Liver cancer and normal cell lines
|
|
|
- Benjamin Jacobs
- 6 years ago
- Views:
Transcription
1 The Essentials of Life Science Research Globally Deed Liver cancer and normal cell lines ATCC No. Name Tissue Cell Type Disease Oganism Age Ethnicity Genes Expressed HTB-79 Capan-1 pancreas: adenocarcinoma Homo sapiens 40 years Caucasian mucin, Blood Type A; Rh+; HLA A2, A9, B13, B17 HTB-52 SK-HEP-1 /ascites Endothelial adenocarcinoma Homo sapiens 52 years Caucasian 8306 MC/9 mast cell Allergen 13 days histamine; leukotrienes 1439 clone 9 Epithelial carcinogenesis HB-8108 B72.3 HB-8107 B25.2 HB-8106 B6.2 HB-8110 B38.1, spleen,, spleen,, spleen,, spleen, Carcinoma Carcinoma Carcinoma, sarcoma Carcinoma, sarcoma 4 weeks 2064 DMS 153 lung: carcinoma; small cell lung cancer Homo sapiens 44 years Caucasian adrenocorticotropin (adrenocorticotropic hormone, ACTH); bombesin; calcitonin; calcitonin gene related peptide (CGRP); oxytocin - neurophysin (OT-NP); 17 beta estradiol, Leu 7 +; My23 +; CD11b SU pancreas: ductal carcinoma Homo sapiens 57 years Caucasian carcinoembryonic antigen (CEA) 5822 NCI-N87 [N87] stomach: gastric carcinoma Homo sapiens myc +; erb B SNU-182 grade III/IV, hepatocellular carcinoma Homo sapiens 2238 SNU-423 grade III/IV, pleomorphic hepatocellular carcinoma 24 years Asian Blood Type O; Rh + Homo sapiens 40 years Asian Blood Type B; Rh SNU-449 grade II-III/IV, hepatocellular carcinoma Homo sapiens 52 years Asian 2236 SNU-475 grade II-IV/V, hepatocellular carcinoma Homo sapiens 43 years Asian Blood Type AB; Rh +
2 2237 SNU-387 grade IV/V, pleomorphic hepatocellular carcinoma 7549 Hs 817.T hepatic ductal carcinoma Homo sapiens 41 years Asian Blood Type O; Rh + unknown, either human or mouse 2117 LMH hepatocellular carcinoma Gallus gallus 2118 LMH/2A hepatocellular carcinoma Gallus gallus C3A [HepG2/ C3A, derivative of Hep G2 (ATCC HB- 8065)] C3A [HepG2/ C3A, derivative of Hep G2 (ATCC HB- 8065)] hepatocellular carcinoma Homo sapiens hepatocellular carcinoma Homo sapiens 15 years adolescent 16 years adolescent Caucasian Caucasian HEP G2/2.2.1 hepatocellular carcinoma Homo sapiens 15 years Caucasian 2233 SNU-398 hepatocellular carcinoma Homo sapiens 42 years Asian Blood Type O; Rh + HB-8064 HB-8065 Hep 3B2.1-7 [Hep 3B, Hep-3B, Hep3B] Hep G2 [HEPG2] hepatocellular carcinoma Homo sapiens hepatocellular carcinoma Homo sapiens 2406 PLHC-1 hepatocyte hepatocellular carcinoma Pan troglodytes HB Hep G2/SF hepatocellular carcinoma Homo sapiens 8 years juvenile 9 years juvenile Black Black alpha-fetoprotein (alpha fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin; (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen;, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein) alpha-fetoprotein (alpha fetoprotein); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1-antitrypsin); transferrin; alpha1 antichymotrypsin; (alpha-1-antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen;, complement (C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein); alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol-binding protein) alpha fetoprotein (alpha-fetoprotein); hepatitis B surface antigen (HBsAg); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1- antitrypsin); transferrin;, alpha1 antichymotrypsin (alpha-1- antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen; complement (C3, C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein);, alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol- alpha fetoprotein (alpha-fetoprotein); hepatitis B surface antigen (HBsAg); albumin; alpha2 macroglobulin (alpha-2-macroglobulin); alpha1 antitrypsin (alpha-1- antitrypsin); transferrin;, alpha1 antichymotrypsin (alpha-1- antichymotrypsin); haptoglobin; ceruloplasmin; plasminogen; complement (C3, C4); C3 activator; fibrinogen; alpha1 acid glycoprotein (alpha-1 acid glycoprotein);, alpha2 HS glycoprotein (alpha-2-hs-glycoprotein); beta lipoprotein (beta-lipoprotein); retinol binding protein (retinol- cytochrome P450 (CYP) 2 Order online at call , , or contact your local distributor.
3 8024 PLC/PRF/5 Alexander cells hepatoma Homo sapiens hepatitis virus B surface antigen (HBsAg) 2082 WCH-17 hepatoma Marmota monax 1830 Hepa 1-6 hepatoma 2026 Hepa-1c1c7 hepatoma cytochrome P450IA BpRc1 hepatoma cytochrome P450IA tao BpRc1 hepatoma cytochrome P450IA c12 (B15ECiii2) epithelial hepatoma 2711 c37 (B7IFi1) epithelial hepatoma 2712 vt{2} epithelial hepatoma c1 (B6NLxv1c2) c4 (B13NBii1) hepatoma epithelial hepatoma CCL-144 MH1C1 hepatoma 1548 H-4-II-E hepatoma 1578 H4TG hepatoma 1600 H4-II-E-C3 hepatoma 1710 RTH-149 hepatoma 1601 McA-RH7777 hepatoma; Morris hepatoma McA-RH8994 hepatoma; Morris hepatoma N1-S1 Fudr hepatoma; Novikoff hepatoma TIB spleen, B Lymphoma 2254 AML12 hepatocyte normal 3 months 5892 NCI-H1755 [H1755] lung: stage 4, adenocarcinoma; non-small cell lung cancer Homo sapiens 65 years Caucasian albumin, alpha fetoprotein (AFP, alpha-fetoprotein); albumin; alpha 1 antitrypsin (alpha-1-antitrypsin); amylase rat serum albumin; complement components (especially C9) tyrosine aminotransferase; albumin; transferrin; prothrombin alpha-fetoprotein (AFP, alpha fetoprotein) alpha-fetoprotein (AFP); alpha fetoprotein immunoglobulin; monoclonal antibody; against mouse B cell () precursors (CD45RA), The epitope recognized requires expression of exon A. albumin; human transforming growth factor alpha (TGF alpha); mouse TGF alpha. Expression of specific proteins decreases with time in culture, but is reactivated by growing the cells in serum free medium. Order online at call , , or contact your local distributor. 3
4 5978 NCI-H735 [H735] lung: 2706 THLE-2 /left lobe stage E, carcinoma; small cell lung cancer These immortalized human cells constitute an in vitro model for pharmacotoxicological studies and for the investigation of etiology and pathogenesis of human hepatocellular carcinoma. Homo sapiens 58 years Caucasian Homo sapiens 2643 ZFL [ZF-L] Danio rerio HB CCL-9.1 AC133.1 Lymph node,, bone, Peripheral blood, Blood, Bone marrow lymphoblast B THLE-3 /left lobe Homo sapiens NCTC clone 1469 [derivative of NCTC 721] newborn H-2k 1638 NMuLi weanling 1995 H2.35 hepatocyte 6 weeks 2390 FL83B hepatocyte 6447 NMu3Li 15 to 17 days gestation TIB-73 BNL CL.2 embryo TIB-74 BNL SV A.8 embryo TIB-75 BNL 1ME A.7R.1 embryo TIB-76 BNL 1NG A.2 embryo 6194 OHH1.Li 2301 SOB-15 epithelial 1442 BRL 3A fibroblast 2452 Sl/Sl4 /stroma Mast Cell embryo Sl/Sl4 hscf220 Sl/Sl4 hscf248 /stroma Mast Cell embryo fawn immunoglobulin; monoclonal antibody; against a subset of human CD34 antigens The cells express cytokeratin 18 and albumin in early passage, whereas higher-passage cells in logarithmic-phase growth also express cytokeratin 19. cholesterol; glycogen /stroma Mast Cell embryo stem cell factor (SCF) somatomedin like multiplication stimulating activity (MSA) 4 Order online at call , , or contact your local distributor.
5 10998 L.N temperature sensitive T antigen HB HB-8770 FHCR /FH5 [FH5] F.Li, spleen pre-b lymphoblast B fetus immunoglobulin; mu heavy chain (not secreted) Zalophus californianus immunoglobulin; monoclonal antibody; against trifucosylated type 2 chain glycolipids PHONE tech@atcc.org WEB CB American Type Culture Collection. The ATCC trademark and trade name, any and all ATCC catalog numbers and any other trademarks listed in this publication are trademarks of the American Type Culture Collection unless indicated otherwise. These products are for laboratory use only. Not for human or diagnostic use. ATCC products may not be resold, modified for resale, used to provide commercial services or to manufacture commercial products without prior ATCC written approval.
America, Hershey, PA Australia, Melbourne, VIC Europe, Munich
America, Hershey, PA Australia, Melbourne, VIC Europe, Munich info@vivopharm.com www.vivopharm.com Bladder MB-9-luc 2 Mouse urinary bladder carcinoma yes yes yes C57BL/6 2 Bone UMR-106 Rat osteosarcoma
Analyte Specimen Demographic Reference Range Units
Acetone Negative titer Alanine aminotransferase (ALT/SGPT) 10-49 U/L Albumin 3.2-4.8 g/dl Alcohol < 10 Alpha-fetoprotein (AFP) < 1.3-8.1 ng/ml Alkaline phosphatase 0 7 days 7 30 days 1 3 3 6 6 12 1 3 3
Tumor Immunology. Tumor (latin) = swelling
Tumor Immunology Tumor (latin) = swelling benign tumor malignant tumor Tumor immunology : the study of the types of antigens that are expressed by tumors how the immune system recognizes and responds to
TECHNICAL NOTE. Accurate and fast proteomics analysis of human plasma with PlasmaDive and SpectroDive
TECHNICAL NOTE Accurate and fast proteomics analysis of human plasma with PlasmaDive and SpectroDive In this technical note you will learn about: Step-by-step set-up of parallel reaction monitoring (PRM)
CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS Emerging Assays, and Companies Developing New Technologies and Products.
CURRENT AND EMERGING CANCER DIAGNOSTIC TESTS Emerging Assays, and Companies Developing New Technologies and Products Table of Contents Major Current And Emerging Cancer Diagnostic Tests 1. Introduction
Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2
![Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2](/thumbs/88/116309357.jpg "Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-2 Mouse urinary bladder carcinoma C57BL/6 2")
America, Hershey, PA Australia, Melbourne, VIC Europe, Munich info@vivopharm.com www.vivopharm.com Tissue Bladder Species Tumor Type Comment for in vivo work Lead Time for in vivo studies [weeks] MB-49-luc-
TUMOR M ARKERS MARKERS
TUMOR MARKERS M.Shekarabi IUMS Definition Many cancers are associated with the abnormal production of some molecules l which h can be measured in plasma. These molecules are known as tumor markers. A good
Sexually Transmitted Infections
TM Sexually Transmitted Infections THE ESSENTIALS OF LIFE SCIENCE RESEARCH GLOBALLY DELIVERED SEXUALLY TRANSMITTED INFECTIONS Sexually transmitted infections (STIs) pose a major socioeconomic threat to
Tumour Markers. For these reasons, only a handful of tumour markers are commonly used by most doctors.
Tumour Markers What are Tumour Markers? Tumour markers are substances that can be found in the body when cancer is present. They are usually found in the blood or urine. They can be products of cancer
Critical Raw Materials. Critical Raw Materials. Cell Culture Derived Antigens and Antibodies
Critical Raw Materials Critical Raw Materials Cell Culture Derived Antigens and Antibodies Critical Raw Materials Antigens and antibodies for tumor markers, pituitary hormones, cardiac markers and fertility
Supporting Information: Protein Corona Analysis of Silver Nanoparticles Exposed to Fish Plasma
Supporting Information: Protein Corona Analysis of Silver Nanoparticles Exposed to Fish Plasma Jiejun Gao 1, Lu Lin 2, Alexander Wei 2,*, and Maria S. Sepúlveda 1,* 1 Department of Forestry and Natural
Tumor Markers Yesterday, Today & Tomorrow. Steven E. Zimmerman M.D. Vice President & Chief Medical Director
Tumor Markers Yesterday, Today & Tomorrow Steven E. Zimmerman M.D. Vice President & Chief Medical Director Tumor Marker - Definition Substances produced by cancer cells or other cells in response to cancer
COURSE: Medical Microbiology, MBIM 650/720 - Fall TOPIC: Antigen Processing, MHC Restriction, & Role of Thymus Lecture 12
COURSE: Medical Microbiology, MBIM 650/720 - Fall 2008 TOPIC: Antigen Processing, MHC Restriction, & Role of Thymus Lecture 12 FACULTY: Dr. Mayer Office: Bldg. #1, Rm B32 Phone: 733-3281 Email: MAYER@MED.SC.EDU
The Development of Lymphocytes: B Cell Development in the Bone Marrow & Peripheral Lymphoid Tissue Deborah A. Lebman, Ph.D.
The Development of Lymphocytes: B Cell Development in the Bone Marrow & Peripheral Lymphoid Tissue Deborah A. Lebman, Ph.D. OBJECTIVES 1. To understand how ordered Ig gene rearrangements lead to the development
The Major Histocompatibility Complex (MHC)
The Major Histocompatibility Complex (MHC) An introduction to adaptive immune system before we discuss MHC B cells The main cells of adaptive immune system are: -B cells -T cells B cells: Recognize antigens
What is Liver Cancer? About the Liver
Your liver is important and it has many functions. The top three are that it cleans your blood of toxins, gives you energy and produces bile for digestion. What is Liver Cancer? Cancer starts when cells
A 53 year-old woman with a lung mass, right hilar mass and mediastinal adenopathy.
November 2015 Case of the Month A 53 year-old woman with a lung mass, right hilar mass and mediastinal adenopathy. Contributed by: Rasha Salama, M.D., IU Department of Pathology and Laboratory Medicine
immunity defenses invertebrates vertebrates chapter 48 Animal defenses --
defenses Animal defenses -- immunity chapter 48 invertebrates coelomocytes, amoebocytes, hemocytes sponges, cnidarians, etc. annelids basophilic amoebocytes, acidophilic granulocytes arthropod immune systems
SHN-1 Human Digestive Panel Test results
SHN-1 Human Digestive Panel Test results HN-30 tongue HN-24 salivary gland HN-12 larynx HN-28 esophagus HN-29 stomach HN-20 pancreas HN-13 liver HN-14 gall bladder HN-27-1 duodenum HN-27-2 ileum HN-27-3
Tumor Markers & Cytopathology
Tumor Markers & Cytopathology Objectives: After learning, student should be able to 1. Describe the basic concepts of tumor markers and Asst. Prof. Prasit Suwannalert, Ph.D. (Email: prasit.suw@mahidol.ac.th)
The Lymphatic System and Body Defenses
PowerPoint Lecture Slide Presentation by Patty Bostwick-Taylor, Florence-Darlington Technical College The Lymphatic System and Body Defenses 12PART B Adaptive Defense System: Third Line of Defense Immune
C-reactive protein. An ED perspective Greg Stevens May 2010
C-reactive protein An ED perspective Greg Stevens May 2010 Basic Biology Is a short Pentraxin Penta 5, ragos berries 224 residue protein 25106 Da Gene 1q21-q23 q23 History Tillett WS, Francis T Jr. Serological
Neoplasia 2018 lecture 11. Dr H Awad FRCPath
Neoplasia 2018 lecture 11 Dr H Awad FRCPath Clinical aspects of neoplasia Tumors affect patients by: 1. their location 2. hormonal secretions 3. paraneoplastic syndromes 4. cachexia Tumor location Even
AVAILABLE BIOMARKER ASSAYS
AAILABLE BIOMARKER ASSAYS alidation Alpha-2-microglobulin ELISA Anti-CD71/anti-platelet/propidium iodide Anti-KLH IgG ELISA,, Dog, Minipig, Apoptotic, necrotic and dead cells (bone marrow) B (activated
List of Available TMAs in the PRN
TMA RPCI_BrainCa01 RPCI_BrCa03 RPCI_BrCa04 RPCI_BrCa05 RPCI_BrCa0 RPCI_BrCa07 RPCI_BrCa08 RPCI_BrCa15 RPCI_BrCa1 RPCI_BrCa17 RPCI_BrCa18 RPCI_BrCa19 RPCI_BrCa20 RPCI_BrCa21 RPCI_BrCa24 RPCI_BrCa25 RPCI_BrCa2
Immune System AP SBI4UP
Immune System AP SBI4UP TYPES OF IMMUNITY INNATE IMMUNITY ACQUIRED IMMUNITY EXTERNAL DEFENCES INTERNAL DEFENCES HUMORAL RESPONSE Skin Phagocytic Cells CELL- MEDIATED RESPONSE Mucus layer Antimicrobial
Liver Cancer. Su Jong Yu, M.D. Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine
Liver Cancer Su Jong Yu, M.D. Department of Internal Medicine, Liver Research Institute, Seoul National University College of Medicine Primary Liver Cancer Hepatocellular carcinoma (HCC) : > 80% Derived
Blood. Biol 105 Lecture 14 Chapter 11
Blood Biol 105 Lecture 14 Chapter 11 Outline I. Overview of blood II. Functions of blood III. Composition of blood IV. Composition of plasma V. Composition of formed elements VI. Platelets VII. White blood
Minimum Whole Blood Volumes for Microcollection Tubes for Neonates, Pediatrics, Patients less than 45 kg (100 lb) and Difficult Collections
The following table outlines the minimum whole blood volume that must be drawn into a microcollection tube (unless otherwise stated) for an individual test on a neonate, pediatric, patient weighing less
Molecular and Cellular Basis of Immune Protection of Mucosal Surfaces
Molecular and Cellular Basis of Immune Protection of Mucosal Surfaces Department of Biologic & Materials Sciences School of Dentistry University of Michigan Ann Arbor, Michigan 48109-1078 1 Image quality
Basic Immunology. Lecture 26 th. Immunity against tumors
Basic Immunology Lecture 26 th Immunity against tumors Neoplastic transformations are genetic alterations. Expression of cell surface antigens both self and non-self - seen by immune system. Ehrlich positive
Chapter 21: Innate and Adaptive Body Defenses
Chapter 21: Innate and Adaptive Body Defenses I. 2 main types of body defenses A. Innate (nonspecific) defense: not to a specific microorganism or substance B. Adaptive (specific) defense: immunity to
Physiology Unit 3. ADAPTIVE IMMUNITY The Specific Immune Response
Physiology Unit 3 ADAPTIVE IMMUNITY The Specific Immune Response In Physiology Today The Adaptive Arm of the Immune System Specific Immune Response Internal defense against a specific pathogen Acquired
Overview of the Lymphoid System
Overview of the Lymphoid System The Lymphoid System Protects us against disease Lymphoid system cells respond to Environmental pathogens Toxins Abnormal body cells, such as cancers Overview of the Lymphoid
HEPETIC SYSTEMS BIOCHEMICAL HEPATOCYTIC SYSTEM HEPATOBILIARY SYSTEM RETICULOENDOTHELIAL SYSTEM
EVALUATION OF LIVER FUNCTION R. Mohammadi Biochemist (Ph.D.) Faculty member of Medical Faculty HEPETIC SYSTEMS BIOCHEMICAL HEPATOCYTIC SYSTEM HEPATOBILIARY SYSTEM RETICULOENDOTHELIAL SYSTEM METABOLIC FUNCTION
Blood and Immune system Acquired Immunity
Blood and Immune system Acquired Immunity Immunity Acquired (Adaptive) Immunity Defensive mechanisms include : 1) Innate immunity (Natural or Non specific) 2) Acquired immunity (Adaptive or Specific) Cell-mediated
Foundations in Microbiology
Foundations in Microbiology Fifth Edition Talaro Chapter 15 The Acquisition of Specific Immunity and Its Applications Chapter 15 2 Chapter Overview 1. Development of the Dual Lymphocyte System 2. Entrance
Diseases-causing agents, pathogens, can produce infections within the body.
BIO 212: ANATOMY & PHYSIOLOGY II 1 CHAPTER 16 Lecture: Dr. Lawrence G. Altman www.lawrencegaltman.com Some illustrations are courtesy of McGraw-Hill. LYMPHATIC and IMMUNE Systems Body Defenses Against
Alpha-fetoprotein
Other Names/Abbreviations AFP 190.25 - Alpha-fetoprotein Alpha-fetoprotein (AFP) is a polysaccharide found in some carcinomas. It is effective as a biochemical marker for monitoring the response of certain
T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes:
Interactions between innate immunity & adaptive immunity What happens to T cells after they leave the thymus? Naïve T cells exit the thymus and enter the bloodstream. If they remain in the bloodstream,
T-cell activation T cells migrate to secondary lymphoid tissues where they interact with antigen, antigen-presenting cells, and other lymphocytes:
Interactions between innate immunity & adaptive immunity What happens to T cells after they leave the thymus? Naïve T cells exit the thymus and enter the bloodstream. If they remain in the bloodstream,
Liver Disease. By: Michael Martins
Liver Disease By: Michael Martins Recently I have been getting a flurry of patients that have some serious liver complications. This week s literature review will be the dental management of the patients
Alpha-fetoprotein
Other Names/Abbreviations AFP 190.25 - Alpha-fetoprotein Alpha-fetoprotein (AFP) is a polysaccharide found in some carcinomas. It is effective as a biochemical marker for monitoring the response of certain
Alpha-fetoprotein
Other Names/Abbreviations AFP 190.25 - Alpha-fetoprotein Alpha-fetoprotein (AFP) is a polysaccharide found in some carcinomas. It is effective as a biochemical marker for monitoring the response of certain
The Immune System: Innate and Adaptive Body Defenses Outline PART 1: INNATE DEFENSES 21.1 Surface barriers act as the first line of defense to keep
The Immune System: Innate and Adaptive Body Defenses Outline PART 1: INNATE DEFENSES 21.1 Surface barriers act as the first line of defense to keep invaders out of the body (pp. 772 773; Fig. 21.1; Table
Specific Panels. Celiac disease panel. Pancreas Panel:
Specific Panels Celiac disease panel Anti Endomysium IgA Anti Endomysium IgG Anti Gliadin IgA Anti Gliadin IgG Anti Transglutaminase IgA Anti Transglutaminase IgG Total IgA Total IgG Stool analysis +Sudan
Immune surveillance hypothesis (Macfarlane Burnet, 1950s)
TUMOR-IMMUNITÄT A.K. Abbas, A.H. Lichtman, S. Pillai (6th edition, 2007) Cellular and Molecular Immunology Saunders Elsevier Chapter 17, immunity to tumors Immune surveillance hypothesis (Macfarlane Burnet,
Hepatogenesis I Liver development
Hepatogenesis I Liver development HB 308 George Yeoh Room 2.59 MCS Building yeoh@cyllene.uwa.edu.au Topics Early liver development Tissue interaction - role of morphogens and cytokines Liver enriched transcription
What are the functions of blood?
What are the functions of blood? Transportation: oxygen, nutrients, wastes, carbon dioxide, nitrogen from amino acids and hormones, lipoproteins HDL and LDL Hemoglobin carries oxygen and CO2, (CO poisoning)
Chapter 17B: Adaptive Immunity Part II
Chapter 17B: Adaptive Immunity Part II 1. Cell-Mediated Immune Response 2. Humoral Immune Response 3. Antibodies 1. The Cell-Mediated Immune Response Basic Steps of Cell-Mediated IR 1 2a CD4 + MHC cl.
Please check the slides
Quick review of main concepts: The major plasma proteins are : albumin, globulin and fibrenogen globulin consists of 3 types: α, β and γ α globulin is divided into 2 types : α1 (includes α1 antitrypsin
PLASMA PROTIENS. 3)What are the plasma proteins,their functions generally and specifically and processes associated with these proteins?
1 PLASMA PROTIENS Refer to slide #1 * Goals from these 2 lectures: 1)What is the plasma? How can we get it? 2)What are the different components of the plasma? 3)What are the plasma proteins,their functions
AP Biology. Why an immune system? Chapter 43. Immune System. Lines of defense. 1st: External defense. 2nd: Internal, broad range patrol
Chapter 43. Immune System lymphocytes attacking cancer cell lymph phagocytic leukocyte Why an immune system? Attack from outside lots of organisms want you for lunch! animals must defend themselves against
Principles of Adaptive Immunity
Principles of Adaptive Immunity Chapter 3 Parham Hans de Haard 17 th of May 2010 Agenda Recognition molecules of adaptive immune system Features adaptive immune system Immunoglobulins and T-cell receptors
Laboratory diagnosis of plasma proteins and plasma enzymes
Laboratory diagnosis of plasma proteins and plasma enzymes Functions of plasma proteins Function: transport humoral immunity enzymes protease inhibitors maintenance of oncotic pressure buffering Example:
Panel of Rat cell lines
Panel of Rat cell s Part of the CLS cell bank CLS Cell Lines Service Table 1: Rat cell s: Origin and General Characteristics Name of cell Cell type Organism, Ethnicity Age / Gender Tissue / Disease Morphology
Cancers of unknown primary : Knowing the unknown. Prof. Ahmed Hossain Professor of Medicine SSMC
Cancers of unknown primary : Knowing the unknown Prof. Ahmed Hossain Professor of Medicine SSMC Definition Cancers of unknown primary site (CUPs) Represent a heterogeneous group of metastatic tumours,
Introduction to Immunology and the Immune System
Introduction to Immunology and the Immune System Assistant professor Dr. Aida R. Al-Derzi M.B.Ch.B; M.Sc; FICM/Path Dept. of Microbiology/College of Medicine/Baghdad University Introduction to Immunology
1ME A17R11 WI238 DMS2114 JC L2929 P815 PT67
20 1 2004 1 Chinese Journal of Biotechnology Vol. 20 No. 1 January 2004 3 (, 361005), BacV2CMV2EGFPA,Sf9, 20, 12,7,1 CMV,,,LipofectAMINE CMV EGFP pcdna3112egfp, CMV EGFP, CMV CMV,,,,,, Bac2to2Bac 2, CMV,,,
Genetic Alteration Panels
TM Genetic Alteration Panels GENETIC ALTERATION PANELS Table of Contents AKT Genetic Alteration Panel (ATCC No. TCP-1029 )...1 BRAF Genetic Alteration Panel (ATCC No. TCP-1032 )...5 EGFR Genetic Alteration
4/5/17. Blood. Blood. Outline. Blood: An Overview. Functions of Blood
Outline Blood Biol 105 Chapter 11 I. Overview of blood II. Functions of blood III. Composition of blood IV. Composition of plasma V. Composition of formed elements VI. Platelets VII. White blood cells
Technology from Abcam
CD2 (EP222) CD2 is one of the earliest T-cell lineage restricted antigens to appear during T-cell differentiation and only rare CD2+ cells can be found in the bone marrow. Anti-CD2 is a pan-t-cell antigen
LYMPHOCYTES & IMMUNOGLOBULINS. Dr Mere Kende, Lecturer SMHS
LYMPHOCYTES & IMMUNOGLOBULINS Dr Mere Kende, Lecturer SMHS Immunity Immune- protection against dangers of non-self/invader eg organism 3 components of immune system 1 st line: skin/mucosa/cilia/hair/saliva/fatty
Human cell line list Production of Exosome Standards - Cell Lysates
Human cell line list 2016 - Production of Exosome Standards - Cell Lysates 380 peripheral blood leukemia, pre-b cell 1301 blood leukemia, acute lymphoblastic, T cell 5637 bladder carcinoma 8305C thyroid
25 years of research excelence
Crystal Chem full product catalog 25 years of research excelence We're poud to be one of the top providers of research assays for the last 25 years product catalog See our full line of high quality assays
Chapter 13. Plasma Proteins and Enzymes. Lecturer: Dr Abeer Shnoudeh. Clinical Chemistry William Marshall
Chapter 13 Plasma Proteins and Enzymes Lecturer: Dr Abeer Shnoudeh Clinical Chemistry William Marshall Introduction Measurement of Plasma Proteins Total Plasma Protein concentration of total protein in
Cancer Biology Course. Invasion and Metastasis
Cancer Biology Course Invasion and Metastasis 2016 Lu-Hai Wang NHRI Cancer metastasis Major problem: main reason for killing cancer patients, without it cancer can be cured or controlled. Challenging questions:
The Adaptive Immune Response. T-cells
The Adaptive Immune Response T-cells T Lymphocytes T lymphocytes develop from precursors in the thymus. Mature T cells are found in the blood, where they constitute 60% to 70% of lymphocytes, and in T-cell
Ch. 45 Blood Plasma proteins, Coagulation and Fibrinolysis Student Learning Outcomes: Describe basic components of plasma
Chapt. 45 Ch. 45 Blood Plasma proteins, Coagulation and Fibrinolysis Student Learning Outcomes: Describe basic components of plasma Inheritance of X-linked gene for Factor VIII hemophilia A Explain the
CERTIFICATE OF ACCREDITATION
CERTIFICATE OF ACCREDITATION LANCET KENYA LIMITED UPPERHILL NAIROBI LABORATORY Co. Reg. No.: C168507 Facility Accreditation Number: is a South African National Accreditation System accredited laboratory
Internal Defense Notes
Internal environment of animals provides attractive area for growth of bacteria, viruses, fungi Harm via: 1. destruction of cells 2. production of toxic chemicals To protect against foreign invaders, humans
Neoplasias Quisticas del Páncreas
SEAP -Aproximación Práctica a la Patología Gastrointestinal- Madrid, 26 de mayo, 2006 Neoplasias Quisticas del Páncreas Gregory Y. Lauwers, M.D. Director, Service Massachusetts General Hospital Harvard
IMMUNITY AND DISEASE II
IMMUNITY AND DISEASE II A. Evolution of the immune system. 1. Figure 1--57.25, p. 1167 from Raven and Johnson Biology 6 th ed. shows how the immune system evolved. Figure 1. How the immune system evolved.
The Immune System. These are classified as the Innate and Adaptive Immune Responses. Innate Immunity
The Immune System Biological mechanisms that defend an organism must be 1. triggered by a stimulus upon injury or pathogen attack 2. able to counteract the injury or invasion 3. able to recognise foreign
1. Overview of Adaptive Immunity
Chapter 17A: Adaptive Immunity Part I 1. Overview of Adaptive Immunity 2. T and B Cell Production 3. Antigens & Antigen Presentation 4. Helper T cells 1. Overview of Adaptive Immunity The Nature of Adaptive
The Panel Approach to Diagnostics. Lauren Hopson International Product Specialist Cell Marque Corporation
The Panel Approach to Diagnostics Lauren Hopson International Product Specialist Cell Marque Corporation Cell Marque Rocklin, California About Cell Marque: IVD primary antibody manufacturer Distributors
The Digestive System. What is the advantage of a one-way gut? If you swallow something, is it really inside you?
The Digestive System What is the advantage of a one-way gut?! If you swallow something, is it really inside you? Functions and Processes of the Digestive System: Move nutrients, water, electrolytes from
LECTURE: 21. Title IMMUNOGLOBULINS FUNCTIONS & THEIR RECEPTORS LEARNING OBJECTIVES:
LECTURE: 21 Title IMMUNOGLOBULINS FUNCTIONS & THEIR RECEPTORS LEARNING OBJECTIVES: The student should be able to: Determine predominant immunoglobulin isotypes in serum. Determine the predominant immunoglobulin
Whole Blood. Lab 29A. Blood. Plasma. Whole Blood. Formed Elements. Plasma: Fluid component. Formed elements: Cells and fragments
Whole Blood Lab 29A. Blood Plasma: Fluid component Water (90%) Dissolved plasma proteins Other solutes Formed elements: Cells and fragments RBCs (carry Oxygen) WBCs (immunity) Platelets (cell fragments
Chapter 9 The Endocrine System and Hormone Activity
Chapter 9 The Endocrine System and Hormone Activity Overview Coordinates and directs the activity of cells. Interacts with the nervous system Uses chemical messengers called hormones released by organs
BIO 116 Practice Assignment 1 The Endocrine System and Blood This is not a required assignment but it is recommended.
BIO 116 Practice Assignment 1 The Endocrine System and Blood This is not a required assignment but it is recommended. 1. Match the following glands of the endocrine system with the appropriate label 1.
28. Bilirubin (total, total conjugated, unconjugated, direct and indirect).
1. 17-OH-Progesterone. 2. 5α-dihydrotestosterone (DHT). 3. Adrenocorticotropic Hormone ACTH. 4. Alanine Transaminase (ALT, SGPT). 5. Albumin, qualitative. 6. Aldosterone. 7. Allergen Specific IgG Antibody.
Adaptive Immunity: Humoral Immune Responses
MICR2209 Adaptive Immunity: Humoral Immune Responses Dr Allison Imrie 1 Synopsis: In this lecture we will review the different mechanisms which constitute the humoral immune response, and examine the antibody
Turbidos. Design Verification. Contents
Design Verification Turbidos Contents 1 adjustment... 2 2 Target value determination... 2 3 Stability... 2 3.1 Accelerated stress data... 2 3.2 Open vial stability... 3 3.3 Real Time Stability... 4 4 Result
GMI STUDY. COMPARATIVE PROTEOMIC STUDY BETWEEN GMI and STRAUMANN DENTAL IMPLANTS
GMI STUDY. COMPARATIVE PROTEOMIC STUDY BETWEEN GMI and STRAUMANN DENTAL IMPLANTS 2 Hypothesis. Proteomic study of first protein layer Post-implantation, the biomaterial becomes in contact with the blood,
Anatomy and Physiology. The Endocrine System
Anatomy and Physiology The Endocrine System The endocrine system includes anything that secretes hormones directly into body fluids. Endocrine glands include: the thyroid, parathyroid, adrenal, kidney,
Allergy and Immunology Review Corner: Chapter 19 of Immunology IV: Clinical Applications in Health and Disease, by Joseph A. Bellanti, MD.
Allergy and Immunology Review Corner: Chapter 19 of Immunology IV: Clinical Applications in Health and Disease, by Joseph A. Bellanti, MD. Chapter 19: Tolerance, Autoimmunity, and Autoinflammation Prepared
Research Article Stromal Expression of CD10 in Invasive Breast Carcinoma and Its Correlation with ER, PR, HER2-neu, and Ki67
SAGE-Hindawi Access to Research International Breast Cancer Volume 20, Article ID 47957, 4 pages doi:0.406/20/47957 Research Article Stromal Expression of CD0 in Invasive Breast Carcinoma and Its Correlation
Ig light chain rearrangement: Rescue pathway
B Cell Development Ig light chain rearrangement: Rescue pathway There is only a 1:3 chance of the join between the V and J region being in frame Vk Jk Ck Non-productive Rearrangement Light chain has a
In 2008 NICE issued guidelines on lipid modification. Key points are summarised below.
Hyperlipidaemia: management In 2008 NICE issued guidelines on lipid modification. Key points are summarised below. Primary prevention A systematic strategy should be used to identify people aged 40-74
Innate immunity (rapid response) Dendritic cell. Macrophage. Natural killer cell. Complement protein. Neutrophil
1 The immune system The immune response The immune system comprises two arms functioning cooperatively to provide a comprehensive protective response: the innate and the adaptive immune system. The innate
NEW IHC A n t i b o d i e s
NEW IHC Antibodies TABLE OF CONTENTS NEW IHC ANTIBODIES from Cell Marque CITED1 (5H6).... 1 Claudin 7 (5D10F3).... 1 GATA1 (4F5).... 1 Transgelin (2A10C2).... 1 NEW IHC ANTIBODIES using RabMAb Technology
Antibody-Cytokine- Autoimmune
Antibody-Cytokine- Autoimmune Surasak Wongratanacheewin, Ph.D Dean, Graduate School, KKU Microbiology, Faculty of Medicine, KKU sura_wng@kku.ac.th การอบรมหล กส ตรประกาศน ยบ ตรการข นทะเบ ยนช วว ตถ ว นท
Microarray Analysis and Liver Diseases
Microarray Analysis and Liver Diseases Snorri S. Thorgeirsson M.D., Ph.D. Laboratory of Experimental Carcinogenesis Center for Cancer Research, NCI, NIH Application of Microarrays to Cancer Research Identifying
Antigen-Independent B-Cell Development Bone Marrow
Antigen-Independent B-Cell Development Bone Marrow 1. DNA rearrangements establish the primary repertoire, creating diversity 2. Allelic exclusion ensures that each clone expresses a single antibody on
8 years later! Next Generation Sequencing. Pathogenic Findings: HNF1A c.864delinscc, p.g292rfs*25 (NM_ ) (VAF: 59%) HNF1A Loss
8 years later! Next Generation Sequencing Pathogenic Findings: HNF1A c.864delinscc, p.g292rfs*25 (NM_000545.6) (VAF: 59%) HNF1A Loss Interpretation HNF1A c.864delinscc, p.g292rfs*25 (NM_000545.6) This
Cell-Derived Inflammatory Mediators
Cell-Derived Inflammatory Mediators Introduction about chemical mediators in inflammation Mediators may be Cellular mediators cell-produced or cell-secreted derived from circulating inactive precursors,
Immune response. This overview figure summarizes simply how our body responds to foreign molecules that enter to it.
Immune response This overview figure summarizes simply how our body responds to foreign molecules that enter to it. It s highly recommended to watch Dr Najeeb s lecture that s titled T Helper cells and
CERTIFICATE OF ACCREDITATION
CERTIFICATE OF ACCREDITATION In terms of section 22(2) (b) of the Accreditation for Conformity Assessment, Calibration and Good Laboratory Practice Act, 2006 (Act 19 of 2006), read with sections 23(1),