POSTER SESSIONS--COMBINED SCIENCE COMBINED SCIENCE

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1 POSTR SSSIONS--COMBIN SCINC COMBIN SCINC AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F Modal Convention Center AUTOIMMUN LIVR ISAS AN HPATIC IMMUNOLOGY M1977 M1978 M1979 M1980 M1981 M1982 M1983 M1984 M1985 M1986 Progressive Fibrosis in Autoimmune Hepatitis espite Corticosteroid Therapy: Frequency and Predisposing Factors Albert J. Czaja, Herschel A. Carpenter Nonstandard Autoantibodies as Prognostic Markers in Autoimmuue Hepatitis Albert J. Czaja, Zakera Shums, Gary L. Norman Clinical and Histologic Features in Patients with Acute Autoimmune Hepatitis William R. Kessler, Naga Chalasani, Oscar W. Cummings, Lawrence Lumeng, George ckert, Paul Y. Kwo arly Treatment Response Predicts the Need for Liver Tranplantation in Autoimmune Hepatitis P. Tan, Cam Ghent, Paul Marotta, P. Adams Factors Predicting Relapse/Poor Outcome in Type 1 Autoimmune Hepatitis: Role of Cirrhosis evelopment, Patterns of Transaminases uring Remission and Plasma Cell Activity Sumita Verma, Basuki Gunawan, Michel Mendler, Sugantha Govindrajan, Allan Redeker Transplant Immunosuppressive Agents in Non- Transplant Chronic Autoimmune Hepatitis: The CASL xperience with Mycophenolate Mofetil and Tacrolimus Nazira Chatur, Alnoor Ramji, Vince Bain, Mang Ma, Paul Marotta, Cam Ghent, Leslie Lilly, Jenny Heathcote, Marc eschenes, Urs Steinbrecher, ric Yosbida Biochemical, Immunological and HLA Gene ifferences Between Autoimmune Liver iseases and Hepatic Overlap Syndromes Sergio Zepeda-Gomez, Juan Carlos Zapata-Colindres, Octavio Gomez-scudero, Angelica Rodriguez-Carreon, Francisco Pax, Julio Granados, Marco Antonio Olivera- Martinez Frequency and Significance of Antibodies to Saccharomyces cerevisiae in Autoimmune Hepatitis: Clues to Concurrent Mucosal isease? Albert J. Czaja, Zakera Shums, Peter T. onaldson, Gary L. Norman CXCR6 Mediates Recruitment of C8 Lymphocytes to Inflamed Liver Tohru Sato, Henrik Thorlacius, Brent Johnston, Wenkai Xiang, an R. Littman, ugene C. Butcher High Affinity Antigen eletion of Hepatic T Cells Is ependent on Kupffer Cells Yuhshi Kuniyasu, Suhail Marfani, Irteza Inayat, Shehzad Sheikh, Wajahat Mehal AASL Poster Session AM-5:00 PM Hall F Modal Convention Center CLINICAL AN XPRIMNTAL HPATOBILIARY CANCR M1987 M1988 M1989 M1990 M1991 M1992 M1993 M1994 M1995 M1996 Functional xpression of TWAK in Human Hepatocellular Carcinoma Tomoyuki Kawakita, Katsuya Shiraki, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Naoyuki nokimura, Norihiko Yamamoto, Hiroshi Okano, Kazushi Sugimoto, Kazumoto Murata, Takeshi Nakano PPAR-Alpha L162V Polymorphism in Human Hepatocellular Carcinoma lif S. Koytak, Hasibe Verdi, Filiz Akbiyik, Ayca A. rgul, Ramazan Idilman, Kubilay Cinar, Mithat Bozdayi, Cihan Yurdaydin, Ozden Uzunalimoglu, Hakan Bozkaya Pyrimidine Nucleoside Phosphorylase (PyNPase) Activity in the Liver Tissue of Patient with Hepatocellular Carcinoma lkuo Nagashima, Tadahiro Takada, Hisae Inuma, Kota Okinaga High Nociceptin Content in Human Hepatocellular Carcinoma Tissue Andrea Horvath, Aniko Folhoffer, Timea Csak, Peter L. Lakatos, Monika B. Hantos, Kornelia Tekes, Attila Szijarto, Peter Kupcsulik, Andras Kiss, Judit Halasz, Zsuzsa Schaff, Ferenc Szalay Influence of Large Intrahepatic Blood Vessels on Gross and Histological Characteristic of Lesions Generated by Radiofrequency Ablation in a Pig Liver Model Katsuyoshi Tamaki, Ichiro Shimizu, Hiroshi Shibata, Man Urata, Atsuo Ooshio, Hiroshi Fukuno, Akemi Tsutsui, Susumu Ito Suppressive ffect of Menatetrenone, a Vitamin K2 Analog, on Recurrence of Hepatocellular Carcinoma Improved Patient Survival Toshihiko Mizuta, Iwata Ozaki, Kyosuke Yamaluoto, Kazuma Fu]imoto Recurrence of Hepatocellular Carcinoma After Curati'~c Ablation Therapy Haruhiko Yoshida, Ryosuke Tateishi, Shuichiro Shima. Tomonori Fujishima, Masatoshi Akamat>u, Shuntato Obj. Shinpei Sato, Takuma Teratani, Takao Kawabe, Macao Omata Radiofrequency Ablation Combined with Transcadlcler Arterial Chemoembolization for Small Hepatocelhdar Carcinomas Hiroshi Aikata, Shintaro Yakaki, Shutetsu Tci, Hivoto Ishihara, Shoichi Takahashi, Ka:uaki Chayama Artificial Ascites Using a Special Needle to Avoid GI Tract Perforation in Radiofrequency Ablation (RFA) for Liver Tumors Shuicbiro Shiina, Takuma Teratani, Shinpei Sato, Ryosuke Tateishi, Tomonori Fujishima, Takashi Ishikawa, Yuji Kondo, Noriyo Yamashiki, Norio Mine, Miho Kanda, Shuntaro Obi, Masatoshi Akamatsu, Hideo Yoshida, Yukihiro Koike, Masatoshi Imamura, Keisuke Hamamura, Haruhiko Yoshida, Takao Kawabe, Masao Omata Prognostic Factors Associated with Treatment Response to Octreotide in Advanced Hepatocellular Cancer (HCC) Gerhard G. Treiber, Thomas Wex, Christoph Roecken, Peter Malfertheiner enotes W Poster of istinction P-195

2 POSTR SSSIONS--COMBIN SCINC M1997 Hepatic Arterial Infusion Chemotherapy Prolonged Survival of Patients with Advanced Hepatocellular M2010 Carcinomas Ryota Masuzaki, Seiji Kawazoe, Hirohisa Shigematsu, Kyosuke Yamamoto, Kazuma Fnjimoto Idiopathic Fibrosing Biliary Strictures in Surgical Resected Patients with Presumed Cholangiocarcinoma: Clinical Comparison with Cholangiocarcinoma Harshad evabhavi, avid Nagorney, Michael Farnell, John onohue, Linda Stadheim, Gregory J. Gores M1998 M1999 Radiofrequency Ablation Following Selective Arterial mbolization for Hepatocellular Cancer; a Trial to M2011 Reduce the Tumor Volume Prior to Ablation Keisuke Hamamura, Naofumi Shirane, Hiroaki Fukuzawa, Kazunori Matsumura, Yoshihisa Tsukioka, Hideyuki Kin, Koichi Kojima M2012 Local Therapeutic Results of Computed Tomographyguided Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Single Application for 270 Tumors in 80 Patients M2013 Keiji Hayashi, Hiroyasu Ina, Mikio Tezuka, Yoichi Okada, Tetsuya lrie Most Primary Lymphomas of the Liver Are iffuse Large B Cell Lymphomas Michael Torbenson, dward Weir, Susan Abraham Premalignant isease Characterization in a Mouse Model of Infectious Liver Cancer Arlin B. Rogers, Mark T. Whary, Nataliya Sundina, Samuel R. Boutin, James G. Fox Liver Cell Proliferation Induced by Tri-Iodothyronine Is Associated with an Up-Regulation of the Bcl-3 Proto- Oncogene Raza Malik, avid Brown, Humphrey Hodgson r M O N A Y MAY 17 M2000 M2001 M2002 M2003 M2004 M2005 M2006 M2007 M2008 M2009 Historical Pilot Trail for valuation of Percutaneous Radiofrequency Ablation Therapy in Patients with M2014 Hepatocellular Carcinomas Compared to Percutaneous thanol Injection Therapy Seiji Kawazoe, Ryota Masuzaki, Hirohisa Shigematsu, Kyosuke Yamamoto, Kazuma Fujimoto Chemoembolization Therapy of Hepatocellular Cancer - Results of Selective mbolization Therapy in 112 Patients Alan A. Weiss, Stephen Ho, Peter Munk, Stephen Chung, Charles Scudamore, Chuck Paltiel Results of a Pilot Study with Octreotide for Patients with Hepatocellular Carcinoma Linda M. Stadheim, Ziad M. Hassoun, Ugochukwu C. Nzeako, K. V. Narayanan Menon, Jayant A. Talwalkar, Nicholas F. LaRusso, Gregory J. Gores Management of Brain Metastasis of Hepatocellular Carcinoma Jamy Yong, Mei Yee Leung, Chi Ming Lam, Sheung Tat Fan M2015 M2016 Percutaneous Ultrasound-guided Radiofrequency Ablation with the Artificial Pleural ffusion for Hepatocellular Carcinoma in the Hepatic ome Yasunori Minami, Masatoshi Kudo, Toshihiko Kawasaki, M2017 Hobyung Chung, Chikara Ogawa, Tatsuo Inoue, Yasuhiro Sakaguchi, Hiroki Sakamoto, Hitoshi Shiozaki Radiofrequency Ablation (RFA) for lderly Patients with Hepatocellular Carcinoma (HCC) Takuma Teratani, Shuichiro Shiina, Shinpei Sato, Shuntaro Obi, Masatoshi Akamatsu, Tomonori Fujishima, Ryosuke Tateishi, Miho Kanda, Noriyo Yamashiki, Norio Mine, Yuji M2018 Kondo, Haruhiko Yoshida, Takashi Ishikawa, Haruhiko Yoshida, Takao Kawabe, Masao Omata The Assessement by Using Multiditecter-row CT in the Treatment of Hepatocellular Carcinoma with Radiofrequency Thermal Ablation ' Shintaro Takaki, Hiroshi Aikata, Shutetsu Tel, Hiroto M2019 Ishihara, Shoichi Takahashi, Kazuaki Chayama The ffect of ML on Liver Transplantation for Hepatocellular Carcinoma Julie M Winn, Karl T. srason Stage ependent Therapeutic Strategies and Results for 180 Patients with Hilar Cholangiocarcinoma Marcus Wiedmann, Uli Ringel, Hubert Witzigmann, Frieder Berr, Johann Hauss, Joachim Moessner, Karel Caca Activation of Proinflammatory Cytokines by Photodynamic Therapy in Cholangiocellular Carcinoma Juergen Bauditz, Maria-Anna Ortner, Andreas Giese, Herbert Lochs M2020 Chronological Gene xpression Profiling in the Premalignant Phase of a Mouse Model of Infectious Liver Cancer Samuel R. Boutin, Arlin B. Rogers, Zeli Shen, Jennifer A. Love, Rebecca C. Fry, James G. Fox Inflammatory Cell Populations uring Hepatic Carcinogenesis Lisa M. Yerian, Robert A. Anders, Mark W. Lingen, John Hart AASL Poster Session AM-5:00 PM Hall F Mot-ial Convention Center HPATITIS C: IAGNOSIS AN NATURAL HISTORY Novel Hepatitis C Virus Genotyping Method Based on Mass Spectrometric Analysis of Oligonucleotide Fragments Yun Joon Kim, Hyun J. Chung, Mi Sun Ji, Kang M. Kim, Jung-Hwan Yoon, Byeong G. Kim, Hyo-Suk Lee, Chung Y. Kim, Soo-Ok Kim, Wangdon Yoo, Sun P. Hong HCV Core Quasispecies Change Is Associated with nd Stage Liver isease in a Longitudinal Cohort of HCV and HCV/I-I1V Infected Patients with Inherited Bleeding isorders Hongxing Qin, Norah J. Shire, Susan. Rouster, M.. yster, James J. Goedert, Margaret J. Koziel, Kenneth. Sherman Fibrosis Progression Is ependent upon Hepatic Inflammation in Patients with Chronic HCV Joon Mo Myung, Iliana Bouneva, Jennifer Salvatori, Melissa J. Contos, Mitchell L. Shiffman, Richard K. Sterling, R. Todd Stravitz, Velimir A. Luketic, Andrea Ferreira- Gonzalez, A. S. Mills, Arun J. Sanyal The Interleukiu-10 Receptor 1 (IL-10R1) G330R Allele Is Associated with Advanced Fibrosis in Chronic HCV-1 Infection Harald Hofer, Julius B. Neufeld, Christoph Oesterreicher, Paul Grundmer, Fritz Wrba, Peter Ferenci, Christoph Gasche High Prevalence of Novel Genotypes in Vietnamese Patients with Chronic Hepatitis C Mindie H. Nguyen, Huy Trinh, Ruel T. Garcia, Jing Ning, mmet Keeffe Natural History of Acute Hepatitis C in a U.S. Cohort M2021 Andrew Ross, Raymond T. Chung P enotes W Poster of istinction

3 POSTR SSSIONS~COMBIN SCINC M2022 M2023 M2024 M2025 M2026 M2027 M2028 M2029 M2030 M2031 M2032 M2033 M2034 Proposal and Validation of the AST/ALT Ratio for Predicting the Presence of Significant Fibrosis in M2035 Patients with Chronic Hepatitis C doardo Giannini, Luca Mastracci, Paola Ceppa, Roberto Testa A Comparative Study on Natural History of Chronic M2036 Hepatitis C in Patients with Chronic Renal Failure (CRF) vs. Normal Renal Function (NRF) Ke-Qin Hu, Steve Lee, Namgyal k. Kyulo, Victor W. Xia, onald J. Hillebrand, Shirley X. Hu, Chang-Hong Yu M2037 HCV RNA etection in Catrimox-14 Whole Blood and Plasma Keynr Patel, Jeff Albrecht, Anouk ev, rin Owens, Shanon Heaton, Andrew Muir, Stephen Pianko, Paul J. Pockros, Andrew Conrad, Lawrence Blatt, John G. McHutchison M2038 Stellate Cell Activation and Fibrosis Progression in Recurrent Hepatitis C After Liver Transplantation Sripriya Balasubramanian, Christopher k Bowlus, Rajendra Ramsamooj, Byung K. Minh, Boris Ruebner, Lorenzo M2039 Rossaro Aminopyrine and Methacetin 13C-Breath Tests to Assess Hepatic Function in HCV-Related Chronic Liver isease nrico C. Nista, Immacolata A. Cazzato, Alessandro Armuzzi, Lucia Fini, Marcello Candelli, Maria A. Zocco, Lorenzo Zileri al Verme, Rosalba Finizio, Giovanni Gasbarrini, Antonio Gasbarrini oes Non-Alcoholic Fatty Liver isease (NAFL) and Its Risk Factors Affect the Progression of Fibrosis in HCV Patients? Joel Kertznus, Arie Regev, nrique Molina, Jonatan Konfino, Patricia Mendez, Adriana Arcila, ugene Schiff M2040 IN valuation of the isease Progression of Chronic 8 Hepatitis C by the Score efined by Platelet Count and Alubumin Level Kohsaku Sakaguchi, Akiko Fujiwara, Shin-Ichi Fujioka, Yasushi Shiratori A Validated Noninvasive Prsd, icl~llj~f Liver Fibrosis in M2041 Chronic Hepatit~C~ ~12~1~ ]~'~ Leon/~t~a,~O~.~, l~n~co Rossi, Bastiaan 8 I3~r~o[ ~el~rrge, Geoff Farrell, Geoffrey McCaughan, Ga~lN/~."Jeffrey The Clinical Utility of HCV RNA etection in Catrimox- M Whole Blood uring Therapy Keyur Patel, Jeff Albrecht, rin Owens, Anouk ev, Shanon Heaton, Andrew J. Muir, Stephen Pianko, Paul J. Pockros, Andrew Conrad, Lawrence Blatt, John G. McHutchison 13C-Aminopyrine Breath Test in Alcoholic and Virus C Related Cirrhosis: Comparison with the Child Score aniel Urbain, Nathalie Petit, Fazia Mana, Filip Sermon, Peter van Hautem, Axe1 Bossuyt O M2043 A Simple Noninvasive Index Can Predict Significant Fibrosis in HIV-HCV Coinfected Patients Richard K. Sterling, Scott K. Fung, Jorge A. Marrero, Mary' M2044 S. Wilson, R. Todd Stravitz, Velimir A. Luketic, Arun J. Sanyal, Melissa J. Contos, A. S. Mills, Mitchell L. Shiffman, Anna S. F. Lok Osteoporosis in Chronic Liver isease M2045 Kazuyoshi Suzuki, Junko Takahashi, Satomi Sugiyama, Kazutomo Suzuki, Hajime Kuwayama Body Composition and Metabolic Alterations in Chronic Hepatitis C (HCV) Mono-lnfection and HIV/HCV Co- M2046 Infection Irina Kaplounov, llen ngelson, Safak Reka, onald Kotler O Clinical Course of Chronic Hepatitis C in Patients with Very High Serum Alpha-fetoprotein Levels and Normal Hepatic Imaging Stevan A. Gonzalez, Ira M Jacobson Factors Associated with HCV-stage Ill/IV Fibrosis: A Retrospective Study of a Large Cohort of US Patients Ke-Qin Hu, Namgyal L. Kyulo, Victor W. Xia, Shirley X. Hu, onald J. Hillebrand, Chang-Hong Yu Impact of Past HBV Infection on the Natural History of Chronic Hepatitis C and Treatment Outcome Maher Azzouz, iana Little, onna Bingham, Gagan K. Sood Lower Rates of Histologic Progression in HCV, HIV Co- Infected Patients Versus HCV Infected Inmates in the Louisiana epartment of Corrections Monica Pradhan, Lanier Hagood, William Cassidy Clinical Value of Total HCV Core Antigen etection and Quantification Mahmoud M. Omar, Ayman Abdel-Aziz, man Abdel-Aziz, Laila Mohamed, Ahmad Abu-Madian AM-5:00 PM Hall F Mo~ial Convention Center Sponsored by: AGA; Liver and Biliary PORTAL HYPRTNSION AN VASCULAR ISASS OF TH LIVR Results of a Prospective Systematic Screening for Hepatic Localisation in Patients with Rendu-Osler- Weber isease : Correlation with Age, Sex and Genotype Rodica Gincul, Guillaume Gautier, Gaetan Lesca, Benedicte tienne-mastroianni, Pascale Fouque, Luc Henry, Jean- Francois Cordier, Henry Plauchu, Jean-Christophe Saurin Up-regulation of nnos and Associated Increase in Vasorelaxation in Superior Mesenteric Arteries in Portal Hypertension Lars Jurzik, Reiner Wiest, Rainer H. Straub, Juer~en Schoelmerich Inflammatory Cytokines Induce MAdCAM-I and Mediate e~4137 ependent I.ymphocytc Adhesion on Murine Hepatic ndothelial Cells i, vitro Tomoaki Ando, Jdm P'lrod, NIc'~il>nJcr,~alui~,, P> I,ud,,~, Taka>hi Joh, Makoto Itola, 3. Ste\cn Aie:,:andcr Protective ffect of Zinc L-Carnosine in Gastric Muco~a of Portal Hypertensive Rats aisuke Watanabe, Michiro Otaka. Ken lchilo Md.zar.:i Takashi G<o, Kouichi \'hum qhigel,>,h[ Ohmhllq],{. l<,a_-itl, Yoneyama, ai~,uke %gay, a, Ft KaLc/ol<a, Totnol>t ~,ll:l~,x~t Ryutaro Yoshino, Masaru Od0.,dain::7,, Sumiu \Vatau,d~ Rofacoxib, a Highly Selective Cyclooxygenasc-2 Inhibitor, Ameriolates Portal Hypertension and Sinusoidal Capillarization in Cirrhotic Rats Jiyao Wang, Chuantao Tu, Jinsheng Guo Ascitic Fluid Lactoferrin: A Novel Marker for Rapid iagnosis of Spontaneous Bacterial Peritonitis (SBP) in Patients with Liver Cirrhosis Mansour A. Parsi, Lynn Manteuffel, Nizar N. Zein Recombinant Activated Factor VII (rfviia) in the Treatment of 13 Patients with Severe and Active Bleeding sophageal Varices Rafael Romero-Castro, Francisco Pellicer-Bautista, Manuel Jimenez-Saenz, Manuel Gomez-Parra, Angel Sendon-Perez, Maria. Guerrero-Aznar, Juan M. Herrerias-Gutierrez enotes W Poster of istinction P-197

4 POSTR SSSIONS--COMBIN SCINC M2047 High Resolution Contrast CT: A Potentially Useful Screening Strategy for sophageal Varices Roman Perri, Mihnea Chiorean, Linda Stadheim, Harshad evarbhavi, Jayant Talwalkar, Jeff Fidler, Joel Fletcher, Patrick Kamath AM-5:00 PM Hall F M2058 M2059 Matrix Metalloproteinases (MMPs) in Chromosomally Unstable (CIN) Colorectal Cancers (CRCs) May Mediate the Invasive Potential Kazuhiro Kashiwagi, Ajay God, C. Richard Boland Leptin and Leptin Receptor Patterns as pigenic Factors in Colon Cancer Iradj Sobhani, Mohammad Abolhassani, Thomas Aparicio, Karen Leroy, Marie-Therese Chaumette, Jean-Charles elchier, Antoinette Lemoine M O N A Y MAY 17 Sponsored by: Gastrointestinal Oncology CANCR PROGRSSION AN MTASTASIS M M M2050 M2051 M2052 M2053 M2054 M2055 M2056 M2057 vidence for a Role of Mast Cells in the evelopment of 1, 2-imethylhydrazine-lnduced Intestinal Adenomas in Mice Jochen Wedemeyer, Stephen J. Galli The Porphyrin-Polyamine Conjugate SL Prevents uodenal and Intestinal Tumors in the Min Mouse Model of Adenomatous Polyposis Russell F. Jacoby, Carolyn. Cole, Benjamin J. Frydman, Ronald A. Lubet, Laurence J. Marton Selective ownregnlation of Transcriptional Suppresor SNAIL ecreases Intestinal Tumorigenesis in APC ~ Mouse Ramesh K. Wall St., Jennifer Koetsier, Patrick L. Iversen, John Hart, Madhavi Madugula, hananjay Kunte, Hemant K. Roy Cell Cycle ependent Telomere Maintenance by Telomerase or ALT in Immortalized Human sophageal Squamous pithelial Cells Alexander von Werder, Michael Quante, Christine Fulda, Gitta Goessel, Birgit Jacobmeier, Hideki Harada, Yasir Suliman, Hubert. Blum, Oliver G. Opitz Malignant Transformation of Primary Human Oral Squamous pithelial Cells Using a efined Set of Genetic Alterations Gitta Goessel, Michael Quante, Alexander von Werder, Christine Fulda, Hiroshi Nakagawa, Yasir Suliman, William C. Hahn, Hubert. Blum, Anil K. Rustgi, Oliver G. Opitz Prostaglandin L own-regulates p27 ~Pl in Invasive Colon Cancer Cells. A Mechanism for Colon Cancer Progression? llama Pal, Teresa Tran, Andrzej Tamawski Microtopography of the xtracellular Matrix Critically Regulates Cell Motility and Morphology Sarah Glover, Cecile Perrault, Roger Tran-Son-Tay, Richard V. Benya xpression Profiling Suggests a Regulatory Role of Stromal Cells and Inflammation in Invasive Colonic Adenocarcinoma Alain Barrier, Franck Chiappini, Pierre-Yves Boelle, Chantal Tse, idier Brault, Thierry Andre, Sidney Houry, Francois Lacaine, Michel Huguier, Antoine Flahault Chemoprevention of Colonic Polyps by Balsalazide: An xploratory, oulbe-blind, Placebo-Controlled Study Jonathan Terdiman, James Gumm, Young S. Kim, Marvin H. Sleisenger, Vivian Weinberg, Sharon Colson, Vino Verghese, Ann Hayes, Lorin K. Johnson Novel Pathway to Focal Adhesion Kinase Activation by Hyperosmotic Stress: Role of c-src, p38map Kinase, RhoA, Racl and Cdc42 J. Adrian Lunn, nrique Rozengurt M2060 M2061 M2062 M2063 M2064 M2065 M2066 M2067 M2068 M2069 Potential Role of Monocyte-Chemoattractant Protein-1 in Macrophage Cyclooxygenase-2 xpression in Colonic Adenoma Shu Tanaka, Atsushi Tatsuguchi, Seiji Futagami, Ken Wada, Taku Tsukui, Katya Gudis, Teruyuki Kishida, Chouitsu Sakamoto eoxycholic Acid Upregulates an Invasive and Metastatic Potential in Human Colon Cancer Cell Line Kim Hyun-Soo, Chang Hwa In, Balk Soon Koo, Lee ong Ki, Kwon Sang Ok TRAIL Receptors xpression Affect Graft-Versus-Tumor (GVT) ffect Against Gastrointestinal Tumor Keisuke Tateishi, Miki Ohta, Bayasi Guleng, Hideaki Ijichi, Yasuo Tanaka, Jun Imamura, Takaaki Imamura, Tsuneo Ikenoue, Yasuyuki Fukushima, Takayuki Kawakami, Jazag Arnarsanaa, Fumihiko Kanai, Takao Kawabe, Masao Omata Increased xpression of Insulin Like Growth Factor 1 (IGF1) and/or Its Receptor (IGF1R) in Gastrinomas Is Associated with Low Curability, Increased Growth and evelopment of Metastases Masayuki Furukawa, Carmen Mateo, Akio Sakamoto, Terry Moody, Jose Serrano, Robert T. Jensen Microsatellite Instability in Colorectal Cancer. Prognostic Significance and Role in the Prediction of Benefit from Adjuvant Chemotherapy Rodrigo Jover, Asociacion spanola de Gastroenterologia Nuclear Survivin Is a Novel Prognostic Marker in Neuroendocrine Gastroenteropancreatic Tumor isease Patricia Grabowski, Sonja Griss, Christian Arnold, ieter Hoersch, Rudolf Arnold, Bernhard Heine, Harald Stein, Martin Zeitz, Hans Scherubl Prognostic Significance of Lymphatic Vessel Invasion in Primary Resected Adenocarcinomas of the sophagogastric Junction Burkhard. H. A. yon Rahden, Hubert J. Stein, Marcus Feith, Karen Becker, J. Ruediger Siewert xpression of Matrix-Metalloproteinases (MMP) and xtracellular Matrix Molecules uring Liver Metastasis of Colorectal Carcinoma: A Gene-Microarray Based Survey Wolfgang M. Brueckl, Isabel Zeittraeger, Roland S. Croner, Thomas Foertscb, Andreas Jung, Thomas Papadopoulos, Frank Boxberger, Thomas Kirchner, Werner Hohenberger, ckhart G. Hahn, Axel Wein Gastrointestinal Stromal Tumors: Towards a Clinically Reliable Prognostic Scale Pascal Bucher, Jean-Fracois gger, Peter Villiger, Leo Buhler, Philippe Morel Gastrointestinal Tract (GIT) Amyloidosis in Plasma cell yscrasias (PC): A escriptive Analysis at a Large Referral Center Curuchi P. Anand, Giampaolo Talamo, Guido Tricot, hiraj Yadav P-198 ~ enotes W Poster of istinction

5 POSTR SSSIONS--COMBIN SCINC M2070 l M2071 M2072 M2073 M2074 M2075 M2076 M2077 M2078 M2079 M2080 Prognostic Impacts of Thymidine Phosphorylase and ihydropyrimidine ehydrogenase in Colorectal Cancer with Respect to Stage: Immunohistochemistry with New Monoclonal Antibodies Yukihiko Tokunaga, Keiichi Takahashi, Toru Saito Growth Behaviour and Prognosis of Patients with Untreated Metastatic or Locally Advanced Gastroenteropancreatic (GP) Neuroendocrine Tumors Tina Badihian, Anja Sprenger, Hans-Helge Mueller, Klaus- Jochen Klose, Rudolf Arnold Prognostic Factors and Survival in 144 Patients with Gastro-ntero-Pancreatic Neuroendocrine Tumors Francesco Panzuto, Silvia Nasoni, Maria Sofia Cattaruzza, Massimo Milione, Sara Cassetta, Valentina Tornatore, Michela i Fonzo, Gabriele Capurso, Vito. Corleto, Cesare Bordi, Gianfranco elle Fave Has the Implementation of a Two Week Rule Impacted on Mortality in Upper GI Cancers? An Audit at Two istrict General Hospitals Faiyaz Mohammed, Achuth Shenoy, Nerukav Radakrishnan, Bashir Rameh, Ravi Sharma, Laura Quest, avid Foster, Khurshid Akhtar, Regi George etection of Micrometastasis in Bone Marrow in Patients with Gallbladder Cancer Juan C. Roa, Xabier de Arextabala, Angelica Melo, Gaspar Faria, Ivan Roa Neuroendocrine Tumors of the Gastroenteropancreatic Tract: Patient Characteristics, Survival and Clinical Outcome Uta Berndt, Ulrich-Frank Pape, Michael Bohmig, Nikolaus Tiling, Ursula Plockinger, Bertram Wiedenmann Prognostic Factors for Long-Time Survival in arly Carcinoma of the Upper Gastrointestinal-Tract Marcus Feith, Hubert J. Stein, J. Ruediger Siewert Prognostic Molecular Biomarkers in GISTs Adam Hassan, Alexander Zaika, Regine Schneider-Stock, Gina Petront, Markku Miettinen, Wa'el l-rifai xtramedullary Plasmacytomas (MP) Involving the Gastrointestinal Tract (GIT) in Plasma Cell yscrasias (PC): A escriptive Analysis at a Large Referral Center for PC Curuchi P. Anand, Giampaolo Talamo, Guido Tricot, Michele Fox, hiraj Yadav Immunohistochemical xpression of P63 Protein Is a Parameter of Malignant Potential in Colorectal Carcinomas Tatsuyoshi Yamamoto Ratio of Involved To Resected Lymph Nodes and Histologic Curability.Predict the Prognosis of Patients with Gastric Cancer After Curative Resection Antonio Soriano-Izquierdo, Antoni Castells, Manuel Pera, Maria Pellise, Francisco Rodriguez-Moranta, Gloria Fernandez-sparrach, Sergi Castellvi-Bell, Virginia Pinol, Oscar Vidai, Josep I. lizalde, Josep Maria Pique AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology TRANSLATIONAL RSARCH II Iressa, a Small Molecule GFR Antagonist, Unmasks M2081 GF Spare-Receptors in Mouse Colon Sharad Khare, Nathaniel Little, Sonia Cerda, Reba Mustafi, Nirmita Kumar, Juan Kong, Christopher Moore, Loren Joseph, Yan Chun Li, Alessandro Fichera, Marc Bissonnette Antitumor Activity of the Selective GF-Receptor- M2082 Tyrosine Kinase Inhibitor Gefitinib (Z1839) in Neuroendocrine Gastrointestinal Tumor Cells Michael Hoepfner, Andreas P. Sutter, Alexander Huether, Bastian Gerst, Martin Zeitz, Hans Scheruebl Pattern of ifferential Gene xpression in Colon Cancer M2083 in Response to Selective COXo2 Inhibition Sinead M. Byrne, Glen A. oherty, Geraldine M. Scully, Peter M. oran, Frank. Murray, esmond J. Fitzgerald The Thomsen-Friedenreich-Specific Peanut Lectin M2084 Stimulates Proliferation of Colon Cancer Cells via C44v6-Mediated Phosphorylation of c-met Ravinder Singh, Barry J. Campbell, Jonathan M. Rhodes Histamine HrReceptor Antagonists Suppress Growth of M2085 Colorectal Cancer Implants by Inhibiting Tumor Angiogenesis in Mice Kazuki Izumi, Kazuyoshi Tomita, Susumu Okabe Genetic and Protein Analysis of TGFb-Receptor II M2086 Signaling in Human GI Carcinoids Is Predictive of isease Aggression Mark Kidd, Robert Camp, Shrikant Mane, Irvin M. Modlin xtracellular Pressure Stimulates Colon Cancer Cell M2087 Proliferation via a PKC- and TK-ependent Mechanism Mary F. Walsh, Russell Woo, Richard J. Gilbert, Marc. Basson Up-Regulation of 25-Hydroxy-Vitamin -lol-hydroxylase M2088 by Butyrate in Caco-2: A New Molecular Link in Colonic pithelial Cell Growth Regulation and Colon Cancer Prevention Oliver Schroeder, Sinan Turak, Juergen Stein P38 MAPK Signaling Pathway Is Involved in Butvrate M2089 Induced VR-xpression Carolin aniel, Tanja Gaschott, Oliver Schroedcr, Jucrgcn Stein Pressure Stimulates Colon Cancer Cell Adhesion by a M2090 Pathway Involving Src, PI3 Kinase, AKT, and FAK Vijayalakshmi Thamilselvan, Neelesh Nundkumar, \lar~ Basson M2091 Modulation of Angiogenesis-Relatcd Protein Synthesis by Valproic Acid in Intestinal Tumor Cells imitrios Zgouras, Juergen Stein M2092 M2093 M2094 Loss of xpression of the GF-Receptor Related Protein (RRP) Is a Common vent in ifferent Models of Colon Cancer va M. Schmelz, di Levi, Adhip P. N. Majumdar M3 Muscarinic Receptor and Bile Acid Mediated Colon Cancer Proliferation by MAPK, PI3K Signal Activation Ying Qian, Harold Frucht pigallocatechin-3-gallate Blocks the ffect of Bile Acids on pidermal Growth Factor Receptor Signaling Pathways in Colon Caner Cells Ying Qian, Weihuang ong, Harold Fmcht enotes W Poster of istinction P-199

6 POSTR SSSIONSmCOMBIN SCINC " /i ~ /!% i i O Y MAY 17 AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity NUTRITION, ISAS AN CANCR M2095 M2096 M2097 M2098 M2099 M2100 M2101 M2102 M2103 M2104 M2105 M2106 Validation of a Food Frequency and iet Questionnaire in Subjects with Irritable Bowel Syndrome Sandy Park, Nancy Ling, Mark Pimentel Impact of Ascites on Gastric Accommodation and Nutritional Intake in Patients with Cirrhosis and Ascites Bashar Aqel, James Scolapio, Rolland C. ickson, Omer Bumett, rnest Bouras ifferences in iet and Colonic Bacterial Metabolism That Might Account for the Low Risk of Colon Cancer in Native Africans Stephen J.. O'Keefe, Y. Carrim, Tian van der Merwe, Scan McGarr, Philip Hylemon, Stephen Hertzler Thalidomide in the Treatment of Cancer Cachexia: A Randomised Placebo Controlled Trial John N. Gordon, Timothy M. Trebble, Timothy Johns, Richard. llis, Hamish. uncan, Patrick M. Goggin The Chemopreventive Polyphenol Resveratrol Induces Cl- Secretion in T84 Colon Cancer Cells Irina Blumenstein, Benjamin Keserue, Freya Woher, Juergen Stein Peripheral Blood Mononuclear Cell (PBMC) Mitochondrial Complex I (MC-I) Activity as a Marker of Nutritional Status in Patients with Cirrhosis Bashar Aqel, James Scolapio, Khursheed N. Jeejeebhoy, Francoise Briet Correlation of Tumors in the Large Intestine with Concentrations of Serum Lipids, Gastrin and Arteriosclerosis Kazuhiro Imatake, Teruaki Matui, Sachio Takekawa, Yoshikazu lwasaki, Hiroshi Kikuchi, Miyo Iida, Hidetoshi Yamazaki, Hideki Satou, Kenichi Takasuna, Tomoaki Watanabe, Ariyoshi Iwasaki, Yasuyuki Arakawa The Apoptosis-Inducing ffect of the N-3 Fatty Acid oeosahexaenoic on Colorectal Cancer Cells Is Mainly Mediated by the xtrinsic Pathway Xavier Llor, Anna Giros, lisenda Pons, Adolfo Rio, Miquel A. Gassull Role of Supplemental Calcium in the Recurrence of Colorectal Adenomas: A Meta-analysis of Randomized Controlled Trials Aasma Shaukat, Nicole Scouras, Holger Schunemann Impact of Social Status on Malnutrition in Hospitalized Patients Matthias Pirlich, Tatjana Schuetz, Heinrich J. Luebke, Herbert Lochs isproportionate ecrease of Muscle Strength in Patients with Low Body Cell Mass Kristina Norman, Tatjana Schuetz, Martin Kemps, Heinrich Luebke, Herbert Lochs, Matthias Pirlich Intestinal Mediators of nergy Homeostasis in Liver Cirrhosis Ajmal Omar, smatollah Kasim, Tatjana Schuetz, Silja Mueller, Thomas Kroenke, Georg Brabant, Herbert Lochs, Johann Ockenga AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity PRBIOTICS, PROBIOTICS AN FUNCTIONAL FOOS The Influence of Synbiotic Consumption on M2107 Proliferation in the Mucosa of Polypectomised Human Subjects Yvonne Clune, Maddalena Salvadori, Michael Benett, Michael O'Riordan, Colum unne, Gerald O'Sullivan, John K. Collins, Giovanna Caderni Two Candidate Biomarkers to Measure the Functionality M2108 and ffectivity of Pre- and Probiotics in Healthy Volunteers Vicky e Preter, Tom Vanhoutte, Kristof Verbrugghe, Luc e Vuyst, Geert Huys, Jean Swings, Kristin Verbeke Fructo-Oligosaccharides aten at Breakfast elay M2109 Gastric mptying of the Main Meal Luigi Benini, Laura Rigo, Naika Tacchella, lettra Marangoni, Fosca eiorio, Federico Ghirelli, Renzo Santi, Roberto Martini, Italo Vantini Comparative Study on the Fermentation of Pectin, M2110 Cellulose and Lactulose Using Hydrogen Breath Test, and Its Relationship with Fecal Flora aisuke Chinda, Shigeyuki Nakaji, Shinsaku Fukuda, Juichi Sakamoto, Tadashi Shimoyama, Takao Oyama, Tomohiko Fujisawa, Atsushi Terada, Akihiro Munakata Synbiotic Consumption Modulates the Genotoxic M2111 Potential of Faecal Water (FW) and Genotoxic amage in the Gut Mucosa Yvonne Clune, Annett Klinder, Michael Benett, Michael O'Riordan, Colum unne, Gerald O'Sullivan, John K. Collins, Beatrice Pool-Zobel ffects of Bovine Colostrum in iclofenac Induced Gut M2112 Injury and Bacterial Translocation in Rat Jeong Wook Kim, Woo Kyu Jeon, un Jeong Kim, Myong Suk Shin, o Hyun Lee, Joon Sup Yeom, Hyo Soon Park, Sac Kyung Chang, Jae Hyuk o, on Sub Park The ffect of a Probiotic rink With L Plantarum 299v M2113 on the Bacterial Composition in Faeces and Mucosal Biopsies of Rectum and Colon Ascendens. Goossens, aisy Jonkers,. Stobberingh, Reinhold Stockbrugger Colonic ffects of the Polyol Isomalt in Humans M2114 Andrea Gosmer, Michael Blaut, Victoria Schaeffer, Gunhild Kozianowski, Stephan Theis, Michael Klingeberg, Yvonne ombrowski, ierk Martin, Hardi Luehrs, Ralph Melcher, Juergen Schauber, Theodor Kudlich, onata orbath, Thomas Menzel, Wolfgang Scheppach ffects of Probiotics in Helicobacter pylori radication M2115 Therapy veliina Myllyluoma, Lea Veijola, Tuija Poussa, Heikki Vapaatalo, Hilpi Rautelin, Riitta Korpela ffect of Consumption of a Fermented Milk Containing M2116 the Probiotic Lactobacillus casei N on the Intestinal Microbiota of Healthy Humans Violaine Rochet, Lionel Rigottier-Gois, Malene Sutren, Marie N. Krementscki, Claude Andrieux, Jean P. Furet, Patrick Taillez, Florence Levenez, Agnes Mogenet, Jean L Bresson, Severine Meance, Antony Leplingard, Joel ote In vivo Colonic Synthesis of Butyric Acid (BA) and M2117 Colonic Mucosal Cell Proliferation (CP) in Pigs Fed Lactulose (LACTUL) and/or Inulin (IN) C. L. Kien, Wendy L Frankel P enotes W Poster of istinction

7 POSTR SSSIONS--COMBIN SCINC M2118 M2119 Bovine Colostrum Ameliorates the Bacterial Translocation and Intestinal ndotoxemia in 5-FU Treated Rats Jeong Wook Kim, Woo Kyu Jeon, un Jeong Kim, Seung Sei Lee, Joon Sup Yeom, Hyo Soon Park, Myong Suk Shin, In Kyung Sung, Chung 11 Sohn, Byeong Kim, Hong Jin Min, Yong Kyun Cho, ong I1 Park Comparative valuation of Three ifferent Breath Test Substrates for Assessment of Orocaecal Transit Time in Healthy Volunteers Vicky e Preter, Tamara Coopmans, Anja Luypaerts, Karen Geboes, Kristin Verbeke SSAT Poster Session AM-5:00 PM Hall F OTHR/MISCLLANOUS A New Optical Method of valuating Tactile Sensation M2120 for Robotic Surgery: Use of 1Hb in the Analysis of Tissue Blood Flow Soji Ozawa, Junya Oguma, Yasuhide Morikawa, Toshiharu Furukawa, Masaki Kitajima Results of Primary Surgical Treatment of M2121 Gastrointestinal Stromal Tumors Pascal Bucher, Peter Villiger, Jean-Francois gger, Leo Buhler, Philippe Morel a Vinci Robotic Surgical xperience at a University M2122 Setting: First One Hundred Cases Brian Zebrowski, Sonja Kinney, Cori McBride, mitry Oleynikov oes the Pneumoperitoneum with CO2 Alter the Ultra- M2123 structuture of the Mesothelium? Marcos T.A. Rosario, Ulysses Ribeiro Jr., Carlos. P. Corbett, Alberto Ozaki, Claudio Bresciani, Bruno Zilberstein, Joaquim J. Gama-Rodrigues Squamous Cell Carcinoma of Anal Canal - A Changing M2124 ntity in ra of HIV isease? Rabi Kundu, Franco Niccini, avid Henry, Scott Fisher, eborah Nagle, Susan Gordon Changing Trends in lliopsoas Abscess M2125 ennis K. Schimpf, Krishnan Raghavendran, Rebecca Read, Muhamad Kulaylat iagnosing Cancer with Untreated Fresh Lymph Node M2126 and Surgical Specimens of Gastrointestinal Tract Using Contact Microscope Method Hitoshi Satodate, Haruhiro Inoue, Shin-l Kudo Robotic Assisted Laparoscopic Surgery M2127 Sergio Rojas-Ortega, Luis Sanchez enotes W Poster of istinction P-201

8 POSTR SSSIONS--BASIC SCINC S i~t ii Y < MAY 18 AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a p~orit.y as you visit the poster session. AM-5:00 PM Hall F BILIARY PHYSIOLOGY, TRANSPORT CHOLANGIOCYT BIOLOGY, XPRIMNTAL CHOLSTASIS Molecular Identification of a Novel Gene ncoding T905 Human Organic Cation/Adriamycin Transporter OCAI: A New Transporter which Mediates the Cellular Influx of Adriamycin in Cancer Cells Mitsunori Okabe, Michiaki Unno, Koh Miura, Takayuki Mizoi, Seiichi Ishii, Kenichi Shiiba, lwao Sasaki Comprehensive Study of the ffects of Rifampicin and T906 Ursodeoxycholic Acid on Genes and Proteins Involved in Regulation, Transport and etoxification of Biliary Compounds in Gallstone Patients Harms-Ulrich Marschall, Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, agmar Silbert, Ulf iczfalusy, Lisbet Benthin, Rosita Grundstrom, Staffan Sahlin, Curt inarsson, Michael Trauner Human MRP1 Mediates ATP-dependent Transport of T907 Unconjugated Bilirubin (UCB) Igino Rigato, Lorella Pascolo, Cristina Femetti, onald J. Ostrow, Claudio Tiribelli Bilirubin (BI) Protects Plasma Membrane from Osmotic T908 Stress but Increases Bile Salt (BS) etergency: Implications in Cholestasis Piero Portincasa, Antonio Moschetta, Michele Petruzzelli, Michele Vacca, M. Krawczyk, Giuseppe Palasciano Cystic Fibrosis Mice Have an Impaired Capacity to T909 ilute Their Bile, Leading to Increased Cytotoxicity Frank A. J. A. Bodewes, Marcel J. C. Bijvelds, Rick Havinga, Juul Bailer, Hugo R. de Jonge, Henkjan J. Verkade Non-Obese iabetic Mice Have Shortened Biliary T910 Crystal Observation Time Shannon J. Graewin, Keun-Ho Lee, James M. Kiely, Carol L. Svatek, Attila Nakeeb, Henry A. Pitt Alpha Adrenergic Antagonist Indoramin Increases T911 Gallbladder Motility in Subjects with Gall Stone isease Subhasish Sengupta, Prasenjit Modak, Noreen MacCawley, Ronan Waldron, Luke J.. O'onnell Clarithromycin Increases Gall Bladder mptying in Both T912 Normal Subjects and in Subjects with Gall Stone isease Subhasish Sengupta, Prasenjit Modak, Noreen MacCawley, Ronan Waldron, Luke J.. O'onnell StAR5, a Liver Related START omain Protein, Binds T913 Both Cholesterol and Oxysterols, and Markedly Increases Cellular Cholesterol Content Following Overexpression in Primary Rat Hepatocytes aniel Rodriguez-Agudo, Shunlin Ren, Phillip Hylemon, alila Marques, Seema Gupta, Antonio del Castillo-Olivares, Gregorio Gil, William M. Pandak BASIC SCINC The Anionic Polypeptide Fraction Is Present on the T914 Gallbladder Apical pithelium and Favours Biliary Cholesterol Absorption Stefano Ginanni Corradini, Francesca Liguori, Nicole omingo, Giovanni Tebala, Cristina Ripani, Rosanna e Marco, Maria Siciliano, Maria Assunta Meini, Paulette Lechene dela Porte, enis Lairon, Huguette Lafont, Adolfo Attili istinct Quantitative Trait Loci (QTL) etermine High- T915 ensity Lipoprotein (HL) Cholesterol Levels and Cholesterol Gallstone Formation in Crosses of the Inbred Mouse Strains PRA/i, with l/lnj and BA/2J Henning Wittenburg, Malcolm A. Lyons, Renhua Li, Gary A. Churchill, Joachim Mossner, Martin C. Carey, Beverly Paigen ifferences in Bile Acid and Cholesterol Metabolism in T916 Mice xpressing the Human Rather Than the Mouse CYP7AI Gene Allen Cooper, Sung-Joon Lee, Jean Chen Prolactin Regulates, by an Autocrine Mechanism, T917 Cholangiocyte Proliferation Through Ca2+/PKC - ependent Activation of Src/Raf-1/RK1/2 SilviaTaffetani, Heather Francis, Shannon Glaser, Julie Venter, Ramona Reichenbach, Luca Marucci, Jo Lynne Phinizy, Giammarco Fava, Antonio Benedetti, Gianfranco Alpini Translational Regulation of XIAP Mediates Survival of T918 Malignant Human Cholangiocytes uring Hypoxia Carla Marienfeld, Yoko Yamagiwa, Valorie Chiasson, Linda Brooks, Fanyin Meng, Tushar PateI ATP-ependent Regulation of Biliary Secretion Through T919 P2X4 Purinergic Receptors Tom Matzakos, Sylene Goodwin, Gregory Fitz, Brian octor Cholangiocyte Infection by Rhesus Rotavirus Results in T920 Chemokine xpression Which May be the Initiating vent in Biliary Atresia Steven R. Allen Sr., Bryan onnelly, Jorge Bezerra, Richard Ward, Greg Tiao ffect of Calcium on Volume Activated Chloride T921 Current in Mouse Cholangiocyte Biyi Chen, Grant. Nicol, Won Kyoo Cho ndogenous Opioids Inhibit Cholangiocyte Proliferation T922 in the BL but not in the Normal Rat Marco Marzioni, Gianfranco Alpini, Stefania Saccomanno, Luciano Trozzi, Shannon Glaser, Giampiero Macarri, Antonio Benedetti Susceptible Role and istinct istribution of ph T923 Members in Cholangiocyte Koji Fukushima, Yoshiyuki Ueno, Noriatsu Kanno, Yuki Moritoki, Jun lnoue, Tooru Shimosegawa lntracellular Calcium Has a Permissive Role in T924 Regulatory Volume ecrease in Mouse Cholangiocytes Won Kyoo Cho, Vicki Siegrist Histamine Stimulates Cholangiocyte Proliferation T925 Through Transduction Pathways Involving the HI and H2 Histamine Receptor Subtypes Heather Francis, Silvia Taffetani, Shannon Glaser, Julie Venter, Jo Lynne Phinizy, Ramona Reichenbach, Giammarco Fava, omenico Alvaro, Luca Marucci, Antonio Benedetti, Marco Marzioni, Gianfranco Alpini P-202 ~ enotes W Poster of istinction

9 POSTR SSSIONS~BASIC SCINC T926 Neuropeptide Y (NPY) Inhibits Cholangiocarcinoma Growth by Interaction with a G-protein Coupled Receptor by Ca 2+ ependent Modulation of Src/RK1/2 Phosphorylation Giammarco Fava, Shannon Glaser, Heather Francis, jo Lynne Phinizy, Julie Venter, Ramona Reichenbach, Silvia Taffetani, Marco Marzioni, Luca Marucci, Antonio Benedetti, Gianfranco Alpini A Nuclear Receptor Ligand own-regulates Cytosolic T927 Phospholipase A2 (cpla2) xpression to Reduce bile Acid-induced Cyclooxygenase 2 (COX-2) Activity in Cholangiocytes: Implication of Anti-carcinogenic Action of Farnesoid X Receptor (FXR) Agonist aisuke Komichi, Susumu Tazuma, Tomoji Nishioka, Hideyuki Hyogo, Kazuhiko Tsuboi, Minoru Sakomoto, Keishi Kanno, Yoshihiro Numata, Atsushi Yamaguchi, Toshiya Kobuke, Michihiro Nonaka, Motoki Inoue, Keiko Iwamoto, Yoshitaka Nabeshima, Mami Watanabe, Kazuaki Chayama Microarray Analysis of Biliary Tract Obstruction T928 Hongtao Wang, Robert O. Heuckeroth MdrU- Mice with Sclerosing Cholangitis: A Model of T929 Chronic Cholestasis to Study the Role of the Adaptive Response of Hepatobiliary Transport Systems and Bile Acid Synthetic nzymes Gernot Zollner, Martin Wagner, Peter Fickert, Andrea Fuchsbichler, Judith Gumhold, agmar Silbert, Kurt Zatloukal, Grace L. Guo, Hanns-Ulrich Marschall, Helmut enk, Michael Trauner Melatonin Ameliorates Cholestatic Liver Injury in Rats T930 with Acute Obstructive Jaundice Afsar Barlas, Sebnem Tekin, ilek Bangir, Scrap Arbak, Goksel Sener, Cumhur Yegen, Berrak C. Yegen ffect of Peroxisome-Proliferator Agonist Receptor-alpha T931 (PPAR-alpha) and -gamma (PPAR-gamma) on Hepatocellular Organic Cation Uptake by S1c22all (Oct1) Seth R. Sweetser, Richard M Green AASL Poster Session AM-5:00 PM Hall F CLL AN MOLCULAR BIOLOGY, STM CLLS Keratin 8 And 18 Over-xpression Is Not a Prerequisite T932 for Mallory Body Formation and Pancreatic Injury Ikuo Nakamichi, iana M. Toivola, Sara A. Michie, Helene Baribault, Robert G. Oshima, M. Bishr Omary Site-Specific Inhibition of Keratin Phosphorylation in T933 Transgenic Mice Alters the Regulation of Multiple Hepatocyte Cellular Proteins Nam-On Ku, Jian Liao, Gurmil Gendeh, Jay Lorch, M. Bishr Omary T934 T935 T936 SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitisinduced Carcinogenesis Takafumi Yoshida, Akihiko Yoshimura, Michio Sara The Role of Protein Phosphatase 1 in Human Hepatocellular Carcinoma Patrick Klein, Chad Wiesenauer, Jennifer Choi, C. M. Schmidt ffect of iabetes () on Rat Liver Fluid-Phase ndocytosis (FP) and Signal Transduction: Comparison to ffects of Cholera Toxin (CTX) Rebecca W. Van yke, Marianne R. Lewis Plasmid NA-based Gene Therapy of T937 Hyperbilirubinemia in Gunn Rats Istvan anko, Zhen Jia Thyl-Positive Mesenchymal Cell> Pronmte tile T938 Maturation of C49F-Positi~e tiepalic Progenihw ( ells in the Mouse Fetal Liver Toshitaka /Ioppo. I lidca]<i Fu]ii, To>tin, l lil-o,c. K,'~l.~r,, Yasuchika, Hisaya Azuma, Shinji lgal~& Maqato Naih, Takafumi Machimoto, ]wao Ikai Propranolol Increases Markers of Liver Injury and T939 Promotes Accumulation of Hepatic Oval Cells Jude A. Oben, Tania Roskam~, >tqicli Nang, Zhipi~g Ih HuiZhi Lin, Nicoletta Sinelli, Anna Mac iehl LL is an ssential Additive for Serum Free Culture of T940 Fetal Hepatic Stem Cells Amit Shukla, Ian S. Currie, Neff M. Masson, Rosey A. L. Bayne, Olivier J. Garden, Rowan W. Parks, James A. Ross Treatment of Surgically Induced Acute Liver Failure by T941 Transplantation of HNF4-Overexpression mbryonic Stem Cells Xiao-Ling Kuai, Shu-ong Xiao Transplantation of Human Umbilical Cord Blood Cells T942 to Injured Liver Sei Kakinuma, Yujiro Tanaka, Kinji Asahina, Kentaro Okamura, Yoshinori Soeno, Chise Tateno, Katsutoshi Yoshizato, Kenichi Teramoto, Shigeki Arii, Naoya Sakamoto, Hirobumi Teraoka, Mamoru Watanabe AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders BACTRIAL FACTORS IN HLICOBACTR PATHOGNSIS Helicobacter pylori Urease Binds to C74 and Stimulates T943 Gastric pithelial Cell Responses Associated with Pathogenesis llen J. Beswick, avid Bland, Soumita as, Giovanni Suarez, Johanna Sierra, Victor. Reyes Helicobacter Pylori Outer Membrane Protein (HP1125) T944 Induces endritic Cell Maturation and Function Sivaprakash Rathtnavelu, John Kao, Yana Zavros, Juanita L. Merchant Fur- and Iron-responsive Gene Regulation of the T945 Helicobacter Pylori Superoxide ismutase Gene sodb Florian. rnst, Georg Homuth, rnst J. Kuipers, Jeroen Stool, Stefan Bereswill, Manfred Kist, Johannes G. Kusters, Arnoud H. M van Vliet The Presence of the Cag Pathogenicity Island Is T946 Associated with Increased ROS Scavenging by Helicobacter Pylori Raymond G. J. Pot, Jacco J. Briede, rnst J. Kuipers, Arnoud H. M. van Vliet, Jos C. S. Kleinjans, Johannes G. Kusters The H. pylori Periplasmic ol-carbonic Anhydrase Is T947 Required for Acid Survival avid R. Scott, lizabeth A. Marcus, Yi Wen, George Sachs Adhesin Function of the Outer Membrane Protein HorB T948 in the Human Gastric Pathogen Helicobacter Pylori William Shelling, Kieran Ryan, Paul W. O'Toole The NikR Protein Governs Transcriptional Regulation of T949 NixA-Mediated Nickel-Uptake in Helicobacter pylori Arnoud H. M van Vliet, Florian. rnst, rnst J. Kuipers, Angela Heijens, Jeroen Stool, Johannes G. Kusters enotes W Poster of istinction P-203

10 T U S A Y MAY 18 Purified Outer Membrane Proteins of Helicobacter pylori T950 Produce Interleukin-8 from Gastric pithelial Cells Hong Lu, Jeng Y. Wu, Takahiko Kudo, ong-hyeon Kwon, avid Y. Graham, Yoshio Yamaoka valuation of the Association Of Nine Helicobacter T951 Pylori Virulence Factors with Strains Involved in Low Grade Gastric MALT Lymphoma Philippe Lehours, Armelle Menard, Sandrine upouy, Bernard Bergey, Frederique Richy, Frank Zerbib, Agnes Ruskone-Fourmestraux, Jacques Tankovic, Jean-Charles elchier, Francis Megraud istinct iversity of the cag Pathogenicity Island of T952 Helicobacter Pylori in Japan Takeshi Azuma, Masahiro Ohtani, Akiyo Yamakawa, Shiho Yamazaki, Yukinao Yamazaki, Yoshihide Keida ffect of Lansoprazole on the Motility of H.Pylori - T953 xamination Using a Novel ark-field Image igital Analysis System Hidekazu Suzuki, Shuhei Nishimoto, Kumiko Kurabayashi, Yuka Abiko, Tatsuhiro Masaoka, Hiromasa Ishii Co-infection: Helicobacter pylori (Hp) / Human T954 Immunodeficiency Virus (HIV) Martin Olmos, Valentina Araya, Ana Fanin, Hugo Concetti, duardo Piskorz, duardo Coronado Quesad, Femando Magnanini Adhesion Molecules in Children with Helicobacter Pylori T955 (Hp) Gastritis in ifferent Stages of isease to 2 Strains of lip Vasundhara Tolia, P. Michael Long, Kim Boyer, angfei Wang, Ron Thomas, Raymond Podzorski Response of Murine and Human Gastric pithelial Cells T956 to Cag A-Positive and -Negative Strains of Helicobacter pylori Malini Basu, Thomas G. Blanchard, Steven J. Czinn Isogenic Variation of Helicobacter Pylori Strain Resulting T957 in Heteroresistant Antibacterial Phenotypes in a Single Host in vivo Sun-Young Lee, Yong Chan Lee, Jae J. Kim, Jae Hee Pyo, ong H. Kwon, Jong Chul Rhee Correlation Between Helicobacter pylori OipA Protein T958 xpression with oipa Gene Switch Status Takahiko Kudo, Zhannat Z. Nurgalieva, Margaret. Conner, Sue Crawford, Stefan Odenbreit, Rainer Haas, avid Y. Graham, Yoshio Yamaoka Scanning lectron Microscopic valuation of Interaction T959 Between Helicobactor pylori and AGS Cells Jin Hal Hyun, Rok Son Choung, Yong Sik Kim, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Urn, Sang Woo Lee, Jai Hyun Choi, Chang uck Kim, Ho Sang Ryu, Hye-Jung Min, un-kyung Park, Chang-Sub Uhm Helicobacter Pylori and Platelet Aggregation. Results of T960 Screening of 26 Bacterial Strains Paul A. Corcoran, ermot Cox, John C. Atherton, Stephen W. Kerrigan, Richard M. Peek, esmond J. Fitzgerald, Frank. Murray, Michael F. Byrne POSTR SSSIONS--BASIC SCINC AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders IMMUN RSPONS TO HLICOBACTR INFCTION Suppression of Lymphocyte Apoptosis at Low Levels of T961 H. pylori Infection Francoise Bussiere, Rupesh Chaturvedi, Justin Gainor, Adina Scholz, aniel Fertel, Michael Yao, ana Sloane, Yulan Cheng, Hangxiu Xu, Keith T. Wilson L-arginine Uptake Regulates H. pylori-induced T962 Macrophage inos Rupesh Chaturvedi, Francoise Bussiere, Preston Kim, Yulan Cheng, Hangxiu Xu, Robert A. Casero Jr., Keith T. Wilson Interleukin-2 Gene Polymorphisms Associated with T963 Increased Risk of Gastric Atrophy by Helicobcter Pylori Shozo Togawa, Takashi Job, Tadayuki Oshima, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, Nobuyuki Hamajima, Nobuyuki Katsuda, Hidemi Ito, Kazuo Tajima, Keitaro Matsuo, Makoto hoh Helicobacter Pylori Activates Nf-KB via both Classical T964 and Alternative Pathway in Murine and Human Peripheral Blood Mononuclear Cells Tomoya Ohmae, Yoshihiro Hirata, Shin Maeda, Wataru Shibat~, Ayako Yanai, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, Masao Omata The Fas Pathway Modulates Immunity uring T965 Helicobacter pylori Vaccination sther Galindo-Mata, Yaron Avitzur, Nicola Jones Humoral and Cellular Immune Response to H. pylori T966 Infection According to Age Gifone A. Rocha, Taciana F. Soares, Andreia M.C. Rocha, Anfrisina S.T. Carvalho, Paulo Bittencout, Celso A. Oliveira, Ana M. M. F. Nogueira, Rodrigo Correa-Oliveira, Ana M.C. Faria, Olindo A. Martins-Filho, Monica M..A. Cabral, ulciene M.M. Queiroz Recruitment and Activation of endritic Cells by T967 Helicobacter pylori Kathleen M. Anderson, Thomas G. Blanchard, Steven J. Czinn T968 IL-113 and IL-7 Levels in the Gastric Tissues Were Correlated to ~/8 T Cells Counts : levation of v8 2/v8 1 T Cell Ratio in Chronic Gastritis with Strong lga reponses to H. Pylori Urease Seiji Futagami, Tetsuro Hiratsuka, Kenji Suzuki, Masanori Kusunoki, Nobue Ueki, Yoko Shinji, Kei Shinoki, Hitoshi Nishigaki, Ken Wada, Kazumasa Miyake, Taku Tsukui, Kazushi Ohashi, Masumi Shimizu, Hidemi Takahashi, Katya Gudis, Choitsu Sakamoto AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology COLON CANCR: BASIC I Role of Inducible Nitric Oxide Synthase (NOS2) in T969 evelopment of Apoptosis Resistance in Colon Carcinogenesis Hana Holubec, Claire M. Payne, Harris Bemstein, Carol Bemstein, Katerina vorakova, Ronnie Fass, Harinder Garewal P-204 ~ enotes W Poster of istinction

11 POSTR SSSIONS~BASIC SCINC T970 Rebamipide Inhibits Gastric Cancer Cell Growth via Induction of Cyclin-ependent Kinase lnhibitors p21 and p27: Possible Involvement of Smad Signaling Pathway Tetsuya Tanigawa, Rama Pal, Tetsuo Arakawa, Andrzej S. Tarnawski Cyclooxygenase-2 (COX-2) Gene xpression and T971 Prostaglandin Production Is ecreased in Human Adenocarcinoma Cells After Treatment with Physiological oses of icosapentaenoic Acid Grace Lee, lizabeth K. Lund, Yong Ping Bao, Michael Rhodes, Ian Johnson The Role of PPAR"/in Colon Carcinogenesis, and Its T972 Relation to 13-Catenin Nobutaka Fujisawa, Masato Yoneda, Hirokazu Takahashi, Takako Yoshii, Atsushi Nakajima, Nobuyuki Matsuhashi Butyrate Sensitization of Gastric and Colon Cancer T973 Cells to the Growth inhibitory ffect of GF-Receptor Related Protein (RRP) Udayini Kodali, Richard Jaszewski, Adhip P. N. Majumdar Cox-2 Inhibition by Celecoxib Is Not Sufficient to T974 Induce Apoptosis or Inhibit Cell proliferation in Human Colon Carcinoma Cell Line Shahar Lev-Ari, iana Kaznov, Ludmila Strier, Hadas vory-sobol, Liora Madar-Shapiro, ov Lichtenberg, Nadir Arber AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology GASTRIC CANCR: BASIC Identification of Gastric Cancer Patients by Serum T975 Protein Profiling Matthias bert, Jorn Meuer, Jan Wiemer, Stephanie Lamer, Thomas Buschmann, Volker Seibert, Ulrich Traugott, Hans- Ulrich Schulz, Marc Reymond, Peter Malfertheiner, Christoph Roecken Clustering of Overexpressed Genes in Chromosomal T976 omains in GJ Carcinomas Natalie Koon, Alexander Zaika, Christopher Moskaluk, Steven Powell, Henry F. Frierson, Wa'el l-rifai A p53 Genetic Polymorphism of Gastric Cancer: T977 ifference Between arly Gastric Cancer (GC) and Advanced Gastric Cancer (AGC) Sun Young Yi, Han Hyo Lee, Jun Sik Nam, Moon Sun Yeom, un Jung Lee, Sung-Ae Jung, Ki-Nam Shim, Hye- Kyung Jung, oe-young Kim, Yoo Kwon, I1-Hwan Moon iagnosis of Malignancy and Benign Alterations in T978 Gastric Biopsy Specimen by mrna xpression Profiling and Multivariate Statistical Methods Orsolya Galamb, Ferenc Sipos, Bela Molnar, Zsolt Tulassay Gastric Cancer and Multidrug Resistance: oes COX2 T979 and PgP Play a Role? Alba Rocco, Rosario Caruso, Luciana Rigoli, Laura Ottini, Renato Mariani-Costantini, Gerardo Nardone ysregulation of Calcium Signaling Molecules in Gastric T980 Cancer Narendra Sankpal, Alexander Zaika, Henry F. Frierson, Steven Powell, Wa'el l-rifai Hypermethylation Status Around xon 1 of XIAP- T981 Associated Factor 1 in Human Gastric and Colon Cancer Cell Lines Bing Zou, Marrie C. M. Lin, S. K l.am, ShuiPing I u. YI Yang, Jide Wang, Hua He, Jun Zhong Pcng, H. F. Ktmg. Benjamin C. Y. Wong Mutation Analysis of hsmad2 Gene in Gastric Adcnoma T982 Byung Kyu Park, Kyung Hwa Park, Sun A. Kim, Sung Pll Hong, Hye Won Chung, Seung Woo Park, Jae-Bock Chu*/g. Han-Soo Kim, Si Young Song ecreased Adhesion of Human Gastric Cancer Cells to T983 Vascular ndothelial Cells by Introduction of Human N- Acetylgalactosaminyhransferase Which Forms Carbohydrate Antigen xclusively xpressed in Normal Gastric Fundic Mucosa Yuki I. Kawamura, Ryuko Fukunaga, Rei Kawashima, Taeko ohi Helicobacter Pylori xpress an 2a Homologue? T984 Barbara Ada Manzo, Ian R. Sanderson, James W. Wilson T985 p27 ~api Regulates the Apoptotic Response of Gastric pithelial Cells to Helicobacter Pylori Hidetoshi guchi, Sung Soo Kiln, Stephanie Carpemier, Steven F. Moss Cyclooxygenase-2 Modulated Cyclin ~, Cyclin- T986 dependent Kinases (Cdks) and Promoted Cell Cycle Progression in Gastric Tumor Growth Stimulated by Nicotine Vivian Y. Shin, Yi-Ni Ye, Marcel W. L. Koo, Chi-Hin Cho IL-6 May Prevent Submucosal Invasion in a Mouse T987 Gastric Cancer Model by Augmenting Leucocyte Infiltration Meegan Howlett, Louise M. Judd, Brendan Jenkins, Matthias rnst, Andrew S. Giraud Inhibition of Gastric Cancer-associated Angiogenesis by T988 Cox-2 Inhibitor or Anti-sense cna Yuan-Gen Fu, Joseph J. Y. Sung, Kai-Chun Wu, Han-Pin Wu, ai-ming Fan, Wai K. Leung Gastric Neoplasia in CH-1 Knockout Mice Using N- T989 methyl-n-nitrosourea Carcinogenesis: A Murine Model of Hereditary iffuse Gastric Cancer Vanessa Blair, Amanda Charlton, Iain G. Martin, Parry Guilford Resveratrol Bypasses Mitochondrial Signals to Initiate T990 Apoptosis in Gastric Adenocarcinoma Cells William L. Riles, Bashar M. Attar, Oksana Holian T991 Potent Inhibition of Cell Growth and Angiogenesis in Gastric Cancer by Small Interference RNA for Cydooxygenase (COX)-2 Kai-Chun Wu, Li-Ping Yao, Tao-Zhi eng, Han-Ping Wu, Yang-Lin Pang, ai-ming Fan Gastric Cancer: ifferential xpression of Genes Inside T992 the RBB2 Amplicon Alexander Zaika, Asta Varis, Sakari Knuutila, Christopher Moskaluk, Wa'el 1-Rifai enotes W Poster of istinction P-205

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