THE BEST IN PROTON THERAPY TODAY AND TOMORROW

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1 THE BEST IN PROTON THERAPY TODAY AND TOMORROW

2 The figures speak for themselves As the leading provider of Proton Therapy, IBA is committed to making this advanced treatment available to cancer patients worldwide. Today, less than 1% of cancer patients have access to Proton Therapy, while research estimates that over 20% could benefit. This is why IBA has pledged to make Proton Therapy available to all people who need it. Olivier Legrain, Chief Executive Officer 20 % of RT patients could benefit from Proton Therapy 30 years leading innovation in Proton Therapy

3 100 % Committed to clinical innovation for the future Proton 65 % of PT patients are treated on IBA systems 40 institutions perfecting cancer care together

4 20 % of RT patients could benefit from Proton Therapy Increased in number of patients treated with Proton Therapy The Proton Therapy community is growing, as is awareness about it in the medical community.

5 Our mission: to help the 20% of rt patients that could benefit from proton therapy Typical cancer indications treated Before Today Head & neck 14% Other 13% Neuro 3% Breast 1% Lung 1% Brain 10% Head & Neck 10% Sarcoma 5% Retreatment 5% Pediatrics 15% Prostate 68% Lung 20% Genitourinary (Prostate included) 15% Gastro- Intestinal 20% The range of indications is expanding. For more information: on the clinical effectiveness of Proton Therapy, please contact us to receive: IBA Selected Proton Therapy Bibliography (08/15) IBA Series of Clinical White Papers. Contact us at: Or download them at:

6 30 years leading innovation in Proton Therapy We get all the details right Financing solutions Shielding and building design Project management

7 THE LARGEST PROTON THERAPY company Commitment to THE future and proven upgradability Unmatched training Speed Your safest investment in Proton Therapy Clinical training Maintenance and upgrades Throughput and workflow optimization

8 40 institutions perfecting cancer care together Newcomers in 2016 They trust us again

9 TESTIMONIALS On behalf of our local Institution and our multi-professional team, I would like to thank IBA for choosing our center and our city to host the 2016 Proteus User Meeting.The meeting was very fruitful and gave an opportunity for clinicians, physicists, technologists and administrators to interact and share experience and opinions. Dr. Maurizio Amichetti, Head Proton Therapy Department, APSS Trento The Texas Center for Proton Therapy is proud to be part of such a large network of IBA proton facilities. The recent User Meeting elucidated why IBA is a leader in this field and exhibited their commitment to improve lives through Proton Therapy. We look forward to our continued partnership with IBA to make a positive impact on the lives of cancer patients in Texas and beyond. Dr. Andrew Lee, Medical Director, Texas Center for Proton Therapy Willis-Knighton Cancer Center together with the Dallas Proton Center is proud to co-host the 2017 IBA Proteus User Meeting. Physicians, medical physicists, administrators and experts from 4 continents and at least 15 to 20 countries are expected to attend. This will be an excellent opportunity to show off the clinical advantages of IBA s compact single room system, the ProteusOne. Dr. Lane Rosen, Medical Director, Willis-Knighton Cancer Center

10 65 % of PT patients are treated on IBA systems World class clinical solutions More patients are treated on IBA systems than all our competitors combined proteus plus Fast delivery and room switching (< 10s) Room matching for maximum scheduling flexibility Image-guided IMPT proteus ONE The only compact solution with IMPT Efficiency in operation, 20% higher throughput Image-guided IMPT

11 Proteus PLUS Configured for excellence Proteus ONE Thing big, scale smart

12 100 % committed to clinical innovation for the future 281 patents and patent applications in Proton Therapy 36 worldwide research partners More than 10% of revenues invested in R&D

13 The IBA Proton Therapy Center of the future will: - Make Proton Therapy more affordable - Extend the range of clinical indications - Treat more patients, more efficiently

14 Proton therapy clinical references PROTON THERAPY CLINICAL REFERENCES Since we started developing Proton Therapy solutions, we have focused on collaboration and information sharing. We decided to take advantage of our day-to-day involvement with experienced clinical teams from Proton Therapy centers worldwide, and gather and share information on the use of Proton Therapy in oncology. We ve compiled this information in a series of White Papers on the latest scientific and clinical advances in Proton Therapy. Michel Closset, Clinical Director - Selected Proton Therapy Bibliography Proton Therapy in Practice: Clinical Indications - General Introduction - Proton Therapy in Practice: Clinical Indications - Pediatric Tumors Download them at: More clinical papers to come this year! If you want to subscribe to the latest information about Proton Therapy please send an to global.marketing@ibagroup.com.

15 Our experts will be pleased to answer your questions: Product Information - gregory Saive, ProteusOne Product Manager pone@iba-group.com - Weisheng Duan, Proteus Plus Product Manager pplus@iba-group.com - Simon Marcelis, PT Dosimetry Product Manager dosimetry-info@iba-group.com Clinical Information - michel Closset, Clinical Director medical.affairs@iba-group.com - Sofie Gillis, Clinical Solution Manager clinical.solution@iba-group.com Research and collaboration - damien Bertrand, Research and collaboration IBA_research.partnerships@iba-group.com Additional information - Jana Kulhankova, Marketing Associate global.marketing@iba-group.com

16 IBA Group IBAL01/6018 Leaflet April

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