Patronage requested A. ANICHINI (MILAN, ITALY) L. CERCHIETTI (NEW YORK, USA) M.P. COLOMBO (MILAN, ITALY) P. CORRADINI (MILAN, ITALY)

Transcription

1

2 Patronage requested Faculty A. ANICHINI (MILAN, ITALY) L. CERCHIETTI (NEW YORK, USA) M.P. COLOMBO (MILAN, ITALY) P. CORRADINI (MILAN, ITALY) F. DE BRAUD (MILAN, ITALY) M. DEL VECCHIO (MILAN, ITALY) M. DI NICOLA (MILAN, ITALY) G. DOTTI (HOUSTON, USA) M. FIGINI (MILAN, ITALY) G. INGHIRAMI (NEW YORK, USA) M. MASSAIA (TURIN, ITALY) 2 A. RAMBALDI (BERGAMO, ITALY)

3 Presentation Bio-immunotherapy of cancer is providing compelling proofs of clinical success in the comprehensive treatment of human malignancies. The increasing knowledge of the molecular mechanisms responsible for neoplastic transformation, the biology of cancer cells, and the immunological mechanisms regulating tumor-host interaction, allowed us to identify and apply more effective anti-cancer biogical and immunological treatments. To date, the immuno-biotherapy is a continuously evolving treatment modality and it is currently integrated into the treatment algorythms of several different tumors. Furthermore, elucidating resistance mechanisms and exploiting cancer vulnerabilities to therapeutics will ultimately improve cancer therapy and patient care. For these reasons, a multidisciplinary approach, including clinical and pre-clinical professionals, is required. This conference explores topics that will appeal to clinicians, as well as, basic, translational, and clinical scientists ranging from academics to industry. As in the past, the meeting will provide a highly interactive forum in which leading experts will discuss clinical and pre-clinical data, providing the audience with a broad overview of the most recent achievements in cancer biologic and immunologic therapy. 3

4 Friday, 30 January 2015 WELCOME COFFEE Registration Welcome remarks of Authorities Introduction M. Di Nicola and M. Del Vecchio (Milan, Italy) I SESSION: PRECLINICAL ASSAYS AND NOVEL BIOTARGETS Chairmen: G. Inghirami (New York, USA), M.P. Colombo (Milan, Italy) Humanized mice as preclinical model to guide targeted cancer therapy and drug development G. Inghirami (New York, USA) Discussion OX-40 is a fitness adaptor for T cells in the tumor microenvironment M. Colombo (Milan, Italy) Discussion Heat shock proteins and tumorigenesis L. Cerchietti (New York, USA) Discussion Rationale for immunotherapeutic combinations A. Anichini (Milan, Italy) Discussion Keynote Lecture Immune check-point inhibitors: clinical experience F. De Braud (Milan, Italy) BUFFET LUNCH 4

5 II SESSION: MONOCLONAL ANTIBODIES, CELL THERAPIES AND TK INHIBITORS Chairmen: M. Massaia (Turin, Italy), M. Di Nicola (Milan, Italy) Drug-conjugated antibody: Brentuximab and CD30+ hematological tumors P. Corradini (Milan, Italy) Discussion Bispecific monoclonal antibody 1. Principles and novel targets M. Figini (Milan, Italy) 2. Blinatumumab: clinical results A. Rambaldi (Bergamo, Italy) Discussion CAR-T cell therapies from hematologic malignancies to solid tumors G. Dotti (Houston, USA) Discussion Targeted therapies in melanoma M. Del Vecchio (Milan, Italy) Discussion Conclusions M. Di Nicola (Milan, Italy) 5

6 General Informations CONGRESS VENUE Aula Magna - Fondazione IRCCS Istituto Nazionale dei Tumori Via Venezian, 1 - MILAN SCIENTIFIC COMMITTEE Massimo Di Nicola Michele Del Vecchio Medical Oncology Department Fondazione IRCCS Istituto Nazionale dei Tumori Milan ORGANIZING SECRETARIAT Nadirex International Srl Via Riviera Pavia Tel /35 Fax info@nadirex.com CME PROVIDER NR. 265 Nadirex International Srl CME The request for CME credits has been submitted to the Italian Ministry of Health. ID Nr CME credits: Nr. 8,5 The Congress is intended for the following figures: - Physician (Ematology, Infectious Diseases, Oncology, Internal Medicine, Transfusional Medicine) - Biologist - Nurse - Biomedical laboratory technician In order to obtain CME credits, participants must: - Attend 100% of the sessions indicated in the programme - Fill in the personal data form, the form evaluating the event, and the learning questionnaire and give them to the Organizational Secretariat at the end of the Congress. The CME certificate will be sent by mail after the Congress to the address given on the personal data form. REGISTRATION The registration is free and includes: Partecipation in the conference work Congress Kit Certificate of Attendance CME credits Welcome coffee and lunch as scheduled REGISTRATION INSTRUCTIONS To register for the Congress you must fill in the form and send it to the Organizational Secretariat within 20 January The Organizational Secretariat will inform the participant that he or she has been registered for the Congress. 6

7 Registration Form Fill in using capital letters and send with payment to: NADIREX INTERNATIONAL s.r.l. Via Riviera, Pavia Fax info@nadirex.com PLEASE COMPLETE THE FOLLOWING DETAILS PHISYCIAN BIOLOGIST NURSE BIOMEDICAL LABORATORY TECHNICIAN Name... Surname... Profession... Discipline... Specialized... Clinic/Institute... Division/Department... Address... Postal Code... Town/City... Province... Tel.... Fax... Mobile Tel I authorise the use of my personal data in accordance with Legislative Decree 196/2003 Date... Signature... 7

8 CON IL CONTRIBUTO EDUCAZIONALE DI