Product Datasheet. Ly-6G6C Antibody (NIMP-R14) NB Unit Size: 0.05 mg. Store at 4C. Do not freeze. Publications: 23

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1 Product Datasheet Ly-6G6C Antibody (NIMP-R14) NB Unit Size: 0.05 mg Store at 4C. Do not freeze. Publications: 23 Protocols, Publications, Related Products, Reviews, Research Tools and Images at: Updated 6/6/2017 v.20.1 Earn rewards for product reviews and publications. Submit a publication at Submit a review at

2 NB Ly-6G6C Antibody (NIMP-R14) Product Information Unit Size Concentration Storage Clonality Clone Preservative Isotype Purity Buffer 0.05 mg 0.1 mg/ml Store at 4C. Do not freeze. Monoclonal NIMP-R14 No Preservative IgG2b Protein A or G purified PBS containing 0.1% BSA Page 1 of 4 v.20.1 Updated 6/6/2017 Product Description Host Rat Gene ID Gene Symbol Species LY6G6C Human, Mouse Reactivity Notes Human reactivity reported in scientific literature (PMID: ). Specificity/Sensitivity Immunogen Product Application Details Applications mouse Ly-6G6C Purified BALB/c mouse neutrophils Flow Cytometry, Functional, Immunoassay, Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin Recommended Dilutions Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry- Paraffin 1:50, Immunohistochemistry-Frozen 1:50, Functional, Immunoassay Application Notes Images The monoclonal antibody NIMP-R14 has been succesfully used to stain neutrophils for fluorescent activated cell sorting and in frozen and paraffin sections. Immunocytochemistry/Immunofluorescence was reported in scientific literature. Immunohistochemistry-Frozen: Ly-6G6C Antibody (NIMP-R14) [NB ] - Staining for Ly-6G/-6C FITC of frozen section of mouse spleen.

3 Publications Zahr A, Alcaide P, Yang J et al. Endomucin prevents leukocyte-endothelial cell adhesion and has a critical role under resting and inflammatory conditions. Nat Commun Feb 02 [PMID: ] (Flow, Human) This citation used the PE version of this antibody. Lopez AF, Strath M, Sanderson CJ. Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies Br J Haematol Van Lent PL, Blom A, Holthuysen AE et al. Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice J Leukoc Biol Tacchini-Cottier F, Zweifel C, Belkaid Y et al. An immunomodulatory function for neutrophils during the induction of a CD4+ Th2 response in BALB/c mice infected with Leishmania major J Immunol Navarini AA, Lang KS, Verschoor A et al. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections Proc Natl Acad Sci USA McLaren DJ, Strath M, Smithers SR. Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells Parasite Immunol Nagendra S, Schlueter AJ. Absence of cross-reactivity between murine Ly-6C and Ly-6G Cytometry A Lubberts E, Joosten LA, van Den Bersselaar L et al. Adenoviral vector-mediated overexpression of IL-4 in the knee joint of mice with collagen-induced arthritis prevents cartilage destruction J Immunol Van Lent PL, Blom A, Holthuysen AE et al. Monocytes/macrophages rather than PMN are involved in early cartilage degradation in cationic immune complex arthritis in mice J Leukoc Biol [PMID: ] Lopez AF, Strath M, Sanderson CJ. Differentiation antigens on mouse eosinophils and neutrophils identified by monoclonal antibodies Br J Haematol 1984 Jul [PMID: ] This citation used the FITC version of this antibody. Page 2 of 4 v.20.1 Updated 6/6/2017

4 McLaren DJ, Strath M, Smithers SR. Schistosoma mansoni: evidence that immunity in vaccinated and chronically infected CBA/Ca mice is sensitive to treatment with a monoclonal antibody that depletes cutaneous effector cells Parasite Immunol [PMID: ] Navarini AA, Lang KS, Verschoor A et al. Innate immune-induced depletion of bone marrow neutrophils aggravates systemic bacterial infections Proc Natl Acad Sci USA [PMID: ] More publications at Page 3 of 4 v.20.1 Updated 6/6/2017

5 Novus Biologicals USA E. Briarwood Avenue Centennial, CO USA Phone: Toll Free: Fax: Novus Biologicals Canada 461 North Service Road West, Unit B37 Oakville, ON L6M 2V5 Canada Phone: Toll Free: Fax: Novus Biologicals Europe 19 Barton Lane Abingdon Science Park Abingdon, OX14 3NB, United Kingdom Phone: (44) (0) Free Phone: Fax: (44) (0) General Contact Information Technical Support: Orders: General: Products Related to NB HAF005 Goat anti-rat IgG Secondary Antibody [HRP (Horseradish Peroxidase)] NB7115 Goat anti-rat IgG (H+L) Secondary Antibody [HRP] DDXCR03 Rat IgG2b Isotype Control NBP mg Ly-6G6C Antibody (NIMP-R14) [FITC] Limitations This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt. For more information on our 100% guarantee, please visit Earn gift cards/discounts by submitting a review: Earn gift cards/discounts by submitting a publication using this product: