Case Presentation Surgery Grand Round. Amid Keshavarzi, MD UCHSC 4/9/2006

Transcription

1 Case Presentation Surgery Grand Round Amid Keshavarzi, MD UCHSC 4/9/2006

2 Case Presentation 12 y/o female Presented to OSH after accidental swallowing of plastic fork in the bus, CXR/AXR form OSH did not show any foreign body, then she was transferred to TCH for further care. SH/FH: noncontributory PMH: None Medications: None ROS: Denied any difficulty breathing, nausea, vomiting. Mild LUQ pain. VS: BP: 107/65 / Pulse: 76 / Temp: 99.7 / Resp: 16 / SaO2: 98% Exam: Lungs: Clear to auscultation bilaterally. Unlabored respirations. Abdomen: Mild pain beneath left ribs. Otherwise normal exam

3 Case Presentation Initial CXR normal Initial esophagram negative for leak. Patient underwent gastroesophagoscopy. Following removal of the fork, repeat endoscopy revealed several areas of abrasion of both the stomach and esophagus, without significant bleeding or obvious perforation. Patient recovered form anesthesia and transferred to PACU.

4 Case Presentation In the PACU, found to be agitated, and on exam, she was tachypneic, decrease BS in the right chest, with right chest wall and neck crepitus. Right chest tube was placed, and esophagram was repeated.

5 Hospital Coarse Patient admitted to PICU. Initial VS: Temp: 99.7 / HR: 76 / RR: 16 / BP: 107/65 HD #1: Temp: 38.7 / HR 120 s / RR 20 s, WBC 18 / BP 112/49 OR for exploration. Underwent right thoracotomy, debridment of pleural cavity, repair of esophageal perforation with pleural patch. Found to have 1.5 cm vertical perforation of right lateral mid-esophagus, behind the azygus vein, with moderate pleural soiling and mediastinitis. Reinforced primary repair was performed using pleural patch.

6 Hospital Coarse POD # 1: Gastric feed started, HD stable, WBC: 14 POD # 2: Chest tubes were placed to waterseal, WBC: 10.8 POD # 3: Anterior chest tube D/C s, WBC: 7.5 POD # 4: No major event POD # 5: Esophagram negative for leak Postosterior chest tube D/C d NGT D/C d Diet advanced POD # 6: Discharged home

7 Esophageal Perforation: Historical Facts Esophageal perforation was first described ~ 250 years ago. In 1723, Herman Boerhaave first described barogenic esophageal rupture. In 1947, first reports of successful esophageal repair were performed by Barrett, Olsen and Clagett, separately. In 1952, Satinsky and Kron performed the first successful esophagectomy for perforation. In 1965, Mengoli and Klasser were the first described the conservative management.

8 Esophageal Perforation Esophageal perforations are associate with 15-30% mortality. Extremely high mortality before the era of antibiotics. Increase in frequency of iatrogenic injuries (60-70%) due to more frequent instrumentation in last 40 years. Most common site are areas of anatomic narrowing. Etiology of Esophageal Perforation 60% 50% 40% 30% 20% 10% 0% Instrumentation Foreign Body Operative Injury Etiology Others Cervical Abdominal Brinster CJ et al. : Ann Thorac Surg (2004) 77:

9 Esophageal Perforation Diagnosis: Contrast esophagography: Gastrographin study positive in 50% of cervical perforations and 75-80% of esophageal perforations Contrast studies have overall false negative rate of 10%. CT Flexible esophagoscopy Pleural effusion sampling Surgical options: Primary repair Reinforced primary repair Esophagectomy T-tube drainage Exclusion and diversion Thoracoscopic repair Delay primary repair Criteria for non-surgical treatment: Early diagnosis. Contained leak within neck or mediastinum. Drainage into esophageal lumen. Injury not related to neoplasm, in abdomen and not proximal to obstruction. No sign or symptom of sepsis. Availability experienced radiologist and CT surgeon. Brinster CJ et al. : Ann Thorac Surg (2004) 77: S. Hasan et al. Eur J CT Surgery 28 (2005) 7-10

10 Esophageal Perforation Brinster CJ et al. : Ann Thorac Surg (2004) 77:

11 Conservative management of iatrogenic esophageal perforation a viable option Clinical Findings in Iatrogenic Esophageal Perforation Retrospective study, over 10 years. 9/26 had carcinoma and 17/26 had benign pathology. 22/26 diagnosed within 6 h, and 4/26 over 24 h. Treatment plan : NPO, IVF, and Abx 22/26 (84.6%) success rate with this regimen. All four death (15.3%) was caused by other cases than mediastinitis, but all had contamination of pleural cavity. 46% of patient complicated with empyema. Conservative management give comparable to or better result than surgical intervention. Perforations which involves pleural or peritoneal cavity carries the worst prognosis. Shock Back pain Neck Emphysema Pyrexia Chest pain Extravasation to pleura Subdiaph. Exravasation Pneumoperitoneium Pneumothorax Pneumomediastinum LME X-Ray Findings 0% 10% 20% 30% 40% 50% 60% S. Hasan et al. Eur J CT Surgery 28 (2005) 7-10

12 Algorithm for Management of Esophageal Perforation Huber-Lang M et al. : Surg Today (2006) 36: Brinster CJ et al. : Ann Thorac Surg (2004) 77:

13 Conclusion Conservative management of esophageal perforation is a viable option but mostly dependent on patients pre-existing conditions. Primary repair of esophageal perforations with or without reinforcement is the best therapeutic approach.

14 References: Huber-Lang M, et al. : Esophageal perforation: principles of diagnosis and surgical management. Surg Today. 2006;36(4): Chambers AS, et al. : A new management approach for esophageal perforation. J Thorac Cardiovasc Surg Nov;130(5): Richardson JD et al. : Management of esophageal perforations: the value of aggressive surgical treatment. Am J Surg Aug;190(2): Hasan S, et al. : Conservative management of iatrogenic oesophageal perforations--a viable option. Eur J Cardiothorac Surg Jul;28(1):7-10. Eroglu A, et al. : Esophageal perforation: the importance of early diagnosis and primary repair. Dis Esophagus. 2004;17(1):91-4. Brinster CJ, et al. : Evolving options in the management of esophageal perforation. Ann Thorac Surg Apr;77(4):