Cancer Association of South Africa (CANSA) Fact Sheet on Essential Thrombocythaemia
|
|
- Alban Walsh
- 6 years ago
- Views:
Transcription
1 Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Essential Thrmbcythaemia Intrductin Essential thrmbcythaemia (ET) is nt a type f bld cancer as there are n cancerus cells. It is cnsidered a chrnic haematlgical malignancy and is smetimes referred t as a pre-leukaemic disrder which means that it may eventually cause ne r ther type f leukaemia. ET can result frm a mutatin in bld-frming stem cells, which causes bld cells (particularly platelets) t prduce uncntrllably. Hwever, research is still being dne t understand the additinal causes f ET. It is ne f the knwn myelprliferative neplasms (MPNs). Certain myelprliferative neplasms may becme acute myelid leukaemia (AML). Myelprliferative neplasms include chrnic myelgenus leukemia (CML), plycythaemia vera, primary myelfibrsis, essential thrmbcythaemia, chrnic neutrphilic leukaemia, and chrnic esinphilic leukaemia. Als called chrnic myelprliferative neplasm. The main types f MPN are: essential thrmbcythaemia plycythaemia vera myelfibrsis. [Picture Credit: Essential Thrmbcythaemia] ET is als knwn as essential thrmbcytsis, thrmbcytsis, and primary thrmbcytsis. Sme peple with essential thrmbcythaemia develp myelfibrsis. This is a cnditin in which the bne marrw becmes scarred. Peple with MPNs rarely develp leukaemia. (Cancer Supprt Cmmunity; Myelprliferative Disrder Research Cnsrtium). T understand ET ne must knw abut the rle f bne marrw. Bne marrw is part f the immune system, which prtects man frm infectin and disease. The marrw is in the spngy material fund inside bnes. This is where stem cells are made. Stem cells are bld Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 1
2 cells at their earliest stage f develpment. All bld cells grw frm stem cells. The three main types f bld cells are: red bld cells which carry xygen arund the bdy white bld cells which fight infectins platelets which help bld t clt t prevent bleeding. The bne marrw makes millins f bld cells every day. When the cells are mature they are released int the bld stream. In MPNs, the bne marrw makes t many f ne r mre types f bld cells (Macmillan Cancer Supprt). Incidence f Essential Thrmbcythaemia in Suth Africa The Natinal Cancer Registry (2008) des nt prvide any infrmatin regarding the incidence f Essential Thrmbcythaemia in Suth Africa. Causes f Essential Thrmbcythaemia (ET) The causes f ET are still unknwn. Abut half f ET patients have a mutatin called JAK2V617F within the bld-frming cells, which leads t many characteristic features f the disease. Sme risk factrs assciated with ET include: Gender - wmen are 1.5 times mre likely than men t develp the cnditin Age - peple lder than 60 are mst likely t develp the cnditin, althugh 20 percent f thse affected are yunger than 40 Envirnment - expsure t chemicals r t electrical wiring may increase an individual's risk fr the cnditin In all f the myelprliferative disrders, a stem cell that is capable f prducing red bld cells, certain white cells and platelets smehw ges haywire and n lnger keeps the bld elements prduced by the marrw in balance. In essential thrmbcythaemia, the marrw prduces t many platelets. (Jhns Hpkins Medicine; Myelprliferative Disrder Research Cnsrtium). Symptms f Essential Thrmbcythaemia (ET) Many patients d nt have any symptms. The diagnsis is ften made after bld cunts were dne as part f a rutine check-up which then reveals a high platelet cunt. Symptms, if present, include fatigue, r bld vessel disturbances r bleeding. Bld vessel disturbances r bleeding can result in: Headache Visin disturbances r silent migraines Dizziness r lightheadedness Fainting Cldness r blueness f fingers r tes Burning, redness, and pain r numbness in the hands and feet Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 2
3 Redness, thrbbing and burning pain in the hands and feet (erythrmelalgia) Mildly enlarged spleen Difficulty speaking r understanding speech (aphasia) Blurred, duble r decreased visin Easy bruising, nsebleeds r heavy perids Gastrintestinal bleeding r bld in the urine Erythrmelalgia is a rare and frequently devastating disrder that typically affects the skin f the feet r hands, r bth, and causes visible redness, intense heat and burning pain. It usually affects the lwer extremities (legs and feet) and upper extremities (arms and hands) including ther bdy parts like the face, ear r nse. It usually affects bth sides f the bdy, but has been knwn t nly affect ne side. The assciatin f pain and burning sensatins can be extremely severe. (Jhns Hpkins Medicine; May Clinic; Erythrmelalgia Assciatin). There are als ther metablic abnrmalities fund in patients with myelprliferative neplasms. These include: Elevated uric acid cunts are seen in abut half f MPN patients during the curse f their disease. If untreated, this leads t uric acid stnes, uric acid neurpathy, acute gut, and chrnic guty arthritis. Patients may experience jint pain as a result Lw chlesterl levels (hypchlestraemia), particularly in thse with enlarged spleens (splenmegaly) Elevated histamine levels. Symptms f increased histamine release include pruritis (itching characteristically prduced by bathing r shwering), heartburn, acid eructatin (gas), peptic ulcer, small bwel hypermtility, flushing and angineurtic edema (swelling f skin, mucus membranes r viscera). This ccurs in 2/3rds f myelprliferative disrder patients and crrelates with presence f elevated basphil cunt and hyperhistaminaemia Hypermetablism which cmmnly manifests as weakness and fatigue in the absence f anaemia (Myelprliferative Disrder Research Cnsrtium). Cmplicatins f Essential Thrmbcythaemia (ET) The abnrmal bld cltting f essential thrmbcythaemia can lead t a variety f ptentially serius cmplicatins, including: Pregnancy cmplicatins. While many wmen wh have thrmbcythaemia have nrmal, healthy pregnancies, they must ensure that their dctr regularly mnitrs their cnditin. Uncntrlled thrmbcythaemia may cause miscarriage, premature delivery, high bld pressure (preeclampsia), early separatin f the placenta frm the uterine wall (placental abruptin) and slw fetal grwth. The risk f cmplicatins may be reduced with regular checkups and medicatin Strke. A clt that blcks bld flw t the brain can cause a strke. If smene develps signs and symptms f a strke, get immediate medical attentin Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 3
4 Heart attack. A clt that bstructs bld flw t the heart can cause a heart attack. If smene develp signs and symptms f a heart attack, such as pressure, fullness r a squeezing pain in the centre f the chest lasting mre than a few minutes; pain extending t the shulder, arm, back, teeth r jaw; shrtness f breath; and sweating r clammy skin, get immediate medical attentin Essential thrmbcythaemia can als cause bleeding (haemrrhage) with significant bld lss. A small minrity f peple with essential thrmbcythaemia may later develp acute leukaemia r myelfibrsis, bth f which can be life-threatening: Acute leukaemia. Acute myelgenus leukaemia is a type f bld and bne marrw cancer that prgresses rapidly Myelfibrsis. This prgressive bne marrw disrder results in bne marrw scarring, severe anaemia, and enlargement f yur liver and spleen (May Clinic). Treatment f Essential Thrmbcythaemia (ET) ET is treated based n the persn s risk f cmplicatins, such as bleeding and bld cltting. Peple with n signs r symptms ther than an increased platelet cunt have a lwer risk f cmplicatins. These peple, especially thse with n ther cardivascular risk factrs, may nly need regular check-ups. Peple at high risk fr bleeding and cltting cmplicatins need treatment. Risks fr cltting cmplicatins include: previus clt cardivascular risk factrs high chlesterl, diabetes, smking, besity r high bld pressure Risks fr bleeding cmplicatins include: extremely high platelet cunt regular use f standard-dse aspirin r nn-steridal anti-inflammatry drugs (Canadian Cancer Sciety). Medical Disclaimer This Fact Sheet is intended t prvide general infrmatin nly and, as such, shuld nt be cnsidered as a substitute fr advice, medically r therwise, cvering any specific situatin. Users shuld seek apprpriate advice befre taking r refraining frm taking any actin in reliance n any infrmatin cntained in this Fact Sheet. S far as permissible by law, the Cancer Assciatin f Suth Africa (CANSA) des nt accept any liability t any persn (r his/her dependants/estate/heirs) relating t the use f any infrmatin cntained in this Fact Sheet. Whilst the Cancer Assciatin f Suth Africa (CANSA) has taken every precautin in cmpiling this Fact Sheet, neither it, nr any cntributr(s) t this Fact Sheet can be held respnsible fr any actin (r the lack theref) taken by any persn r rganisatin wherever Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 4
5 they shall be based, as a result, direct r therwise, f infrmatin cntained in, r accessed thrugh, this Fact Sheet. Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 5
6 Surces and References Canadian Cancer Sciety Cancer Supprt Cmmunity Cancer/Myelprliferative-Neplasms-2/What-is-Essential-thrmbcythemia-ET.html Erythrmelalgia Asscatin Essential Thrmbcythaemia =isch&sa=x&ei=ssyu5r8ujsbqagfgg&sqi=2&ved=0cayq_auaq&biw=1517&bih=71 4&dpr=0.9#facrc=_&imgdii=_&imgrc=J7h5nTaOV-c- TM%253A%3BxT2sEFx81lriCM%3Bhttp%253A%252F%252Fstatic.cdnseekingalpha.cm%252Fuplads%252F2014%252F1%252F834108_ _rId8.jpg%3Bhttp%253A%252F%252Fseekingalpha.cm%252Farticle%252F theacquisitin-f-mills-pharmaceuticals-put-anther-arrw-in-the-quiver-fgalena%3B544%3B319 Jhns Hpkins Medicine ers/essential_thrmbcytsis.html MacMillan Cancer Supprt May Clinic Myelprliferative Disrder Research Cnsrtium Researched and Authred by Prf Michael C Herbst [D Litt et Phil (Health Studies); D N Ed; M Art et Scien; B A Cur; Dip Occupatinal Health] Apprved fr Distributin by Ms Elize Jubert, Acting CEO December 2014 Page 6
Cancer Association of South Africa (CANSA)
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Lichen Planus Intrductin Lichen planus (LP) is a disease f the skin and/r mucus membranes that resembles lichen. A lichen is a cmpsite rganism that emerges
More informationCancer Association of South Africa (CANSA)
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet and Psitin Statement n Cannabis in Suth Africa Intrductin Cannabis is a drug that cmes frm Indian hemp plants such as Cannabis sativa and Cannabis indica.
More informationCancer Association of South Africa (CANSA) Fact Sheet on Being SunSmart with Infants,Toddlers and Children
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Being SunSmart with Infants,Tddlers and Children Intrductin Just ne blistering sunburn in childhd r adlescence mre than dubles a persn's chances f develping
More informationYou may have a higher risk of bleeding if you take warfarin sodium tablets and:
MEDICATION GUIDE Warfarin (WAR-far-in) Sdium (SO-dee-um) Tablets USP The 7.5 mg tablets cntain FD&C Yellw N. 5 (tartrazine), which may cause allergic-type reactins (including brnchial asthma) in certain
More informationFrequently Asked Questions: IS RT-Q-PCR Testing
Questins 1. What is chrnic myelid leukemia (CML)? 2. Hw des smene knw if they have CML? 3. Hw is smene diagnsed with CML? Frequently Asked Questins: IS RT-Q-PCR Testing Answers CML is a cancer f the bld
More informationVaccine Information Statement: PNEUMOCOCCAL CONJUGATE VACCINE
Vaccine Infrmatin Statement: PNEUMOCOCCAL CONJUGATE VACCINE Many Vaccine Infrmatin Statements are available in Spanish and ther languages. See www.immunize.rg/vis. Hjas de Infrmacián Sbre Vacunas están
More informationMy Symptoms and Medical History for Adult Chronic Immune Thrombocytopenia (ITP)
My Symptms and Medical Histry fr Adult Chrnic Immune Thrmbcytpenia (ITP) Call t talk t a registered nurse 1-855-7Nplate (1-855-767-5283), Mnday Friday, 9:00 AM 9:00 PM ET Indicatin Nplate is a man-made
More informationVaccine Information Statement: LIVE INTRANASAL INFLUENZA VACCINE
Vaccine Infrmatin Statement: LIVE INTRANASAL INFLUENZA VACCINE Many Vaccine Infrmatin Statements are available in Spanish and ther languages. See www.immunize.rg/vis. Hjas de Infrmacián Sbre Vacunas están
More informationBRCA1 and BRCA2 Mutations
BRCA1 and BRCA2 Mutatins ROBERT LEVITT, MD JESSICA BERGER-WEISS, MD ADRIENNE POTTS, MD HARTAJ POWELL, MD, MPH COURTNEY LEVENSON, MD LAUREN BURNS, MSN, RN, WHNP OBGYNCWC.COM v Cancer is a cmplex disease
More informationTop 10 Causes of Disability
Tp 10 Causes f Disability Disability can happen t anyne, f any age. Thugh sme may be the result f accidents r injuries that are unavidable, many disabilities are the result f diseases and health cnditins
More informationSwindon Joint Strategic Needs Assessment Bulletin
Swindn Jint Strategic Needs Assessment Bulletin Swindn Diabetes 2017 Key Pints: This JSNA gives health facts abut peple with diabetes r peple wh might get diabetes in Swindn. This helps us t plan fr medical
More informationInfluenza (Flu) Fact Sheet
Influenza (Flu) Fact Sheet What is the flu? The flu is a cntagius respiratry illness caused by influenza viruses. It can cause mild t severe illness, and at times can lead t death. Sme peple, such as lder
More informationOsteoporosis Fast Facts
Osteprsis Fast Facts Fast Facts n Osteprsis Definitin Osteprsis, r prus bne, is a disease characterized by lw bne mass and structural deteriratin f bne tissue, leading t bne fragility and an increased
More informationCONSENT FORM - TESTOSTERONE FOR TRANSGENDER CLIENTS
CONSENT FORM - TESTOSTERONE FOR TRANSGENDER CLIENTS Yu want t take teststerne t masculinize yur bdy. Befre taking it, there are several things yu need t knw abut. They are the pssible advantages, disadvantages,
More informationMEDICATION GUIDE Pioglitazone and Metformin Hydrochloride (PYE o GLI ta zone and met FOR min HYE-droe- KLOR-ide)Tablets, USP
MEDICATION GUIDE Piglitazne and Metfrmin Hydrchlride (PYE GLI ta zne and met FOR min HYE-dre- KLOR-ide)Tablets, USP Read this Medicatin Guide carefully befre yu start taking piglitazne and metfrmin hydrchlride
More informationHealth for Life Chiropractic At Cloverdale Mall Unit # The East Mall Etobicoke, ON, M9B 3Y
Health fr Life Chirpractic At Clverdale Mall Unit #143-250 The East Mall Etbicke, ON, M9B 3Y8 416-232-1822 416-232-0060 Child and Adlescent Health Questinnaire Name:_ Birth date: Address:_ Telephne: Medical
More informationMEDICATION GUIDE Pioglitazone (pie-oh-glit-ah-zohn) and Metformin (met-fore-min) Hydrochloride Tablets USP
MEDICATION GUIDE Piglitazne (pie-h-glit-ah-zhn) and Metfrmin (met-fore-min) Hydrchlride Tablets USP Read this Medicatin Guide carefully befre yu start taking piglitazne and metfrmin hydrchlride tablets
More informationRoActemra (tocilizumab) for Giant Cell Arteritis (GCA) subcutaneous (SC) formulation
RActemra (tcilizumab) fr Giant Cell Arteritis (GCA) subcutaneus (SC) frmulatin What yu shuld knw abut RActemra This brchure prvides key infrmatin t assist in the patient s understanding f the benefits
More informationName: Date: Period: Notes: The Blood and Lymphatic System
Name: Date: Perid: Cmpsitin f Bld and their Functins Red Bld Cells (aka ) Structure Ntes: The Bld and Lymphatic System D nt have a like ther cells d Cntain a specialized prtein called Hemglbin cntains
More informationCancer Association of South Africa (CANSA) Fact Sheet on Balanitis Xerotica Obliterans (BXO)
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Balanitis Xertica Obliterans (BXO) Intrductin Balanitis xertica bliterans (BXO), als knwn as lichen sclersus f the penis is a dermatlgical (skin) cnditin
More informationCONSENT FOR KYBELLA INJECTABLE FAT REDUCTION
CONSENT FOR KYBELLA INJECTABLE FAT REDUCTION INSTRUCTIONS This is an infrmed cnsent dcument which has been prepared t help yur Dctr infrm yu cncerning fat reductin with an injectable medicatin, its risks,
More informationHuman papillomavirus (HPV) refers to a group of more than 150 related viruses.
HUMAN PAPILLOMAVIRUS This infrmatin may help answer sme f yur questins and help yu think f ther questins that yu may want t ask yur cancer care team; it is nt intended t replace advice r discussin between
More informationBefore Your Visit: Mohs Skin Cancer Surgery
Befre Yur Visit: Mhs Skin Cancer Surgery Yur Kaiser Permanente Care Instructins Skin Cancer Infrmatin What is skin cancer? Skin cancers are tumrs, r malignancies, f the skin. Skin cancer is assciated with
More informationCancer Association of South Africa (CANSA)
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Childhd Sarcma f Sft Tissue Intrductin Sft tissue is a brad term ften used fr mesenchymal tissues that supprt and surrund mre well-defined rgans and
More informationMEDICATION GUIDE LEMTRADA (lem-tra-da) (alemtuzumab) Injection for intravenous infusion
MEDICATION GUIDE LEMTRADA (lem-tra-da) (alemtuzumab) Injectin fr intravenus infusin Read this Medicatin Guide befre yu start receiving LEMTRADA and befre yu begin each treatment curse. There may be new
More informationITP typically presents with the sudden appearance of a petechial rash, spontaneous bruising and/or bleeding in an otherwise well child.
Acute Immune Thrmbcytpenia Purpura (ITP) Backgrund Primary immune thrmbcytpenia (ITP) is an acquired immune mediated disrder characterised by islated thrmbcytpenia, defined as a peripheral bld platelet
More informationPackage leaflet: Information for the user. Fragmin Graduated Syringe 10,000 IU/ml Solution for Injection dalteparin sodium
Package leaflet: Infrmatin fr the user Fragmin Graduated Syringe 10,000 IU/ml Slutin fr Injectin dalteparin sdium Read all f this leaflet carefully befre yu start using this medicine because it cntains
More informationMEDICATION GUIDE. (Interferon alfa-2b)
MEDICATION GUIDE INTRON A (In-trn-aye) (Interfern alfa-2b) Read this Medicatin Guide befre yu start taking INTRON A, and each time yu get a refill. There may be new infrmatin. This infrmatin des nt take
More informationMEDICATION GUIDE. (fingolimod) capsules
MEDICATION GUIDE GILENYA (je-len-yah) (finglimd) capsules Read this Medicatin Guide befre yu start using GILENYA and each time yu get a refill. There may be new infrmatin. This infrmatin des nt take the
More informationManaging the Symptoms of Stroke
Unit 26: Recgnising and Managing the Symptms f Strke Unit reference number: F/616/7312 Level: 2 Unit type: Optinal Credit value: 3 Guided learning hurs: 28 Unit summary A strke can be a life-threatening
More informationA Phase I Study of CEP-701 in Patients with Refractory Neuroblastoma NANT (01-03) A New Approaches to Neuroblastoma Therapy (NANT) treatment protocol.
SAMPLE INFORMED CONSENT A Phase I Study f CEP-701 in Patients with Refractry Neurblastma NANT (01-03) A New Appraches t Neurblastma Therapy (NANT) treatment prtcl. The wrd yu used thrughut this dcument
More informationGlaucoma Interviews: Due Tuesday, May 22 nd
Glaucma Interviews: Due Tuesday, May 22 nd 1) Read the glaucma article well! It will explain what it is, plus tell yu sme symptms and risk factrs. Yu may want t use a highlighter r pen t mark imprtant
More informationAdult Preventive Care Guidelines
Adult Preventive Care Guidelines Gundersen is yur partner fr better health. We want t wrk with yu t make sure that yu and yur family are as healthy as pssible. That can be accmplished best if we wrk tgether
More informationIf you have any doubts or queries about your medication, please contact your doctor or pharmacist.
Bayer plc Bayer Huse Strawberry Hill Newbury Berkshire RG14 1JA United Kingdm Telephne: +44 (0)1635 563 000 Facsimile: +44 (0)1635 563 393 Cmpany Web Site: http://www.bayer.c.uk Due t regulatry changes,
More informationUnderstanding Your Total-Cholesterol-to-HDL Ratio
Understanding Yur Ttal-Chlesterl-t-HDL Rati Yur ttal-chlesterl-t-hdl rati is measured during a bld test called a lipid prfile. This wrksheet will help yu learn mre abut this rati. It will als help yu:
More informationPART III: CONSUMER INFORMATION
IMPORTANT: PLEASE READ PART III: CONSUMER INFORMATION Pr ZERIT Stavudine This leaflet is Part III f a three-part Prduct Mngaph published when ZERIT was apprved fr sale in Canada and is designed specifically
More informationMEDICATION GUIDE XARELTO (zah-rel-toe) (rivaroxaban) tablets
MEDICATION GUIDE XARELTO (zah-rel-te) (rivarxaban) tablets Read this Medicatin Guide befre yu start taking XARELTO and each time yu get a refill. There may be new infrmatin. This Medicatin Guide des nt
More informationImaging tests allow the cancer care team to check for cancer and other problems inside the body.
IMAGING TESTS This infrmatin may help answer sme f yur questins and help yu think f ther questins that yu may want t ask yur cancer care team; it is nt intended t replace advice r discussin between yu
More informationHYPERTENSION AN OVERVIEW. Compiled by. Campbell M Gold (2008) CMG Archives --()-- IMPORTANT
HYPERTENSION AN OVERVIEW Cmpiled by Campbell M Gld (2008) CMG Archives http://campbellmgld.cm IMPORTANT The health infrmatin cntained herein is nt meant as a substitute fr advice frm yur physician, r ther
More informationRisk factors in health and disease
Risk factrs in health and disease Index 1 Intrductin 2 Types f risk factrs 2.1 Behaviural risk factrs 2.2 Psychlgical risk factrs 2.3 Demgraphic risk factrs 2.4 Envirnmental risk factrs 2.5 Genetic risk
More informationCDC Influenza Division Key Points November 7, 2014
In this dcument: Summary Key Messages FluView Activity Update LAIV Effectiveness and Vaccinatin f Children H3N2 Match and Vaccinatin Vaccine Supply Summary Key Messages This week s FluView reprt indicates
More informationTendon problems can happen in people of all ages who take levofloxacin. Tendons are tough cords of tissue that connect muscles to bones.
Medicatin Guide LEVOFLOXACIN (LEE ve FLOX a sin) INJECTION, 25 mg/ml and LEVOFLOXACIN (LEE ve FLOX a sin) INJECTION in 5% Dextrse fr Intravenus Use Read this Medicatin Guide befre yu start taking levflxacin
More informationHand Pain & Problems
Anatmy f the hand: Hand Pain & Prblems The hand is cmpsed f many different bnes, muscles, and ligaments that allw fr a large amunt f mvement and dexterity. There are three majr types f bnes in the hand
More informationMEDICATION GUIDE. (canagliflozin) Tablets
MEDICATION GUIDE INVOKANA (in-v-kahn-uh) (canagliflzin) Tablets What is the mst imprtant infrmatin I shuld knw abut INVOKANA? INVOKANA can cause imprtant side effects, including: Dehydratin. INVOKANA can
More informationMEDICATION GUIDE QSYMIA (Kyoo sim ee uh) (phentermine and topiramate extended-release) Capsules CIV
MEDICATION GUIDE QSYMIA (Ky sim ee uh) (phentermine and tpiramate extended-release) Capsules CIV Read this Medicatin Guide befre yu start taking Qsymia and each time yu get a refill. There may be new infrmatin.
More informationPackage leaflet: Information for the user. Fragmin 10,000 IU/1 ml and 10,000 IU/4 ml Solution for injection dalteparin sodium
Package leaflet: Infrmatin fr the user Fragmin 10,000 IU/1 ml and 10,000 IU/4 ml Slutin fr injectin dalteparin sdium Read all f this leaflet carefully befre yu start using this medicine because it cntains
More information[Picture Credit: Felix Hoffman]
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet and Psitin Statement n Aspirin Intrductin Aspirin is part f a grup f medicatins called nn-steridal anti-inflammatry drugs (NSAIDs), but differs frm mst
More informationFlu Season Key Points ( )
2014-2015 Flu Seasn Key Pints (10-31-14) Cntents Overarching Framewrk f CDC Influenza Messaging... 3 Take 3 Messages... 3 Statements fr General Audiences... 4 Disease... 4 Vaccinatin... 6 Vaccinatin Timing...
More informationAnemia. There are three types of Anemia that effect EB patients. They are Iron Deficiency, Chronic Inflammatory and Nutritional.
Anemia Mst patients with Recessive Dystrphic Epidermlysis Bullsa are als Anemic. Anemia in EB is caused by many factrs and can becme very severe if nt treated. Anemia means nt having enugh red cells and
More informationBreast Cancer Awareness Month 2018 Key Messages (as of June 6, 2018)
Breast Cancer Awareness Mnth 2018 Key Messages (as f June 6, 2018) In this dcument there are tw sectins f messages in supprt f Cancer Care Ontari s Breast Cancer Awareness Mnth 2018: 1. Campaign key messages
More informationCDC Influenza Division Key Points MMWR Updates February 20, 2014
CDC Influenza Divisin Key Pints MMWR Updates In this dcument: Summary Key Messages Seasnal Influenza Vaccine Effectiveness: Interim Adjusted Estimates Influenza Surveillance Update: September 29, 2013-February
More informationAnnex III. Amendments to relevant sections of the Product Information
Changes t the Prduct infrmatin as apprved by the CHMP n 13 Octber 2016, pending endrsement by the Eurpean Cmmissin Annex III Amendments t relevant sectins f the Prduct Infrmatin Nte: These amendments t
More informationObesity/Morbid Obesity/BMI
Obesity/mrbid besity/bdy mass index (adult) Obesity/Mrbid Obesity/BMI Definitins and backgrund Diagnsis cde assignment is based n the prvider s clinical judgment and crrespnding medical recrd dcumentatin
More informationPercutaneous Nephrolithotomy (PCNL)
Percutaneus Nephrlithtmy (PCNL) What is a percutaneus nephrlithtmy? is the mst effective f the cmmnly perfrmed prcedures fr kidney stnes. It is the best prcedure fr large and cmplex stnes. T perfrm this
More informationMEDICATION GUIDE. Reference ID:
MEDICATION GUIDE GLYXAMBI (glik-sam-bee) (empagliflzin and linagliptin) Tablets Read this Medicatin Guide carefully befre yu start taking GLYXAMBI and each time yu get a refill. There may be new infrmatin.
More informationChapter 5 Anxiety Disorders
Test Review 2 Chapter 5 Anxiety Disrders Mst cmmn and effective frm f treatment = Expsure Anxiety Disrders Mst cmmn psychiatric disrders Phbias mst cmmn f the anxiety disrders Often Cmrbid with Majr Depressin
More informationo New or sudden changes in mood, behavior, actions, thoughts, or feelings, especially if severe.
MEDICATION GUIDE FLUOXETINE CAPSULES, USP (fl xʹ e teen) 10 mg and 20 mg Read the Medicatin Guide that cmes with fluxetine capsules befre yu start taking it and each time yu get a refill. There may be
More informationWHAT IS HEAD AND NECK CANCER FACT SHEET
WHAT IS HEAD AND NECK CANCER FACT SHEET This infrmatin may help answer sme f yur questins and help yu think f ther questins that yu may want t ask yur cancer care team; it is nt intended t replace advice
More informationMedication Guide MORPHINE SULFATE (mor-pheen) Oral Solution (CII)
Medicatin Guide MORPHINE SULFATE (mr-pheen) Oral Slutin (CII) IMPORTANT: Keep Mrphine Sulfate Oral Slutin in a safe place away frm children. Accidental use by a child is a medical emergency and can cause
More informationMEDICATION GUIDE REVLIMID (rev-li-mid) (lenalidomide) capsules What is the most important information I should know about REVLIMID?
MEDICATION GUIDE REVLIMID (rev-li-mid) (lenalidmide) capsules What is the mst imprtant infrmatin I shuld knw abut REVLIMID? Befre yu begin taking REVLIMID, yu must read and agree t all f the instructins
More informationUnderstanding and Recognizing Anxiety
Understanding and Recgnizing Anxiety Mst peple d nt recgnize their anxiety fr what it is, and instead think there is smething mre serius ging n. Myth: Reading, thinking, and learning abut anxiety will
More informationHead and neck cancers are often treated with radiotherapy. Radiotherapy can lead to faster rates of tooth decay and poor healing in the mouth.
DENTAL EXTRACTION This infrmatin aims t help yu understand the peratin, what is invlved and sme cmmn cmplicatins that may ccur. It may help answer sme f yur questins and help yu think f ther questins that
More informationRead all of this leaflet carefully before you start taking this medicine.
Due t regulatry changes, the cntent f the fllwing Patient Infrmatin Leaflet may vary frm the ne fund in yur medicine pack. Please cmpare the 'Leaflet prepared/revised date' twards the end f the leaflet
More informationTick fever is a cattle disease caused by any one of the following blood parasites:
Tick fever Tick fever is a cattle disease caused by any ne f the fllwing bld parasites: Babesia bvis Babesia bigemina Anaplasma marginale These parasites are all transmitted by the cattle tick (Bphilus
More informationKey Points Enterovirus D68 in the United States, 2014 Note: Newly added information is in red.
Key Pints Entervirus D68 in the United States, 2014 Nte: Newly added infrmatin is in red. The United States is currently experiencing a natinwide utbreak f entervirus D68 (EV-D68) assciated with severe
More informationAdvantage EAP Employee Assistance Program
Advantage EAP Emplyee Assistance Prgram July 2014 In This Issue What might we face? Symptms f SAD Seasnal changes in biplar disrder Tips fr cmbating summer truble When t seek help Tips fr helping thse
More informationHealth Science Ch. 16 Cancer Lecture Outline
Cancer Leading cause f disease-related death amng peple under age 75 Secnd leading cause f death Evidence supprts that mst cancers culd be prevented by simple lifestyle changes Tbacc is respnsible fr abut
More information/0515 Medication Guide Aripiprazole Tablets
8415721/0515 Medicatin Guide Aripiprazle Tablets (air-eh-pip-rah-zle) Read this Medicatin Guide befre yu start taking aripiprazle tablets and each time yu get a refill. There may be new infrmatin. This
More informationThe Excretory System. 4 The Excretory System.notebook. May 24, 2017
4 The Excretry System.ntebk The Excretry System OSMOREGULATION (WATER BALANCE) Mst marine invertebrates are smcnfrmers, meaning the cncentratin f slutes in their bdy fluid is equal t that f their envirnment.
More informationINTRODUCTION TO THE CIRCULATORY SYSTEM
INTRODUCTION TO THE CIRCULATORY SYSTEM What des bld d? 5. What makes this pssible? : In rder fr there t be an efficient exchange f xygen, waste and nutrients there must be a high surface area between the
More informationReferral Criteria: Inflammation of the Spine Feb
Referral Criteria: Inflammatin f the Spine Feb 2019 1 5.7. Inflammatin f the Spine Backgrund Ankylsing spndylitis and axial spndylarthrpathy are fund in arund 0.3-1.2% f the ppulatin. Spndylarthritis encmpasses
More informationCRANIOFACIAL RESECTION
CRANIOFACIAL RESECTION This infrmatin aims t help yu understand the peratin, what is invlved and sme cmmn cmplicatins that may ccur. It may help answer sme f yur questins and help yu think f ther questins
More informationWhat is Asthma? A collaborative effort of Children s Hospital of Pittsburgh of UPMC and The Pennsylvania Child Welfare Resource Center
A cllabrative effrt f Children s Hspital f Pittsburgh f UPMC and The Pennsylvania Child Welfare Resurce Center What is Asthma? Jennifer E. Wlfrd, DO, MPH, FAAP Children s Hspital f Pittsburgh, Divisin
More informationFIGHT DEMENTIA ACTION PLAN
FIGHT DEMENTIA ACTION PLAN DEMENTIA IS A HEALTH PRIORITY Dementia will be the majr health prblem f this century. Over ne millin Australians are already affected by the disease themselves r are caring fr
More informationALCAT FREQUENTLY ASKED QUESTIONS
1. Is fasting required befre taking the Alcat Test? N. It is recmmended t drink water and t avid stimulants like caffeine prir t the test. 2. With regard t testing children, must a child be a certain age
More informationZika Virus. Where has Zika virus been found? Zika in the United States and its territories:
Where has Zika virus been fund? Zika Virus Prir t 2015, Zika virus utbreaks have ccurred in areas f Africa, Sutheast Asia, and the Pacific Islands. In May 2015, the Pan American Health Organizatin (PAHO)
More informationAccess to Heme Treatment in Canada - Survey 2018
Access t Heme Treatment in Canada - Survey 2018 The Canadian Assciatin fr Prphyria/Assciatin Canadienne de Prphyrie (CAP/ACP) asserts that patients with acute prphyria shuld have access t Hemin treatment,
More informationCDC Influenza Technical Key Points February 15, 2018
CDC Influenza Technical Key Pints In this dcument: Summary Key Pints U.S. Vaccine Effectiveness U.S. Flu Activity Update Summary Key Pints On Thursday, tw influenza-related reprts appeared in the Mrbidity
More informationUnderstanding your thumb osteoarthritis
Understanding yur thumb stearthritis Intrductin The CMC jint is ne f the mst imprtant jints f the thumb and hand due t its wide range f mtin. Over time, the CMC jint is subject t large and repeated frces
More informationName of procedure: Removal of submandibular salivary gland
Oral facial surgery Surgical prcedure infrmatin leaflet Name f prcedure: Remval f submandibular salivary gland This leaflet explains sme f the benefits, risks and alternatives t the peratin. We want yu
More informationSafety of HPV vaccination: A FIGO STATEMENT
FIGO Statement n HPV Vaccinatin Safety, August 2nd, 2013 Safety f HPV vaccinatin: A FIGO STATEMENT July, 2013 Human papillmavirus vaccines are used in many cuntries; glbally, mre than 175 millin dses have
More informationPain relief after surgery
Pain relief after surgery Imprtant infrmatin fr patients www.mchft.nhs.uk We care because yu matter This leaflet is designed t help yu cntrl any pain yu may have at hme fllwing yur peratin. Please read
More informationCancer Association of South Africa (CANSA)
Cancer Assciatin f Suth Africa (CANSA) Fact Sheet n Adult Acute Prmyelcytic Leukaemia (APL) Intrductin Acute prmyelcytic leukaemia (APL) is a frm f cancer that affects the stem cells which prduce myelid
More informationKey Points Enterovirus D68 in the United States, 2014 Note: Newly added information is in red.
Key Pints Entervirus D68 in the United States, 2014 Nte: Newly added infrmatin is in red. Over the last several mnths, the United States has experienced a natinwide utbreak f entervirus D68 (EV- D68) assciated
More informationPHARYNGO-OESOPHAGECTOMY
PHARYNGO-OESOPHAGECTOMY This infrmatin aims t help yu understand the peratin, what is invlved and sme cmmn cmplicatins that may ccur. It may help answer sme f yur questins and help yu think f ther questins
More information2. How are screening and diagnostic mammograms different?
Mammgrams cmprises public dmain material frm the Natinal Cancer Institute at the Natinal Institutes f Health, an agency f the U.S. Department f Health and Human Services. Mammgrams Key Pints A mammgram
More informationWARNING: FATAL AND SERIOUS TOXICITIES: SEVERE DIARRHEA AND CARDIAC TOXICITIES
INDICATION FARYDAK (panbinstat) capsules, a histne deacetylase inhibitr, in cmbinatin with brtezmib and dexamethasne, is indicated fr the treatment f patients with multiple myelma wh have received at least
More informationFrequently asked questions: Influenza A (H1N1)v
July 30 th 2009 V1.0 Frequently asked questins: Influenza A (H1N1)v (Swine Flu) infrmatin fr parents The fllwing advice is fr parents f children in all educatinal institutins, including crèches, childcare,
More informationHealth Screening Record: Entry Level Due: August 1st MWF 150 Entry Year
Health Screening Recrd: Entry Level MIDWIFERY EDUCATION PROGRAM HEALTH SCREENING REQUIREMENTS (Rev. June 2017) 1. Hepatitis B: Primary vaccinatin series (3 vaccines 0, 1 and 6 mnths apart), plus serlgic
More informationDRAFT Policy for the Management of Ear Wax
Clinical Cmmissining Grup (CCG) Treatment Plicy NHS Birmingham and Slihull Clinical Cmmissining Grup NHS Sandwell and West Birmingham Clinical Cmmissining Grup DRAFT Plicy fr the Management f Ear Wax 1
More informationPatrick J McGahan, MD Orthopaedic Surgeon Specializing in Sports Medicine/Shoulder Reconstruction Surgery Instructions Hip
Patrick J McGahan, MD Orthpaedic Surgen Specializing in Sprts Medicine/Shulder Recnstructin 2801 K St, Ste 330, Sacrament, CA, 95816 (p) 916-733-5049 (f) 916-733-8914 www.patrickmcgahanmd.cm Befre Surgery
More informationDEMENTIA. DESCRIPTION: a progressive, degenerative disease of the brain, which causes impairment of thinking and memory
DEMENTIA Dementia a syndrme cnsisting f a number f symptms including lss f memry, judgment and reasning, and changes in md and behavir the changes may affect a persn's ability t functin at wrk, in scial
More informationBP Thresholds for Medical Review
BP Threshlds fr Medical Review Wmen presents t GP pstnatally with high bld pressure r referred t GP by midwife GP t review patient n the same day if BP>150/100. If BP (dne by midwife) persistently 140-149/90-99,
More informationPediatric Health History Form
Pediatric Health Histry Frm Child s Name Date f Birth Mther s Name Father s Name Parent Cncerns - Please explain any ther cncerns r questins yu have abut yur child Des yur child have any allergies? Yes
More informationDr. Tozzi s and Dr. Roehrig s Patient Guide to Total Hip Replacement
Dr. Tzzi s and Dr. Rehrig s Patient Guide t Ttal Hip Replacement This guide is meant t help yu better understand yur upcming hip surgery. It is generalized infrmatin, and individual patients have unique,
More informationPackage leaflet: Information for the user. Dacepton 5 mg/ml Solution for infusion Apomorphine hydrochloride hemihydrate
Package leaflet: Infrmatin fr the user Daceptn 5 mg/ml Slutin fr infusin Apmrphine hydrchlride hemihydrate Read all f this leaflet carefully befre yu start using this medicine because it cntains imprtant
More informationDiabetes Canada Pre-Budget Consultation Submission. Standing Committee on Finance and Economic Affairs. Government of Ontario.
Diabetes Canada 2018 Pre-Budget Cnsultatin Submissin Standing Cmmittee n Finance and Ecnmic Affairs Gvernment f Ontari January 17, 2018 1 Executive Summary Tday, abut 4.4 millin Ontarians, r 29 per cent
More informationSuicidal thoughts or actions:
MEDICATION GUIDE Venlafaxine (VEN la fax een) Hydrchlride Extended-release Capsules USP Read the Medicatin Guide that cmes with venlafaxine hydrchlride extended-release capsulesbefre yu start taking them
More informationTOP TIPS Lung Cancer Update Dr Andrew Wight Consultant respiratory Physician - WUTH
Tpic Circulatin list In case f query please cntact Executive Summary TOP TIPS Lung Cancer Update Dr Andrew Wight Cnsultant respiratry Physician - WUTH All Wirral GP s JaneFletcher2@nhs.net Dear Clleagues,
More information