilomyxoid Chiasmatic/Hypothal amic or optic pathway glioma Less common location than PF Fusiform optic nerve enlargement vs. rounded cystic mass MRI: FLAIR hyperintense, +C variable Axial FLAIR Case 6: 9 year old female with a bitemporal visual field defect Case 6: 9 year old female with a bitemporal visual field defect /Pilomyxoid /Pilomyxoid

11 Case 7 Case 7 14 year old male with vision loss Case 7 Case 7 /Pilomyxoid Axial ADC Axial T1WI+C Case 7 Case 7: Germinoma /Pilomyxoid Hyperdense on CT and +DWI years M>F, except in sella/suprasellar region Incidence varies based on location: 1-3% in western countries, 11% in Japan

12 Case 8 Case 8 13 year old female with vision loss Sagittal T2WI Axial FLAIR Axial T1WI+C Case 8 Case 8 /Pilomyxoid /Pilomyxoid Sagittal T2WI Sagittal T2WI Case 8: Pilomyxoid Pediatric Sella/Suprasella Tumors Appearance varies with NF vs. sporadic FLAIR hyperintense, +C variable WHO updates: Not automatically Grade II Overlap with pilocytic, can mature to a Grade I Sagittal T2WI /Pilomyxoid s

13 Conclusion Tumor location guides your differential diagnosis: Posterior Fossa Sella/Suprasella Supratentorial Intraventricular Temporal Lobe Pediatric CNS Tumors Whitney Finke, MD Department of Radiology University of Utah Health Sciences Center Salt Lake City, Utah

Metastasis. 57 year old with progressive Headache and Right Sided Visual Loss

Metastasis. 57 year old with progressive Headache and Right Sided Visual Loss Metastasis 1% of sellar/parasellar masses Usually occurs with known primary Can involve third ventricle, hypothalamus, infundibular stalk May be both supra-, intrasellar 57 year old with progressive Headache

More information

Posterior fossa tumors: clues to differential diagnosis with case-based review

Posterior fossa tumors: clues to differential diagnosis with case-based review Posterior fossa tumors: clues to differential diagnosis with case-based review Poster No.: C-0323 Congress: ECR 2017 Type: Educational Exhibit Authors: H. A. Aboughalia, M. Abdelhady; Doha/QA Keywords:

More information

Supra- and infratentorial brain tumors from childhood to maternity

Supra- and infratentorial brain tumors from childhood to maternity Supra- and infratentorial brain tumors from childhood to maternity What to expect? I am going to show you the characteristic imaging findings of following tumors: Thierry A.G.M. Huisman, MD, FICIS, EQNR

More information

Pediatric Brain Tumors: Updates in Treatment and Care

Pediatric Brain Tumors: Updates in Treatment and Care Pediatric Brain Tumors: Updates in Treatment and Care Writer Classroom Rishi R. Lulla, MD MS Objectives Introduce the common pediatric brain tumors Discuss current treatment strategies for pediatric brain

More information

Case Studies in Sella/Parasellar Region. Child thirsty, increased urination. Imaging. Suprasellar Germ Cell Tumor (Germinoma) No Disclosures

Case Studies in Sella/Parasellar Region. Child thirsty, increased urination. Imaging. Suprasellar Germ Cell Tumor (Germinoma) No Disclosures Case Studies in Sella/Parasellar Region No Disclosures 2018 Head and Neck Imaging Conference Child thirsty, increased urination Suprasellar Germ Cell Tumor (Germinoma) Midline Pineal >> Suprasellar > Other

More information

CT & MRI Evaluation of Brain Tumour & Tumour like Conditions

CT & MRI Evaluation of Brain Tumour & Tumour like Conditions CT & MRI Evaluation of Brain Tumour & Tumour like Conditions Dr. Anjana Trivedi 1, Dr. Jay Thakkar 2, Dr. Maulik Jethva 3, Dr. Ishita Virda 4 1 M.D. Radiology, Professor and Head, P.D.U. Medical College

More information

Cross sectional imaging of Intracranial cystic lesions Abdel Razek A

Cross sectional imaging of Intracranial cystic lesions Abdel Razek A Cross sectional imaging of Intracranial cystic lesions Abdel Razek A Department of Radiology. Mansoura Faculty of Medicine, Mansoura. Egypt. arazek@mans.edu.eg Introduction Intracranial cystic lesions

More information

Brain Tumors. Medulloblastoma. Pilocytic astrocytoma: Ahmed Koriesh, MD. Pathological finding

Brain Tumors. Medulloblastoma. Pilocytic astrocytoma: Ahmed Koriesh, MD. Pathological finding NeuroPathology Page 8 Brain Tumors Pathological finding Pseudorosette Rosenthal fibers Rosettes Wet Keratin Psammoma bodies Fried egg Tumor Ependymoma, SEGA Pilocytic astrocytoma Medulloblastoma Craniopharyngioma

More information

CNS TUMORS. D r. Ali Eltayb ( U. of Omdurman. I ). M. Path (U. of Alexandria)

CNS TUMORS. D r. Ali Eltayb ( U. of Omdurman. I ). M. Path (U. of Alexandria) CNS TUMORS D r. Ali Eltayb ( U. of Omdurman. I ). M. Path (U. of Alexandria) CNS TUMORS The annual incidence of intracranial tumors of the CNS ISmore than intraspinal tumors May be Primary or Secondary

More information

Joana Ramalho, MD C. Ryan Miller, MD, PhD

Joana Ramalho, MD C. Ryan Miller, MD, PhD Joana Ramalho, MD C. Ryan Miller, MD, PhD Case 1 3 month old baby girl Presented with new onset of seizures Newborn. Questionable blurring of the gray-white junction within the right occipital lobe. Findings

More information

Peter Canoll MD. PhD.

Peter Canoll MD. PhD. Tumors of the Nervous System Peter Canoll MD. PhD. What I want to cover What are the most common types of brain tumors? Who gets them? How do they ypresent? What do they look like? How do they behave?

More information

Tumors of the Nervous System

Tumors of the Nervous System Tumors of the Nervous System Peter Canoll MD. PhD. What I want to cover What are the most common types of brain tumors? Who gets them? How do they present? What do they look like? How do they behave? 1

More information

Unknown Cases. Financial Disclosures & Disclaimers. Unknown Cases Case #2. Unknown Cases Case #1. Differentials in Pediatric Brain Imaging

Unknown Cases. Financial Disclosures & Disclaimers. Unknown Cases Case #2. Unknown Cases Case #1. Differentials in Pediatric Brain Imaging Financial Disclosures & Disclaimers Differentials in Pediatric Brain Imaging William T. O Brien, Sr., D.O. Program Director, Diagnostic Radiology Residency, DGMC Associate Clinical Professor of Radiology

More information

SWI including phase and magnitude images

SWI including phase and magnitude images On-line Table: MRI imaging recommendation and summary of key features Sequence Pathologies Visible Key Features T1 volumetric high-resolution whole-brain reformatted in axial, coronal, and sagittal planes

More information

NEURORADIOLOGY-NEUROPATHOLOGY CONFERENCE

NEURORADIOLOGY-NEUROPATHOLOGY CONFERENCE THE UNIVERSITY OF NORTH CAROLINA at CHAPEL HILL SEPTEMBER 2013 NEURORADIOLOGY-NEUROPATHOLOGY CONFERENCE Claudia da Costa Leite, MD, PhD Thomas Bouldin, MD CASE 1 6 y-o female with headaches and vomiting

More information

PITUITARY PARASELLAR LESIONS. Kim Learned, MD

PITUITARY PARASELLAR LESIONS. Kim Learned, MD PITUITARY PARASELLAR LESIONS Kim Learned, MD DIFFERENTIALS Pituitary Sella Clivus, Sphenoid Sinus Suprasellar Optic chiasm, Hypothalamus, Circle of Willis Parasellar Cavernous Sinus Case 1 17 YEAR-OLD

More information

Laurie A. Loevner, MD

Laurie A. Loevner, MD Laurie A. Loevner, MD Chief, Division of Neuroradiology UPHS Professor of Radiology, Otorhinolaryngology: Head & Neck Surgery, Neurosurgery, and Ophthalmology University of Pennsylvania Health System Disclosures

More information

Diffusion-weighted imaging and ADC mapping in the differentiation of intraventricular brain tumors

Diffusion-weighted imaging and ADC mapping in the differentiation of intraventricular brain tumors Diffusion-weighted imaging and ADC mapping in the differentiation of intraventricular brain tumors Poster No.: C-2652 Congress: ECR 2010 Type: Educational Exhibit Topic: Neuro Authors: M. Gavrilov, T.

More information

Case Studies in the Skull Base

Case Studies in the Skull Base Case Studies in the Skull Base Amy C Tsai, MD Neuroradiology Fellow Department of Radiology and Imaging Sciences University of Utah Health Sciences Center Salt Lake City, Utah, USA No disclosures related

More information

Year 2003 Paper two: Questions supplied by Tricia

Year 2003 Paper two: Questions supplied by Tricia question 43 A 42-year-old man presents with a two-year history of increasing right facial numbness. He has a history of intermittent unsteadiness, mild hearing loss and vertigo but has otherwise been well.

More information

EXPERT DIFFERENTIAL DIAGNOSIS:

EXPERT DIFFERENTIAL DIAGNOSIS: EXPERT DIFFERENTIAL DIAGNOSIS: Sellar Region Anne G. Osborn, M.D. DISCLOSURE: Published RSNA 2008 SELLA, PITUITARY: Normal Gross, 3T Anatomy SELLA, PITUITARY: Anatomically-Based Differential Diagnoses

More information

Adult Brain Tumours: an approach based on imaging findings

Adult Brain Tumours: an approach based on imaging findings Adult Brain Tumours: an approach based on imaging findings Robert J Sevick, MD, FRCPC, FACR Professor, Radiology and Clinical Neurosciences Cumming School of Medicine University of Calgary Learning objectives:

More information

DISCLOSURES LEARNING OBJECTIVES WE WILL NOT DISCUSS. CSB: Birdseye View MESSAGE NAVIGATING THE SELLA AND CENTRAL SKULL BASE

DISCLOSURES LEARNING OBJECTIVES WE WILL NOT DISCUSS. CSB: Birdseye View MESSAGE NAVIGATING THE SELLA AND CENTRAL SKULL BASE NAVIGATING THE SELLA AND CENTRAL SKULL BASE Christopher P. Hess, M.D., Ph.D. DISCLOSURES Research Support, General Electric SLIDES: http://www.radiology.ucsf.edu/research/meetings/rsna LEARNING OBJECTIVES

More information

Disclosure. + Outline. Case-based approach to neurological emergencies that might present to the ED

Disclosure. + Outline. Case-based approach to neurological emergencies that might present to the ED Kathleen R. Fink, MD University of Washington 5 th Nordic Emergency Radiology Course May 21, 2015 Disclosure My spouse receives research salary support from: Bracco BayerHealthcare Guerbet Outline Case-based

More information

NEURO IMAGING OF ACUTE STROKE

NEURO IMAGING OF ACUTE STROKE 1 1 NEURO IMAGING OF ACUTE STROKE ALICIA RICHARDSON, MSN, RN, ACCNS-AG, ANVP-BC WENDY SMITH, MA, RN, MBA, SCRN, FAHA LYNN HUNDLEY, APRN, CNRN, CCNS, ANVP-BC 2 2 1 DISCLOSURES Alicia Richardson: Stryker

More information

BRAIN STEM AND CEREBELLUM..

BRAIN STEM AND CEREBELLUM.. Lecture Title: BRAIN STEM AND CEREBELLUM.. (CNS Block, Radiology) Dr. Hamdy Hassan Ass.Prof. Consultant Radiology Department KKHU King Saud University Lecture Objectives.. Students at the end of the lecture

More information

MRI OF THE THALAMUS. Mohammed J. Zafar, MD, FAAN Kalamazoo, MI

MRI OF THE THALAMUS. Mohammed J. Zafar, MD, FAAN Kalamazoo, MI 1 MRI OF THE THALAMUS Mohammed J. Zafar, MD, FAAN Kalamazoo, MI Objectives: The thalamic nuclei can be involved in a wide variety of conditions. A systematic imaging approach would be useful for narrowing

More information

Role of Diffusion Mri In Differentiation Between The Common Pediatric Posterior Fossa Brain Tumors.

Role of Diffusion Mri In Differentiation Between The Common Pediatric Posterior Fossa Brain Tumors. The Egyptian Journal of Hospital Medicine (July 2018) Vol. 73 (2), Page 6090-6096 Role of Diffusion Mri In Differentiation Between The Common Pediatric Posterior Fossa Brain Tumors. HanaaAbdelkader Ahmed

More information

Part II - Revising the sellar and parasellar region: differential diagnosis of a sellar region mass

Part II - Revising the sellar and parasellar region: differential diagnosis of a sellar region mass Part II - Revising the sellar and parasellar region: differential diagnosis of a sellar region mass Poster No.: C-1390 Congress: ECR 2015 Type: Educational Exhibit Authors: I. Candelaria, C. Figueira,

More information

Case 7391 Intraventricular Lesion

Case 7391 Intraventricular Lesion Case 7391 Intraventricular Lesion Bastos Lima P1, Marques C1, Cabrita F2, Barbosa M2, Rebelo O3, Rio F1. 1Neuroradiology, 2Neurosurgery, 3Neuropathology, Coimbra University Hospitals, Portugal. University

More information

Masses of the Corpus Callosum

Masses of the Corpus Callosum Masses of the Corpus Callosum Kesav Raghavan, HMS Year III Dr. Agenda Corpus Callosum Development and Anatomy Our Patient: Clinical Presentation Differential Diagnosis of Masses in the Corpus Callosum

More information

Hypothalamic glioma masquerading as craniopharyngioma

Hypothalamic glioma masquerading as craniopharyngioma 1 di 7 24/01/2014 18.58 J Neurosci Rural Pract. 2013 Jul-Sep; 4(3): 323 325. doi: 10.4103/0976-3147.118790 PMCID: PMC3821425 Hypothalamic glioma masquerading as craniopharyngioma Sameer Vyas, Nidhi Prabhakar,

More information

Imaging The Turkish Saddle. Russell Goodman, HMS III Dr. Gillian Lieberman

Imaging The Turkish Saddle. Russell Goodman, HMS III Dr. Gillian Lieberman Imaging The Turkish Saddle Russell Goodman, HMS III Dr. Gillian Lieberman Learning Objectives Review the anatomy of the sellar region Discuss the differential diagnosis of sellar masses Discuss typical

More information

Role of Diffusion weighted Imaging in the Evaluation of Intracranial Tumors

Role of Diffusion weighted Imaging in the Evaluation of Intracranial Tumors IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-issn: 2279-0853, p-issn: 2279-0861.Volume 15, Issue 12 Ver. IX (December. 2016), PP 99-104 www.iosrjournals.org Role of Diffusion weighted Imaging

More information

Neuropathology Evening Session: Case 3

Neuropathology Evening Session: Case 3 Neuropathology Evening Session: Case 3 Christine E. Fuller, MD Cincinnati Children s Hospital Medical Center Disclosure of Relevant Financial Relationships USCAP requires that all faculty in a position

More information

H Haloes cautions, 57 neurocytomas, perinuclear, 56 Headache blue cell tumors, 147 cautions, 135, 147, 152 clinical history, 132, 144, 148

H Haloes cautions, 57 neurocytomas, perinuclear, 56 Headache blue cell tumors, 147 cautions, 135, 147, 152 clinical history, 132, 144, 148 Index A ADC. See Apparent diffusion coefficient Adult. See also Supratentorial mass, adult cerebral tumor, 1 headache and ataxia cysts, mural nodules, 118 sporadic tumors, 118 headaches and visual changes,

More information

Structural and functional imaging for the characterization of CNS lymphomas

Structural and functional imaging for the characterization of CNS lymphomas Structural and functional imaging for the characterization of CNS lymphomas Cristina Besada Introduction A few decades ago, Primary Central Nervous System Lymphoma (PCNSL) was considered as an extremely

More information

Disclosures. Posterior Fossa Masses. I m from the Government. and I here to help! Differential Diagnosis

Disclosures. Posterior Fossa Masses. I m from the Government. and I here to help! Differential Diagnosis Posterior Fossa Masses Differential Diagnosis James G. Smirniotopoulos, M.D. Radiology, Neurology, Biomedical Informatics Uniformed Services University Bethesda, Maryland http://rad.usuhs.edu http://medpix.usuhs.edu

More information

Tumors of the Central Nervous System

Tumors of the Central Nervous System Tumors of the Central Nervous System 1 Financial Disclosures I have NO SIGNIFICANT FINANCIAL, GENERAL, OR OBLIGATION INTERESTS TO REPORT Introduction General: Brain tumors are lesions that have mass effect

More information

Complex Hydrocephalus

Complex Hydrocephalus 2012 Hydrocephalus Association Conference Washington, DC - June 27-July1, 2012 Complex Hydrocephalus Marion L. Walker, MD Professor of Neurosurgery & Pediatrics Primary Children s Medical Center University

More information

New Imaging Concepts in Central Nervous System Neoplasms

New Imaging Concepts in Central Nervous System Neoplasms New Imaging Concepts in Central Nervous System Neoplasms Maarten Lequin Department of Pediatric Radiology Wilhelmina Children s Hospital/University Medical Center Utrecht New Imaging Concepts in Central

More information

Conventional and Advanced MRI Features of Pediatric Intracranial Tumors: Posterior Fossa and Suprasellar Tumors

Conventional and Advanced MRI Features of Pediatric Intracranial Tumors: Posterior Fossa and Suprasellar Tumors Neuroradiology/Head and Neck Imaging Review Plaza et al. MRI of Posterior Fossa and Suprasellar Tumors Neuroradiology/Head and Neck Imaging Review Michael J. Plaza 1 Maria J. Borja 1 Nolan Altman 2 Gaurav

More information

Intracranial Ganglioglioma: MR, CT,

Intracranial Ganglioglioma: MR, CT, 109 Intracranial Ganglioglioma: MR, CT, and Clinical Findings in 18 Patients Mauricio Castillo 1 Patricia C. Davis 1 Yoshii Takei 2 James C. Hoffman, Jr. 1 Eighteen cases of pathologically proved intracranial

More information

MRI Findings Of An Atypical Cystic Meningioma A Rare Case

MRI Findings Of An Atypical Cystic Meningioma A Rare Case ISPUB.COM The Internet Journal of Radiology Volume 14 Number 1 MRI Findings Of An Atypical Cystic Meningioma A Rare Case D Saxena, P Rout, K Pavan, B Philip Citation D Saxena, P Rout, K Pavan, B Philip.

More information

MRI findings in childhood neurohypophyseal germinomas

MRI findings in childhood neurohypophyseal germinomas MRI findings in childhood neurohypophyseal germinomas Poster No.: C-1587 Congress: ECR 2015 Type: Scientific Exhibit Authors: C. Laganâ, S. I. Sirvent, M. A. Lopez-Pino, G. Albi, I. Solis Muniz, E. García

More information

Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ )

Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ ) 1 di 8 04/03/2017 07.31 NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute

More information

Intracranial arachnoid cysts: radiological study of the incidental, the symptomatic and the complicated.

Intracranial arachnoid cysts: radiological study of the incidental, the symptomatic and the complicated. Intracranial arachnoid cysts: radiological study of the incidental, the symptomatic and the complicated. Poster No.: C-1092 Congress: ECR 2015 Type: Educational Exhibit Authors: C. Ospina Moreno, I. Montejo

More information

Anaplastic Pilocytic Astrocytoma: The fusion of good and bad

Anaplastic Pilocytic Astrocytoma: The fusion of good and bad Anaplastic Pilocytic Astrocytoma: The fusion of good and bad Alexandrina Nikova 1, Charalampos-Chrysovalantis Chytoudis-Peroudis 2, Penelope Korkolopoulou 3 and Dimitrios Kanakis 4 Abstract 5 Pilocytic

More information

RINGS N THINGS: Imaging Patterns in Differential Diagnosis. Anne G. Osborn, M.D.

RINGS N THINGS: Imaging Patterns in Differential Diagnosis. Anne G. Osborn, M.D. RINGS N THINGS: Imaging Patterns in Differential Diagnosis Anne G. Osborn, M.D. ExpDDxs: Intra-axial (Parenchymal) Lesions Ring-enhancing lesions, solitary 1 Ring-enhancing lesion crossing corpus callosum

More information

Detection of Leptomeningeal CNS Metastases in Children

Detection of Leptomeningeal CNS Metastases in Children Detection of Leptomeningeal CNS Metastases in Children Noah D. Sabin, M.D. Julie H. Harreld M.D. Kathleen J. Helton M.D. Zoltan Patay M.D., Ph.D. St. Jude Children s Research Hospital Memphis, TN Leptomeningeal

More information

Differential diagnosis of intracranial cystic lesions.

Differential diagnosis of intracranial cystic lesions. Differential diagnosis of intracranial cystic lesions. Poster No.: C-0215 Congress: ECR 2015 Type: Educational Exhibit Authors: S. P. G. Alandete, M. A. Meseguer, E. De la Via, D. Uceda, C. Poyatos; Valencia/ES

More information

Pediatric Spine Tumors (and other masses)

Pediatric Spine Tumors (and other masses) Pediatric Spine Tumors (and other masses) Francisco A Perez, MD, PhD Assistant Professor Neuroradiology and Pediatric Radiology Seattle Children s Hospital University of Washington, Seattle Commercial

More information

CT - Brain Examination

CT - Brain Examination CT - Brain Examination Submitted by: Felemban 1 CT - Brain Examination The clinical indication of CT brain are: a) Chronic cases (e.g. headache - tumor - abscess) b) ER cases (e.g. trauma - RTA - child

More information

Case Studies in CPA/IAC

Case Studies in CPA/IAC Outline Case Studies in CPA/IAC Atul K Mallik MD PhD Department of Radiology and Imaging Sciences University of Utah Health Sciences Center Salt Lake City, Utah, USA Case based review of cerebellopontine

More information

CNS pathology Third year medical students. Dr Heyam Awad 2018 Lecture 12: CNS tumours 2/3

CNS pathology Third year medical students. Dr Heyam Awad 2018 Lecture 12: CNS tumours 2/3 CNS pathology Third year medical students Dr Heyam Awad 2018 Lecture 12: CNS tumours 2/3 Pilocytic astrocytoma Relatively benign ( WHO grade 1) Occurs in children and young adults Mostly: in the cerebellum

More information

General: Brain tumors are lesions that have mass effect distorting the normal tissue and often result in increased intracranial pressure.

General: Brain tumors are lesions that have mass effect distorting the normal tissue and often result in increased intracranial pressure. 1 Lecture Objectives Know the histologic features of the most common tumors of the CNS. Know the differences in behavior of the different tumor types. Be aware of the treatment modalities in the various

More information

ARRO Case: Diffuse Intrinsic Pontine Glioma

ARRO Case: Diffuse Intrinsic Pontine Glioma ARRO Case: Diffuse Intrinsic Pontine Glioma Nicholas DeNunzio, MD, PhD (PGY-3) Faculty Advisor: Louis S. Constine, MD, FASTRO Department of Radiation Oncology University of Rochester Case Presentation

More information

Case Report Cystic Meningioma Simulating Arachnoid Cyst: Report of an Unusual Case

Case Report Cystic Meningioma Simulating Arachnoid Cyst: Report of an Unusual Case Case Reports in Radiology, Article ID 371969, 4 pages http://dx.doi.org/10.1155/2014/371969 Case Report Cystic Meningioma Simulating Arachnoid Cyst: Report of an Unusual Case Docampo Jorge, 1 Gonzalez

More information

Update on Pediatric Brain Tumors

Update on Pediatric Brain Tumors Update on Pediatric Brain Tumors David I. Sandberg, M.D. Director of Pediatric Neurosurgery & Associate Professor Dr. Marnie Rose Professorship in Pediatric Neurosurgery Pre-talk Questions for Audience

More information

Non-Traumatic Neuro Emergencies

Non-Traumatic Neuro Emergencies Department of Radiology University of California San Diego Non-Traumatic Neuro Emergencies John R. Hesselink, M.D. Nontraumatic Neuroemergencies 1. Acute focal neurological deficit 2. Worst headache of

More information

WHO 2016 CNS Tumor Classification Update. DISCLOSURES (Arie Perry, MD) PATTERN RECOGNITION. Arie Perry, M.D. Director, Neuropathology

WHO 2016 CNS Tumor Classification Update. DISCLOSURES (Arie Perry, MD) PATTERN RECOGNITION. Arie Perry, M.D. Director, Neuropathology WHO 2016 CNS Tumor Classification Update Arie Perry, M.D. Director, Neuropathology DISCLOSURES (Arie Perry, MD) I have no financial relationships to disclose. - and - I will not discuss off label use or

More information

Case Report Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child

Case Report Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child Case Reports in Oncological Medicine Volume 2013, Article ID 815923, 4 pages http://dx.doi.org/10.1155/2013/815923 Case Report Atypical Presentation of Atypical Teratoid Rhabdoid Tumor in a Child Y. T.

More information

Benign brain lesions

Benign brain lesions Benign brain lesions Diagnostic and Interventional Radiology Hung-Wen Kao Department of Radiology, Tri-Service General Hospital, National Defense Medical Center Computed tomography Hounsfield unit (HU)

More information

Table of Contents: SKULL AND BRAIN. Scalp, Skull. Anatomically Based Differentials. Skull Normal Variants. Scalp Mass, Child.

Table of Contents: SKULL AND BRAIN. Scalp, Skull. Anatomically Based Differentials. Skull Normal Variants. Scalp Mass, Child. Table of Contents: SKULL AND BRAIN Scalp, Skull Skull Normal Variants Scalp Mass, Child Scalp Mass, Adult Congenital Anomalies of Skull Base Sellar/Parasellar Mass With Skull Base Invasion "Hair on End"

More information

Brainstem and Cerebellum

Brainstem and Cerebellum Brainstem and Cerebellum Lecture two Objectives: 1. Identify radiological anatomy of brain stem and cerebellum. 2. Compares CT and MRI imaging of brain stem and cerebellum. 3. Recognize the imaging findings

More information

Supratentorial brain tumors in the first year of life are challenging

Supratentorial brain tumors in the first year of life are challenging ORIGINAL RESEARCH PEDIATRICS Diffusion Imaging for Tumor Grading of Supratentorial Brain Tumors in the First Year of Life S.F. Kralik, A. Taha, A.P. Kamer, J.S. Cardinal, T.A. Seltman, and C.Y. Ho ABSTRACT

More information

S Alandete, M Meseguer, CR Poyatos, D Uceda, E de la Via, J Sales, J Vilar. H.U. Dr Peset, Valencia (Spain)

S Alandete, M Meseguer, CR Poyatos, D Uceda, E de la Via, J Sales, J Vilar. H.U. Dr Peset, Valencia (Spain) S Alandete, M Meseguer, CR Poyatos, D Uceda, E de la Via, J Sales, J Vilar. H.U. Dr Peset, Valencia (Spain) Introduction Cystic lesions are usually a common finding in clinical practice and you can find

More information

Brainstem diffuse gliomas: radiologic findings.

Brainstem diffuse gliomas: radiologic findings. Brainstem diffuse gliomas: radiologic findings. Poster No.: C-2220 Congress: ECR 2013 Type: Educational Exhibit Authors: E. GARCIA MARTINEZ 1, D. H. Jiménez 1, L. Navarro Vilar 2, C. P. Fernandez Ruiz

More information

Imaging Findings of CNS Atypical Teratoid/Rhabdoid Tumors

Imaging Findings of CNS Atypical Teratoid/Rhabdoid Tumors AJNR Am J Neuroradiol 25:476 480, March 2004 Case Report Imaging Findings of CNS Atypical Teratoid/Rhabdoid Tumors Atilla Arslanoglu, Nafi Aygun, Deapak Tekhtani, Leslie Aronson, Ken Cohen, Peter C. Burger,

More information

Understanding general brain tumor pathology, Part I: The basics. Craig Horbinski, M.D., Ph.D. Department of Pathology University of Kentucky

Understanding general brain tumor pathology, Part I: The basics. Craig Horbinski, M.D., Ph.D. Department of Pathology University of Kentucky Understanding general brain tumor pathology, Part I: The basics Craig Horbinski, M.D., Ph.D. Department of Pathology University of Kentucky plan of attack what IS a pathologist, anyway? what s so special

More information

Oligodendroglioma: imaging findings, radio-pathological correlation and evolution

Oligodendroglioma: imaging findings, radio-pathological correlation and evolution Oligodendroglioma: imaging findings, radio-pathological correlation and evolution Poster No.: C-2104 Congress: ECR 2013 Type: Authors: Keywords: DOI: Scientific Exhibit A. Hernandez Castro, M. D. Monedero

More information

Primary Central Nervous System Lymphoma with Lateral Ventricle Involvement

Primary Central Nervous System Lymphoma with Lateral Ventricle Involvement The Open Medical Imaging Journal, 2012, 6, 103-107 103 Open Access Primary Central Nervous System Lymphoma with Lateral Ventricle Involvement Yumi Oie 1,*, Kazuhiro Murayama 1, Shinya Nagahisa 2, Masato

More information

Case 1. Maysa Al-Hussaini MD FRCPath

Case 1. Maysa Al-Hussaini MD FRCPath Case 1 Maysa Al-Hussaini MD FRCPath MAYSA King AL-HUSSAINI Hussein Cancer MD Center MRCPATH KING HUSSEIN Amman CANCER Jordan CENTER Clinical history 4 year old boy History of frontal headache, sleepiness.

More information

Outline. Neuroradiology. Diffusion Imaging in. Clinical Applications of. Basics of Diffusion Imaging. Basics of Diffusion Imaging

Outline. Neuroradiology. Diffusion Imaging in. Clinical Applications of. Basics of Diffusion Imaging. Basics of Diffusion Imaging Clinical Applications of Diffusion Imaging in Neuroradiology No disclosures Stephen F. Kralik Assistant Professor of Radiology Indiana University School of Medicine Department of Radiology and Imaging

More information

Medulloblastoma with atypical dynamic imaging changes: A case report with literature review

Medulloblastoma with atypical dynamic imaging changes: A case report with literature review Accepted Manuscript Medulloblastoma with atypical dynamic imaging changes: A case report with literature review Shuang-Shuang Song, Jian-Hong Wang, Wei-Wei Fu, Ying Li, Qing-Lan Sui, Xue-Jun Liu PII: S1878-8750(17)30950-6

More information

Pathologic Analysis of CNS Surgical Specimens

Pathologic Analysis of CNS Surgical Specimens 2015 Kenneth M. Earle Memorial Neuropathology Review Pathologic Analysis of CNS Surgical Specimens Peter C. Burger, MD Interdisciplinary Quality Control Familiarity with entities Use of diagnostic algorithm

More information

Challenging Paediatric Brain Tumours. ASP Belfast March 2017 Dr Jane Pears Consultant Paediatric Oncologist, Dublin

Challenging Paediatric Brain Tumours. ASP Belfast March 2017 Dr Jane Pears Consultant Paediatric Oncologist, Dublin Challenging Paediatric Brain Tumours ASP Belfast March 2017 Dr Jane Pears Consultant Paediatric Oncologist, Dublin Overview (i) Paediatric malignancy (ii) Central nervous system tumours (iii) Diffuse Intrinsic

More information

NEUROIMAGING. July 2013, Vol. 2, Issue 3. Official Journal of the American Osteopathic College of Radiology. Editor: William T. O Brien, Sr., D.O.

NEUROIMAGING. July 2013, Vol. 2, Issue 3. Official Journal of the American Osteopathic College of Radiology. Editor: William T. O Brien, Sr., D.O. ISSN: 2165-3259 JAOCR Official Journal of the American Osteopathic College of Radiology NEUROIMAGING Editor: William T. O Brien, Sr., D.O. July 2013, Vol. 2, Issue 3 JAOCR About the Journal Aims and Scope

More information

Infratentorial and Intraparenchymal Subependymoma in the Cerebellum: Case Report

Infratentorial and Intraparenchymal Subependymoma in the Cerebellum: Case Report Case Report Neuroimaging and Head and Neck http://dx.doi.org/10.3348/kjr.2014.15.1.151 pissn 1229-6929 eissn 2005-8330 Korean J Radiol 2014;15(1):151-155 Infratentorial and Intraparenchymal Subependymoma

More information

STUDY OFPAEDIATRIC CNS TUMORS IN TERTIARY CARE CENTER

STUDY OFPAEDIATRIC CNS TUMORS IN TERTIARY CARE CENTER IJCRR Section: Healthcare Sci. Journal Impact Factor 4.016 Original Article STUDY OFPAEDIATRIC CNS TUMORS IN TERTIARY CARE CENTER Grishma P. Jobanputra Tutor, Department of Pathology, B.J. Medical College,

More information

WHO 2016 CNS TUMOR CLASSIFICATION UPDATE. Arie Perry, M.D. Director, Neuropathology

WHO 2016 CNS TUMOR CLASSIFICATION UPDATE. Arie Perry, M.D. Director, Neuropathology WHO 2016 CNS TUMOR CLASSIFICATION UPDATE Arie Perry, M.D. Director, Neuropathology DISCLOSURES (Arie Perry, MD) I have no financial relationships to disclose. - and - I will not discuss off label use or

More information

Childhood brain tumours

Childhood brain tumours Childhood brain tumours Our bodies are made up of billions of cells. Normally, these cells reproduce and repair themselves in a controlled way and do not cause us any problems. If for some reason this

More information

Where Has My Vision Gone? Evaluation of Sellar Lesions. Caleb Stowell,, HMS III Gillian Lieberman, MD November 2008

Where Has My Vision Gone? Evaluation of Sellar Lesions. Caleb Stowell,, HMS III Gillian Lieberman, MD November 2008 Where Has My Vision Gone? Evaluation of Sellar Lesions Caleb Stowell,, HMS III Gillian Lieberman, MD November 2008 Objectives Present a case highlighting the clinical presentation and evaluation of a sellar

More information

TABLES. Imaging Modalities Evidence Tables Table 1 Computed Tomography (CT) Imaging. Conclusions. Author (Year) Classification Process/Evid ence Class

TABLES. Imaging Modalities Evidence Tables Table 1 Computed Tomography (CT) Imaging. Conclusions. Author (Year) Classification Process/Evid ence Class TABLES Imaging Modalities Evidence Tables Table 1 Computed Tomography (CT) Imaging Author Clark (1986) 9 Reformatted sagittal images in the differential diagnosis meningiomas and adenomas with suprasellar

More information

Practical Approach to. Intraoperative Consultation (IOC)

Practical Approach to. Intraoperative Consultation (IOC) Texas Society of Pathologists 2013 92 nd Annual Meeting Neuropathology: Intraoperative Frozen Section Consultation for General Surgical Pathologists Gregory N. Fuller, MD, PhD Professor and Chief Neuropathologist

More information

Dr.Dafalla Ahmed Babiker Jazan University

Dr.Dafalla Ahmed Babiker Jazan University Dr.Dafalla Ahmed Babiker Jazan University Brain tumors are the second commonest malignancy in children Infratentorial tumors are more common As a general rule they do not metastasize out of the CNS, but

More information

Central Nervous System Tumors in Children. Dr.Mina Tajvidi

Central Nervous System Tumors in Children. Dr.Mina Tajvidi Central Nervous System Tumors in Children. Dr.Mina Tajvidi CNS Central nervous system (CNS) tumors account for 20% to 25% of all malignancies that occur in childhood(united States) The incidence is highest

More information

Pleomorphic xanthoastrocytomas (PXAs) are rare neoplasms. Pleomorphic Xanthoastrocytoma of Childhood: MR Imaging and Diffusion MR Imaging Features

Pleomorphic xanthoastrocytomas (PXAs) are rare neoplasms. Pleomorphic Xanthoastrocytoma of Childhood: MR Imaging and Diffusion MR Imaging Features Published July 3, 2014 as 10.3174/ajnr.A4011 ORIGINAL RESEARCH PEDIATRICS Pleomorphic Xanthoastrocytoma of Childhood: MR Imaging and Diffusion MR Imaging Features W. Moore, D. Mathis, L. Gargan, D.C. Bowers,

More information

Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ )

Childhood Brain and Spinal Cord Tumors Treatment Overview (PDQ ) 1 di 14 27/11/2016 17.42 NCBI Bookshelf. A service of the National Library of Medicine, National Institutes of Health. PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute

More information

Radiology of hypothalamic lesions: A pictorial essay depicting characteristic hypothalamic pathologies

Radiology of hypothalamic lesions: A pictorial essay depicting characteristic hypothalamic pathologies Radiology of hypothalamic lesions: A pictorial essay depicting characteristic hypothalamic pathologies Poster No.: C-2713 Congress: ECR 2010 Type: Scientific Exhibit Topic: Neuro Authors: A. J. B. Baxi,

More information

Original Research Article

Original Research Article Original Research Article Study Determining Correlation between Histopathological Diagnosis and MRI Findings of Posterior Fossa Tumors Srinivasarao S. Gummadidala 1, B. Jyothi 2 1 Assistant Professor,

More information

Role of Diffusion Weighted Imaging in Intracranial Tumors with Pathological Correlation

Role of Diffusion Weighted Imaging in Intracranial Tumors with Pathological Correlation ORIGINAL RESEARCH www.ijcmr.com with Pathological Correlation J. S. Aswini Jyothi, P. Sree Hari 2, V. Karuna 3 ABSTRACT Introduction: Intracranial tumors can occur in all age groups and can be grossly

More information

The Radiologic Evaluation of Glioblastoma (GBM) and Differentiation from Pseudoprogression

The Radiologic Evaluation of Glioblastoma (GBM) and Differentiation from Pseudoprogression The Radiologic Evaluation of Glioblastoma (GBM) and Differentiation from Pseudoprogression Alexis Roy, Harvard Medical School, Year III Our Patient AB: Clinical Presentation 53 year old female with a past

More information

Chordoid glioma: CT and MR features

Chordoid glioma: CT and MR features Chin J Radiol 2005; 30: 225-229 225 Chordoid glioma: CT and MR features YI-CHIH HSU HUNG-WEN KAO CHUNG-PING LO CHUN-JUNG JUAN SHY-CHYI CHIN CHENG-YU CHEN Department of Radiology, Tri-Service General Hospital

More information

Radiation necrosis is a well-described toxicity that has been

Radiation necrosis is a well-described toxicity that has been ORIGINAL RESEARCH PEDIATRICS Radiation Necrosis in Pediatric Patients with Brain Tumors Treated with Proton Radiotherapy X S.F. Kralik, C.Y. Ho, W. Finke, J.C. Buchsbaum, C.P. Haskins, and C.-S. Shih ABSTRACT

More information

Keep Imaging Simple: An Introduction To Neuroimaging

Keep Imaging Simple: An Introduction To Neuroimaging Keep Imaging Simple: An Introduction To Neuroimaging Meghan Elkins, OD, FAAO Please silence all mobile devices and remove items from chairs so others can sit. Unauthorized recording of this session is

More information

Introduction. In adults, the commonest tumors are gliomas, metastases and meniongiomas; most lie in the supratentorial compartment

Introduction. In adults, the commonest tumors are gliomas, metastases and meniongiomas; most lie in the supratentorial compartment Introduction Primary brain tumor 6 persons/100000/year Metastatic brain tumor 6 persons/100000/year 1 in 15 primary brain tumors occur in children under 15 years In adults, the commonest tumors are gliomas,

More information

Accuracy of intra-operative rapid diagnosis by Squash smear in CNS lesions An early institutional experience. KK Bansal,

Accuracy of intra-operative rapid diagnosis by Squash smear in CNS lesions An early institutional experience. KK Bansal, Accuracy of intra-operative rapid diagnosis by Squash smear in CNS lesions An early institutional experience. KK Bansal, Monika Bansal, Sanjeev Kishore, Anuradha K, Meena H, Dushyant G. Department of Neurosurgery

More information

NEURORADIOLOGY DIL part 5

NEURORADIOLOGY DIL part 5 NEURORADIOLOGY DIL part 5 Masses and tumors K. Agyem MD, G. Hall MD, D. Palathinkal MD, Alexandre Menard March/April 2015 OVERVIEW Introduction to Neuroimaging - DIL part 1 Basic Brain Anatomy - DIL part

More information

The central nervous system

The central nervous system Sectc.qxd 29/06/99 09:42 Page 81 Section C The central nervous system CNS haemorrhage Subarachnoid haemorrhage Cerebral infarction Brain atrophy Ring enhancing lesions MRI of the pituitary Multiple sclerosis

More information