POSTER SESSIONS--COMBINED SCIENCE COMBINED SCIENCE

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1 POSTR SSSIONS--COMBIN SCINC COMBIN SCINC AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F Modal Convention Center AUTOIMMUN LIVR ISAS AN HPATIC IMMUNOLOGY M1977 M1978 M1979 M1980 M1981 M1982 M1983 M1984 M1985 M1986 Progressive Fibrosis in Autoimmune Hepatitis espite Corticosteroid Therapy: Frequency and Predisposing Factors Albert J. Czaja, Herschel A. Carpenter Nonstandard Autoantibodies as Prognostic Markers in Autoimmuue Hepatitis Albert J. Czaja, Zakera Shums, Gary L. Norman Clinical and Histologic Features in Patients with Acute Autoimmune Hepatitis William R. Kessler, Naga Chalasani, Oscar W. Cummings, Lawrence Lumeng, George ckert, Paul Y. Kwo arly Treatment Response Predicts the Need for Liver Tranplantation in Autoimmune Hepatitis P. Tan, Cam Ghent, Paul Marotta, P. Adams Factors Predicting Relapse/Poor Outcome in Type 1 Autoimmune Hepatitis: Role of Cirrhosis evelopment, Patterns of Transaminases uring Remission and Plasma Cell Activity Sumita Verma, Basuki Gunawan, Michel Mendler, Sugantha Govindrajan, Allan Redeker Transplant Immunosuppressive Agents in Non- Transplant Chronic Autoimmune Hepatitis: The CASL xperience with Mycophenolate Mofetil and Tacrolimus Nazira Chatur, Alnoor Ramji, Vince Bain, Mang Ma, Paul Marotta, Cam Ghent, Leslie Lilly, Jenny Heathcote, Marc eschenes, Urs Steinbrecher, ric Yosbida Biochemical, Immunological and HLA Gene ifferences Between Autoimmune Liver iseases and Hepatic Overlap Syndromes Sergio Zepeda-Gomez, Juan Carlos Zapata-Colindres, Octavio Gomez-scudero, Angelica Rodriguez-Carreon, Francisco Pax, Julio Granados, Marco Antonio Olivera- Martinez Frequency and Significance of Antibodies to Saccharomyces cerevisiae in Autoimmune Hepatitis: Clues to Concurrent Mucosal isease? Albert J. Czaja, Zakera Shums, Peter T. onaldson, Gary L. Norman CXCR6 Mediates Recruitment of C8 Lymphocytes to Inflamed Liver Tohru Sato, Henrik Thorlacius, Brent Johnston, Wenkai Xiang, an R. Littman, ugene C. Butcher High Affinity Antigen eletion of Hepatic T Cells Is ependent on Kupffer Cells Yuhshi Kuniyasu, Suhail Marfani, Irteza Inayat, Shehzad Sheikh, Wajahat Mehal AASL Poster Session AM-5:00 PM Hall F Modal Convention Center CLINICAL AN XPRIMNTAL HPATOBILIARY CANCR M1987 M1988 M1989 M1990 M1991 M1992 M1993 M1994 M1995 M1996 Functional xpression of TWAK in Human Hepatocellular Carcinoma Tomoyuki Kawakita, Katsuya Shiraki, Yutaka Yamanaka, Yumi Yamaguchi, Yukiko Saitou, Naoyuki nokimura, Norihiko Yamamoto, Hiroshi Okano, Kazushi Sugimoto, Kazumoto Murata, Takeshi Nakano PPAR-Alpha L162V Polymorphism in Human Hepatocellular Carcinoma lif S. Koytak, Hasibe Verdi, Filiz Akbiyik, Ayca A. rgul, Ramazan Idilman, Kubilay Cinar, Mithat Bozdayi, Cihan Yurdaydin, Ozden Uzunalimoglu, Hakan Bozkaya Pyrimidine Nucleoside Phosphorylase (PyNPase) Activity in the Liver Tissue of Patient with Hepatocellular Carcinoma lkuo Nagashima, Tadahiro Takada, Hisae Inuma, Kota Okinaga High Nociceptin Content in Human Hepatocellular Carcinoma Tissue Andrea Horvath, Aniko Folhoffer, Timea Csak, Peter L. Lakatos, Monika B. Hantos, Kornelia Tekes, Attila Szijarto, Peter Kupcsulik, Andras Kiss, Judit Halasz, Zsuzsa Schaff, Ferenc Szalay Influence of Large Intrahepatic Blood Vessels on Gross and Histological Characteristic of Lesions Generated by Radiofrequency Ablation in a Pig Liver Model Katsuyoshi Tamaki, Ichiro Shimizu, Hiroshi Shibata, Man Urata, Atsuo Ooshio, Hiroshi Fukuno, Akemi Tsutsui, Susumu Ito Suppressive ffect of Menatetrenone, a Vitamin K2 Analog, on Recurrence of Hepatocellular Carcinoma Improved Patient Survival Toshihiko Mizuta, Iwata Ozaki, Kyosuke Yamaluoto, Kazuma Fu]imoto Recurrence of Hepatocellular Carcinoma After Curati'~c Ablation Therapy Haruhiko Yoshida, Ryosuke Tateishi, Shuichiro Shima. Tomonori Fujishima, Masatoshi Akamat>u, Shuntato Obj. Shinpei Sato, Takuma Teratani, Takao Kawabe, Macao Omata Radiofrequency Ablation Combined with Transcadlcler Arterial Chemoembolization for Small Hepatocelhdar Carcinomas Hiroshi Aikata, Shintaro Yakaki, Shutetsu Tci, Hivoto Ishihara, Shoichi Takahashi, Ka:uaki Chayama Artificial Ascites Using a Special Needle to Avoid GI Tract Perforation in Radiofrequency Ablation (RFA) for Liver Tumors Shuicbiro Shiina, Takuma Teratani, Shinpei Sato, Ryosuke Tateishi, Tomonori Fujishima, Takashi Ishikawa, Yuji Kondo, Noriyo Yamashiki, Norio Mine, Miho Kanda, Shuntaro Obi, Masatoshi Akamatsu, Hideo Yoshida, Yukihiro Koike, Masatoshi Imamura, Keisuke Hamamura, Haruhiko Yoshida, Takao Kawabe, Masao Omata Prognostic Factors Associated with Treatment Response to Octreotide in Advanced Hepatocellular Cancer (HCC) Gerhard G. Treiber, Thomas Wex, Christoph Roecken, Peter Malfertheiner enotes W Poster of istinction P-195

2 POSTR SSSIONS--COMBIN SCINC M1997 Hepatic Arterial Infusion Chemotherapy Prolonged Survival of Patients with Advanced Hepatocellular M2010 Carcinomas Ryota Masuzaki, Seiji Kawazoe, Hirohisa Shigematsu, Kyosuke Yamamoto, Kazuma Fnjimoto Idiopathic Fibrosing Biliary Strictures in Surgical Resected Patients with Presumed Cholangiocarcinoma: Clinical Comparison with Cholangiocarcinoma Harshad evabhavi, avid Nagorney, Michael Farnell, John onohue, Linda Stadheim, Gregory J. Gores M1998 M1999 Radiofrequency Ablation Following Selective Arterial mbolization for Hepatocellular Cancer; a Trial to M2011 Reduce the Tumor Volume Prior to Ablation Keisuke Hamamura, Naofumi Shirane, Hiroaki Fukuzawa, Kazunori Matsumura, Yoshihisa Tsukioka, Hideyuki Kin, Koichi Kojima M2012 Local Therapeutic Results of Computed Tomographyguided Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: Single Application for 270 Tumors in 80 Patients M2013 Keiji Hayashi, Hiroyasu Ina, Mikio Tezuka, Yoichi Okada, Tetsuya lrie Most Primary Lymphomas of the Liver Are iffuse Large B Cell Lymphomas Michael Torbenson, dward Weir, Susan Abraham Premalignant isease Characterization in a Mouse Model of Infectious Liver Cancer Arlin B. Rogers, Mark T. Whary, Nataliya Sundina, Samuel R. Boutin, James G. Fox Liver Cell Proliferation Induced by Tri-Iodothyronine Is Associated with an Up-Regulation of the Bcl-3 Proto- Oncogene Raza Malik, avid Brown, Humphrey Hodgson r M O N A Y MAY 17 M2000 M2001 M2002 M2003 M2004 M2005 M2006 M2007 M2008 M2009 Historical Pilot Trail for valuation of Percutaneous Radiofrequency Ablation Therapy in Patients with M2014 Hepatocellular Carcinomas Compared to Percutaneous thanol Injection Therapy Seiji Kawazoe, Ryota Masuzaki, Hirohisa Shigematsu, Kyosuke Yamamoto, Kazuma Fujimoto Chemoembolization Therapy of Hepatocellular Cancer - Results of Selective mbolization Therapy in 112 Patients Alan A. Weiss, Stephen Ho, Peter Munk, Stephen Chung, Charles Scudamore, Chuck Paltiel Results of a Pilot Study with Octreotide for Patients with Hepatocellular Carcinoma Linda M. Stadheim, Ziad M. Hassoun, Ugochukwu C. Nzeako, K. V. Narayanan Menon, Jayant A. Talwalkar, Nicholas F. LaRusso, Gregory J. Gores Management of Brain Metastasis of Hepatocellular Carcinoma Jamy Yong, Mei Yee Leung, Chi Ming Lam, Sheung Tat Fan M2015 M2016 Percutaneous Ultrasound-guided Radiofrequency Ablation with the Artificial Pleural ffusion for Hepatocellular Carcinoma in the Hepatic ome Yasunori Minami, Masatoshi Kudo, Toshihiko Kawasaki, M2017 Hobyung Chung, Chikara Ogawa, Tatsuo Inoue, Yasuhiro Sakaguchi, Hiroki Sakamoto, Hitoshi Shiozaki Radiofrequency Ablation (RFA) for lderly Patients with Hepatocellular Carcinoma (HCC) Takuma Teratani, Shuichiro Shiina, Shinpei Sato, Shuntaro Obi, Masatoshi Akamatsu, Tomonori Fujishima, Ryosuke Tateishi, Miho Kanda, Noriyo Yamashiki, Norio Mine, Yuji M2018 Kondo, Haruhiko Yoshida, Takashi Ishikawa, Haruhiko Yoshida, Takao Kawabe, Masao Omata The Assessement by Using Multiditecter-row CT in the Treatment of Hepatocellular Carcinoma with Radiofrequency Thermal Ablation ' Shintaro Takaki, Hiroshi Aikata, Shutetsu Tel, Hiroto M2019 Ishihara, Shoichi Takahashi, Kazuaki Chayama The ffect of ML on Liver Transplantation for Hepatocellular Carcinoma Julie M Winn, Karl T. srason Stage ependent Therapeutic Strategies and Results for 180 Patients with Hilar Cholangiocarcinoma Marcus Wiedmann, Uli Ringel, Hubert Witzigmann, Frieder Berr, Johann Hauss, Joachim Moessner, Karel Caca Activation of Proinflammatory Cytokines by Photodynamic Therapy in Cholangiocellular Carcinoma Juergen Bauditz, Maria-Anna Ortner, Andreas Giese, Herbert Lochs M2020 Chronological Gene xpression Profiling in the Premalignant Phase of a Mouse Model of Infectious Liver Cancer Samuel R. Boutin, Arlin B. Rogers, Zeli Shen, Jennifer A. Love, Rebecca C. Fry, James G. Fox Inflammatory Cell Populations uring Hepatic Carcinogenesis Lisa M. Yerian, Robert A. Anders, Mark W. Lingen, John Hart AASL Poster Session AM-5:00 PM Hall F Mot-ial Convention Center HPATITIS C: IAGNOSIS AN NATURAL HISTORY Novel Hepatitis C Virus Genotyping Method Based on Mass Spectrometric Analysis of Oligonucleotide Fragments Yun Joon Kim, Hyun J. Chung, Mi Sun Ji, Kang M. Kim, Jung-Hwan Yoon, Byeong G. Kim, Hyo-Suk Lee, Chung Y. Kim, Soo-Ok Kim, Wangdon Yoo, Sun P. Hong HCV Core Quasispecies Change Is Associated with nd Stage Liver isease in a Longitudinal Cohort of HCV and HCV/I-I1V Infected Patients with Inherited Bleeding isorders Hongxing Qin, Norah J. Shire, Susan. Rouster, M.. yster, James J. Goedert, Margaret J. Koziel, Kenneth. Sherman Fibrosis Progression Is ependent upon Hepatic Inflammation in Patients with Chronic HCV Joon Mo Myung, Iliana Bouneva, Jennifer Salvatori, Melissa J. Contos, Mitchell L. Shiffman, Richard K. Sterling, R. Todd Stravitz, Velimir A. Luketic, Andrea Ferreira- Gonzalez, A. S. Mills, Arun J. Sanyal The Interleukiu-10 Receptor 1 (IL-10R1) G330R Allele Is Associated with Advanced Fibrosis in Chronic HCV-1 Infection Harald Hofer, Julius B. Neufeld, Christoph Oesterreicher, Paul Grundmer, Fritz Wrba, Peter Ferenci, Christoph Gasche High Prevalence of Novel Genotypes in Vietnamese Patients with Chronic Hepatitis C Mindie H. Nguyen, Huy Trinh, Ruel T. Garcia, Jing Ning, mmet Keeffe Natural History of Acute Hepatitis C in a U.S. Cohort M2021 Andrew Ross, Raymond T. Chung P enotes W Poster of istinction

3 POSTR SSSIONS~COMBIN SCINC M2022 M2023 M2024 M2025 M2026 M2027 M2028 M2029 M2030 M2031 M2032 M2033 M2034 Proposal and Validation of the AST/ALT Ratio for Predicting the Presence of Significant Fibrosis in M2035 Patients with Chronic Hepatitis C doardo Giannini, Luca Mastracci, Paola Ceppa, Roberto Testa A Comparative Study on Natural History of Chronic M2036 Hepatitis C in Patients with Chronic Renal Failure (CRF) vs. Normal Renal Function (NRF) Ke-Qin Hu, Steve Lee, Namgyal k. Kyulo, Victor W. Xia, onald J. Hillebrand, Shirley X. Hu, Chang-Hong Yu M2037 HCV RNA etection in Catrimox-14 Whole Blood and Plasma Keynr Patel, Jeff Albrecht, Anouk ev, rin Owens, Shanon Heaton, Andrew Muir, Stephen Pianko, Paul J. Pockros, Andrew Conrad, Lawrence Blatt, John G. McHutchison M2038 Stellate Cell Activation and Fibrosis Progression in Recurrent Hepatitis C After Liver Transplantation Sripriya Balasubramanian, Christopher k Bowlus, Rajendra Ramsamooj, Byung K. Minh, Boris Ruebner, Lorenzo M2039 Rossaro Aminopyrine and Methacetin 13C-Breath Tests to Assess Hepatic Function in HCV-Related Chronic Liver isease nrico C. Nista, Immacolata A. Cazzato, Alessandro Armuzzi, Lucia Fini, Marcello Candelli, Maria A. Zocco, Lorenzo Zileri al Verme, Rosalba Finizio, Giovanni Gasbarrini, Antonio Gasbarrini oes Non-Alcoholic Fatty Liver isease (NAFL) and Its Risk Factors Affect the Progression of Fibrosis in HCV Patients? Joel Kertznus, Arie Regev, nrique Molina, Jonatan Konfino, Patricia Mendez, Adriana Arcila, ugene Schiff M2040 IN valuation of the isease Progression of Chronic 8 Hepatitis C by the Score efined by Platelet Count and Alubumin Level Kohsaku Sakaguchi, Akiko Fujiwara, Shin-Ichi Fujioka, Yasushi Shiratori A Validated Noninvasive Prsd, icl~llj~f Liver Fibrosis in M2041 Chronic Hepatit~C~ ~12~1~ ]~'~ Leon/~t~a,~O~.~, l~n~co Rossi, Bastiaan 8 I3~r~o[ ~el~rrge, Geoff Farrell, Geoffrey McCaughan, Ga~lN/~."Jeffrey The Clinical Utility of HCV RNA etection in Catrimox- M Whole Blood uring Therapy Keyur Patel, Jeff Albrecht, rin Owens, Anouk ev, Shanon Heaton, Andrew J. Muir, Stephen Pianko, Paul J. Pockros, Andrew Conrad, Lawrence Blatt, John G. McHutchison 13C-Aminopyrine Breath Test in Alcoholic and Virus C Related Cirrhosis: Comparison with the Child Score aniel Urbain, Nathalie Petit, Fazia Mana, Filip Sermon, Peter van Hautem, Axe1 Bossuyt O M2043 A Simple Noninvasive Index Can Predict Significant Fibrosis in HIV-HCV Coinfected Patients Richard K. Sterling, Scott K. Fung, Jorge A. Marrero, Mary' M2044 S. Wilson, R. Todd Stravitz, Velimir A. Luketic, Arun J. Sanyal, Melissa J. Contos, A. S. Mills, Mitchell L. Shiffman, Anna S. F. Lok Osteoporosis in Chronic Liver isease M2045 Kazuyoshi Suzuki, Junko Takahashi, Satomi Sugiyama, Kazutomo Suzuki, Hajime Kuwayama Body Composition and Metabolic Alterations in Chronic Hepatitis C (HCV) Mono-lnfection and HIV/HCV Co- M2046 Infection Irina Kaplounov, llen ngelson, Safak Reka, onald Kotler O Clinical Course of Chronic Hepatitis C in Patients with Very High Serum Alpha-fetoprotein Levels and Normal Hepatic Imaging Stevan A. Gonzalez, Ira M Jacobson Factors Associated with HCV-stage Ill/IV Fibrosis: A Retrospective Study of a Large Cohort of US Patients Ke-Qin Hu, Namgyal L. Kyulo, Victor W. Xia, Shirley X. Hu, onald J. Hillebrand, Chang-Hong Yu Impact of Past HBV Infection on the Natural History of Chronic Hepatitis C and Treatment Outcome Maher Azzouz, iana Little, onna Bingham, Gagan K. Sood Lower Rates of Histologic Progression in HCV, HIV Co- Infected Patients Versus HCV Infected Inmates in the Louisiana epartment of Corrections Monica Pradhan, Lanier Hagood, William Cassidy Clinical Value of Total HCV Core Antigen etection and Quantification Mahmoud M. Omar, Ayman Abdel-Aziz, man Abdel-Aziz, Laila Mohamed, Ahmad Abu-Madian AM-5:00 PM Hall F Mo~ial Convention Center Sponsored by: AGA; Liver and Biliary PORTAL HYPRTNSION AN VASCULAR ISASS OF TH LIVR Results of a Prospective Systematic Screening for Hepatic Localisation in Patients with Rendu-Osler- Weber isease : Correlation with Age, Sex and Genotype Rodica Gincul, Guillaume Gautier, Gaetan Lesca, Benedicte tienne-mastroianni, Pascale Fouque, Luc Henry, Jean- Francois Cordier, Henry Plauchu, Jean-Christophe Saurin Up-regulation of nnos and Associated Increase in Vasorelaxation in Superior Mesenteric Arteries in Portal Hypertension Lars Jurzik, Reiner Wiest, Rainer H. Straub, Juer~en Schoelmerich Inflammatory Cytokines Induce MAdCAM-I and Mediate e~4137 ependent I.ymphocytc Adhesion on Murine Hepatic ndothelial Cells i, vitro Tomoaki Ando, Jdm P'lrod, NIc'~il>nJcr,~alui~,, P> I,ud,,~, Taka>hi Joh, Makoto Itola, 3. Ste\cn Aie:,:andcr Protective ffect of Zinc L-Carnosine in Gastric Muco~a of Portal Hypertensive Rats aisuke Watanabe, Michiro Otaka. Ken lchilo Md.zar.:i Takashi G<o, Kouichi \'hum qhigel,>,h[ Ohmhllq],{. l<,a_-itl, Yoneyama, ai~,uke %gay, a, Ft KaLc/ol<a, Totnol>t ~,ll:l~,x~t Ryutaro Yoshino, Masaru Od0.,dain::7,, Sumiu \Vatau,d~ Rofacoxib, a Highly Selective Cyclooxygenasc-2 Inhibitor, Ameriolates Portal Hypertension and Sinusoidal Capillarization in Cirrhotic Rats Jiyao Wang, Chuantao Tu, Jinsheng Guo Ascitic Fluid Lactoferrin: A Novel Marker for Rapid iagnosis of Spontaneous Bacterial Peritonitis (SBP) in Patients with Liver Cirrhosis Mansour A. Parsi, Lynn Manteuffel, Nizar N. Zein Recombinant Activated Factor VII (rfviia) in the Treatment of 13 Patients with Severe and Active Bleeding sophageal Varices Rafael Romero-Castro, Francisco Pellicer-Bautista, Manuel Jimenez-Saenz, Manuel Gomez-Parra, Angel Sendon-Perez, Maria. Guerrero-Aznar, Juan M. Herrerias-Gutierrez enotes W Poster of istinction P-197

4 POSTR SSSIONS--COMBIN SCINC M2047 High Resolution Contrast CT: A Potentially Useful Screening Strategy for sophageal Varices Roman Perri, Mihnea Chiorean, Linda Stadheim, Harshad evarbhavi, Jayant Talwalkar, Jeff Fidler, Joel Fletcher, Patrick Kamath AM-5:00 PM Hall F M2058 M2059 Matrix Metalloproteinases (MMPs) in Chromosomally Unstable (CIN) Colorectal Cancers (CRCs) May Mediate the Invasive Potential Kazuhiro Kashiwagi, Ajay God, C. Richard Boland Leptin and Leptin Receptor Patterns as pigenic Factors in Colon Cancer Iradj Sobhani, Mohammad Abolhassani, Thomas Aparicio, Karen Leroy, Marie-Therese Chaumette, Jean-Charles elchier, Antoinette Lemoine M O N A Y MAY 17 Sponsored by: Gastrointestinal Oncology CANCR PROGRSSION AN MTASTASIS M M M2050 M2051 M2052 M2053 M2054 M2055 M2056 M2057 vidence for a Role of Mast Cells in the evelopment of 1, 2-imethylhydrazine-lnduced Intestinal Adenomas in Mice Jochen Wedemeyer, Stephen J. Galli The Porphyrin-Polyamine Conjugate SL Prevents uodenal and Intestinal Tumors in the Min Mouse Model of Adenomatous Polyposis Russell F. Jacoby, Carolyn. Cole, Benjamin J. Frydman, Ronald A. Lubet, Laurence J. Marton Selective ownregnlation of Transcriptional Suppresor SNAIL ecreases Intestinal Tumorigenesis in APC ~ Mouse Ramesh K. Wall St., Jennifer Koetsier, Patrick L. Iversen, John Hart, Madhavi Madugula, hananjay Kunte, Hemant K. Roy Cell Cycle ependent Telomere Maintenance by Telomerase or ALT in Immortalized Human sophageal Squamous pithelial Cells Alexander von Werder, Michael Quante, Christine Fulda, Gitta Goessel, Birgit Jacobmeier, Hideki Harada, Yasir Suliman, Hubert. Blum, Oliver G. Opitz Malignant Transformation of Primary Human Oral Squamous pithelial Cells Using a efined Set of Genetic Alterations Gitta Goessel, Michael Quante, Alexander von Werder, Christine Fulda, Hiroshi Nakagawa, Yasir Suliman, William C. Hahn, Hubert. Blum, Anil K. Rustgi, Oliver G. Opitz Prostaglandin L own-regulates p27 ~Pl in Invasive Colon Cancer Cells. A Mechanism for Colon Cancer Progression? llama Pal, Teresa Tran, Andrzej Tamawski Microtopography of the xtracellular Matrix Critically Regulates Cell Motility and Morphology Sarah Glover, Cecile Perrault, Roger Tran-Son-Tay, Richard V. Benya xpression Profiling Suggests a Regulatory Role of Stromal Cells and Inflammation in Invasive Colonic Adenocarcinoma Alain Barrier, Franck Chiappini, Pierre-Yves Boelle, Chantal Tse, idier Brault, Thierry Andre, Sidney Houry, Francois Lacaine, Michel Huguier, Antoine Flahault Chemoprevention of Colonic Polyps by Balsalazide: An xploratory, oulbe-blind, Placebo-Controlled Study Jonathan Terdiman, James Gumm, Young S. Kim, Marvin H. Sleisenger, Vivian Weinberg, Sharon Colson, Vino Verghese, Ann Hayes, Lorin K. Johnson Novel Pathway to Focal Adhesion Kinase Activation by Hyperosmotic Stress: Role of c-src, p38map Kinase, RhoA, Racl and Cdc42 J. Adrian Lunn, nrique Rozengurt M2060 M2061 M2062 M2063 M2064 M2065 M2066 M2067 M2068 M2069 Potential Role of Monocyte-Chemoattractant Protein-1 in Macrophage Cyclooxygenase-2 xpression in Colonic Adenoma Shu Tanaka, Atsushi Tatsuguchi, Seiji Futagami, Ken Wada, Taku Tsukui, Katya Gudis, Teruyuki Kishida, Chouitsu Sakamoto eoxycholic Acid Upregulates an Invasive and Metastatic Potential in Human Colon Cancer Cell Line Kim Hyun-Soo, Chang Hwa In, Balk Soon Koo, Lee ong Ki, Kwon Sang Ok TRAIL Receptors xpression Affect Graft-Versus-Tumor (GVT) ffect Against Gastrointestinal Tumor Keisuke Tateishi, Miki Ohta, Bayasi Guleng, Hideaki Ijichi, Yasuo Tanaka, Jun Imamura, Takaaki Imamura, Tsuneo Ikenoue, Yasuyuki Fukushima, Takayuki Kawakami, Jazag Arnarsanaa, Fumihiko Kanai, Takao Kawabe, Masao Omata Increased xpression of Insulin Like Growth Factor 1 (IGF1) and/or Its Receptor (IGF1R) in Gastrinomas Is Associated with Low Curability, Increased Growth and evelopment of Metastases Masayuki Furukawa, Carmen Mateo, Akio Sakamoto, Terry Moody, Jose Serrano, Robert T. Jensen Microsatellite Instability in Colorectal Cancer. Prognostic Significance and Role in the Prediction of Benefit from Adjuvant Chemotherapy Rodrigo Jover, Asociacion spanola de Gastroenterologia Nuclear Survivin Is a Novel Prognostic Marker in Neuroendocrine Gastroenteropancreatic Tumor isease Patricia Grabowski, Sonja Griss, Christian Arnold, ieter Hoersch, Rudolf Arnold, Bernhard Heine, Harald Stein, Martin Zeitz, Hans Scherubl Prognostic Significance of Lymphatic Vessel Invasion in Primary Resected Adenocarcinomas of the sophagogastric Junction Burkhard. H. A. yon Rahden, Hubert J. Stein, Marcus Feith, Karen Becker, J. Ruediger Siewert xpression of Matrix-Metalloproteinases (MMP) and xtracellular Matrix Molecules uring Liver Metastasis of Colorectal Carcinoma: A Gene-Microarray Based Survey Wolfgang M. Brueckl, Isabel Zeittraeger, Roland S. Croner, Thomas Foertscb, Andreas Jung, Thomas Papadopoulos, Frank Boxberger, Thomas Kirchner, Werner Hohenberger, ckhart G. Hahn, Axel Wein Gastrointestinal Stromal Tumors: Towards a Clinically Reliable Prognostic Scale Pascal Bucher, Jean-Fracois gger, Peter Villiger, Leo Buhler, Philippe Morel Gastrointestinal Tract (GIT) Amyloidosis in Plasma cell yscrasias (PC): A escriptive Analysis at a Large Referral Center Curuchi P. Anand, Giampaolo Talamo, Guido Tricot, hiraj Yadav P-198 ~ enotes W Poster of istinction

5 POSTR SSSIONS--COMBIN SCINC M2070 l M2071 M2072 M2073 M2074 M2075 M2076 M2077 M2078 M2079 M2080 Prognostic Impacts of Thymidine Phosphorylase and ihydropyrimidine ehydrogenase in Colorectal Cancer with Respect to Stage: Immunohistochemistry with New Monoclonal Antibodies Yukihiko Tokunaga, Keiichi Takahashi, Toru Saito Growth Behaviour and Prognosis of Patients with Untreated Metastatic or Locally Advanced Gastroenteropancreatic (GP) Neuroendocrine Tumors Tina Badihian, Anja Sprenger, Hans-Helge Mueller, Klaus- Jochen Klose, Rudolf Arnold Prognostic Factors and Survival in 144 Patients with Gastro-ntero-Pancreatic Neuroendocrine Tumors Francesco Panzuto, Silvia Nasoni, Maria Sofia Cattaruzza, Massimo Milione, Sara Cassetta, Valentina Tornatore, Michela i Fonzo, Gabriele Capurso, Vito. Corleto, Cesare Bordi, Gianfranco elle Fave Has the Implementation of a Two Week Rule Impacted on Mortality in Upper GI Cancers? An Audit at Two istrict General Hospitals Faiyaz Mohammed, Achuth Shenoy, Nerukav Radakrishnan, Bashir Rameh, Ravi Sharma, Laura Quest, avid Foster, Khurshid Akhtar, Regi George etection of Micrometastasis in Bone Marrow in Patients with Gallbladder Cancer Juan C. Roa, Xabier de Arextabala, Angelica Melo, Gaspar Faria, Ivan Roa Neuroendocrine Tumors of the Gastroenteropancreatic Tract: Patient Characteristics, Survival and Clinical Outcome Uta Berndt, Ulrich-Frank Pape, Michael Bohmig, Nikolaus Tiling, Ursula Plockinger, Bertram Wiedenmann Prognostic Factors for Long-Time Survival in arly Carcinoma of the Upper Gastrointestinal-Tract Marcus Feith, Hubert J. Stein, J. Ruediger Siewert Prognostic Molecular Biomarkers in GISTs Adam Hassan, Alexander Zaika, Regine Schneider-Stock, Gina Petront, Markku Miettinen, Wa'el l-rifai xtramedullary Plasmacytomas (MP) Involving the Gastrointestinal Tract (GIT) in Plasma Cell yscrasias (PC): A escriptive Analysis at a Large Referral Center for PC Curuchi P. Anand, Giampaolo Talamo, Guido Tricot, Michele Fox, hiraj Yadav Immunohistochemical xpression of P63 Protein Is a Parameter of Malignant Potential in Colorectal Carcinomas Tatsuyoshi Yamamoto Ratio of Involved To Resected Lymph Nodes and Histologic Curability.Predict the Prognosis of Patients with Gastric Cancer After Curative Resection Antonio Soriano-Izquierdo, Antoni Castells, Manuel Pera, Maria Pellise, Francisco Rodriguez-Moranta, Gloria Fernandez-sparrach, Sergi Castellvi-Bell, Virginia Pinol, Oscar Vidai, Josep I. lizalde, Josep Maria Pique AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology TRANSLATIONAL RSARCH II Iressa, a Small Molecule GFR Antagonist, Unmasks M2081 GF Spare-Receptors in Mouse Colon Sharad Khare, Nathaniel Little, Sonia Cerda, Reba Mustafi, Nirmita Kumar, Juan Kong, Christopher Moore, Loren Joseph, Yan Chun Li, Alessandro Fichera, Marc Bissonnette Antitumor Activity of the Selective GF-Receptor- M2082 Tyrosine Kinase Inhibitor Gefitinib (Z1839) in Neuroendocrine Gastrointestinal Tumor Cells Michael Hoepfner, Andreas P. Sutter, Alexander Huether, Bastian Gerst, Martin Zeitz, Hans Scheruebl Pattern of ifferential Gene xpression in Colon Cancer M2083 in Response to Selective COXo2 Inhibition Sinead M. Byrne, Glen A. oherty, Geraldine M. Scully, Peter M. oran, Frank. Murray, esmond J. Fitzgerald The Thomsen-Friedenreich-Specific Peanut Lectin M2084 Stimulates Proliferation of Colon Cancer Cells via C44v6-Mediated Phosphorylation of c-met Ravinder Singh, Barry J. Campbell, Jonathan M. Rhodes Histamine HrReceptor Antagonists Suppress Growth of M2085 Colorectal Cancer Implants by Inhibiting Tumor Angiogenesis in Mice Kazuki Izumi, Kazuyoshi Tomita, Susumu Okabe Genetic and Protein Analysis of TGFb-Receptor II M2086 Signaling in Human GI Carcinoids Is Predictive of isease Aggression Mark Kidd, Robert Camp, Shrikant Mane, Irvin M. Modlin xtracellular Pressure Stimulates Colon Cancer Cell M2087 Proliferation via a PKC- and TK-ependent Mechanism Mary F. Walsh, Russell Woo, Richard J. Gilbert, Marc. Basson Up-Regulation of 25-Hydroxy-Vitamin -lol-hydroxylase M2088 by Butyrate in Caco-2: A New Molecular Link in Colonic pithelial Cell Growth Regulation and Colon Cancer Prevention Oliver Schroeder, Sinan Turak, Juergen Stein P38 MAPK Signaling Pathway Is Involved in Butvrate M2089 Induced VR-xpression Carolin aniel, Tanja Gaschott, Oliver Schroedcr, Jucrgcn Stein Pressure Stimulates Colon Cancer Cell Adhesion by a M2090 Pathway Involving Src, PI3 Kinase, AKT, and FAK Vijayalakshmi Thamilselvan, Neelesh Nundkumar, \lar~ Basson M2091 Modulation of Angiogenesis-Relatcd Protein Synthesis by Valproic Acid in Intestinal Tumor Cells imitrios Zgouras, Juergen Stein M2092 M2093 M2094 Loss of xpression of the GF-Receptor Related Protein (RRP) Is a Common vent in ifferent Models of Colon Cancer va M. Schmelz, di Levi, Adhip P. N. Majumdar M3 Muscarinic Receptor and Bile Acid Mediated Colon Cancer Proliferation by MAPK, PI3K Signal Activation Ying Qian, Harold Frucht pigallocatechin-3-gallate Blocks the ffect of Bile Acids on pidermal Growth Factor Receptor Signaling Pathways in Colon Caner Cells Ying Qian, Weihuang ong, Harold Fmcht enotes W Poster of istinction P-199

6 POSTR SSSIONSmCOMBIN SCINC " /i ~ /!% i i O Y MAY 17 AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity NUTRITION, ISAS AN CANCR M2095 M2096 M2097 M2098 M2099 M2100 M2101 M2102 M2103 M2104 M2105 M2106 Validation of a Food Frequency and iet Questionnaire in Subjects with Irritable Bowel Syndrome Sandy Park, Nancy Ling, Mark Pimentel Impact of Ascites on Gastric Accommodation and Nutritional Intake in Patients with Cirrhosis and Ascites Bashar Aqel, James Scolapio, Rolland C. ickson, Omer Bumett, rnest Bouras ifferences in iet and Colonic Bacterial Metabolism That Might Account for the Low Risk of Colon Cancer in Native Africans Stephen J.. O'Keefe, Y. Carrim, Tian van der Merwe, Scan McGarr, Philip Hylemon, Stephen Hertzler Thalidomide in the Treatment of Cancer Cachexia: A Randomised Placebo Controlled Trial John N. Gordon, Timothy M. Trebble, Timothy Johns, Richard. llis, Hamish. uncan, Patrick M. Goggin The Chemopreventive Polyphenol Resveratrol Induces Cl- Secretion in T84 Colon Cancer Cells Irina Blumenstein, Benjamin Keserue, Freya Woher, Juergen Stein Peripheral Blood Mononuclear Cell (PBMC) Mitochondrial Complex I (MC-I) Activity as a Marker of Nutritional Status in Patients with Cirrhosis Bashar Aqel, James Scolapio, Khursheed N. Jeejeebhoy, Francoise Briet Correlation of Tumors in the Large Intestine with Concentrations of Serum Lipids, Gastrin and Arteriosclerosis Kazuhiro Imatake, Teruaki Matui, Sachio Takekawa, Yoshikazu lwasaki, Hiroshi Kikuchi, Miyo Iida, Hidetoshi Yamazaki, Hideki Satou, Kenichi Takasuna, Tomoaki Watanabe, Ariyoshi Iwasaki, Yasuyuki Arakawa The Apoptosis-Inducing ffect of the N-3 Fatty Acid oeosahexaenoic on Colorectal Cancer Cells Is Mainly Mediated by the xtrinsic Pathway Xavier Llor, Anna Giros, lisenda Pons, Adolfo Rio, Miquel A. Gassull Role of Supplemental Calcium in the Recurrence of Colorectal Adenomas: A Meta-analysis of Randomized Controlled Trials Aasma Shaukat, Nicole Scouras, Holger Schunemann Impact of Social Status on Malnutrition in Hospitalized Patients Matthias Pirlich, Tatjana Schuetz, Heinrich J. Luebke, Herbert Lochs isproportionate ecrease of Muscle Strength in Patients with Low Body Cell Mass Kristina Norman, Tatjana Schuetz, Martin Kemps, Heinrich Luebke, Herbert Lochs, Matthias Pirlich Intestinal Mediators of nergy Homeostasis in Liver Cirrhosis Ajmal Omar, smatollah Kasim, Tatjana Schuetz, Silja Mueller, Thomas Kroenke, Georg Brabant, Herbert Lochs, Johann Ockenga AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity PRBIOTICS, PROBIOTICS AN FUNCTIONAL FOOS The Influence of Synbiotic Consumption on M2107 Proliferation in the Mucosa of Polypectomised Human Subjects Yvonne Clune, Maddalena Salvadori, Michael Benett, Michael O'Riordan, Colum unne, Gerald O'Sullivan, John K. Collins, Giovanna Caderni Two Candidate Biomarkers to Measure the Functionality M2108 and ffectivity of Pre- and Probiotics in Healthy Volunteers Vicky e Preter, Tom Vanhoutte, Kristof Verbrugghe, Luc e Vuyst, Geert Huys, Jean Swings, Kristin Verbeke Fructo-Oligosaccharides aten at Breakfast elay M2109 Gastric mptying of the Main Meal Luigi Benini, Laura Rigo, Naika Tacchella, lettra Marangoni, Fosca eiorio, Federico Ghirelli, Renzo Santi, Roberto Martini, Italo Vantini Comparative Study on the Fermentation of Pectin, M2110 Cellulose and Lactulose Using Hydrogen Breath Test, and Its Relationship with Fecal Flora aisuke Chinda, Shigeyuki Nakaji, Shinsaku Fukuda, Juichi Sakamoto, Tadashi Shimoyama, Takao Oyama, Tomohiko Fujisawa, Atsushi Terada, Akihiro Munakata Synbiotic Consumption Modulates the Genotoxic M2111 Potential of Faecal Water (FW) and Genotoxic amage in the Gut Mucosa Yvonne Clune, Annett Klinder, Michael Benett, Michael O'Riordan, Colum unne, Gerald O'Sullivan, John K. Collins, Beatrice Pool-Zobel ffects of Bovine Colostrum in iclofenac Induced Gut M2112 Injury and Bacterial Translocation in Rat Jeong Wook Kim, Woo Kyu Jeon, un Jeong Kim, Myong Suk Shin, o Hyun Lee, Joon Sup Yeom, Hyo Soon Park, Sac Kyung Chang, Jae Hyuk o, on Sub Park The ffect of a Probiotic rink With L Plantarum 299v M2113 on the Bacterial Composition in Faeces and Mucosal Biopsies of Rectum and Colon Ascendens. Goossens, aisy Jonkers,. Stobberingh, Reinhold Stockbrugger Colonic ffects of the Polyol Isomalt in Humans M2114 Andrea Gosmer, Michael Blaut, Victoria Schaeffer, Gunhild Kozianowski, Stephan Theis, Michael Klingeberg, Yvonne ombrowski, ierk Martin, Hardi Luehrs, Ralph Melcher, Juergen Schauber, Theodor Kudlich, onata orbath, Thomas Menzel, Wolfgang Scheppach ffects of Probiotics in Helicobacter pylori radication M2115 Therapy veliina Myllyluoma, Lea Veijola, Tuija Poussa, Heikki Vapaatalo, Hilpi Rautelin, Riitta Korpela ffect of Consumption of a Fermented Milk Containing M2116 the Probiotic Lactobacillus casei N on the Intestinal Microbiota of Healthy Humans Violaine Rochet, Lionel Rigottier-Gois, Malene Sutren, Marie N. Krementscki, Claude Andrieux, Jean P. Furet, Patrick Taillez, Florence Levenez, Agnes Mogenet, Jean L Bresson, Severine Meance, Antony Leplingard, Joel ote In vivo Colonic Synthesis of Butyric Acid (BA) and M2117 Colonic Mucosal Cell Proliferation (CP) in Pigs Fed Lactulose (LACTUL) and/or Inulin (IN) C. L. Kien, Wendy L Frankel P enotes W Poster of istinction

7 POSTR SSSIONS--COMBIN SCINC M2118 M2119 Bovine Colostrum Ameliorates the Bacterial Translocation and Intestinal ndotoxemia in 5-FU Treated Rats Jeong Wook Kim, Woo Kyu Jeon, un Jeong Kim, Seung Sei Lee, Joon Sup Yeom, Hyo Soon Park, Myong Suk Shin, In Kyung Sung, Chung 11 Sohn, Byeong Kim, Hong Jin Min, Yong Kyun Cho, ong I1 Park Comparative valuation of Three ifferent Breath Test Substrates for Assessment of Orocaecal Transit Time in Healthy Volunteers Vicky e Preter, Tamara Coopmans, Anja Luypaerts, Karen Geboes, Kristin Verbeke SSAT Poster Session AM-5:00 PM Hall F OTHR/MISCLLANOUS A New Optical Method of valuating Tactile Sensation M2120 for Robotic Surgery: Use of 1Hb in the Analysis of Tissue Blood Flow Soji Ozawa, Junya Oguma, Yasuhide Morikawa, Toshiharu Furukawa, Masaki Kitajima Results of Primary Surgical Treatment of M2121 Gastrointestinal Stromal Tumors Pascal Bucher, Peter Villiger, Jean-Francois gger, Leo Buhler, Philippe Morel a Vinci Robotic Surgical xperience at a University M2122 Setting: First One Hundred Cases Brian Zebrowski, Sonja Kinney, Cori McBride, mitry Oleynikov oes the Pneumoperitoneum with CO2 Alter the Ultra- M2123 structuture of the Mesothelium? Marcos T.A. Rosario, Ulysses Ribeiro Jr., Carlos. P. Corbett, Alberto Ozaki, Claudio Bresciani, Bruno Zilberstein, Joaquim J. Gama-Rodrigues Squamous Cell Carcinoma of Anal Canal - A Changing M2124 ntity in ra of HIV isease? Rabi Kundu, Franco Niccini, avid Henry, Scott Fisher, eborah Nagle, Susan Gordon Changing Trends in lliopsoas Abscess M2125 ennis K. Schimpf, Krishnan Raghavendran, Rebecca Read, Muhamad Kulaylat iagnosing Cancer with Untreated Fresh Lymph Node M2126 and Surgical Specimens of Gastrointestinal Tract Using Contact Microscope Method Hitoshi Satodate, Haruhiro Inoue, Shin-l Kudo Robotic Assisted Laparoscopic Surgery M2127 Sergio Rojas-Ortega, Luis Sanchez enotes W Poster of istinction P-201

8 POSTR SSSIONS--BASIC SCINC S i~t ii Y < MAY 18 AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a p~orit.y as you visit the poster session. AM-5:00 PM Hall F BILIARY PHYSIOLOGY, TRANSPORT CHOLANGIOCYT BIOLOGY, XPRIMNTAL CHOLSTASIS Molecular Identification of a Novel Gene ncoding T905 Human Organic Cation/Adriamycin Transporter OCAI: A New Transporter which Mediates the Cellular Influx of Adriamycin in Cancer Cells Mitsunori Okabe, Michiaki Unno, Koh Miura, Takayuki Mizoi, Seiichi Ishii, Kenichi Shiiba, lwao Sasaki Comprehensive Study of the ffects of Rifampicin and T906 Ursodeoxycholic Acid on Genes and Proteins Involved in Regulation, Transport and etoxification of Biliary Compounds in Gallstone Patients Harms-Ulrich Marschall, Martin Wagner, Gernot Zollner, Peter Fickert, Judith Gumhold, agmar Silbert, Ulf iczfalusy, Lisbet Benthin, Rosita Grundstrom, Staffan Sahlin, Curt inarsson, Michael Trauner Human MRP1 Mediates ATP-dependent Transport of T907 Unconjugated Bilirubin (UCB) Igino Rigato, Lorella Pascolo, Cristina Femetti, onald J. Ostrow, Claudio Tiribelli Bilirubin (BI) Protects Plasma Membrane from Osmotic T908 Stress but Increases Bile Salt (BS) etergency: Implications in Cholestasis Piero Portincasa, Antonio Moschetta, Michele Petruzzelli, Michele Vacca, M. Krawczyk, Giuseppe Palasciano Cystic Fibrosis Mice Have an Impaired Capacity to T909 ilute Their Bile, Leading to Increased Cytotoxicity Frank A. J. A. Bodewes, Marcel J. C. Bijvelds, Rick Havinga, Juul Bailer, Hugo R. de Jonge, Henkjan J. Verkade Non-Obese iabetic Mice Have Shortened Biliary T910 Crystal Observation Time Shannon J. Graewin, Keun-Ho Lee, James M. Kiely, Carol L. Svatek, Attila Nakeeb, Henry A. Pitt Alpha Adrenergic Antagonist Indoramin Increases T911 Gallbladder Motility in Subjects with Gall Stone isease Subhasish Sengupta, Prasenjit Modak, Noreen MacCawley, Ronan Waldron, Luke J.. O'onnell Clarithromycin Increases Gall Bladder mptying in Both T912 Normal Subjects and in Subjects with Gall Stone isease Subhasish Sengupta, Prasenjit Modak, Noreen MacCawley, Ronan Waldron, Luke J.. O'onnell StAR5, a Liver Related START omain Protein, Binds T913 Both Cholesterol and Oxysterols, and Markedly Increases Cellular Cholesterol Content Following Overexpression in Primary Rat Hepatocytes aniel Rodriguez-Agudo, Shunlin Ren, Phillip Hylemon, alila Marques, Seema Gupta, Antonio del Castillo-Olivares, Gregorio Gil, William M. Pandak BASIC SCINC The Anionic Polypeptide Fraction Is Present on the T914 Gallbladder Apical pithelium and Favours Biliary Cholesterol Absorption Stefano Ginanni Corradini, Francesca Liguori, Nicole omingo, Giovanni Tebala, Cristina Ripani, Rosanna e Marco, Maria Siciliano, Maria Assunta Meini, Paulette Lechene dela Porte, enis Lairon, Huguette Lafont, Adolfo Attili istinct Quantitative Trait Loci (QTL) etermine High- T915 ensity Lipoprotein (HL) Cholesterol Levels and Cholesterol Gallstone Formation in Crosses of the Inbred Mouse Strains PRA/i, with l/lnj and BA/2J Henning Wittenburg, Malcolm A. Lyons, Renhua Li, Gary A. Churchill, Joachim Mossner, Martin C. Carey, Beverly Paigen ifferences in Bile Acid and Cholesterol Metabolism in T916 Mice xpressing the Human Rather Than the Mouse CYP7AI Gene Allen Cooper, Sung-Joon Lee, Jean Chen Prolactin Regulates, by an Autocrine Mechanism, T917 Cholangiocyte Proliferation Through Ca2+/PKC - ependent Activation of Src/Raf-1/RK1/2 SilviaTaffetani, Heather Francis, Shannon Glaser, Julie Venter, Ramona Reichenbach, Luca Marucci, Jo Lynne Phinizy, Giammarco Fava, Antonio Benedetti, Gianfranco Alpini Translational Regulation of XIAP Mediates Survival of T918 Malignant Human Cholangiocytes uring Hypoxia Carla Marienfeld, Yoko Yamagiwa, Valorie Chiasson, Linda Brooks, Fanyin Meng, Tushar PateI ATP-ependent Regulation of Biliary Secretion Through T919 P2X4 Purinergic Receptors Tom Matzakos, Sylene Goodwin, Gregory Fitz, Brian octor Cholangiocyte Infection by Rhesus Rotavirus Results in T920 Chemokine xpression Which May be the Initiating vent in Biliary Atresia Steven R. Allen Sr., Bryan onnelly, Jorge Bezerra, Richard Ward, Greg Tiao ffect of Calcium on Volume Activated Chloride T921 Current in Mouse Cholangiocyte Biyi Chen, Grant. Nicol, Won Kyoo Cho ndogenous Opioids Inhibit Cholangiocyte Proliferation T922 in the BL but not in the Normal Rat Marco Marzioni, Gianfranco Alpini, Stefania Saccomanno, Luciano Trozzi, Shannon Glaser, Giampiero Macarri, Antonio Benedetti Susceptible Role and istinct istribution of ph T923 Members in Cholangiocyte Koji Fukushima, Yoshiyuki Ueno, Noriatsu Kanno, Yuki Moritoki, Jun lnoue, Tooru Shimosegawa lntracellular Calcium Has a Permissive Role in T924 Regulatory Volume ecrease in Mouse Cholangiocytes Won Kyoo Cho, Vicki Siegrist Histamine Stimulates Cholangiocyte Proliferation T925 Through Transduction Pathways Involving the HI and H2 Histamine Receptor Subtypes Heather Francis, Silvia Taffetani, Shannon Glaser, Julie Venter, Jo Lynne Phinizy, Ramona Reichenbach, Giammarco Fava, omenico Alvaro, Luca Marucci, Antonio Benedetti, Marco Marzioni, Gianfranco Alpini P-202 ~ enotes W Poster of istinction

9 POSTR SSSIONS~BASIC SCINC T926 Neuropeptide Y (NPY) Inhibits Cholangiocarcinoma Growth by Interaction with a G-protein Coupled Receptor by Ca 2+ ependent Modulation of Src/RK1/2 Phosphorylation Giammarco Fava, Shannon Glaser, Heather Francis, jo Lynne Phinizy, Julie Venter, Ramona Reichenbach, Silvia Taffetani, Marco Marzioni, Luca Marucci, Antonio Benedetti, Gianfranco Alpini A Nuclear Receptor Ligand own-regulates Cytosolic T927 Phospholipase A2 (cpla2) xpression to Reduce bile Acid-induced Cyclooxygenase 2 (COX-2) Activity in Cholangiocytes: Implication of Anti-carcinogenic Action of Farnesoid X Receptor (FXR) Agonist aisuke Komichi, Susumu Tazuma, Tomoji Nishioka, Hideyuki Hyogo, Kazuhiko Tsuboi, Minoru Sakomoto, Keishi Kanno, Yoshihiro Numata, Atsushi Yamaguchi, Toshiya Kobuke, Michihiro Nonaka, Motoki Inoue, Keiko Iwamoto, Yoshitaka Nabeshima, Mami Watanabe, Kazuaki Chayama Microarray Analysis of Biliary Tract Obstruction T928 Hongtao Wang, Robert O. Heuckeroth MdrU- Mice with Sclerosing Cholangitis: A Model of T929 Chronic Cholestasis to Study the Role of the Adaptive Response of Hepatobiliary Transport Systems and Bile Acid Synthetic nzymes Gernot Zollner, Martin Wagner, Peter Fickert, Andrea Fuchsbichler, Judith Gumhold, agmar Silbert, Kurt Zatloukal, Grace L. Guo, Hanns-Ulrich Marschall, Helmut enk, Michael Trauner Melatonin Ameliorates Cholestatic Liver Injury in Rats T930 with Acute Obstructive Jaundice Afsar Barlas, Sebnem Tekin, ilek Bangir, Scrap Arbak, Goksel Sener, Cumhur Yegen, Berrak C. Yegen ffect of Peroxisome-Proliferator Agonist Receptor-alpha T931 (PPAR-alpha) and -gamma (PPAR-gamma) on Hepatocellular Organic Cation Uptake by S1c22all (Oct1) Seth R. Sweetser, Richard M Green AASL Poster Session AM-5:00 PM Hall F CLL AN MOLCULAR BIOLOGY, STM CLLS Keratin 8 And 18 Over-xpression Is Not a Prerequisite T932 for Mallory Body Formation and Pancreatic Injury Ikuo Nakamichi, iana M. Toivola, Sara A. Michie, Helene Baribault, Robert G. Oshima, M. Bishr Omary Site-Specific Inhibition of Keratin Phosphorylation in T933 Transgenic Mice Alters the Regulation of Multiple Hepatocyte Cellular Proteins Nam-On Ku, Jian Liao, Gurmil Gendeh, Jay Lorch, M. Bishr Omary T934 T935 T936 SOCS1 Is a Suppressor of Liver Fibrosis and Hepatitisinduced Carcinogenesis Takafumi Yoshida, Akihiko Yoshimura, Michio Sara The Role of Protein Phosphatase 1 in Human Hepatocellular Carcinoma Patrick Klein, Chad Wiesenauer, Jennifer Choi, C. M. Schmidt ffect of iabetes () on Rat Liver Fluid-Phase ndocytosis (FP) and Signal Transduction: Comparison to ffects of Cholera Toxin (CTX) Rebecca W. Van yke, Marianne R. Lewis Plasmid NA-based Gene Therapy of T937 Hyperbilirubinemia in Gunn Rats Istvan anko, Zhen Jia Thyl-Positive Mesenchymal Cell> Pronmte tile T938 Maturation of C49F-Positi~e tiepalic Progenihw ( ells in the Mouse Fetal Liver Toshitaka /Ioppo. I lidca]<i Fu]ii, To>tin, l lil-o,c. K,'~l.~r,, Yasuchika, Hisaya Azuma, Shinji lgal~& Maqato Naih, Takafumi Machimoto, ]wao Ikai Propranolol Increases Markers of Liver Injury and T939 Promotes Accumulation of Hepatic Oval Cells Jude A. Oben, Tania Roskam~, >tqicli Nang, Zhipi~g Ih HuiZhi Lin, Nicoletta Sinelli, Anna Mac iehl LL is an ssential Additive for Serum Free Culture of T940 Fetal Hepatic Stem Cells Amit Shukla, Ian S. Currie, Neff M. Masson, Rosey A. L. Bayne, Olivier J. Garden, Rowan W. Parks, James A. Ross Treatment of Surgically Induced Acute Liver Failure by T941 Transplantation of HNF4-Overexpression mbryonic Stem Cells Xiao-Ling Kuai, Shu-ong Xiao Transplantation of Human Umbilical Cord Blood Cells T942 to Injured Liver Sei Kakinuma, Yujiro Tanaka, Kinji Asahina, Kentaro Okamura, Yoshinori Soeno, Chise Tateno, Katsutoshi Yoshizato, Kenichi Teramoto, Shigeki Arii, Naoya Sakamoto, Hirobumi Teraoka, Mamoru Watanabe AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders BACTRIAL FACTORS IN HLICOBACTR PATHOGNSIS Helicobacter pylori Urease Binds to C74 and Stimulates T943 Gastric pithelial Cell Responses Associated with Pathogenesis llen J. Beswick, avid Bland, Soumita as, Giovanni Suarez, Johanna Sierra, Victor. Reyes Helicobacter Pylori Outer Membrane Protein (HP1125) T944 Induces endritic Cell Maturation and Function Sivaprakash Rathtnavelu, John Kao, Yana Zavros, Juanita L. Merchant Fur- and Iron-responsive Gene Regulation of the T945 Helicobacter Pylori Superoxide ismutase Gene sodb Florian. rnst, Georg Homuth, rnst J. Kuipers, Jeroen Stool, Stefan Bereswill, Manfred Kist, Johannes G. Kusters, Arnoud H. M van Vliet The Presence of the Cag Pathogenicity Island Is T946 Associated with Increased ROS Scavenging by Helicobacter Pylori Raymond G. J. Pot, Jacco J. Briede, rnst J. Kuipers, Arnoud H. M. van Vliet, Jos C. S. Kleinjans, Johannes G. Kusters The H. pylori Periplasmic ol-carbonic Anhydrase Is T947 Required for Acid Survival avid R. Scott, lizabeth A. Marcus, Yi Wen, George Sachs Adhesin Function of the Outer Membrane Protein HorB T948 in the Human Gastric Pathogen Helicobacter Pylori William Shelling, Kieran Ryan, Paul W. O'Toole The NikR Protein Governs Transcriptional Regulation of T949 NixA-Mediated Nickel-Uptake in Helicobacter pylori Arnoud H. M van Vliet, Florian. rnst, rnst J. Kuipers, Angela Heijens, Jeroen Stool, Johannes G. Kusters enotes W Poster of istinction P-203

10 T U S A Y MAY 18 Purified Outer Membrane Proteins of Helicobacter pylori T950 Produce Interleukin-8 from Gastric pithelial Cells Hong Lu, Jeng Y. Wu, Takahiko Kudo, ong-hyeon Kwon, avid Y. Graham, Yoshio Yamaoka valuation of the Association Of Nine Helicobacter T951 Pylori Virulence Factors with Strains Involved in Low Grade Gastric MALT Lymphoma Philippe Lehours, Armelle Menard, Sandrine upouy, Bernard Bergey, Frederique Richy, Frank Zerbib, Agnes Ruskone-Fourmestraux, Jacques Tankovic, Jean-Charles elchier, Francis Megraud istinct iversity of the cag Pathogenicity Island of T952 Helicobacter Pylori in Japan Takeshi Azuma, Masahiro Ohtani, Akiyo Yamakawa, Shiho Yamazaki, Yukinao Yamazaki, Yoshihide Keida ffect of Lansoprazole on the Motility of H.Pylori - T953 xamination Using a Novel ark-field Image igital Analysis System Hidekazu Suzuki, Shuhei Nishimoto, Kumiko Kurabayashi, Yuka Abiko, Tatsuhiro Masaoka, Hiromasa Ishii Co-infection: Helicobacter pylori (Hp) / Human T954 Immunodeficiency Virus (HIV) Martin Olmos, Valentina Araya, Ana Fanin, Hugo Concetti, duardo Piskorz, duardo Coronado Quesad, Femando Magnanini Adhesion Molecules in Children with Helicobacter Pylori T955 (Hp) Gastritis in ifferent Stages of isease to 2 Strains of lip Vasundhara Tolia, P. Michael Long, Kim Boyer, angfei Wang, Ron Thomas, Raymond Podzorski Response of Murine and Human Gastric pithelial Cells T956 to Cag A-Positive and -Negative Strains of Helicobacter pylori Malini Basu, Thomas G. Blanchard, Steven J. Czinn Isogenic Variation of Helicobacter Pylori Strain Resulting T957 in Heteroresistant Antibacterial Phenotypes in a Single Host in vivo Sun-Young Lee, Yong Chan Lee, Jae J. Kim, Jae Hee Pyo, ong H. Kwon, Jong Chul Rhee Correlation Between Helicobacter pylori OipA Protein T958 xpression with oipa Gene Switch Status Takahiko Kudo, Zhannat Z. Nurgalieva, Margaret. Conner, Sue Crawford, Stefan Odenbreit, Rainer Haas, avid Y. Graham, Yoshio Yamaoka Scanning lectron Microscopic valuation of Interaction T959 Between Helicobactor pylori and AGS Cells Jin Hal Hyun, Rok Son Choung, Yong Sik Kim, Yoon Tae Jeen, Hoon Jai Chun, Hong Sik Lee, Soon Ho Urn, Sang Woo Lee, Jai Hyun Choi, Chang uck Kim, Ho Sang Ryu, Hye-Jung Min, un-kyung Park, Chang-Sub Uhm Helicobacter Pylori and Platelet Aggregation. Results of T960 Screening of 26 Bacterial Strains Paul A. Corcoran, ermot Cox, John C. Atherton, Stephen W. Kerrigan, Richard M. Peek, esmond J. Fitzgerald, Frank. Murray, Michael F. Byrne POSTR SSSIONS--BASIC SCINC AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders IMMUN RSPONS TO HLICOBACTR INFCTION Suppression of Lymphocyte Apoptosis at Low Levels of T961 H. pylori Infection Francoise Bussiere, Rupesh Chaturvedi, Justin Gainor, Adina Scholz, aniel Fertel, Michael Yao, ana Sloane, Yulan Cheng, Hangxiu Xu, Keith T. Wilson L-arginine Uptake Regulates H. pylori-induced T962 Macrophage inos Rupesh Chaturvedi, Francoise Bussiere, Preston Kim, Yulan Cheng, Hangxiu Xu, Robert A. Casero Jr., Keith T. Wilson Interleukin-2 Gene Polymorphisms Associated with T963 Increased Risk of Gastric Atrophy by Helicobcter Pylori Shozo Togawa, Takashi Job, Tadayuki Oshima, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, Nobuyuki Hamajima, Nobuyuki Katsuda, Hidemi Ito, Kazuo Tajima, Keitaro Matsuo, Makoto hoh Helicobacter Pylori Activates Nf-KB via both Classical T964 and Alternative Pathway in Murine and Human Peripheral Blood Mononuclear Cells Tomoya Ohmae, Yoshihiro Hirata, Shin Maeda, Wataru Shibat~, Ayako Yanai, Keiji Ogura, Haruhiko Yoshida, Takao Kawabe, Masao Omata The Fas Pathway Modulates Immunity uring T965 Helicobacter pylori Vaccination sther Galindo-Mata, Yaron Avitzur, Nicola Jones Humoral and Cellular Immune Response to H. pylori T966 Infection According to Age Gifone A. Rocha, Taciana F. Soares, Andreia M.C. Rocha, Anfrisina S.T. Carvalho, Paulo Bittencout, Celso A. Oliveira, Ana M. M. F. Nogueira, Rodrigo Correa-Oliveira, Ana M.C. Faria, Olindo A. Martins-Filho, Monica M..A. Cabral, ulciene M.M. Queiroz Recruitment and Activation of endritic Cells by T967 Helicobacter pylori Kathleen M. Anderson, Thomas G. Blanchard, Steven J. Czinn T968 IL-113 and IL-7 Levels in the Gastric Tissues Were Correlated to ~/8 T Cells Counts : levation of v8 2/v8 1 T Cell Ratio in Chronic Gastritis with Strong lga reponses to H. Pylori Urease Seiji Futagami, Tetsuro Hiratsuka, Kenji Suzuki, Masanori Kusunoki, Nobue Ueki, Yoko Shinji, Kei Shinoki, Hitoshi Nishigaki, Ken Wada, Kazumasa Miyake, Taku Tsukui, Kazushi Ohashi, Masumi Shimizu, Hidemi Takahashi, Katya Gudis, Choitsu Sakamoto AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology COLON CANCR: BASIC I Role of Inducible Nitric Oxide Synthase (NOS2) in T969 evelopment of Apoptosis Resistance in Colon Carcinogenesis Hana Holubec, Claire M. Payne, Harris Bemstein, Carol Bemstein, Katerina vorakova, Ronnie Fass, Harinder Garewal P-204 ~ enotes W Poster of istinction

11 POSTR SSSIONS~BASIC SCINC T970 Rebamipide Inhibits Gastric Cancer Cell Growth via Induction of Cyclin-ependent Kinase lnhibitors p21 and p27: Possible Involvement of Smad Signaling Pathway Tetsuya Tanigawa, Rama Pal, Tetsuo Arakawa, Andrzej S. Tarnawski Cyclooxygenase-2 (COX-2) Gene xpression and T971 Prostaglandin Production Is ecreased in Human Adenocarcinoma Cells After Treatment with Physiological oses of icosapentaenoic Acid Grace Lee, lizabeth K. Lund, Yong Ping Bao, Michael Rhodes, Ian Johnson The Role of PPAR"/in Colon Carcinogenesis, and Its T972 Relation to 13-Catenin Nobutaka Fujisawa, Masato Yoneda, Hirokazu Takahashi, Takako Yoshii, Atsushi Nakajima, Nobuyuki Matsuhashi Butyrate Sensitization of Gastric and Colon Cancer T973 Cells to the Growth inhibitory ffect of GF-Receptor Related Protein (RRP) Udayini Kodali, Richard Jaszewski, Adhip P. N. Majumdar Cox-2 Inhibition by Celecoxib Is Not Sufficient to T974 Induce Apoptosis or Inhibit Cell proliferation in Human Colon Carcinoma Cell Line Shahar Lev-Ari, iana Kaznov, Ludmila Strier, Hadas vory-sobol, Liora Madar-Shapiro, ov Lichtenberg, Nadir Arber AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology GASTRIC CANCR: BASIC Identification of Gastric Cancer Patients by Serum T975 Protein Profiling Matthias bert, Jorn Meuer, Jan Wiemer, Stephanie Lamer, Thomas Buschmann, Volker Seibert, Ulrich Traugott, Hans- Ulrich Schulz, Marc Reymond, Peter Malfertheiner, Christoph Roecken Clustering of Overexpressed Genes in Chromosomal T976 omains in GJ Carcinomas Natalie Koon, Alexander Zaika, Christopher Moskaluk, Steven Powell, Henry F. Frierson, Wa'el l-rifai A p53 Genetic Polymorphism of Gastric Cancer: T977 ifference Between arly Gastric Cancer (GC) and Advanced Gastric Cancer (AGC) Sun Young Yi, Han Hyo Lee, Jun Sik Nam, Moon Sun Yeom, un Jung Lee, Sung-Ae Jung, Ki-Nam Shim, Hye- Kyung Jung, oe-young Kim, Yoo Kwon, I1-Hwan Moon iagnosis of Malignancy and Benign Alterations in T978 Gastric Biopsy Specimen by mrna xpression Profiling and Multivariate Statistical Methods Orsolya Galamb, Ferenc Sipos, Bela Molnar, Zsolt Tulassay Gastric Cancer and Multidrug Resistance: oes COX2 T979 and PgP Play a Role? Alba Rocco, Rosario Caruso, Luciana Rigoli, Laura Ottini, Renato Mariani-Costantini, Gerardo Nardone ysregulation of Calcium Signaling Molecules in Gastric T980 Cancer Narendra Sankpal, Alexander Zaika, Henry F. Frierson, Steven Powell, Wa'el l-rifai Hypermethylation Status Around xon 1 of XIAP- T981 Associated Factor 1 in Human Gastric and Colon Cancer Cell Lines Bing Zou, Marrie C. M. Lin, S. K l.am, ShuiPing I u. YI Yang, Jide Wang, Hua He, Jun Zhong Pcng, H. F. Ktmg. Benjamin C. Y. Wong Mutation Analysis of hsmad2 Gene in Gastric Adcnoma T982 Byung Kyu Park, Kyung Hwa Park, Sun A. Kim, Sung Pll Hong, Hye Won Chung, Seung Woo Park, Jae-Bock Chu*/g. Han-Soo Kim, Si Young Song ecreased Adhesion of Human Gastric Cancer Cells to T983 Vascular ndothelial Cells by Introduction of Human N- Acetylgalactosaminyhransferase Which Forms Carbohydrate Antigen xclusively xpressed in Normal Gastric Fundic Mucosa Yuki I. Kawamura, Ryuko Fukunaga, Rei Kawashima, Taeko ohi Helicobacter Pylori xpress an 2a Homologue? T984 Barbara Ada Manzo, Ian R. Sanderson, James W. Wilson T985 p27 ~api Regulates the Apoptotic Response of Gastric pithelial Cells to Helicobacter Pylori Hidetoshi guchi, Sung Soo Kiln, Stephanie Carpemier, Steven F. Moss Cyclooxygenase-2 Modulated Cyclin ~, Cyclin- T986 dependent Kinases (Cdks) and Promoted Cell Cycle Progression in Gastric Tumor Growth Stimulated by Nicotine Vivian Y. Shin, Yi-Ni Ye, Marcel W. L. Koo, Chi-Hin Cho IL-6 May Prevent Submucosal Invasion in a Mouse T987 Gastric Cancer Model by Augmenting Leucocyte Infiltration Meegan Howlett, Louise M. Judd, Brendan Jenkins, Matthias rnst, Andrew S. Giraud Inhibition of Gastric Cancer-associated Angiogenesis by T988 Cox-2 Inhibitor or Anti-sense cna Yuan-Gen Fu, Joseph J. Y. Sung, Kai-Chun Wu, Han-Pin Wu, ai-ming Fan, Wai K. Leung Gastric Neoplasia in CH-1 Knockout Mice Using N- T989 methyl-n-nitrosourea Carcinogenesis: A Murine Model of Hereditary iffuse Gastric Cancer Vanessa Blair, Amanda Charlton, Iain G. Martin, Parry Guilford Resveratrol Bypasses Mitochondrial Signals to Initiate T990 Apoptosis in Gastric Adenocarcinoma Cells William L. Riles, Bashar M. Attar, Oksana Holian T991 Potent Inhibition of Cell Growth and Angiogenesis in Gastric Cancer by Small Interference RNA for Cydooxygenase (COX)-2 Kai-Chun Wu, Li-Ping Yao, Tao-Zhi eng, Han-Ping Wu, Yang-Lin Pang, ai-ming Fan Gastric Cancer: ifferential xpression of Genes Inside T992 the RBB2 Amplicon Alexander Zaika, Asta Varis, Sakari Knuutila, Christopher Moskaluk, Wa'el 1-Rifai enotes W Poster of istinction P-205

12 POSTR SSSIONSmBASIC SCINC U S A Y MAY 18 AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONS/TRANSMITTRS/RCPTORS AN TH NTRIC NRVOUS SYSTM Nitric Oxide Generation by Ghrelin and Localization of T993 GHS-R in the Rat Stomach Tatsuro Tanaka, Hisayuki Uneyama, Sumio Yoshie, Kunio Torii Galanin Receptor Messenger RNAs are xpressed in T994 ifferent Regions of the Rat Gastrointestinal Tract Laura Anselmi, Arlene Hirano, Salvatore Stella Jr., Nicholas C. Brecha, Marcello Tonini, Carla Sternini CRFI Receptors Mediate xcitatory Actions of Urocortin T995 on Neurons in Guinea-Pig Small Intestinal Myenteric Plexus Sumei Liu, Hong-Zhen Hu, Na Gao, Guo-u Wood, Xi-Yu Wang, Xiucai Fang, "fun Xia, Jackie. Wood Interleukine(I1)-8 Secretion by nteric Neurons: T996 vidences from Cell Lines and Coculture xperiments Using Human nteric Neurons mmanuelle Tixier, Michel Neunlist, Paul-Antoine Lehur, Jean-Paul Galmiche Role of Glutamate- N-methyl--Aspartate (NMA) T997 Receptors in Neuronal Plasticity and Gastrointestinal Transit elay Induced by Ischemia/Reperfusion in Rats Francesco Calcina, lisabetta Barocelli, Simona Bertoni, Fiore Cattaruzza, Vigilio Ballabeni, Mariannina Impicciatore, Catia Sternini xpression of Two Isoforms of Tryptophan Hydroxylase T998 (TpH-1 And TpH-2) in the Human and Mouse Gut Jason J. Chen, Shilin Wan, Michael. Gershon Visualization and Mapping of Mechanosensitive P2X T999 Receptors in the Human BON - nterochromaffin Cell Model Jacqueline. Wunderlich, Jianjing Xue, Helen J. Cooke, Fievos L. Christofi Capsaicin-induced Ca 2+ Increase in Myenteric Plexus of T1000 Guinea Pig Small Intestine Are Mediated by xtrinsic Fibers Giovanni Samelli, Raf Bisschops, Petra Raeymaekers, Pieter Vanden Berghe, Jozef Janssens, Jan Tack ~2-Adrenoceptors Couple to Inhibition of R-type T1001 Calcium Channels in Myenteric Neurons in Guinea-Pig Ileum Xiaochun Bian, James J. Galligan 5-HT4 Receptor Agonists Facilitate Fast xcitatory T1002 Synaptic Potentials uring Trains of Stimulation in the Myenteric Plexus Jim Ren, James J. Galligan AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONS/TRANSMITTRS/RCPTORS: SIGNALLING PATHWAYS AN MOLCULAR PHARMACOLOGY PKC-o, -~ and RHO/ROK-MIAT PKC-vt Activation T1003 Modulates Phorbol ster-mediated Neurotensin Secretion in a Human ndocrine Cell Line Jing Li, Kathleen L. O'Connor, Leoncio A. Vergara, Mark R. Hellmich, George H. Greeley Jr., Courtney M. Townsend Jr., B. Mark vers Identification of the G Protein-ependent Signaling T1004 Pathways Mediating Motilin-lnduced Smooth Muscle Contraction Jiean Huang, Huiping Zhou, Sunila Mahavadi, John R. Grider, Karnam S. Murthy Receptors Coupled to Inhibitory G Proteins Induce T1005 MLC20 Phosphorylation and Muscle Contraction via PI 3-Kinase-ependent Activation of Integrin-Linked Kinase (ILK) Karnam S. Murthy, Jiean Huang, Huiping Zhou, John F. Kuemmerle, Gabriel M. Makhlouf The 3-Ubiquitin Ligase C-Cbl Regulates Protease- T1006 Activated Receptor 2 (PAR2) Claire Jacob, Graeme Cottrell, Fabien Schmidlin, ileen F. Grady, Nigel W. Bunnett Investigation of the Role of Tyrosine Phosphorylation in T1007 Oxidative Stress-Induced Protein Kinase Activation in Swiss 3T3 Fibroblasts Richard T. Waldron, Osvaldo Rey, lena Zhukova, nrique Rozengurt PACAP Regulates via the PAC1 Receptor Internalization T1008 and Signal Transduction in Jurkat, a Human Model of T Lymphocytes Patrizia Germano, Sandy Lieu, avid S. Oh, Sang Le, Joseph R. Pisegna Synergistic COX-2 xpression by Ang and GF in IC- T cells Lee W. Slice, nrique Rozengurt Molecular Basis for the Selectivity of the Mammalian T1010 Bombesin Peptide, Neuromedin B (NMB) for Its Receptor Tomoo Nakagawa, Kenji Tokita, Tatsuro Katsuno, Michael Schumann, Samuel A. Mantey, Robert T. Jensen elineation of the Motilin omain Involved in T1011 esensitization and Internalization by Using Full and Partial Antagonists Anna Mitselos, Inge epoortere, Theo Peeters Sequential Binding of SHP-2 to ~V~3 Integrin, SHP-2 T1012 substrate-1 (SHPS-1) and IGF-I Receptor etermines the xtent of IGF-I Receptor Activation John F. Kuemmerle, Jennifer G. Bowers Attenuation of Cyclic GMP Levels by Contractile T1013 Agonists Is Caused by Inhibitory Phosphorylation of Soluble Guanylyl Cyclase (sgc) Mediated by RhoAdependent Inhibition of Phosphatase-1 (PP1) Karnam S. Murthy, Art Sitaramayya, Gabriel M. Makhlouf Kinome Profiling for Studying Signal Transduction T1014 Klaartje Kok, Sander iks, Tom O'Toole, aan Hommes, Peter Van ijken, Jos Joore, Maikel Peppelenbosch P-206 ~ enotes W Poster of istinction

13 r POSTR SSSIONS~BASIC SCINC T1015 T1016 T1017 T1018 T1019 T1020 T1021 T1022 Bombesin Rapidly Stimulates Focal Adhesion Kinase Phosphorylation at Ser-843 by an Increase in Intracellular Calcium Concentration Robert S. Fan, nrique Rozengurt GF Receptor Transactivation Mediates Neurotensin- Stimulated MAP Kinase Activation and I1-8 Gene xpression in Human Colonic pithelial Cells ezheng Zhao St., Hon-Wai Koon Sr., Huiyan Zeng, Charalabos Pothoulakis PACAP Stimulates Signal Transduction and Proliferation in the BON Neuroendocrine Tumor Cell Line, Via Coupling to Signaling Pathways Mediated by Gaq Patrizia Germano, avid Oh, Jianjing Xue, Sandy Lieu, Alan Siu, Sang Le, Helen Cooke, Joseph R. Pisegna The Full Length Progastrin Peptide (rhpg1-80) xerts Anti-Apoptotic ffects on Pancreatic Cancer Cells via Progastrin Receptors (PG-R): Signaling Pathways William Rengifo-Cam, Pomila Singh Pharmacological Manipulation of Angiotensin 1I and Transforming Growth Factor Beta 1 in Mesothelial Cells Arnold C. Goede, Kevin M. Sales, Korsa Khan, Martyn. Caplin, Marc C. Winslet Characterization of Mechanisms Accounting for COX-2- Mediated Proliferative Actions of Gastrin on Human Colon Cancer Cells Rocchina Colucci, Corrado Blandizzi, Cristina Vassalle, Marzia Tanini, Narcisa Ghisu, Maria Cristina Breschi, Mano el Tacca Src Phosphorylation and Kinase Activity nhanced by Transient xposure to PP2 Steven S. Wu, nrique Rozengurt Signaling Pathways Contributing to Colonic Mucosa Hyperproliferation in Transgenic Mice Overexpressing Progastrin or Glycine-xtended Gastrin Audrey Ferrand, Claudine Bertrand, Ghislaine Portolan, Guang-Lin Cui, Jane Carlson, Lucien Pradayrol, aniel Fourmy, Marlene ufresne, Timothy Wang, Catherine Seva AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB: ANIMAL MOLS: FUNAMNTAL MCHANISMS T1023 T1024 T1025 T1026 Inhibition of Caspase-Mediated Keratin egradation in Transgenic Mice Prevents SS-Induced Colitis Nam-On Ku, M. Bishr Omary Keratin 8 eficient Mice as a Unique Ulcerative Colitis Model Aida Habtezion, iana M. Toivola, ugene C. Butcher, M Bishr Omary The Protective ffect of Group I1A Secretory Phospholipase A2 (spla2) in Murine SS-Induced Colitis Is COX-2 ependent Jian Zhong, Munira Nasser, Meredith Bostrom, Nancy R. Webb, Willem J. S. de Villiers LFA-1 eficient T-Cells Fail to Induce Chronic Colitis in an Immune-Based Mouse Model Kevin P. Pavlick, mitry V. Ostanin, F. S. Laroux, Laura Gray, John H. Chidlow Jr., Sulaiman Bharwani, Christopher G. Kevil, Matthew B. Grisham T1027 T1028 T1029 T1030 T1031 T1032 T1033 T1034 T1035 T1036 T1037 T1038 T1039 A New Model of Chronic Colitis in SCI Mice Induced by Adoptive Transfer of C4+GITR T kymphocytes Takanori Kanai, Koji Uraushihara, Tertlji q'ot~uka. Shin Makita, Ryoichi Iiyama, Tetsuya Nakamura, Mamoru Watanabe C45RBhigh C4+ T Cell Screening of Peptides erived from a cna xpression Library Generated from C45RBhigh C4 + T Cell Transfcrred Colitic RagKO Animals Reveals Potentially Novel Antigens Victor M. Morales, Chen Ma, Rice Wilbon, Lawrence J Saubermann Immunoproteasome Induction in a Lymphocyte Cell Line and in Mice with extran Sulfate Sodium-Induced Colitis Leo R. Fitzpatrick, Vineeta Khare, Walter A. Koltun Role of Adhesion Molecules in the Recruitment of T- Lymphocytes and Platelets uring extran Sulfate (SS)-Induced Colitis Mikiji Mori, Thorsten Vowinkel, James W. Salter,. Nell Granger Pathogenic C4+ T Cell Responses to Commensal Luminal Bacteria in HLA-B27 Transgenic Rats with Chronic Colitis Are Mediated by both MHC Class II and HLA-B27 Molecules Bi-Feng Qian, Susan L. Tonkonogy, R. Balfour Sartor efective Ability of HLA-B27 Transgenic Rats to ownregulate Antigen Specific T Cell Responses to Commensal Luminal Bacteria and to Respond to Immunosuppressive IL-10 Bi-Feng Qian, Susan L. Tonkonogy, Frank Hoentjen, Levinus A. ieleman, R. Balfour Sartor L-selectin and MAdCAM-1 Are Required for the Maintenance of Chronic Ileitis in the SAMP1/YitFc-SCI C4 T Cell Transfer Model of Crohn's isease (C) J~sus Rivera-Nieves, Anthony Bruce, Giorgos Bamias, Timothy Olson, Tracy Burcin, Sharon Hoang, Theresa T. Pizarro, Fabio Cominelli, Klaus F. Ley Helicobacter cineadi Induced Typhlocolitis in IL-10 ~" Mice Zeli Shen, Yan Feng, Michelle emarco, Zhongming Ge, Shilu Xu, Arlin B. Rogers, Mark T. Wary, Samuel R. Boutin, James G. Fox Carbon Monoxide Ameliorates Colitis in T-Cell Receptor-or (TCR or) eficient Mice Refaat Hegazi, Aqila Mayle, Antonia Sepulveda, Leo Otterbein, Scott Ple W Colitis in Mice Infected with an Attaching and ffacing Bacterial Pathogen Is Associated with Somatic Mutations in C57BL/6 Mice Jane J. Sohn, Lynn L. Ngo, Arlin B. Rogers, James G. Fox, avid B. Schauer IL-12 and T-Cells in the hfut1 Transgenic Mouse Model of Colitis Steven J. Brown, Greg Moore, Ashley Miller, Sally Bell, William Connell, Ross lliott, Paul esmond, avid Vremec, Peter Cowan, Tony d'apice Impaired Nf-kB Signaling as Potential Susceptibility Factor for xperimental Colitis Yingzi Cong, Jason Beckwith, dward H. Leiter, Robert M. Hershberg, Charles O. lson Induction of Colonic Fibrosis in Mice by Intramural Gene Transfer of Monocyte Chemoattractant Protein-1 Yasuaki Motomura, Waliul I. Khan, Rami T. l-sharkawy, Jack Gauldie, Stephen M. Collins enotes W Poster of istinction P-207

14 POSTR SSSIONS--BASIC SCINC T1040 T1041 T1042 T1043 T1044 T1045 T1046 T1047 T1048 T1049 T1050 T1051 T1052 T1053 STAT1, STAT4, and T-bet xpression Modulate the Transition from arly to Late xperimental Colitis in IL-10 eficient (IL-104J Mice avid M Spencer, liot M. Bourk, Sarah A. avies, Pingfu Fu, Alan. Levine Adoptive Transfer of Non-transgenic Mesenteric Lymph Node Cells Induces Inflammation in Athymic HLA-B27 Nude Rats Frank Hoentjen, Susan L. Tonkonogy, R. Balfour Sartor, Levinus A. ieleman Interaction Between Carbon Monoxide and Nitric Oxide in the Intestinal Inflamed Mucosa of extran Sulfate Sodium-Treated Mice Yuji Naito, Tomohisa Takagi, Kazuhiro Katada, Hisato Tsnboi, Toshimitu Okuda, Hiroshi lchikawa, Satoshi Kokura, Norimasa Yoshida, Takeshi Okanoue, Toshikazu Yoshikawa ffect of Interferon Alpha in extran Sulfate Sodium Induced Colitis in Mice Irfan Soykan, Murat Toruner, Arzu nsari, them Gecim, Sahin Coban, Hulya Cetinkaya, Ali Ozden Signal Transducer and Activator of Transcription (Stat)- 1 Is detrimental in SS Induced Acute Inflammation Sudip K Bandyopadhyay, Carol A. de la Motte, Scan P. Kessler, Scott A. Strong LIGHT/LTAB2/LTBR/HVM Interactions nhance C4 + T Cell Alloresponses in MHC Class II isparate MLC and GVH Geri R. Brown, dward L. Lee, Jihad M. 1-Hayek, Katherine M. Kinmer, Cheryl Luck ndogenous Substance P (SP) Is Involved in the tiology of Inflammation and Abnormal Motility of the Colon in a Rat Model of Ulcerative Colitis Shinya Kishimoto Osteopenia in the hfut1 Transgenic Mouse Model of Colitis Natalie Simms, Steven J. Brown, Greg Moore, Kong Wah Ng, Peter Cowan, Tony d'apice oes a Surgical Insult Lead To Altered Immune Tolerance Of Bowel Flora in IL-10 eficient Mice? Robert Penner, Beate Sydora, Michele Tavernini, Jason oyle, Richard Fedorak Colonic Mucosal Inflammation in a Murine TNBS Model of Colitis: Role of Chemokines and PCAM-1 Naohito Sugimoto, Osamu Handa, Gediminas Cepinskas, Peter Kvietys Phenotypic Analysis of NKT, NK, and T Cells in an NSAl-Induced Model of Colitis in IL-10 KO Mice Victor Arrunategui-Correa, Joel Weinstock, Hyun Sil Kim Induction of Inflammatory Bowel isease Accelerates Adenoma Formation in MIN Mice mina H.N. Huang, Juliet Park, Henry Appelman, Alan Weinberg, Craig. Logsdon, Ann Marie Schmidt ffects of Varying ietary Fatty Acids on Chronic Colitis, Colitis-Associated Colon Neoplasia and COX-2 xpression in IL-10 KO Mice Hossam M. Kandil, Refaat M. Hegazi, Reda Saad, Hussam Mady Up-Regulation of Matrix Metalloproteinase-9 in a Rat Model of Chronic Colitis Carlos Medina, Alfredo Santana, Maria Cristina Paz-Cabrera, Federico iaz-gonzalez, nrique Quintero T1054 T1055 T1056 T1057 The Role of Cryptopatch-erived Intraepithelial Lymphocytes in the evelopment of Chronic lleocecitis Shin Makita, Takanori Kanai, Satoshi Matsnmoto, Koji Uraushihara, Teruji Totsnka, Tetsuya Nakamura, Mamoru Watanabe In vitro and in vivo Studies into the Interaction of Reactive Oxygen Species with Colonic Mucus Iain A. Brownlee, John Knight, Jeff P. Pearson Uterine Motor Alterations and Ovarian Cycle isturbances After TNBS-induced Colitis in the Rat ric Houdeau, Muriel Larauche, Lionel Bueno, Jean Fioramonti ecreased, but Not Increased, Mucosal Permeability Correlates with the evelopment of extran Sulfate Sodium-Induced Colitis in Rats Kei Matsueda, Masayuki Uchida, Keiko Morikubo, Seiko Namshima, Hajime Ariga, Tomofumi Amano, Hirotsugu Uehara AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders MUCOSAL IMMUNOLOGY T1058 T T T T1062 T1063 T1064 TGF-I3 Induces a Regulatory Phenotype in C4 + C25- T Cells Through FoxP3 Induction and ownregnlation of Smad7 Massimo C. Fantini, Christoph Becker, Giovanni Monteleone, Francesco Pallone, Peter R. Galle, Markus F. Neurath eficient IL-12 Signal Transduction / STAT4 Phosphorylation in Whipple's isease Sabine Ring, Rene Mahnel, Anja Kah, Thomas Schneider, Andreas Stallmach, Gerhard Feurle, Thomas Marth IRF-1 and IRF-2 istinctively Up-Regulate Gene xpression and Production of IL-7 in Human Intestinal pithelial Cells Shigeru Oshima, Tetsuya Nakamura, Shin Namiki, Takanori Kanai, Mamom Watanabe Increase of Bone Marrow-erived Secretory Lineage Cells uring pithelial Regeneration Following Graft- Verses-Host isease in the Human Intestinal pithelia Tomoko Matsumoto, Ryuichi Okamoto, Tomoharu Yajima, Tetsuya Nakamura, Takanori Kanai, Toshifumi Hibi, Mamoru Watanabe lnterleukin-21 (IL-21) nhances TH1 Cell Signaling and Interferon-gamma Production in Crohn's isease Giovanni Monteleone, Ivan Monteleone, aniele Fina, Piero Vavassori, Giovanna el Vecchio Blanco, Thomas T. Maconald, Francesco Pallone Interactions of Mucosal Lymphocytes with the xtraceflular Matrix (CM) Component Fibronectin (FN) Iris otan, Sharon Vigodman, Lena Broitman, Hagit Tulchinsky, Talia Abram, Nitsan Maharashak, Alexandra Zhanin-Zorov, Iris Hecht, Zamir Halpern, Ofer Lider Peyer's Patch-Independent Induction of Allergic Sensitization to a Model Food Antigen in Mice Cecilia Berin, Jens Brimnes, Jianhua Liu, Peter Boros, Lloyd Mayer P enotes W Poster of istinction

15 v POSTR SSSIONS--BASIC SCINC T1065 T1066 T1067 T1068 T1069 T1070 T1071 T1072 T1073 T1074 T1075 T1076 T1077 xogenous IL-2 Is Required to lucidate the Regulatory ffect of C4+C25 + T cells on the evelopment of Colitis Yasuyo Shimomura, Ype P. de Jong, Svend T. Rietdijk, miko Mizoguchi, Ken Sugimoto, Masaru Yoshida, Richard S. Blumberg, Cox Terhorst, Atul K. Bhan, Atsushi Mizoguchi Intracellular Redox quilibrium in the Intestinal Lamina Propria T Cell (LPT) Tunes the T Cell Receptor (TCR) Signaling Cascade Brenda M. Rivera Reyes, Silvio anese, Miquel Sans, Claudio Fiocchi, Alan. Levine Primary Isolated Human Colonic Myofibroblasts xpress B7 Family Ligands that Regulate ffector and Memory T Cells Jamal I. Saada, Carlos A. Barrera, Patrick A. Adegboyega, Irina V. Pinchuk, Radha A. Tamerisa, Randy C. Mifflin, John F. imari, Victor. Reyes, on W. Powell ominant Role for TLIA/R3 Pathway in IFN-'y Production from Cytokine-Primed Peripheral Blood (PB) and Mucosal CCR9+ T Cells Konstantinos A. Papadakis, aocheng Zhu, John Prehn, Carol Landers, Stephan R. Targan The nteric Nervous System and Innate Immunity Ove Lundgren, Jessica Fennander, Lennart Svensson Immunomodulatory Role of IL-4 on Regulatory T Cells in vitro and in xperimental Colitis Philippe Maerten, Chong Shen, Gert Van Assche, Karel Geboes, Paul Rutgeerts, Jan Ceuppens endritic Cell (C) Control of Lymphocyte Homing: C4 + T-cells Activated by Human Colonic C xpress High Levels of o 4[~7 Integrin Rachael J. Rigby, Steila C. Knight, Michael A. Kamm, Ailsa L. Hart, Andrew J. Stagg Upregulation of a Mechanism That Inhibits NF-KB Activation uring ifferentiation of Intestinal Macrophages (IMAC) Katja Schreiter, Martin Hausmann, Werner Falk, Hans Herfarth, Juergen Schoelmerich, Gerhard Rogler endritic Cells (C) Are Present in Human Omentum but Increase in Number and Lose MHC Class It Antigen in Crohns isease Penelope A. Bedford, Vesna Todorovic, Nicholas R. nglish, dward. A. Westcott, Alistair C. J. Windsor, Kankipati S. Raju, Stella C. Knight The Role of C2 and C28 in Oral Tolerance Christine G. Moung, Jens Brimnes, Jimmy Ko, Lloyd Mayer Potential Gut-Homing [~7-Integrin+ Human Blood endritic Cells (C) Produce Lower Levels of IL-10 and IL-12 Than Their [37- Counterparts Rachael J. Rigby, Stella C. Knight, Michael A. Kamm, Andrew J. Stagg The Pivotal Role of I1-7/I1-7r-ependent Signaling Pathway for xpansion of Highly ll-7r xpressing Mucosal T Cells and evelopment of Chronic Colitis riko Okada, Motomi Yamazaki, Tetsuya Nakamura, Takanori Kanai, Masanobu Tanabe, Tsutomu Takeuchi, Mamoru Watanabe Inhibition of M Cell Formation by eletion of the Chemokine Receptor CCR6 Andreas Luegering, Martin Floer, Christian Maaser, Thomas W. Spahn, Ifor R. Williams, Wolfram omschke, Torsten Kucharzik T1078 In vivo Homing and Proliferation of OVA-specific C4 + C25 + T Cells and Prevention of Colitis Occur, in the Absence of Cognate Antigen Pengfei Zhou, Rajka Borojevic, Kenneth Croitoru AM-5:00 PM Hall F Morid[ Conv('~lil~n (Tt'ntt'l Sponsored by: Motility & Nerve-Gut Interaction ION CHANNLS IN TH GASTROINTSTINAL TI~-\CT Participants will be able to: Attendees will learn about the types of ion channels expressed by neuronal and non-neuronal cells in the gastrointestinal tract; Attendees will learn about the function of ion channels in neuronal and non-neuronal cells in the gastrointestinal tract; Attendees will learn about the molecular mechanisms regulating ion channel expression in the gastrointestinal tract. Protease-activated Receptor 2 (PAR2) Sensitizes the TI079 Capsaicin Receptor TRPV1 to Induce Hyperalgesia Silvia Amadesi, Jingjiang Nie, Nathalie Vergnolle, Graeme S. Cottrell, ileen F. Grady, Marcello Trevisani, Chiara Manni, Pierangelo Geppetti, James A. McRoberts, John B. avis, meran A. Mayer, Nigel W. Bunnett Increased xpression of the Capsaicin Receptor TRPV1 T1080 in the Inflamed Human sophagus Philip Matthews, Qasim Aziz, Paul Facer, John avis, avid Thompson, Praveen Anand etection of Mechanosensitive Ion Channels and T1081 Associated Proteins in Vagal Visceral Afferent Neurones of the Mouse Using RT-PCR Lei Zhang, Sarahlouise Jones, Marcello Costa, Simon J. H. Brookes Acid-voked Calcitonin Gene-Related Peptide (CGRP) T1082 Release from Cultured Primary Sensory Neurons Is Amiloride-Sensitive but Not Mediated by the Vanilloid Receptor (TRPV1) Willemijntje A. Hoogerwerf, Bryan Kosler, Mohan Shenoy, John Winston, Pankaj J. Pasricha Negative Transcriptional Regulation of L-Type Calcium T1083 Channels by p50 and p65 Subunits of NF-KB in Human Colonic Circular Smooth Muscle Cells Xuan-Zheng Shi, Konrad Pazdrak, Nehad I. Saada, Bosong ai, Philip T. Palade, Sushil K. Sarna Intermediate Conductance Calcium-Activated Potassium T1084 Channels (IK) in Mouse and Human nteric Neurones Inger-Sofie Selmer, Craig B. Neylon, Kulmira Nurgali, Kate Keamey, Mao X. Chen, Stephen. Moore, John B. Furness R-Type Calcium Channels in Myenteric Neurons of T1085 Guinea-Pig Small Intestine Xiaochun Bian, James J. Galligan Identification of a Non-selective Cationic Current in T1086 Isolated Smooth Muscle Cells from Guinea Pig Gallbladder Georgi V. Petkov, Mark T. Nelson, Gary M. Mawe A Majority of Neurons xpressing Nay1.3 in the Guinea T1087 Pig Myenteric Plexus Also xpress nnos Huijun Yan, Aaron Bartoo, Leslie K. Spmnger, avid A. Schneider T1088 ffects of VR1 Receptor Antagonism on Responses to Intestinal istension in the Rat Wendy Winchester, Charlotte Booth, Pam Gaskin, John avis, Harshad Rami, Gareth Hicks enotes W Poster of istinction P-209

16 T U S A Y MAY 18 T1089 T1090 T1091 T1092 Nay 1.9 but Not 1.8 Current Is Augmented in RG Neurons Innervating the Viscera 3-5 Weeks After Transient Inflammation of Mouse Jejunum Wolfgang Kunze, Jiahui Lin, Andrzej Stanisz, Ronald de Hoogt, Pieter Peeters, Jeroen Aerssens, Ann Meulemans, Bernard Coulie, avid Grundy, Ronald H. Stead Vanilloid Receptor 1 (VR1) Immunoreactivity (IR) in the Human Gastrointestinal (GI) Tract Inger-Sofie Selmer, Roxane Peddle, laine Fraser, John MacKinnon, Wendy Winchester, Graham Smith, Robert H. Riddell, Ronald H Stead lntestinofugal Afferent Neurons in the Guinea Pig istal Colon Are Mechanosensory and Utilize NaC-Like Proteins Leonid G. rmilov, Steven M. Miller, Gianrico Farrugia, Joseph H. Szurszewski Multiple Voltage-Gated Na + Channel ~ Subunit lsoforms Are xpressed in the Small and Large Intestine Aaron Bartoo, avid A. Schneider, Leslie K. Sprunger POSTR SSSIONS--BASIC SCINC P enotes W Poster of istinction

17 POSTR SSSIONS~CLINICAL SCINC CLINICAL SCINC AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pro. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F WASH - CLINICAL AN PIMIOLOGY T1093 T T1095 T1096 T1097 T1098 T1099 Tll00 TllO1 Tl102 Population Prevalence of Pediatric Fatty Liver isease Tanaz Kahen, Jeffrey Schwimmer, Joel Lavine, Christina Stanley, Cynthia Behling Histological Predictive Factors in Patients with Pure Fatty Liver Sanne am-larsen, Maria Franzmann, Per Christoffersen, Klaus Larsen, Ulrik Becker, Flemming Bendtsen Small Bowel Bacterial Overgrowth Is Highly Prevalent in Patients with Morbid Obesity but Is Not Associated with NASH Florence Hamois, Jean Marc Sabate, Charlotte Mechler, Simon Msika, Cecile Poupardin, Maggy Grossin, Benoit Coffin The ffects of Weight and Lifestyle Changes on Hypertransaminasemia in Nonalcoholic Fatty Liver isease: A Longitudinal Study Ayako Suzuki, Flavia Mendes, Keith Lindor, Ayako Muto, Toshihide Okada, Paul Angulo A Revision of the Brunt System for Grading the Activity of Non-alcoholic Steatohepatitis Masoud Sotoudeh, Seyed-Mohamrnad Tavangar, Farzaneh Kbadem-Samani, Mohammad-Hossein erakhshan, Shahin Merat, Reza Malekzadeh Comparison of Paired Liver Biopsies in Morbidly Obese Subjects with Nonalcoholic Fatty Liver isease Gary A. Abrams, Nirag Jhala, Audrey Lazenby, Sachin Kunde, Teresa Leath, Brian Raglan& Ronald Clements Hepatic ATP Levels and Steatosis in Obese Patients with Type 2 iabetes Steven F. Solga, Jeanne M. Clark, Alena Horska, Charalett iggs, Thomas Shields, Frederick Brancati, Anna Mac iehl The Role of the Glucose Challenge Test in the valuation of Patients with Non Alcoholic Fatty Liver isease Krikor Kichian, Alice Gerhardt, Klaus Gutfreund, Laurence Jewell, Mang Ma, Andrew Mason, Leanne Mulesa, Winnie Wong, Vincent Bain Antoantibodies in Overweight Adults with Type 2 iabetes and Hepatic Steatosis Michel I. Kafrouni, Jeanne M. Clark, Steven F. Solga, Charalett iggs, Thomas Shields, Alena Horska, Frederick L. Brancati, Anna Mac iehl iabetes but Not Obesity Is Associated with Advanced Fibrosis in Patients with Non Alcoholic Fatty Liver isease Srinivasan asarathy, Shankar Thiruppathi, Milan odig, Yao Liu, Amer Khiyami, Mary Petrelli, Kevin. Mullen, Arthur J. McCullough Tl103 Tl104 Tl105 Tl106 Tl107 Tl108 Tl109 Tlll0 Tl111 Tl112 Tll13 Tl114 Tl115 Hepatic xpression of Leptin in Patients of Non- Alcoholic Fatty Liver iseases (NAFL) Kyoko Okumura, Kenichi Ik~\jhna. Shunli Matsumuto. Shunhei Yamashina, Toru Fukuda. Nobu\ uki [{nomott~. Satoko Suzuki, Tsuneo Kitamura, Yoshiyuki Tal<ci, Nobuhiro Sato Nonalcoholic Steatohepatitis veith Insulin Resistance Can be Associated with Unexplained Creatine Kinase levations Sudhanshu Gogia, lizabeth M. Brunt, Brent A. Neuschwander-Tetri Obstructive Sleep Apnea in Patients with Non-Alcoholic Fatty Liver isease Harminder Singh, Richard Pollock, Meir Kryger, Gerald Y. Minuk The Prevalence of Nonalcoholic Fatty Liver isease on Liver Biopsy in Patients with an Unexplained levation of Aminotransferases over Ten Year Period Tamer N. Sargios, Gopal Narasimhan, Radhakrishna Kalakuntla, avid J. Clain, Henry C. Bodenheimer Jr., Albert. Min Factors Associated with Nonalcoholic Fatty Liver isease in Patients Presenting for Roux n-y Gastric Bypass Surgery Amir R. Alkhuraishi, Jeanne M. Clark, Steven F. Solga, Michael Torbenson, Alireza Tabesh, Michael Schweitzer, Anna Mac iehl, Thomas H. Magnuson Tracking a Possible Serologic Marker of NASH Presence Giovanni Tarantino, Paolo Conca, Paolo Sorrentino, Paola Ragucci, Manuela Ariello (~linical and Histological Features of Non-alcoholic Fatty Liver isease in Chinese Vincent W.S. Wong, Henry L. Y. Chan, Alex Y. Hui, Kui F. Chan, Choong-Tsek ew, Francis K. L. Chan, Joseph J. Y. Sung Characteristics of Hepatocellular Carcinoma in Cryptogenic Cirrhosis: A Case-Control Study Makoto Taniguchi, Yukinaga Yoshida, Takamasa Ohki, Hiroki Matsumoto, Hayato Nakagawa, Michiharu Seki, Nobuo Toda, Kazumi Tagawa The Impact of Therapy with Rosiglitazone (RSG) Versus Metformin (MT) on Liver Associated nzymes (LAs) in Patients with Type 2 iabetes Mellitus Kendell Mann, Brian Mulhall, Corinne Maydonovitch, erek Stocker, Robert Vigersky, Kent Holtzmuller A Pilot Trial of Pentoxifylline in Nonalcoholic Steatohepatitis Leon A. Adams, Claudia O. Zein, Keith. Lindor, Paul Angulo Non Alcoholic Fatty Liver isease (NAFL) in Severely Obese Subjects: emographic, Biochemical and Metabolic Correlates of isease Severity Pierre M. Gholam, Louis Flancbaum, ouglas A. Chamey, Steven Reinert, onald P. Kotler Incidence and Improvement Factors of Nonalcoholic Fatty Liver isease in Japanese Tadashi Yoshida, Yasushi Matsuzaki, Sayoko Shidara, Kazuto Ikezawa, Itoe Makino, Takahisa Shiraishi, Susumu Koseki, Naomi Tanaka Hepatic MRI for Fat Quantitation: Its Relationship to Fat Morphology, iagnosis and Ultrasound Sailaja M. Cheruku, Mark H. Fishbein enotes W Poster of istinction P-211

18 T U S A Y MAY 18 Tll16 Tll17 TlI18 TlI19 Tl120 Tl121 Tl122 valuation H63 Mutation and Hepatic Iron Content in Turkish Patient with Non-alcoholic Steatohepatitis Hale Sumer, Halls Simsek, ngin Yilmaz, Yasemin H. Balaban, Cenk Sokmensuer, Gokhan Gedikoglu, Gonca Tatar valuation of Patients with levated Alaninaminotransferases (ALT) in the VA Population John B. Rodgers, Christine Pocha, Kevin Gaylord, Benedict Maliakkal Prevalence and Indicators of Portal Hypertension in Nonalcoholic Fatty Liver isease Flavia. Mendes, Ayako Suzuki, Paul Angulo efinition of a Normal ALT: Locally stablished Normal Ranges etermine the Upper Limit of Normal Without Accounting for Overweight or Obesity Brent A. Neuschwander-Tetri, NIK NASH Clinical Research Network Comparison of the Outcome of NAFL Stratified by the Stage of Fibrosis and the Platelet Count Hiroyuki Kaneda, tsuko Hashimoto, Yoko Yoshioka, Makiko Taniai, Katsutoshi Tokushige, Keiko Shiratori Health-Related Quality of Life in Patients with NASH Jessica A. Smith, Brent A. Neuschwander-Tetri Hepatocellular Carcinoma in Obese Non-HBV, non-hcv, and Non-cirrhotic Patients Jean-Frederic Blanc, Christophe Laurent, Antonio Sa Cunha, Steven Nobili, Maylis Capdepont, Herve Trillaud, Brigitte Le Bail, Victor e Ledinghen, Jean Saric, Charles Balabaud, Paulette Bioulac-Sage AM-5:00 PM 0 Sponsored by: AGA; Liver and Biliary CLINICAL HPATITIS: MANAGMNT T1123 Tl124 T1125 Tl126 POSTR SSSIONS--CLINICAL SCINC Hall F Magnetic Resonance Imaging (MRI) nhanced with Superparamagnetic Iron Oxide (SPIO) for Assessing Liver Function ikuo Nagashima, Tadahiro Takada, Kota Okinaga, Koichi Takada, Koji Takeshita, Shigeru Furui Generation of Neutralizing Antibodies, ScFv, for HCV l/2 Complex Using Antibody Phage isplay Technique Chung JungMyung, Jung MyungKyo, Seol SangYoung, Lee SangHyuk, Park untaek, Park SungJae, Park SaeGwang, Choi InHak ouble-blind Randomised Study of Steroids in Acute Uncomplicated Cholestatic Non-B Non-C Hepatitis Aabha Nagral, Smita Nalawade, Perin Notani, Priya Nisar, Umesh Algal Hepatitis C Therapeutic Management Patterns Among Gastroenterologists in the United States: A National Survey Scan P. Hurley, Matthew Hepburn, Michael Russo, ric Lawitz Tl127 Tl128 Tl129 Tl130 T1131 Tl132 Tl133 Tl134 Tl135 Tl136 Tl137 Induction-ose of PG-Interferon Alfa-2b in Combination with Ribavirin in HCV-Non-Responders to Prior Interferon or lnterferon-ribavirin Combination Therapy: Results of a French Multicenter RIBAPG-NR Trial Isabelle Rosa, Herve Hagege, Veronique Auray-Cartier, Philippe Cassan, Claire Wartelle, Jacques enis, Jean Pierre Arpurt, Olivier Nouel, any Gargot, Bernard Nalet, Alex Pariente, Michel Chousterman, RIBAPG-NR Study Group ifferences in Physicians' Recommendations Regarding Over-The-Counter Analgesic Use in Patients with Chronic Liver isease Monica B. Awsare, Victor J. Navarro, Stanton Smullens, Barbara Turk, ouglas rake, Steven K Herrine Clinical Study of Autoimmune Hepatitis Associated with Bile uct Injury Resembling Chronic Non-Suppurative estructive Cholangitis Bon Shoji, Yoshiaki Iwasaki, Yasuhiro Miyake, Kohsaku Sakaguchi, Yasushi Shirarori Reduced Liver Necrosis and Fibrosis and Improved Liver Functions in a CCl4-1nduced Hepatitis Model by ReishiMax Supplementation Wen-Chuan Lin, Yue-Wen Wu, Ming-Chun Xie, Jia-Shi Zhu Treatment of Chronic Hepatitis C with Pegylated Interferon alfa-2a plus Ribavirin in Hemophiliac Patients Reza Malekzadeh, Shahin Merat, Amir A. Sohrabpour, Siamak Khaleghi, Katakyoun Samimi-Rad Risk Factors and Long-term volution of Thyroid ysfunction uring Repeated Antiviral Treatments in 221 Patients with Chronic Hepatitis C Xavier Moncoucy, Florence keymarie, Stephane Levy, Brigitte Bernard-Chabert, amien Jolly, Brigitte elemer, Guillaume Cadiot, Marie-aniele iebold, Gerard Thiefin Catholic University xperience with MARS epurative System in Patients with Severe Liver Failure Lorenzo Zileri dal Verme, Rita Gaspari, Michele C. Santoro, Filippo Gargano, Rodolfo Proietti, Giovanni Gasbarrini, Antonio Gasbarrini xperience with Pegylated Interferon and Ribavirin Therapy for Hepatitis C Patients with Compensated Cirrhosis in an Urban VA Hospital Abhinandana Anantharaju, Linda Piersall, JoAnn Stegmaier, Bernard Nemchausky, Frank Iber, Nikunj Shah Use of an Office-based 2-Question Instrument for etecting epression in Hepatitis C Patients avid H. Winston, onna C. Winston Interferon-based Therapy of Chronic Hepatitis C in Adults with a History of Treated Malignancy Maya Gambarin-Gelwan, Nancy Lau, Sara H. Olson, Sumera awood, Hans Gerdes, Robert C. Kurtz Hepatitis B Virus Genotypes and Mutations in the Precore and Core Promoter Regions in Patients on Hemodialysis and from the Community Zaigham Abbas, Rana Muzaffar, Afsheen Raza, Arif Siddiqui, Anwar Naqvi, Adibul H. Rizvi P-212 ~ enotes W Poster of istinction

19 POSTR SSSIONS~CLINICAL SCINC AM-5:00 Sponsored by: Clinical Practice Hall F practic MANAGMNT/QUALITY ASSURANC The Impact of an vidence Based Lecture and Clinical T 138 Prompt on the Rate of Colorectal Cancer Screening by Internal Medicine Residents Kenneth A. Seres, Angela C. Kirkpatrick, William M. Tierney Institutional Interventions Significantly Reduce IV Tl139 Pantoprazole Prescribing rrors Gilaad G. Kaplan, awn Mconald, uane Bates, Joseph Romagnuolo Iron and Vitamin B12 Status in Patients on Long-Term Tl140 Treatment with Proton Pump Inhibitors inar Bjornsson, Niklas Mattsson, Magnus Simren, Pia Agerforz, Hasse Abrahamsson, Anders Kilander fficacy of Lansoprazole 15 mg in the on emand Tl141 Treatment of Gastro sophageal Reflux Hassani Zahir, Vrijens Bernard, Bigard Marc Andre Guidelines Have No Impact on Appropriate Usage of Tl142 I.V. Pantoprazole Michelle M. Lipman, Sameer Barkatullah, Nora Flint, Ali Keshavarzian, ce A. Mutlu Inadequate Use of Acid-Suppressive Therapy in Tl143 Hospitalized Patients and Its Implications for General Practice Raffaella Scagliarini, lena Magnani, Angelo Zelante, Renato Bocchini, Antonino Pratico', Paolo Pazzi High Gastrointestinal Symptom Burden in Patients Tl144 Using Proton Pump Inhibitors Ulla ells Moss, Arlders Carlsterl, inar Bjornsson Are Proton Pump Inhibitors NIC or Not? Tl145 Mazin R. Aljabiri, ebbie Grant, T. F. Chan, Steve Mann, Niall varlsomeren, Kalpesh Besherdas Withdrawal of Proton Pump Inhibitors in Patients on T1146 Long-Term Therapy inar Bjornsson, Magnus Simren, Niklas Mattssonl Pia Agerforz, Hasse Abrahamsson, Anders Kilander Ineffective sophageal Motility Is a Possible Marker of Tl147 sophageal Pathologic Acid xposure Ji Hyang Kim, Poong-Lyul Rhee Validation of the Supraesophageal Reflux Questionnaire Tl148 (SRQ) ileen H. auer, ana M. Thompson, Teresa Zais, G. Richard Locke III, Jeffrey A. Alexander, Alan R. Zinsmeister, Shamina hiilon, Ross ierkhising, Ann Harris, Kaiser Lim, Kenneth Offord, dythe Strand, James Wise, Yvonne Romero Tl151 Tl152 Tl153 Tl154 Tl155 Tl156 Tl157 Tl158 Tl159 Tl160 TI161 Impact of the Rockall Risk Scoring System (Rrss) in the Management and Prognosis of High Risk Upper Gastrointestinal Bleeding (UGIB) Not Related to Portal Hypertension Bessa Xavier, lena O'Callaghan, Balleste Belch, Nieto Miquel, Seoane Agustin, Panades Agusti, Andreu Mcmtse, Bori Felipe Impact of ndoscopic Ultrasonography (US) and US- Fine Needle Aspiration (FNA) oll tile Management of Patients with Cancer of the sophagus and Gastroesophageal Junction Angels Gines, Stephen. Cassivi, James.\ Marten>on.-\l.m R. Zinsmeister, Claude eschamps, Mark S. Alien, J. F. Quevedo, Frank A. Sinicrope, Joseph A. Murray, Cathy Schleck, Steven R. Alberts, Robert C. Miller, Michael G. Haddock, Francis C. Nichols III, nrique Vazquez- Sequeiros, Teresa Zais, Yvonne Romero Factors Influencing The Hospital Length Of Stay After Percutaneous ndoscopic Gastrostomy (PG) Uma Kantamneni, Ajit Kokkat, Mario Ricci, Hatef Massoumi, Nejat Kiyici, dward Norkus, HilaiT Hertan Management of Low and High Grade ysplasia (LG and HG) in Inflammatory Bowel isease (IB): A Gastroenterologists' Perspective and Current Practice in UK Titus Thomas, Prakash Nair, Mike W. ronfield, John F. Mayberry Poster Presentations at National and International Gastroenterology Conferences Are of Limited Value Peter Irving, Sarah Lean, Andrew J. Wood, Stuart A. Mconald, dward M. Seward, avid S. Rampton ifference in Mortality After Surgery for Colorectal Cancer Thomas N. Nickelsen, Torben Jorgensen, Ole Kronborg?~nal Bleeding: A French Population Survey Laurent Siproudhis, Olivia Morio, Le Grep Steroid-Induced Osteoporosis Prevention in a Tertiary GI Clinic: Room for Improvement Michelle T. Thiny, Paul vans, Robert S. Sandler, Lisa M. Gangarosa Quality of Care for Out-Patients with IB: oes It Matter Where They Are Seen? Joel. Mawdsley, Peter Irving, Louise Langmead, mma Greig, Gai T Mackenzie, avid Rampton Patient-irected Follow-up of IB - A Successful Teamwork Jorgen Tholstrup, Miroslaw Wielondek, Woiciecb Broda, Martin Rejler Physician Awareness and Management of Osteoporosis in Patients with Inflammatory Bowel isease Arlil K. Sharma, Anthony Infantolino, Cuckoo ChoudhaiT, Franz Goldstein, Nora Sandorfi, Anthony J. imarino Jr., Sidney Cohen = Tl149 High Prevalence of Gastrointestinal Symptoms in Patients with Chronic Obstructive Pulmonary isease Anna Niklasson, Magnus Simren, Hans Strid, inar Bjornsson Tl150 Upper GI Bleeding in Canada: and avid G. Morgan, Jennifer Belbeck, Mark Lee enotes W Poster of istinction P-213

20 T U S A Y MAY 18 AM-5:00 PM Hall F ~1~ Sponsored by: sophageal, Gastric and uodenal isorders YSPPSIA Tl162 Tl163 TLI64 Tl165 Tl166 Tl167 Tl168 Tl169 Tll70 Tl171 Tl172 Tl173 The Influence of 5-HTIA Agonist on the Proximal Stomach Function in Healthy Volunteers Guy Boeckxstaens, Guido Tytgat, wa Wajs, Luc Van Nueten, Filip e Ridder, Jan Tack lectroacupuncture Accelerates Solid Gastric mptying in Patients with Functional yspepsia Sanping Xu, Hui Zha, Xiaohua Hou, J.. Z. Chen More Severe Symptoms of yspepsia Are Associated. with elayed Gastric mptying Gervais Tougas, Juif Jen, Gregory Ligozio, Marielle Cohard- Radice, avid arnest The Relationship Between Transit Parameters and GI Symptom Complexes G. Richard Locke III, Michael Camilleri, Rebecca Kendall, Alan Zinsmeister, Nicholas J. Talley Validation of the Reflux isease Questionnaire (RQ), a New Symptom Scale for Use in Patients with Upper Gastrointestinal Symptoms Sander J. O. Veldhuyzen van Zanten, Ingela Wiklund, Robert White, Bijan Chakraborty, avid Armstrong, Alan Barkun, Lisa Tanser, Krista Nevin Validation of a yspepsia Symptom Rating Scale Through Assessment of Patient-Observer Agreement Combining Results from Interview and iary Ratings Lone G. Madsen, Jane M. Hansen, Anette arholdt, Mogens Groenvold, Peter Bytzer The Impact of Unrecognized Anxiety on Health-Related Quality of Life in Patients with Functional yspepsia Sang-Wook Kim, Sang-Yeol Lee, Suck Chei Choi, Geom Seok Seo, Joo Jin Yeom, Yong Sung Kim, Young Woo Sohn, Tae Hyeon Kim, Yong-Ho Nah arly Impairment of Gastric Myoelectrical Activity in Type 1 iabetes Assessed with Muhichannel lettrogastrography Clelia Verde, Lisa Faiella, Giovanni Annuzzi, Angela Rivellese, Francesco e Giorgi, Gabriele Budillon, Rosario Cuomo The Long-term Natural History of yspepsia, and the Importance of the Irritable Bowel Syndrome Alexander C. Ford, avid Forman, Anthony T. R. Axon, Paul Moayyedi Is mpirical Proton Pump Inhibitor Useful in the Management of Young yspeptic Patients with Negative Urea Breath Test? Wai K. Leung, Justin C. Y. Wu, Sara S. L. Fung, Lawrence C. T. Hung, Vincent W. S. Wong, Aric J. Hui, Francis K. L. Chan, Joseph J. Y. Sung Gastric Infusion of HCI ls a Novel Test for yspepsia Sheila Rodriguez-Stanley, Sattar Zubaidi, Susan Riley, Philip B. Miner Jr. Community yspepsia: Somatization or isorder of Sensory and Motor Functions?. Janet Castillo, Michael Camilleri, G. Richard Locke III, uane Burton, ebra Stephens, ebra Geno, Alan Zinsmeister POSTR SSSIONS--CLINICAL SCINC Tl174 Tl175 Tl176 Tl177 Tl178 Tl179 Tl180 Tl181 Tl182 Tl183 Cost-ffectiveness of a "Score And Scope" Strategy for the Management of yspepsia Barenys de Lacha Merce, Garcia-Altes Anna, Abad Lacruz Agueda, Rota Rosa Selection of the Most Suitable rug for Patients with Chief Complaint of Upper Abdominal Symptoms at First Hospital Visit: Comparison of Ranitidine, Omeprazole, and TJ-43: Rikkun-shi-to Akinori Koide, Taketo Yamaguchi, Hidehiko Koyama, Takeo Odaka, Yoshihiro Koma, Kenichi Nakajima, lzumi Shinbo, Hitoshi Maeda, Masato Ai, Yoshihiro Tokoro, Hiromitsu Saisho Increasing Relevance of Sorbitol Malabsorption and Impact of iet in the ifferential iagnosis of yspeptic Symptoms and IBS Peter Janetschek, Fredericke Gantert Chronic Gastritis Is Not Associated with Abnormal lectrogastrogram or Gastric mptying in Children with yspepsia Craig A. Friesen, Zhiyue Lin, Robert Garola, Linda Andre, Ann Moore, Nancy Burchell, Charles C. Roberts, Richard W. McCallum Heterogeneity of yspepsia in the General Population in Belgium Hubert Piessevaux, Benedicte e Winter, Jan Tack, douard Louis, Vinciane Muls, anny e Looze, Paul Pelckmans, Michel ehenre, aniel Urbain Validation of the Gastrointestinal Symptom Score (GIS) in Patients with Functional yspepsia Gerald Holtmann, Birgit Adam, lisabeth Grote, Khaschayar Saadat-Gilani, Bettina Vinson Course of Symptoms in Functional yspepsia After Hp radication: A Prospective Long-Term Follow-up Nicoletta Stefani St., Nadia al Bo', Giulia M. Cavestro, Marta Maino, Veronica Iori, Lucas Cavallaro, Vincenzo Corrente, Andrea Maini, Bastianello Germana', Gioacchino Leandro, Alberto Pilotto, Giovanni Aragona, Angelo Franze', Francesco i Mario fficacy of Lansoprazole in the Acute Treatment of Non- rosive Reflux isease and Functional Ulcer-Like yspepsia AIun L. Cooper, Garth Baxter High Prevalence of Gastrointestinal Functional isorders in Women Reporting omestic Violence and Abuse to the Police Monica Perona, Ruth Benasayag, Antonia Perello, Javier Santos, Natalia Zarate, Patricia Zarate, Fermin Mearin Symptomatic Response to Blocked and Unblocked Pentagastrin Stimulation of Gastric Acid Secretion in Functional yspepsia - Comparison of Random Starting ay Trial (RS-trial) Responders and Non-responders Lone G. Madsen, Peter Bytzer AM-5:00 PM Hall F ~ Modal Convention Center Sponsored by: sophageal, Gastric and uodenal isorders GASTROUONAL ISORRS The Utility of AP-1 Gene Analysis of Human Gastric Tl184 CL Cell Carcinoid Tumors to efine Gastrin- Autonomy and etermine Tumor Subtypes Mark Kidd, Michael Shapiro, Shrikant Mane, Irvin Modlin P-214 ~ enotes W Poster of istinction

21 POSTR SSSIONS--CLINICAL SCINC Tl185 Tl186 Tl187 T1188 Tl189 Tl190 Tl191 Tl192 T1193 Tl194 Tl195 Tl196 Tl197 Tl198 H. Pylori (HP) radication Therapy vs. Antisecretory Non-radication Therapy for the Prevention of Recurrent Bleeding (RB) from Peptic Ulcer (PU): A Cochrane Systematic Review Javier P. Gisbert, S. Khorrami, F. Carballo, Xavier Calvet, mili Gene,. ominguez-munoz, J. M. Pajares Peptic Ulcer isease (PU) in a istrict General Hospital: Three ecades of Change Karna ev ev Bardhan, Christine Royston Increasing Annual Trend of Helicobacter Pylori-Negative Cases Among Patients with Peptic Ulcer isease uring the Last ight Years Hye-Kyung Jung, Yoon Ju Na, Ki-Nam Shim, Sung-Ae Jung, Sun Young Yi, oe-young Kim, Kwon You, I1-Hwan Moon Polymorphisms of Pro-inflammatory Cytokine Genes and Progression of Intestinal Metaplasia Associated with H. pylori Infection Joseph J. Y. Sung, Ka To, Martin Chan, nders K. W. Ng, Wai K. Leung Regional Three-imensional Geometry and Function of Stomach in iabetic Rats Jingbo Zhao, onghua Liao, Hans Gregersen A Prospective Randomized Study of Relapse in Peptic Ulcers on Maintenance Therapy with cabet + Ranitidine or Ranitidine Alone for 5 Years Wasaburo Koizumi, S. Tanabe, Katsuhiko Higuchi, N. Nakayama, M. Azuma, Katsunori Saigenji Is Travel to a eveloping Country a Risk Factor for Helicobacter pylori Infection? Holly B. Clark, Bona S. Christison, evon Hale, Mae F. Go ffect of Intravenous Application of Omeprazole 20 mg vs Omeprazole 40 mg vs Pantoprazole 40 mg on 24 Hour Intragastric ph in Male Healthy Adults irk Hartmann, ieter Schilling, Juergen F. Riemann Opposing Time Trends in the Prevalence of uodenal Ulcer and Reflux sophagitis in a Multiracial Asian Population Rosaida Md Said, Khean-Lee Goh H. Pylori and Perforated Peptic Ulcer. Prevalence of the Infection and Role of Non-Steroidal Anti-Inflammatory rugs Javier P. Gisbert, J. Legido, I. Garcia-Sanz, J. M. Pajares iagnosis of Malignancy in Gastric Ulcers Mukul Mehra, Gary R. Zuckerman, Chandra Prakash 13C-Acetate Breath Test for the etection of Intestinal Metaplasia in the Stomach Yoshibisa Urita, Yoshinori Kikuchi, Kazuo Hike, Naotaka Torii, iko Kanda, Hidenori Kurakata, Masahiko Sasajima, Kazumasa Miki Mt 21-42: evelopment and Validation of an Innovative Automatic evice Performing Gastric Juice Analysis (ph and Ammonium) uring ndoscopy Antonio Tucci, Primiano Tucci, Attilio Marchegiani, Giovanni Papadopoli, Pietro Fusaroli, Thomas Togliani, Francesca Jaboli, Alessia Spada, Massimo Oliviero-Pistoletto, Mauro Oliviero-Pistoletto, Giancarlo Caletti Atrophic Gastritis as a Cause of Hyperhomocysteinemia Luca Santarelli, Maurizio Gabrielli, Filippo Cremonini, Marcello Candelli, nrico C. Nista, Cristiano Lauritano, Rosalba Finizio, Paolo Pola, Giovanni Gasbarrini, Antonio Gasbarrini Tl199 T1200 T1201 T1202 T1203 Randomized Comparison of Gastric ph Control ~x ith Ranitidine, someprazole and Pantoprazolc for Stress Ulcer Prophylaxis in Critically 111 Patients Behzad Kalaghchi, Mohammad Ghandi, Mohammad L Hoque, Todd Henderson, R George Adam>, AI\iH \ Thomas, uane T. Smoot Recovery of Gastric Funclion After H. Pjhwi radication in Subjects with Body Atrophic Gastritis: A Prospcctixc Four Years Study Ali M. Moussa, Nadia a/ Bo. gucas G. Cavalhuo, Plctt,, Caruana, Giovanni Aragona, Giulia M. Ca\ c>tlo. \ crot~it:x lori, Roberta Merli, 5imone Bosi, Marino \7~'racrilo. Giancarlo Colla, Alberto Pilotto, Angelo Franzc, Flanccb~.o i Mario Gastroduodenal Opportunistic Infections and HIVassociated Malignancies in HIV + Patients with yspepsia in the ra of HAART Ana Luiza Werneck-Silva tiology and Histological Behavior of Gastric and uodenal Ulcers. Is Houston Consensus Applicable? Carlos Robles Mt 21-42: An Innovative Automatic Medical evice Identifying Helicobacter Pylori Infection and Atrophic Gastritis uring ndoscopy Antonio Tucci, Primiano Tucci, Attilio Marchegiani, Giovanni Papadopoli, Michele Bisceglia, Pietro Fusaroli, Thomas Togliani, Francesca Jaboli, Alessia Spada, Antonio Villani, Mario Marinelli, Giancarlo Caletti AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders NON-RFLUX SOPHAGAL ISORRS T1204 T1205 T1206 T1207 T1208 Immunological Characterization of osinophilic sophagitis: Allergen-Specific Cytokine Production by Peripheral Blood Mononuclear Cells Kiyoshi Yamazaki, Joseph A. Murray, Amindra S. Arora, Jeffery A. Alexander, Joseph H. Butterfield, Thomas C. Smyrk, Hirohito Kita Characterization of Oropharyngeal Swallow Motor Pattern in Patients with Neurogenic ysphagia Pere Clave, Rosa Terre, Alfonso Blanco, Marleen e Kraa, Meritxell Girvent, lisabet Palomera, Montserrat Bernabeu, Mateu Serra xpression of Cysteinyl Leukotrienes (CysLT) in sophageal Mucosal Biopsies of Children with Allergic osinophilic sophagitis (A) Sandeep K. Gupta, Marc Peters-Golden, Joseph F. Fitzgerald, Joseph M. Croffie, Marian. Pfefferkorn, Jean P. Molleston, Mark R. Corkins, Joel R. Lim Upright sophageal Multichannel Intraluminal Impedance and Manometry (MII-M) Is a Reliable iagnostic Tool When Using Viscous Test Solution Amine Hila, Janice Freeman, Shirley Jamison, Amit Agrawal, Lileetb Kong, onald O. Castell Bolus Transit Is More Important Than Pressure in valuating Patients with ysphagia Radu Tutuian, onald O. Castell enotes W Poster of istinction P-215

22 T U S A Y MAY 18 T1209 T1210 T1211 T1212 T1213 T1214 T1215 T1216 T1217 T1218 T1219 T1220 T1221 T1222 The Small Caliber sophagus: Clinical Features and Radiological iagnosis Anand P. Tamhankar, James. Huprich, Cedric G. Bremner, Giuseppe Portale, A1 Tafazzoli, Parakrama T. Cbandrasoma, Jeffrey H. Peters, Jeffrey A. Hagen, Steven R. emeester, Tom R. emeester A Prospective Analysis of Tricyclic Antidepressants and Anticholinergics in the Management of Functional and Motility isorders of the sophagus Charles W. Randall, Carlo M. Taboada, avid L. Stump, Cindy Rizo mpiric sophageal ilation in ysphagia Jeffrey S. Olson, Amnon Sonnenberg Prevalence of GR and Allergy in osinophilic sophagitis Andrew Coen, Kathryn Peterson, Holly Clark, van Moore, Kristen Hilden, John Fang Ambulatory sophageal Manometry for the valuation of Non-Cardiac-Chest-Pain (NCCP)- New Perspectives for a Forgotten Method Yuval Binder, hud Melzer Measurement of uration of Lower sophageal Sphincter (LS) Relaxation uring sophageal Manometry oes Not Contribute iagnostic Information Amit Agrawal, Amine Hila, Janice Freeman, onald O. Castell Proposed Revised Classification of sophageal Motility Abnormalities is Supported by Clinical Presentation Radu Tutuian, Amit Agrawal, Janice Freeman, onald O. Castell Long-Term ffect of Botulinum Toxin (BT) Injection in Patients with Achalasia - A Prospective Sing/e-Centre Cohort Study Jan Martinek, Marek Benes, Tomas Hucl, Pavel rastich, Pavel Taimr, Julius Spicak MII-pH for the etection of Acid and Non-acid Reflux in Patients with Persistent Globus-A Preliminary Study Sharmila Anandasabapathy, Barry W. Jaffin Intermittent ysphagia for Solids Associated with a Multi-Ringed Oesophagus: Clinical Features & Response to ilatation Greta S. C. Lee, avid de Carle, Philip I. Craig, John S. Freiman, Ian J. Cook Ineffective Contractions and Abnormal Bolus Transit Are Associated with Abnormal sophageal Smooth Muscle ynamics Radu Tutuian, Brandon S. Hunter, Brenda Hoffman, onald O. Castell Quality of Life (QOL) After Pneumatic ilation (P), Heller Myotomy (HM), or sophagectomy () for Achalasia Marcelo F. Vela, Farah Khandwala, onald Wachsberger, Joel. Richter Incidence of osinophilic sophagitis is Increasing in a Pediatric Population Richard J. Nod, Philip. Putnam, Margaret H. Collins, Amal H. Assa'ad, Scan C. Jameson, Rachel M Akers, Marc. Rothenberg sophagitis Is Very Common in Patients with Achalasia After Treatment with Pneumatic ilatation Yvonne Leeuwenburgh, Herman van ekken, Pieter Scholten, Jelle Haringsma, P.. Siersema, rnst J. Kuipers POSTR SSSIONS--CLINICAL SCINC T1223 T1224 T1225 T1226 Identification of Hiatal Hernia by Manometry: Is it reliable? Amit Agrawal, Amine Hila, Radu Tutuian, Janice Freeman, onald O. Castell Adaptation of the ating Pattern in Achalasia and Its Impact on Conventional Symptom Scoring Sofie Sengier, anny e Looze, Georges Van Made, Martine e Vos Reproducibility of Bolus Transit and Manometric Findings. Studies Using Combined Muhichannel Intraluminal Impedance and Manometry Radu Tutuiam onald O. Castell How Quickly o Patients with Acute sophageal Food lmpaction Seek Medical Attention? S. evi Rampertab, avid Lee, Kostas Sideridis, Simmy Bank, Nakechand Pooran AM-5:O0 PM Hall F ~ Sponsored by: Gastrointestinal Oncology COLON CANCR: CLINICAL III Immunohistochemical Prognostic Indicators of T1227 Gastrointestinal Carcinoid Tumors Masaki Kawahara, Makoto Kmmori, Michio Kaminishi, Kaiyo Takubo More Metachronous Adenomatous Polyps eveloped in T1228 the COX-2 Strongly xpressed Colon Cancers Than COX-2 Negative Ones Bong Hwa Lee, Hyun Joo Shin, Seung Wan Chae, Jin Hee Sohn xpression of a Novel Biomarker in Colonic Mucosa of T1229 Patients with Ulcerative Colitis at High Risk for Colon Cancer Xin Geng, Jim J. C. Lin, Kiron M. as Clinical and Pathologic valuation of Gastrointestinal T1230 Stromal Tumor (GIST) un Tack Park, Min Ki Kim, Sang Young Seol, Sang Hyuk Lee, Sam Yong Ji, Jung Myung Chung, Hye Kyoung Yoon PMS2, a Potential arly Biomarker of Colon Cancer T1231 Risk Hana Holubec, Lois Ramsey, Megan Wilson, Carol Bernstein, Katerina vorakova, Claire Payne, Harinder Garewal, Harris Bernstein ietary Modulation of Proliferation in the Colon: A T1232 Randomized Cross Over Trial of Wheat Bran, Wheat Bran Plus Resistant Starch, and Control iets in Volunteers on a High Red Meat iet Finlay A. Macrae, Jane Muir, Zhiye Si, Ken Sharp< P. S. Bhathal, Roberd Bostick Increased Leiden Mutation and ecreased Serum Levels T1233 of Vitamin A and Zeaxantin in Patients with Oesophageal, Gastric, Liver, Pancreatic and Colorectal Cancers Rumi Gyorgy, omotor Andras, Maria Figler Jr., Gasztonyi Beata, Par Alajos, Par Gabriella, Mozsik Gyula ffect of 5-Aminosalicylate (5-ASA) on the Recurrence T1234 Rate of Sporadic Colorectal Adenomas Wolff Schmiegel, Christian P. Pox, Markus Reiser, German 5-ASA Polyp Prevention Study Group (GAPPS) P-216 ~ enotes W Poster of istinction

23 POSTR SSSIONSmCLINICAL SCINC y T1235 T1236 T1237 T1238 T1239 Response to Celecoxib in Familial Adenomatous Polyposis (FAP) oes Not epend on Genotype or Adenoma Burden lizabeth Half, Li-Kuo Su, Simon Lunagomez, Gideon Steinbach, Sherri Patterson, Robin K. S. Phillips, Andrew Latchford, rnest Hawk, Patrick M. Lynch Is p21 xpression a Predictive Factor for Colon Adenoma Recurrence at One Year? Robert Benamouzig, Jacques eyra, Antoine Martin, Bernard Girard, Alain Attar, Baktiar Bejou, Stanislas Chaussade Potential Use of PC-NSAIs for Chemoprevention of Colon Cancer lizabeth ial, Rand oyen, Lenard Lichtenberger Scenarios for Colorectal Cancer Screening: Timely, Sensitive and Feasible. A New Perspective, educed from Autopsy ata Kaspar Geul, ik Habbema, Ching Ting, Paul Wilson, Fred Bosman, rnst J. Kuipers Statins o Not Reduce Colon Cancer Risk in Humans: A Case Control Study Vikas Khurana, Tejinder Singh, Rambabu Chalasani, Hanmanth Bejjanki, aniel L. Halberg, Charlton Fort AM-5:00 PM Sponsored by: Gastrointestinal Oncology GASTRIC CANCR: CLINICAL I T1240 T1241 T1242 T1243 T1244 T1245 Hall F Adenoma Carcinoma Sequence in the Stomach: Role of Cyclo-Oxygenase 2 Alba Rocco, Stefania Staibano, ebora Compare, Giovanni Autiero, G. e Rosa, Gabriele Budillon, Gerardo Nardone Allele 2 of the Interleukin-1 Receptor Antagonist Gene: An Independent Genetic Risk Factor in arly Gastric Cancer Juergen Glas, Helga-Paula Toeroek, Agnes Schneider, Guenter Bruennler, Reinhard Kopp, kkehard. Albert, Manfred Stolte, Christian Folwaczny, Christian Folwaczny Lack of Association of IL-1B Family, TNFA and" TGFB1 Gene Polymorphisms with Noncardia Gastric Cancer in a Population with High Helicobacter Pylori Infection Rate Maria Asuncion Garcia-Gonzalez, Mark Strunk, Rafael Benito, Santos Santolana, lena Piazuelo, Pilar Jimenez, Cristina Pascual, Pilar Felez, Miguel Angel Simon, nrique Quintero, Angel Lanas Prevalence of Interleukin 1 Genetic Polymorphisms in Subjects with and Without Positive Family History of Gastric Cancer Rocco Zagari, Luigi Ricciardiello, Michele Baglioni, Cristian Bonvicini, Veronica Lunedei, Cristina Martuzzi, Lorenzo Fuccio, nrico Roda, Franco Bazzoli In-silico ata-mining in Gastric Cancer - Are We Finding iamonds or Coal? Jan Leyden, Alan Moss, Peter oran, Padraic MacMathuna Polymorphisms in Inflammation-Related Genes Are Associated with Increased Risk of Gastric Carcinoma and arly evelopment of the isease Paulo Canedo, Lydie Gioia-Patricola, Ceu Figueiredo, Antonio C. Ferreira, Goncalo Regalo, Fatima Carneiro, Federico Canzian, Jose C. Machado T1246 T1247 T1248 T1249 T1250 T1251 T1252 T1253 T1254 T1255 T1256 T1257 T1258 Molecular and tmmunohistochemical valuation of the xpression of Telomerase in Gastric Carcinomas: Correlation with H. Pylori Infection Andreas Karameris, Panagiotis Sec'bopoulos, Theodore Rokkas Metbylenetetrahydrofolate Reductase Polymorphisnls and the Risk of Gastric Cancer Matthias berl ToBias Goethe, ]Lt/l./ icrke>.,\~ld~ca> Leodolter, Chrtstoph Roecken, Clau~ Luley, Peter Malfertheiner oes the Number of Genetic Polymorphisms Influence the Susceptibility to Gastric Cancer? Aldona lugosz, Grazyna Adler, Halina Jaroszewicz- Heigelmann, Andrzej Ciechanowicz The C(-1562)T Polymorphism of Matrix Metalloproteinase (MMP-9) Gene in Caucasians with Gastric Cancer Aldona lugosz, Grazyna Adler, Halina Jaroszewicz- Heigelmann, Andrzej Ciechanowicz Association of 1I--1 Polymorphism with IL-I~ Production in Gastric Cancer Kennosuke Shirai, Naoki Ohmiya, Kenji Kamiya, Tetsuo Matsuura, Ayumu Taguchi, Masayasu Ozeki, Nobuyuki Mabuchi, Akihiro Itoh, Yoshiki Hirooka, Yasumasa Niwa, Hidemi Goto P53 Mutations In Gastric Cancer In Japan Associated With Interleukin-lb Polymorphism Naoki Ohmiya, Ayumu Taguchi, Kennosuke Shirai, Nobuyuki Mabuchi, Akihiro Itoh, Yoshiki Hirooka, Yasumasa Niwa, Hidemi Goto Influence of Interleukin-8 Polymorphism on the Risk for Chronic Atrophic Gastritis and Gastric Carcinoma Ayumu Taguchi, Naoki Ohmiya, Kenji Kamiya, Tetsuo Matsuura, Kennosuke Shirai, Masayasu Ozeki, Nobuyuki Mabuchi, Hironobu Kanazawa, Akihiro Itoh, Yoshiki Hirooka, Yasumasa Niwa, Hidemi Goto I-I. Pylori Virulence Factors and Interleukin-lB Polymorphisms in Patients with High Risk Gastritis and First egree Relatives of Gastric Cancer Patients Andreas Leodoher, Thomas Wex, Kathlen Wolle, Matthias bert, Thilo Kaehne, Ulrich Peitz, Peter Malfertheiner Histological and Serum Risk Markers for arly Gastric Cancer Akiko Shiotani, Hiroyasu lishi, Noriya Uedo, Koji Higashino, Mitutaka Kumamoto, Yukinori Nakae, Shingo Ishiguro, Masaharu Tatsuta Subcellular istribution Alteration of IQGAP1, A- Catenin and B-Catenin May Be an arly and Reversible Marker for Gastric Premalignant Lesion Xun Cai, Calin Stoicov, Hanchen Li, Jean Marie Houghton Livin, a Novel Member of Inhibitor of Apoptosis, Is Marker of Poor Prognosis in Gastric Cancer ShuiPing Tu, Annie O. O. Chan, Marrie C. M. Lin, Xiaohua Jiang, S. K Lam, H. F. Kung, Benjamin C. Y. Wong The Study on Biomarkers for Predicting the evelopment of Gastric Cancer in a Population with High-Risk of Gastric Cancer in China Ji-You Li Nodular Gastritis Is a Risk Factor for iffuse-type Gastric Carcinoma in Japanese Young Patients Tomoari Kamada, Masaki Miyamoto, Masanori Ito, Kuniaki Sugiu, Hiroaki Kusunoki, Jiro Hata, Yuichi Nagashima, Soichiro Kido, Hiroshige Hamada, Ken Haruma enotes W Poster of istinction P-217

24 POSTR SSSIONS--CLINICAL SCINC T1259 A Tri-modal Approach to Patients with Locally Advanced Gastric Carcinoma: 5-Year Follow-up of a Phase I1 Trial nders K. Ng, Simon Wong, Wing Y. Chan, Winnie Chu, Sydney Chung AM-5:00 PM Hall F.,~(~.~ Mortal Convention Center AM-5:00 PM Hall F ~]~ Sponsored by: Growth, evelopment and Aging PIATRIC IB ifferent Patterns of Inflammatory Bowel isease T1260 Between African-American Children and Other Racial/ thnic Groups in a Large, Multi-Center Registry of 1640 Children Jolanda M. White, Siobhan O'Connor, Harland S. Winter, Melvin B. Heyman, Barbara S. Kirschner, George. Ferry, Robert Baldassano, Patricia Fain, Traci Clemons, Terry Smith, Benjamin. Gold Medication Adherence in Pediatric Crohn's isease T1261 Maria Oliva-Hemker, Vivian Abadom, Carmen Cuffari, Sarah Barry, Richard Thompson Prevalence of Low and Significantly Low Bone Mineral T1262 ensity Is Similar in Pediatric Ulcerative Colitis and Crohn's isease Helen Pappa, Catherine Gordon, Athos Bousvaros, Suzanne Muggeo, Tracee Cook, Richard Grand pidemiological Features of xtraintestinal TI263 Manifestations in Pediatric Patients with Inflammatory Bowel isease Melvin B. Heyman, George. Ferry, Barbara S. Kirschner, Traci Clemons, Benjamin. Gold, Robert N. Baldassano, Harland S. Winter, Stanley A. Cohen, Robert A. Cannon, Pat L. Fain, Terry Smith, Pediatric IB Consortium Siblings of Children with Inflammatory Bowel isease T1264 Muhammad A. Qureshi, ebra J. Lobato, Wen@ Plante, Jessica Guite, Linda B. Shalon Indeterminate Colitis in Children: A Significant T1265 Subgroup of Pediatric IB Ryan S. Carvalho, Vivian Abadom, Maria M. Oliva-Hemker, Carmen Cuftari The Use of 5-ASA for the Initial Treatment of Children T1266 with Crohn's isease Harland S. Winter, George. Ferry, Traci. Clemons, Benjamin. Gold, Robert N. Baldassano, Barbara S. Kirschner, Stanley A. Cohen, Melvin B. Heyman, Pat L. Fain, Vesna Vrhovac, Terry Smith, Pediatric IB Consortium Safety of High ose Oral Mesalamine in Pediatric T1267 Patients with Inflammatory Bowel isease Jaya Punati, Nader N. Youssef, Joel R. Rosh Outcome of Infliximab Therapy in Pediatric Crohn's T1268 isease : The First Three Years xperience Ana Maria G.A. Sant'Anna, France Gervais, Colette eslandres, rnest G. Seidman Sponsored by: Imaging and Advanced Technology WIRLSS CAPSUL IMAGING, HPATIC IMAGING The M2A Patency Capsule: The Berlin xperience T1269 Mariam L. Boivin, Winffied Voderhoher, Herbert Lochs Videocapsule ndoscopy Versus Barium Contrast T1270 Studies for iagnosis of Crohn's isease Alan L. Buchman, Frank Miller, Anita Wallin, Aqeel Chowdhry, Chul Ahn Sensitivity and Specificity of the "Red Blood T1271 Identification System (RBIs)" in Video Capsule nteroscopy (VC) Clementina Stgnorelli, manuele Rondonotti, Carla Abbiati, Gizela Beccari, Maurizio Vecchi, Massimo Primignani, Roberto de Franchis Therapeutic Impact of Capsule ndoscopy in the Work T1272 Up of Obscure Gastrointestinal Bleeding Tobias hmann, Hayssam Moubayed, Francois-Xavier Troillet, Maria-Anna Ormer, Pierre Michetti, Gian orta Capsule Videoendoscopy: oes It Change Patient T1273 Outcome? Results in 58 Consecutive Patients in a Tertiary Medical Center Olga Barkay, Sigal Fishman, Zamir Halpern Video-capsule ndoscopy (VC) in the Management of T1274 Acute Gastro-intestinal Graft Versus Host isease (GI- GVH) Vincent Maunoury, Ibrahim Yakoub-Agha, Pierre esreumaux, Francis Bauters, Jean-Pierre Jouet, Jean- Frederic Colombel Capsule ndoscopy Identifies Occult Small Bowel T1275 Crohn's isease rnest G. Seidman, Ana Maria G.A. Sant'Anna, Martha H. irks, Marie-Claude Miron The Value of Capsule ndoscopy for valuation of T1276 Abdominal Pain and/or iarrhea lizabeth J. Carey, Jonathan A. Leighton, Arthur. Shift, Russell I. Heigh, Virender K. Sharma, avid. Fleischer Comparison of MRI and Capsule-ndoscopy for the T1277 etection of Small Intestinal Polyposis in Patients with Familial Adenomatous Polyposis and Peutz-Jeghers- Syndrome Reiner Caspari, Marcus yon Falkenhausen, Joerg Heller, Carsten Krautmacher, Hans H. Schild, Tilman Sauerbruch Capsule ndoscopy Without Prior Small Bowel T1278 Radiology S. ar, S. H. Hussaini, H. R. alton Capsule ndoscopy - Role of Bowel Preparation in T1279 Successful Visualization Yaron Niv, Galia Abuksis Wireless Capsule ndoscopy For Obscure T1280 Gastrointestinal Bleeding: Single Center, One Year xperience Shou-Jiang Tang, imitrios Christodoulou, Simon Zanati, lena ubcenco, Gregory Monkewich, Naveen Arya, Maria Cirocco, Gabor Kandel, Paul Kortan, Gregory B. Haber, Norman. Marcon P-218 enotes W Poster of istinction

25 v T1281 T1282 T1283 T1284 T1285 T1286 Capsule ndoscopy in the valuation of Obscure Gastrointestinal Bleeding Yunhong Li, Zhaomin Xu, Longdian Chen, Chenggong Yu, Shutang Han, Zhihong Zhang Reaching the Ileo-Cecal Valve uring Capsule nteroscopy (C) Is Indipendent Both from Intestinal Preparation with Laxatives and from the Use of Prokinetic rugs prior to the xam manuele Rondonotti, Carla Abbiati, Clementina Signorelli, Gizela Beccari, Maurizio Vecchi, Massimo Primignani, Roberto de Franchis Usefulness of Contrast-nhanced Ultrasonography with Coded Harmonic Anglo Imaging to valuate Therapeutic ffects for Hepatocellular Carcinoma Naoki Hotta, Yoshitaka Fukuzawa, Ken Sato, Tadashi Macho, Minoru Ayata, Akihiko Okumura, Tetsuya Ishikawa, Shinichi Kakumu ~rhe "COCOCO" Study: Comparison of Second Generation Contrast Media nhanced Ultrasound to Computed Tomography in Liver Lesions Proven by Histology Oliver P. Benetka, Gerhard Meier, Christoph yon Ritter Focal Nodular Hyperplasia Can Be ifferentiated from Hepatocellular Adenoma in the Portal Venous Phase by Contrast-nhanced Ultrasonography Christoph F. ietrich, Andre Ignee, agmar Schreiber, Joerg Trojan, ominik Faust, Gudrun Schuessler Automated Color Segmentation Simplifies Quantification of Liver Fibrosis Marc Friedenberg, Chart Y. Chung, Larry S. Miller, Frederick Fleszler, Felice Banson, Rebecca M. Thomas, Frank Friedenberg AM-5:00 PM Hall F ~ Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB CONTROLL CLINICAL TRIALS IN HUMANS T1287 T1288 T1289 T1290 Safety, Tolerability and Immunogenicity of Natalizumab in a Phase III Study of Active Crohn's isease Therapy (NACT-I) Robert nns, Jean-Frederic Columbel, Brian Feagan, Stephen B. Hanauer, fan Lawrance, Rerno Panaccione, William J. Sandborn, Martin Sanders, Stefan Schreiber, Stephan R. Targan, Sander J. van eventer, Paul Rutgeerts A Multicentre Randomized Controlled Study of Safety and fficacy of Adsorptive Granulocyte and Monocyte Apheresis in Patients with Active Ulcerative Colitis Koji Sawada, Nobuo Hiwatashi, Akihiro Munakata, Hitoshi Asakura, Yasuo Suzuki, Tetsuichiro Muto, Bun-el Iizuka, Abby Saniabadi, Takashi Shimoyama Oral Lecithin with Retarded Release into the Colon Improves Chronic Active Ulcerative Colitis: A Phase IIA Study Wolfgang Stremmel, Alexandra Zahn, Frank Autschbach, Ulf Hinz, Robert hehalt, Uta Merle Randomised, ouble-blind, Placebo-Controlled Trial of Oral Aloe Vera Gel for Mild-Moderately Active Ulcerative Colitis Louise Langmead, Roger Feakins, Sue Goldthorpe, ftychia Tsironi, Anupama de Silva, erek Jewell, avid Rampton POSTR SSSIONS--CLINICAL SCINC T1291 T1292 Tl293 T1294 T1295 T1296 T1297 T1298 T1299 T1300 T1301 T1302 Sargramostim Therapy Induces Response Independent of C-Reactive Protein Levels in Patients with Moderately-to-Severely Active Crohn's isease {C) Joshua Korrenik, Brian ieckgraefe, John F. \'al~'ntmc Safety and Tolerability of Natalizumab in Patients Concurrently Receiving Infliximab in a Phase 2 Study of Active Crohn's isease Bruce. Sands, Richard A. Konarek, Jack Spainhour, Charles Barish, Scott Becker, Lawrence S. Goldhclg. Seymour Katz, Stephen B. Hanauer Thiopurine Methyl Transferase Activity Predicts Both Toxicity and Clinical Response to Azathioprine in Inflammatory Bowel isease: The London IB Forum Prospective Study Azhar R. Ansari, Su Yang Soon, James Lindsay, Monica Arenas, eborah Morris, Simon Greenfield, Lynette Fairbanks, hrutika Patel, Cathryn Lewis, John uley, Tony Marinaki, Jeremy Sanderson A Multi-center ouble-blind Randomized Placebocontrolled Study of an Oral Spherical Adsorptive Carbon (AST-120) for Anal Fistulas in Crohn's isease Yoshihiro Fukuda, Masakazu Takazoe, Akira Sugita, Takashi Shimoyama Supplemental N-Acetyl-L-Cysteine Improves the fficacy of Mesalazine in the Treatment of Mild to Moderate Ulcerative Colitis. Randomized, Placebo-Controlled, Pilot Study Luis Guijarro, Jose Mate, Venancio Gonzalez-Lara, Jose Lazaro Perez-Calle, lgnacio Marin, ncarna Arriaza, Tomas Olleros, Mario elgado, avid Prieto-Merino, Maria Sol Castillejo, Carlos Cara Immune Response to Influenza Vaccine in Pediatric Patients with Inflammatory Bowel isease Petar Mamula, Jonathan. Markowitz, Alexander Klimov, Louis J. Cohen, avid A. Piccoli, Robert N. Baldassano Infliximab in the Treatment of Moderate to Severe Glueocorticoid ependent Ulcerative Colitis: A Randomized Methylprednisolone Controlled Trial Alessandro Armuzzi, Andrea Lupascu, Paolo Fedeli, Barbara e Pascalis, Giovanni Gasbarrini, Antonio Gasbarrini fficacy of Mononuclear Cell Apheresis for Ulcerative Colitis: Comparison with Removal Filter Leukocytaphereses Mitsuki Miyata, Kunio Kasugai, Tetsuya Ishikawa, Akihiko Okumura, Shiniti Kakumu Semapimod Treatment of Crohn's isease Alan L. Buchman, Seymour Katz, Charles Barish, Richard lkin, Joshua Korzenik, Terry Plasse Long-term Follow-up Study of Chronic Ulcerative Colitis with Antibiotic Combination Therapy Toshifumi Ohkusa, Hiroto Miwa, Tetsuya Nomura, Takeshi Terai, Osamu Kobayashi, Mariko Hojo, Yoshiyuki Takei, Tatsuo Ogihara, Shu Hirai, Isao Okayasu, Nobuhiro Sato Bifidobacterium Longum BB-536 and Prevention of Acute Pouchitis Steven J. Brown, Jenkins Megan, Stuart Smith, avid Matchet, Ross lliott Fontolizumab (HuZAF TM) Pharmacokinetics (PK), Pharmacodynamics (P), Immunogenicity and xposure/ Response Relationship in Patients (Pts) with Moderate and Severe Crohn's isease (C) Han ing, Mauricio Maia, Steve Keller, Jean-Frederic Colombel, Sander van eventer, Jean-Paul Gendre, Walter Reinisch, Paul Rutgeerts, Meina T. Tang enotes W Poster of istinction P-219

26 T U S A Y MAY 18 T1303 T1304 T1305 T1306 T1307 T1308 T1309 T1310 T1311 T1312 T1313 T1314 Budesonide Foam vs. Budesonide nema in Active Ulcerative Proctosigmoiditis Volker Gross, Simon Bar-Meir, A La W, O Mickisch, Zsolt Tulassay, L Pronai, L. Kupcinskas, J Pokromieks, B Margus Long-term Follow-up arid Predictive Factors for Clinical Relapse in Patients with Collagenous Colitis After Induction of Remission with Budesonide Capsules Stephan Miehlke, Ahmed Madisch, Claudia Voss, berhard Kuhlisch, Andrea Morgner, Peter Heymer, Bernd Wigginghaus, Manfred Stoke Long-Term Safety of Budesonide Gary R. Lichtenstein, Bengt Bengtsson, Louise Hapten- White CP870, a Pegylated Humanized Anti-TNF Antibody Fragment, Improves Quality of Life in Patients with Moderate to Severe Crohn's isease Paul Rutgeerts, Richard Fedorak, Stefan Schreiber, Brian Feagan, Alison Innes, Peter Jeffery, Patrick Round Maintenance Treatment with Infliximab Reduces the Likelihood of Hospitalization in Patients with Fistulizing Crohn's isease Bruce. Sands, Songkai Yan, Mohan Bala, Marion A. Blank, Sander J. van eventer Randomized, ouble-blind, ouble-ummy, Controlled Trial of Subcutaneous Recombinant Human Interleukin- 11 Versus Prednisolone in Active Crohn's isease Klaus Herrlinger, Thomas Witthoeft, Andreas Raedler, Bernd Bokemeyer, Thomas Krummenerl, Joerg Schulzke, Norbert Boerner, Bruno Kueppers, Joerg mmrich, AxeI Mescheder, Ullrich Schwertschlag, Mark Shapiro, duard Stange Intermittent Therapy with Granulocyte and Monocyte Aphaeresis Maintains Remission in Ulcerative Colitis Atsushi Sakuraba, Toshiro Sato, Yuko Iwagami, Mikiko Izumiya, Yuichi Morohoshi, Shigeo Yoshizawa, Katsuyoshi Matsuoka, Osamu Hitotsumatsu, Tadakazu Hisamatsu, Susumu Okamoto, Hirinori Takaishi, Nagamu Inoue, Haruhiko Ogata, Yasushi lwao, Hiromasa Ishii, Norifumi Hibi Randomized Placebo Controlled Trial of Pro-and Prebioties (Synbiotics Cocktail) for Maintenance of Infliximab Induced Remission of Luminal Crohn's isease (C) Paul Rutgeerts, Geert 'Haens, Filip Baert, Gert Van Assche, Isolde Aerden, Maja Noman, Severine Vermeire, Stig Bengmark Mucosa-Associatecl Bacteria in Ulcerative Colitis Before and After Antibiotic Combination Therapy Tetsuya Nomura, Toshifumi Ohkusa, Tsutomu Yoshida, Isao Okayasu, Mitsuo Sakamoto, Hidenori Hayasbi, Yoshimi Benno, Shu Hirai, Osamu Kobayashi, Takeshi Terai, Hiroto Miwa, Yoshiyuki Takei, Tatsuo Ogihara, Nobuhiro Sato A Prospective Study of Selective Neutrophil and Monocyte Adsorptive Apheresis as a First Line Treatment for Steroid Naive Patients with Active Ulcerative Colitis: A Step Toward Steroid Free Treatment of Ulcerative Colitis Yasuo Suzuki, Naoki Yoshimura, Abby Saniabadi, Yasushi Saito The ffect of Infliximab Infusion on Semen Quality in Men with Inflammatory Bowel isease (IB) Urea Mahadevan, Paul J. Turek Budesonide Induces Remission Faster and More Often Than Prednisolone, in Moderately Active Ileo-Cecal Crohn's isease Reinhold W. Stockbrugger, Tore Persson, rik Schoon, Simona Bollani POSTR SSSIONS--CLINICAL SCINC AM-5:00 PM Hall F (~ Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB NATURAL HISTORY, COMPLICATIONS, AN OUTCOMS T1315 T1316 T1317 T1318 T1319 T1320 T1321 T1322 T1323 T1324 T1325 The Influence of Backwash Ileitis on the Late Outcome of the Ileoanal Pouch Anton J. Kroesen, Sonja ullat, Michael Fromm, Joerg. Schulzke, Heinz J. Buhr nvironmental Factors in Familial Crohn's isease in Belgium Herbert J. Van Kruiningen, Marie Joossens, Severine Vermeire, Sofie Joossens, Stephane ebeugny, Corinne Gower-Rousseau, Antoine Cortot, Jean-Frederic Colombel, Paul Rutgeerts, Robert Vlietinck A Population Based Case Control Study of Risk Factors for Crohns isease Charles N. Bernstein, Patricia Rawsthorne, James F. Blanchard oes "Clinical or Histological Activity of Ulcerative Colitis (UC) Predict an Increase in the Likelihood of the evelopment of Colorectal Carcinoma (CRC)/ysplasia? A Case Control Study Gwo-Tzer Ho, Roderick Gunn, Leif Torkvist, Alastair Lessells, Joseph Loane, Roger Malcolmson, Jack Satsangi The Life xpectancy of IB Patients in the UK Using Lifetable Methodology Timothy R. Card, Richard Hubbard, Richard F. A. Logan Serum Osteoprotegerin is Increased in Crohns isease: A Population-based Case Control Study Charles N. Bernstein, Michael Sargent, William. Leslie Microproteinuria in Patients with Inflammatory Bowel isease (IB): Is It Associated with the isease Activity or the Treatment with 5-Aminosalicylic Acid (5-ASA)? Androniki Poulou Jr., Konstantinos Goumas, imitrios andakis, Ioannis Tyrmpas, Maria Panagiotaki, George Papatheodoridis, Theodora Terzi, Cathrine Terzoglou, Androniki Georgouli, Ioannis Liosis, imitrios Soutos Strong Genetic Influence on Longitudinal Changes in Vienna Classification Characteristics - A anish- Swedish Cohort Study of IB Twins Tine Jess, Jonas Halfvarson, Lennart Bodin, Curt Tysk, Gunnar Jarnerot, Vibeke Binder Prospective Study on the Prevalence and Clinical Relevance of Cytomegalovirus (CMV) Infection in Ulcerative Colitis (UC) Roser Vega, ugeni omenech, Agueda Hernandez, Isabel Ojanguren, sther Garcia-Planella, Isabel Bernal, Merce Rosinach, Jaume Boix, duard Cabre, Miquel Gassull Should Perianal Crohns isease be Classified as Penetrating isease (B3) by the Vienna Classification? Ian. R. Arnott, Ben R. K. Smith, Hazel. rummond, laine R. Nimmo, Jack Satsangi Biological Sealant (Tissucol) in Treatment of Penetrating Modalities of Crohn isease Ignacio Fernandez-Blanco Hernaiz Sr., Ignacio Acitores, aniel Hervias, Francisco Javier Navajas, Francisco Ibanez, Gontrand Lopez-Nava P enotes W Poster of istinction

27 r POSTR SSSIONS~CLINICAL SCINC T1326 Antibiotic Use and the Risk of Flares of Inflammatory Bowel isease Faten Aberra, Colleen Brensinger, Warren Bilker, Brian Strom, Gary Lichtenstein, James Lewis T1340 pidemiology of Pediatric IB in the Greater Toronto Area T.. Walters, J. Critch,? Ktmclhal~ P Sherman A M Griffiths T1327 T1328 T1329 T1330 T1331 T1332 Prospective Study of 5-Amino Salicylate Nephrotoxicity in the UK Andrew F. Muller, Paul Stevens, Howard llison, Alistair Mclntyre, Richard Logan The vidence for Routine Measurements of Nutritional Parameters and Routine Multivitamin Supplementation in IB Regardless of isease Activity Kathy Vagianos, Savita Bector, Charles N. Bemstein Improvement of Bone Metabolism After infliximab Therapy in Crohn's isease Pal Miheller, Gyorgyl Muzes, Tamas Zagoni, Miklos Toth, Zsolt Tulassay Milder Inflammation of Colonic Mucosa Correlates with Lower Rates of Neoplastic Progression in Ulcerative Colitis Asher Kornbluth, Sierra Matula, Steven Itzkowitz, Noam Harpaz, Sari Feldman, Carol Bodian, Victoria Croog, Steven Weiner, Thomas Ullman Biopsy Specimen Numbers in the Routine Practice of Surveillance Colonoscopy in Ulcerative Colitis (UC) Thomas Ullman, Victoria Croog, Noam Harpaz, Steven Itzkowitz Altered Bone Mineral Metabolism in Children at Time of iagnosis of Inflammatory Bowel isease Manisha Harpavat, avid J. Keljo, A'elbert Bowen, Susan L. Greenspan T1341 T1342 T1343 T1344 T1345 T1346 The Clinical Course of Ulcerative Colitis After Orthotopic Liver Transplantation for Primary Sclcro,,mg Cholangitis Alexandra Seddon, Gwo-T=er Ho, George Thclupondo,. Peter Clive Hayes, Jack Satsangi Clinical Characteristics of Cytomegalovirus Infection in Surgically Resected Severe Refracto~ Ulcerative Colilis Akifumi Kuwabara, Haruhiko Okalnoto, [akc)a>u buda, Yoichi Ajioka, Katsuyoshi Hatakeyama Appendiceal Orifice Inflammation in Ulcerative Colitis: An Analysis in Relation to Clinical Course Jeong-Sik Byeon, Suk-Kyun Yang, Seung-Jae Myung, Seung I1 Pyo, Hyun Ju Park, Yun-Jung Lee, Gin Hyug Lee, Hwoon-Yong Jung, Weon-Seon Hong, Jin-Ho Kim, Young I1 Min xtraintestinal Manifestations of Crohn's isease: Which Are the Risk Factors? Manuel Barreiro-e Acosta, Aurelio Lorenzo-Gonzalez, Concepcion Nunez-Pardo, Amado Pena, nrique ominguez-munoz Pregnancy in Crohn's isease and Ulcerative Colitis Patients: Prospective Case-Control Italian Study Aurora Bortoli Can We Identify at iagnosis Patients with Mid-Term Benign Crohn's isease? Laurent Beaugerie, Jean Pierre Gendre, Jacques Cosnes T1333 Prognosis of Inflammatory Bowel isease-related and Sporadic Colorectal Cancer Thierry elaunoit, James F. Lymp, Paul J. Limburg, Richard M. Goldberg, Thomas C. Smyrk, dward V. Loftus Jr. T1347 Metabolic Bone isease in an Australian Crohn's Population N~tomi Lee, ian Templeton, Sue Mason, Graham Radford- Smith T1334 T1335 T1336 T1337 T1338 lnfliximab Therapy nhances Bone Formation in Active Crohn's isease Geert R. 'Haens, Maja Noman, irk Vanderschueren, Martin Hide, rik Vanherck, Paul Rutgeerts Bone Mass Is ecreased in Steroid Naive Children with Inflammatory Bowel isease Manisha Harpavat, Susan L. Greenspan, Silva Arslanian, avid J. Keljo Independent Risk Factors Predicting Recurrence and Time to Recurrence in an Australian Crohn's isease Population Graham Radford-Smith, Nirmala Pandeya, Georgia Hume, ian Templeton, Beth Fowler The Manitoba IB Cohort Project: The Interrelationship Between isease Activity, Psychosocial Factors, and Quality of Life Lesley A. Graft, John R. Walker, Kathy Couch, Linda Rogala, Patricia Rawsthorne, Laura Jakul, Jason P. diger, Cory McPhail, Charles N. Bernstein Increased Incidence of Azathioprine-induced Toxicity in Inflammatory Bowel iseases Compared to Other iseases Rinse K. Weersma, Frans T. Peters, Liekele. Oostenbrug, Aad P. van den Berg, Michiel van Haastert, Rutger J. Ploeg, M.. Posthumus, J. J. Homan van der Heide, Peter L. M. Jansen, Hendrik M. van ullemen T1348 T1349 T1350 T1351 T1352 ffect of Azathioprine/6-Mercaptopurine (AZA/6-MP) on Natural History of Inflammatory Bowel isease (IB) in a Population-Based Cohort Conor G. Loftus, dward V. Loftus Jr., William J. Tremaine, W. Scott Harmsen, Alan R. Zinsmeister, William J. Sandborn Metabolic Bone isease in Inflammatory Bowel isease - an pidemic? Gerald M. Fraser, Osnat Moreh, Bracha Hadad, Nehama Horev, Negba Segal, Negba Segal, Rivka Koren, Yaron Niv Analysis of Perinatal Complications and Their Predictive Value for the Risk of eveloping IB - Results of a Case Control Study Christian Maaser, Barbara Sonntag, Birgit Stolze, Andreas Lugering, mile J. M. Rijcken, Jan Heidemann, Christian F. Krieglstein, Wolfram omschke, Torsten Kucharzik Inflammatory Bowel isease: A Comparison of emographic and Clinical Characteristics Between White Patients and thnic Minorities Robin Forman, Georgia Panagopoulos, Nicole Gordon, Jeffrey Berger, Burton I. Korelitz Colectomy with lleorectal Anastomosis Preserves Female Fertility in Ulcerative Colitis Pierre. Mortier, Lnc Gambiez, Mehdi Karoui, Antoine Cortot, Jean C. Paris, Pierre Quandalle, Jean-Frederic Colombel T1339 Is Transmural Inflammation in the Ileoanal Pouch Significant? Maha Guindi, N. MacNeill, Robert H. Riddell T1353 Is the Risk of Fracture in Inflammatory Bowel iseases Related to Osteoporsosis? Timothy R. Card, Joe West, Richard Hubbard, Richard F. A. Logan enotes W Poster of istinction P-221

28 T U S A Y MAY 18 T1354 T1355 T1356 T1357 T1358 The volution of Fatigue in Patients with Crohn's isease After Treatment with Infliximab: A Prospective Study Philippe Persoons, Koen emyttenaere, Joris Vandenberghe, Lukas Van Oudenhove, Paul Rutgeerts High Adherence with Scheduled Infliximab Infusions for Crohn's isease Sunanda V. Kane, LaJuan Crivens Analysis of Concordance of isease Severity Features in a Central Pennsylvania IB Registry lan R. Schreibman, va Gatka, Jennifer L. Thompson, Lisa S. Poritz, Wen Jie Zhang, Susan Boehmer, Walter A. Kohun Pentasa (Mesalazine) Has a Low Incidence of Adverse vents in the Treatment of IB: A Review of Company ata up to August, 2002 Geert R. 'Haens, Marc Lemann, Axel ignass, Michael A. Kamm, Tina ruskeit, Karen Olsen, Musse Foldager Correlation of C-Reactive Protein (CRP) with Clinical, Radiographic, and ndoscopic Activity in Inflammatory Bowel isease (IB) Craig A. Solem, dward V. Loftus Jr., William J. Tremaine, W. Scott Harmsen, Alan R. Zinsmeister, William J. Sandborn AM-5:00 PM Hall F (~ Sponsored by: Motility & Nerve-Gut Interaction FUNCTIONAL GI ISORRS: PSYCHOSOCIAL Alterations in GI Symptoms, Psychological Status, and T1359 Brain Function Following Participation in Cognitive Therapy for IBS Jeffrey M. Lackner, Alan Lockwood, Mary Lou Coad, Thomas C. Mahl, Rebecca Firth, Howard Mertz, Leonard Katz, Susan Krasner, avid S. Wack, Paul Galantowicz ifferent Clinical Subgroups Have ifferent nergy T1360 Values of GS for Gastroparesis Nighat Abidi, Thomas k Abell, Amar A1-Juburi, Warren Starkebaum What Factors xplain Health Related Quality of Life T1361 (HRQOL) in Functional Bowel isorders (FB) ouglas A. rossman, Carolyn B. Morris, Yuming Hu, Carlar Blackman, Brenda B. Toner, Nicholas. iamant, William. Whitehead, Jane Leserman, Shrikant Bangdiwala The Relationship Between Illness Related Attitudes and T1362 Beliefs and Clinical Outcome in Functional Bowel isorders (FB) Albena Halpert, Carolyn B. Morris, Brenda B. Toner, Nicholas. iamant, William. Whitehead, Yuming Hu, Jane Leserman, Shrikant Bangdiwala, ouglas A. rossman Factors Predicting Illness Related Attitudes and Beliefs. T1363 Validation of the GI-IMIQ in Functional Bowel isorders (FB) Albena Halpert, Carolyn B. Morris, Brenda B. Toner, Nicholas. iamant, William. Whitehead, Yuming Hu, Jane Leserman, Shrikant Bangdiwala, ouglas A. rossman Constipated Subjects Reporting Physical Abuse Are T1364 More Likely to Fail an ducation/medical Management Intervention Steve Heymen, Yolanda Scarlett, William. Whitehead POSTR SSSIONSmCLINICAL SCINC T1365 T1366 T1367 T1368 T1369 T1370 T1371 T1372 T1373 T1374 T1375 T1376 T1377 T1378 T1379 T1380 Irritable Bowel Syndrome in a Norwegian Population: Prevalence and Association with Mood isorders and Musculoskeletal Complaints Per O. Vandvik, Per G. Farup Rome II Criteria in Pediatric Abdominal Pain: Parent, Child, and Clinician Agreement Craig A. Friesen, Jennifer V. Schurman, Caroline. anda, Linda Andre, leanor Welchert, Teri Lavenbarg, Jose T. Cocjin, Paul. Hyman Volume to Fullness in Patients with Chronic Nausea Reflects Quality of Life but not Psychiatric Comorbidity ric Lee, Michael P. Jones The Impact of Intensive Cognitive Behavioural and Medical Therapy on Symptom Intensity and Bothersomeness on Long-term Outcome of Functional yspepsia. A Prospective, Randomized Trial Sebastian Haag, Sefik Tagay, Matthias Langkafel, Gereon Heuft, Nicholas J. Talley, Wolfgang Senf, Gerald Holtmann Is Health Care Seeking for Irritable Bowel Syndrome (IBS) and Functional yspepsia (F) a Socially Learned Response to Illness? Natasha A. Koloski, Philip M. Boyce, Nicholas J. Talley Severity of Constipation and Anxiety Predict Failure to Improve with Conservative Medical Treatment for Constipation Steve Heymen, Yolanda Scarlett, William. Whitehead epression and Abdominal Pain in Irritable Bowel Syndrome: The mediating Role of Catastrophizing Jeffrey M. Lackner, Brian Quigley, dward B. Blanchard Are Patients with IBS More Likely to Seek a Physical Rather Than a Psychological xplanation for Unexplained Symptoms? Benjamin Bray, Ian Penman, Michael J. Ford Pain and Functional isability in Children with Functional Gastrointestinal isorders (FGs) Jennifer V. Schurman, Caroline. anda, Craig A. Friesen, leanor Welchert, Linda Andre, Teri H. Lavenbarg, Jose T. Cocjin, Paul Hyman ducation and Medical Management Resolve Fecal Incontinence in 35%, but epression and Greater Symptom Severity Predict a Poor Response Steve Heymen, Yolanda Scarlett, William. Whitehead IBS Patients' Response to Abdominal Pain: Too Sensitive, Too Tough, or Both? Jeffrey M. Lackner, Thomas C. Mahl, Gregory. Wilding Coping Strategies (CS) in FGI: Preliminary Observations Sarah Wessinger, Lorrie Maynard, Michael. Crowell, Michael P. Jones Acid Secretion in Flinders Sensitive Line Rats Chang-Cheng Wang, lreneusz T. Padol, Gervais Tougas, Richard H. Hunt Comparison of Health-Related Quality of Life in GR, Peptic Ulcer isease and Ulcerative Colitis wa I. Malecka - Panas, Katarzyna Jurek, Anna Mokrowiecka Psychosocial Profiling of Children with Chronic Abdominal Pain Caroline. anda, Jennifer V. Schurman, Teri H. Lavenbarg, Craig A. Friesen, leanor Welchert, Linda Andre, Jose T. Cocjin, Paul. Hyman Natural History of Post-Infectious GI-Symptoms Hans Tornblom, Pia Holmvall, Bo Svenungsson, Greger Lindberg P-222 enotes W Poster of istinction

29 POSTR SSSIONS~CLINICAL SCINC AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Motility & Nerve-Gut Interaction GASTRIC MOTILITY AN SNSATION xaggerated Gastric Accommodation in Patients with T1381 Obesity Xiaohua Hou, Xiaoping Xie, Yong Xu, Jiande Chen The Glutamate Analogue, N-Methyl--Aspartate T1382 (NMA), Non-Specifically Activates Inferior Splanchnic Afferent Fibers Innervating the istal Colon Yuhua Wang, James A. McRoberts, meran A. Mayer ffect of Gastric Administration of Capsaicin on Sensory T1383 and Motor Responses to Repeated istensions in Man Maura Corsetti, Rita Vos, Jozef Janssens, Jan Tack T1384 T1385 T1386 T1387 T1388 T1389 T1390 T1391 T1392 T1393 Potent Inhibitory ffects of Tachygastria on Antral Motility in ogs Hut Ouyang, Jieyun Yin, Jiande Z. Chen ffect of Retrograde Gastric lectrical Stimulation on Food Intake in the Healthy Humans Shukun Yao, MeiYun Ke, ZhiFeng Wang, abo Xu, Yanli Zhang, Xuanping Xia, Hui Xu, Zhang Xu, J.. Z. Chen Suppression of Myenteric nnos xpression by Advanced Glycation nd-products (AGs) and Their Receptor (RAG)- a Possible Mechanism for iabetic Gastroparesis Keiko Korenaga, Maria-Adelaide Micci, Pankaj Pasricha ffect of Mitemcinal Fumarate (GM-611) on Gastric mptying in Patients with Idiopathic or iabetic Gastroparesis John Fang, Richard McCallum, John ibase, Colleen Schmitt, Mark Kipnes Vagus Mediates Postprandial Coordination Between the Antrum and Pylorus in Conscious ogs Tomio Ueno, Kenichiro Uemura, Makoto Tatewaki, Mary B. Harris, Theodore N. Pappas, Toku Takahashi ffects of Clonidine and Sumatriptan on Liquid. Gastric mptying, Accommodation and Antral Motility as Assessed by MRI in Health Monika A. Kwiatek, Andreas Steingoetter, Geoff Hebbard, Wemer Schwizer, Michael Fried, Miriam Thumshirn The Use of Intra-Gastric lectrical Measurements for Automatic ating etection (A) Ricardo Aviv, Claudia P. Sanmiguel, Shai Policker, Ophir Bitton, Walid Hadad, Shlomo Ben Haim, dy. Softer ffects of uodenal lectrical Stimulation (S) on Gastric Tone and Gastric Accommodation in og Jieyun Yin, Hut Ouyang, Jinhong Xing, Jiande Chen The Gastric Ligament Muscle; a New Innervated Structure? Marcello Costa, Kate Brody, Charles Humphreys, Simon J. H. Brookes Relationship Between Increased uodenal Acid xposure and yspeptic Symptoms in Functional yspepsia Kwang-Jae Lee, Ingrid emedts, Philip Caenepeel, aniel Sifrim, Jozef Janssens, Jan Tack T1394 T1395 T1396 T1397 T1398 T1399 T1400 T1401 T1402 T1403 T1404 T1405 T1406 T1407 Temporary Gastric lectrical Stimulation Improves Symptoms of Nausea and Vomiting in Patients with Both elayed and Non-elayed Gastric mptying Oscar Batista, Robert Schmieg, Thomas k Abell Beyond the Myths -- Herbal xtracts ltave Potent and Region-Specific ffects on Gastric Motility Barbara Hohenester, Anne Ruhl, Michael Schcmann Previous Helicobactcr pylori (Hp) Infection and Functional yspepsia: a Role for Cellular Rather lhan Humoral Immune Activation in the Maintenance of Gastric Motor ysfunction Premysl Bercik, lena F. Vcrdu, Ya>uaki Motomula. \,aumt Cermak, Kenneth Croitoru, Stephen Collins Treatment of iabetic Gastroparesis by High-Frequency Gastric lectrical Stimulation Richard W. McCallum, Zhiyue Lin, Irene Sarosiek, Katherine Roeser, Jameson Forster Influence of Ghrelin on Gastric mptying and Meal- Related Symptoms in Gastroparesis Jan Tack, Inge epoortere, Raf Bisschops, Kristin Verbeke, Jozef Janssens, Theo Peeters ffect of Insulin-lnduced Hypoglycemia on Gastric mptying in Longstanding Type 1 iabetes Mellitus Antonietta Russo, Julie. Stevens, Richard Chen, Richard Burnet, Michael Horowitz, Karen L. Jones Calorie Intake Prolongs Gastric mptying of Solid rug osage Forms i a Magnetic Marker Monitoring (MMM) Study Kilian Fach, Olaf Kosch, Wemer Weitschies, Ivo van der Voort, Christiane Schiller, Lutz Trahms, Bertram Wiedenmann, Hubert Moennikes Simultaneous Gastric mptying and Accommodation Followed by Combined Satiety and GG Testing for htvestigating Pathophysiological Abnormalities in yspepsia Kishore V. Gaddipati, Steven Kantor, Hrair P. Simonian, Robert S. Fisher, Linda C. Knight, Alan H. Maurer, Henry P. Parkman Role of Nitric Oxide and Pyloric Tone in Intestinal lectric Stimulation-Induced elayed Gastric mptying in ogs Xiaotuan Zhao, Lijie Wang, ouglas L. Brining, J.. Z. Chen oes Chronic Gastric lectrical Stimulation (GS) for Gastroparesis Reduce the Use of Prokinetic/Antiemetic Medications? Zhiyue Lin, Irene Sarosiek, Jameson Forster, Richard W. McCallum Relationship of the Nutrient rink Test and Gastric Volumetric Measurements in Health and Community yspepsia Jonathan Gonenne,. Janet Castillo, uane Burton, George Thomforde, Karl Baxter, Alan Zinsmeister, Michael Camilleri Influence of Fearful Mood and motional Context on Gastric Sensorimotor Function in Man Joris Vandenberghe, Lukas Van Oudenhove, Brecht Geeraerts, Lloyd Gregory, Qasim Aziz, Philippe Persoons, Jozef Janssens, Jan Tack Gastric lectrical Stimulation Synchronized with Gastric Slow Waves nhances Gastric Contractions Zhishun Wang, Lijie Wang, ouglas Brining, Jiande Chen Cardiac Vagal ffects of Gastric lectrical Stimulation in Patients with Gastroparesis Thomas V. Nowak, Joel Hammond, Lyn Ring, Adam Nowak, Barry Williams, John Kalbfleisch enotes W Poster of istinction P-223

30 T U S A Y MAY 18 T1408 T1409 T1410 T1411 T1412 T1413 T1414 T1415 T1416 T1417 T1418 T1419 T1420 T1421 T1422 P-224 Inhibitory ffects of uodenal Fat on Gastric Slow Waves and mptying Are Mediated via Cholecystokinin Hongbing Zhu, Xiaobong Xu, Jiande Chen Altered Gastric Accommodation and mptying Can Be Revealed in yspeptic Patients with Magnetic Resonance Imaging Ivo R. van der Voort, Hassan Abou-Rebyeh, Kilian Fach, Marco Schmidtmann, Viola Andresen, Christoph Werner, Burghard F. Klapp, Bertram Wiedenmann, Hubert Moennikes Two-channel Gastric lectrical Stimulation Accelerates elayed Gastric mptying Induced by Vasopressin Gengqing Song, Bin Yang, Xiaohua Hou, Wei Qian, J.. Z. Chen Burn-Induced Gastric mptying elay in Rats and the ffect of Selective COX-2 Inhibitors Hermes Oliveira, Jonathan spana, ai Chung, Jiande Chen, avid Herndon Characterization of the Time Course of Gastric lleus Using Gene xpression Profiling Matthew A. Firpo, Robert. Glasgow, Sean J. Mulvibill elay in Gastric mptying in Patients with Chronic Renal Failure Hans Strid, Magnus Simren, Per-Ove Stotzer, Hasse Abrahamsson, inar Bjomsson Gastric mptying in the Critically Ill: Relationship Between Scintigraphic and Carbon Breath Test Measurements Marianne Chapman, Robert Fraser, ylan Bartholomeusz, Stephanie Creed, Antonietta Russo, Karen Jones, Max Bellon, Barry Chatterton, Michael Horowitz Validation of an Office-Based Gastric Motility Breath Test (GMBT) avid A. Wagner, aniel L. Bolt A Mouse Model of Sepsis Correlating Clinical Parameters with the Study of Mechanisms of Altered Gastric mptying Andrew J. W. Samis, Gerald P. Morris, William G. Paterson, Stephen J. Vanner ffects of Acute Intravenous Administration of Citalopram on Gastric Sensorimotor Function in Man Lukas Van Oudenbove, Cindy Casteels, Rita Vos, Jozef Janssens, Jan Tack Sildenafil Augments ecreased Nitric Oxide Signaling in nteric Tissues Judsen. Schneider, Hsiao-Huei Wu, Christopher. Ferris Neuroimmunity and Markers of Motility in the Myenteric Plexus in Patients with Achalasia Ines Gockel, Juergen R.. Bohl, Soroush oostkam, Volker F. ckardt, Theodor Junginger Gastric mptying and Intestinal Transit of Gastroretentive Tablets in the Fed State: ffect of Meal Content and Tablet Size Veme. Cowles, Gloria Gusler, Tung-Fen Chen, Sui Yuen. Hou, Ian Wilding, Bret Bemer Characterization of the Influence of Autonomic Neuropathy and the Metabolic Status on the Gastric mptying in Patients with Type-2 iabetes Tamas Varkonyi, Robert Takacs, Richard Roka, Mate Lazar, Laszlo Madacsy, Csaba Lengyel, Peter Kempler, Laszlo Pavics, Janos Lonovics Telemetric Recording of Gastric, Small Intestinal and Colonic Motility with Strain Gauge Transducers in Awake Rats Tobias Meile, Joerg Glatzle, Kerstin Spura, Tilman T. Zittel POSTR SSSIONS--CLINICAL SCINC T1423 T1424 T1425 T1426 T1427 T1428 T1429 T1430 A Pilot Study in the evelopment of a Breath Test for Gastric Accommodation Assessment in Man Cindy Casteels, Rita Vos, Raf Bisschops, Kristin Verbeke, Jozef Janssens, Jan Tack ffects of Vasopressin and Gastric lectrical Stimulation on Gastric mptying, Postprandial Gastric and Intestinal Slow Waves and Symptoms in ogs Xiaohong Xu, J.. Z. Chen Comparison of Nonadrenergic Noncholinergie Response in Isolated Gastric Smooth. Muscles from Wistar Kyoto and Sprague awley Rats Maria Astin, Terese Stromgren, Hillevi Mattsson Blockade of the Nitrergic Neural Pathway Abolishes the Inhibitory ffect of Gastric lectrical Stimulation on Canine Gastric Tone Jinhong Xing, Hongbing Zhu, Jiande Chen ffects of Sildenafil on Gastric Tone, Antral Contraction, mptying and Slow Waves in ogs Xiaohong Xu, Hongbing Zbu, Jiande Chen nergy-ependent ffects of Gastric lectric Stimulation on Proximal Gastric Tone Ying Sun, Jiande Chen Fasting Gastric Volume and Gastric mptying in Satiation and Symptoms in Functional yspepsia in a Tertiary Center Silvia elgado-aros, uane Burton, Irene Ferber, Michael Camilleri Adaptive and Maladaptive Coping Strategies for the Management of Vection-Induced Nausea and Motion Sickness Max. Levine, Robert M. Stem, Kenneth L. Koch ASG Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pro. AM-5:00 PM Hall F RCP BILIARY T1431 T1432 T1433 ndoscopic Therapy of 110 Patients with Primary Sclerosing Cholangitis in a Single Centre, Johannes Wittmann, George J. M. Webster, Adrian R. W. Hatfield, Stephen P. Pereira Long Term Plastic Stent Treatment for Benign Bile uct Strictures: Not Always a "Benign" Course oug Tran, Sean Lee, Rama Venu, Allan G. Halline, Russell. Brown Long-Term Results of Patients with Benign Biliary Strictures Treated with ndoprosthesis Yutaka Noda, Naotaka Fujita, Go Kobayashi, Katsumi Kimura, Kei Itoh, Jun Horaguchi, Osamu Takazawa, Atsuo Matsunaga, Mikiko Nomura, Kazuo Ishida, Toshiki Sugawara ASG Poster Session AM-5:00 PM Hall F RCP BILIARY T1434 Is There a ifferent Outcome Between ndoscopic Treatment of Intrahepatic (IHBL) Versus xtrahepatic Biliary Leak (HBL)? Susana scalante-glorsky, Hasbim Khandawalla, Claudio Navarrete, Marc Catalano, Isaac Raijman Sr.

31 POSTR SSSIONS--CLINICAL SCINC T1435 T1436 T1437 New Methods: Rendezvous Technique Is Used to Seal Biliary Leak After PTB (Percutaneous Trans-Hepatic Biliary rainage) with Transpapillary Injection of N- Butyl-2-Cyanoacrylate (Histoacryl) Nobuo Toda, Yukinaga Yukinaga, Hiroki Matsumoto, Hiroki Matsumoto, Makoto Taniguchi, Hayato Nakagawa, Takao Kawabe, Masao Omata, Kazumi Tagawa, Masao Omata Comparative Outcome of Iatrogenic Versus Traumatic Bile Leak After ndoscopic Therapy Susana scalante-glorsky, Hashim Khandwalla, Marc Catalano, Claudio Navarrete, Isaac Raijman St. Outcome of Biliary Leaks (BL) After ndoscopic Therapy in Immunocompromised Versus lmmunocompetent Patients Susana scalante-glorsky, Hashim Khandawalla, Claudio Navarrete, Marc Catalano, Isaac Raijman Sr. ASG Poster Session AM-5:00 PM RCP BILIARY T1438 T1439 T1440 T1441 T1442 T1443 T1444 T1445 T1446 Hall F Comparison of Radiation osimetry ffects of Metallic Biliary Stents Peter arwin, ric Goldberg, X. Allen Li iagnosis and Patients Management of Gallbladder isease by Bile Cytology Using ndoscopic Transpapillary Gallbladder rainage Tube Takao ltoi, Kazuto Nakamura, Atsushi Sofuni, Fumihide Itokawa, Kazuhiro Kakimi, Jun Sanada, Fuminori Moriyasu A Prospective Study of the arly Use of Needle-Knife for ifficult Biliary Cannulation Arthur J. Kaffes, Guduru Rao, Parupudi Sriram,. Santosh,. Nageshwar Reddy Pancreatic uct Stent Occlusion - Can It Be Predicted? Miriam Thomas, Marc F. Catalano, Joseph. Geenen Importance of Real Time Interpretation (INTRP) of RCP Films Over Conventional Static Images: Medicolegal Implications Miriam Thomas, Joseph. Geenen, Marc F. Catalano Stenting of the Pancreatic uct to Aid in Common Bile uct Cannulation uring ndoscopic Retrograde Cholangiopancreatography Mark Titus, ric Goldberg, Oleh Haluszka, Peter arwin Assessment of Occult Pancreatobiliary Reflux by Biliary Amylase Levels in Patients with Pancreaticobiliary isease Takao Itoi, Kazuto Nakamura, Atsushi Sofuni, Fumihide Itokawa, Kazuhiro Kakimi, Jun Sanada, Fuminori Moriyasu ndoscopic Stenting of the Gallbladder in Patients with nd Stage Liver isease and Symptomatic Gallbladder isease Jason. Conway, Mark W. Russo, Roshan Shrestha Yield of Repeat RCP for Persistently levated LFTs After a Previously Normal Cholangiogram in Liver Transplant Patients with Choledochocholedochostomy Anastomosis van L. Fogel, Lee McHenry Jr., James L. Watkins, Suzette Schmidt, A. J. Tector, Jonathan A. FridelI, Stuart Sherman, Glen A. Lehman T1447 T1448 T1449 T1450 T1451 T1452 T1453 T1454 T1455 T1456 T1457 T1458 Peroral Cholangioscopy in Combination with ndoscopic Transpapillary Bile uct Biopsy in thc iagnosis of xtrahepatic Bile uct Cancer Yasuhiro Nakano, Sato>hi Tanno, Man4bLt (')s4nm l\~'l-tt,,a Koizumi, Yusuke Mizukami, Toshikatsu Ol<umura. YutM,a Kohgo valuation of Mucosa in arly Gallbladder Carcinmna by Using ouble Contrast Cholangiography Koji Yoshida evelopment of a Biliary Stricture Model in Yucatan Miniature Swine Scott W. Grisolano, Bre~ T Peter>cn. gori J MOIIIIa, Judl, L. eters, Thomas C. Smyrk Predictors of ndoscopic Therapy Outcome in Orthotopic Liver Transplantation Patients xperiencing Biliary Leak or Stricture All Fazel, Henry Chiu, Shea Ross, Consuelo Soldevila-Pico, Koorosh MoezArdalan, Christopher Forsmark Selective Cannulation of the Common Bile uct: A Randomized Controlled Trial Comparing Sphincterotomes Neena S. Abraham, Stacey P. Williams, Kara Thompson, Jonathan Love, on Macintosh Common Channel Formation and Associated Pancreaticobiliary isease: Prospective Study by RCP Terumi Kamisawa, Masami Yoshiike, Naoto gawa, Hitoshi Nakajima, Atsutake Okamoto Giant Ampullary iverticula: Spectrum of isease and Success of Cannulation Marc F. Catalano, Suku George, Miriam Thomas, Meng Hua, Joseph. Geenen Occult Pancreatobiliary Reflux and Associated Mucosal Changes of the Gallbladder J{n Kan Sai, Masafumi Suyama, Yoshihiro Kubokawa, Hiroyuki Tadokoro, Nobuhiro Sato Post-RCP Radiology Interpretation of Cholangiopancreatograms Appears To Be of Limited Benefit and May Be Inaccurate Nitin Khanna, Gary May, Marty Cole, Syd Bass, Joe Romagnuolo Success of ndoscopic Therapy in Traumatic Bile uct Lesions Andreas Adler, Winfried Veltzke, Hassan Abou-Rebyeh, Bertram Wiedenmann, Peter Neuhaus, Rainer Hintze ilated ucts: Is It a Reliable Sign for Choledocholithiasis in Patients with Acute Calculous Cholecystitis (ACC)? Affan Quadri, Marc F. Catalano, Joseph Geenen eep Cannulation of the Common Bile uct at ndoscopic Retrograde Cholangiopancreatography: How Challenging Is It? Mohammad Wehbi, Kamil Obideen, Amaar Ghazale, Aasma Shaukat, Qiang Cai ASG Poster Session AM-5:00 PM Hall F RCP BILIARY T1459 Biliary Stent Clogging Solved by Nanotechnology? An in-vitro Study Uwe Seitz, Andreas Block, Tina Schaefer, Uwe Wienhold, Sabine Bohnacker, Klaus Siebert, Stefan Seewald, Frank Thonke, Boris Brand, Peter Schaefer, Nib Soehendra P-225

32 T U S A Y MAY 18 T1460 T1461 Surface Modification with Anti-adhesion Peptide: A Novel Approach to Prevent Bacterial Attachment and Biliary Stent Blockage Joseph W. Leung, Yan-Lei Liu III, Xiao-Bing Wang, Rajendra Ramsamooj, Kit S. Lain valuation of a Modified uodenoscope Facilitating Guidewire Fixation for RCP Michelle C. Beilstein, Nuzhat A. Ahmad, Michael L. Kochman, William B. Long, Janak N. Shah, Gregory G. Ginsberg ASG Poster Session AM-5:00 PM Hall F RCP BILIARY T1462 T1463 T1464 T1465 T1466 T1467 T1468 T1469 Covered Metallic Stents for the Management of istal Malignant Biliary Obstruction -Risk Factors for the Specific Complications Hiroyuki Isayama, Yousuke Nakai, Yutaka Komatsu, Takeshi Tsujino, Nobuo Toda, Naoki Sasahira, Natsuyo Yamamoto, Kenji Hirano, Minoru Tada, Haruhiko Yoshida, Takao Kawabe, Masao Omata A Randomized Controlled Comparative Study of Covered Versus Uncovered Self-xpandable Metal Stent for Malignant Biliary Obstruction S. H. Lee, Sang Woo Cha, Young Koog Cheon, Y. Kim, J. H. Moon, Y.. Cho, Y. S. Kim, J. S. Lee, M. S. Lee, Chan Sup Shim, Boo Sung Kim A Randomized Multicenter Trial Comparing Plastic to Covered Metal Stents for the Palliation of Lower Malignant Biliary Obstruction: A Planned Interim Analysis Peter L. Moses, Alan N. Barkun, Stuart R. Gordon, Roger. Mitty, M. Stanley Branch, Thomas. Kowalski ndoscopic 6mm Zilver Self-xpanding Metal Stents (SMS) for Malignant Obstruction of the Bifurcation: A Pilot Study Christopher Lawrence, avid J. esilets, onald. Conklin, Frank J. Lukens, Sunil G. Sheth, Willis G. Parsons III, ouglas A. Howell ndoscopic rainage of Malignant Common Bile uct (CB) Stenosis by a Covered Metal Stent (CMS) : Results of a Prospective Study imitri Coumaros, Bertrand Napoleon, A. Balamane, Marc Barthet, Rene Laugier, enis Sautereau, Thierry Yzet, Philippe esurmont, Jean Marc Canard, Thierry Ponchon, Societe Francaise d'ndoscopie igestive (SF) The ffectiveness of Ciprofloxacin in Prolonging Plastic Biliary Stent Patency: A Randomized Controlled Trial Gabriel Chan, Jeffrey Barkun, Neena Abraham, Alan Barkun, ric Valois, Albert Cohen, Gad Friedman, Jose Parent, Robert nns, Jonathan R. Love, Vicky Baffis, Mansour Jabbari, Peter Szego, Larry Stein Management of Biliary Obstruction in Patients Requiring uodenal Self-xpandable Metal Stent Placement mad Abu-Hamda, Bret T. Petersen, Todd H. Baron, Mark V. Larson, Michael J. Levy, Christopher J. Gostout Internal Biliary rainage is Superior to xternal Biliary rainage in Reversing Kupffer Cell ysfunction in Rats with Obstructive Jaundice Wen Li, Billy C. S. Leung, Angus C. W. Chan, Sydney S. C. Chung POSTR SSSIONSmCLINICAL SCINC T1470 T1471 T1472 T1473 T1474 T1475 Prospective Assessment of Patient Outcome Following Photodynamic Therapy for Advanced Cholangiocarcinoma Gavin Harewood, Todd Baron, Ashwin Rumalla, Kenneth Wang, Gregory Gores, Linda Stadheim, Piet de Groen Partially Covered Metal Stenting in Patients with Symptomatic Common Bile uct Stenosis Secondary to Chronic Pancreatitis: A Pilot Study Paolo Cantu, Alejandro Morales, Olivier Le Moine, Jacques eviere Additional p53 and K-ras Immunohistochemical Stain Can Not nhance the Outcome of Brush Cytology uring RCP Ho Gak Kim, Joong Goo Kweon, un Young Kim, Chang Hyeong Lee, Jong Seok Bae, Sun Woo Park Utility of Intraductal Ultrasonography for the Assessment of Cystic uct Patency to valuate the Risk of Acute Cholecystitis After Biliary Metallic Stent Placement Yousuke Nakai, Hiroyuki Isayama, Yutaka Komatsu, Takeshi Tsujino, Nobuo Toda, Naoki Sasahira, Natsuyo Yamamoto, Kenji Hirano, Minoru Tada, Takao Kawabe, Masao Omata Comparison of the Zilver Stent to Three Other Self- xpanding Metal Stents (SMS) in the ndoscopic Palliation of Malignant Biliary Obstruction Sinda Mein, lizabeth Cruz, Karen C. Bagatelos, James W. Ostroff Metal Versus Plastic Stents in Malignant Biliary Obstruction: A Meta-Analysis of the ffect on Long- Term Patency Arno ormann, Manuel Perez-Miranda, Nathalie Verin, Antoinette Wenk Lang ASG Poster Session AM-5:00 PM Hall F RCP BILIARY T1476 T1477 RCP with Sphincter of Oddi Manometry (SOM) at an Ambulatory ndoscopy Center (AC): An Assessment of Complications rik Springer, Yang K. Chen, aus Mahnke, Mainor R. Antillon, Raj J. Shah High Prevalence of Sphincter of Oddi ysfunction in Patients with Biliary-Pancreatic isease Referred to ndoscopic Retrograde Cholangiopancreatography Rodrigo A. Rodrigues, rmelindo. Libera, Ana Guimaraes, Angelo Ferrari, Stephan Geocze ASG Poster Session AM-5:00 PM Hall F RCP BILIARY T1478 T1479 ndoscopic Sphincterotomy Versus ndoscopic Papillary Balloon ilatation for Choledocholithiasis in Liver Cirrhosis with Coagulopathy o Hyun Park, Myung-Hwan Kim, Sung Koo Lee, Sang Soo Lee, Moon Hee Song, Jung Sik Choi, ong Wan Seo, Young I1 Min Failed Biliary RCP: A Prospective Multicenter Study of Risk Factors, Complications, and Resource Utilization avid G. Perdue, Martin L. Freeman, RCOST Study Group P-226

33 r POSTR SSSIONS--CLINICAL SCINC T1480 T1481 T1482 T1483 T1484 T1485 T1486 T1487 T1488 T1489 T1490 T1491 Is the Complication Rate the Same for Index Versus Repeat Biliary Sphincterotomy? Isaac Raijman St., Susana scalante-glorsky What is the Best Patient's Position uring RCP? A Prospective Randomized Trial Comparing Prone vs. Supine Position Vittorio Terruzzi, Franco Radaelli, Gianmichele Meucci, Giorgio Minoli ndoscopic Snare Papillectomy of Ampullary Tumors: 10-Year Review of 55 Cases at Indiana University Medical Center Chiliang Cheng, Stuart Sherman, van L. Fogel, Lee McHenry, James L. Watkins, Toyomi Fukushima, Glen A. Lehman ndoscopic Therapy in Primary Sclerosing Cholangitis (PSC) -- oes the Complication Risk Outweigh Therapeutic Benefit? Satyananda Kumar Vuddagiri, Renee France, Richard Kozarek Prospective Study of Value of 1 and 6 hr Amylase, Lipase Levels in the Prediction of Post RCP Pancreatitis (PP) Following Sphincterotomy of Pancreatic Segment (PS) of Sphincter of Oddi Suku George, Jeffrey. Linder, Joseph. Geenen, Marc F. Catalano Why o We Fail at RCP? Pavan Manchikalapati, Shyam Varadarajulu, Charles M. Wilcox Prospective Analysis of Pancreatic Sphincterotomy as a Pre-cut Technique Michel Kahaleh, Stephen J. Bickston, Jeffrey Tokar, Tarun Mullick, Paul Yeaton Severe Post-RCP Pancreatitis May Become (Almost) xtinct Paul R. Tamasky ndoscopic Retrograde Cholangiopancreatography (RCP) in Patients 80 years of Age and Older: Safe and ffective va Fritz, Andreas Kirchgatterer, ietmar Hubner, Gerhard Aschl, Maximilian Hinterreiter, Bernhard Stadler, Peter Knoflach arly Complication of ndoscopic Biliary Stenting in Patients with Inoperable Malignant Biliary Stricfure Sang Woo Cha, Jong Ho Moon, Young eok Cho, Bung Min Ko, Young Koog Cheon, Young Seok Kim, Yun Sou Kim, Joon Seong Lee, Moon Sung Lee, Chan Sup Shim, Boo Sung Lee Post-RCP Pancreatitis: oes Prophylactic Pancreatic uct Stent Placement Reduce the Risk? avid J. Novak, Lotika Sharma, Franca B. Barton, Firas A1- Kawas Recurrent Pyogenic Cholangitis (RPC): Characteristics and Outcomes from Patients Undergoing ndoscopic Retrograde Cholangiograms Robert nns, Jack Amar, onald Carr ASG Poster Session AM-5:00 PM RCP BILIARY T1492 T1493 T1494 T1495 T1496 T1497 T1498 T1499 T1500 T1501 T1502 T1503 ~lo~io1 Convol[iotl L club'; ndoscopic Transpapillary Laser I ithotripsy Llsing FRY (Frequency oubled ouble Pulsed Nd:~ +~G Laser) Technology for ifficult Connnon Bile uct Stones Tae Hyeon Kim, Sang Wook Kim, joo ]in "~com, clc-t~taa "ttl, Seo, Suck Chei Choi, Yong-Ho Nah xtracorporeal Shock Wave Lithotripsy (SWL) and ndoscopic Management of Intrahepatic Lithiasis Gianluca Spera, Cristiano Spada, Massimiliano Mutignani, Vincenzo Perri, Andrea Tringali, Pietro Familiari, Guido Costamagna etection of Small Bile uct Stones by Intraductal US in Patients with Highly Suspected Choledocholithiasis Showing No Filling efect on RCP Jong Ho Moon, Sang Woo Cha, Young Koog Cheon, Young Seok Kim, Young eok Cho, Jin Oh Kim, Yun Sou Kim, Joon Seong Lee, Moon Sung Lee, Hae Kyung Lee, Chan Sup Shim, Boo Sung Kim Clinical Usefulness of Intradnctal US for Clarification of Small Filling efect on RC in Patients with Suspected Choledocholithiasis Sang Woo Cha, Jong Ho Moon, Young eok Cho, Bung Min Ko, Young Koog Cheon, Young Seok Kim, Yun Sou Kim, Joon Seong Lee, Moon Sung Lee, Hae Kyung Lee, Chan Sup Shim, Boo Sung Kim ndoscopic Papillary Balloon ilation for Secondary Bile uct Stones in Young Patients Jong Ho Moon, Sang Woo Cha, Young Koog Cheon, Young S ok Kim, Young eok Cho, Yun Sou Kim, Joon Seong Lee, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim ndoscopic Balloon ilation of the Biliary Sphincter Compared to ndoscopic Biliary Sphincterotomy for Removal of Common Bile uct Stones uring RCP: A Meta-analysis of Randomized, Controlled Trials Todd Baron, Gavin Harewood An Angulated Common Bile uct Predisposes to Recurrent Bile uct Stones After ndoscopic Stone xtraction aniel Keizman, Maya Ish Shalom, Fred M. Konikoff The Inflated-Balloon-Pulling Method Is a Useful Method for stimating the Safe Upper Margin of ndoscopic Sphincterotomy (st) Hyun-Jun Kim, Sang-Heum Park, Suck-Ho Lee, Hong-Joo Kim, II-Kwun Chung, Hung-Sou Kim, Sun-Joo Kim MRCP Vs RCP: A Comparative Study in iagnosis of Common Bile uct Stones Luigi T. Familiari ndoscopic Management of Recurrent Pyogenic Cholangitis: A Single Center Retrospective Review lizabeth Cruz, Karen C. Bagatelos, Paul S. Chard, Sinda M Mein, Fernando Velayos, James W. Ostroff Safety and fficacy of ndoscopic Sphincterotomy and Bile uct Clearance in Patients with Acute Cholangitis ue to the Common Bile uct Stones Neven Ljubicic, Luka Rotkvic Outcome After Failure of Initial Mechanical Lithotripsy (ML) of Biliary and Pancreatic Stones Suku George, Isaac Raijman, Joseph. Geenen, Marc F. Catalano P-227

34 T U S A Y MAY 18 T1504 T1505 T1506 T1507 Intraoperative RCP for the Management of Choledocholithiasis: A Comparative Study Luis R. Rabago, Maria elgado, Cristina de Vicente, Ignacio Moral, Nuria Ventosa, Jose Luis Castro, Jaime Vazquez cbarri, Rosa Llorente, Jose Romeo, Francisco Gea, Jose Luis Martinez Veiga ilated ucts: Is It a Reliable Sign for Choledocholithiasis in Patients with Acute Biliary Pancreatitis (ABP)? Affan Qua&i, Marc F. Catalano, Joseph. Geeneu Risk Factors for Choledocholithiasis in a High-Risk Population with Symptomatic Gallstone isease Aldo A. Garza, Wendy K. Ayala, Cynthia A. Becerra, Jose A. Castellanos, Hector J.J. Maldonado-Garza Long-Term Stenting for Choledocholithiasis Carlos Barrientos ASG. Poster Session AM-5:00 PM Hall F RCP BILIARY T1508 T1509 T1510 T1511 T1512 T1513 Argon Plasma Coagulation for istal Migration or Improper Placement of Self-xpanding Metal Stents (SMS) rik Springer, S. R. Nash, Raj J. Shah, Mainor R. Antillon, Yang K. Chen ffectiveness of a New, Long Cytology Brush in the valuation of Malignant Biliary Obstruction: Final Results of a Prospective Study van L. Fogel, Mario ebellis, Lee McHenry Jr., James L. Watkins, Suzette Schmidt, Stuart Sherman, Glen A. Lehman Small Sphincterotomy Combined with Papillary ilation with Large Balloon Permits Retrieval of Large Stones Without Crushing Them Atsushi Minami, Takao Okuyama, Shinji Hirose Removal of Self xpandable Metallic Wallstents Michel Kahaleh, Jeffrey Tokar, Tri Le, Paul Yeaton Precut Papillotomy Using a New Sphincterotome (Iso- Tome) Sang-Heum Park, Hyun-Jun Kim, Suck-Ho Lee, Hong-Joo Kim, Hong-Soo Kim, Sun-Joo Kim Randomized Control Trial of ST with ither ndoeut Mode or Conventional Pure Cut Mode Mitsuhiro Kida, Hidehiko Kikucht, Masao Araki, Miyoko Takezawa, Maya Watanabe, Yoshiki Kida, Hiroshi Imaizumi, Katsunori Saigenji ASG Poster Session AM-5:00 PM " Hall F RCP PANCRAS T1514 T1515 Covered Wallstent for the Management of Malignant Biliary Obstruction Yousuke Nakai, Hiroyuki Isayama, Yutaka Komatsu, Takesbi Tsujino, Nobuo Toda, Naoki Sasahira, Natsuyo Yamamoto, Kenji Hirano, Minoru Tada, Kawabe Takao, Masao Omata Yield of Pancreatic Juice Cytology (PJC) in the iagnosis of Strictures of the Pancreas uct James L. Watkins, van L. Fogel, Lee McHenry, Laura Lazzell-Pannell, Suzette Schmidt, Harvey Cramer, John M. Chappo, Julia Leblanc, John ewitt, Stuart Sherman, Glen A. Lehman POSTR SSSIONS--CLINICAL SCINC ASG Poster Session AM-5:00 PM Hall F RCP PANCRAS T1516 T1517 T1518 T1519 T1520 US-Guided Pancreatic Pseudocyst rainage: Comparison with Standard ndoscopic Cystenterostomy Marc F. Catalano, Suku George, Miriam Thomas, Meng Hua, Joseph. Geenen Factors Predictive of Resolution in Pancreatic Pseudocyst Treated ndoscopically Michel Kahaleh, Thomas Rockoff, Stephen Bickston, Cynthia Yoshida, Vanessa M. Shami, Paul Yeaton ndoscopic Transmural rainage of Pancreatic Fluid Collections in Outpatients Christopher M. Gibbs, Todd H. Baron ndoscopic rainage of Large Bi-Lobular Pancreatic Pseudocyst in an Adolescent Using Combined US- Assisted Cystduodenostomy and US-Guided Cystgastrostomy All T. Nawras, Surinder S. evgun, Michael J. Finnegan, Kevin Gaylord Surgical Treatment Is More ffective Than Percutaneous rainage for Pancreatic Pseudocysts--Long Term Follow-up of Patients with Pancreatic Pseudocyst After rainage Steven Keilin, Qiang Cai, Ammar Ghazale ASG Poster Session AM:5:00 PM Hall F RCP PANCRAS T1521 T1522 T1523 T 1524 T1525 T1526 Pancreatoscopy with lectrohydraulic Lithotripsy (HL): Primary or Adjunctive Therapy for Pancreatic Stones? Raj J. Shah, aniel A. Langer, Mainor R. Antillon, Yang K. Chen Symptomatic Pancreatic uct (P) Strictures: Result of uctal ilation and Serial Stenting Meng Hua, Miriam Thomas, Marc F. Catalano, Joseph. Geenen Long-Term Outcome of Pancreatic uct Stone Removal in Patients with Chronic Pancreatitis Omar Khan, Suku George, Joseph. Geenen, Marc F. Catalano 108 Cases of Pancreatolithiasis Treated by SWL + ndoscopy: Mainly about 67 Cases Treated by PB (ndoscopic Pancreatic uct Balloon ilation): Its Usefulness and Safety Tadao Tsuji xtracorporeal Shock-Wave Lithoptripsy for Pancreatic Calculi: A 10-year xperience at a Single U.S. Center Lee McHenry, James L. Watkins, Kenyon Kopecky, van L. Fogel, Chi-Liang Cheng, Anne. Kochell, Lee Ann Shelly, Stuart Sherman, Suzette Schmidt, Thomas J. Howard, Laura Lazzell-Pannell, Glen A. Lehman oes the Addition of Balloon ilatation to Stent Insertion ecrease Recurrence of Pancreatic uct Stricture in Patients with Chronic Pancreatitis? Sang Soo Lee, Myung-Hwan Kim, Sung Koo Lee, ong- Wan Seo, o Hyun Park, Jeong Sik Choi, Young-I1 Min P-228

35 r POSTR SSSIONS--CLINICAL SCINC T1527 The fficacy of Pancreatic Stenting for Management of Pancreatic Stones Naoki Sasahira, Yutaka Komatsu, Hiroyuki Isayama, Yosuke Nakai, Natsuyo Yamamoto, Kenji Hirano, Takeshi Tsujino, Nobuo Toda, Minoru Tada, Takao Kawabe, Tetsuo Katamoto, Ryo Nakata, Masao Omata ASG Poster Session AM-5:00 PM Hall F RCP PANCRAS Pancreas ivisum: 3-6 Years Follow-up After ndoscopic T1528 Therapy Mohammad Alsolaiman, Peter Cotton, Robert Hawes Is the Rate of Iatrogenic Acute Pancreatitis the Same T1529 with Manipulation of the Major Papilla Versus Minor Papilla? Isaac Raijman Sr., Susana scalante-glorsky, Marc Catalano, Atilla rtan Is Incomplete Pancreas ivisum Merely a Normal T1530 Anatomic Variant Without Clinical Implications? Terumi Kamisawa, Masami Yoshiike, Naoto gawa, Hitoshi Nakajima, Atsutake Okamoto ndoscopic valuation of the Minor Papilla Prior to T1531 Pancreatography at RCP: A Prospective Study Christopher Lawrence, ouglas A. Howell, Andreas M. Stefan, Frank J. Lukens Minor Papillotomy in Pancreas ivisum: o T1532 Complications and Restenosis Rates iffer Between Use of the Needle Knife Papillotome(NKS) vs. Ultratapered Traction Sphincterotome(UTS)? Jamie Berkes, Sandee Bemklau, Allan Halline, Rama Venu, Russell Brown ASG Poster Session AM-5:00 PM Hall F RCP PANCRAS T1533 T1534 T1535 T1536 T1537 Predictors of Outcome in Pancreatic uct isruption Managed by ndoscopic Stenting Shyam Varadarajulu, Radu Tutuian, Mark Payne, Robert H. Hawes, Peter B. Cotton Morbidity and Mortality of RCP-induced Severe Acute Pancreatitis Santhi Swaroop Vege, Suresh T. Chari, Bret T. Petersen, Todd H. Baron Sr., Joanna R. Jones, Padma N. Munukuti, Mauricio Zapiach Predictors for Severity of Post-RCP Pancreatitis Linda S. Lee, Christopher C. Thompson, John Saltzman, William R. Brugge, Rie Ookubo, avid L. Carr-Locke There Are Benefits of Overnight Observation After Outpatient RCP Jeffrey. Linder, Paul R. Tarnasky isconnected Pancreatic Tail Syndrome (PTS): Clinical Features, Management, & Outcome Christopher Lawrence, ouglas A. Howell, Andreas M. Stefan, onald. Conklin, Frank J. Lukens, Ronald F. Martin, Andrew Landes, Becky Benz ASG Poster Session AM-5:00 PM Hull F ~Jo~ial Convention COl/C/ RCP PANCRAS Patent Accessory Pancreatic uct Prevent Post-RCP T1538 pancreatitis Terumi Kamisawa, Naoto gawa, Hitoshi NakajimL1. Atsutake Okamoto ASG Poster Session AM-5:00 PM Hall F RCP PANCRAS T1539 T1540 T1541 T1542 The Use of Corticosteroids in the Prevention of RCP- Induced Pancreatitis: A Meta Analysis Ma Cecilia M. Sison, Jade. Jamias, Ma Lourdes O. aez ndoscopic Treatment for Main Pancreatic uct Rupture Following Silastic Ring Vertical Banded Gastroplasty Marianna Arvanitakis, Reza Chamlou, Myriam elhaye, Celso Matos, Jean Closset, Jacques eviere RCP with ndoscopic Sphincterotomy (S) in Acute Biliary Pancreatitis (ABP). 6 Year Review of Outcomes Chad Gonzales, William B. Silverman ndoscopic Interventions and Jejunal Feeding in the Management of Acute Biliary Pancreatitis Tibor Gyokeres, Maria Burai, szter Schafer, Richard Schwab, Akos Pap ASG Poster Session AM-5:00 PM Hall F ' RCP PANCRAS T1543 ndoscopic Minor Papilla Interventions in Patients Without Pancreas ivisum Moon Hee Song, Myung-Hwan Kim, Sung Koo Lee, ong Wan Seo, Sang Soo Lee, o Hyun Park, Young ll Min ASG Poster Session AM-5:00 PM Hall F RCP PANCRAS T1544 T1545 T1546 Pancreatographic Findings of Idiopathic Acute Pancreatitis Terumi Kamisawa, Naoto gawa, Masami Yoshiike, Hitoshi Nakajima, Atsutake Okamoto Techniques for Pancreatic Sphincterotomy; Lack of xpert Consensus Mohammad Alsolaiman, Peter Cotton, Robert Hawes, Giuseppe Aliperti, avid L. Carr-Locke, van L Fogel, Martin L. Freeman, Gregory G. Ginsberg, ouglas A. Howell, Richard A. Kozarek, Glen L. Lehman, Lee McHenry, Stuart Sherman, James Watkins, Charles M. Wilcox Idiopathic Recurrent Pancreatitis (IRP): oes It Progress to Chronic Pancreatitis? Miriam Thomas, Marc F. Catalano, Joseph. Geenen T1547 Management of Pancreatic Pleural ffusion,ascites and xternal Pancreatic Fistulae by ndoscopic Retrograde Pancreatography and Nasopancreatic rain Placement eepak K. Bhasin, Ismail Siyad, Surinder Rana, Babu R. Thapa, Ujjal Poddar, Birinder Nagi P-229

36 T U S A Y MAY 18 T1548 T1549 T1550 Relationship Bewteen the Radiological Anatomy and Patency of the Accessory Pancreatic uct: ye-injection RP Study Temmi Kamisawa, Naoto gawa, Masami Yoshiike, Hitoshi Nakajima, Atsutake Okamoto ndoscopic Treatment of Pancreatic Ascites Isaac Raijman Sr., Susana scalante-glorsky, Hashim Khandawalla, Steven Glorsky, Craig Fischer ndoscopic Feature of Gastric Varices Caused by Left- Sided Portal Hypertension due to Pancreatic isease Tadayuki J. Takagi, Atsushi Irisawa, Katsutoshi Obara, Ayako Saito, Goro Shibukawa, Go Yamamoto, Takuto Hikichi, Takeru Wakatsuki, Hidemichi Imamura, Yukio Sato ASG Poster Session AM-5:00 PM Hall F US T1551 T1552 T1553 T1554 lnterventional ndoscopic Ultrasound Cholangiography: Report of Five Cases Michel Kahaleh, Cynthia Yoshida, Vanessa M. Shami, Paul Yeaton A Prospective Multi-centre Study of the Safety and Accuracy of Combined ndoscopic Ultrasound (US) - guided Fine Needle Aspiration (FNA) and Trucut Needle Biopsy (TNB) William Tam, Guru Aithal, Jeremy ean, Stephen P. Pereira xperimental Study of ndoscopic Ultrasound Guided thanol Injection in the Pancreas ; Novel Strategy for Pancreatic Lesion Reiko Ashida, Kenji Yamao, Kakuya Matsumoto, Kenji Okubo, Akira Sawaki, Nobumasa Mizuno, Kazuhide Hlguchi, Tetsuo Arakawa Control of Traumatic Chylothorax with US-Guided Thoracic uct Injection Sclerotherapy avid H. Robbins, Mark Block, avid Lewin, Michael Wallace, Brenda Hoffman ASG Poster Session AM-5:00 PM Hall F US T1555 T1556 T1557 T1558 Prediction of Recurrence of sophageal Varices Following ndoscopic Treatment Using Color oppler ndoscopic Ultrasonography Shoryoku Hino, Hiroshi Kakutani, Keiichi Ikeda, Kazuki Sumiyama, Yujiro Uchiyama, Akira Kuramochi, Yoko Kitamura, Muneo Kawamura, Hisao Tajiri, Mitsuyoshi Urashima Large Series Western uropean xperience with the Olympus MH908 Slim-Probe Shows Greater Complete Staging of sophageal Cancer Without the Need for ilatation Charles Vu, Laura oig, Simon Anderson, Steven Tsang, John Meenan The Accuracy of US Staging as Compared to Laparoscopic Staging of sophageal Cancer Neeraj Kaushik, Asif Khalid, ebra Brody, James Luketich, Kevin McGrath ndosonographic Staging of Obstructive sophageal Cancer: How Far Should We Go? Jan-Wemer Poley, Sarwa arwish Murad, Jelle Haringsma, Marian L. Hordijk, Hugo W. Tilanus, rnst J. Kuipers POSTR SSSIONS--CLINICAL SCINC T1559 T1560 T1561 T1562 T1563 T1564 T1565 T1566 T1567 T1568 us Assessment of the Tumor Response After Concomitant Radiochemotherapy in sophageal Cancer. iagnostic and Prognostic Implications Pascal Burtin, Chantal Milan, Olivier Bouche, Marc Giovannini, Michel Pelletier, Thierry Conroy, Olivier Ruget, Laurent Bedenne A Prospective Comparative Study of Staging Accuracy Rates for Nurse Performed US in sophageal Cancer John Meenan, Laura oig, Charles Vu, Simon Anderson Large Series Prospective xperience with US for Post- Chemotherapy Staging of sophageal Cancer. Time to Answer the Question of Clinical Value John Meenan, Laura oig, Charles Vu, Simon Anderson etailed Analysis of the iagnostic Operating Characteristics of ndoscopic Uhrasonography (US) in Patients with sophageal Cancer Hirofumi Shirakawa, Nozomu Kobayashi, Takuji Gotoda, Takahiro Kozu, aizou Saitou, Roy Soetikno A Prospective, Blinded Trial Comparing the Accuracy of PT, US and CT with Resection Pathology in the Staging of sophageal Cancer Following Neo-Adjuvant Chemotherapy John Meenan, Charles Vu, Sheila Rankin, Peter Harper Role of ndoscopic Ultrasound xamination in Predicting Curative Resection Status of Advanced sophageal Cancer: A Prospective Study Mohandas K. Mallath, Harish Peshwe, Shesta Mehta, Mukta Ramadwar, Rajesh Mistry The etection of Unsuspected Liver Metastases uring US Staging of Cancer of the sophagus and Cardia Asif Khalid, ebra Brody, James Luketich, Kevin McGrath Utility of sophagoprobe Guidewire Manipulation in Imaging the Celiac Axis Region for Staging of Stenotic sophageal Carcinoma Shiro Urayama; Jason L. Umphress Is It Worthwhile to valuate Pancreas in Patients Undergoing Staging US for sophageal Cancer? Sudhanshu Gogia, Mike Bismar, Brian Collins, Arlene M. Correa, Linus Ho, Banke Agarwal ndoscopic Ultrasound (US) of the sophageal Wall in Patients with Non Cardiac Chest Pain (NCCP) ric M. Ward, Massimo Raimondo, Timothy A. Woodward, Sami R. Achem ASG Poster Session AM-5:00 PM Hall F US T1569 T1570 T1571 Possible Role of US-FNA in the iagnosis of Tuberculosis Ray Shidrawi, Kamini Patel, Mark Pelling, Loong-Yuan Han, Annette Fritscher-Ravens US Features of Mediastinal Tuberculosis: A PCR Based Cytodiagnosis by Trans-esophageal US-FNA Pampudi V. J. Sriram, Arthur J. Kaffes, P. Rajasekhar, R. Vijaikumar, Mohd. Mateen, Gudur V. Rao, uvvuru Bhaskar Red@, uvvuru Nageshwar Reddy iagnosing Sarcoidosis by ndoscopic Ultrasound Guided Fine Needle Aspiration (US-FNA) Jouke T. Annema, Maud Veselic, Klaus F. Rabe P-230

37 POSTR SSSIONS--CLINICAL SCINC T1572 T1572A T1572B Prospective Comparison of US, PT and CT Scan for Staging Lung Cancer: Preliminary Analysis Mandeep Sawhney, Amy Holmstrom, Robert Kratzke, KathlTn Rice, Suruchi Kaul, ouglas Nelson, Rosemary Kelly ndoscopic Ultrasound-Guided Fine Needle Aspiration of the Left Adrenal Gland in Patients with Thoracic or Gastrointestinal Malignancies Mohamad A. loubeidi, Stefan Seewald, Ashutosh Tamhane, Boris Brand, Victor Chen, Ichiro Yasuda, Robert Cerfolio, Salem Omar, Theodoros Topalidis, Charles Mel Wilcox, Nib Soehendra ndoscopic Ultrasound-Guided Fine Needle Aspiration Biopsy Combined with Flow Cytometry in the iagnosis of Suspected Mediastinal or Retroperitoneal Lymphoma Mohit Mehra, Ashutosh Tamhane, Mohamad A. loubeidi ASG Poster Session AM-5:00 PM US T1573 T1574 T1575 T1576 T1577 T1578 Hall F Assessment of Clinical Impact of ndoscopic Ultrasound on Rectal Cancer Gavin Harewood, Michael Lew, Jonathan Clain ffect of Biopsy on ndoscopic Ultrasound Staging of Rectal Tumors Marco Sailer, Ruediger Goertz, ieter Bussen, Martin Fein ndoscopic Ultrasound (US) Staging of Rectal Cancer: iagnostic Accuracy Before and Following Chemoradiation Benjamin Avidan, Moshe Nadler, Iris Barshack, Yaakov Maor, Simon Bar-Meir nhanced Sensitivity for etecting Malignant Lymphadenopathy in Rectal Cancer When Linear US Is Added to Radial US: Impact on Patient Management Michael J. Le W, Tony. Yusuf, Jonathan. Clain, Gavin C. Harewood, lizabeth Rajan, Mark. Topazian, Kenneth K. Wang, Maurits J. Wiersema, Nicole L. Pochron Value of US-Guided Fine Needle Aspiration via Rectum for the iagnosis of Recurrent Rectal Carcinoma and Peri-Rectal Malignant Tumors Atsushi Irisawa, Manoop S. Bhutani, Takuto Hikiohi, Goro Shibukawa, Tadayuki J. Takagi, Go Yamamoto, Takeru Wakatsuki, Hidemichi Imamura, Yukie Yamada, Katsutoshi Obara, Yukio Sato Misinterpretation of ndoscopic Ultrasonography Re- Staging After Preoperative Radiochemotherapy in Rectal Cancer: Preliminary Results Carlo Fabbri, Luca e Luca, Sandro Macchia, Francesco Salvi, Vincenzo Cennamo, Antonio Piemontese, anilo Baroncini, Paola Billi, Maria Pia Foschini, Antonio Maestri, Giovanni Frezza, Alessandro Repici, Nicola 'Imperio T1580 T1581 T1582 T1583 T1584 T1585 T1586 T1587 T1588 T1589 A 360 Radial lectronic choendoscope: A New Technology in ndoscopic Ultrasound (US) Andrea N. Culliford, Charles J. Lightdal< Sta\'ros N Stavropoulos, Peter. Stevens Virtual Pancreatoscopy Using Three-dimensional ndoscopic Uhrasonography Senju Hashimoto, Yoshiki }qirooka, Akihiro hob Tctuh,tn,, hoh, Hiroki Kawashima, Kazuo Hara, Akira Kanam~,l t. Naoki Ohmiya, Yasuo Niwa, Hidemi Goto erived M-mode Uhrasonography: A Valuable Imaging Modality for the Visual Assessment of sophageal Motility Valmik Bhargava, Hwoon-Yong Jung, Vikas Bhalla, James L. Puckett, Jianmin Liu, Ravinder K. Mittal The Sonobrush: A Novel US-Guided Biopsy evice for Pancreatic Masses Seng-Ian Gan, Brenna R. Bounds, Martha Pitman, William R. Brugge Computer-Assisted Analysis of US Images for Parenchymal and Border ifferences in Pancreatic Mass Lesions Nina Phatak, Nuzhat Ahmad, Gregory Ginsberg, Chandra Sehgal, Michael Kochman valuation of a Prototype ual Transducer Radial choendoscope avid H. Robbins, Brenda Ferguson, Brenda Hoffman, Robert Hawes Initial xperience of High-Frequency Ultrasound Probe Sonography Using a Multi-Bending Scope Shigeto Yoshida, Shinji Tanaka, Toshiki Yamaguchi, Akira Fukumoto, aisuke Kamino, Madoka Nakao, Kayoko Kunihiro, Yutaka Mitsuoka, Hideharu Okanobu, Shiro Oka, Noriaki Manabe, Yasuhiko Kitadai, Norihiko Hayakawa, Kazuaki Chayama The Accuracy of ndoscopic Ultrasound (US)-Guided Fine Needle Aspiration (FNA) for iagnosing Solid Pancreatic Lesions Using a New 25-Gauge Needle System Sammy Ho, Robert Bonasera, Hazar Michael, Bonnie Pollack, James Grendell, Mala Gupta, Martin Feuerman, Simcha Pollack, Frank Gress Intraductal Ultrasound of the Pancreato-biliary System Using ual Plane Reconstruction Yu-Jeong A. Choi, Stavros Stavropoulos, Savreet Sarkaria, Charles Lightdale, Peter. Stevens One Step ndoscopic rainage of Pancreatic Pseudocysts: Use of a New Therapeutic cho ndoscope Riad R. Azar, Frank J. Quayle IV, ayna arly, Cara L. Kohlmeier, Steven A. dmundowicz ASG Poster Session AM-5:00 PM Hall F ASG Poster Session AM-5:00 PM US T1579 Hall F A New sophageal Variceal Pressure Measurement evice Larry S. Miller, Qing ai, June Park, Stephanie Irizarry, Tung Nguyen, Vinod Thangada, lan Miller, Joseph Kim US T1590 T1591 US FNA Is More Sensitive Than CT/US FNA for iagnosing Pancreatic Malignancy: A Randomized Controlled Trial John. Horwhat, Kevin McGrath, Robert A. nns, Helen Stiffler, M. Stanley Branch, John Baillie, rik K. Paulson, Paul Jowell The Negative Predictive Value (NPV) of ndoscopic Ultrasound (US) in a Large Series of Patients with Suspected Pancreatic Cancer Jason B. Klapman, Kenneth J. Chang, Phuong T. Nguyen P-231

38 POSTR SSSIONSmCLINICAL SCINC T1592 New ndoscopic Ultrasound (US) Criteria for iagnosis of Chronic Pancreatitis (CP) nrique Vazquez-Sequeiros, aniel Boixeda, Victor Moreira, Antonio Gracia Plaza T1606 Predictors of Accuracy in Patients Undergoing ndoscopic Ultrasound (US) Guided Fine Needle Aspirate (FNA) of the Pancreas Richard Zubarik T1593 etection of K-ras Point Mutation Increases the fficacy of US-FNA for the iagnosis of uctal Pancreatic Adenocarcinoma Fauze Maluf-Filho, Marcia S. Kubrusly, Jose duardo M. da Cunha, Paulo Sakai, Jose Jukemura, Andre Montagnini, Marcel C. C. Machado, Shinichi Ishioka T1607 Clinical and ndosonographic Predictors of the Number of US-FNA Passes of Solid Pancreatic Masses: A Prospective Multivariable Analysis in 300 Consecutive Cases Mohamad A. loubeidi, Ashutosb Tamhane, Charles M. Wilcox T1594 T1595 T1596 T1597 Assessment of Telomerase Activity in Samples Obtained from Pancreatic Lesions by ndoscopic Ultrasound Guided Fine Needle Aspiration (US-FNA) Is Clinically Useful Girish Mishra, oug Case, Mary Zhao, avid Bridgers, Ben Pineau, John Sweeney, Kim Geisinger, Simon Bergman, James Cappellari IV, Coty Ho, Susan Melin, Russel Howerton, d Levine, Perry Shen, Jamal Ibdah A Prospective valuation of Tandem US and RCP as a Single Procedure Jake Matlock, Shawn Mallery, Rebecca Lai, Martin Freeman Prospective Comparison of US, RCP, and US- Guided True Cut Biopsy (US-TCB) for Suspected Chronic Pancreatitis John ewitt, Kathleen McGreevy, Julia LeBlanc, Lee McHenry, Glen Lehman, van Fogel, Bill Cummings, Stuart Sherman Malignant Mediastinal Lymphadenopathy in Patients with Pancreatobiliary Cancer Banke Agarwal, Sudhanshu Gogia, Arlene M. Correa, Linus Ho, Brian T. Collins T1608 T1609 T1610 T1611 Assessment of Benign and Malignant Biliary Strictures with Three-dimensional ndoscopic Intraductal Ultrasound William Tam, Johannes Wittmann, Adrian R. W. Hatfield, Stephen P. Pereira Usefulness of Contrast-nhanced ndoscopic Uhrasonography in the iagnosis of Biliary iseases Yosbiki Hirooka, Akihiro Itoh, Senju Hashimoto, Terutomo ltoh, Hiroki Kawashima, Kazuo Hara, Akira Kanamori, Naoki Ohmiya, Yasumasa Niwa, Hidemi Goto A Prospective Study of the Yield of ndoscopic Uhrasound-Guided Fine-Needle Aspiration in Patients with Malignant-Appearing Biliary Strictures with Negative RCP Bile uct Brush Cytology Lee McHenry, van U Fogel, James L. Watkins, Mario de Bellis, Julia LeBlanc, John ewitt, John Chappo, Harvey Cram'er, Stuart Sherman, Lois Bucksot, Laura Lazzell- Pannell, Suzette Schmidt, Glen A. Lehman Can the US Nodal Assessment Predict the Cytopathological Type of Pancreatic Tumors? Jason B. Klapman, Kenneth J. Chang, Phuong T. Nguyen ndosonographic and Histopathological Staging of xtrahepatic Bile uct Cancer: o We Need a New TNM-Classification? irk omagk, Raihana iallo, Christopher Poremba, Christina Schleicher, Agnes Bankfalvi, Wolfram omschke, Josef Menzel In Room Cytopatologist Adequacy. Is It mandatory uring ndoscopic Ultrasonography Fine Needle Aspiration? Paolo G. Arcidiacono, Marzia Rossi, Gianni Mezzi, Pieralberto Testoni T1598 T1599 T1600 T1601 T1602 Impact of Needle Size on Pancreatic FNA Cytology John G. Kuldau, Richard obhan, Thomas J. Savides, Cynthia Behling Transcript Heterogeneity in Pancreatic Cancer Revealed by Microarray xpression Profiling erived from US- FNA Tissue Shiro Urayama, Albert Truong An ndoscopic Pancreatic Function Test (epft) Can ecrease Frequency of Negative US in valuation of Patients with Chronic Abdominal Pain (CAP) arwin Conwell, Gregory Zuccaro Jr., John Vargo, John umot, Frederick VanLente, Patricia Trolli Prospective Trial of Intraductal Uhrasonography for valuation of Unclear RCP Findings Till Wehrmann, Ksenia Martchenko, Nikos Stergiou Usefulness of p53 Immunostaining in Fine-Needle Aspiration Biopsy Specimens for iagnosis of Pancreatic Cancer Takao Itoi, Kazuto Nakamura, Atsushi Sofuni, Fumihide Itokawa, Kazuhiro Kakimi, Jun Atsushi, Fuminori Moriyasu T1612 T1613 T1614 T1615 ndoscopic Ultrasound and Computer Tomography Are Inaccurate Methods of Classifying Cystic Pancreatic Lesions Henning Gerke, Tracy A. Jaffe, Robert M. Mitchell, Michael F. Byrne, Helen Stiffler, M. Stanley Branch, John Baillie, Paul S. Jowell Pre-Operative Identification of Malignancy in Cystic Lesions of Pancreas by US-FNA Banke Agarwal, Mike Bismar, Sudhanshu Gogia, Linus Ho, Arlene M. Correa, Brian T. Collins T1603 US: An Ideal Initial Test for lderly Patients with Idiopathic Pancreatitis Karin M. Rettig, Allan G. Halline, Russell. Brown, Rama P. Venu T1616 Benign Pancreatic Cystic Neoplasms: oes F/U US- FNA Confirm or Alter the iagnosis Marc F. Catalano, Suku George, Miriam Thomas, Meng Hua, Joseph. Geenen T1604 T1605 ndosonography (US) for etection of Anomalous Union of the Pancreaticobiliary uct (AUPB) in Patients with Asymptomatic Gallbladder Wall Thickening Bong Min Ko, Sang Woo Cha, Young Seok Kim, Jong Ho Moon, Young eok Cho, Yun Soo Kim, Joon Seong Lee, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim Usefulness of ndoscopic Ultrasonography in the ifferentiation Between Malignant and Benign Causes of Thickened Gallbladder Wall on Lee, Sung Koo Lee T1617 T1618 iagnostic and Therapeutic Guidelines for ndoscopic Treatment of Common Bile uct Stones in Cholecystectomized Patients avorin ajcman A Comparison of Sampling Techniques of Suspected Malignant Biliary Strictures Sanjeev M. Wasan, Madhukar Kaw P-232

39 r POSTR SSSIONS--CLINICAL SCINC N00 T1619 T1620 T1621 T1622 T1623 T1624 T1625 T1626 T1627 T1628 Focal or iffuse "Fullness" of the Pancreas on CT Is Usually Benign, but the Yield of Malignancy, Albeit Small, Justifies US +/- FNA John. Horwhat, Henning Gerke, John Baillie, M. Stanley Branch, Paul Jowell A Comparative Study of iagnostic Value of Cytologic Sampling by US-Guided Fine Needle Aspiration and that by RP for the Management of Pancreatic Mass Without Biliary Stricture Takeru Wakatsuki, Atsushi Irisawa, Takuto Hikichi, Goro Shibukawa, Takuto J. Takagi, Go Yamamoto, Hidemichi Imamura, Katsutoshi Obara, Yukio Sato o Stents Reduce the iagnostic Yield of US-FNA in Malignant Strictures? Gregory Olds, Pankaj Singh, Stacie Vela, eepak Agrawal, Boolchand Vikram, Ananya as, Gerard Isenberg, Richard C. K. Wong, Michael V. Sivak, Ashish Sharma, Ahmed Khan, Amitabh Chak Long Term Outcome in Patients with ndosonographic Findings Suggestive of Mild Chronic Pancreatitis Pankaj Singh, Stacie Vela, eepak Agrawal, Gregory Olds, Vikram Boolchand, Ananya as, Gerard Isenberg, Richard C. K. Wong, Michael V. Sivak Jr., Ashish Sharma, Ahmed Khan, Amitabh Chak ndoscopic Ultrasound-Guided Fine Needle Aspiration of Solid Pancreatic Masses: A Learning Curve Mohamad A. loubeidi, Ashutosh Tamhane, Charles M. Wilcox US-FNA of Proximal Biliary Strictures After Negative Tissue Sampling at RCP John ewitt, Vijay Misra, Julia LeBlanc, Stuart Sherman, Lee McHenry, Kathleen McGreevy Clinical valuation of Biliary Tract Lesions in Autoimmune Pancreatitis Using lntraductal Ultrasonography Yuta Nakamura, Junji Yoshino, Kazuo Inui, Takao Wakabayashi, Kazumu Okushima, Hironao Miyoshi, Saburo Nakazawa iagnostic Yield of Standard Brush Cytology (BC) Versus US-FNA for Pancreatic Cancer with Associated Malignant Biliary Stricture. Is It Time to Bury the Standard Biliary Brush? Kirk Bernadino, Stuart R. Gordon, ouglas J. Robertson US as an Adjunct to RCP for the iagnosis of Malignant Pancreaticobiliary uct Stricture Pankaj Singh, Stacie Vela, eepak Agrawal, Gregory Olds, Vikram Boolchand, Gerard Isenberg, Richard C. K Wong, Michael V. Sivak Jr., Ashish Sharma, Ahmed Khan, Stavan P. Parmar, Amitabh Chak Accuracy of ndoscopic Ultrasound, Fine Needle Aspiration, Cytology, and Cyst Fluid Tumor Markers in Patients with Pancreatic Cystic Lesions: Comparison with Surgical Pathology and 12-month Follow-up Abdulrhaman M. A1-Jebreen, Rafael Perini, Francis Sutherland, Joseph Romagnuolo ~-SG Poster Session ~:00 AM-5:00 PM :-US T1629 Hall F US Meets VOXL-MAN a 3- Anatomical Animation of Longitudinal ndoscopic Ultrasound (L-US) ike Burmester, Thomas Leineweber, Silke Hacker, Ulf Tiede, Jens Niehaus, Thomas Huetteroth T1630 T1631 T1632 T1633 T1634 T1635 T1636 T1637 T1638 T1639 T1640 T1641 T1642 Frequency and Significance of Acute lntracystic Hemorrhage uring US-Guided Fine Needle Aspiratim~ Shyam Varadarajulu, Charles M. Wilcox, Mohan/ad loubeidi ndoscopic l~hrasound (US) Compared with ndoscopy and Transabdominal Uhrasound (TUS) m the Work-up of Patients with Upper Ahdominal Pain (UAP): A Prospective Muhi-Center Cohort Study Kenneth J. Chang, Amitabh Chak, Charles Lightdale. Kenneth Binmoeller, Yang K Chen, Richard A. /kk>,~> Grego U C. Albers, Michael V. Sivak, Phuong Ng~/>eu. ]~,hu G. Lee, Gerard A. Isenberg, Richard C. K Wong A Prospective Study of the Current Utilization Patterns of US by Clinical Gastroenterologists Miriam Thomas, Girish Mishra, Amitabh Chak, Maurits Wiersema, ileen Robinson, Naresh T. Gunaramam Practice Patterns and Attitudes Towards Role of US in Staging of GI Malignancies: A Survey of Physicians and Surgeons Nuzhat A. Ahmad, Karl Kim, Michael Kochman, Gregory G. Ginsberg US-Guided Needle Aspiration (US-FNA) in Subepithelial Intramural GI-Tract Masses (SIGIM): Results in 105 Lesions Shawn Mallery, Rebecca Lai, Ricardo Bardales, dward Stelow, Steven ebol, Michael Stanley ndoscopic Ultrasound-Guided Fine-Needle Aspiration Cytology of Mediastinal Lymph Nodes: Therapeutic Impact in Patients with Pancreatobiliary and Gastric Neoplasias Ignacio Femandez-Urien, Jose Carlos Subtil, Maite Herraiz, Maite Betes, Susana de la Riva, duardo spinet, Cristina Carretero, Miguel Munoz-Navas, Maria olores Lozano Yield of Tissue Sampling for Submucosal Lesions valuated by US: A Comparison Between Forceps Biopsies and ndoscopic Submucosal-Mucosal Resection Michael J. Cantor, Raquel. avila, ouglas O. Faigel ndoscopic Ultrasound-Guided Fine Needle Aspiration of Left Adrenal Gland Masses Mazen Alsatie, John ewitt, Julia LeBlanc, Lee McHenry, Stuart Sherman, John Chappo Assessment of Knowledge of the Application and Utility of ndoscopic Ultrasound Among Physicians and Surgeons Tony. Yusuf, Gavin C. Harewood, Jonathan. Clain, Michael J. Levy, Kenneth K. Wang, Mark. Topazian, lizabeth Rajah A First Report of Tumor Seeding by US-FNA Sarto C. Paquin, Tju Siang Chua, Genevieve Tessier, Gilles Gariepy, Ginette Raymond, Raymond Bourdages, Anand Sahai A New Method to Assess the Adequacy of Trucut Core Biopsy Specimens Brian C. Jacobson, Irina ubinchik, Niall Swan Prospective valuation of On-Site FNA Cytology Analysis vs Final Cytology Analysis in US Cases Glen Arluk, Olga Ioffe, Anna Berry, Pat Bourquin, Bruce Greenwald, Peter arwin Improving the Accuracy of Ultrasound-ndoscopy Fine- Needle Aspiration (US-FNA): Factors Predicting a Correct iagnosis and Usefulness of an Attendant Pathologist Maria Pellise, Angels Gines, Mane1 Sole, iana Vera, Gloria Femandez-sparrach, Antoni Castells, Alfredo Mata, Josep Llach, Josep Maria Bordas, Josep Maria Pique P-233

40 T U S A Y MAY 18 T1643 T1644 T1645 A Prospective Study Comparing ndoscopy and ndoscopic Uhrasonography (US) in the valuation of GI Subepithelial Masses Joo Ha Hwang, Steven Shaw, Hubert H. Nietsch, Stephen J. Rulyak, Michael. Saunders, Michael B. Kimmey A Prospective valuation of US-Guided Celiac Plexus Block in Patients with Chronic Pancreatitis and Pancreas Cancer Julia K. LeBlanc, John ewitt, Lee McHenry, Stuart Sherman, Thomas Imperiale, dith Collins ndoscopic Ultrasound-Guided Fine-Needle Aspiration Cytology (US-FNA): Factors Predicting iagnosis Accuracy and Number of Passes Necessary to Obtain Adequate Specimens Jose Carlos Subtil, Ignacio Fernandez-Urien, Maite Betes, Maite Herraiz, Susana e la Riva, duardo spinet, Cristina Carretero, Miguel Munoz-Navas, Maria olores Lozano POSTR SSSIONSmCLINICAL SCINC T1653 FG-PT Imaging of Gastrointestinal Stromal Tumors: Correlation with Histopathological Findings by Using US-FNA Masahiro Yamada, Yasumasa Niwa, Yoshiki Hirooka, Nobuhiro Ando, Fumiyuki Miyata, Ryouji Miyahara, Akira Ohashi, Tsuguo Kamioka, Shusuke Kitabatake, Masanao Nakamura, Naoki Ohmiya, Akihiro Itoh, Hidemi Goto ASG Poster Session AM-5:00 PM Hall F US T1646 T1647 T1648 T1649 T1650 T1651 T1652 Unexplained Thickened Folds on CT: oes G Help Select Patients for US? A Prospective Analysis ric Lam, Rayburn Rego, Sarto C. Paquin, Tju Siang Chua, Genevieve Tessier, Ginette Raymond, Anand Sahai Preoperative iagnosis of GISTs Using ndoscopic Uhrasonography Guided Fine Needle Aspiration Biopsy (US-FNAB) Akira Sawaki, Kenji Okubo, Nobumasa Mizuno, Reiko Ashida, Tsuneya Nakamura, Masahiro Ta3ika, Hiroki Kawai, Kenji Yamao Fine Needle Aspiration (FNA) vs. ndoscopic Mucosal Resection (MR) -- Optimizing Tissue Acquisition uring ndoscopic Ultrasound (US) valuation of Submucosal Lesions Hansen Kwok, Phuong T. Nguyen, John G. Lee, Catherine J. Christie, Kenneth J. Chang Impact of ndoscopic Ultrasound (US) on Management of Patients with Large Gastric Folds and ndoscopic Biopsies Negative for Malignancy (LGF-NB) Maria Pellise, Angels Gines, Alejandro Membrillo, Gloria Fernandez-sparrach, Maria Teresa Soria, Antonio Soriano, Alfredo Mata, Josep Llach, Josep Maria Bordas, Josep Maria Pique ndoscopic and choendoscopic valuation of Gastric Varices radication with Cianoacrilate rika Macedo, Fernanda Thuler, Veruska i Sena, Gustavo e Paulo, Frank Nakao, Jose Ardengh, Angelo P. Ferrari Jr. The Accuracy of ndoscopic Ultrasonography as Further xamination valuating the epth of Invasion of Gastric Cancer Yosuke Otake, Takuji Gotoda, Takahiro Kozu, Ichiro Oda, aizo Saito Clinicopathologic Study of Gastric Submucosal Tumor: ndosonographic and Immunohistochemical Findings of Gastrointestinal Stromal Tumors (GISTs) in Stomach Bong Min Ko, Su Jin Hong, Kye Won Kwon, Chang Beom Ryu, Joo Young Cho, Joon Seong Lee, Moon Sung Lee, Chan Sup Shim, Boo Sung Kim P-234

41 POSTR SSSIONS--COMBIN SCINC COMBIN SCINC AASL Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pro. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F HCV PATHOGNSIS T1654 ~Ti655 T1656 T1657 T1658 T1659 T1660 T1661 T1662 T1663 T1664 Cancer Cofactor Role for HBV X Protein in HCV Pathogenesis Victor V. Keasler, Charles R. Madden, Stanley Lemon, Milton Finegold, Betty L. Slagle The Los Alamos Hepatitis C Sequence atabase Carla Kuiken, Russell Richardson, Karina Yusim Antiviral Properties of Pegylated Versus Non-Pegylated Interferon Alpha-2b Against Hepatitis C in Cell Culture Virendra Joshi, Karim Awad, Cesar Fermin, Srikanta ash Hepatic Inflammatory Cytokine mrna xpression in Hepatitis C Virus (HCV) and HCV/Human Immunodeficiency Virus (HIV) Co-infected Patients Chenhui Zhang, Preeti Golia, Ira M. Jacobson, Andrew H. Talal istribution of Insulin Resistance and Variability of Insulin Action in HCV Infection Mandana Khalili, Fahim Abbasi, Peter Bacchetti, Gerald Reaven, Jackie Maher Smoking Is Associated with Increased Fibrosis and Vascular ndothelial Growth Factor (VGF) in Patients with Chronic Hepatitis C (CHC) Anouk T. ev, Lawrence Blatt, Julie Rae, ylan Matzinger, Keyur Patel, John G. McHutchison ffects of Cytokine Gene Polymorphism on Histological Activity Index in Patients with Chronic Hepatitis C Genotype 3 Zaigham Abbas, Tariq Moatter, Akbar S. Hussainy, Wasim Jafri Cellular and Lobular istribution of Hepatic Iron in African-American vs.caucasian Patients with HCV Gagan K. Sood, Charu Subramony, iana Little, Maher Azzouz ffects of Pegylated Interferon-~ on Bright and im Natural Killer Cell Activation in Chronic Hepatitis C Infection Amy Lin, Stevan A. Gonzalez, Susan Marshall, April Tignor, Tina Ha, Gary orante, Ira M. Jacobson, Susanna Cunningham-Rundles, Andrew H. Talal TNF Receptor Family Members Are Upregulated Late uring IFNa Therapy for Hepatitis C Katherine M. Kinmer, Jeff Browning, Frances Phillips, Geri Brown Comparison Study of Prometheus FIBROSpect II to Knodell and Ishak Fibrosis Scores in Alaska Native Hepatitis C Patients Carol Christensen, Steve Livingston, ana Bruden, Heike ubner, Katie Smith, Jason o, sther Oh, Brian McMahon T1665 T1666 T1667 T1668 T1669 T1670 T1671 T1672 T1673 T1674 Insulin Resistance in HCV Infection: Impact of HCV Genotype Mandana Khalili, Fahim Abbasi, Peter Baccheui, Jackic Maher, Gerald Reaven Progression of Fibrosis in Chronic Hepatitis C Treated with Interferon or Interferon and Ribavirin. Impact of Co-factors: Alcohol, Steatosis, Iron Serum Markers Fatima Serejo, Adilia Costa, Jose Velosa, Miguel C Xl~,u:,u Maria J. Lacerda Analysis of Relationship Between Mutations in Nonstructural 5A Region of Hepatitis C Virus and Response to Interferon Using Amino Acid Substitution Matrices Jin-Wook Kim Increased Hepatic xpression of Insulin-Like Growth Factor I Receptor (IGF-IR) in Chronic Hepatitis C Jose T. Stefano, Maria Lucia C. C. Giannella, Marcel C. C. Machado, aniel Giannella-Neto Impairment of imer Formation of Interferon Regulatory Factoro3 by Hepatitis C Virus Core Protein Leads to vade Interferon System Kazuaki Inoue, Michinori Kohara, Makoto Yoshiba A Functional Polymorphism of the Stromelysin Gene (MMP 3) May Influence isease Progression in Hepatitis C Viral Infection Conor O'Brien, Margaret O'Brien, Cliona O'Farrelly, John Hegarty, Peter onaldson Role of uctular Metaplasia in Pathogenesis of Cirrhosis in HCV Tuan. Nguyen, Samuel W. French, Wendell Tang, Nan Li, Magdelena e Leon Liver Steatosis in Chronic Hepatitis C. The Importance of Co-factors: BMI, Alcohol, Lipids and Serum Markers of Iron Storage Fatima Serejo, Adilia Costa, Jose Velosa, Miguel C. Moura, Maria J. Lacerda C8 + Lymphocytes Are an Important Source of RANTS Secretion in Hepatitis C Virus Infection Jacob Nattermann, Hans ieter Nischalke, Golo Ahlenstiel, Georg Feldmann, Tilman Sauerbruch, Ulrich Spengler Specific Inhibition of Hepatitis C Virus Replication by Cyclosporin A Naoya Sakamoto, Mina Nakagawa, Yoko Tanabe, Nobuhiko Kanazawa, Shinya Maekawa, Tomoyuki Koyama, Yoshie Takeda, Nobuyuki nomoto, Mamoru Watanabe AASL Poster Session AM-5:00 PM Hall F HPATOTOXICITY CLL ATH, INFLAMMATION, RUG MTABOLISM, TOXICITY AN OXIATIV STRSS The Anti-Apoptotic Protein Mclol Mediates Interleukin-6 T1675 Induced Survival of Human Malignant Cholangiocytes Valorie Chiasson, Fanyin Meng, Linda Brooks, Tushar Patel T1676 PT Imaging of Hepatitic Apoptosis in BF-1 Mice Using 124I-Annexin V Bronwyn ekker, Heather Keen, Lynn isley, avid Hastings, Sue Lyons, Nigel Smith, Jamal Zweit, Alastair J. M. Watson enotes W Poster of istinction P-235

42 POSTR SSSIONSmCOMBIN SCINC T1677 T1678 T1679 T1680 T1681 T1682 T1683 T T1685 TI686 T1687 T1688 T1689 Glutathione (GSH) epletion by the Toxic Bile Acid Chenodeoxycholate (CCA) Sesitizes Primary Cultured Mouse Hepatocytes to Tumor Necrosis Factor-Alfa (TNF-Alfa) Induced Apoptosis Hidenari Nagai, Katsuhiko Matsumaru, Koichi Momiyama, Koji Ishii, Kazumasa Miki, Yasukiyo Sumino irect Activation of PKC~x Induces Apoptosis in Cholangiocarcinoma Shannon Glaser, Julie Venter, Silvia Taffetani, Jo Lynne Phinizy, Heather Francis, Ramona Reichenbach, Giammarco Fava, Gianfranco Alpini A Novel Selective A2A Adenosine Agonist Prevents Concanavalin A-Indiced Liver Injury by Inhibition of C4 T Cell Activation and Proliferation Masaru Odashima, Michiro Otaka, Sumio Watanabe 13-Glucan Treatment Protects Against Buru-Induced Hepatic and Intestinal Oxidative Injury in Rats Hale Z. Toklu, Nermina Jahovic, Berrak C. Yegen, Goksel Sener Modulation if Cytokine Activity in Humans by Potential Therapeutic Agents for Alcoholic Hepatitis Rehan Khan, Shirish Barve, Rashmita Sahoo, Swati Joshi- Barve, Craig McClain, aniell Hill Kupffer Cell epleted Rats Have a iminished Acute Phase Response Following Major Liver Resection Hubert Prins, Paul van Leeuwen The Role of Kupffer Cells After Major Liver Surgery Hubert Prins, Paul van Leeuwen Constitutive and Inducible xpression of mrp2 (ABCC2) Gene Is Regulated by the Cellular etoxification Pathway AR-Nrf2 in the Mouse Liver Valeska Vollrath, Mirentxu Iruretagoyena, Jose Chianale Gut-Liver Relationship: Frequently a Forgotten Feature in Clinical Practice Alessandro Federico, Concetta Tuccillo, Fulvia Terracciano, Mauro Valeriano 'Auria, Claudio e Simone, Camillo el Vecchio Blanco, Carmela Loguercio Antiapoptotic Activity of Idoxifene and stradiol Through strogen Receptor-13 in Cultured Rat Hepatocytes Tatuzo Itagaki, Ichiro Shimizu, Mina Itonaga, Xinliang Cheng, Katutaka Sannomiya, Hirohito Honda, Susumu Ito Increased theno-na Adducts in the Liver and Urine Of Patients with Alcoholic Liver isease Jagadeesan Nair, Alexander Frank, Claudia Haas, Helmut K. Seitz, Helmut Bartsch Fatal rug-induced Liver Injury in Sweden inar Bjornsson, Pernilla Jerlstad, Roll Olsson Mycophenolate Mofetil for rug-induced Vanishing Bile uct Syndrome S. S. Jakab, William Hale, A. B. West, Robert S. Brown Jr. AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary GNTIC ISASS AN GN THRAPY T Trans-Complementing Replicating Vectors May Reduce Liver Toxicity in Adenovirus-Based Gene Transfer Therapies in the Treatment of Malignant Tumors Gemot W. Wolkersdoerfer, W. J. Ramsey, John Morris, Stephan Miehlke, Gerhard hninger T T1692 T1693 Abnormal Hepatocystin Caused by Truncating PRKCSH Mutations efines Autosomal ominant Polycystic Liver isease Joost P. H. renth, sa Tahvanainen, Rene H. M. te Morsche, Pia Tahvanainen, Helena Kaariainen, Krister Hockerstedt, Jiddeke M. van de Kamp, Martijn Breuning, Jan B. M. J. Jansen Treatment with SCH 58235, an Inhibitor of Intestinal Sterol Absorption, Reduces Plasma Plant Sterol Levels, but Stimulates Cholesterol Synthesis in Sitosterolemic Wild-Type Kyoto (WKY) Rats Ashok K. Batta, Guorong Xu, Sarah Shefer, Gerald Salen Attenuation of Acute Liver Injury of Mice by Hepatocyte Growth Factor Gene Transfer to the Liver via Tail Vein Takayasu Hanawa, Kenji Suzuki, Yusuke Kawauchi, Yasunobu Matsuda, Hiroyuki Yoneyama, Hiroki Maruyama, Gi ong Han, Hiroshi Kawachi, Fujio Shimizu, Jun-lchi Miyazaki, Hitoshi Asakura, Yutaka Aoyagi AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary LIVR AN BILIARY CARCINOMA: TIOLOGY, IAGNOSIS, AN NATUILAL HISTORY Clinical Usefulness of lsfluorodeoxyglucose-positron T1694 mission Tomography in Cholangiocarcinoma Chang Mo Moon, Byung Kyu Park, Seungmin Bang, Young Soo Park, Seung Woo Park, Si Young Song, Mi Jin Yun, Jong oo Lee, Jae-Bock Chung, Jin-Kyung Kang The Role in the Hepatocarcinogenesis of Antibody to T1695 Hepatitis B Core Antigen in Patients with HBsAg Negative Chronic Liver isease Hironori Tanaka IV, Yoshiyuki Iwasaki, Yoshiyuki Kobayashi, Shinichiro Nakamura, Nobuyuki Toshikuni, iji Matsumoto, Yasuhiro Miyake, Hideki Ohnishi, Kohsaku Sakaguchi, Yasushi Shiratori, Kazuhiro Nouso Functions of the Cdk inhibitor p27 in Cholestatic Liver T1696 Injury Katherine Jelinek, Jinwen W. ing, Aleksandra J. Poole, Angela L. Tyner istinguishing Benign and Malignant Focal Liver T1697 Lesions by Kupffer Imaging with Sonographic Contrast Agent, Levovist Shinpei Sato, Haruhiko Yoshida, Ryousuke Tateishi, Takuma Teratani, Tomonori Fijtshima, Shuntaro Obi, Miho Kanda, Yuuji Kondo, Noriyo Yamashiki, Takashi Ishikawa, Takao Kawabe, Shuichirou Shiina, Masao Omata Use of Fourier Transform Mid-Infrared (FT-IR) T1698 Spectroscopy for the Rapid Intraoperative iagnosis of Gallbladder Cancer L.-M. Yang, Z. Xu, X.-S. Zhou, Q.-B. Li, Roger. Soloway, J. S. Wang, Y.-Z. Xu, J.-G. Wu, Y. Ren, W.-H. Li Survival Benefit of Screening for Hepatocellular T1699 Carcinoma: Screening in Patients with Chronic Liver isease Hironori Tanaka, Yoshiyuki Kobayashi, Shinichiro Nakamura, Nobuyuki Toshikuni, iji Matsumoto, Yasuhiro Miyake, Hideki Ohnishi, Kazuhiro Nouso, Yoshiaki Iwasaki, Kohsaku Sakaguchi, Yasushi Shiratori ifferent ffects of the Functional MCP-1 Polymorphism T1700 (A-2518G) on Hepatic Fibrosis and Hepatocancerogenesis Matthias Froh, Marcus Muehlbauer, Felix Stickel, Helmut K. Seitz, Amdt Hartmann, Thomas Weiss, Juergen Schoelmerich, Claus Hellerbrand P-236 enotes W Poster of istinction

43 v POSTR SSSIONS--COMBIN SCINC T1701 T1702 T1703 T1704 Neuroendocrine-like ifferentiation in Hepatocellular and Pancreatic Cancers T 1711 Mary K. McStay, Korsa Khan, Kay Savage, Mark Stubbs, Amar P. hillon, Martyn Caplin Superiority of CT uring Arterial Portography(CTAP) and CT Hepatic Arteriography(CTHA) for etecting Hepatocellular Carcinoma T1712 Hideki Ohnishi, Kohsaku Sakaguchi, Bon Shoji, iji Matsumoto, Hironori Tanaka, Shinichiro Nakamura, Yoshiyuki Kobayashi, Kazuhiro Nouso, Yasushi Shiratori Contrast-nhanced ynamic Ultrasonography(C-US) ifferentiates Hepatocellular Carcinoma from ysplastic T1713 Nodules: Correlation with Histological Grading Yoshiyuki Kobayashi, Shinichiro Nakamura, Nobuyuki Toshikuni, Hironori Tanaka, iji Matsumoto, Hideki Ohnishi, Kazuhtro Nouso, Kousaku Sakaguchi, Yasushi Shiratori T1714 Cost-Utility Analysis of Hepatocellular Carcinoma Screening Program in Patients With Chronic Liver isease Hironori Tanaka, Yoshiyuki Kobayashi, Shinichiro Nakamura, Nobuyuki Toshikuni, iji Matsumoto, Yasuhiro T1715 Miyake, Hideki Ohnishi, Kazuhiro Nouso, Yoshiaki Iwasaki, Kohsaku Sakaguchi, Yasushi Shiratori AM-5:00 PM Hall F T1716 gponsored by: sophageal, Gastric and uodenal isorders GR PATHOGNSIS Motor Behaviour of the Infrajunctional Portion of the T1705 Proximal Stomach in Patients with Gastroesophageal T1717 Reflux isease Luiz. A. Troncon, Carolina L. A. Barbieri, J. Ruver L. Herculano Jr., Lilian R. O. Aprile, Roberto O. antas T1718 T1706 T1708 Transient Lower sophageal Sphincter Relaxations (TLSRS) Are the Major Mechanism of Gastroesophageal Reflux, but TLSRS Are Not the Cause of Reflux sophagitis Katsuhiko Iwakiri, Yoshinori Hayashi, Makoto Kotoyori, Yuriko Tanaka, Akihiko Kawakami, Choitsu Sakamoto The Secondary Peristaltic Response to Air in Patients T1707 with ndoscopic-negative GR Is Very Low, Compared with That of Healthy Subjects Katsuhiko Iwakiri, Yoshinori Hayashi, Makoto Kotoyori, Yuriko Tanaka, Akihiko Kawakami, Choitsu Sakamoto T1709 T1710 Abdominal Obesity, Not Obesity per se, Is an Independent Risk Factor for the Severity of rosive sophagitis Giampaolo Iacopini, Alessandro Vitale, Giuseppe Villotti, Lucia d'alba, Stefano Frontespezi, Maria Assunta e Cesare, Federico Iacopini The ffect of Meal Content, Gastric mptying and Gastric PH on the Postprandial Acid xposure of the Lower sophageal Sphincter (LS) Anand P. Tamhankar, Tom R. emeester, Jeffrey H. Peters, Jeffrey A. Hagen, Steven R. emeester, John Lipham, Cedric G. Bremner ssential Role of Pepsin in Pathogenesis of Acid Reflux sophagitis in Rats Kenji Nagahama, Masanori Yamato, Kazuhiro Fukushima, Shinichi Kato, Koji Takeuchi T1719 T1720 T1721 T1722 ffect of Selective COX-2 Inhibition in a Rat Model of sophageal Adenocarcinoma lena Piazuelo, Carnlclo Ccln-i,m.,\lfrcdn Fscarlin, ]~\ i~1 Ortego, Pilaf Jimenez, Francisco sleva, Mark Strutqk, Asuncion Garcia, Angel Lanas Reflux in the Morbidly Obese: Are S)mploms a Good Predictor? Brintha Krishnamoorthy, Chri-~ Boniquit, I~} B. Pa\ >t,,~\,,i.\ Timothy S. Kuwada, rvin enham, Alexander P x::@c Peter J. Kahrilas, John. Pandolfino Hydroxyl Ions Are Potent lnhibitors of Ion Transporl in Rabbit sophageal pithelium Nelia A. Tobey, Chris M. Argote, Taylan Kav, Roy C. Orlando How o ndoscopy Positive and ndoscopy Negative Gastroesophageal Reflux iseases iffer? Prospective valuation of Patients with Gastroesophageal Reflux isease (GR) Jan Martinek, Marek Benes, Tomas Hucl, Julius Spicak Simultaneous Assessment of Gastric mptying, Postprandial Gastric Acid Secretion and Acid or Weakly Acidic Gastroesophageal Reflux aniel Sifrim, Michiel Verfaillie, Patrick Flamen, Jan Tack, Jiri Silny, Jozef Janssens II-1 Beta Pro-Inflammatory Polymorphisms and Gastric Atrophy Reduce Risk of Gastro-sophageal Reflux isease Takafumi Ando, Kazuo Nobata, Kenji Ina, Osamu Watanabe, Masaaki Minami, Kazuo Kusugami, Naoki Ohmiya, Yasumasa Niwa, Yasuyuki Goto, Nobuyuki Hamajima, mad 1-Omar, Hidemi Goto ifferences in the Mechanisms of Gastroesophageal Reflux Between Mild and Severe Reflux sophagitis Yoshinori Hayashi, Katsuhiko Iwakiri, Makoto Kotoyori, Akihiko Kawakami, Choitsu Sakamoto Pepsin etection in the Lungs of Transplant Patients: vidence of Gastric Refluxate Iain A. Brownlee, Chris Ward, Ian Forrest, Gall Pritchard, esmond Murphy, John ark, Paul A. Corris, Jeff P. Pearson MnSO Gene Polymorphism Predisposes to the evelopment of Gastroesophageal Reflux isease Leon M. G. Moons, Peter. Siersema, Joost van elft, rnst J. Kuipers, Aad Knaapen, Han Geldof, Willem A. Bode, Ralph Gottschalk, Arnoud H. M. van Vliet, Jos C. S. Kleinjans, Johannes G. Kusters Relationship Between Helicobacter Pylori Genotypes and Gastroesophageal Reflux isease (GR) Kwong M. Fock, Tiing L. Ang, Subbiah hamodaran, ng Kiong Teo, Jessica Tan, Lian H. Gan, Tay M. Ng The Influence of Gastroesophageal Pressure Gradients in Patients with Gastroesophageal Reflux isease Chih-Cheng Hsieh, Giuseppe Portale, Anand Tamhankar, Jeffrey A. Hagen, Jeffrey H. Peters, Chadin Tharavej, Tasha A. K. Gandamihardja, aniel Vallbohmer, Cedric G. Bremner, Tom R. emeester Frequency Analyses of sophageal ph Recordings etect Novel Relationships and emonstrate the Arbitrary Basis of Time ph<4 and the xistence of sophageal Reflux pisodes Jerry. Gardner, Sheldon Sloan, Malcolm Robinson, Philip B. Miner Jr. enotes W Poster of istinction P-237

44 T U S A Y MAY 18 T1723 T1724 T1725 T1726 T1727 T1728 T1729 T1730 T1731 T1732 T1733 T1734 T1735 T1736 POSTR SSSIONS--COMBIN SCINC Pancreatic Proteases Retain Activity Through Stomach- Like Conditions, and Increase Oesophageal amage by T1737 Pepsin lain A. Brownlee, Jo L. Hart, Matt P.. ore, ave I. Fenton, Peter W. ettmar, Jeff P. Pearson Pathophysiology of Gastro-oesophageal Reflux iseases T1738 in Chinese - Role of Transient Lower Oesophageal Sphincter Relaxation and Oesophageal Motor ysfunction Wai-Man Wong, Kam-Chuen Lai, Wai-Mo Hui, Wayne H. C. Hu, Jia Qing Huang, Nina Y. H. Wong, Harry H. X. Xia, Annie O. O. Chan, Shiu-Kum Lain, Benjamin C. Y. Wong Helicobacter Pylon Infection and sophagitis in T1739 Children -- Is There an Association? Yoram litsur, Zandra Lawrence Intra-abdominal Fat is a Risk Factor for Barrett's sophagus T 1740 Peter Kvapil, Joan Hacken, Hashem B. l-scrag Prolonged Retention of Proximal Gastric Pool in GR: Is tlsrs a Main Factor of sophageal Acid xposure? A Pilot Study abo Xu, Meiyun Ke, Mingwei Qin, Wenbin Mu, Zhang Xu, Zhifeng Wang, Wenfan Shang, Xuanping Xia T1741 The Acidity of Postprandial Gastroesophageal Reflux is etermined by the Rate of Gastric mptying aniel Sifrim, Michiel Verfaillie, Patrick Flamen, Jan Tack, Jiri Silny, Jozef Janssens ffects of Hiatal Hernia and of Peristaltic ysfunction on Intraesophageal istribution of Refluxed Acid in GR Patients Sara merenziani, Fortunee I. Habib, Mentore Ribolsi, Michele P, L. Guarino, Renato Caviglia, Tommasangelo Petitti, Michele Cicala Gastric mptying and Postprandial Gastric Acidity aniel Sifrim, Jerry. Gardner, )(in Zhang, Jan Tack, Jozef Janssens T1742 The ffect of xercise on the sophageal Body and III Lower sophageal Sphincter in Normals and Patients ~k~ with Gastroesophageal Reflux isease (GR) k,j Kuldip S. Banwait, enise M. Harnois, ennis Tighe, Leo C. Katz, avid M. Kastenberg T 1743 Not ating Close to Bedtime - Is This Good Advice? The Relationship Between inner and Supine Reflux Marc R. Happe, Corinne L. Maydonovitch, Lavem S. Belle, k,/ Andrew C. Gorske, Roy K H Wong istinctive Gene xpression Profile in isease-free T1744 Mucosa of Patients with Chronic sophagitis Irshad All, Howard Jacob, Walter Hogan, Tanya Rittmann, Shailesh Bajaj, Reza Shaker Nocturnal Patterns of Supine Reflux T1745 Alistair L. King, Angela Anggiansah, Terry Wong, Roy Anggiansah Trypsin Activates Human sophageal pithelial Cells to Produce Inflammatory Cytokines Through Proteaseactivated Receptor 2 Norimasa Yoshida, Kazuhiro Katada, Masaaki Kuroda, T1746 Makoto Shimozawa, Kazuhiko Uchiyama, Yuji Naito, Takeshi Okanoue, Toshikazu Yoshikawa, Toshiya Soma, Yutaka Shimada ifferences of Clinical Characteristics Between Patients with Symptomatic GR and Reflux sophagitis in Japan Yasuhiro Fujiwara, Kazuhide Higuchi, Masatsugu Shiba, Kazuki Yamamori, Kazunan Tominaga, Toshio Watanabe, Nobuhide Oshitani, Takayuki Matsumoto, Tetsuo Arakawa T1747 Silent Gastroesophageal Reflux in Patients with Otolaryngologic Symptoms Angel Alvarez-Sanchez, nrique Rey, Cristina Alba, Manuel iaz-rubio Oxidative NA amage and Its Repair nzyme xpression in Chronic sophagitis Induced by Gastrojejnnal Reflux in Rats Masaaki Kuroda, Yuji Naito, Kazuhiko Uchiyama, Yutaka Isozaki, Makoto Shimozawa, Kazuhiro Katada, Tomohisa Takagi, Hiroshi Ichikawa, Naoyuki Sakamoto, Norimasa Yoshida, Toshikazu Yoshikawa The Scleroderma LS: vidence for Impairment of Smooth and Skeletal Muscle Components Alishia A. Saunders, Kuldip S. Banwait, Anthony imarino Jr., Sidney Cohen The Poor Symptom Response to Proton Pump Inhibitors (PPIs) in Non-rosive GR Results from Resistance of Meal-Stimulated Gastric Acid Secretion to PPIs, Not Increased sophageal Acid Sensitivity Jerry. Gardner, Hugo Gallo-Torres, Sheldon Sloan, Malcolm Robinson, Philip B. Miner Jr. A New Theory to xplain the Pathophysiology of GR. Pharmacological Separation of the Gastro-sophageal Junction High Pressure Zone (GJHPZ) emonstrates an Absent Gastric Sling Fiber Pressure Profile in Patients with GR Larry S. Miller, Brasseur James, Rhys Ulerich, Beje Thomas, Amonia Thomas, Qing ai AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology PRVNTION AN CHMOPRVNTION Gefitinib and Sulindac Have an Additive ffect on Inhibition of MUC2 and MUC5AC Mucin xpression in Human Colon Cancer Cells lizabeth Half, YunJie Sun, Nachman Mazurek, James Byrd, Robert S. Bresalier NSAIs Activate in Human Colon Cancer Cells Genes ncoding PTN, Protein Kinase Phosphatases MKP-3 and PTPNll, and Caspase 3: Novel Mechanisms of NSAIs Chemopreventative Action ric C. Chu, Jianyuan Chai, Andrzej Tarnawski Inhibition of Src Signaling by Sulindac Sulfide via Induction of C-terminal Src kinase in HT-29 Cells Ramesh K. Wall Sr., Jennifer Koetsier, hananjay Kunte, Hemant K. Roy Cholic Acid and Chemopreventive Ursodeoxycholic Acid Cause Opposing ffects on Ras and Cox-2 in AOM Tumorigenisis and Human Colon Cancer Cells Sharad Khare, Greg Cohen, Reba Mustafi, Sonia Cerda, Ramesh Wall, Inshu Khare, Hana Holubec, avid arnest, Sohrab Mobarhan, Marc Bissonnette Opposing Changes in PKC-8 xpression by Chemopreventive ( o-3) and Tumor-promoting ( o-6) Fatty Acids in Caco-2 Cells: Role of iacylglycerol (AG) Sonia R. Cerda, Maria Tretiakova, Reba Mustafi, Xavier Llor, C. V. Rao, Marc Bissonnette Involvement of p53 in Selenomethionine Induced Apoptosis in Human Colon Cancer Cells: Implications for Chemopreventive Strategies Ajay Goel, Florentine Fuerst, C. Richard Boland P-238 ~ enotes W Poster of istinction

45 v I'1748 T1749 POSTR SSSIONS~COMBIN SCINC NSAIS Inhibit Oxidation of Glutamate in Rat Liver Mitochondria T1760 Michael J. Garle, Bruce Middletonn, Christopher Hawkey Conjugated Linoleic Acid (CLA) Up-Regulates p21 ~pvwm xpression in Colon Cancer Cells: A Mechanism for the Growth Inhibitory ffect of CLA Jung H. Y. Park, o Y. Lira, Angela L. Tyner T1761 AM-5:00 PM Sponsored by: Gastrointestinal Oncology TRANSLATIONAL RSARCH III Hall F Sporadic Colorectal Cancers Lacking hmlh1 and with "][r1750 MicrosateUite Instability Show Functional p53 and High xpression of Thymidilate Synthase: Implications for Clinical Settings and Chemotherapeutic Strategies Luigi Ricciardiello, Claudio Ceccarelli, Graziella Angiolini, Giuseppe N. Martinelli, nrico Roda, Franco Bazzoli Colonic Crypt Stem Cell Mutation Indices (CCSCMI) in T1751 a Predictive Risk Assessment Model for iet Related Chemicals ilish T. onnelly, Helen Bardwell, Gerry A. Thomas, dward. Williams, Margaret Hoper, Paul Crowe, William G. McCluggage, avid H. Phillips, Martin Osborne, Alan Hewer, Michael Stevenson, Frederick C. Campbell Identification and Validation of ifferentially xpressed T1752 Genes in Colon Tumors of Min Mice William M. hrhardt, Xiaodi Chen, William F. ove Ileal Carcinoids Over-xpress the Fibrosis-Related T1753 Peptide, CTGF Michael Shapiro, Mark Kidd, Kevin. Lye, William Usinger, John Murren, Irvin M. Modlin ownregulation of Pim-1 Protein Kinase uring T1754 Colorectal Cancer Progression Antonia R. Sepulveda, Leena Lourduraj, Simona i Caro, Antonio Gasbarrini, Swaminathan Rajendiran Immunoselection/RT-PCR Based Assay for Specific T1755 etection of Circulating Colon Cancer Cells: A Pilot Study Nirmala Gonsalves, Joseph P. Muldoon, Karen L. Kaul, Randall. Brand, Malcolm M. Bilimoria, wa Gliwa, Mohammad Tajuddin, Ramesh Walt, Nancy Sands, Aamair Tajuddin, Kathy Mangold, Hemant K. Roy The Gene Coding for Secreted Phosphoproteinl/ T1756 Osteopontin Is the Most Consistently Overexpressed Gene in Cholangiocarcinoma as etected by Oligonucleotide Arrays Holger Hass, Juergen Jobst, Michael Gregor, Andrea Frilling, Stephan Kaiser etection of Colorectal Cancer : Faecal MGMT Gene T1757 Methylation harmendra K. Garg, Amanda Coupe, lizabeth A. Williams, Nigel Belshaw, Ian T. Johnson, avid M. Bradburn, John C. Mathers ffect of Taurocholate Feeding on 7ot-ehydroxylating T1758 Bacterial Levels in Mice: Potential Implication in Colon Carcinogenesis Jason M. Ridlon, Sean. McGarr, Phillip B. Hylemon Rectal Mucosal Nuclear Chromatin Patterns in Patients T1759 at Risk for Colonic Adenomas and Adenocarcinomas James R. Ranger-Moore, Peter H. Bartels, Janine inspahr, Teresa A. Brenmall, enise H. Frank, avid S. Alberts, M. Peter Lance T1762 T1763 T1764 T1765 T1766 T1767 T1768 xpression and Localization of Kinin Receptors in Colorectal Polyps Antoni Stadnicki, Wojciech Zclawski, Gr:cgor: Xlacl~n/k anuta Plcwka, Grazyna Nowaczyk. Urscula X'Iacmck Tadeusz Wilczok Use of NA Residues from Human Stool Io (,)uamil~' CpG-Island Hypermethylation of SR-1 in Hnnntn Colorectal Mucosa Ian T. Johnson, Nigel J. Belshaw, Gilt> O [liou I![izaI~cIh A. Williams, avid M Bradbttrn, Sarah d. Mill,. lc,hn c2~ Mathers Activin Receptor in Gastrointestinal Cancer Andreea Olaru, Florin M. Selaru, Jing Yin, Yuriko Mort, Yan Xu, Suna Wang, lena eacu, Anca Sterian, Karsten Schulmann, Joanne Young, Barbara Leggett, John M. Abraham, Stephen J. Meltzer Up-Regulation of Metalloproteinase-9 in Colorrectal Adenomas Antonio Gimeno, Alfredo Santana, Adolfo Parra-Blanco, Carlos Medina, avid Nicolas, Maria Cristina Paz-Cabrera, Begona Grosso, duardo Salido, nrique Quintero ifferences Between Proximal and istal Upper Gastrointestinal Adenocarcinomas: Proteomic Approach Suresh Sharma, ssam Sheta, Ira Goldknopf, Christopher Moskaluk, Steven Powell, Alexander Zaika, Wa'el 1-Rifai The Value of Biliary Levels of Hepatocarcinoma- Intestine-Pancreas/Pancreatitis-associated Protein I in iagnosing Biliary Malignancies Chiung-Yu Chen, Shu-Chu Shiesh evelopment of a Molecular Method and Biochemical Assay for the etection and Quantification of Intestinal Bacteria Implicated in Colon Carcinogenesis Sean. McGarr, Jason M. Ridlon, Phillip B. Hylemon An valuation of COX-2 and COX-2-ependent Gene Product xpression in Mid-Gut Carcinoid Tumours Ian S. Cadden, Brian Johnston, Graham Turner, Joy Ardill, avid Mccance, Ann McGinty The Use of Immunoelectron Microscopy in iagnosis of Gastric Neuroendocrine Tumours Reidar Fossmark, Tom C. Martinsen, Kenji Kashima, Helge L. Waldum AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Growth, evelopment and Aging PIATRIC GASTRONTROLOGY Pregnancy, Birth and arly Childhood Factors in Adult T1769 Gastro-Oesophageal Reflux isease: A Case-Control Study Imtiyaz Mohammed, Peter Nightingale, Nigel Trudgill Cimetidine, Cisapride, Both, or Neither for Infant T1770 sophagitis: Symptomatic Response to 6m Randomized, ouble Blind, Placebo-Controlled Therapy in 100 Babies Susan R. Orenstein, Theresa M. Shalaby, Sheryl F. Kelsey, ric A. Frankel someprazole Based One-Week Triple Therapy irected T1771 by Antibiogram for radication of Helicobacter pylori Infection in Children Tina Siegert, avid Amos, Matthias Kappler, Martin Alberer, Stephan Buderus, Holger Ruessmann, Sibylle Koletzko enotes W Poster of istinction P-239

46 T U S A Y MAY 18 T1772 T1773 T1774 T1775 T1776 T1777 T1778 T1779 T1780 T1781 T1782 POSTR SSSIONS--COMBIN SCINC Lansoprazole for the Treatment of Non-rosive and rosive sophagitis in Adolescents T1786 Stephen Fiedorek, Vasundhara Tolia, Bidan Huang, Julie Stolle, Chang Lee, avid Gremse osinophilic sophagitis () in Toddlers with Feeding isorder Scott Pentiuk, Claire Miller, Ajay Kaul T1787 Aerophagia in Children and Adults enesh Chitkara, Albert Bredenoord, Mu Wang, Mary J. Rucker, Nicholas J. Talley Abdominal Pain in Children: Incidence in a Population Based Birth Cohort T1788 enesh K. Chitkara, Heiko e Schepper, Mary J. Rucker, Amy L. Weaver, Slavica K. Katusic, Giles R. Locke III, Nicholas J. Talley Abdominal Pain in Children: Is the Recall Accurate? Miguel Saps, Nader N. Youssef, Galen. Switzer, Annette T1789 L. Langseder, Alvaro Cristiani, Carlo i Lorenzo Abdominal Pain: Organic vs. Non-Organic. Why oes It Matter? A Quality of Life Study Nader N. Youssef, Annette L. Langseder, Barbara J. Verga, Richard L. Mones, Joel R. Rosh T1790 Functional Constipation in Infants: A Follow-up Study M. M. van den Berg, C. H. van Rossum, Fleur de Lorijn, Marc A. Benninga Quality of Life in Childhood Constipation: A T1791 Comparison Study Nader N. Youssef, Annette L. Langseder, Barbara J. Verga, Richard L. Mones, Joel R. Rosh Overweight and Obesity, Risk Factors for Functional T1792 Constipation in Children? Sudipta Misra, Amy Lee, Kathy Gensel Graft Versus Host isease and Gastrointestinal Symptoms of Pediatric Patients After Allogeneic Bone Marrow Transplantation T1793 Yoram Bujanover, Bela Bielorai, Amos Toren, Batia Weiss Curcumin Reduces the evelopment of Necrotizing nterocolitis in Neonatal Rats Melissa. Halpern, YoIanda G. Meza, Tara A. Saunders, T1794 Sarah oelle, Catherine S. Williams, Bohuslav vorak AM-5:00 PM Hall F T1795 Sponsored by: Intestinal isorders GI INFCTIONS AN IARRHAL ISORRS Sugar Intolerance in Irritable Bowel Syndrome: The T1796 T1783 Role of Small Bowel Bacterial Overgrowth Gabriella Nucera, Andrea Lupascu, Maurizio Gabrielli, Angelo Santoliquido, Cristiano Lauritano, Luca Santarelli, Giovanni Cammarota, Giovanni Gasbarrini, Antonio Gasbarrini T 1784 Bacterial nterotoxins Stimulate Release of the Neurotransmitter [3H] Noradrenaline from Neuronally ifferentiated PC12 Cells Anna C. Casbum-Jones, Susan C. Barnett, Michael J. G. Farthing T1797 T1785 A Phase 2 Study of the Toxin Binding Polymer Tolevamer in Patients with C. difficile - Associated iarrhea Thomas Louie, Jennifer Peppe, C. Kevin Watt, avid T1798 Johnson, Rasheed A. Mohammed, Gordon ow, Karl Weiss, T1799 Stuart Simon, avid avidson Clostridium ifficile Toxoid Vaccine in Recurrent C. ifficile Associated iarrhea Stavros Sougioultzis, Lorraine Kyne, enise rudy, Sarah Keates, Seema Maroo, Charalabos Pothoulakis, Paul Giannasca, Michel Warny, Cynthia Lee, Thomas Monath, Ciaran P. Kelly ffects of nteropathogenic. coli (PC) and Citrobacter rodentium Infection on Murine Intestinal pithelial Cells Suzana. Savkovic, Michelle Muza-Moons, Jennilee Villanueva, avid Yang, Gall Hecht The Clinical Application of Polymerase Chain Reaction to iagnose Clostridium difficile in Hospitalized Patients with iarrhea Michael S. Morelli Jr., Susan. Rouster, Ralph A. Giannella, Kenneth. Sherman xploration of the Role of Bismuth Thiols in Control of Bacterial Infection Associated with Biliary Stent Occlusion Hongjun Zhang, Jevon Tang, Xiangwen Meng, Jackie Tsang, Tat-Kin Tsang Identification of ifferentially xpressed Genes Following Bacterial nterotoxin-induced Neuronal Growth and ifferentiation in PC12 Cells Anna C. Casburn-Jones, Catriona Young, Pawel Herzyk, Giorgia Riboldi-Tunnicliffe, Michael J. G. Farthing Tissue Invasive Cytomegalovirus (CMV) isease without Antigenemia in Solid Organ Transplant Recipients Jill Mcermid, Sita Gourishankar, Clarence K. W. Wong Pathogenesis of H. Pylori isease: Functional ITAM-like Proteins Bind to the Two Tandem SH2 omain of Syk and May Seriously ffect the Host Immune Response and the Syk Signaling Response Momoyo Asahi Rifalazil Prevents Relapsing of Clostridium difficile- Associated iarrhea Anton M. Pauline, ft G. Kokkotou, avid Rothstein, Ciaran P. Kelly, Charalabos Pothoulakis Tumour Necrosis Factor Alpha oes Not Appear To Be an Important Cytokine in the Immune Response to Cryptosporidium parvum in a Mouse Model of Infection Sarah Lean, Patricia Smith, Stuart Mconald, Vincent Mconald nterohepatic Helicobacter Species in Laboratory Mice May Influence the Results of Animal xperiments Ulrich R. M Bohr, Michael Selgrad, Christian Ochmann, Andreas Fenske, oerthe Kuester, Albert Roessner, Thomas Wex, Peter Malfertheiner CGRP- and SP-Mediated Mast Cell egranulation Activates RG Neurons In Vitro Frederik e Jonge, Alfons B. A. Kroese, Ann e Laet, Luc Van Nassauw, Hugh R. P. Miller, Piere-Paul Van Bogaert, Jean-Pierre Timmermans Inhibition of Na-Amino Acid co-transport in the Chronically Inflamed Rabbit Intestine Is Mediated by Arachidonic Acid Metabolites Steven Coon, Michael Baird, Sheik Wisel, John Fromkes, Urea Sundaram Absorption of Water from a Liposomal Oral Rehydration Solution (ORS): An In-vivo Perfusion Study of Rat Small Intestine Pradip K. Bardhan, Hamidur Rahman, avid A. Sack HIV Viral Protein R Induces Human Intestinal pithelial Cell ysfunction Ya-Qin Zhu, ong Liang, Yu Lu, Yuqi Zhao, Xiao-i Tan P-240 enotes W Poster of istinction

47 :~i00 ~18oo T1801 T1802 r&00 T1803 T1804,&00 T1805 POSTR SSSIONSnCOMBIN SCINC Passive Immunisation of Hamsters Against Clostridium difficile Infection Using Anti-Clostridium difficile Surface T1812 Layer Protein Antibodies Julie O'Brien, Matthew McCabe, eirdre Ni idhin, ermot Kelleher Mucosal Carboxyldextran Prevents Loss of Paracellular Barrier Function in uodenal Biopsies of Children with T1813 Chronic iarrhea and in Rat Ileum in Vitro Pieter B. Bijlsma, Amanda Kiliaan, Johanna scher, Greet Scholten, Jack Groot, Jan Taminiau An Increase in Intestinal Barrier Permeability uring Human Astrovirus Infection T1814 Lindsey A. Moser, Stacey L. Schultz-Cherry Novel vidence Suggesting Clostridium ifficile Is Actually Present in Human Gut Flora More Frequently Than Previously Suspected Shiho Konno, Masahiro lizuka, Kenji Sasaki, Akiko Sato, T1815 Yasuo Horie, Sumio Watanabe Genetic Variation in the Ileal Bile Acid Binding Protein Gene (FABP6) in Subjects with iarrhea Robert J. Pell, Natalie F. Barley, Umma Khair, Julian R.F. Wakers T1816 Whole Intestinal Permeability in Patients with Chronic iarrhea as a Non-Invasive Measure of Organic isease Shane M. evlin, Jonathon Meddings AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Intestinal isorders HOST-PATHOGN INTRACTIONS IN TH INTSTINAL TRACT T1806 T1807 T1808 T1809 T1810 T1811 PC-mediated Alterations in NH Activity Involve Translocated Intimin Receptor and Protein Kinase C (PKC) Kim Hodges, Ravinder K. Gill, Krishnamurthy Ramaswamy, Pradeep K. udeja, Gall Hecht Probiotic Lactobacillus GG Secretory Factors Ameliorate Hydrogen Peroxide-Induced isruption of Intestinal pithelial Tight Junctions Ankur Seth, Fang Yah,. Brent Polk, R. K. Rao nteropathogenic. Call (PC) Infection Inhibits Butyrate Uptake in Caco-2 cells Alip Borthakur, Kim Hodges, Ravinder K. Gill, Krishnamurthy Ramaswamy, Gall A. Hecht, Pradeep K. udeja Mechanism of Probiotic/Commensal Mediated Protection Against Invasive Salmonella Infection Liam O'Mahony, Barbara Shell, John MacSharry, Louise O'Callaghan, John K. Collins, Gerald O'Sullivan, Barry Kiely, Fergus Shanahan Oral Treatment with lactobacillus Farciminis Improves N. Brasiliensis-Induced Inflammation of Gut and Lung in Rats Helene utamene, Yann Bastien, Valerie Tondereau, Florence Lamine, Lionel Bueno, Jean Fioramonti, Vassilia Theodorou Lactobacillus Farciminis Prevents Stress-Induced Increase in Colonic Permeability and Sensitivity to istension in Rats : Role of Nitric Oxide Afifa Ait-Belgnaoui, Florence Lamine, Wei Han, Helene utamene, Jean Fioramonti, Lionel Bueno, Vassilia Theodorou T1817 T1818 Fermentable Fiber nhances the xclusion Immune Response in Piglets Infected with Salmonella Typhimurium Nancy J. Correa, Ren M. Stephen, Sharon M ono\an. 11 R. Gaskins, Kelly A. Tappenden The ffects of Probiotic Bacteria on Spontaneous Contraction of Isolated Guinea Pig Intestine Matteo Massi, Pierfranco loan, Roherta gudriesi.,\lbctto Chiarini, Beatrice Vitali, Patrizia Brigidi, Kat-en kammer, Paolo Gionchetti, Massimo Campieri The ffect of Intravenous and lntracolonic Administration of Formyl-Methionyl-Leucyl- Phenylalanine (FMLP) on Intestinal Inflammation in the Chronic Relapsed Phase of Colitis Gerardo A. Hemandez, Caroline B. Appleyard NA erived from Probiotic Bacteria Modulates Human endritic Cell Phenotype and Function Karen Lammers, Ailsa Hart, Patrizia Brigidi, Beatrice Vitali, Femando Rizzello, Paolo Gionchetti, Massimo Campieri, Michael Kamm, Stella Knight, Andrew Stagg The ffect of Fermentable Fibers on Intestinal Function and Structure Following Salmonella typhimurium Infection Renu M. Stephen, Nancy J. Correa-Matos, Sharon M. onovan Sr., Brian M. Chung, Kelly A. Tappenden Polarized Fibronectin Secretion Induced by Adenosine Regulates Bacterial-pithelial Interaction Baljit Walia, Lixin Wang, Florencia Castenada, Rahul Bajaj, Jesse Roman, idier Merlin, Andrew T. Gewirtz, Shanthi V. Sitaraman Characterization of a Murine Model of nteropathogenic. Call Infection Suzana. Savkovic, Jennilee Villanueva, Kristina A. Matkowskyj, Gall Hecht AM-5:00 PM Hall F Sponsored by: Intestinal isorders RGULATION OF TIGHT JUNCTION BARRIR FUNCTION TNF-a Modulation of Intestinal pithelial Tight T1819 Junction Barrier Requires NF-KB -ependent Myosin Light Chain Kinase (MLCK) Activation Thomas Y. Ma, ongmei Ye Inhibition of the Zonulin-ependent Increased Intestinal T1820 Permeability Prevents the Onset Of Type 1 iabetes In BB/Wor Rats Anna Sapone, Tammara Watts, ebra Counts, Ronald Zielke, Barbara Bizzarri, Alessio Fasano Transforming Growth Factor ~ nhances the nteric T1821 pithelial Barrier via Activation of RK/MAPK and SMA2/3 Signaling, and Up-regulation of the Tight Junction Protein, Claudin-1 Kathryn L. Howe, Colin R. Reardon, erek M. McKay Zeta (g) & elta (8) Isoforms of PKC Modulate T1822 Intestinal Barrier Function (BF) in Opposing irection: Molecular Modulation of Tight-Junctional Occludin All Banan, Lijuan Zhang, Maliha Shaikh, Jeremy Fields, Helieh Oz, Christopher B. Forsyth, All Keshavarzian The xpression of Claudins in Inflammatory Bowel T1823 isease Shyam Prasad, Katri Kaukinen, Roberto Mingrino, Thomas Maconald, Jane Collins enotes W Poster of istinction P-241

48 r POSTR SSSIONSmCOMBIN SCINC T, U S A Y MAY 18 T1824 T1825 T1826 T1827 T1828 T1829 T1830 T1831 T1832 T1833 T1834 T1835 T1836 Intestinal Flora Is Involved in the Physiologic Regulation of Colonic Paracellular Permeability: Role of Proteinase-Activated Receptor (PAR)-2 Nicolas Cenac, Rafael Garcia-Villar, Christel Salvador- Cartier, Jean Fioramonti, Lionel Bueno pidermal Growth Factor Attenuates Acetaldehyde- Induced Reorganization of Actin Cytoskeleton and isruption of Tight Junctions Parimal Sheth, Ankur Seth, S. Basuroy, R. K. Rao Mast Cells Induce pithelial Barrier ysfunction by Activation of Protease-Activated Receptor 2 (PAR2) ileen F. Grady, Ping-Chang Yang, Silvia Amadesi, Claire Jacob, Graeme S. Cottrell, Pare Singh, alila armoul, Mary Perdue, Nigel W. Bunnett Involvement of the Proteinase-Activated Receptor 2 (PAR-2) in the Zot/zonulin-Mediated Regulation of Intestinal Tight Junctions Maria Grazia Clemente, Stefanie N. Vogel, Morley Hollenberg, Stefano e Virgilis, Alessio Fasano Increased Intestinal Permeability (IP) in Subjects with Irritable Bowel Syndrome (IBS) Two Years After the Walkerton Outbreak of Waterborne Gastroenteritis John K. Marshall, Marroon Thabane, Jonathon Meddings, Amit Garg, William Clark, John Howard, Marina Salvadori, Stephen M. Collins NH-2 Blockade Restores Barrier Function in Ischemia- Injured Intestines Adam Moeser, Anthony Blikslager Mechanism of TNF-~x Induced Increase in Intestinal pithelial Tight Junction Permeability: Role of NF-KB Pathways Thomas Y. Ma, Michel A. Boivin, Hamid M. Said Thrombin nhances Barrier Function of the Intestinal pithelium Annette Neumann, Michael P. Manns, Michael Goeke Zonulin Is Structurally and Functionally Related to the Mucosal Mast Cells-erived Mast Cell Protease II avid Adams, ugene Fang, Stefanie M. Vogel, Alessio Fasano Time-Course of Functional and Molecular Alterations of Tight Junctions Following Acute Stress in Mice Julien emaude, Laurent Ferrier, Christel Salvador-Cartier, Jean Fioramonti, Lionel Bueno Recovery of Barrier Function in Ischemic Porcine Ileum Is Attributable to ClC-2 Chloride Channels Localized to Tight Junctions Adam Moeser, Anthony Blikslager Involvement of pithelial Cell Mysosin Light Chain Kinase in Tight Junction Colonic Permeability Increase and Rectal Allodynia Induced by LPS from.coli Raphael Moriez, Helene utamene, Christel Salvador- Cartier, Jean Fioramonti, Lionel Bueno Acute Stress-Induced Colonic Hypersensitivity is Linked to an Increase of Paracellular Permeability in Rats: Role of Myosin Light Chain Kinase Aftra Ait-Belgnaoui, Sylvie Bradesi, Vassilia Theodorou, Jean Fioramonti, Lionel Bueno AM-5:00 PM Hall F Sponsored by: Nutrition & Obesity NUTRINT TRANSPORT, SIGNALING AN GN XPRSSION Potential Mechanisms Underlying Genistein-lnduced T1837 Changes in Intestinal Cell ynamics in the Neonatal Piglet Intestine An-Chian Chen, Sharon M. onovan Regional ifferences in Adaptive Response of Intestinal T1838 Amino Acid and Peptide Transporter mrna xpression to Removal of ietary Nutrient Supply Alison Howard, Robert A. Goodlad, ianne Ford, Julian R. F. Walters, Barry H. Hirst Cloning and xpression of Three Members of the T1839 Human GAT2 Gene Family Using Saccharomyces cerevisiae as a Model System of Gene xpression Aaron Turkish, Mahajabeen Padamsee, Peter Oelkers, Annette L. Henneberry, Stephen L. Sturley The Amplitude of uodenal Pressure Waves Affects the T1840 Absorption of Short Chain Fatty Acids Itta M. Minderhoud, Andre J. P. M. Smout, Melvin Samsom C36 Contributes to Blood Clearance of Model T1841 Triglyceride-Rich Particles and Targets Them to Specific Tissues Mimi N. Ton, Nada A. Abumrad, Richard J. eckelbaum xpression of Iron Absorption Genes in Mouse Large T1842 Intestine Ken Takeuchi, Ingvar Bjarnason, Gladys O. Latunde-ada, Abas Laftah, Robert J. Simpson, Andrew T. McKie Comparative Gene Chip Analysis of 14,000 Genes in T1843 Mice eprived of ietary Phosphate Jennifer K. Uno, Hua Xu, Pawel R. Kiela, Samantha H. Serey, James F. Collins, Fayez K. Ghishan Gene xpression and Mapping of Nutrient Regulated T1844 Biological Pathways in the Human Small Intestine Freddy Troost, Robert-Jan Brummer Fish Oil and Soy lsoflavanoids Modify Cell T1845 Proliferation, Apoptosis and the xpression of strogen Receptor a and [~ in the Colonic Mucosa of the Rat lizabeth K. Lund, Franziska Kramer, Vibeke Breinholt, lan T. Johnson Butyratednduced PPAR~/xpression Is Not Associated T1846 with pithelial Cell ifferentiation Sandra Ulrich, Tanja Gaschott, Astrid Waechtershaeuser, Juergen Stein AM-5:00 PM Sponsored by: Nutrition & Obesity NUTRINTS AN GUT FUNCTION Hall F T1847 L-Glutamine Prevents Acetaldehyde-Induced isruption of Tight Junctions (TJ) by Preventing Reorganization of Actin Cytoskeleton and Changes in Phosphorylation of TJ Proteins Ankur Seth, Shyamali Basuroy, Parimal Sheth, R. K. Rao P-242 ~ enotes W Poster of istinction

49 T POSTR SSSIONSnCOMBIN SCINC T1848 T1849 T1850 T1851 T1852 T1853 T1854 T1855 T1856 ffect of the Viscosity of nteral Nutrition Solutions on Gastric mptying T1860 Yasuyuki Shimoyama, Motoyasu Kusano, Hiroaki Zai, Masaki Maeda, Tatsuya Higuchi, Sayaka Sugimoto, Masatomo Mort Glucose-Stimulated Intestinal Secretion Involves the T1861 Glucose Sensor, SGLT-3 and Release of 5-HT Samara L. Freeman, iana I. Chavez, Melissa A. Valdellon, Helen. Raybould ffects of Intraduodenal Fatty Acids on Appetite, T1862 Antropyloroduodenal Motility and Plasma CCK and GLP-I in Humans are ependent on Their Chain Length Kate L. Feltrin, Tanya J. Little, James H. Meyer, Michael Horowitz, Andre J. P. M Smout, Judith Wishart, Amelia N. Pilichiewicz, Thomas Rades, Ian M. Chapman, Christine Feinle-Bisset T1863 Intestinal Sensing of Glucose: Localization of Candidate Molecules Richard Young, Kate Sutherland, JianJun Lu, Nicole Cooper, L. Ashley Blackshaw, Michael Horowitz T1864 Intestinal Permeability Refects Allergenic Potency of ifferent Allergens in Ig Mediated Food Allergy Sabine Buehner, avid Quarcoo, Birgit Ahrens, Anke Meews, Gerald Reese, Stefan Vieths, Herbert Lochs, ckard Hamelmann Gastric Volumes in Response to Isocaloric Liquid and T1865 Mixed Meals in Healthy Humans Heiko e Schepper, Michael Camilleri, Filippo Cremonini, Amy Foxx-Orenstein, uane Burton Small Intestinal Nutrient Feedback on Gastric Motility T1866 Is Increased in the Critically I11 Marianne Chapman, Robert Fraser, Rosalie Vozzo, Laura Bryant, William Tam, Nam Nguyen, Betty Zacharakis, Ross Butler, Geoffrey avidson, Michael Horowitz TI867 The ffect of Body Mass Index on Gastrointestinal Transit: A Study in Celiac isease Riadh Sadik, Hasse Abrahamsson, Anders Kilander, Per-Ove Stotzer ffect of ating and Nutrients on Recurrent Abdominal Pain in Children: A Population-Based Study T1868 Suhaib A. Abudayyeh, Mark A. Gilger, avid Y. Graham, Kimberly J. O'malley, Linda Rabeneck, Hoda M. Malaty AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Pancreatic isorders XPRIMNTAL PANCRATITIS/PANCRATIC ACINAR AN UCTAL CLL BIOLOGY The ffects of VIP, VPAC1-R Agonist and VPAC2-R T1857 Agonist on xperimental Acute Pancreatitis Tetsuhide Ito, Mizuho Kojima, Hisato Igarashi, Takamasa Ohno, Yoshiyuki Arita, Ken Kawabe, avid H. Coy, Robert T. Jensen, Hajime Nawata Prostaglandin Formation and Bradykinin-Mediated T1858 dema Formation uring Cerulein-Induced Acute Pancreatitis in Rats Thomas Griesbacher, Rufina Schuligoi, Bernhard A. Peskar TNF-c~ Induces MAdCAM-1 on Murine Panceatic T1859 ndothelial Cells in vitro Tomoaki Arldo, Merilyn Jennings, John lrod, Paul Jordan, Takashi Job, Makoto Itoh, J. Steven Alexander T1869 T1870 T1871 T1872 T1873 T1874 Sensitization of TRPV1 Currents in a Rat Model ol Acute Pancreatitis John Winston, Wenze Wang, ttuai_~hi Yin, Philip I~aL/d~. Pankaj Pasricha Proteinase Activated Receptor (PAR)-2 ls oun Regulated in Caerulein-lnduced Pancreatitis Anupryia Sharma, Xiaohong Tao. Arun Gopal BroN<c Ligon, George Perides, Michael L. Steer Galanin Is Located in Nerves Associated with Ihe Pancreatic Vasculature and Reduces Pancrealic Va,,cular Perfusion Mark. Brooke-Smith, Colin J. Carmi, James Ioottli, Gh],, T. P. Saccone Molecular Mechanism of the Apoptosis of the Intestinal pithelial Cells in Rat Severe Acute Pancreatitis Makoto Shinzeki, Yoshifumi Takeyama, Takashi Ueda, Shinji Kishi, Takeo Yasuda, Naoki Matsumura, Hidehiro Sawa, Yoshikazu Kuroda ffects of Sirolimus on Ischemia/Reperfusion Injury of the Pancreas in Rats Frederik Serr, Heike Lauer, Barbara Armann, Temujiin ansranjavin, Christiane Kerner, Tonja Rhein, irk Uhlmann, Andrea Tannapfel, Johann Hauss, Helmut Witzigmann Intravenous Selenium in l-arginine-lnduced xperimental Acute Pancreatitis Jon G. Hardman, Conor Shields, Raymond McMahon, Paul Redmond, Ajith K. Siriwardena ifferential xpression of TLR2 and TLR4 in Rat Caerulein-Induced Pancreatitis Naoki Matsumura, Yoshifumi Takeyama, Takashi Ueda, Makoto Shinzeki, Hidehiro Sawa, Yoshikazu Kuroda Role of Hydrophobic Bile Salts, Phospholipids and Cholesterol Crystals in a Rat Model of Biliary Pancreatitis L. Paul Paul van Minnen, Niels G. Venneman, Jaap. van ijk, Hein G. Gooszen, Louis M. A. Akkermans, Karel J. van rpecum isturbed Gastrointestinal Smooth Muscle Contractility uring Acute Necrotising Pancreatitis in Mice Tom C. Seerden, Joris G. e Man, Benedicte Y. e Winter, Arnold G. Herman, Paul A. Pelckmans Platelet Function in Acute xperimental Pancreatitis Thilo Hackert, agmar Pfeil, Werner Hartwig, Martha-Maria Gebhard, Markus Buechler, Jens Wemer Lymphocyte Migration Profiles in Acute Pancreatitis Martin Bluth, ominico Viterbo, Yin-Yao Lin, Seto Chice, Victor Ocasio, mad Kandil, Cathy Mueller, Tamar Smith- Norowitz, Michael Zenilman The ffect of Tumor Necrosis Factor Receptor-p55/-p75 in Pathogenesis of Severe Acute Pancreatitis Qi Zhu, Weiyan Yao, Yaozong Yuan Hepatocyte Growth Factor Attenuates Pancreatic amages in Severe Acute Pancreatitis in Rats Jinliang Ni, Yaozong Yuan, Weiyan Yao Subtotal Colectomy oes Not Reduce Pancreatic Infection in xperimental Acute Pancreatitis L. Paul van Minnen, Vincent B. Nieuwenhuijs, Menno T. de Bruijn, Maarten R. Visser, Louis M. A. Akkermans, Hein G. Gooszen The Therapeutic ffect of OXPAPC in Animal Model of Severe Acute Pancreatitis Xing-Peng Wang, Let Li enotes W Poster of istinction P-243

50 POSTR SSSIONS--COMBIN SCINC T1875 T1876 T1877 T1878 T1879 T1880 T1881 T1882 T1883 The Protective ffect of Melatonin on L-Arginine- Induced xperimental Acute Pancreatitis in Rats Annamaria Szabolcs IV, Peter Hegyi, Ilona Varga, Jozsef Kaszaki, Gabor Papai, Tamas Letoha, Reka Sari, Zoltan Rakonczay Jr., Janos Lonovics, Russel Reiter, Tamas Takacs Internalization of GF by Migrating/Invasive Pancreatic uctular Tumor Cells Is Mediated by a ynamin- Cortactin-N-WASp Complex at orsal Ruffles/Waves James. Orth, ugene W. Krueger, Mark A. McNiven Zymogen Granule Formation and Golgi Morphology in Pancreatic Acinar Cells Are Mediated by the Large GTPase ynamin Shaun G. Weller, Sophie ahan, Mark A. McNiven GLP-1 Induced ifferentiation of Pancreatic uctal Precursor Cell Line to Insulin-producing Cells Ji un Lee, Jing Wen, Han-Soo Kim, Seung Woo Park, Jae- Bock Chung, Jin-Kyung Kang, Si Young Song TNF-(x Activates Proline-Rich Tyrosine Kinase 2 (PYK2) in Pancreatic Acinar Cells by Protein Kinase C ependent Mechanism Akihiko Satoh, Melissa S. aghighian, Joseph R. Reeve Jr., Stephen J. Pandol, Anna S. Gukovskaya Novel Protein Kinase C Isoforms ~ and Mediate Cholecystokinin-Induced Activation of PYK2 and NF-KB in Pancreatic Acinar Cells by iverging Pathways Akihiko Satoh, Anna S. Gukovskaya, Melissa S. aghighian, Joseph R. Reeve Jr., Stephen J. Pandol Cloning and xpression of the Mouse IP15 (Interferon- Inducible Portein 15), a New Gene Activated in Pancreas uring Acute Pancreatitis That Inhibits Cell Proliferation Alejandro Ropolo, aniel Grasso, Romina Pardo, Maria C. Cerquetti, Juan L. lovanna, Maria I. Vaccaro Molecular Interactions of the HSP70-Cochaperone, Cysteine String Protein, with Acinar Cell Ca2+-Signaling and Membrane Fusion Regulatory Proteins Ning Weng, iana. H. Thomas, Janice. A. Braun, Guy. Groblewski Clusterin Overexpressed in Acute Pancreatitis Protects the Acinar Cell Line AR4-2J from Apoptotic Stimuli Hans Bodeker, Vuk Savkovic, Sebastian Gaiser, Joachim Mossner, Volker Keim P-244 ~ enotes W Poster of istinction

51 POSTR SSSIONS~BASIC SCINC BASIC SCINC Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you o make them a priority as you visit the poster session. AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders CLLULAR RSPONSS TO HLICOBACTR INFCTION Helicobacter Pylori Infection Induces Intestinal W905 Metaplasia Related Gene Cdx2 in Gastric pithelial Cells via PTN-PI3K/Akt-NFKB Pathway Naoki Asano, Akira Imatani, Atsusbi Masamune, Motoki Ohyauchi, Makoto Yonechi, Shuichi Ohara, Tooru Shimosegawa H.pylori Induces a PYK2/SHP2 Complex that Modulates W906 Normal Human Gastric Mucous pithelial Cell Morphology Kathy Bacon, Rebecca Purice, Brett Sheppard, Clifford eveney, Michael Rutten Cyclooxygenase-2 Gene isruption nhances Gastric W907 Inflammation But Inhibits Gastric pithelial Proliferation Induced by H. pylori Infection Guoqing Li, Harry H. X. Xia, Minhu Chen, Jun Zhong Peng, Qing Gu, Jiantao Cui, Chi-Hin Cho, S. K. Lam, Marrie C. M. Lin, ouglas. Berg, Zhehui Feng, Robert Langenbach, H. F. Kung, Benjamin C. Y. Wong Surfactant Protein, a Collectiu in Gastric pithelial W908 Cells, Prevents Colonisation at Low Infective ose of Helicobacterfelis in Mice Wafa Khamri, Mulugeta Worku, Amy Anderson, Marjorie Walker, Howard Clark, Mark Thursz ifferential Regulation of Antimicrobial Peptides via W909 Toll-Like Receptors in Helicobacter Pylori Gastritis Jan Otte, Heike Neumann, Rainer Lebert, Andreas Bastian, Henning Schrader, Wolfgang. Schmidt, Frank Schmitz A Functional Toll-Like Receptor 4 Polymorphism W910 Increases the Risk of Gastric Cancer Georgina L Hold, Malcolm G. Smith, Wong-Ho Chow, Charles S. Rabkin, Joseph F. Fraumeni Jr., mad M. I- Omar W911 W912 W913 Presence of B7-H1 on Gastric pithelial Cells and Its Potential Role in Regulating T Cells uring Helicobacter Pylori Infection Soumita as, Giovanni Suarez, llen Beswick, avid Bland, Victor Reyes Helicobacter Pylori Infection Suppresses the xpression of Gastric Ghrelin Asish Bassi, Helina Kamarova, Lazlo Pazmany, Keith Bodger Helicobacterfelis Induces Hypergastrinaemia, CL Cell Hyperplasia and Gastric Carcinoids in Mongolian Gerbils Jean. Crabtree, Anthony H. T. Jeremy, Andrea Varro, Michelle Court, Philip A. Robinson, Michael F. ixon W914 W915 W916 W917 W918 W919 W920 W921 W922 W923 W924 Treatment with Gastrin and Hypergastrinemia nhance the Functional and Pathological Impairment Induced by Helicobacter Pylori (Hp) Infection in Mongolian Gerbils Tomasz M. Brzozowski, Peter C. Konturek, Zbigniew Sliwowski, anuta rozdowicz, Stanislaw J. Konturek, Jerzy Stachura, Agata Ptak-Belowska, Wieslaw W. Pawlik, ckhart G. Hahn Helicobacter Pylori Infection of the Human Antral Cell Line, NCI-N87, Alters xpression Levels of the Cell Matrix Proteins ystroglycan and Paxillin, Restthing in Increased Rates of Migration Jian Kang, Victoria S. Conlin, Susan Curtis, Ying Zhao, dwin Moore, Steven Pelech, Alison Buchan Regulation of Host Innate Immune Responses uring H. pylori Infection Parjeet K. Boughan, John T. George, Richard ArgenL john Atherton, Mona Bajaj-lliott Interleukin 113 Polymorphisms in the Gastroduodenal iseases in Korea Nayoung Kim, Jung Mogg Kim, Jin-Hyeok Hwang, Jin Wook Kim, ong Ho Lee, Hyun Chae Jung, In Sun Song Influence of Seven Years Omeprazole Induced Acid Inhibition on the Gastric Morphology in Patients with Chronic Gastro-sophageal Reflux isease Lars Lundell, Niilo Havu, Pekka Miettinen, Helge Myrvold, Lene Wallin, Risto Julkunen, Kristina Levander, Jan Hatlebakk, Bengt Liedman, Martha Lamm, Anders R. Malm, Anders Walan The Combination of Helicobacter Pylon Strain and TNo~ Polymorphism of the Host Increases the Risk of Peptic Ulcer isease in Children Michael Wilschanski, Yechiel Schlesinger, Berl Rudensky, Joseph Faber, Fredrick Ohnona, Serem Freier, Shira Refael, avid Halle Correlation of Gastric Mucosal Proliferation, p53 xpression and Total Tyrosine Kinases Activities in Helieobacter Pylori -- Induced Chronic Gastritis wa Malecka-Panas, Radzislaw Kordek, Justyna Kotynia xpression of Peroxisome Proliferator-Activated Receptor"/in Helicobacter pylon Infected Gastric pithelium Young Seok Cho, Ok Ran Shin, Sung Soo Kim, Jong Hyun Park, Hiun Suk Chae, Myung Gyu Choi, Sok Won Han, Chang on Lee, In Sik Chung ffect of H. Pylori Infection on IL-11~ and NA Repair Gene MGMT xpression Hui Liu, Cristina Semino-Mora, Cara Olsen, Steven Mog, Richard Peek, Andre ubois xpression of Notch Receptors and Id Proteins in Human Gastric Mucosa with H.pylori Infection Tomoaki Atsumi, Katsuaki Kato, Naohiro airaku, Kaname Uno, Shuichi Ohara, Tooru Shimosegawa Increased Multinucleated BrdU-Positive Parietal Cell in Helicobacter Heilmanniiqnfected Mouse Fundic Mucosa Masahiko Nakamura, Hidenori Matsui, Kaori Nishikawa, Shinichi Takahashi, Kanji Tsuchimoto enotes W Poster of istinction P-245

52 POSTR SSSIONSnBASIC SCINC W N S A Y MAY 19 AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders G: ACI/ION SCRTION AN RGULATION W925 8 W926 8 W927 W928 W929 W930 W931 W932 W933 W934 W935 W936 W937 W938 Molecular Basis for the Impairment of Acid Secretion by Parietal Cells in Faxll KO Mice Yasutaka Kato, Hiroshi Fukamachi, Masamitsu Suzuki, Tomohiko Aoe, Syunji Horie, Tatsuro Katsuno, Yasushi Saito, Kazuo Watanabe, Harnhiko Koseki, Hiroshi Ohno Intracellular Ca 2+ Handling Mechanisms uring uodenal Mucosal Ion Transport in Mice Hui ong, Zachary M. Sellers, Jimmy Y. C. Chow, Kim. Barrett Interleukin-18 Gene xpression and Regulation in Gastric Parietal Cells Lidong Wang, John el Valle Physiological Genomics of the Gastric Parietal Cell Nils Lambrecht, Iskandar Yakubov, George Sachs GABAR Receptor Agonists Stimulate Gastric Acid Secretion in Mice Laura Piqueras, Vicente Martinez Mechanisms of Benzimidazole Inhibition of Gastric H,K ATPase Charles L. Watson, Katalin F. Medzihradszky, John G. Forte Comparison of lectrical Properties and Ion Transport in Human sophageal Stratified Squamous pithelium and Barrett's sophagus Nelia A. Tobey, Chris M. Argote, Taylan Kav, Will Barlow, Roy C. Orlando Helicobacter Pylori Infection Prevents the Tolerance of Gastric Acid Suppressing ffect of Continuous H2 Receptor Antagonist Therapy Tomoo Fujisawa, Kyoichi Adachi, Yoshinori Komazawa, Takafumi Mihara, Tomoko Katsube, Takane Azumi, Kenji Furnta, Mohammad A.K. Rumi, Syunji Ishihara, Yuji Amano, Yoshikazu Kinoshita ffect of Acute and Chronic Salt Intake on Gastric Acid Secretion in Mongolian Gerbils Mohamed Sagar, Ireneusz T. Padol, Richard H. Hunt Genetic Polymorphism CYP2C19 and Its Relation to Pharmacokinetics and Acid-Suppression ffect of Proton Pump Inhibitors Chunyan Niu, Jinyan Luo Characterization of Gastric Acid Secretion in the Isolated Stomach of Flinders Line Rats Robert P. Bonin, Irerleusz T. Padol, Gervais Tougas, Richard H. Hunt oes lnterleukin 1 Beta Polymorphism Affect Gastric Acid Output in Chronic Gastritis Patients? In-Seok Lee, In-Sik Chung, Hak-Sung Lee, Hae-Won Han, Yu-Kyung Cho, Se-Hee Kim, Sang-Woo Kim, Myung-Gyu Choi, Jae-Kwang Kirn, Sok-Won Han, Kyu-Young Choi someprazole Provides Greater Control over Gastric Acid Secretion Than Lansoprazole uring Times When Heartburn Is Most Likely to Occur John ent, Tore Lind, mma Naucler, Kerstin Rohss Baseline ph Measurements for Patients with Suspected Signs and Symptoms of Reflux Laryngitis Joel Richter, Michael Vaezi, C. Richard Stasney, Clara Hwang, Todd Leathers, Mark Sostek, Reza Shaker W939 W940 Factors Responsible for Nocturnal Intragastric ph levation in H. pylori-positive Gastric Ulcer Patients Yasushi Funaki, Toshihiro Konagaya, Hiroshi Kaneko, Toshihiko Hayakawa, Akihito Kasahara, Akihito Iida, Hiroshi Imamura, Shinichi Kakumu Genetic Polymorphism Analysis of Cytochrome P4502C19 in Chinese Uigur and Han Population Chunyan Niu, JInyan Luo AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders G: PITHLIAL BARRIR: FUNCTION, INJURY AN RPAIR W941 W942 W943 W944 W945 W946 W947 W948 W949 Transient Receptor Potential Channel-1 (TRPC1) Regulates Capacitative Ca :+ ntry and Intestinal pithelial Cell Migration uring Restitution Jaladanki N. Rao, essy Boneva, Xin Guo, Lan Liu, Tongtong Zou, Huifang M. Zhang, Jian-Ying Wang thanol Induced Volume ecrease and Inhibition of Gap Junctional Traffic Is Mediated by Calcium Signalling in Cultured Gastric pithelial Cells Ham Mustonen, Tuula Kiviluoto, Hannu Paimela, Pauli Puolahkainen, ero Kivilaakso Gene Therapy with Serum Response Factor Accelerates Healing of xperimental sophageal Ulcers: Mechanistic Implications Jianyuan Chai, olgor Baatar, Andrzej S. Tarnawski ffect of a Specific JNK Inhibitor in Rat xperimental Gastric Injury Kazunori Harada, Yutaka Matsui, Keiichi Mitsuyama, Asuka Suzuki, Nobuo Tomiyasu, Kosuke Takaki, Yoshitaka Satoh, Brydon L. Bennett, Atsushi Toyonaga, Michio Sata CGRP-Immunoreactive Nerve Regeneration Is Partially ependent on Bone Morphogenetic Protein-4 as Well as bfgf: ffect of Lafutidine Masahiko Nakamura, Hiroshi Serizawa, Kanji Tsuchimoto IFN~/- and TNF~- Induced pithelial Barrier ysfunction Is Associated with Myosin Light Chain Kinase (MLCK) Protein Upregulation and Prevented by Sulfasalazine via an NFKB-Independent Mechanism Fengjun Wang, Yingmin Wang, Jerrold R. Turner C2-Associated Protein Contributes to Cell Membrane- Cytoskeleton Interaction and Cell Migration in Cultured Gastric pithelial Cells Ham Mustonen, Anna Lepisto, Sanna Lehtonen, ero Lehtonen, Pauli Puolakkainen, Harri Mustonen Regulation of Gastric Prostaglandin 2 Synthesis by Acid in Mice Infected with Helicobacter Pylori - Role of Vanilloid Type-1 Receptors Toshio Watanabe, Kazuhide Higuchi, Koichi Taira, Masaki Hamaguchi, Tetsuya Tanigawa, Masatsugu Shiba, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Takayuki Matsumoto, Tetsuo Arakawa Lafutidine Accelerates Rat Gastric Ulcer Healing by VGF Gene Activation Through Capsaicin-Sensitive Afferent Neurons Yasuhiro Fujiwara, Kazuhide Higuchi, Reiko Suto, Harunori Fujita, Takashi Takashima, Masaki Hamaguchi, Tetsuya Tanigawa, iji Sasaki, Kazunari Tominaga, Toshio Watanabe, Nobuhide Oshitani, Takayuki Matsumoto, Tetsuo Arakawa P enotes W Poster of istinction

53 POSTR SSSIONS~BASIC SCINC W950 W951 W952 W953 W954 W955 W956 W957 W958 W959 W960 Rebamipide Activates Genes Important for Regulating Metabolism, Signaling, Golgi and Cytoskeletal Functions, and Nitric Oxide in Gastric Mucosal Cells: Novel Mechanisms of Its Mucosal Protective and Ulcer Healing Actions Andrzej S. Tarnawski, Jianyuan Chai, Rama Pal Gene xpression Analysis in the Rat Gastric Mucosa After the lschemia-reperfusion Using by the Tissue Microdissection and High-ensity Oligonucleotide Array and the ffect of PPAR-gamma Ligands Tomohisa Takagi, Yuji Naito, Hiroshi Ichikawa, Naoya Tomatsuri, Kazuhiro Katada, Yutaka Isozaki, Masaaki Kuroda, Hisato Tsuboi, Toshimitsu Okuda, Satoshi Kokura, Norimasa Yoshida, Toshikazu Yoshikawa Altered Localization and ecreased xpression of Claudin 3, a Tight Junction Protein, in Rat sophageal Mucosa with Reflux sophagitis aisuke Asaoka, Hiroto Miwa, Akihiko Kurosawa, Akimitsu Ohkawa, Mariko Hojo, Toshifumi Ohkusa, Nobuhiro Sato, Masato Kawabe, He-Ping Chen, Kumiko Arai, Kousuke Izumi, Makiko Nagai Less Irritative Action of Wine and Japanese Sake in Rat Stomachs: A Comparative Study with Whisky and thanol Akari Nakagiri, Akiko Tanaka, Shinichi Kato, Koji Takeuchi Preconditioning Stress Prevents Cold Restraint Stress- Induced Gastric Lesions in Rats: Roles of COX-l, COX-2 and PLA2 Akiko Tanaka, Yoshiaki Kubo, Masaki Taniguchi, Koji Takeuchi Overexpression of Survivin, Cox2, VGF, GF and Its Receptor in Regenerating pithelium of Human Gastric Ulcers: New Insight into the Mechanisms of Healing Andrzej S. Tamawski, Shiun-Kwei Chiou, Woo Sung Moon, Jayashri Kidao Potential Gastroprotective ffect of a Leukotriene Receptor Blocker Montelukast in Alendronate-Induced Lesions of the Rat Stomach Mucosa Goksel Sener, Caner Kapucu, Sule Cetinel, sra Cikler, Gul Ayanoglu-ulger Cyclopamine, a Sonic Hedgehog Signal Inhibitor Promotes Intestinal Metaplastic Changes uring Gatric Ulcer Healing in Mice Yasutada Akiba, Manabu Nakashita, Ken-Ichi Katsube, Masahiko Nakamura, Hiroshi Nagata, Soichiro Miura, Jonathan. Kaunitz, Hiromasa Ishii Acceleration of Ulcer Healing by Pentadecapeptide BPC 157 in Rats. Involvement of ndogenous Prostaglandins and Gastric Secretion Wieslaw W. Pawlik, Predrag Sikiric, Tomasz M. Brzozowski, Sven Seiwerth, anuta rozdowicz, Robert Pajdo, Michal Pawlik, Stanislaw J. Konturek Molecular Crosstalk Between -Cadherin and ~2~1 Integrins inpithelial Cells Nina Ockendon, Andrea Buda, Peter ettmar, Massimo Pignatelli COX-2 xpression, Cellular Proliferation and Apoptosis in Barrett's sophagus and Post Ablation Mucosa Christopher J. Lewis, Susan Pritchard, Gordon Armstrong, Stephen. A. Attwood AM-5:00 PM Hall F Sponsored by: sophageal, Gastric and uodenal isorders UPPR GI TRACT MUCOSAL FNSS W961 g W962 W963 W964 W965 W966 W967 W968 W969 W970 W971 Atypical Lambda (k) Isoform of PKC Is A unique Mediator of F-Actin Cytoskeletal isassembly & Instability and Key in Oxidative amage to Monolayers of Intestinal Cells All Banan, Lijuan Zhang, Maliha Shaikh, Jeremy Z. Fields, Helieh Oz, Christopher B. Forsyth, All Keshavarzian i:: : : :,'-Z- istinctive Mechanism of Acid-Induced Bicarbonate i:... :~ Secretion in the Stomach: Involvement of Prostaglandio : P1 Receptor Subtype : = "-~ Masako Aoi, itaro Aihara, Masamune Hayashi, Koji : =. : ::~ Takeuchi =:=:. :~.~ i~ Involvement of Prostaglandin Receptor P3 Subtype ::,::: ;: ::~ and Prostacyclin IP Receptors in ecreased Acid :...~ Secretion in the Stomach after amage ::::::i <: ~7::~ Masato Nakashima, itaro Aihara, Masamune Hayashi, Koii = :: Takeuchi : : ~>: Roles of Cyclooxygenase-2 and Prostaglandin :~'~ ~'~ Receptors in Gastric Mucosal efense in Hclicobactc~... ':~ Pylori-lnfected Mice :: Koichi Taira, Toshio Watanahe, Tetsuya Tanigawa, Masatsugu Shiba, Kazunari Tominaga, Yasuhiro Fujiwara, Nobuhide Oshitani, Takayuki Matsumoto, Takayuki Matsumoto, Kazuhide Higuchi, Tetsuo Arakawa The Anti-Apoptosis Protein, Survivin, Is a Key Mediator of Adaptive Cytoprotection Against thanol-induced Gastric Mucosal Injury Michael K. Jones, Tomohiko Akahoshi, Shiun-Kwei Chiou, ~ndrzej S. Tarnawski, Tetsuya Tanigawa Geranylgeranylacetone nhances xpression of Cyclooxygenase-2 Through NFKB Activation in Rat Gastric Mucosal Cells Yuki Yabe, Hal Ying Fu, Yuko Tsukahara, Hiroaki Murata, Shingo Tsuji, Sunao Kawano Immunolocalization of a Na + (HCO3-)n Cotransporter in sophageal Submucosal Glands Hani N. Nakhoul, Solange M. Abdulnour-Nakhoul, Hendrik ejong, Nazih L. Nakhoul, Roy C. Orlando Inhibition of Glucosylceramide Synthase Attenuates the Formation of Acetic-Acid Induced Gastric Ulcer in Rats Manabu Nakashita, Soichiro Miura, Keita Uehara, Yasutada Akiba, Tetsu Takeuchi, Hidekazu Suzuki, Hiroshi Nagata, Hiromasa Ishii istinct Roles of Cox-1 and Cox-2 in Gastric Ischemia- Reperfusion Injuries in Mice Tetsuro Hiratsuka, Seiji Futagami, Atsushi Tatsuguchi, Nobue Ueki, Kenji Suzuki, Yoko Shinji, Masanori Kusunoki, Kei Shinoki, Hitoshi Nishigaki, Ken Wada, Kazumasa Miyake, Katya Gudis, Taku Tsukui, Choitsu Sakamoto Stimulation of Acid Secretion in amaged Stomach Under Inhibition of Nitric Oxide (NO) Production: Roles of Vagus and Capsaicin-Sensitive Sensory Neurons itaro Aihara, Yoshiaki Kubo, Hikaru Nishio, Koji Takeuchi Live Animal Ratiometric Intracellular ph Measurement in Rat uodenal pithelium Using SNARF-1 Tetsu Takeuchi, Lening Zhang, Jonathan. Kaunitz g enotes W Poster of istinction P-247

54 POSTR SSSIONSmBASIC SCINC W N S A Y MAY 19 W972 W973 W974 W975 W976 W977 W978 W979 Importance of Lipid Peroxidation, Sensory Nerves and Nitric Oxide Pathway in Gastroprotective Action of Grapefruit-Seed xtract Stanislaw J. Konturek, anuta rozdowicz, Tomasz M. Brzozowski, Slawomir Kwiecien, Michal Pawlik, Peter C. Konturek, Alexandra Szlachcic, Wieslaw W. Pawlik Mixed Intracellular ivalent Cation Signals uring Monochloramine-Induced Oxidative Injury in Gastric Glands of the Rabbit Breda M. McKay, John M. ubach, Aaron Wieland, avid I. Soybel Involvement of Angiotensin 1-7 in the Healing of xperimental Gastric Ulcer Wieslaw W. Pawlik, Ryszard Sendur, Jaroslaw Biernat, Teresa Pawlik, Rafal Obuchowicz, Tomasz Brzozowski, Stanislaw J. Konturek Gene xpression Analysis in the Rat Gastric Mucosal Cellular Response to Hypoxia-Reoxygenation Using High-ensity Oligonucleotide Array and Its Inhibition by PPAR-'y Ligands Kazuhiro Katada, Yuji Naito, Makoto Shimozawa, Nami Nakabe, Naoyuki Sakamoto, Yutaka Isozaki, Masaaki Kuroda, Tomohisa Takagi, Satoshi Kokura, Hiroshi Ichikawa, Norimasa Yoshida, Hiroshi Matsui, Toshikazu Yoshikawa TNF-alpha own-regulates TFF xpression in Gastric pithelial Cells Tadahito Shimada, Yoichiro Fujii, Ayako Koitabashi, Kumi Hosaka, Kyoko Tabei, Takashi Namatame, Masashi Yoneda, Hideyuki Hiraishi, Akira Terano nhancement of Cytoprotective Ability and Restoration in 72-ka Heat Shock Protein Gene-Transfected Rat Gastric Mucosal Cells Michiro Otaka, Tamotsu Matsuhashi, Masaru Odashima Mario Jin, Isao Wada, Yohei Horikawa, Koga Komatsu, Reina Ohba, Jinko Oyake, Natsumi Hatakeyama, Sumio Watanabe Apple xtracts Prevent Oxidative Injury to Human Gastric pithelial Cells in vitro Marco Romano, Giulia Graziani, Concett a Tuccillo, Vincenzo Fogliano Role of ndogenous Prostaglandins and Nitric Oxide in Mucosal efense of Inflamed Rat Stomach Masahiro Matsumoto, Masaki Taniguchi, Shinichi Kato, Koji Takeuchi AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology COLON CANCR: BASIC II W980 W981 W982 Bcb20verexpression Inhibits TRAIL-induced Mitochondrial Apoptosis in SW480 Human Colon Cancer Cells and Can Be Reversed by HA14-1 Robert Penington, Frank Sinicrope toposide Induced p53-dependent Gene xpression in the GI Tract: Analysis of BIRC3, a Candidate Gene Andrea avies, Penelope Ottewell, Anne McNamara, John R. Jenkins, Alastair J. M. Watson Lack of Guanylyl Cyclase C (GC-C) Affects Both Polyp Number and Apoptosis in APCMW+ Mice lizabeth Mann, Carmen R. Stroup, Ralph A. Giannella W983 isparate cpla2 and COX-2 xpression May Be Associated with Human Colon Tumorigenesis Mei ong, Anahita Rezaie, Masako Nakanishi, Kishore Guda, Prashant Nambiar, Jillian N. Marino, Malinda M. Sanders, Joel Levine, aniel W. Rosenberg AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology SOPHAGAL CANCR: BASIC W984 W985 W986 Regulation of Cell Proliferation and Apoptosis by PPAR~/Activation in Barrett's Carcinoma Cells Oliver A1-Taie, Tilmann Graf, Michael Scheurlen, Jochen Seufert SP53 sophageal Stress Protein nhances Cellular efence Mechanisms Mairi J. Hunter, Peter. Ross, Ted R. Hupp, Peter W. ettmar ual Role of TGF[3 in the Initiation and Progression of Barrett's Associated Oesophageal Adenocarcinoma Benjamin A. Onwuegbusi, Rebecca C. Fitzgerald AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology PANCRATIC CANCR: BASIC W987 W988 W989 W990 W991 W992 W993 Inhibition of Hypoxia Inducible Factor-1 Reduces Neoangiogenesis and VGF Production in Pancreatic Cancer in vivo and in vitro Peter Buchler, Martin Schneider Sr., O. Joe Hines, Markus W. Buchler, Howard A. Reber, Helmut Friess Matriptase Is a New Hypoxia Inducible Regulator of Tumor Cell Invasion and Metastasis Peter Buchler, Shereen Kelleg, Martin Schneider, Howard A. Rebel O. Joe Hines, Markus W. Buchler, Helmut Friess GA45a Is An NF-kB ependent Survival Factor for Pancreatic Cancer Cells Guenter Schneider, Andreas Weber, Ulrich Zechner, Franz Oswald, Roland M. Schmid, Susanne Liptay Mechanism for Maintenance of Tumor Reactive T-cells at a High Frequencies in Pancreatic Cancer Patients Friedrich H. Schmitz-Winnenthal, Philipp Beckhove, Christine Volk, Adrien Tempia Caliera, Bruno Schmied, Schirrmacher Volker, Markus Buchler, Kaspar Zgraggen Adrenomedullin Is Over-xpressed in Pancreatic Cancer and Stimulates Cell Growth, Migration and Invasion Vijaya Ramachandran, Thiruvengadam Arumugam, Gangyong Li, Lizhi Zhang, Craig Logsdon, iane Simeone nhanced xpression of Sigma in Pancreatic Cancer and Its Role in Cell Cycle Regulation and Apoptosis Jorg Kleeff, Ahmed Guweidhi, Nathalia Giese, Knut Ketterer, Markus W. Buchler, Murray Korc, Helmut Friess Reactive Oxygen Species Mediate Pro-survival ffects of Both xtracellular Matrix Proteins and Growth Factors in Pancreatic Cancer Cells Mouad dderkaoui, va C. Vaquero, Peggy P. Hong, Melissa S. aghighian, Stephen J. Pandol, Anna S. Gukovskaya P-248 ~ enotes W Poster of istinction

55 POSTR SSSIONS~BASIC SCINC W994 W995 W996 W997 W998 Cis-Hydroxyprolin Inhibits Proliferation of Pancreatic Carcinoma Cells and Pancreatic Stellate Cells W1007 Christoph Mueller, Stephan mmrich, Gisela Sparmann, iana Avram, Robert Jaster, Stefan Liebe, Joerg mmrich Ras Activation ue to Overexpression of rbb2 in the xocrine Pancreas Induces an Inflammatory Response W1008 but No Increased Proliferation Hana Algul Release of ic3b from Apoptotic Pancreatic Tumor Cells Induces Tolerance by Binding to Immature endritic W1009 Cells Jan Schmidt, Markus W. Buchler, Angela Marten Synergy Between Neurotensin and GF in Promoting RK Signaling and Growth of Human Pancreatic W1010 Cancer Krisztina Kisfalvi, Sushovan Guha, nrique Rozengurt 8 Proteomic Analysis of the TGF-~ Signaling Pathway in Pancreatic Carcinoma Cells Using RNA Interference to W1011 Silence Smad4 xpression Takaaki Imamura, Fumihiko Kanai, Takayuki Kawakami, Jazag Amarsanaa, Hideaki Ijichi, Yujin Hoshida, Yasuo Tanaka, Tsuneo Ikenoue, Keisuke Tateishi, Takao Kawabe, Makoto Miyagishi, Kazunari Taira, Fumio Imazeki, Osamu W1012 Yokosuka, Masao Omata AM-5:00 PM Hall F W1013 Sponsored by: Growth, evelopment and Aging CLL AN MOLCULAR BIOLOGY OF GUT GROWTH W999 W1000 Wl001 W1002 W1003 W1004 W1005 O w1014 RNA Localization and the stablishment of Cellular Polarity in the Gastric pithelium Jason C. Mills, Niklas Andersson, Christopher C. Chen, Thaddeus S. Stappenbeck, Jeffrey I. Gordon W1015 Isolation and Characterization of Potential Stem Cells from Mouse Small Intestine Christopher M. ekaney, Jose M. Rodriguez, M. C. Graul, Susan J. Hennirtg W1016 Pancreatic Islet Neogenesis in the Liver of STZ Mice Induced by Helper-ependent Adenovirns-Mediated Transfer of Neuro/Betacel ulin. -A Comparison Between Pdx-1 and Neuro Treatment- " Mineko Fujimiya, Hideto Kojima, Lawrence Chan W1017 B-Catenin-Tcf Signalling and Postnatal Intestinal pithelial Regeneration Margaret Hoper, Mark O'Connor, Mohamed 1-Tanani, W1018mr= Frederick C. Campbell nhancing Neuronal Survival After Stem Cell Transplantation in the Gut: ffects of Immunosuppression and Caspase Inhibition W1019 Maria-Adelaide Micci, Matthew Pattillo, Pankaj J. Pasricha The Cellular istribution of FXR and RXR~ xpression in eveloping Rat Ileal Mucosa Sandy T. Hwang, Keina R. Tompkins, Susan J. Henning W1020 Identification P38 Map Kinase Phosphorylation Sites Involved in CX2/3 Transcriptional Activity Sebastien Mongrain, Gerald Bernatchez, Nathalie Rivard, W1021 Claude Asselin Ribosomal Protein S3A as a 3'UTR Regulator of TNF Gene xpression Mark T. Worthington, Jared W. Pelo, Mary G. Harp Putative Intestine Specific nhancers Located in the 5' Sequence of the CX1 Gene Regulate CX1 xpression in the Intestine Wei Xu, rinn B. Rankin, ebra G. Silberg, unran Suh Identification of the Basal Promoter Region in the Human Intestinal NaPi-IIb Gene Hua Xu, Jennifer Uno, Michael Inouye, James Collins, Fayez Ghishan Gene-regulatory Activity of the Genomic Region Surrounding the Polymorphism Associated ~vith Adult-type Hypolactasia Jesper T. Troelsen, Tine G. K. Jensen, Jorgen Olsen In vivo Characterization of Temporal Control Region> of the Lactase Gene Promoter ric Sibley, Xiaoyong Cai, Charalambos Maravelia>. Yanhong Li HNF-4~ MOY1 Mutants Gll5S and R127W Arc efective in Binding and Transcriptional Coopcrativity With HNF-loe Theodore Simon, Joyce K ivine, Lora J. Staloch, Christopher W. Rowley Identification of Novel Genes with Aberrant Methylation in Hepatoma Cells Tetsuhiro Chiba, Osamu Yokosuka, Kenichi Fukai, Motohisa Tada, Yuichi Hirasawa, Fumio Imazeki, Hiromitsu Saisho Ileal Adaptation of Maltase-glucoamylase in Suckling Mice Weaned to a Chow Starch iet I3uford L. Nichols Jr., Milton Finegold, rwin. Sterchi Chromatin-Related Mechanisms of Thyroid Hormone Action in the Gut Fuad Alkhoury, Madhu S. Malo, lizabeth Fleming, Premraj Pushpakaran, Moushumi Mozumder, Richard A. Hodin Functional Studies of Two Splice Variants of the Mouse TRPV1 Gene Hong-Zhen Hu, Chunbo Wang, Craig K. Colton, Michael Zhu, Jackie. Wood The Cell Cycle Checkpoint Function of Kriippel-Like Factor 4 as Revealed by Transcriptional Profiling rika M. Whitney, Vincent W. Yang IV Promoter lements Involved in Small Intestinal Cryptand Villus-Specific Gene xpression Patterns Jorgen Olsen, Anders Stegmann, Jesper T. Troelsen Immediate arly Genes of Glucocorticoid Action on the eveloping Intestine Barbara Agbemafle, Thomas J. Oesterreicher, Chad A. Shaw, Susan J. Henning Analysis of Gene xpression Patterns in the uodenum of Iron eficient Rats James F. Collins, Christina A. Cumming, Monica Kiela, ric R. Hines, Fayez K. Ghishan Microarray-Based xpression Profiling of mbryonic Intestine from Math1 Null Mice Noah F. Shroyer, Huda Y. Zoghbi WlO06 Regulation of Cyclooxygenase-2 xpression by the Translational Silencer TIA-1 Glen C. Balch, Kristi Bemis-Standoli, R. aniel Beauchamp, an A. ixon enotes W Poster of istinction P-249

56 POSTR SSSIONSmBASIC SCINC W1022 xpression Profiling from Gastric Cancer Samples by Oligonucleotide Microarray Analysis Reveals Low egree of Intra-Tumor Variability Karolin Trautmann, Christine Steudel, ana Grossmann, aniela Aust, Gerhard hninger, Stephan Miehlke, Christian Thiede AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors W N S A Y MAY 19 AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONS/RCPTORS IN MALIGNANCY W1023 W1024 W1025 W1026 W1027 W1028 W1029 W1030 W1031 Neurotensin Stimulates Matrix Metalloproteinase-1 xpression in Human Cancer Cells Qingding Wang, Xiaofu Wang, B. Mark vers Prediction of Recurrence by Plasma Progastrin Levels in Patients with Colorectal Cancer Karim B. Muhammad, Richard Charnley, erek Manas, Colin Pritchard, Seamus B. Kelly Leptin Stimulates Human Colon Cancer Cell Proliferation in vitro but oes Not Promote Growth of HT-29 Xenografts in Nude Mice nor Intestinal Tumorigenesis in Apc min/+ Mice Thomas Aparicio, Larissa Kotelevets, Annick Tsocas, Jean- Pierre Laigneau, ric Chastre, Therese Lehy An Anti-Apoptotic Role for Gastrin in Barrett's Oesophagus Joseph C. Harris, Phil A. Clarke, Altaf Awan, Janusz Jankowski, Sue A. Watson xpression of Somatostatin Receptor Subtypes in Hepatocellular Carcinomas: An Immunohistoehemical Analysis Michael Blacker, Michael Schmitz, Sylvia Burghardt, Heiner Greten, Andreas de Weerth Overexpression of Gastrin-Releasing Peptide Receptor Promotes Neuroblastoma Cell Growth by Activation of Phosphatidylinositol 3-Kinase Pathway Jingbo Qiao, Junghee Kang, B. Mark vers, ai H. Chung Amidated and Glycine-extended Gastrin Releasing Peptide Stimulate Proliferation and Migration of a Colorectal Cancer Cell Line via the Same Receptor Oneel Patel, Chelsea umesny, Andrew Giraud, Graham Baldwin, Arthur Shulkes The CCK-2 Receptor Splice Variant Retaining Intron 4 Mediates Gastrin-lnduced Cox-20verexpression in Human Colon Cancer Cells He Huang, Jan M. Otte, Henning Schrader, Michael Hoecker, Wolfgang. Schmidt, Frank Schmitz Focal Adhesion Kinase (FAK) Activation by Gastrin- Releasing Peptide (GRP) nhances Cell Sequestration in Artificial Hepatic Sinusoids Cecile Perrault, Sarah Glover, than Sherman, Roger Tran- Son-Tay, Richard V. Benya HORMONS/RCPTORS: CLL BIOLOGY AN BIOCHMISTRY W1032 W1033 W1034 W1035 W1036 W1037 W1038 W1039 PKA-ependent Phosphorylation of GRK2 Augments VPAC2 Receptor Phosphorylation, Internalization, and Homologous esensitization in Smooth Muscle Cells Huiping Zhou, Karnam S. Murthy JAK2 and the PI 3-K in Loss of Cell-Cell Adhesion and Reorganization of Actin Cytoskeleton Induced by Gastrin in Intestinal pithelial Cells Audrey Ferrand, Aline Kowalski-Chauvel, Claudine Bertrand, Lucien Pradayrol, aniel Fourmy, Marlene ufresne, Catherine Seva ffect of Membrane Mechanics on Single Laminin- ystroglycan Bond Force in Live Myoblasts Richard Gilbert, George Gluck, Ayse rol, avid W. Shearer, Marc. Basson, Christine Ortiz Mechanisms of own-regulation of Neurokinin 1 Receptor Signaling Graeme S. Cottrell, ileen F. Grady, Nigel W. Bunnett Attenuation of Nitric Oxide Synthesis nhanced Plasma Ghrelin Levels Tatsuhiro Masaoka, Hidekazu Suzuki, Seiichirou Fukuhara, Sachiko Nomura, Yuka Abiko, Hiroshi Hosoda, Kumiko Kurabayashi, Yuriko Minegishi, Takayuki Ota, Kenji Kangawa, Hiromasa lshii 13-OxoO Is a New ndogenous PPAR-'y-Ligand in Human Colonic pithelial Cells (CCs) Reinhold Altmann, Tanja N. Spoettl, Michael Gruber, aniela Vogl, Manuela Gunckel, Lilly Weger, Werner Falk, Juergen Schoelmerich, Gerhard Rogler xtra-pancreatic Trypsin IV Cleaves and Activates Protease-Activated Receptors (PAR) 2 and 4 Graeme S. Cottrell, Sflvia Amadesi, ileen F. Grady, Nigel W. Bunnett Biological Activity of Fragments of Glycine-extended Gastrin Hong He, Phil Shehan, Kevin Barnham, Raymond S. Norton, Arthur Shulkes, Graham S. Baldwin AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors HORMONS/RCPTORS:GN XPRSSION AN RGULATION w1040 W1041 Cell-Specific xpression of Glucose-ependent Insulinotropic Polypeptide (GIP) Requires the Transcription Factor PX-1 Lisa I. Jepeal, Yoshio Fujitani, Michael O. Boylan, Cherrell N. Wilson, Christopher V. Wright, M. Michael Wolfe Serum Response Factor Is a Critical Requirement for VGF Signaling in Gastric Microvascular ndothelial Cells and VGF-induced Angiogenesis: Insight into the Mechanisms Jianyuan Chai, Michael K. Jones, Andrzej S. Tarnawski P-250 ~ enotes W Poster of istinction

57 v POSTR SSSIONSmBASIC SCINC W W1043 W1044 W1045 W1046 W1047 W1048 W1049 Substance P May Promote Intraabdominal Adhesion Formation by ecreasing Peritoneal Fibrinolytic Activity Karen L. Reed, Adam C. Gower, Arthur F. Stucchi, Kristen Steelman, Philip A. Cohen, Kristen C. Overman, Susan. Leeman, James M. Becker Spl Regulates Insulin ependent Neuronal NOS xpression Nada Bulus, Christopher Ferris Bombesin Regulates Cyclin I xpression Through Activation of the arly Growth Response Protein GR-1 ongmei Xiao, Christopher Albanese, Richard Pestell, Horst C. Weber nteroendocrine Cell xpression of a 6.4 KB Mouse CCK Gene Fragment in Transgenic Mice and Cultured Cells Linda C. Samuelson, Gina C. Bane, Cynthia S. Brunkan, Jennifer avis, Lymari Lopez-iaz, Jean M. Lay Negative Control by Insulin of Pancreatic Somatostatin mrna xpression in Rat and RIN-14b Cells Sophie Julien, Jean Laine, Jean Morisset own-regulation of Neurotensin xpression by Proteasome Inhibition Xiaofu Wang, Qingding Wang, B. Mark vers Characterization of Human Apelin Promoter and Regulation of Apelin Gene xpression Guiyun Wang, Wei Wei, lla W. nglander, George H. Greeley Jr. Characterization of Gene xpression Profile in Kupffer Cells Stimulated with IFN Alpha and Gamma Maria A. Zocco, milia Carloni, Mario Pescatori, Michele C. Santoro, nrico C. Nista, Giovanni Gasbarnni, Giuliano Ramadori, Antonio Gasbarrini W1054 W1055 W1056 W1057 W1058 W1059 W1060 Inhibition of Lumbar Splanchnic Afferent Mechanosensitivity by Galanin Benjamin. Phillis, L. Ashley Ashley Blackshaw orsal Motor Nucleus of the Vagus (MV) Melanocortin Receptor Activation Increases Gastric Motility in the Rat Maureen T. Cruz, Niaz Sahibzada, Joseph G. Verbalis, Richard A. Gillis Characterisation of the NK1 Antagonist SLV 317 in vitro and in viva Holger Sann, aniel Jasserand, Reinhard Brueckner, ania Reiche, ric Ronken, Andrew McCreary, Herman van Stuivenberg, Chris eckhout, Ulf Preuschoff Central and Peripheral Nociceptin Prevents thanol Induced Gastric Lesions in the Rat Giuseppina Morini, Giuseppe e Caro, Carlo Polidori, Maurizio Massi istribution of the Intermediate Conductance Potassium Channel in the Human Gastrointestinal Tract and orsal Root Ganglia Roxane Peddle, Inger-Sofie Selmer, lizabeth C. Colley, Mark Chen, Robert H. Riddell, Ronald H. Stead Group-I Metabotropic Glutamate Receptors Mediate Gastric Vagal Input to the Ferret Brainstem Richard Young, Nicole Cooper, L. Ashley Blackshaw Postprandial Ghrelin Release in Anorectic Patients After Weight Gain Baerbel Otto, Matthias Tschoep, Walter Heldwein, Manfred Fichter, Ulrich Cuntz AM-5:00 PM Hall F AM-5:00 PM Hall F Sponsored by: Hormones, Transmitters, Growth Factors and Their Receptors RCPTORS/TRANSMITTRS IN BRAIN-GUT AN GUT- BRAIN AXIS W1050 W1051 W1052 W1053 Gastroprotective ffect of Central and Periphe~-al Ghrelin Involves Prostaglandin, Nitric Oxide and the Activation of Vagal and Sensory Nerves Tomasz M. Brzozowski, Peter C. Konturek, Slawomir Kwiecien, Robert Pajdo, anuta rozdowicz, Michal Pawlik, Stanislaw J. Konturek, Wieslaw W. Pawlik, ckhart G. Hahn ffect of Peripherally Administered and ndogenous Orexin A on Gastric Acid Secretion, Gastric mptying and Half-Life of Orexin A Marcus hrstrom, Fredrik Levin, Rejbinder Kaur, Annette Kirchgessner, Per M. Hellstrom, rik Naslund Role of Central Melatonin and Pineal Gland in Attenuation of Gastric amage Induced by Stress Iwona Brzozowska, Peter C. Konturek, Thomas M. Brzozowski, Wladyslaw Bielanski, Krystyna Zwirska- Korczala, Stanislaw J. Konturek, Wieslaw W. Pawlik, ckhart G. Hahn Vagal Afferent Modulation of the Anterior Cingulate Cortex Activated by Colorectal istension is Mediated by Vagal A Fibers Containing GABA Jun Gao, Xiaoyin Wu, Chung Owyang, Ying Li Sponsored~by: Immunology, Microbiology & Inflammatory Bowel isorders PITHLIAL CLL-MICROBIAL INTRACTIONS IN INFLAMMATION AN IMMUNITY W W W1063 W1064 W1065 Participation of P41 " x and Small GTPase Racl in Helicobacter pylori Lipopolysaccharide-Triggered Activation of NAPH Oxidase 1 in Cultured Gastric Mucosal Cells Kazuhito Rokutan, Tsukasa Kawahara, Yuki Kuwano, Hisano MIno, Shigetada Teshima-Kondo Bacterial ffector Protein Regulates Both NF-kappaB and beta-catenin Pathways in Human Intestinal pithelia Jun Sun, Anjali S. Rao, James L. Madara Oral Administration of Probiotic Bacterial NA Ameliorates Colonic Inflammation in vivo: vidence for Suppression of pithelial Responsiveness Humberto Jijon, Jody Backer, Hugo iaz, Phil Bach, ave Thiel, Karen Madsen Commensal Bacteria licit an Integrated Response by the Innate Immune System at the Mucosal Interface of the Intestine in vivo Sue A. Keilbaugh, Romain Banchereau, Nadiya Boiko, John J. Cebra, Gary. Wu Intestinal Proteases Modulate Fluid Secretion uring Rotavirus Infection Ajay Bansal, Jose Costa, Iman Habib, rnest Tsao, Scott Hempson, rich Mackow, Stanley Zucker, Robert Shaw enotes W Poster of istinction P-251

58 POSTR SSSIONS--BASIC SCINC W N S A Y MAY 19 W1066 W1067 W1068 W1069 W1070 W1071 W1072 Attenuation of Chemokine Response to Invasive Salmonella by Lactobacilli Caithlin O'Mahony, Padraig O'Regan, John K. Collins, Liam O'Mahony, Fergus Shanahan Induction of Intestinal pithelial Cell Apoptosis by. coli K1 Strain RS218 Michelle M. Pietzak, liza Chakraborty Rotavirns ouble-stranded RNA iminishes Wound Repair in Intestinal pithelial Cells Akiko Sato, Masahiro Iizuka, Osamu Nakagomi, Manabu Suzuki, Yasuo Horie, Shiho Konno, Kenji Sasaki, Sumio Watanabe Shigella Flexneri Induces Changes in the Neurochemical Phenotype and Alters Neuronal Morphology in the Human nteric Nervous System: Role of Nitrergic and Glutamatergic Pathways mmanuel Coron, Philippe Sansonetti, ric Letessier, ric spaze, Jean-Paul Galmiche, Michel Neunlist Recognition of Gram-Positive and Gram-Negative nteric Pathogens Requires istinct TLR Heterodimers Milena Bogunovic, Huabao Xiong, Lloyd Mayer The Role of Human Beta-defensins uring Campylobacter jejuni Infection Matthias Zilbauer, Nick orrell, John George, Parjeet Boughan, Mona Bajaj-lliott Role of NAPH Oxidase 1 in Oxidative Burst Response to Toll-Like Receptor 5 Signaling in Large Intestinal pithelial Cells Kazuhito Rokutan, Yuki Kuwano, Tsukasa Kawahara, Hisano Mino, Shigetada Teshima-Kondo W1077 W1078 W1079 WI080 W1081 W1082 Imerleukino23, a Novel IL-12-1ike Cytokine with Thl Properties, is Upregulated in the Inflamed Intestinal Mucosa of Patients with IB Paul Guarino, Muhammadzeza A. Sachedina, Sharon Hoang, Margarita Mishina, Giorgos Bamias, Brian K. Reuter, Fabio Cominelli, Theresa T. Pizarro The SNP4 (G330R) Variant of the Human Interleukin-10 Receptor 1 (IL-10R1) Cytoplasmic omain Renders Ba/ F3 Cells IL-10 Insensitive Paul Grundtner, Christoph Gasche Alternative Spliced Isoform Of the IL-17 Receptor Functions as a Soluble Receptor Mitsue Shimada, Kiyotaka Kurachi, Xiubin Gu, Richard A. Hodin, Hans-Christian Reinecker Heme Oxygenase Regulates the Balance of Inflammatory Cytokines in extran Sodium Sulfate-Induced Colitis Tomohisa Takagi, Yuji Naito, Kazuhiro Katada, Yutaka isozaki, Masaaki Kuroda, Hisato Tsuboi, Toshimitsu Okuda, Satoshi Kokura, Hiroshi Ichikawa, Norimasa Yoshida, Toshikazu Yoshikawa IL-13 Is the Key ffector Cytokiue in Ulcerative Colitis That Affects pithelial Thight Junctions, Apotosis, and Restitution Frank Heller, Peter Florian, Christian Bojarski, Michael Fromm, Martin Zeitz, Ivan Fuss, Joerg. Schuhke Thiazglidenediones (TZs) Reduce Thl Mediated Intestinal Homing in Part by Preventing or Reducing Thl Chemokine Induction Katherine L. Schaefer, Koichiro Wada, Svetlana enevich, Chen Ma, Carrie Savage, Atsushi Nakajima, Lawrence J. Saubermann W1073 Human Colon pithelial Cells Secrete Proinflammatory Cytokines in Response to Intestinal Bacteria: Comparison Between Mucosal Bacteria and Probiotics Toshifumi Ohkusa, Tetsuya Nomura, Naoto Sakamoto, Satoshi Abe, Mariko Hojo, Osamu Kobayashi, Takeshi Terai, Hiroto Miwa, Tatsuo Ogihara, Nobuhiro Sato AM-5:00 PM Hail F Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB: CYTOKINS W1083 W1084 W1085 Specific Inhibition of IC by Pralnacasan Protects from T Cell-ependent Intestinal Inflammation Arvind Batra, Inka Fedke, Bianca M. Wittig, Martin Zeitz, George Ku, John Randle, Britta Siegmund HTs nhance IL-1-Mediated COX-2 xpression via a ROS-ependent Mechanism in Human Colonic Myofibroblasts John F. i Marl, Randy C. Mifflin, Jamal I. Saada, Patrick A. Adegboyega, on W. Powel[ The Roles of Membrane and Nuclear Prostaglandin Receptor in Ulcerative Colitis Hiromi Bamba, Shinichi Ota, Kenji Fujimori, Akira Kato, Hiroyuki Miyatani, Shinichi Ban, Chiaki Kawamoto, Michio Shimizu, Yukio Yoshida, Kenji Fujiwara The Flowcytometric Analysis of Glucocorticoid Induced W1074 Tumor Necrosis Factor Receptor (GITR) and TGF-~I xpression on C4 + C25 + T Cells from the Patients with Inflammatory Bowel isease (IB) Maho lkeda, Fuminao Takeshima, Noriko Nomura, Masaki Yamakawa, Masayuki Osabe, Katsuhisa Omagari, Yohei Mizuta, Kunihiko Murase, Ikuo Murata, Shigeru Kohno Cytokine Responses in ifferent Lymphoid W1075 Compartments in IL-10/ko Mice Fed Bifidobacterium Infantis Louise O'Callaghan, Barbara Shell, John MacSharry, John K. Collins, Liam O'Mahony, Fergus Shanahan SOCS-60verexpression Increases Mucosal T Cell W1076 Proliferation and nhances Sensitivity to SS Colitis Li Li, Laurens Kruidenier, Tizong Miao, Ian R. Sanderson, Ping Wang W1086 W1087 W1088 W1089 Anti-lnflammatory Protein, Adiponectin Production in the Mesenteric Adipose Tissue in Crohn's isease Katsumi Yamamoto, Tatsuya Kiyohara, Yoko Murayarna, Takashi Fujimoto, Tatsuo Katata, Shinji Tamura, Yasuhisa Shinomura Further Characterization of Cytokine Upregulation of the Oligopeptide Transporter PepTl (hpept1) in Human Caco-2fobe Cells Stephan R. Vavricka, Mark W. Musch, Laura S. Chang, Keri Kles, Ken rabik, idier Merlin, ugene B. Chang Regulation of MAdCAM-1 xpression in Murine Colonic ndothelial Cells in Vitro Tomoaki Ando, John lrod, Merilyn Jennings, Paul Jordan, Takashi Joh, Makoto Itoh, J. Steven Alexander eficiency of NK and C1 Specific Valpha24+ NK T- Cells in Crohn's isease and Ulcerative Colitis Randall H. Grose, Adrian Cummins, Fiona Thompson P enotes W Poster of istinction

59 POSTR SSSIONS--BASIC SCINC W1090 W1091 W1092 OPC-6535 Inhibits Human and Porcine Monocyte Tumor Necrosis Factor-o~ Production in Vitro and in Vivo Hisashi Nagamoto, Takashi Maeda, Shinobu Sueyoshi, Masashi Aoyama, Toshiyuki Onogawa, Goro Miyakoda, Toyoki Mort Fractalkine (FKN) Selectively Mediates T-Cell Recruitment to the Mucosal Microvasculature in Inflammatory Bowel isease (IB) Miquel Sans, Silvio anese, Brenda M. Rivera Reyes, Carol de la Motte, Gall West, Manijeh Phillips, Jeffrey A. Katz, Claudio Fiocchi In vivo Regulation of Soluble Cytokine -receptors by Infliximab and Steroids in Crohn's isease Thierry Gustot, Andre van Gossum, Charles Nicaise, ric Quertinmont, Sandrine Roland, Jacques eviere, enis Franchimont Wll01 W1102 W1103 W1104 xtended Lifespan and Long Telomeres in Fibroblasts from Older Ulcerative Colitis Patients Katherine Getliffe, Carmen Martin-Ruiz, Thomas von Zglinicki, Chuka Nwokolo C98 Glycoprotein Mediates Colonic Inflammation Torsten Kucharzik, Andreas Lugering, Xia Liu, Andrew Gewirtz, Shanthi Sitaraman, idier Merlin Adiponectin Secretion of White Adipose Tissue in Intestinal Inflammation ex vivo and Investigation of Its Proinflammatory ffects in Vitro Gisela Paul, Angela hling, Ulf Mueller-Ladner, Gerhard Rogler, Juergen Schoelmerich, Andreas Schaeffler, Hans Herfarth Paneth Cells in Crohn's isease - ffect of NO2/ CAR15 Variants Manisba Abeya, Olagunju Ogunbiyi, Satish Keshav W1093 W1094 W1095 Release of IL-10, IL-1 Receptor Antagonist, Soluble TNF-~ Receptors I and II uring Adsorptive Granulocyte and Monocyte/Macrophage Reduction Therapy of Patients with Active Ulcerative Colitis Hiroyuki Hanai, Ken Takeuchi, Takayuki Iida, Tatsuo Tanaka, Kotaro Tozawa, Fumitoshi Watanabe, Yasuhiko Maruyama, Masami Yamada, Yasushi Iwaoka, Yoshihiko Satou, Isao Matsushita, Abby Saniabadi Anti-C25 Therapy and the Role of Cytokines in Lymphocyte Steroid Resistance Tom Creed, Stephen Hearing, Caroline Crowley, Michael Norman, Colin ayan ffect of Nicotine on Cytokine and Human ~-efensin 2 (HB2) Responses in an Organ Culture Model in IB Marian C. Aldhous, Jack Satsangi Wl105 Wl106 Wl107 Uncouped enos Activity in Chronically Inflamed Human Intestinal Microvascular ndothelial Cells Contributes to Acquired Microvascular ysfunction in IB Parvaneh Rafiee, Ossama A. Hatoum, Kirkwood A. P~idmd Jr., avid G. Binion Mucosal Production of Tumor Necrosis Factor (TNF)-~ and Interleukin (IL)-I[~ Induces Sigmoid Smooth Muscle Cells to Produce Hydrogen Peroxide (H202) in Ulcerative Colitis (UC) Weibiao Cao, Claudio Fiocchi, Victor. Pricolo ifferential Neuropeptide xpression in Pediatric Patients with Crohn's isease olar Sidpra, Lee Boyer, Alison M. J. Buchan, Kevan Jacobson ~i~7 ~ :~:~i~ AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB: INFLAMMATION AN NON-IMMUN CLLS W1096 Soluble Galectin 3 Is a Strong Colonic pithelial Cell (CC) erived Fibroblast Stimulating Factor lisabeth Lippert, Werner Falk, Thilo Kaehne, Juergen Schoelmerich, Gerhard Rogler W1108 Wl109 Suppression of ndothelial Nf-kB Activation May Be a Candidate Therapeutic Target in Patients with Ulcerative Colitis Kenji Ina, Kazuo Kusugami, Tsuyoshi Nishiwaki, Ryuichi Furuta, Osamu Watanabe, Takahisa Suzuki, Takafumi Ando, Hidemi Goto The Formation of Leukocyte-Platelets Complex in Patients with Ulcerative Colitis: A Novel Marker for the isease Activity and Response to Granulocytapheresis Yuji Koike, Nagamu Inoue, Makoto Naganuma, Yuichi Morohoshi, Atsushi Sakuraba, Shigeo Yoshizawa, Haruhiko Ogata, Yasushi lwao, Noriyuki Shiobara, Katsuya Hiraishi, Hiromasa Ishii, Toshifumi Hibi W W1098 W1099 Wll00 Pro-Angiogenic Profile of the Mucosal Microenvironment in Inflammatory Bowel isease (IB) Silvio anese, Miquel Sans, Brenda M. Rivera Reyes, Gall West, Manijeh H. Phillips, Antonio Gasbarrini, Claudio Fiocchi A Role for SPARC in the xtracellular Matrix Changes in IB Ian C. Lawrance, Francis Lloyd, Warren Raye Monocytic Leukocytes Preferentially Bind to and egrade the Adhesive Hyaluronan (HA) Matrix Made by Activated Colon Mucosal Smooth Muscle Cells. Implications for the Chronic Inflammation Associated with Inflammatory Bowel isease (IB) Carol de la Motte, Huijin Rho, Judith razba, Vincent Hascall, Scott Strong The ffect of nteric Microflora Through ToU-like Receptor 5 on Colonic pithelial Cells in Ulcerative Colitis Haruhiko Ogata, Nobuhiko Kamada, Osamu Hitotsumatsu, Nagamu Inoue, Masahiro Takaishi, Yasushi Iwao, Hiromasa Ishii, Takanori Kanai, Mamoru Watanabe, Toshifumi Hibi AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders INFLAMMATION AN INNAT IMMUNITY Cld-ependent ifferential TLR xpression in W1110 Mucosal Tissues uring Oral Listeria Monowtogenes Infection Victor Arrunategui-Correa, Hyun Sil Kim MK Is a Key Regulator in TLR5-Induced ILo8 and Wl111 MIP3A Gene xpression in Non-transformed Human Colonocytes Sang Hoon Rhee, Andrew C. Keates, oin C. Kelly, Charalabos Pothoulakis The Structure of CAR15 and the Molecular Wl 112 Mechanisms of Mutations Associated with Crohn's isease Bissan A1-Lazikani, aniel J. B. Marks, Anthony W. Segal enotes W Poster of istinction P-253

60 POSTR SSSIONS--BASIC SCINC Wl113 Wl114 Toll-Like Receptor 2 (TLR2) Induces Apical Sealing of Zonula Occludens-1 (ZO-1) via Protein Kinase C (PKC) in Intestinal pithelial Monolayers lke Carlo, Guido Gerken, aniel K. Podolsky Activation and Reprogramming of Macrophages by Helicobacter hepaticus Hilda Holcombe, Issel Lira, James G. Fox, avid B. Schauer Wl127 Wl128 Toll-like Receptors on nteroendocrine Cells: Role and Function in Gut Homeostasis? Shaival ave, Shiguang Liu, Milena Bogunovic, Scott Ple W xpression of Chaperone Protein, TCP-1 Gamma, Is own Regulated on Lymphocytes of Patients with Ulcerative Colitis Gopala Kovvali, Carlos. Minacapelli, Kiron M. as Wl115 Luteolin Blocks NF-KB Signaling and Gene xpression in Intestinal pithelial Cells and endritic Cells Isolated from KB-GFP Transgenic and IL-1W Mice Joo Sung Kim, Brigitte Allard, Christian Jobin AM-5:00 PM Hall F w N S A Y MAY 19 Wll16 Wll17 Wll18 WlI19 Wl120 Wl121 Wl122 Wl123 Wl124 Wl125 Wl126 Inflammation Anergy Characteristic of Intestinal Macrophages from Normal Mucosa is Mediated by TGF- B Blockade of NF-KB Activation Lesley. Smythies, Ronald H. Clements, Meg Mostellar- Barnum, Phillip. Smith Somatostatin ffects Integrin-Mediated Neutrophil Adhesion and Cell Signaling through Specific Receptors Mimi Takami, Jung Park, Leilla Hemati The ot-efensin isulfide Array etermines Cryptdin-4 Resistance to Proteolysis uring Activation Not Peptide Bactericidal Activity Atsuo Maemoto, Xiaoqing Qu, Hiroki Tanabe, Agnes Henschen-dman, Andre J. Ouellette ffect of Oral Administration of Isoleucine, Stimulant of Innate Immunity, in IB Patients Toshifumi Ashida, Tokiyoshi Ayabe, Syuhei Inaba, Jun Sakamoto, Takahiro Itoh, Kohtaro Okamoto, Astuo Maemoto, Masami Moriyama, Michael Zasloff, Yutaka Kohgo Rebamipide Blocks ndothelial xpression of MAdCAM- 1: Implications for Inflammatory Bowel isease Therapy Tadayuki Oshima, Takashi Joh, Fumitaka Fujita, Tsuneya Wada, Shozo Togawa, Naotaka Ogasawara, Yutaka Kondo, Keisuke Itoh, Satoshi Tanida, Hiromi Kataoka, Makoto Sasaki, J. Steven Alexander, Makoto Itoh Lipopolysaccharide (LPS) Induced Leukocyte Recruitment in the Intestine: Role for a C14 Independent Pathway Chang-Wen Chen, onna-marie McCafferty Gastric Mucosal Hyperplasia via Upregulation of Gastrin Induced by Chronic Activation of Gastric Innate Immunity Toshiro Fukui, Akiyoshi Nishio, Hiroshi Kitamura, Satoko Inoue, Keiichi Kiriya, Shinya Ohashi, Hazuki Yoshizawa, Masanori Asada, Minoru Matsuura, Kimio Kawasaki, Hiroyuki Tamaki, Hiroshi Nakase, Kazuichi Okazaki, Tsutomu Chiba LFA-1 and in vivo T Cell Activation Sravanthi Kandula, Clara Abraham Cleavage Products of Kininogen Variably Induce Proinflammatory Cytokines by Fisher Rat Splenocytes Bo Liu, Fengling Li, Irma Isordia-Salas, Harlan N. Bradford, Robert W. Colman, Robin A. Pixley, R. Balfour Sartor TLR4 and TLR2-ependent Pathways Regulate the Antimicrobial Peptide ~-efensin 2 xpression in the Intestine Maria T. Abreu, Puja Vora, Adrienne Youdim, Lisa S. Thomas, Samuel Y. Tesfay, Katie Lukasek, Kathrin S. Michelsen, Akihiro Wada, Toshiya Hirayama, Moshe Arditi Reciprocal Pro-and Anti-inflammatory Molecular vents Underlie Long-Term ndotoxin Preconditioning of the Colonic Muscularis Marcus Overhaus, Betlehem A. Flynn, Sandra Toegel, Anthony J. Bauer Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders MUCOSAL INFLAMMATION AN HOST FNS Wl129 8 Wl130 Wl131 Wl132 Wl133 Wl134 Wl135 Wl136 W1137 Wl138 vidence for a Chemokine riven Positive Feedback Loop in Isolated Lymphoid Follicle Formation Keely G. Mconald, Jacquelyn Mconough, Rodney. Newberry Potential Anti-bacterial Product, Chitinase 3-like-i, Is Upregulated Under Inflammatory Condition in Mouse and Human miko Mizoguchi, Ken Sugimoto, Ramnik J. Xavier, Atsushi Mizoguchi, Albert J. T. Millis, aniel K Podolsky Matrix Metalloproteinase and pidermal Growth Factor Receptor Transactivation Mediates Substance-P Induced MAPK Activation in Normal Human Colonic pithelial Ceils Hon-Wai Koon, ezheng Zhao, Charalabos Pothoulakis xtracellular Pressure Stimulates Macrophage Phagocytosis by Inhibiting a FAK-RK Pathway Hiroe Shiratsuchi, Marc. Basson The Role of Cldl in Host efense in Intestinal Nematode Infection Waliul I. Khan, Patricia A. Blennerhassett, Yasuaki Motomura, Ashwin K. Varghese, Monica Verma-Gandhu, Rami T. 1-Sharkawy, Luc Van Kaer, Stephen M. Collins Role of xogenous and ndogenous Leptin and Ghrelin in Healing of Colonic amage in xperimantal Ulcerative Colitis Michal Pawlik, Tomasz M. Brzozowski, Slawomir Kwiecien, Peter C. Konturek, Malgorzata Zwolinska-Wcislo, Stanislaw J. Konturek, Wieslaw W. Pawlik, Jozef Bogdal Trefoil Factor 3 Increases MMP3 xpression in Intestinal pithelial Cells Jacques Van Huysse, Pieter emetter, Ine Truyen, Klaas Vandenbroucke, ebby Laukens, Lothar Steidler, Pieter Rottiers, Claude Cuvelier The Glycoprotein (gp) 96 Is Induced uring the ifferentiation of Intestinal Macrophages (IMACS) and Absent uring Mucosal Inflammation Katja Schreiter, Martin Hausmann, Ulrike Strauch, Frauke Bataille, Werner Falk, Hans Herfarth, Juergen Schoelmerich, Gerhard Rogler erangement of ndothelial Protein C Receptor and Thrombomodulin xpression in the Intestinal Mucosa of Patients with Inflammatory Bowel iseases Simone Saibeni, lena M. Faioni, Stefano Ferrero, Gessica Fontana, Umberto Gianelli, Michele Ciulla, ugenia Biguzzi, Nicoletta Cordani, Franca Franchi, Silvano Bosari, Marco Cattaneo, Maurizio Vecchi pithelial inos iminishes nterocyte Parasitism in arly C, Parvum Infection of Neonatal Piglets Jody Gookin, Jessica Alien, Sophia Chiang, Martha Armstrong P-254 enotes W Poster of istinction

61 POSTR SSSIONS~BASIC SCINC Wl139 Wl140 Wl141 NA from Commensal Intestinal Bacteria Inhibits T Cell Stimulation Via endritic Cells Ailsa Hart, Karen Lammers, Patrizia Brigidi, Beatrice Vitali, Fernando Rizzello, Paolo Gionchetti, Massimo Campieri, Michael Kamm, Stella Knight, Andrew Stagg Activation Patterns of Mucosal osinophils in the igestive Tract Under Resting and Inflammatory Conditions Alex Straumann, Jernej Kristl, Sebastien Conus, Hans Peter Spichtin, Christoph Beglinger, Hans Uwe Simon ifferential xpression of efensins and Toll-like Receptors on pithelial and Lamina Propria Leukocytes in Inflammatory Bowel isease Nobuhide Oshitani, Yoshio Jinno, Kenji Watanabe, Toshio Watanabe, Kazunari Tominaga, Shiro Nakamura, Kazuhide Higuchi, Takayuki Matsumoto, Tetsuo Arakawa AM-5:00 PM Hall F Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders PROBIOTICS IN INTSTINAL INFLAMMATION, IMMUNITY AN IB Wl142 Wl143 Wl144 Wl145 Wl146 Wl147 Wl148 Propionibacterium Freudenreichii Componemt 1.4- ihydroxy-2-naphthoic Acid (HNA) Modulates Intestinal Bacterial Flora and Attenuated SS-Induced Colitis Yoshikiyo Okada, Yoshikazu Tsuzuki, Junichi Miyazaki, Koji Matsuzaki, Ryota Hokari, Atsushi Kawaguchi, Shigeaki Nagao, Kazuro Itoh, Soichiro Miura Helminths Modulate Mucosal T Cell Responsiveness To LPS Promoting TGF[3 Production M. Nedim Ince, Tommy Setiawan, Arthur Blum, Ahmed Metwali, avid. lliott, Joel V. Weinstock Improvement of an xperimental Colitis in Rats by Treatment with Lactic Acid Bacteria Producing Superoxide ismutase Wei Han, Annick Mercenier, Sonia Pavan, Michiel Kleerebezem, Florence Lamine, Aftra Ait-Belgnaoui, Lionel Bueno, Vassilia Theodorou, Jean Fioramonti Probiotic Modulation of endritic Cells Maureen rakes, Thomas G. Blanchard, Steven J." Czinn Non-Pathogenic scherichia Coli Inhibits Signal Transduction Pathway in Intestinal pithelial Cells: A Novel Mechanism of Action Kenichi Maeda, Nagamu Inoue, Nobuhiko Kamada, Kyoung Su Hong, Haruhiko Ogata, Hiromasa Ishii, Toshifumi Hibi Bacterial iversity and Normal Anaerobic Bacterial Flora is Restored in Pouchitis Through Probiotic Therapy Tanja Kuehbacher, Stephan Ott, Toshiki Mimura, Ulf Helwig, Paolo Gionchetti, Fernando Rizzello, Massimo Campieri, Michael Kamm, Foelsch R. Ulrich, Stefan Schreiber Anti-C3-Activated T Lymphocyte-Induced Mucosal amage in Balb/c Mice is iminished by Pre-Feeding Lactobacillus SP Catherine Streutker, Mantej Bharhani, Rajka Borojevic, Pengfei Zhou, Kenneth Croitoru Wl150 Wl151 Wl152 Wl153 Wl154 Wl155 Wl156 Wl157 Wl158 The Probiotic Agent -Coli M17 Has a Healing ffect on Proximal Inflammation of the Small Bowel Samuel Adler, Harold Jacob, Rami liakim Clostridium butyricum Culture Supernatant ownregulates Toll-like receptor 4 mrna Level in Human Colonic pithelial Cells Atsushi Isono, Tatsuro Katsuno, Hidekazu Monta, Naoki Sato, Gen'ichiro Seo, Yasushi Saito, Yasuo Suzuki Probiotic. Coli Nissle 1917 (cn) Inhibits Activation and Adhesion of Peripheral T-cells to xtracellular Matrix Andreas Sturm, Klaus Rilling, Johanna Harder-d'Heureuse, aniel Baumgart, Bertram Wiedenmann, Axcl ignass NA-Microarray-Based Comparison of Cellular Responses in Polarized T84 pithelial Cells Triggered by Probiotics:. coli Nissle 1917 (cn) and Lactobacillus acidophilus PZ1041 Christoph Cichon, Corinne nders, Ulrich Solmenb,wn. hi A. Schmidt Lactobacillus casei N Inhibits Adhesion to and Invasion of Intestinal pithelial Cells by Adherent- Invasivc. Coli Isolated from Crohn's isease Patients Isabelle Ingrassia, Antony Leplingard, Arlette arfeuillc- Michaud Selective Induction of Crohn's isease (C) Lamina Propria Mononuclear Cells (LPMC) Apoptosis by Probiotics: A Potential Mechanism for Their Therapeutic ffect Miquel Sans, Nicole Pultz, Silvio anese, Claudio e Simone, Maria Grazia Cifone, Curtis J. onskey, Claudio Fiocchi. call Nissle 1917 Induces Human Beta efensin-2 by a NF-kB ependent Mechanism in CaCo-2 cells Miriam Schlee, Jan Wehkamp, Juergen Harder, Kai Wehkamp, Jens Schroeder, duard F. Stange, Klaus Fellermann Bacterial Flora in Inflammatory Bowel isease: Full- Automatic Bacterial Flora Analyzing System with Genus or Species Specific Primers Based on 16S rna Gene Sequences for the etection and Identification of Bacterial Flora in Human Feces Hiromasa Takaishi, Ryuichiro Tanaka, Koji Nomoto, Takashi Asahara, Takahiro Matsuki, Katsuyoshi Matsuoka, Nagamu Inoue, Haruhiko Ogata, Yasushi Iwao, Toshifumi Hibi High ose of Probiotics Is ffective in the Treatment of Mild Pouchitis. A Pilot Study Paolo Gionchetti, Fernando Rizzello, Claudia Morselli, Gilberto Pierangeli, Filippo Pierangeli, Rossella Romagnoli, Federica Ugolini, Silvio Laureti, Massimo Campieri AM-5:00 PM Hall F Sponsored by: Intestinal isorders INFLAMMATION AN PITHLIAL PATHOBIOLOGY Wl159 Intestinal pithelial Cell Motility and 3-imensional Morphogenesis Requires Rho Kinase Activity Ann M. Hopkins, G. Thomas Brown, A'rian A. Pineda, Brian A. Babbin, Asma Nusrat ii ;~ : ::2 ;: <5 ~ 1:7;~ Wl149 Lactobacillus Casei Induces Paneth Cell Secretion and Is Sensitive to nteric Alpha-efensins Hiroki Tanabe, Yoshinori Shirafuji, Karine Thoreux, Miguel Freitas, Raphaelle Bourdet-Sicard, Andre Ouellette enotes W Poster of istinction P-255

62 POSTR SSSIONSmBASIC SCINC W N S A Y MAY 19 Wl160 Wl161 Wl162 Wl163 Wl164 W1165 Wl166 Classical Beta 1 (~1) Isoform of PKC Is A Novel Modulator of NF-KB / I-KB-~ and Crucial To GF Protection of Cytoskeletal Assembly and Barrier Function (BF) in Intestinal Monolayers All Banan, Lijuan Zhang, Ashkan Farhadi, Jeremy Fields, Maliha Shaikh, Ali Keshavarzian lntravital Observation of C34 + Bone Marrow Cells Trafficking in Mouse Small Intestine Koji Matsuzaki, Yoshikazu Tsuzuki, Junichi Miyazaki, Yoshikiyo Okada, Ryota Hokari, Atsushi Kawaguchi, Shigeaki Nagao, Kazuro Itoh, Soichiro Miura A Chemotherapeutic Role for Intestinal Paneth Cells Christopher M. ekaney, Susan j. Henning The Role of PKC Isoforms in Hypoxia-Reoxygenation- Induced Injury to Human Intestinal pithelial Cells Barry Tepperman, Qing Chang Protective ffect of Lactulose on extran Sulfate Sodium-Induced Colonic Inflammation in Rats Gyorgy Rural, Mitsuaki Okayama, Ryoichi Tsubouchi, Shinichi Kato, Gyula Mozsik, Koji Takeuchi Butyrate Mediated Phosphorylation and Targeting of Hsp25 to Mitochondria in IC-18 Cells: Role of p38 MAP Kinase Mark J. Ropeleski Oxidative Stress isrupts Tight Junctions by Increasing the Interaction of PP2A with Occludin by a Src Kinase- ependent Mechanism Parimal Sheth, Ankur Seth, S. Basuroy, R. K. Rao Wl174 Wl175 Wl176 Wl177 Wl178 Wl179 Wl180 Role of ndogenous Prostaglandins (PGs) and Cyclooxygenase (COX) Isozymes in Healing of Indomethacin-Induced Small Intestinal Lesions in Rats Ryoko Ohno, Hikaru Nishio, Akiko Tanaka, Koji Takeuchi Aggravation by Selective Cyclooxygenase-2 Inhibitor of extran Sulfate Sodium (SS)-Induced Colonic Lesions in Rats Mitsuaki Okayama, Ryoichi Tsubouchi, Gyorgy Rumi, Shinichi Kato, Koji Takeuchi nteric Glial Cells: A Novel Regulator of Intestinal pithelial Cell Growth Michel Neunlist, Philippe Aubert, Stephanie Bonnaud, Anne Ruehl, Francois Paris, Isabelle Neveu, Philippe Naveilhan, Jean-Paul Galmiche ffect of PKC Activation on Intracellular Ca 2+ Signaling and Integrity of Intestinal pithelial Cells Barry Tepperman, Brian ouglas Soper, Qing Chang 6-Mercaptopurine and 6-Thioguanine Inhibit Release of Prostaglandin 2 and 6oketo Prostaglandin FlOL from Human Intestinal Subepithelial Myofibroblasts In Vitro Sebastian Schroll, Alexander Sarlette, Katja Felgenhauer, Michael P. Manns, Michael Goeke Mucosal Recovery from Ischemic Injury in Wildtype and COX-2 Knockout Mice Julia Tomlinson, Anthony Blikslager Glucagon-Like Peptide-2 Mediates Protective ffects in TNBS Induced Ileitis Laurie. Wallace, Gary R. Martin, avid U Sigalet Wl167 NA-78 Induces GF Receptor Transactivation, rk MAP Kinase Signaling and Cell Proliferation in Caco-2 Colonic pithelial Cells Andrew Keates, Sarah Keates, Ciaran Kelly Wl181 Magnification Chromoendoscopy Improves the Management of Intestinal Transplantation in Children Mark Holterman, Heliodora Medina, nrico Benedetti, Ronald wing, Robert Carroll Wl168 IL-10 iminishes IFN-'y and TNF-~ Induced Fas xpression On a Murine Intestinal pithelial Cell Line and ecreases Susceptibility to Fas, IFN-~/and TNF-~ Induced Apoptosis Mantej S. Bharhani, Pengfei Zhou, Rajka Borojevic, Catherine Streutker, dwin Ho, Kenneth Croitoru Wl182 Regulation of Smad7 xpression in Crohn's isease Mucosa Giovanni Monteleone, Giovanna el Vecchio Blanco, Sabrina Ballerini, Piero Vavassori, Ivan Monteleone, aniele Fina, Sergio Bernardini, Thomas T. Macdonald, Francesco Pallone Wl169 Wl170 Mixed lntracellular ivalent Cation Signals in Response to Monochloramine in Isolated Rat Colonic Crypts Robert R. Cima, John M. ubach, Breda M. McKay, Aaron M. Wieland, avid I. Soybel Impaired Keratinocyte Transglutaminase xpression as a Marker of Reduced Cell Adhesion in Ulcerative Colitis Giuseppe 'Argenio, Nicola ella Valle, Menotti Calvani, Vittorio Cosenza, Giovanni i Matteo, Piero Giorgio, Sabrina Margarucci, Orsolina Petillo, Francesco Paolo Jori, Gianfranco Peluso Wl183 Wl eoxy-Ana4-Prostaglandin J2 Inhibits Gram Negative Bacteria-Induced RLA Phosphorylation and IL-6 Gene xpression in Intestinal pithelial Cells via Peroxisome Proliferator-Activated Receptor-~/Independent Mechanisms Pedro Ruiz, Sandra C. Kim, R. Balfour Sartor, irk Hailer nhanced xpression of the Fas Pathway Inhibitor, Flip, in the Mucosa of Patients with Crohn's isease Ivan Monteleone, Luigi Pranchi, Livia Biancone, Francesco Pallone, Giovanni Monteleone Wl171 Wl172 Novel Pro-Apoptotic Actions of Carbon ioxide on Cultured Intestinal pithelial Cells Selvi Krishnan, Steven Borkan, John H. Schwartz, Satish K. Singh GLP-2 Improves Reconstitution of Intestinal pithelium Through an Induction of pithelial Cell Migration: A TGF-Beta ependent ffect Kerem Bulut, Peter Felderbauer, Nikolaus Ansorge, Frank Schmitz, Peter Hoffmann, Wolfgang. Schmidt Wl185 Wl186 Regulation of xpression of Matrix Metalloproteinases (MMP-2, MT1- MMP) and Their Tissue Inhibitor (TIMP- 2) by IL-6 in Intestinal pithelial Cells Florencia. Castaneda, Baljit Walia, Lixin Wang, Shanthi V. Sitaraman, idier Merlin Induction of Nitric Oxide in Human Colonic Fibroblasts Yingting Zhu, Michael uffey, M. Peter Lance Wl173 Induction of Small Intestinal amage by Selective Cyclooxygenase (COX)-2 Inhibitor Under eficiency of ndogenous Nitric Oxide (NO) Yujiro Hayasbi, Ryoko Ohno, Aya Yokota, Akiko Tanaka, Koji Takeuchi W1187 Bombesin Stimulates the xpression of Hepatocyte Growth Factor and COX-2 in 3T3-L1 Fibroblasts Jizhong Cheng, Yan-Shi Guo, Courmey M. Townsend Jr., Mark R. Hellmich P enotes W Poster of istinction

63 POSTR SSSIONS~BASIC SCINC Wl188 W1189 Formalin Application in the Treatment of Radiation- Induced Hemorrhagic Proctitis: A Prospective Study of 33 Patients Isabelle tienney, Pierre Bauer, Vincent de Parades, Patrick Atienza Pivotal Role for JNK MAPK in Regulation of Intestinal Barrier Integrity Linette Willemsen, Tessa Wijnhoven, Sander van eventer, Ric van Tol AM-5:00 PM Hall F Sponsored by: Motility & Nerve-Gut Interaction BRAIN-GUT AXIS Participants will be able to: Attendees will learn about peripheral nerve pathways connecting the gastrointestinal tract with the spinal cord and brain; Attendees will learn about brain pathways involved in the processing of visceral sensations and pain; Attendess will learn about receptor mechanisms in the brainstem that mediate processing of afferent and information through the brainstem to the gastrointestinal tract; Attendees will learn about changes in brain pathways that process visceral sensory information in animal models of visceral hypersensitivity and in irritable bowel syndrome patients. W Wl191 Wl192 W Wl194 Wl195 Wl196 Wl197 Systemic. coli or H. pylori Lipopolysaccharide Induces a Transcriptional Up-Regulation of nnos in the orsal Vagal Complex lsa Quintana, Carlos Hernandez, Sara Calatayud, Juan V. splugues, Maria. Barrachina ffects of Hyperglycemia on Responses to Norepinephrine (N) in Rat orsal Motor Nucleus of the Vagus Neurons (MV) Kirsteen Browning, Richard Gillis, R. Alberto Travagli Colonic Nociception via Nucleus Submedius is Modulated by Pontine Centers in the Rat va Barkova, Geoffrey K. Turnbull, John W. ownie Acute Physical and Psychological Stress and Its Influence on Autonomic Outflow to the Gut in Irritable Bowel Syndrome Charles. R. Murray, Joanna Flynn, Laura Ratcliffe, Meron R. Jacyna, Michael A. Kamm, Anton V. mmanuel Pancreatic Polypeptide (PP) Targets Selective Populations of Pancreatic-Projecting Brainstem Vagal Motoneurons Kirsteen Browning, F. Holly Coleman, R. Alberto Travagli Peripheral Urocortin 2 Suppresses Water Avoidance Stress and CRF-Induced Colonic Motor Stimulation in Rats Million Mulugeta, Paul R. Saunders, Yvette Tache Abnormal Ghrelin and Pancreatic Polypeptide Responses in Gastroparesis Kishore V. Gaddipati, Hrair P. Simonian, Karen Kresge, Siva oma, Guenther H. Boden, Henry P. Parkman Altered Reflex Control of Gastric Motility in Mice with xperimentally-induced Colitis Michael Monroe, Nate Wallace, Craig Schneider, Pamela Homby, Jeffrey Palmer Wl198 Wl199 W1200 W1201 W1202 W1203 W1204 W1205 W1206 W1207 W1208 W1209 W1210 W1211 W1212 Involvement of Peripheral Adrenergic Receptors in the Intestinal Circulatory and Metabolic Responses ue to Stimulation of Central H3 Receptors Rafal Obuchowicz, Michal Pawlik, Ryszard Sendur, Tomasz Brzozowski, Wieslaw Pawlik Leptin and CCK Interact Synergistically to Induce Gastric Relaxation: Mediation by Vagal Low-Affinity CCK-A and Leptin Receptors Yuanxu Lu, Shi-Yi Zhou, Jen Yu Wei, Chung Owyang Role of Brain-Gut Axis in Healing of Gastric Ulcers Peter C. Konturek, Tomasz Brzozowski, Grzegorz Burnat, Slawomir Kwiecien, ckhart G. Hahn, Stanislaw ]. Konturek Vago-Vagal Reflex Responses to iv Ghrelin and CCK in Rats: A Combined Uhrasonometry-ual Nerve Recording Study avid W. Adelson, Hovsep Kosoyan, ric Chlm, MulLt~Cta Million, Yvette Tache ifferent Pseudoaffective Cardio-autonomic and Colonic Response to Colorectal istension in Flinders Sensitivc Line and Flinders Resistant Line Rats Takeshi Kamiya, Lu Wang, Yu[ang Wang, Tukang Mao, John Bienenstock, Gervais Tougas Altered Colonic Barrier and Mitochondrial Function to CRH in Chronically-Stressed Rats Maria Vicario, Javier Santos, Mar Guilarte, Carmcll A!ot>o, Maria Antolin, steban Saperas, Juan R. Malagclada CNS Administered OFQ/N Affects Colonic Propulsion in OFQ/N Ligand Knockout Mice but not in ORL-1 Receptor Knockout Mice Robert Kraichely, ric Gaumnitz, Paul Bass, Miles pstein Mast Cell Activation and Afferent Sensitivity in Nippostrongylus Brasiliensis (NB) Infected Rats Kirk Hillsley, Bingman Wang, Christine Booth, Ronald H. Stead Correlation Between Acid Concentration and fmri Activity uring Heartburn in GR Patients Mark Kern, Candy Hofmann, Tanya Rittmann, Reza Shaker Biofeedback-Assisted Relaxation ecreases Rectal Tone and Increases Pain Thresholds to istention Antonia Perello, Monica Perona, mma Barthe, Cristina PuigdellivoI, Agustin Balboa, Fermin Mearin Central Neuronal Activation and Mesenteric Afferent Sensitivity uring Postoperative Ileus in the Mouse Jejunum Mario H. Mueller, imitrios Kapitoglou, Joerg Glatzle, avid Grundy, Martin Kreis xploring the Temporal Characteristics of xcitability in the Human Brain Gut Axis Using Transcranial Magnetic Stimulation Peter Paine, Shaheen Hamdy, Anthony Hobson, Satish Mistry, lizabeth Gardener, Qasim Aziz ynamic Imaging of Cortical Activity uring Temporally istinct Stages of sophageal Pain Processing Anthony R. Hobson, Paul Furlong, Qasim Aziz Modulation of ndogenous Pain Inhibition Circuits uring Visceral Stimulation Steven M. Berman, Bruce Naliboff, Brandall Suyenobu, Lin Chang, Wilbert Gordon III, Jean Stains, meran A. Mayer A Closer Look at Insular Cortex Activity uring Hindgnt Related Sensory/Motor Function Arthi Sanjeevi, Adeyemi Lawal, Mark Kern, Candy Hofmann, Reza Shaker ::i : i: 1:3. = ~ enotes W Poster of istinction P-257

64 POSTR SSSIONS--BASIC SCINC W N S A Y MAY 19 W1213 W1214 W1215 W1216 W1217 W1218 W1219 W1220 W1221 W1222 Systemic Glucagon-like Peptide-2 Signals Satiety and ifferentially Affects the Central and nteric Nervous System Laurie. Wallace, Keith A. Sharkey, Mark G. Swain, avid L. Sigalet Characterization of the Subliminal Visceral Sensory omain in IBS Patients Mark Kern, Harjot Sidhu, Candy Hofmann, Reza Shaker Abnormal Supraspinal escending Modulation of Visceral Pain.in IBS Patients with Constipation and iarrhea Clive H. Wilder-Smith, aniel Schindler ffect of Acute Stress on Visceral Sensitivity After Previous Chronic Stressful xperience Sylvie Bradesi, Ines Schwetz, James McRoberts, Gordon Ohning, Peter G. McLean, Wendy J. Winchester, Gareth A. Hicks, meran A. Mayer Cerebral Response Patternsto Perception Threshold Adapted (PTA) Rectal Stimulation Reveal Alterations in the motional Processing of Visceral Sensory Input in Patients with Irritable Bowel Syndrome (IBS) ven at the Level of Subconscious Stimuli Viola Andresen, ominik Bach, Alexander Poellinger, Chedwa Tsrouya, Annette Foerschler, Albrecht Stroh, Marco Schmidtmann, Kilian Fach, Ivo R. van der Voort, Bertram Wiedenmann, Claus Zimmer, Burghard Klapp, Hubert Moennikes ffects of TNF on Neurons of the Rat orsal Motor Nucleus of the Vagus (MV) Isabel M. Martinez de la Pena y Valenzuela, Gerlinda. Hermann, Richard C. Rogers, R. Alberto Travagli ffect of Central Corticotropin-Releasing Factor on Hepatic Circulation in Rats: A Role of CRF~ Receptor in the Brain Masashi Yoneda, Takashi Hashimoto, Tadahito Shimada, Masaya Tamano, Hideyuki Hiraishi, Kimihide Nakamura, Akira Terano A Selective CRF2 Receptor Agonist, Urocortin 2, Blunts Colorectal istention-induced Activation of Rat Inferior Splanchnic Afferents in Vitro Yuhua Wang, Mulugeta Million, Lixin Wang, Pu-Qing Yuan, James A. McRoberts, Jen Yu Wei, Yvette Tache CRF but Not Corticosterone Is Involved in the Increased Gut Paracellular Permeability of Adult Rats Previously Submitted to Neonatal Maternal eprivation Frederick Barreau, Jean Fioramonti, Lionel Bueno ffect of Neonatal Maternal Separation Stress (NMSS) on Pain Threshold and Neurochemical Responses of Colonic Mucosa and Spinal Cord to Nocioceptive Colonic Balloon istension in Adult Rats Tian-Hua Ren, Justin C. Y. Wu, avid T. W. Yew, Wai- Keung Leung, Pin-Jin Hu, Joseph J. Y. Sung AM-5:00 PM Hall F Sponsored by: Pancreatic isorders PANCRATIC CLL BIOL/GNTICS/PHYSIOI-/RCPTORS/ NUROCHM/FIBROGNSIS W1223 Phosphatidylinositide 3-Kinase Regulates Hormone- Induced Calcium Signals in Pancreatic Acinar Cells by Inhibition of ndoplasmatic Reticulum Ca2+-ATPase Lars Fischer, Anna S. Gukovskaya, Steven H. Young, Peter Buechler, Markus W. Buechler, Helmut Friess, Stephen J. Pandol W1224 W1225 W1226 W1227 W1228 W1229 W1230 W1231 W1232 W1233 W1234 W1235 W1236 W1237 A Mitotic PKA-Mediated Pathway Induces the Association of HPI? to Chromosomal Stability Regulators in Pancreatic Cancer Cells Gwen Callahan, Raul Urrutia Stimulation of ATP Release from og Pancreatic uct pithelial Cells (PC) by Bile Acids Toan. Nguyen, Thomas Sernka Pancreatic Intraepithelial Neoplasia isplays Features of Gastrointestinal Metaplasia Nijaguna B. Prasad, Andrew V. Biankin, Noriyoshi Fukushima, Anirban Maitra, Abdel G. lkahloun, Michael Goggins, Ralph H. Hruban, Steven. Leach Association of PAR-2 SNPS with Familial and Sporadic Pancreatitis Georgios I. Papachristou, Nevin Oruc, George Charlton, Ryan George, Janette Lamb, Adam Slivka, avid C. Whitcomb Protease Activated Receptor-4 (PAR-4) Polymorphism in Familial and Sporadic Chronic Pancreatitis Nevin Oruc, Georgios I. Papachristou, Janette Lamb, George Charlton, Adam Slivka, avid C. Whitcomb VAV-2 Recruits SRC-Rho-Phosphoinositide 3-Kinase Pathways uring Cholecystokinin-Stimulated Pancreatic Acinar xocytosis Kim Minil, Nozu Fumihiko, Kusama Kazushige, Awai Toshinari, Tanaka Shigeki, Tsunoda Yasuhiro, Imawari Michio Vanilloid Receptor-1 xpressed in Pancreatic Islet Beta Cells Modifies Insulin Secretion in Rats Yasutada Akiba, Shinichi Kato, Ken-Ichi Katsube, Masahiko Nakamura, Koji Takeuchi, Hiromasa Ishii The Protein Tyrosine Phosphatase SHP2 in Pancreatic Acini: Activation by Growth Factors and Their Cellular Mechanisms of Activation Jose A. Tapia, Robert T. Jensen Gastric mptying isturbances Correlate with Pancreatic xocrine ysfunction in Patients with Long- Standing iabetes Mellitus Jutta Keller, Sebastian Brneckel, Axel Gresens, Christine Jahr, Christiane Fibbe, Peter Layer ffects of camp on Carbachol Stimulated Zymogen Activation, Secretion, and Cell Injury Anamika M. Chaudhuri, Thomas R. Kolodecik, Fred S. Gorelick Mathematical Modeling of Bicarbonate Conductance- isrupting CFTR Mutations in Pancreatic uct Cells Predict Inhibition of Pancreatic Fluid Secretion avid C. Whitcomb, G. B. rmentrout A Novel Approach for Real-time Time Measurement of Pancreas Chloride Output in vivo: The ifferential ffect of Cholecystokinin (CCK) and Secretin Tamer Coskun, Joseph R. Reeve Jr., Gary M. Green, Marshall H. Montrose III Luminal Leptin Stimulates Pancreatic nzyme Secretion in Rats Katarzyna Nawrot-Porabka, Jolanta Jaworek, Anna Leja- Szpak, Joanna Bonior, Michalina Kot, Magdalena Palonek, Joanna Szklarczyk, Zygmunt Warzecha, Artur embinski, Stanislaw Konturek, Wieslaw Pawlik Zymogen Activation in a Reconstituted Pancreatic Acinar System dwin C. Thrower, Fred S. Gorelick P-258 ~ enotes W Poster of istinction

65 POSTR SSSIONS--BASIC SCINC W W1239 W1240 W1241 W1242 W1243 Inhibition of c-jun N-terminal Kinase Attenuated the Activation of Rat Pancreatic Stellate Cells Kazuhiro Kikuta, Atsushi Masamune, Masahiro Satoh, Noriaki Suzuki, Tooru Shimosegawa Protease-activated Receptor-2 in Rat Pancreatic Stellate Cells Atsushi Masamune, Kazuhiro Kikuta, Noriaki Suzuki, Masahiro Satoh, Tooru Shimosegawa Microarray Profiling of Pancreatic Gene xpression in thanol Fed Rats: own-regulation of Protective Genes May Underlie the Sensitizing ffect of Alcohol to Pancreatitis Ilya Gukovsky, Constanze Kubisch, Aurelia Lugea, Hidekazu Tsukamoto, Stephen J. Pandol, Craig. Logsdon Activation of JAK-STAT Pathway by Platelet-derived Growth Factor-BB in Rat Pancreatic Stellate Cells Atsushi Masamune, Kazuhiro Kikuta, Masahiro Satoh, Tooru Shimosegawa Angiotensin II Is an Autocrine Stimulator of NA Synthesis in Rat Pancreatic Stellate Cells Kouji Hama, Hirohide Ohnishi, Kentaro Sugano Pancreatic Stellate Cells Inhibit Spontaneous Lymphocyte Apoptosis by IL-15 Gisela Sparmann, Peter Brock, Robert Jaster, Stefan Liebe, Joerg mmrich enotes W Poster of istinction P-259

66 POSTR SSSIONS--CLINICAL SCINC II CLINICAL SCINC W N S A Y MAY 19 Authors are required to be present during the Poster Session from 12:00-2:00 pm. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a prio~ity as you visit the poster session. AM-5:00 PM Hall F L-- _ Sponsored by: AGA; Liver and Biliary LIVR AN BILIARY CARCINOMA: MANAGMNT The Role of Long Acting Octreotide in Treating Patients W1244 with Advanced Hepatocellular Cancer (HCC). A Randomized Placebo-Controlled Trial imitris imitroulopoulos, imitris Xinopoulos, Klisthenis Tsamakidis, Athanassios Zisimopoulos, fthimios Andriotis, imosthenis Panagiotakos, Aikaterini Fotopoulou, Christina Chrysochoou, Athanassios Bazinis, Sofia Markidou, mmanouel Paraskevas Radio-frequency Ablation for Patients with W1245 Hepatocellular Carcinoma: Comparison with Percutaneous thanol Injection Shinichiro Nakamura, Yoshiyuki Kobayashi, Nobuyuki Tosbikuni, Hironori Tanaka, iji Matsumoto, Hideki Ohnishi, Kohsaku Sakaguchi, Kazuhiro Nouso, Yasushi Shiratori Combined Tamoxifen and Retinoids Affect Intratumoral W1246 Apoptosis Rate in a Rat HCC Model Marion Ganslmayer, Matthias Ocker, Gabi Kraemer, ckhart Hahn, etlef Schuppan, Christoph Herold The Study of Risk Factors of HCC and Recurrent HCC W1247 iji Matsumoto, Yoshiyuki Kobayashi, Nobuyuki Toshikuni, Shinichiro Nakamura, Hironori Tanaka, Yasuhiro Miyake, Hideki Ohnishi, Yasuyuki Araki, Mitsubiko Kawaguchi, Tosbiya Osawa, Hiroshi Ikeda, Kunihiro Shiraga, Toshihiko Kaneyoshi, Kenji Miyoshi, Kazuhiro Nouso, Kohsaku Sakaguchi, Yasusbi Shiratori The Histone-eacetylase Inhibitor SAHA Potentiates W1248 Pro-Apoptotic ffects of 5-Fluorouracil and Irinotecan in Hepatoma Cells Marion Ganslmayer, Matthias Ocker, Abdull Alajati, Steffen Zopf, ckhart G. Hahn, etlef Schuppan, Christoph Herold Percutaneous Radiofrequency Ablation for Unresectable W1249 Liver Metastases of Colorectal Cancer Yukihiro Koike, Haruhiko Yoshida, Shuichiro Shiina, Hajime Kunimata, Koji Yamashita, Yuji Kondo, Osamu Togawa, Motoko Seto, Megumi Inobe, Atsuo Yamada, Takafumi Sugimoto, Takako Ae, Tateo Kawase, Masao Omata Survival and Recurrence Rates After Complete W1250 Radiofrequency Ablation for Hepatocellular Carcinoma; Value of Lens Culinaris Agglutinin-Reactive Alphafetoprotein (AFP-L3 Fraction) Ogawa Chikara, Kudo Masatoshi, Minami Yasunori, Chung Hobyung, Kawasaki Toshihiko W1251 W1252 Antitumor ffect of OK432-Contained Polyurethane Membrane As a rug elivery System on Adenocarcinoma in Mice Seok Jeong, on Haeng Lee, Jung I1 Lee, Jin-Woo Lee, Kye Sook Kwon, Pum-Soo Kim, Hyung Gil Kim, Yong Woon Shin, a Yeon Jung, In Suh Park, Young Soo Kim 5-FU and IFN Alpha8 Combination Treatment Induce More Severe Apoptosis and Caspase Activities Than 5- FU and IFN Alpha2 Treatment in Hepatoma Cell Lines Kazuko Koike, Akinobu Takaki, Masashi Tatsukawa, Yoshiaki lwasaki, Yasushi Shiratori AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary TRATMNT OF OTHR LIVR ISASS AN COMPLICATIONS Methylprednisolone Inhibits Low Flow Hypoxia-Induced W1253 Mitochondrial ysfunction in Rat Liver Satoru Motoyama, Satoshi Saito, Yoshihiro Minamiya, Jun- Ichi Ogawa Pitavastatin Ameliorates Severe Hepatic Steatosis in W1254 Aromatase-deficient (Ar-/-) Mice Masafumi Ono, Tetsu gawa, Masaya Takahashi, Kousei Masuda, Naoaki Akisawa, Shinji Iwasaki, Toshiji Saibara, Saburo Onishi Hepatic Hemangiomas: Possible Association with Female W1255 Sex Hormones Haim Shirin, Orit Shevah, Mona Boaz, Yona Avni, Vyara Glinkova A Paradigm Shift Towards Bloodless Liver Surgery: W1256 Radiofrequency Assisted Liver Resection Optimises Safety and Minimises Blood Loss and ICU Admission Nagy A. Habib, Guiseppe Navarra, rnesto Basaglia, Long R. Jiao, Andrew V. Thillainayagam Acute Myopathy Associated with Liver Cirrhosis ; W1257 Hepatic Myopathy Ok-Jae Lee, Tae-Hyo Kim Utility of Liver Biopsy in Bone Marrow Transplant W1258 Patients Prabhleen Chahal, Cynthia Levy, Mark Litzow, Keith. Lindor Liver Cirrhosis in Sickle Cell isease W1259 Mohammad. Hoque, Tammy Naab, Behzad Kalaghchi, uane T. Smoot, Alpha T. Banks, Gordeuk Victor, Oswald Castro Utility of the ML Score for Predicting Outcomes W1260 Following Cholecystectomy in Patients with Cirrhosis Linda Perkins, Mark Jeffries, Tushar Patel P enotes W Poster of istinction

67 POSTR SSSIONSmCLINICAL SCINC AM-5:00 Sponsored by: Clinical Practice OUTCOMS RSARCH W1261 W1262 W1263 W1264 W1265 W1266 W1267 W1268 W1269 W W1271 W Hall F ietary Intake and Gastroesophageal Reflux isease: A Cross-Sectional Study in Volunteers Hashem B. l-scrag, Jessie Satia-Abouta, Linda Rabeneck Obesity Correlate with Gastroesophageal Reflux Symptoms in US Veteran Population Vikas Khurana, Rim Khurana, Prasanna Isaac, aniel L. Halberg, Sudhir Unni, Charhon Fort Symptom Severity, Quality of Life (QoL), and Psychological istress in Patients with rosive sophagitis () vs. Nonerosive sophageal isorders (N): Are They Really Similar? Borko Nojkov, Michael J. Shaw, Susan Adlis, William. Chey Psychological Profile and QOL in Patients with Functional Heartburn Sheila Rodriguez-Stanley, Maggie Wolff, All Siddiqui, Howard M. Proskin, Philip B. Miner Jr. The Impact of Baseline Scores on a Relevant Change and a Minimal Important ifference (MI) in Patient- Reported Outcomes (PROS) in Reflux isease? Ingela Wiklund, Ola Junghard Interpreting the Clinical Relevance of Treatment ifferences in Patient-Reported Outcomes (PROs) in Patients Treated for Reflux isease Ola Junghard, Ingela Wiklund Cost of Illness in a Cohort of Patients with Gastroesophageal Reflux isease Over 2 Years Michael Kulig, Marc Nocon, Andreas Leodoher, Michael Vieth, aniel Jaspersen, Joachim Labenz, Tore Lind, Wolfgang Meye~-Sabellek, Manfred Stoke, Peter Malfertheiner, Stefan N. Willich ffect of someprazole on Sleep Quality in Patients with GR: Patient-Reported Outcomes from a Randomized Controlled Trial Using the Pittsburgh Sleep Quality Index (PSQI) Questionnaire avid Johnson, William Orr, Cheryl Marple, Assunta Cuccia, Barry Traxler, Kurt Brown, Thomas Roth Is the iagnosis of Barrett's Worse Than the isease? Joel H. Rubenstein, John M. Inadomi Helicobacter Pylori-Associated Ulcer Bleeding: Should We Test for radication after Treatment? Heiko Pohl, Samuel R. G. Finlayson, Amnon Sonnenberg, ouglas J. Robertson High ose Oral Proton Pump Inhibition ecrease Re- Bleeding in High-Risk Patients with Acute Peptic Ulcer Bleeding: A Meta-Analysis Marc Bardou, Youssef Toubouti, Myriam Martel, lham Rahme, Alan Barkun The Influence of PPI ose on Treatment fficacy for Ulcer Bleeding Following ndoscopic Hemostatic Therapy (HT): A Sub-Group Analysis from the Cochrane Collaboration (CC) Systematic Review Gngoris I. Leontiadis, Linda McIntyre, Virender K. Sharrna, Colin W. Howden W1273 W1274 W1275 W1276 W1277 W1278 W1279 W1280 W1281 W1282 W1283 W1284 W1285 CYP2C19 Polymorphism and Proton Pump Inhibitors (PPI) in Helicobacter pylori radication Therapy - A Metaanalysis Gerhard G. Treiber, Matthias Schwab, Ulrich Klotz oes the fficacy of PPI Treatment for Ulcer Bleeding epend on the Nature of Pre-Randomization ndoscopic Stigmata? A Past Hoc Analysis from the Cochrane Collaboration (CC) Systematic Review Grigoris I. Leontiadis, Linda McIntyre, Virender K. Sharma, Colin W. Howden Is There a Threshold PPI ose That ecreases Non Lethal Outcomes in Patients with Non Variceal Upper GI Bleeding? Alan Barkun, Myriam Martel, Youssef Toubouti, lham Rahme, Joyce Strazzulla, Manon Petit Maintenance of Improvement in Quality of Life imensions and Symptom Control Following Initial Treatment of Upper GI Symptoms with someprazole Versus Placebo in Patients on Long-Term NSAI Therapy Nicholas J. Talley, Christopher J. Hawkey, Neville Yeomans, James M. Scheiman, Joseph Sung, Roger Jones, Goran Langstrom, Jorgen Naesdal Utilization of Antisecretory Medication in 100,000 Nova Scotia Seniors' Pharmacare Beneficiaries Between 1998 and 2002: A Cohort atabase Analysis Jordan T. Zacny, Ingrid Sketris, Chris Skedgel, George Kephart, Sander J. O. Veldhuyzen Van Zanten An vidence-based Analysis of someprazole Therapy Versus Placebo for the Prevention of Gastric or uodenal Ulcers in At-Risk Continuous NSAI Users Neville Yeomans, James M. Scheiman, Christopher J. Hawkey, Nicholas J. Talley, Nimish Vakil, Jorgen Naesdal, Goran Langstrom Methodologic Quality of Trials Affects stimates of Treatment fficacy in Functional (Non-Ulcer) yspepsia: A Meta-Analysis Based on Two Methodologic Criteria Scores Neena S. Abraham, Paul Moayyedi, Sander J. O. van Zanten Medical iagnoses in Functional yspepsia Patients Olafur S. Palsson, William. Whitehead, Victoria. Barghout, Marsha J. Turner Systematic Review and conomic valuation of Helicobacter Pylori radication Treatment for Non- Ulcer yspepsia Comfort Osonnaya, Kingsley Osonnaya, Ian R. Sanderson, Paul Swain The Quality of Published Health conomic Analyses in igestive iseases: A Systematic Review and Quantitative Appraisal Brennan M. R. Spiegel, Laura. Targownik, Vincent erosa, Gareth S. ulai, Ian M. Gralnek, Chiun-Fang Chiou Medication Taking Behavior in A Gastrointestinal Clinic: A isconnect Between Patient Behavior and Physician Knowledge Sunanda V. Kane, James ang Gastric lectrical Stimulation--A Ten Year xperience Anand P. Curuchi, Amar A1-Juburi, Babajide Familoni, Hani Rashed, Kevin Blanchard, Anti Minocha, Thomas L. Abell Outcome of Laparoscopic versus Laparotomic Cholecystectomy: A Population-Based Mortality Cohort Study avide Festi, Amanda Vestito, Antonio Colecchia, Maria P. Fantini, Marco Bosso, Massimo Clo, anilo Fusco, Carlo A. Perucci m ~ enotes W Poster of istinction P-261

68 POSTR SSSIONS--CLINICAL SCINC W N S A Y MAY 19 W1286 W1287 W1288 W1289 W1290 W1291 W1292 W1293 Long Term Followup of Trigger Point Injection for Abdominal Wall Pain Jose Nazareno, Terry Ponich, Jarnie Gregor How o US Gastroenterologists iagnose Irritable Bowel Syndrome? Brian Mulhall, Brooks. Cash, Philip Schoenfeld, William. Chey Constipation Is Often Undiagnosed or Misdiagnosed in Outpatient Clinics: iagnosis of Constipation Is Associated with Better Outcomes Olafur S. Palsson, William. Whitehead, Rona L. Levy, Andrew. Feld, Michael Von Korff, slie H. ennis, Victoria. Barghout, Marsha J. Turner Randomized Comparison of Audio Tape Recorded nhanced sophagogastric Cancer Consultations Michael Stephens, Sarah Pellard, Carolyn Gent, Rhiannon ay-thompson, Guy Blackshaw, Paul dwards, Wyn Lewis Validation of Noninvasive isease Activity Indices for Ulcerative Colitis in U.S. Patients Peter. R. Higgins, John Mapili, Marc Schwartz, Sheryl Korsnes, llen M. Zimmermann Perceived Role of Scientific vidence in the ecision to Continue Use of Complementary Therapies by Canadians with Inflammatory Bowel isease Laura C. Vanderheyden, Maria J. Verhoef, Robert J. Hilsden conomic Burden of Acute iverticular Hemorrhage in The U.S.: A Nationwide stimate Sapna Thomas, Richard C. K. Wong, Ananya as iverticular Bleeding: Long Term Outcome and Risk Factors for Recurrence Stephanie L. Jun, James. Allison, Irene Tekawa, Maqdooda Merchant, N. Marcus Thygeson, Nell Stollman W1301 W1302 W1303 iabetes Mellitus Is a Risk Factor for Colon Cancer: A Case Control Study Vikas Khurana, Rambabu Chalasani, Tejinder Singh, aniel L. Halberg, Charhon Fort Natural History of Patients with Liver Cirrhosis in Sweden uring the Last ecade Anna Gunnarsdottir, Magnus Simren, Gustav Smith, Rolf Olsson, inar Bjornsson Aggressive Local Ablation Therapy May Be ffective in Retaining Tumor Stage of Hepatocellular Carcinoma within Milan Criteria Noriyo Yamashiki, Ryosuke Tateishi, Shuichiro Shiina, Haruhiko Yoshida, Takurna Teratani, Takashi Ishikawa, Shuntaro Obt, Shinpei Sato, Tomonori Fujishirna, Miho Kanda, Yuji Kondo, Norio Mine, Takao Kawabe, Masao Omata AM-5:00 PM Hall F ~,~ Sponsored by: sophageal, Gastric and uodenal isorders NSAIS: CLINICAL STUIS Incidence of Gastroduodenal Ulcers in Patients with W1304 Arthritis and Previous Ulcer Bleeding After 6 Months of Celecoxib or iclofenac Plus Omeprazole: A Randomized, ouble-blind Study Francis K. L. Chan, Lawrence C. T. Hung, Bing Y. Suen, Vincent W. S. Wong, Aric J. Hui, Justin C. Y. Wu, Wai K. Leung, Y. T. Lee, Ka F. To, Sydney Chung, Joseph J. Y. Sung W1294 W1295 strogen-progesterone Therapy in Gastrointestinal Angiodysplasia: A Systematic Review of Controlled Clinical Trials Terence L. Angtuaco, Sandeep Khurana, Robert P. Svoboda, Colin W. Howden Predictors of Gastrointestinal Bleeding in Patients Receiving Thrombolytic Therapies for Acute ST- levation Myocardial Infarction Rahul A. Shimpi, Jeffrey Griffin, Christopher B. Granger, Robert M. Califf, Frans J. J. Van de Werf, R. J. Simes, Andrew J. Muir Maintained Symptom Control with someprazole W1305 Following Initial Treatment of Upper GI Symptoms of Patients on NSAIs Including COX-2-Selective NSAIs Christopher J. Hawkey, Neville Yeomans, James M. Scheirnan, Nicholas J. Talley, Joseph Sung, Roger Jones, Jorgen Naesdal, Goran Langstrom Gastrointestinal Prevention Strategies with ither Cox-2 W1306 Inhibitors or Generic and Non-Generic Proton Pum Inhibitors Plus NSAIs Are qually Cost-ffective in Patients with Risk Factors Angel Lanas W1296 W1297 W1298 W1299 Assessment of Patient Perception of Bowel Preparation Quality at Colonoscopy Gavin Harewood, Curtis Wright, Todd Baron Conjoint Analysis (CA) of Patient Preferences for Colorectal Cancer (CRC) Screening Strategies John K. Marshall, eborah Marshall, Reed Johnson, Kathryn Phillips, Lehana Thabane, Gary Foster, Bernie O'Brien oes Published ata Support Recent Multi-Society Colon Polyp Surveillance Guidelines? A Systematic Review of the vidence Sameer Saini, Philip Schoenfeld Barriers to Compliance with Screening Colonoscopy Among Hispanics and Non Hispanic Whites Murtaza Parekh, Antonio Serna IV, Michael Urbano, Yasser Shaib, Tahir Qaseem igestive Risk of NSAIs Assessed by French GPs: W1307 Results of a National Survey in 1777 GPs Liard Francois, Goupille Philippe Sr., Rozenberg Sylvie, Hassani Zahir, Bruley des Varannes Stanislas Sr., Bruley des Varannes Stanislas Sr. Gastrointestinal Safety and Anti-Inflammatory Activity W1308 of HCT-1026, NO-Releasing Flurbiprofen, in Healthy Humans Volunteers Stefano Fiorucci, Luca Santucci, Andrea Mencarelli, Alberto Fransioni, leonora istrutti, Piero el Soldato, Antonio Morelli W1309 Upper Gastrointestinal Bleeding and the Use of Nonsteroidal Anti-inflammatory rugs in Hemophiliacs Shonda M. Asaad, Barbara Kroner, Sylvia Cohn, James Goedert, laine yster, Hemophilia Cohort Study Group/ Muhicenter W1300 Outcomes of Follow-up Colon xamination Among a Population-Based Cohort of Colorectal Cancer Patients Stephen J. Rulyak, Margaret T. Mandelson, avid A. Lieberman, Andrew. Feld, J. T. Ylvisaker, dward H. Wagner W1310 The Comparative Healing of Gastric Ulcers with someprazole Versus Ranitidine in Patients Taking ither Continuous COX-2 Selective NSAIs or Nonselective NSAIs Jay L. Goldstein, John Johanson, Christopher J. Hawkey, Lisa Suchower, ouglas Levine P-262 ~ enotes W Poster of istinction

69 POSTR SSSIONS--CLINICAL SCINC W1311 W1312 W1313 W1314 W1315 W1316 Overall Control Of NSAI-Induced yspepsia with the Proton Pump Inhibitor (PP1) Pantoprazole: A Placebo Controlled Trial on the Onset of Symptom Relief Gerald Holtmann, Hans J. Ulmer, Christo van Rensburg, Jonas Valantinas, George Nicola, Peter Top, Wilhelm Wurst, Thomas Schwan radication of Helicobacter pylori oes Not Prevent Peptic Ulcers in Patients with Long-term Treatment with NSAIs: A Randomized, ouble Blind Placebo Controlled Trial Helena T. J. I. de Leest, Kirsti S. S. Steen, Willem F. Lems, Mart A. F. J. van de Laar, Anne-Margriet Huisman, Harry H. M. L. Houben, Piet J. Kostense, rnst J. Kuipers, Maarten Boers, Ben A. C. ijkmans Prevalence of Troublesome yspeptic Symptoms, Symptomatic and Silent Ulcers in Patients Treated with NSAIs: A Prospective Study in Primary Care Margrit Hollenz, Manfred Stoke, Joachim Labenz rradication of Helicobacter Pylori Prevents the Appearance of Peptic Ulcer in Patients Treated with NSAI. A Meta Analysis Mercedes Vergara, Javier P. Gisbert, Xavier Calvet ndoscopic Characteristics and H. Pylori Infection in NSAIs-Induced Gastric Ulcer Tomoari Kamada, Ken Haruma, Hiroaki Kusunoki, Kuniaki Sugiu, Hideki Koga, Masaharu Takeda, Jiro Hata, Keisuke Honda, Yoshinori Fujimura, Soichiro Kido, Hiroshige Hamada U.S. Adults Often Use Over-the-Counter (OTC) Analgesics Inappropriately and Without Safety Concerns Byron Cryer, George Triadafilopoulos, Charles M. Wilcox AM-5:00 PM Hall F ~ ~.. Sponsored by: sophageal, Gastric and uodenal isorders NSAIS: W1317 W1318 W1319 W1320 MCHANISMS OF INJURY AN RPAIR Survivin, an Anti-Apoptosis Protein, Is a Major Target for NSAIs-lnduced Gastric Mucosal Injury Shiun-Kwei Chiou, Michael K. Jones, Andrzej S. Tarnawski Microsomal Prostaglandin Synthase (mpgs) -1 Regulates Hepatocyte Growth Factor (HGF) Release in Gastric Fibroblasts Stimulated with Interluekin(IL)- 1beta Yoko Shinji, Taku Tsukui, Atsushi Tatsuguchi, Choitsu Sakamoto Lipoxin A4 is Protective in Gastric Mucosal Ischemia- Reperfusion (I-R) amage in Rats Nadia Sawka, Karlheinz hrlich, Bernhard A. Peskar, Brigitta M. Peskar Selective Inhibition of COX-l, but Not COX-2, Produces amage to the Gastric Mucosa of Portal Hypertensive Rats Without Affecting Normal Gastric Mucosa: Mechanistic Considerations Tomohiko Akahoshi, Tetsuya Tanigawa, Andrzej S. Tamawski, Shiun-Kwei Chiou, Makoto Hashizume, Yoshihiko Maehara, Michael K. Jones W1321 W1322 W1323 W1324 W1325 W1326 W1327 W1328 W1329 W1330 W1331 W1332 W1333 Gastrointestinal and Cardiovascular Safety of HCT- 3012, NO-Naproxen, in Aspirin-Treated Arthritic Rats. vidence That NO Compensates for COX-1 and COX-2 Inhibition Stefano Fiorucci, Anna Rita i Lorenzo, leonora istrutti, Piero el Soldato, Antonio Morelli, Giuseppe Cirino luduction of Claudin-4 and Other Tight Junction Related Proteins by NSAIS in Cultured Gastric Cells Shinji Mima, Tohru Mizushima Activation of PPARgamma and Modulation of the xpression of PPARgamma Target Genes by NSAIs in Gastric pithelial Cells Tadahito Shimada, Yoichiro Fujii, Ayako Koitabashi, Kumi Hosaka, Kyoko Tabei, Takashi Namatame, Ma~ashi Yoneda, Hideyuki Hiraishi, Akira Terano Nitric Oxide Induced by Aspirin Mediates Leukocyte Recruitment Within Mesenteric Venules lsa Quintana, Carlos Hernandez, Sara Calatayud, Juan V. splugues, Maria. Barrachina Identification of the TPO1 in Yeast and Its Possible Human Homologue, Tetran, Which Cause Phenotype Resistant to NSAIS Hyun-Jung Hwang, Tohru Mizushima ifferential ffects of Selective or Non-selective Inhibitors of Nitric Oxide Synthase on the xpression and Activity of Cyclooxygenase-2 uring Gastric Ulcer Healing Guo Jin Sheng, Wang Ji Yao, Cho Chi Hin, Koo M. Wing Leung ffect of H. Pylori radication on evelopment of Gastric and uodenal Ulcers (GU) in NSAI Users: A Meta-analysis Chang-Cheng Wang, Yubong Yuan, Richard H. Hunt ]~nfluence of Zaprinast (Type V Phosphodiesterase Inhibitor) on the NSAI-Induced xperimental nteropathy Jose M. steban-carretero, Juan-Manuel M. Herrerias Sr., Juan-Manuel M. Herrerias Jr., Pflar steban-elgado, Juan C. steban-carretero NO Releasing Aspirin (ASA) Fails to Impair Ulcer Healing in iabetic Rats due to the Reversal of the Fall in Ghrelin, Leptin and COX-2 xpression Peter C. Konturek, Tomasz Brzozowski, Vitalyy Kukharskyy, Karolina Bazela, Robert Pajdo, Wieslaw W. Pawlik, ckhart G. Hahn, Stanislaw J. Konturek Cross-Talk Between Inducible Nitric Oxide Synthase and Cyclooxygenase-2 in the Gastric Mucosa of in vivo Rat ndotoxemia Model Kaname Uno, Katsuaki Kato, Naohiro airaku, Shuichi Ohara, Yoshihito Iuchi, Junichi Fujii, Tooru Shimosegawa, Tetsuhiko Yoshimura NSAIS Induce Apoptosis Through ndoplasmic Reticulum Stress Response Shinji Tsutsumi, Tohru Mizushima ffect of Vitamin C-Releasing Aspirin on Gastric Mucosal amage Before and After H. Pylori radication Therapy Peter C. Konturek, Joanna Kania, ckhart G. Hahn, Jan W. Konturek examethasone Produces amage in the Stomach but not Small Intestine Under Inhibition of Cyclooxygenase (COX)-I Aya Yokota, Akiko Tanaka, Yoshiaki Kubo, Koji Takeuchi 7--- enotes W Poster of istinction P-263

70 i W N S A Y MAY 19 w1334 W1335 w1336 W1337 W1338 Factors Involved in Up-Regulation of inos xpression in Rat Small Intestine Following Administration of NSAIs K@ Takeuchi, Aya Yokota, Yujiro Hayashi, Katsuhide Yoshii, Akiko Tanaka Aspirin Induced Gastric Mucosal Cell eath: vidence Supporting an Apoptotic Mechanism Jacinda J. Power, Miranda S. ennis, Maria J. Redlak, Thomas A. Miller Nitric Oxide (NO)-releasing Aspirin Counteracts the Aggravation of Stress-induced Gastric Lesions by Aspirin or Coxib in iabetic Rats Tomasz M. Brzozowski, Peter C. Konturek, Pajdo Robert, Stanislaw J. Konturek, Slawomir Kwiecien, Wieslaw W. Pawlik, ckhart G. Hahn Gastrointestinal Toxicity and Tolerability of COX-2 Selective Inhibitors: A Metaanalysis Jerry McGrath, Richmond Sy., James Gregor NSAI-nteropathy with Normal Mucosal Prostaglandins Christoph M. Hotz-Behofsits, Matthew J. Walley, Gudmundur Sigthorsson, Robert Simpson, Ingvar T. Bjarnason AM-5:00 Sponsored by: Gastrointestinal Oncology SOPHAGAL CANCR: CLINICAL W1339 W1340 W1341 W1342 W1343 W1344 W1345 POSTR SSSIONS--CLINICAL SCINC Hall F oes Adjuvant Chemotherapy (CT) to Combined Chemotherapy and Radiation Therapy (RT) Improve the Outcome in Patients with Locally Advanced sophageal Cancer? Frederic di Fiore, Stephane Lecleire, Jacques Jacob, Sok Hun Seng, Brigitte Vie, Bernard Paillot, Pierre Michel ndoscopic sophageal Mucosal Resection (MR) of arly sophageal Cancer and High Grade ysplasia Canard Jean Marc, Antoine de Leusse, Palazzo Laurent, Jian Raymond, Cellier Christophe Improved Classification Largely Accounts for the Recent Increase in Gastroesophageal Junction Carcinoma Incidence ouglas Corley, Ai Kubo Self-xpanding Metal Stems in the Palliation of Malignant ysphagia: Outcome Analysis in 100 Consecutive Patients avid lphick, Beverley Smith, Julie Bagshaw, Stuart Riley FG-PT as a Staging Method for sophageal Cancer Burkhard H. A. von Rahden, Hubert J. Stein, Hinrich Wieder, Wo/fgang A. Weber, Katja Ott, Mario Sarbia, J. Ruediger Siewert The ffects of someprazole Combined with Aspirin or Rofecoxib on Steady State Prostaglandin 2 Production in Patients with Barrett's sophagus George Triadafilopoulos, Baljeet Kaur, Barry Traxler, Ngoc Chu, ouglas Levine, Alan Weston Aspirin Versus Coxibs for Chemoprevention in Barrett's sophagus Chin Hur, Norman S. Nishioka, Lee Simon, G. Scott Gazelle w1346 w1347 w1348 w1349 W1350 w1351 w1352 w1353 w1354 w1355 The Clinical fficacy of Intensive Chemoradiation for Inoperable Squamous sophageal Cancer: Case-control Study Simon K. H Wong, S. F. Leung, Angus C. W. Chan, nders K. W. Ng, Sydney S. C. Chung The Cyclooxygenase-2 Inhibitors Rofecoxib and Celecoxib Protect Against sophageal Carcinoma Marc Bardou, Alan N. Barkun, Joumana Ghosn, Marie Hudson, lbam Rahme Cholecystectomy, Complications of Gastroesophageal Reflux isease and the Risk of Adenocarcinomas of the sophagus and Cardia dward A. Lew, Monir Hossain, Raj K. Goyal, J. Michael Gaziano High xpousure to Polycyclic Aromatic Hydrocarbons May Contribute to High Risk of sophageal Cancer in Northeastern Iran Farin Kamangar, Paul Strickland, Akram Pourshams, Reza Malekzadeb, Paolo Bofl-etta, Mark Roth, Christian Abnet, Mitra Sadaatian-lahi, Nasser Rakhshani, Paul Brennan, Arash temadi, Sanford awsey Histopathologic valuation of arly sophageal Adenocarcinoma; Implications for ndoscopic Versus Surgical Therapy M. Westerterp, L. B. Koppert, Christianne Buskens, Herman van ekken, Fiebo Ten Kate, Hugo Tilanus, J. J. B. van Lansehot Association Between Breast Cancer (BC) and sophageal Adenocarcinoma (AC) In Women Sapna Thomas, Amitabh Chak, Gregory S. Cooper, Ananya as Trend in Age Conditional Risk of eveloping Invasive sophageal Cancer (PC)in the 1990s Sapna Thomas, Amitabh Chak, Gregory S. Cooper, Ananya as ndoscopy Policy and Risk of Missing Upper Gastrointestinal Malignancy in Patients Aged over 55 Years - ata from the Scottish Audit of Gastric and Oesophageal Cancer (SAGOC) Perminder S. Phull, mma Shaft, Ken Park, Tracey Rapson Rise of sophageal Adenocarcinoma in USA Is Temporally Associated with the Rise in Carbonated Soft rink Consumption Mohandas K. Mallath ffect of Rofecoxib on Cyclooxygenase-2 xpression, Prostaglandin 2 Content, and Cell Proliferation in Barrett's sophagus dward Lung, Young S. Kim, James Gum, Jason. Morrow, ouglas Corley AM-5:00 PM Hall F,~(~! "~l.r " Sponsored by: Gastrointestinal Oncology GASTRIC CANCR: CLINICAL II Results at 6 Years of a Follow-up Programme for the W1356 valuation of the Risk of Neoplastic Lesions in Patients with Atrophic Body Gastritis (ABG) Bruno Annibale, dith Lahner, Giancarlo 'Ambra, Gabriele Capurso, milio i Giulio, Massimo Milione, Cesare Bordi, Gianfranco elle Fave P enotes W Poster of istinction

71 POSTR SSSIONS~CLINICAL SCINC W1357 W1358 W1359 The Relative Importance of the ifferent Sites of Gastric Biopsies in etection of Intestinal Metaplasia in Clinical Practice Shaji Sebastian, oin Feeny, Ramona McLoughlin, Paul Crotty, Humphrey O'Connor, Martin Buckley, Colm O'Morain What Is the Appropriate ndoscopic Surveillance Interval for Patients with Helicobacter PyloN-Associated Gastritis and Intestinal Metaplasia in a Country with Moderate Risk of Gastric Cancer? Andrea Rajnakova, Khek-Yu Ho, Min Tun, Khay Guan Yeoh Chromoendoscopic valuation of Intestinal Metaplasia: An Update Leonardo M. Manabat Jr., Jane R. Campos, rnesto O. omingo, Felix M. Zano, Jose Carnate, Leonardo B. Manabat Sr. AM-5:00 PM Hall F Mortal Convention Center Sponsored by: Gastrointestinal Oncology LYMPHOMAS Interobserver Variation in the Histopathologic W1360 Assessment of MALT/MALT Lymphoma: Towards a Consensus Hala l-zimaity, Andrew Wotherspoon, Henry Appelman, Christiane Copie-Bergman, Michael ixon, aphne de Jong, Antoine de Mascarel, Joel Greenson, Peter Isaacson, H. K. Muller-Hermelink, Hiroyoshi Ota, Massimo Ruggae, Antonella Savio, Manfred Stolte, mina Torlakovic, Mamoun gounes Capsule ndoscopy in Gasric Malt Lymphoma and W1361 Other Gastrointestinal Lymphomas imitri Flieger, Ralf Keller, Wolfgang Fischbach Results of the German Randomised Prospective W1362 Multicenter Study in 42 Patients with Localized Primary Gastric B-Cell Lymphoma Maria-lisabeth Goebeler, Axel Greiner, Manfred Stolte, Hans-Konrad Mueller-Hermelink, Wolfgang Fischbach High Frequency of Chromosome X Gains Is W1363 Characteristic of Gastric MALT Lymphoma: Comparative Genomic Hybridization Using Gene-Cluster Analysis Hala 1-Zimaity, Tsutomu Katsuyama, Leif Peterson, James Luca, Hiro Ota, Massimo Ruggae, Maha 1-Zimaity, avid Graham The Clinical Course of Long Followed up Gastric Malt W1364 Lymphoma After Antibacterial Treatment and/or Radiotherapy Hiroyuki Okada, Tomoki Inaba, Yoshiro Kawahara, Masahiro Nakagawa, Junji Shiode, Jun Tomoda, Jun Kato, Hirofumi Kawamoto, Motowo Mizuno, Kenji Yokota, Tadashi Yoshino, Yasushi Shiratori Introduction of nhanced Antiretroviral Therapy Has W1365 Altered the Natural History and Risk Factors Associated with Gastrointestinal Lymphoma Christopher N. Andrews, Stefan Urbanski, Carla Nash, M. John Gill, Paul L. Beck AM-5:00 PM Hall F ~,~ "%lj- Sponsored by: Gastrointestinal Oncology NURONOCRIN TUMORS Pancreatic Neuroendocrine Tumors: The ffect of W1366 Surgical and Medical Therapy on Survival Paola Tomassetti, Raffaele Pezzilli, Lydia Piscitelli, avide Campana, Rosa Ceciliato, Roberto Corinaldesl Hepatic Intra-arterial 9 Y-OTA-lanreotide: A Novel W1367 Treatment for Gastroenteropancreatic (GP) Neuroendocrine Tumours Mar}, K. McStay, ave Maudgil, Jon Tibballs, John Buscombe, Martyn Caplin Long-Term fficacy of Radionuclide Therapy in Patients W1368 with isseminated Neuroendocrine Tumors Uncontrolled by Conventional Therapy Charles Nguyen, Marc Faraggi, Thomas Aparicio, Michel Mignon, Serge Askienazy, Iradj Sobhani AM-5:00 PM Sponsored by: Gastrointestinal Oncology PANCRATIC CANCR: CLINICAL W1369 W1370 W1371 W1372 W1373 W1374 Hall F What Is the Influence of Bile Infection on the arly Postoperative Course After Pancreaticoduodenectomy? Alexandre Cortes, Alain Sauvanet, Frederic Bert, Sylvie Janny, Philippe Ponsot, Reza Kianmanesh, Philippe Ruszniewski, Jacques Belghiti Heme Oxygenase-1 (HO-1) Inhibition Sensitize Pancreatic Cancer to Adjuvant Treatment Pascal O. Berberat, Zilvinas amrauskas, Antanas Gulbinas, Thomas Giese, Nathalia Giese, Frank Autschbach, Stefan C. Meuer, Markus W. Buechler, Helmut Friess Therapeutic valuation of a Novel Combined Therapy with the Oral Fluorouracil Preparation S-1 and Cisplatin in Patients with Inoperable Pancreatic Cancer Akiko Ishibashi, Kyoko Shimizu, Yukiko Takayama, Kazuhiko Hayashi, Keiko Shiratori ffect of TNFerade Local Gene Therapy on xpression of Tumor Necrosis Factor Alpha (TNF-~) and Survivin in Tumors of Patients with Pancreatic Cancer: Can We Prove and Predict Response to Therapy? Kenneth J. Chang, Shirley Yi Shen, Mai Gu, Woo Sung Moon, Randall Holcombe, ric H. Radany, Scan Cao, lyse M. Roth, Chi Wang Lee, Andrzej S. Tarnawski Ras Peptide Vaccination in Reseeted Pancreatic Cancer Patients; Safety, Immune Response and Survival Synne Bernhardt, Marianne K. Gjertsen, Mona Moeller, Jon Around riksen, Odd Soereide, Ivar Gladhaug, Arne Bakka, Gustav Gaudernack, Trond Buanes Allogeneic Reduced Intensity Stem Cell Transplantation for Advanced Pancreatic Cancer Yutaka Komatsu, Yoshinobu Kanda, Masaaki Akahane, Yousuke Nakai, Natsuyo Yamamoto, Kenji Hirano, Hiroyuki Isayama, Minoru Tada, Takao Kawabe, Kuni Otomo, Hisamaru Hirai, Masao Omata enotes W Poster of istinction P-265

72 POSTR SSSIONS--CLINICAL SCINC W N S A Y MAY 19 W1375 W1376 Pretreatment with Gemcitabine and Cyclooxygenase-2- Inhibitors Sensitizes Pancreatic Carcinoma Cells to Cytotoxic T Cell Responses Induced by Tumor-Lysate Pulsed endritic Cells Marc auer, Jan Herten, Katharina Schad, Sabina igenbrod, Stefan ndres, Andreas igler Barriers to Acceptance of a Pancreatic Cancer Surveillance Program in Familial High-Risk Individuals Robert C. Kurtz, Sumera awood, Sara Olson AM-5:00 PM Hall F ~--~5 Sponsored by: Imaging and Advanced Technology AVANC IMAGING OF COLON POLYPS AN YSPLASIA Rectal Aberrant Crypt Foci Identified Using High- W1377 Magnification-Chromoscopic Colonoscopy: Biomarkers for Right-Hemi-Colonic Flat and epressed Neoplasia avid P. Hurlstone, Simon S. Cross, Steven Brown, lan Adam, avid S. Sanders, Kaye rew, Alan J. Lobo Fibered Confocal Fluorescence Microscopy: A New W1378 Route for Ultra High Resolution ndoscopy of the Colonic Mucosa Sacha Loiseau, Benjamin Abrat, Magalie Genet, ric Pehier, Igor Charvet Assessment of the NatUre and Size of Colorectal Polyps W1379 Using Chromo-Magnifying Colonoscopy: A Prospective Study Giuseppe C. Gizzi, Maria A. Pantaleo, Valeria Villani, Raffaele Pezzilli, Barbara Rizzi, Gianfranco pifanio, Rosa Ceciliato, Guido Biasco, Roberto Corinaldesi etailed Morphological Features of Magnifying W1380 ndoscopically Normal Colorectal Mucosa Naoki Wakabayashi, Kazuyuki Toyoda, Keimei Nakano, Satoshi Nishimura, Hideyuki Konishi, Shoji Mitufuji, Takeshi Okanoue High Magnification Chromoscopic Pouchoscopy: A W1381 Novel in vivo Technique for Surveillance of the Anal Transition Zone and Columnar Cuff Following Ileal Pouch Anal Anastomosis avid P. Hurlstone, Simon S. Cross, Steven Brown, Kaye rew, Alan J. Lobo Indigocarmine Chromocolonoscopy Markedly Increases W1382 the etection of Significant Polyps Michael Miros, avid Cohn, Neal Walker The Usefulness of Chromo-Magnifying ndoscopy in the W1383 etection of Colorectal ysplasia in Long-Standing Ulcerative Colitis Giuseppe C. Gizzi, Raffaele Pezzilli, Maria A. Pantaleo, Valeria Villani, Bruno Misitano, Gianfranco pifanio, Guido Biasco, Roberto Corinaldesi Adrenergic Agonist-Induced Calcium Oscillations in the W1384 Nucleus of the Solitary Tract: Laser Confocal Calcium Imaging in the in vitro Brainstem Slice Richard C. Rogers, Jason Nasse, Gregory M. Holmes, Hans- Rudi Berthoud, Gerlinda. Hermann Narrow Band Imaging (NBI) for Improved Pit Pattern W1385 Imaging in Colonic Polyps velien ekker, Mohamed nnabachi, Mohammed A. Kara, Paul Fockens, Sander J. van eventer, Jacques J. Bergman W1386 W1387 W1388 Characterization of Normal and Adenocarcinoma of Human Colonic Mucosa on Frozen Sections by Laser Raman Microspectroscopy Abdelilah Beljebbar, Pierre-Jose Guillou, aniel udes, Jean- Pierre Palm, Olivier Bouche, Marie aniele iebold, Michel Manfait, Gerard Thiefin Intraoperative Fourier Transform Infrared Spectroscopy Can Guide Individual Resections in Patients with Gastric Cancer L. Zhang, K. H. Sun, Roger. Soloway, X.-F. Ling, Y.-Z. Xu, Q.-G. Wu, S. F. Weng, Z. L. Yang, T. L. Zhang, G. Q. Yao, H. H. Chen, X.-S. Zhou,.-F. Xu, J.-G Wu Use of a Fourier Transform Infrared (FT-IR) Mid-IR Fiberoptic Attenuated Total Reflectance (ATR) Probe to etermine Malignancy in Submucosal Oral Tumors Y.-Z. Xu, Y.-F. Zhang, X. Peng, Q.-B. Li, Roger. Soloway, K. H. Sun, W.-J. Zhou, Y. Zhao, Z. L. Yang, G.-Y. Yu, J. Wang, J.-G. Wu AM-5:00 PM Hall F <~ Sponsored by: Immunology, Microbiology & Inflammatory Bowel isorders IB UNCONTROLL THRAPUTIC OBSRVATIONS IN HUMANS Long-Term fficacy of Azathioprine (AZA) in Crohns W1389 isease (C) Beyond 4 Years - a uropean Multicenter Study in 818 Patients Martin H. Hohmann, Frank Krummenauer, Christina Claas, Kristina Kremeyer, irk Lorenz, Olivia Rainer, Iris Vogel, Norbert Luegering, Guido Gerken, Wolfgang Kruis, Stephan Boehm, Oliver Schroeder, Ulrich Boecker, Max Reinshagen, Jan Schmidt, Hans Herfarth, Andreas Stallmach, Rainer uchmann, Carsten Buening, Andreas Sturm, Peter R. Galle, Paul Rutgeerts, aan W. Hommes, Geert Haens, Markus Neurath Safety of Repeated Cycles of Sargramostim in Patients W1390 with Moderately-To-Severely Active Crohn's isease (C): xperience from an Open Label xtension Trial Joshua Korzenik, Christian Stone, John Valentine, iana Hausman Probiotics (VSL#3) in Arthralgia. Preliminary Results of W1391 an Ongoing Open Trial in Patients with Ulcerative Colitis and Crohn isease Ouafae Karimi, Amado Pena, Adriaan A. van Bodegraven Rapid Improvement of Bone Metabolism in Crohns W1392 isease After Infliximab Treatment Virginie Putzeys, Nathalie Franchimont, Julien Collette, Severine Vermeire, Paul Rutgeerts, Martine evos, Andre VanGossum, Rene Fiasse, Paul Pelckmans, Michel Malaise, Jacques Belaiche, douard Louis Improved Outcome Over Time in Patients With an W1393 llealpouch Anal Anastomosis (IPAA) Robin S. McLeod, Zane Cohen, Helen M. MacRae, Brenda O'Connor, Maria Liu P enotes W Poster of istinction

73 POSTR SSSIONS~CLINICAL SCINC W1394 W1395 W1396 W1397 W1398 W1399 W1400 W1401 W1402 W1403 W1404 W1405 W1406 Steroid Therapy in the Age of Infliximab (IFX): Immediate & 1 Year Outcome in Newly iagnosed Children with Crohn isease (C): xperience of the Pediatric IB Collaborative Research Group James Markowitz, Joel Rosh, Jeffrey Hyams, Athos Bousvaros, J. Femando el Rosario, Jonathan vans, Richard J. Grand, Anne Griffiths, Aubrey Katz, Subra Kugathasan, avid Mack, Adam Mezoff, Maria Oliva- Hemker, Anthony Otley, Marian Pfefferkorn, Robert Rothbaum, Vasundhara Tolia, William Treem, Robert Wyllie, Sandra Hale Cytomegaloviral Infection in Refractory Ulcerative Colitis He June Song, Sang Gyun Kim, Kee on Choi, Joe Sung Kim, Hyun Chae Jung, In Sung Song Rofecoxib and arly Relapse of Inflammatory Bowel isease Patients with Associated Arthralgias: An Open- Label Trial Livia Biancone, Claudio Tosti, Francesca e Nigris, Sara merenziani, Carmen Petruzziello, Francesco Pallone Rifaximin-Ciprofloxacin Combination Therapy Is ffective in Patients with Chronic, Active, Refractory Pouchitis Ayman S. Abdelrazeq, Jonathan N. Lund, Scan M Kelly, Stephen H. Leveson Successful Apheresis Therapy in Active Steroid- Refractory Ulcerative Colitis (UC) Wolfgang Kruis, Julia Morgenstern, R. Loefberg, Max Reinshagen, Alberto Malesci, Maurizio Vecchi, Stefan Schreiber, Joachim Moessner, Axel ignass Colesevelam for the Treatment of Bile Acid-Induced iarrhea in Crohn's fsease Patients Intolerant of Cholestyramine Joshua F. Knox, arius Rose, Jeanne mmons, Judy Podoll, Kia Saeian, Tan Attila, Ray K. Cross, avid G. Binion The Use of ndoscopic Ultrasound (US) to Guide Combination Medical and Surgical Therapy for Crohn's (C) Perianal Fistulas avid A. Schwartz, Chris M. White, Amy Artrip, Jackie Beekley, Alan J. Herline Cinnamon and Benzoate Free iet as Primary Treatment of Ore-facial Granulomatosis Miranda Lomer, Alison White, Mike scudier, Kate Barnard, Pepe Shirlaw, Stephen Challacombe, Jeremy Sanderson Intentional Infliximab Use for Maintenance or Acute Crohns isease(c)flare in Pregnancy Uma Mahadevan, Sunanda Kane, William J. Sandborn, Russell. Cohen, Karen Hanson, Jonathan P. Terdiman, avid G. Binion Meropenem Improves Complex Perianal Crohn's isease Refractory to lnfliximab J. J. Theal, M. A. Haider, G. R. Greenberg Long Term fficacy and Toxicity of Thalidomide in Crohn's isease Marion Simon, Jean-Marc Gomet, C. Plane, Matthieu Allez, Jean-Frederic Colombel, Jean Marc Sabate, Antoine Cortot, Robert Modigliani, Marc Lemann Successful 1 Hour Infusions of Infliximab for Crohn's isease Patients in an Outpatient Office Setting Bruce A. Salzberg, Karen Kendall Cyclosporine in Crohn's and Indeterminate Colitis - a Five Year xperience at Cedars-Sinai Medical Center, Los Angeles Andrew Ippoliti, Maria Abreu, Phil Fleshner, Kostos Papadakis, Stephan Targan, ric Vasiliauskas W1407 w1408 W1409 w1410 W1411 W1412 W1413 W1414 W1415 W1416 W1417 W1418 Prospective, Open, Pilot Study of Granulocytapheresis (GCAP) for the Treatment of Steroid-ependant Inflammatory Bowel isease: Preliminary Results ugeni omenech, Joaquin Hinojosa, Maria steve, Femando Gomollon, Jose Manuel Herrrera, Pilaf Nos, Antoni Obrador, Rebeca Ruiz, Cristina Saro, Miquel A. Gassull Adsorptive Granulocyte and Monocyte Apheresis Therapy for Refractory Crohn's isease: An Open Multicentre Prospective Study Yoshihiro Fukuda, Toshiyuki Matsui, Yasuo Suzuki, Kazunari Kanke, Takayuki Matsumoto, Masakazu Takazoe, Takayuki Matsumoto, Satosbi Motoya. Terasu Honma. Koii Sawada, Ken Fukunaga, Tsuneyoshi Yao, Takashi Shimoyama, Toshifumi Hibi Clinical Features Cannot Be Used to Predict Crohn's isease in Patients with Ileoanal Pouches Rahul K Chhablani, Mical S. Campbell, Chin vu qu. ]uhu, eren, avid Katzka, John L Roml~eau, \1orc}e N tt>l~al,n/ Howard Ross, Gary R. Lichtenstein imethylsulfoxide Using for Systematic Secondary Amyloidosis Complicated in Chronic Inflammatory isease Sadahiro Amemori, Ryuichi iwakiri, Akifumi Ootani, Atsushi Kikkawa, Hiroyoshi Fndo, Takehh-o Fu.ii~e, bhin Nakahara, Kqi Fukuyama, Yoshihiro riguuhi. Tsunada Seiji, Hiroyuki Sakata, Kazulna Fuiimoto fficacy of 6-Thioguanine in Patients with Crohn's isease Intolerant to Azathioprine omagoj lvastinovic, Christoph Hoegenauer, Wolfgang Petritsch, Heimo H. Wenzl, Thomas A. Hinterleimer Management of Ponchitis of the Ileoanal Pouch with Infliximab Sanjib P. Mohanty, Anthea arling, Kim L. Isaacs 6-MP Metabolite Interacts with Purine Analogs in Patients with Inflammatory Bowel isease Motoko Izumiya, Shigeo Yoshizawa, Tomoharu Yajima, Hisamatsu Tadakazu, Okamoto Susumu, Hiromasa Takaishi, Nagamu Inoue, Haruhiko Ogata, Yasushi Iwao, Toshifumi Hibi Maintenance of Long Term Response to Infliximab over 1 to 5 years in Crohn's isease Including Shortening osing Intervals or Increasing osage Christopher. Shih, Theodore M. Bayless, Mary L. Harris Premeditation and Infusion Reactions with Infliximab: Results from a Pediatric Inflammatory Bowel isease Consortium Jonathan. Markowitz, George. Ferry, Barbara S. Kirschner, Harland S. Winter, Stanley A. Cohen, Benjamin. Gold, Melvin B. Heyman, Petar Mamula, Melissa A. Shepanski, Terry Smith, Pat L. Fain, Robert N. Baldassano Seven Years on: Living with Inflammatory Bowel isease Sally Skinner, Christopher Hawkey, Charlie Charlton, Harriet Gross, avid Middleton elayed Hypersensitivity Reactions Following Iufliximab Infusion. Analysis of Risk Factors Gregory Bonner, Marcia Cruz-Correa Centrifugal Leukocytapheresis Therapy Without Concurrent Corticosteroid Administartion for Ulcerative Colitis Hiroyuki Okada, Jun Kate, Shin-Ichiro Hori, Ryuuta Takenaka, Sakiko Hiraoka, Aktko Fujiwara, Chiho Makidono, Hirofumi Kawamoto, Motowo Mizuno, Yasushi Shiratori enotes W Poster of istinction P-267

74 W N S A Y MAY 19 W1419 W1420 Long Term Oral Cyclosporine Therapy in Severe, Steroid Refractory Ulcerative Colitis with a aily ose of 4 mg/kg - Result of the One-Year Follow-up Tamas Molnar, Ferenc Nagy, Janos Lonovics fficacy of Granulocyte and Monocyte Adsorption Apheresis in Chronic Active Crohn's isease Sebastian Petermann, Wolfgang Ramlow, Stefan Liebe, Joerg mmrich AM-5:00 PM Hall F ~,~ Sponsored by: Motility & Nerve-Gut Interaction SOPHAGAL MOTILITY, SNSATION AN ISORRS The Metabotropic Glutamate Receptor 5 Antagonist W1421 MPP Inhibits Transient Lower sophageal Sphincter Relaxations in the og Jorgen Jensen, Anders Lehmann, Malin Hulander, Anna Uvebrant, Anita Carlsson, Mia Umaerus, Karolina Nilsson, Claudine Frisby, L. Ashley Blackshaw, Jan Mattsson sophago-upper sophageal Sphincter Contractile W1422 Reflex (UCR) and Secondary sophageal Peristalsis (2 P) uring NRM and RM Sleep Jasmohan S. Bajaj, Kulwinder un, Shailesh Bajaj, Tanya Rittmann, Reza Shaker Apnea uring eglutition and Gastroesophageal Reflux W1423 in Infants: It's All About the Bolus Tobias G. Wenzl, Michael Welter, Thomas Peschgens, Melanie Ahaus, Gerhard He/mann Subtypes of the Capsaicin-Sensitive Vagal C-fibers in W1424 Guinea Pig sophagus Shaoyong Yu, Marian Kollarik, Brian. Lacy, Bradley J. Undem Rho Kinase Mediates Thromboxane A2 (TXA2)-Induced W1425 Sustained Contraction in Cat Lower sophageal Sphincter (LS) Weibiao Cao, Karen M. Harnett, Ling Cheng, Jose Behar, Piero Biancani A Measure of Achalasia isease Severity W1426 avid Urbach, George Tomlinson, Julie Hamish, Rosemary Martino, Nicholas iamant eterioration of Airway Protective Reflexes W1427 Accompanied by Absence of Arousal Response to Pharyngeal Water Stimulation: A Recipe for Aspiration Kulwinder S. ua, Jasmohan S. Bajaj, Tanya Rittmann, Candy Hofmann, Reza Shaker High-Resolution Manometry (HRM) Improves the W1428 etection of Incomplete Lower sophageal Sphincter Relaxation (ILSR) Annamaria Staiano, Ray. Clouse Fundoplication Reduces sophageal Longitudinal Muscle W1429 but not Circular Muscle Function Qing Zhang, Peter J. Kahrilas, Sunil T. Joseph, Guoxiang Shi, John Pandolfino, Ikuo Hirano Increased sophagogastric Junction (GJ) Bolus Transit W1430 Time Is Related to Postfundoplication ysphagia Bob Scheffer, Melvin Samsom, Alexander Haverkamp, Jac Oors, Geoff Hebbard, Hein Gooszen POSTR SSSIONSmCLINICAL SCINC W1431 W1432 W1433 W1434 W1435 W1436 W1437 W1438 W1439 W1440 W1441 W1442 HCl-lnduced IL-6 and H20~ in Cat LS in an in vitro Model of xperimental sophagitis Ling Cheng, Karen Harnett, Weibiao Cao, Jose Behar, Piero Biancani Comparison of sophageal Sensory Testing, Clinical Characteristics and Psychometric Profile Between Patients with Nonerosive Reflux isease (NR) and Abnormal ph Testing and Those with Functional Heartburn (FH) Ronnie Fass, Joy N. Beeler, Isaac B. Malagon, Jimmy M. Bautista High-Resolution Manometry (HRM) Reveals Bolus ntrapment in the Proximal sophagus with ouble Swallows in Patients with Spastic Motor isorders (SM) Clinton T. Snedegar, Laura R. Haroian, Ray. Clouse Barrett's sophagus After Pneumo-dilation For Achalasia Pieter Scholten, Yvonne Leeuwenburgh, Rob Vaessen, Thomas Calje, velien Ong, Peter. Siersema, Jelle Haringsma, rnst J. Kuipers Basal and Provocative Pharyngo-sophageal Reflexes Are Impaired in Infants with Perinatally Acquired Neurological Injury Sudarshan R. Jadcherh, Alankar Gupta, Reza Shaker valuation of the Upper sophageal Sphincter (US) In Normal Volunteers and Human Cadavers Using Simultaneous High-Resolution ndoluminal Sonography (HRS) and Manometry Qing ai, Larry S. Miller, Brett Sweitzer, Vinod Thangada, Joseph Kim, Beje Thomas, Henry Parkman, Ahmed Soliman Simultaneous Ultrasound (US) and Manometry uring Pharmacologic Paralysis of the Crural iaphragm Allows Spatial Localization of the Two Components of the Intrinsic Gastroesophageal Junction High Pressure Zone (GJHPZ) Qing S. ai, Ahmed S. Soliman, ilipkumar Patel, Vinod Thangada, James Brasseur, Chan Chung, Rhys Ulerich, Henry Parkman, Beje Thomas, Larry S. Miller Acid Reflux Therapy Improves Cardiac Symptoms in a Subgroup of GR Patients with Idiopathic Arrhytmias and Altered Neurocardiac Function Rosario Cuomo, Francesco e Giorgi, Giovanni Sarnelli, Lorenzo Adinolfi, onatella Iannuzzo, Clelia Verde, Gabriele Budillon Reversibility of Pharyngo-US Contractile Reflex (PUCR) and Reflexive Pharyngeal Swallow (RPS) in xsmokers Kulwinder S. un, Jasmohan Bajaj, Jo Weiss, James Hasting, Tanya Rittmann, Candy Hofmann, Reza Shaker Asymmetrical Mechanisms Controlling Resting Tone, Relaxation and Contraction in Clasp and Sling Regions of Porcine LS Ricard Farre, mma Martinez, Xavier Sunyol, Pere Clave iscoordination Between Circular and Longitudinal Muscle Contractions in Patients with High Amplitude sophageal Contractions Hwoon-Yong Jung, James L. Puckett, Vikas Bhalla, Maria Rojas, Valmik Bhargava, Jianmin Liu, Ravinder K. Mittal Mechanisms of Incomplete Bolus Transit in Non- Obstructive ysphagia Assessed by Combined Multichannel Intraluminal Impedance and Sleeve Sensor Manometry Jose M. Conchillo, Nam Q. Nguyen, Melvin Samsom, Richard H. Holloway, Andre J. P. M. Smout P enotes W Poster of istinction

75 v POSTR SSSIONS~CLINICAL SCINC W1443 W1444 Nonerosive Reflux isease (NR) in Patients with Non Cardiac Chest Pain (NCCP) Amedeo Indriolo, Francesco Negrini, Sergio Signorelli, Maria Grazia Luca, Mario Strazzabosco Longitudinal and Circular Muscle Contract Synchronously in the sophagus during Peristalsis: A New Way to Look at the Contraction of Two Muscle Layers Vikas Bhalla, Bikram Padda, James Puckett, Jianmin Liu, Neelesh A. Tipnis, Ravinder K. Mittal AM-5:00 PM Half F (~ Sponsored by: Motility & Nerve-Gut Interaction PHARMACOTHRAPUTICS IN FUNCTIONAL GI ISORRS W1445 W1446 W1447 W1448 W1449 W1450 W1451 W1452 Novel Solid-State Technology Simplifies High-Resolution Manometry (HRM) for Clinical Use Ray. Clouse, Thomas R. Parks, Laura R. Haroian Combined Multichannel Intraluminal Impedance and Manometry Clarifies the Function efect in Patients with istal sophageal Spasm Radu Tutuian, onald O. Castell Prospective Follow-up of Patients with Nonspecific sophageal Motility isorders Thomas Schmitt, Bjoern Goepel, Volker ckardt ffect of Buspirone, a 5HTIA Receptor Agonist, on Oesophageal Peristalsis and Lower Oesophageal Sphincter Function in Healthy Volunteers Michele i Stefano, Rita Vos, aniel Sifrim, Jozef Janssens, Jan Tack Concurrent Video-sophagram, Impedance Monitoring, and Manometry in the Assessment of Bolus Transit in Normal Subjects Hala Imam, Mark Baker, Steven Shay Simultaneous Barium sophagram (Ba), Impedance Monitoring (Imp) and Manometry (Ba-Imp-Manometry) in Patients with ysphagia ue to a Tight Fundoplication Hala Imam, Mark Baker, Steven Shay Comparison of Air Coupled Balloon sophageal Manometry Catheters with Solid-State sophageal Manometry Catheters John Fang, Kristen Hilden, Ashok Tuteja, Kathryn Peterson Bitter and Sweet Tastes Have Bidirectional Influences on Human Swallowing Cortical Motor Pathways Satish Mistry, avid Gow, John Rothwell, avid G. Thompson, Shaheen Hamdy The Study of Neuronal NOS Gene Polymorphism in sophageal Motility isorders J. S. Lee, Y. S. Kim, J.. Lee, I. S. Jung, Bong Min Ko, Su Jin Hong, Chang Beom Ryu, Jo Kim, Joo Young Cho, M. S. Lee, Chan Sup Shim, Boo Sung Kim W WI457 W W1459 W1460 W1461 W1462 ffects of the SSRI, Fluoxetine (Prozac), on Regional Gastric Contractility Arlene N. James, James P. Ryan, Henr)' P. Parktmm fficacy and Safety of Renzapride in Patients with Constipation-predominant IBS: A Phase llb Study in thc UK Primary Heahhcare Setting Nicholas L. Meyers, Richard M. J. Palmer, :\lun i,'o~4c A Fixed Combination of Peppermint- and Caraway Oil Modulates Postinflammatory Visceral tlyperalgesia Gerald Hokmann, Birgit Adam, Tobiab Lid~regt_,. cnni> Ruprecht, Marx Awasung, Jan Best, Lars P Bechmanu, /-,~m Tuan Tran A Meta-Analysis of the Clinical fficacy and Safety of a New Class of Laxatives Containing High Molecular Weight Polyethylene Glycol in Patients with Chronic Constipation Hans-Juergen Gruss, Marc Halphen ATI-7505 Is a Novel, Selective 5HT4 Receptor Agonist That Causes Gastrointestinal Prokinetic Activity in ogs onn ennis, Monica Palme, Ian Irwin, Pascal ruzgala, Sam Teichman The Selective Mu Opioid Receptor Antagonist, Alvimopan, Accelerates Gastrointestinal Transit in a Rodent Model of Postoperative lleus Hiroyuki Fukuda, Kiyotaka Suenaga, Kenichiro Uemura, aisuke Tsuchida, Christopher R. Mantyh, Theodore N. Papas, Gareth A. Hicks, Toku Takahashi Short Chain Fatty Acids Induce Motor Responses in the Rat Isolated Gastrointestinal Tract Via the 7-TM Receptor GPR43 Narinder ass, Gary Moore, Christopher Crumbley, Anna Bassil, Andrew Brown, Gareth Sanger W1453 W1463 Prokineticin-2, a Potential Novel Protein Therapeutic, Increases Post-Operative Gastric and Intestinal Motility in Rats Katherine. Lewis, Richard M. Garcia, Kyung-Hoon Kim, Robert R. West, Penny J. Thompson, ebra G. Gflbertson W1454 W1455 Gastroesophageal Reflux isease in iabetics Lubomir Michalko, Boris Krahulec, Charles Antwi, Stela Hlinstakova sophageal Protective Reflexes Are Altered in Infants with GR Sudarshan R. Jadcherla, rin Stoner, Colin. Rudolph, Reza Shaker W1464 W1465 oes Co-Morbid Irritable Bowel Syndrome Influence the ffectiveness of PPI Therapy for Gastroesophageal Reflux isease? William. Chey, Borko Nojkov, Susan Adlis, John lnadomi, Michael J. Shaw Types of Medications Used for Irritable Bowel Syndrome (IBS): Outcomes, Patient Satisfaction and Side ffects William. Whitehead, Olafur S. Palsson, Rona L. Levy, Andrew. Feld, Michael Von Korff, Michael Shetzline, Marsha J. Turner W1466 Renzapride Accelerates Colonic Transit and Improves Bowel Function in Constipation-Predominant Irritable Bowel Syndrome (C-IBS) Michael Camilleri, Sanna McKinzie, Jean Fox, Amy Foxx- Orenstein, uane Burton, George Thomforde, Karl Baxter, Alan Zinsmeister enotes W Poster of istinction P-269

76 POSTR SSSIONS--CLINICAL SCINC I W N S A Y MAY 19 W1467 W1468 W1469 W1470 W1471 W1472 W1473 W1474 W1475 W1476 W1477 Physiological and Psychosocial ffects of esipramine (S) Treatment Response in Functional Bowel isorders (FB) Yehuda Ringel, William. Whitehead, Nicholas. iamant, Carolyn B. Morris, Yuming Hu, Brenda B. Toner, Shrikant Bangdiwala, ouglas A. rossman AM-5:00 PM /~:r~,, Long-Term Safety and Tolerability of Tegaserod in Chronic Constipation (CC) Stefan Mueller-Lissner, Michael Kamm, Peter Haeck, Ahmet Musoglu, Martin Huorka, Juliette Guillot, Julie Jones, Brigitte Nauh W1478 Tegaserod is ffective in Relieving the Multiple Symptoms of Chronic Constipation (CC): Pooled ata from Two Phase III Studies Karna Bardhan, Ronald Schwarz, Maria Kanty-Okulewicz, Julie Jones, Sophie Hugot, Brigitte Nault W1479 Tegaserod Significantly Improves Bloating in Female Irritable Bowel Syndrome Patients with Constipation (IBS-C) Peter Whorwell, Peter Rueegg, avid arnest, Cornelia unger-baldauf W1480 Cilansetron, a Novel 5-HT3 Antagonist, emonstrated fficacy in Males with Irritable Bowel Syndrome with iarrhea-predominance (IBS-) Georges Coremans, Ray. Clouse, Fred Carter, Guenter ' Krause, Steven Caras, Claus Steinborn W1481 Alvimopan (ALV) Shortens Whole Bowel Transit Time in Adults with Chronic Constipation (CC) William Garnett, ennis L. Kelleher, Fiona Hickmott, William Barr, Alvin Zfass, Glendolynn Sanderlin, Shane Coots, LeaAnn Hansen, George ukes W1482 Tegaserod Improves Gastric mptying and Alters Myoelectrical Activity in yspeptic Patients Ivo R. van der Voort, Marco Schmidtmann, Kilian Fach, Christoph Werner, Viola Andresen, Bertram Wiedenmann, Burghard F. Klapp, Hubert Moennikes Sponsored by: Nutrition & Obesity NTRAL AN PARNTRAL NUTRITION O W1483 Human Visceral Pain Hypersensitvity Is Independent of Cyclo-oxygenase-2 (COX-2) W1484 Robert Willert, Claire elaney, Anthony Hobson, avid Thompson, Qasim Aziz Omeprazole Slows Small Intestinal Transit (SIT) in Mice and Concomitant Tegaserod Antagonizes This ffect Alan Cowan, avid arnest, Mikhail Rojavin W1485 A Phase lib Clinical Study Of Renzapride in Mixed- symptom (Alternating) Irritable Bowel Syndrome W1486 Jane C. Henderson, Richard M. J. Palmer, Nicholas L. Meyers, Robin C. Spiller Spasmolytic Agents for the Treatment of Irritable Bowel Syndrome; a Meta-Analysis A. Otto Quartero, Nick J. de Wit, Villy Meintche-Schmidt, Jean W. M. Muris, Greg Rubin W1487 W1488 W1489 Hall F The ffect of Severe Malnutrition and Subsequent Refeeding on Whole Body Metabolism and Protein Synthesis in Human Subjects Trevor A. Winter, Stephen O'Keefe, Marie Callanan, Tessa Marks Survival Rate and Prognostic Factors in Patients with Intestinal Failure Italo Vantini, Luigi Benini, Fabrizio Bonfante, Giorgio Talamini, Carlo Sembeuini, Giuseppe Chiarioni, Franco Benini, Franco Capra Contemporary Rates, Risk Factors and Outcomes of Parenteral Nutrition-associated Hepatic ysfunction in Infants Timothy A. Sentongo, Roopa Seshadri, Kishore Iyer, Robin Steinhorn ffect of Intravenous Pamidronate in Home Parenteral Nutrition Patients wth Short Bowel Syndrome: Improvement in Bone Mineral ensity John K. Siepler, Reid Nishikawa, Stacy Siepler, Tom iamantidis, Rod Okamoto Intestinal Failure - Outcomes of Rehabilitation Clarivet Torres, ebra Sudan, Simon Horslen, Wendy Grant, Jean Botha, Alan Langnas When Should We Start with Total Parenteral Nutrition? Michael Momma, Johann Ockenga, Gernot Sellge, Michael P. Manns, Stephan C. Bischoff Survey of Nutrition Management Practices of Canadian Gastroenterologists Harminder Singh, onald R. uerksen nteral Nutrients Are More fficiently Utilized for the Synthesis of igestive nzymes and Mucosal Proteins Than Parenteral Nutrients in Humans Stephen J.. O'Keefe, Ronzo B. Lee, Jing Li, Neeraj Kaushik Proton Pump Inhibitors Are Only ffective in the Short Term for Preventing PG Site xcoriation Janet earden, ebra Grant, Nial van Someren Increased Plasma Arginine and Citrulline to nteral and Parenteral Infusion of L-Alanyl-L-glutamine in Preoperative Patients Petra Boelens, Gerdien Melis, Hubert Prins, Joost van der Sijp, Paul van Leeuwen Parenteral Nutrition Survival and ependence in a National Referral Center Roser Vega, Chryssostomos N. Kalantzis, Georgios Karamanolis, Wendy Lim, Cinzia Papadia, imitrios Polymeros, Alastair Forbes, Simon Gabe Glucose Transport Is Upregulated in istal Ileum Concomitant with Adaptive Small Intestinal Growth After Massive Small Bowel Resection in Mice Naohiro Washizawa, Mary. vans, Li H. Gu, Thomas R. Ziegler P-270 ~ enotes W Poster of istinction

77 w POSTR SSSIONS--CLINICAL SCINC W1490 W1491 W1492 Gut Mucosal Glutathione Status ifferentially Regulates Ileal and Colonic Mucosal Growth in a Rat Model of Short Bowel Syndrome Junqiang Tian, Naohiro Washizawa, Li Gu, ean P. Jones, Thomas R. Ziegler Can nteral Nutrition Provide Adequate Stress Prophylaxis for Patients on Mechanical Ventilation? Stephen A. McClave, avid A. Spain, James K. Lukan, Cindy C. Lowen, Gerald W. ryden Three Main ietary Fibers, Cellulose, Resistant Starch and Pectin, xhibit Major ifferences in the Amounts Which Reach the Large Intestine Takao Oyama, Shigeyuki Nakaji, Shinsaku Fukuda, Juichi Sakamoto, Tadashi Shimoyama, Kazuma anjo, aisuke Saito, aisuke Chinda, Akihiro Munakata ASG Poster Session Authors are required to be present during the Poster Session from 12:00-2:00 pm. AM-5:00 PM Hall F W1502 W1503 W1504 W1505 W1506 Temporary Placement of the Polyflex Stent for the Treatment of Refractory Benign sophageal Strictures Alessandro Repici, Massimo Conio, Claudio e Angelis, dda Battaglia, Alessandro Musso, Rinaldo Pellicano, Matteo Goss, Cloe alla Costa, Stefania Caronna, Giorgio Saracco, Mario Rizzetto ndoscopic Resection of Submucosal Tumors of the sophagus. A Prospective Case Series Till Wehrmann, Ksenia Martchenko, Andrea Riphaus, Nikos Stergiou Clinical and ndoscopic Features of Patients with sophageal Membranes and Rings Volker F. ckardt, Susanne Kuech, Thomas Schmiu. Gudrun Bernhard oes an Administration Technique of Botulinum Toxin (BT) Injection Matter? Final Results of a Randomized, ouble-blind Study in Patients with Non-advanced Achalasia Jan Martinek, Marek Benes~ Milan Siroky, Julius >picak. Pavel rastich, Jan Bures Food and Foreign Body Impactiou In Upper GI Tract M Yasser F. Abu-Safieh SOPHAGUS Unsedated Peroral Small-Caliber ndoscopy for W1493 Screening of Cirrhotics for sophageal Varices (V) Curuchi P. Anand, Judy Lindsey, Florinela Oprescu, Terence Angtuaco, Sandeep Bhargava, Vivek Raj Combined Treatment - Botulinum Toxine and Pneumatic W1494 ilation in Patients with Achalasia - Long Term Results Radek Kroupa, Ales Hep, Jiri olina, Zuzana Matyasova, Vlastimil Valek Lower sophageal Sphincter Pressure and Timed W1495 Barium sophagogram, Two Objective Parameters in the Assessment of Achalasia Reza Malekzadeh, Ghodratollah Montazeri, Mohamad H. erakhshan, Shapoor Shirani, Javad Mikaeli, Arezoo stakhri ndoscopic Management of Zenker's iverticulum: A W1496 Gastroenterologist Approach Isaac Raijman Sr., Susan scalante, Claudio Navarrete A Randomized, Prospective Trial of lectrosurgical W1497 Incision Followed by Rabeprazole Versus Bougie ilation Followed by Rabeprazole of Symptomatic sophageal (Schatzki's) Rings Jason Wills, Kristen Hilden, James A. isario, John Fang - Pill sophagitis Is a istinct ndoscopic ntity vs W1498 Reflux sophagitis - a Case Control Study V. A. Botoman, Nirmala Shanmungan, isa Macapagal, Wisam F. Zakko ffect of Mucosal Sutures on the Muscularis Propria W1499 Layer at the Gastroesophageal Junction Julia J. Liu, Johnathan N. Glickman, John Sahzman lectrocautery Therapy for Refractory Benign W1500 Anastomotic Strictures of the sophagus Marjan L. Hordijk, rnst J. Kuipers ndoscopic Treatment of Anastomotic Strictures W1501 Following Resection of sophageal CA: Increased Success Using Submucosal Corticosteroid Injection Marc F. Catalano, Suku George, Miriam Thomas, Joseph. Geenen ASG Poster Session AM-5:00 PM Hall F Morial Convention Cemet SOPHAGUS W1507 W1508 W1509 W1510 W1511 W1512 W1513 Accurate Localization of nteryx into the eep sophageal Wall Without Fluoroscopy Robert A. Ganz, Mark Rydell, Paul Termin ndoscopic Augmentation of the Lower sophageal Sphincter for GR: Final Results of a uropean Multicenter Study of the Gatekeeper System TM Paul Fockens, Guy Boeckxstaens, Armando Gabbrielli, Guido Costamagna, Jan Hattlebakk, Svein Odegaard, Hans- ieter Allescher, Thomas Roesch, Stefan Muehldorffer, Jean Bastid, Jean Francois Rey, Christophe Bastid ndoscopic Full-Thickness Plication for GR: urability at 12-Months ouglas Pleskow, Richard Rothstein, Simon Lo, Robert Hawes, Richard Kozarek, Gregory Haber, Christopher Gostout, Anthony Lembo Lugol's Chromoendoscopy Improves the etection of sophagitis in Patients with Nonerosive Reflux isease Frederick T. y, Jose. Sollano Jr., Alvin P. Quino, Johnny T. Go, Melchor M. Chan, Victoriano Y. Lim, Carmelita. alupang Spongiosis as a Marker for Gastroesophageal Reflux isease (GR) in sophageal Biopsies Pablo A. Bejarano, Steven A. Simon, Mehdi Nassiri, Miami ndoscopy Center Predictors of nteryx Outcomes at 12 Months Jacques eviere, Lawrence B. Cohen, James Aisenberg, Robert A. Ganz, Glen A. Lehman, T. Raymond Foley, avid A. Johnson, Gregory B. Haber, Jeffrey H. Peters A Prospective Multicenter Phase II Study to valuate ndocynch Suturing System for the Treatment of GR Thierry Ponchon, Jean Boyer, Jean Charles Grimaud, Jean- Christophe Letard, Jean scourrou, Frederick ucrot, Jean Marc Canard, Jean Francois Rey, Group Sled P-271

78 W N S A Y MAY 19 ii W1514 W1515 W1516 W1517 w1518 W1519 W1520 W1521 W1522 W1523 W1524 W1525 W1526 W1527 The Stretta Procedure Improves GR Symptoms and Anti-secretory rug Use at 2 Years, while Normalii:ing Gastric mptying Function in the Majority of Impaired Subjects Mark Noar, Joan Smith 2- and 3- ndoluminal Ultrasound Localization of ndoscopic Plications with Simultaneous Manometry (Location of Plications and epth of Sutures) Qing ai, James G. Brasseur, John imitriou, Chan Chung, Antonia Thomas, Wassim Assari, Larry S. Miller Gatekeeper TM Reflux Repair System: Results of Two Years Follow-Up Armando Gabbrielli, Laura Cipolloni, Monica Pandolfi, Sara merenziani, Michele Cicala, Guido Costamagna Clinical Benefits of nteryx for High-ose PPI Patients avid A. Johnson, James Aisenberg, Lawrence B. Cohen, Robert A. Ganz, Glen A. Lehman, T.: Raymond Foley, Jacques eviere, Gregory B. Haber, Jeffrey H. Peters The Transverse Fold "Flap Valve" at the Gastroesophageal Junction oes Not Prevent Reflux isease When a Hiatal Hernia Is Present Benson T. Massey Comparison of ndoluminal Gastroplicadon Configuration Techniques: A Long Term Study Richard avis, Janese Gerhardt, Rebecca Welch, Charles Filipi The Clinical fficacy of the ndoscopic Suturing evice for Treatment of Gastroesophageal Reflux isease Julia J. Liu, Ria Ookubo, John Sahzman oes ndoscopy Alter Management for Uncomplicated Gastroesophageal Reflux isease? Graham B. Turner, Tony C. K. Tham Study of a Role of Salivary Secretion in Reflux sophagitis in Patients with Scleroderma Tomohiro Kato, Hiroshi Araki, Minoru Nakai, Takafumi Naiki, Takahiko Asano, Hideki Hayashi, Tomoo Naito, Ichiro Yasuda, Masahito Nagaki, Hisataka Moriwaki xtended (48 hr) Monitoring in Patients with xtraesophageal Manifestations of GR Sami R. Achem, Mark. Stark, awn. Ferguson, ric M. Ward, iane M. avis, Susan I. Nedrow, rnest P. Bouras, Herbert C. Wolfsen, avid S. Loeb, Kenneth R. evault First xperience with a New ndoscopic Suture evice (S) for ndoscopic, ndoluminal Therapy of GR ieter Schilling, Ralf Kiesslich, Peter R. Galle, Juergen Riemann Fatty Meal and Alcohol Tolerance Test Using Catheter Free Bravo ph Monitoring System Susumu Kurosawa, Shinko Kato, Teruyuki Tanaka, Shigeo Ozawa, Masakatsu Yosikawa, Rei Kashima, Shino Ohno, Tetsuo bihara, Hideo Kamiichi, Junichi Kawashima, Katsuhiko Tsuda, Koji Yakabi ifferences Between Japanese Patients Having ndoscopic sophagitis with and Without Reflux Symptoms Seiji Kimura, Masanori Tanaka Laparoscopic Antireflux Reoperation: The Case for the Third Antireflux Procedure Aureo L. de Paula, Tulio M.R. Cunha, Luiz Q. Silva, Antonio Luiz V. Macedo, Vladimir Schraibman POSTR SSSIONS--CLINICAL SCINC ASG Poster Session AM-5:00 PM Hall F SOPHAGUS W1528 W1529 W1530 W1531 W1532 W1533 W1534 W1535 Comparison of Argon Plasma Coagulation and Paravariceal Injection Sclerotherapy of 1% Polidocanol in Mucosa-Fibrosing Therapy for sophageal Varices Shigenaga Matsui, Masatoshi Kudo, Tsutomu Ichikawa, Ryousuke Nakaoka, Toshihiko Kawasaki, Mikio Shiomi ndoscopic Treatment of Bleeding Gastric varices by Cyanoacrylate Injection at King Chulalongkorn Memorial Hospital Phadet Noophun, Pradermchai Kongkam, Rungsun Rerknimitr arly and Late Results of ndoscopic Injection of N- Butil-2-Cyanoacrylate in Bleeding Gastric Varices Petruska Marques, Fauze Maluf-Filho, Sergio Matuguma, Paulo Sakai, Shinichi Ishioka ndoscopic Ligation of Oesophago-Gastric Varices with a New Multiple Band Ligator Paola Billi, Andrea Grilli, Costance Mwangemi, anilo Baroncini, Carlo Fabbri, Vincenzo Cennamo, avide Lo Cuoco, Luca e Luca, Nicola 'Imperio Long-Term fficacy of ndoscopic Variceal Ligation for sophageal Variceal Bleeding: The Presence of Portal Hypertensive Gastropathy and Total Number of VL Sessions Were Risk Factors of Rebleeding ong Ho Lee, NaYoung Kim, Jin Wook Kim, Jin-Hyeok Hwang, Young Bum Yoon, in Sung Song, Chung Yong Kim US Features in lder Patient with sophageal Varices; How to Manage for sophageal Varices in ldely? Tadayuki J. Takagi, Atsushi Irisawa, Katsutoshi Obara, Ayako Saito, Goro Shibukawa, Go Yamamoto, Takuto Hikichi, Takeru Wakatsuki, Hidemichi Imamura, Yukio Sato A Prospective Study on Long-term Outcome of Modified VL for Prophylactic Patients with Risky Varices Nobuhiko Nagamine, Kazunori Ono, Kennichi Ido, Kentaro Sugano oes a Change in the Portal Pressure After ndoscopic Variceal Treatment Influence a Long-Term Prognosis? Tadaynki J. Takagi, Atsushi Irisawa, Katsutoshi Obara, Ayako Saito, Goro Shibukawa, Go Yamamoto, Takuto Hikichi, Takeru Wakatsuki, Hidemichi Imamura, Yukio Sato ASG Poster Session AM-5:00 PM Hall F SOPHAGUS W1536 W1537 W1538 Molecular Aberrations Are Still Present After Ablative Therapy of Barrett's sophagus Mariska Hage, Herman van ekken, Kees J. Vissers, Jelle Haringsma, rnst J. Kuipers, Peter. Siersema ndoscopic Ablation of Barrett's sophagus: A Randomized Trial of Photodynamic Therapy (PT) Versus Argon Plasma Coagulation (APC) Clive J. Kelty, Roger Ackroyd, Nicola J. Brown, Timothy J. Stephenson, Christopher J. Stoddard, Malcolm W. R. Reed Successful radication of Barrett's Mucosa With Argon Coagulation and Acid Suppression: Mid Term Results mad Y. Rahmani, Omar Nehme, Kathy Arney, Carolyn Turpin P-272

79 POSTR SSSIONS--CLINICAL SCINC W1539 W1540 W1541 W1542 W1543 W1544 W1545 W1546 W1547 W1548 W1549 Complete Ablation of Porcine sophageal pithelium Using a Balloon-based Bipolar lectrode Robert A. Ganz, avid S. Utley, Roger Stem, Jerome Jackson, Kenneth P. Batts, Paul Termin Photodynamic Therapy for ysplastic Barrett's sophagus and arly sophageal Adenocarcinoma Should be First Line Therapy! mad Y. Rahmani, Carolyn Turpin, Kathy Arney Optimization of Aminolevulinic Acid-based Photodynamic Therapy of Barrett's sophagus with High Grade ysplasia avid G. Forcione, Tayyaba Hasan, Bernhard J. Ortel, Norman S. Nishioka Photodynamic Therapy for ysplastic Barrett's sophagus and Mucosal Adenocarcinoma Herbert C. Wolfsen, Lois L. Hemminger Relationship Between Acute Mucosal Injury, Treatment fficacy and sophageal Stricture Following Photodynamic Therapy of Barrett's sophagus Masoud Panjehpour, Mary N. Phan, Bergein F. Overholt ndoscopic Resection Combined with Photodynamic Therapy for High Grade ysplasia and arly Cancer in Barrett's sophagus Femke Peters, Mohammed Kara, Wilda Rosmolen, Fiebo ten Kate, Bert Bultje, Sheila Krishnadath, Paul Fockens, Jan van Lanschot, Sander van eventer, Jacques Bergman Interim Results of a Randomized Controlled Trial (RCT) Comparing Green and Red Laser Photodynamic Therapy Using Low ose ALA for High Grade ysplasia in Barren's sophagus Chelliah R. Selvasekar, Marco R. Novelli, Sally Thorpe, Stephen G. Bown, Laurence B. Lovat Hlot Human Study of a Balloon-based Bipolar lectrode for Ablation of sophageal pithelium: Results in Subjects Prior to Planned sophagectomy Robert A. Ganz, Kenneth Batts ndoscopic Ablation of Barrett's Neoplasia. Rotterdam Results Jelle Haringsma, Peter. Siersema, rnst J. Kuipers Photodynamic Therapy in High Grade ysplasia in Barrett's Oesophagus Using 5 Amino-Laevulinic Acid Sensitization Finlay A. Macrae, Raje Rajesekaram, Robert Thomas, P. S. Bhathal ndoscopic Mucosal Resection for High-Grade ysplasia and Intramucosal Carcinoma Occurring in Barrett's sophagus Massimo Conio, Alessandro Repici, Renzo Cestari, Sabrina Blanchi, Guido Missale, Gabriella Lapertosa, Gianni Calandri, Rosangela Filiberti ASG Poster Session AM-5:00 PM SOPHAGUS W1550 Hall F Quality of Life After Palliative Treatment for sophageal Carcinoma: A Longitudinal Prospective Comparison Between Stent Placement and Single ose Brachytherapy Marjolein Y. V. Horns, Marie-Louise ssink-bot, Gerard J. J. M. Borsboom, wout W. Steyerberg, Peter. Siersema, for the utch SIRC study group w1551 w1552 w1553 w1554 w1555 w1556 W1557 w1558 W1559 w1560 w1561 w1562 ndoscopic Mucosal Resection Combined with Chemoradiotherapy for Superficial sophageal Squamous Cell Carcinoma Yuichi Shimizu, Mototsugu Kato, Junji Yamamoto, Souichi Nakagawa, Hiroyuki Tsukagoshi, Masahiro Fujita, Masao Hosokawa, Masahiro Asaka A Prospective, Randomized Study Comparing Two Self- xpanding Stents in the Palliation of Patients with ysphagia ue to Inoperable sophageal Cancer Massimo Conio, Alessandro Repici, Giorgio Battaglia, Giovanni e Pretis, Jean Francois emarquay, Max Bittinger, Helmut Messmann, Luigi Ghezzo, Sabrina Blanchi, Rita Conigliaro, Lnigi Gianffate, Michele Togni. Gianni Calandri, Rosangela Filiberti Role of Positron mission Tomography (PT) in a Muhimodality Staging Protocol with ndoscopic Ultrasound (US) and Computed Tomography (CT) fur sophageal Cancer Peter Stanko, eepak Gopal, Terrence Frick, Tracer \\ci~'] Patrick Pfau High Intensity Biopsy / High Frequency Uhrasound Probe Protocol May Accurately Identify BarreWs Patients Who Are Candidates For Local Ablative Therapy uke H. Nguyen, Sandeep Lahoti, Chris erbi, ndoscopic Mucosal Resection for sophageal Cancel Using MR-Tube (Control of the Size of Resected Mucosa and Preventing Perforation) Takashi Ogata Outcome of 138 Patients with arly Gastro-esophageal Cancer: Surgical vs. ndoscopic Resection Rohit Bhave, Vanessa Shami, Charles ye, Kerry Collier, Irving Waxman, William R. Brugge Implantation of a Self-expanding Plastic sophageal Stent (Polyflex Stem) - xperience in 39 patients Klaus Radecke, Guido Gerken, Ulrich Treichel sophageal Stents with Anti-Reflux Valve for Tumors Involving the istal sophagus and Gastric Cardia: A Randomized Trial Marjolein Y. V. Horns, Peter J. Wahab, rnst J. Kuipers, wout W. Steyerberg, Tim A. Grool, Jelle Haringsma, Peter. Siersema ndoscopic Mucosal Resection for Superficial sophageal Neoplastic Lesion: Comparison Between Macroscopic, Histological and Follow-up Results Thierry Ponchon, Mihai Ciocirlan, Jean-Christophe Saurin, Bertrand Napoleon, Christine Lefort, Jean Christophe Souquet, Bertrand Pujol, Annick Chavaillon Oesophageal Squamous Cell Carcinoma Screening Among High-Risk Patients: National Prospective Study of the French igestive ndoscopy Society (SF) Johann ubuc, Jean-Amaud Seyrig, Jean-Pierre Barbier, Thierry Barrioz, Rene Laugier, Guy Boulay, enis Grasset, enis Sautereau, an Grigoresco, Joel Butel, Jean-Louis Legoux, Thierry Ponchon Comparison of 3 Types of Covered Metal Stents for the Palliation of Malignant ysphagia: Results from the Ludwigshafen sophageal Cancer Register Axel ickhoff, Mathias Knoll, Ralf Jakobs, Uwe Weickert, Jens C. ickhoff, Juergen F. Riemann Palliation of Malignant ysphagia and Fistulae with Self xpanding Metal Stems Mike Bismar, Firas Alkassab, Jaffer A. Ajani, Patrick M. Lynch, William A. Ross P-273

80 POSTR SSSIONS--CLINICAL SCINC W N S A Y MAY 19 W1563 W1564 W1565 W1566 W1567 W1568 W1569 W1570 W1571 Tumor Related Factors Influencing the Accuracy of ndoscopic Ultrasound in Cancer of the sophagus and the Gastro-esophageal Junction Henderik L. Van Westreenen, Pierre A. M. Heeren, Hendrik M. van ullemen, John T. H. M. Plukker ndoscopic Resection of Superficial sophageal Squamous-Cell Carcinomas: Western xperience Oliver Pech, Liebwin Gossner, Andrea May, Manfred Stolte, Christian ll Successful n-bloc Resection of Large Superficial sophageal Cancer Using Sodium Hyaluronate and Small-Caliber-Tip Transparent Hood Makoto Nishimura, Hironori Yamamoto, Hiroto Kita, Keijiro Sunada, Kazunobu Hanatuka, Hiroshi Kawata, Kenichi Ido, Kentaro Sugano An Unusual Presentation of a Giant Fibrovascular Polyp and Review of the xperience at the Mayo Clinic, Rochester, MN: A Case Series Jonathan Gonenne, Susan C. Abraham, Kenneth K. Wang, Carlton W. Thomas, Gianrico Farrugia, Jonathan Clain, Paul J. Limburg Long Term Results of PT for arly Neoplasia in Barrett's sophagus Oliver Pech, Liebwin Gossner, Andrea. May, Manfred Stolte, Christian ll The Synergistic Use of Argon Plasma Coagulation (APC) and Self-xpanding Metallic Stents (SMS) for the Palliation of Malignant ysphagia Wing-Kin Syn, Iqbal Khan, Minesh Patel, Adrian Parnell, Michael P. Skander, Monzur M. Ahmed Computer-Aided iagnosis of Superficial Type arly sophageal Cancer by Image Processing on Ordinary ndoscopic Pictures Tatsuya Mikami, Yoshihiro Sasaki, Shinsaku Fukuda, Rynkichi Hada, Akihiro Munakata Treatment of arly Upper Gastrointestinal Tumors Using Photodynamic Therapy Mark Zammit, Grant Fullarton Wide ndoscopic Mucosal Resection in sophagus Using Modified Needle Knife: Porcine Model xperiment Shiro Urayama, Jason U Umphress W1575 W1576 W1577 W1578 W1579 W1580 W1581 W1582 W1583 W1584 Colorectal Neoplasia in Veterans Is Associated with Barrett's sophagus but Not with Use of Proton-Pump Inhibitors (PPIs) or Aspirin/NSAIs Peter. Siersema, Stanley Yu, Peyman Sahbaie, Peter Simpson, wout W. Steyerberg, rnst J. Kuipers, George Triadafilopoulos The Prevalence of Hiatal Hernia Is the Same in very Age Group - In Young and Old Alike. Part 2 in a Series: The Origins of GR Stephen J. Sontag, Thomas Schnell, Jack Leya Barrett's sophagus in Blacks and Hispanics: A Real Challenge to the "Acquired" Theory of evelopment. Part 4 in a Series: The Origins of GR Stephen J. Sontag, Thomas Schnell, Jack Leya, Greg Chejfec Primary Care Physician (PCP) Attitudes Towards Unsedated ndoscopy (U) and Screening Practices for Barrett's sophagus (B): A Survey Study Ashley L. Faulx, Vikram Boolchand, Ananya as, Stephen Zyzanski, Gerard Isenberg, Gregory Cooper, Michael V. Sivak Jr., Amitabh Chak Is sophagoscopy Alone Sufficient for Patients with Reflux Symptoms? - Final Results Stephan M. Wildi, Tammy F. Glenn, Robert F. Woolson, Wei Wang, Robert H. Hawes, Michael B. Wallace Improved Routine etection of Barrett's sophagus Jean-Francois Rey, Konstantin Kuznetsov High Resolution Chromoendoscopy with Acetic Acid for the etection of Intestinal Metaplasia and arly Neoplasia in Barretts sophagus - a Prospective Trial Liebwin Gossner, Andrea May, Manfred Stoke, Christian ll The etection of Barrett's sophagus After ndoscopic Healing of rosive sophagitis Sameh Hanna, Allan Weston, Sharad Mathur, Matthew Hall, Robert J. Schrnitz, Rachel Cherian, Prateek Sharma Unrecognized Barrett's sophagus in Patients with rosive sophagitis Unveiled by Methylene Blue Chromoendoscopy Stephen N. Wong, Jose. Sollano Jr., Melchor M. Chan, Rolando Lopez, Johnny T. Go, Victoriano Y. Lim, Carrnelita. alupang, Ramon. Carpio Barrett's sophagus Screening: Is Age Really a Factor? Tammy Glenn, Carolyn Reed, Robert H. Hawes ASG Poster Session AM-5:00 PM Hall F SOPHAGUS W1572 A Prospective ndoscopic Study of Cardial Intestinal Metaplasia Muls Vinciane ASG Poster Session AM-5:00 PM SOPHAGUS W1573 W1574 Hall F Prevalence of Barrett's sophagus (B) in Asymptomatic Women Lauren B. Gerson, Subhas Banerjee, George Triadafgilopoulos Simultaneous Screening for Barrett's and Colorectal Cancer Gareth ulai, ennis M. Jensen, M. Saad, I. Mawas, J. Yu, L. Fontana W1585 W1586 W1587 W1588 W1589 W1590 NA Ploidy Analysis with Image Cytometry on Barrett's sophagus-related ysplasia and sophageal Adenocarcinoma Chenggong Yu, Qin Huang, Michael Klein, Raj K. Goyal Temporal Change in Barrett's sophagus Segment Length (BSL) uring Prospective Surveillance Leilani M. Sharpe, Xiaohong Li, avid Cowan, Brian J. Reid, ouglas S. Levine, Kamran Aynb, Patricia L. Blount Capsule ndoscopy: Can It Replace Upper ndoscopy to Screen for Barrett's? Felice Schnoll-Sussman, Adam B. Hernandez, Toral Shah Ultra-Jumbo Biopsies for Sampling Barrett sophagus in Surveillance and Post-Ablation Therapy Patients rew Schembre, Marla Fenske The Prevalence of Barrett's sophagus in Native Americans Verapan Vongthavaravat, Madhavi Rudraraju, Richard F. Harty Narrow Band Imaging ndoscopy for the etection of ysplastic and Non ysplastic Barrett's sophagus Prateek Sharma, Sharad Mathur, Anita ixon, Allan Weston P-274

81 v POSTR SSSIONS~CLINICAL SCINC W1591 W1592 W1593 W1594 W1595 Acetic Acid Magnification Chromondoscopy etects All Focal High Grade ysplasia in Barrett's sophagus Michael Miros, avid Cohn, Neal Walker Acetic Acid Chromoendoscopy Improved etection of Islands of Barrett's pithelium in GR Patients H. K. Kim, S. H. Park, J. K. Kim, Kyu-Young Choi, In-Sik Chung, K. W. Chung, H. S. Sun Should We Biopsy an Irregular Z-Line? The Yield of Biopsy to iagnose Short-Segment Barrett's sophagus awn. Ferguson, Kenneth R. evault, Herbert C. Wolf sen uration of Heartburn Is the Only Symptom Characteristic That istinguishes Between Patients with Long Segment (LSB) and Those with Short Segment Barrett's sophagus (SSB) Jimmy Kim, Lisa Camargo, Richard. Sampliner, Harinder S. Garewal, Ronnie Fass Barrett's ysplasia and Mucosal Carcinoma Patients Referred for Photodynamic Therapy --o They Come from Surveillance Programs? Herbert C. Wolfsen, Lois L. Hemminger, Kenneth R. evault ASG Poster Session AM-5:00 PM LOWR GI BLING W1596 W1597 W1598 W1599 W1600 W1601 W1602 Hall F oes Instillation of Peppermint Oil Solution in the Cecum Facilitate Terminal Ileal Intubation? A Prospective, Randomized, ouble-blind Study Madhusudhan R. Sanaka,. Roy Ferguson, Annette Kyprianou, Hemangi Kale, Kevin. Mullen, Saeid Amini ndoscopic Balloon ilation Is Safe and ffective in Patients with Ileal Pouch Strictures Bo Sben, Bret Lashner, Aaron Brzezinski, Feza Remzi, Jane Bast, Marlene Bambrick, Victor Fazio Is a Recent pisode of iverticulitis an Acceptable Indication for Colonoscopy? Pascale Anglade, aniel Gelrud, Adriana Milillo, aniel Mishkin Sublingual Hyoscyamine Facilitates Colonoscopy and ecreases Colon Motility: A Randomized, ouble Blinded, Placebo Controlled Trial Louis A. Chaptini, ileen M. Janec, Gregory I. Seltzer, Steven R. Peikin, Adam B. lfant Application of ouble-balloon ndoscopy for Technically ifficult Cases with Conventional Colonoscopy Tomonori Yano, Hironori Yamamoto, Hiroto Kita, Keijiro Sunada, Yoshikazu Hayashi, Hiroyuki Sato, Michiko Iwamoto, Yutaka Sekine, Tomohiko Miyata, Akiko Kuno, Takaaki Iwaki, Yoshiyuki Kawamura, Hironari Ajibe, Kenichi Ido, Kentaro Sugano Finger-assisted ndorectopexy: escription and Prospective Study of a Method for the ndoscopic Treatment of Stage 3 Internal Hemorrhoids and Prolapse Z. A. Saeed Reduced Volume Lavage Solution Versus Sodium Phosphate Tablet Preparation for Colonoscopy Juan A. Guerrero, Charles. Brady III W1603 W1604 W1605 W1606 W1607 W1608 W1609 w1610 W1611 W1612 Correlation of Colonic Thickening on Computed Tomography (CT) with Colonoscopy Shardul A. Nanavati, Rassa Shahidzadeh, Hashem l-scrag, Gulchin A. rgun MR of Large Sessile Colorectal Polyps: Are Complications and Recurrences Related to the Technique? Pietro Familiari, Lucio Petruzziello, Monica Pandolfi, Armando Gabbrielli, Gianluca Spera, Andrea Tringali, Cristiano Spada, Guido Costamagna Open Access Colonoscopy: Appropriateness of Indication and iagnostic Yield According to ASG 2000 Guidelines Iqbal Siddique, Krishna Molnan, AnjLun Mcmon. Iruad Hasan Colonoscopic iagnosis of Mncocele of the Appendix Simon A. Zanati, Norman. Marcon, Gregor) B Hab~:l. Gabor Kandel, Paul Kortan Reduced Volume Versus Standard Volume Lavage Solution for Colonoscopy Juan A. Guerrero, Charles. Brady iii, John alton ndoscopic Treatment of Anorectal Condylamata Acuminata Using Argon Plasma Coagulation Georgios Alexandrakis, Periklis Apoqok,pou/o>. loanni, '~ Papanikolaou, Marios Christoforou, Gemsimo> Markato> Panagiotis Skordilis, Alexandra Alogari, Peter Gab:id, Nikolaos Kalantzis The ffect of Prior Abdominal and Pelvic Surgery on Colonoscopy Completion and Insertion Time Sang Kil Lee, Chang Hwan Choi, Tae I1 Kim, Won Ho Kim Routine Terminal Ileal Intubation at Colonoscopy Increases iagnostic Yield Alan Coss, Abdur R. Aftab, erek Power, Frank. Murray, Stephen. Patchett Usefulness of ndoscopic xamination for Japanese Patients eveloping Intestinal amage After Bone Marrow Transplantation Ai Machida Technical Modification of the ouble-balloon ndoscopy to Access to the Proximal Side of the Stenosis in the istal Colon Tomonori Yano, Hironori Yamamoto, Hiroto Kita, Makoto Nishimura, Keijiro Sunada, Yoshikazu Hayashi, Hiroyuki Sato, Michiko Iwamoto, Yutaka Sekine, Tomohiko Miyata, Akiko Kuno, Takaaki Iwaki, Yoshiyuki Kawamura, Hironari Ajibe, Kenichi Ido, Kentaro Sugano ASG Poster Session AM-5:00 PM LOWR GI BLING W1613 W1614 Hall F Is Magnifying Colonoscopy ffective to Prevent Post- MR Bleeding? Kazuko Beppu, Takeshi Terai, Wensheng Pan, Satoshi Abe, Naoto Sakamoto, Osamu Kobayashi, Hiroto Miwa, Toshifumi Ohkusa, Tatsuo Ogihara, Nobuhiro Sato A Prospective Comparison of Colonoscopy and Flexible Sigmoidoscopy for the valuation of Young Adults with Rectal Bleeding: Preliminary Results Ryan. Madanick, Jason A. Slate, Brian S. ooreck, Rachel N. Koppelman, Jeffrey B. Raskin P-275

82 POSTR SSSIONS--CLINICAL SCINC I W N S A Y MAY 19 W1615 W1616 W1617 W1618 W1619 W1620 W1621 W1622 Lower Gastrointestinal Bleeding ue to Colonic ieulafoy Lesions: Cumulative Incidence and Treatment Outcomes Scott W. Grisolano, Jack I. Ramage Jr., arrell S. Pardi, Bret T. Petersen Argon Plasma Coagulation in the Prevention of Recurrent Bleeding from Colonic Angiodysplasias Jorge A. Olmos, Mariano Marcolongo, Valeria Pogorelsky, Leandro Herrera, Jorge avolos Bleeding from Rectal Varices in Patients with Liver Cirrhosis - an Ominous vent Max Bittinger, Andreas Probst, Thomas berl, Wemer Schmidbaur, Juergen Bamert, Gertrud Jechart, Helmut Messmann Clinical Factors Are Predictive of Bleeding Location in Severe Hematochezia Arash Zarimani, ennis Jensen, Vichuda Lousuebsakul, Jeff Gombein, Mary Jensen Hyperbaric Oxygen Therapy for Chronic Radiation nteritis Gary T. Marshall, Richard C. Thirlby, James. Bredfeldt, Neff B. Hampson Usefulness of Angiography in Patients with Undiagnosed Lower Gastrointestinal Bleeding Carmen Abadia, Ana Adet, Saperas steve, Faust Feu, J.R. Armengol, Juan Malagelada, Pique Jose M The Right and Left Conundrum: Colonoscopy or Flexible Sigmoidoscopy for the Investigation of Isolated Rectal Bleeding (IRB) Maeve M. Skelly, Ramesh Arasaradnam, Mark T. onnelly Comparison of Safety and Outcome Between Two Argon Plasma Coagulation Settings for Radiation Proctopathy in Patients with Prostate Cancer Richard S. Kwon, Clair Beard, Anthony V. 'Amico, avid L. Carr-Locke ASG Poster Session AM-5:00 PM LOWR GI BLING w1623 w1624 W1625 W1626 W1627 Hall F fficacy and ffective ndoscopic Findings of Granulocyte and Monocyte Absorption Apheresis (GCAP) and Leukocytapheresis (LCAP) Therapy in Patients with Refractory Active Ulcerative Colitis (UC) Kenji Watanabe, Takayuki Matsumoto, Yoshio Jinno, Shiro Nakarnura, Nobuhide Oshitani, Kazuhide Higuchi, Tetsuo Arakawa iagnosing Crohn's isease (C) with Capsule ndoscopy (C): Careful Consideration Required avendra Ramkumar, Robert Summers Rifaximin as Short-Term_"B~ ~rapy" in Mild- ModerateLef~l~e~ls~ to 5 ASA G~ai~f~,lIV~'~p~azzo, M.. Bazuro, M. F~ I~G~ Pt'pp~a Is the Mucosal Inflammation in Ulcerative Colitis Assessed qually on Videos and Photos? Thomas de Lange, Stig Larsen, Lars Aabakken Composition of Hdl Is ependent on the Inflammatory State uring Crohn's isease R.. L. Hezemans Sr., Johannes H. M. Levels, aan W. Hommes, Sander J. van eventer, rik de Groot W1628 Going the xtra Inch: Quantifying the Benefits of Terminal Ileal Intubation James B. Canavan, laine W. Kay, Stephen. Patchett, Frank. Murray ASG Poster Session AM-5:00 PM Hall F LOWR GI BLING W1629 W1630 W1631 W1632 w1633 W1634 W1635 W1636 W1637 W1638 W1639 A Novel ndoscopic Submucosal issection Method Using the Hook Knife for Large Colorectal Tumors Kinichi Hotta, Tsuneo Oyama, Yoshinori Miyata Impact of Facilitated Follow-Up on Adherence to Surveillance (or Secondary Screening) Guidelines for Colorectal Cancer Ganesh R. Veerappan, Nizar Mukhtar, Corinne Maydonovitch, Brian P. Mulhall I Once Caught a Fish This Big: ndoscopists' stimate of Polyp Size avid H. McMillen, John M. Inadomi oes ndoscopic Resection Increase the Risk of Lymph Node Metastases? Yutaka Saito, Takahisa Matsuda, aizo Saito, Takahiro Fujii, Fabian mura, Yasushi Sano Accuracy of FG-PT in the etection of Colonic Neoplasms Shai Friedland, Roy M. Soetikno, Marie Carlisle, Alan Taur, Tonya Kolodziejski, George Segall A Comparision of ark Lumen MR Colonography and Conventional Colonoscopy for the etection of Colorectal Polyps irk Hartmann, Boris Bassler, ieter Schilling, Barbara Tiziani, Anika Rosenbaum, Herrmann Breer, Guenter Layer, Juergen F. Riemann Novel iagnostic Method for Colorectal Mucosal Lesion Using a Narrow Band Imaging System Kuwamura Hikaru, Machida Hirohisa, Itou Hiroaki, Sano Yasushi, Taku Keisei, lwasaki Jyunko, Yoshida Siei Prospective Comparison of CT Colonography and Conventional Colonoscopy for etection of Colorectal Neoplasms in aily Clinical Practice Using Second-Look Colonscopy in Cases with iscrepant Results Peter Netzer, Hanno Hoppe, Cristiana Quattropani, Adrian Spreng, Hans-Peter inkel arly and Late Outcome of Patients with Obstructing Colorectal Cancer Treated by Stenting and lective Surgery: A Comparison with mergency Surgery and Patients Operated Without Obstructive Symptoms Alessandro Repici, Massimo Conio, Stefania Caronna, Claudio e Angelis, Cloe alla Costa, Mar'to Morino, Alberto Foco, Paolo Mioli, Luca Petruzzelli, Mario Rizzetto, Silvia Martini, Giorgio Saracco Cost-effectiveness of Magnifying and Conventional Colonoscopy Takahisa Matsuda, Yutaka Saito, Takahiro Kozu, aizo Saito "Invasive Pattern" isclosed with Magnifying Chromo- ndoscopy Is an Indication for Surgical Treatment of Sessile Colorectal Polypoid and Non-Polypoid Lesions Maria Antonia Bianco, Gianluca Rotondano, Maria Lucia Garofano, Riccardo Marmo, Roberto Piscopo, Livio Cipolletta P-276

83 POSTR SSSIONSmCLINICAL SCINC W1640 ~1641 W1642 iagnosis and Treatment of T1 Colorectal Cancer Hiroshi Kashida, Tsukasa Takeuchi, Toshinori Kurahashi, Norio Fukami, Fuyuhiko Yamamura, Kazuo Ohtsuka, Shin- i Kudo A Prospective, Randomized Comparison of Bipolar lectrocoagulation Versus Conventional Monopolar Hot Biopsy Forceps in the ndoscopic Treatment of iminutive Rectal Adenomas Gregorios A. Paspatis, mmanouil Vardas, Nikolaos Papanikolaou, mmanouil Zois Clinical and Cost fficacy of a Weekend Colon Cancer Screening Colonoscopy Clinic Courtney Barancin, Adnan Said, Terrence Frick, ric Gaumnitz, eepak Gopal, Russell Jacoby, Michael Lucey, Mark Reichelderfer, John B. Wyman, Patrick Pfau W1654 W1655 W1656 Older Age and Proximal Location Are the Risk Factors for Metachronous Advanced Neoplasms After Colorectal Polypectomy: Analysis of Cases with Long-term Colonoscopic Surveillance Makoto Okamoto, Yutaka Yamaji, Hirotsugu Watabe, Tsuneo Ikenoue, Gouichi Togo, Shintaro Kondo, Miki Ota, Haruhiko Yoshida, Takao Kawabe, Masao Omata Comparison Between High-Resolution Colonoscopy with and Without Chromoendoscopy and Histological Findings in iminutive Lesions of Rectosigmoid arius Apel, Ralf Jakobs, ieter Schilling, Uwe Weickert, Jochen Teichmann, Juergen F. Riemann Retrospective Analysis of Patients iagnosed with Colorectal Cancer Above the Age of 75 by Colonoscopy Suneetha uttala, Omar Al-Subee, Murray hrinprcis W1643 W1644 Colonoscopic Surveillance of Adenomatous Polyps: A Survey of Primary Care Physicians Knowledge of Current Guidelines Gregory Olds, Pankaj Singh, Amitabh Chak, Gregory Cooper Racial Variation in Colon Pathology etected After a Positive Screening Flexible Sigmoidoscopy Fritz Francois, James Park, dmund J. Bini W1657 W1658 isparities in the Risk of Cancer of the Colon and Rectum Remaining Unstaged After iagnosis James C. HoNey, ugene Lengerich Risk of Post-Colon Polypectomy Bleeding, Including Aspirin Intake with iscontinuation Period of Two Weeks Shigeki Oka, Morio Takahashi. Hiroki Ichimura, Masafumi Kiumi, Hironobu Takada, Ha]ime Kuwayama W1645 W1646 Recommendations Following Screening Colonoscopy Limited by Inadequate Bowel Preparation Christine T. Bang, Christopher S. Lee, Shahzad lqbal, Albert. Min Colorectal Stenting: An ffective and Costsaving Therapy in Acute Leftsided Obstruction Res Jost, Rahel Jost, Marco ecurtins, ric Schoch, Brigitte Brunner, Christoph Zollikofer W1659 W1660 Association Between Serum Insulin Levels and Prevalent Colorectal Neoplasia in a Japanese Population Isao Yoshida, Ayako Suzuki, Toshlhide Okada ndoscopic Mucosal Resection of the Large and Sessile Colorectal Neoplasms. A Prospective Assessment of the fficacy and Safety Martin Bortlik, Milan Lukas, Stanislav Adamec, Tomas Krechler, Ales Novomy, Petra Chalupna, Ivo Horny W1647 Colorectal Stenting: An ffective Therapy in Acute Obstruction and Palliation Rahel Jost, Christoph Zollikofer, Marco ecurtins, ric Schoch, Brigitte Brunner, Res Jost W1661 The Role of Intraoperative Colonoscopy in Patients with Left Side Colon Cancer Obstruction Jun Hwan Kim, Byung Ik Jang, Tae Nyeun Kim, Moon Kwan Chung W1648 W1649 o Symptoms Affect Compliance in Colorectal Screening? Gunninder Soin, arren Smith, Mohammed Ballal, S. N. Selvachandran, avid Cade Relationship of Colon Adenomas to iet and xercise in Subjects at High-Risk of Colon Cancer Based on Family History Robert F. Wong, Amy L. alton, Jahn BarIow, Jennica rickson, Ken Boucher, Randall W. Burr W1662 W1663 A Study of Relationship of the Pit Pattern, the Capillary Vessel on the Surface of the Lesion and Pathological Features in Colorectal Neoplasm Yasushi Imai, Hiro-O Yamano, Masaru Nakazato, Satoshi Maeda, Hiro Matsushita Clinicopatholagical ifferences of Colorectal Cancer in Three Age Groups of a Japanese Population Takeshi Nakajima, Takahisa Matsuda, Yutaka Saito, aizo Saito, Masahiro Moriya W1650 W1651 W1652 W1653 Follow-up of Serrated Adenomatous Polyps: Synchronous and Metachronous Lesions Susan K. Chu, Stanley ea Incidence of Proximal Lesions in Patients with Occlusive Colorectal Cancer Nozomu Kobayashi, Yutaka Saito, Takahisa Matsuda, aizo Saitoh Incidence and Malignant Potential of Non-polypoid and Polypoid Colorectal Neoplasms at National Cancer Center, Tokyo Takahisa Matsuda, Yutaka Saito, Fabian mura, Takahiro Kozu, aizo Saito Self-expandable Metallic Stents Placement for Acute Obstruction in Colon Cancer: Technical and Clinical ffectiveness, Complications and Impact on Surgical Plan Management Mario A. Vitale, Giuseppe Villotti, Lucia 'Alba, Maria Assunta e Cesare, Stefano Frontespezi, Federico Iacopini, Giampaolo Iacopini W1664 W1665 W1666 W1667 Physician Recommendation Is the Most Important Factor for Acceptance of Postpolypectomy Surveillance arius Ape1, Christine Koch-Schultheiss, Juergen F. Riemann Colorectal Cancer Screening Program by Colonoscopy in 55-Yr-Old Subjects Chilovi Fausto, Bertozzo Andrea, Amplatz Stefano, Benvenuti Stefano, Comberlato Michele, Alberto de Guelmi, i Fede Francesco, Farris Piercarlo, Felder Martina, Grasso Tiziana, Hauer Susanne, Piazzi Lucia, Laura Zancanella Virtual Histology of Colorectal Lesions Using ndo- Cytoscopy System Keita Sasajima, Haruo Inoue, Shinei Kudo, Tsukasa Takeuti, HIroshi Kashida Can Magnification Chromo-Colonoscopy Predict the Histology of Colorectal Polyps More Accurately Than Conventional Colonoscopy? Kazutomo Togashi, Graham L. Radaford-Smith, avid G. Hewett, avid A. Whitaker, Georgia. Hume, Leo Francis, Mark N. Appleyard P-277

84 W N S A Y MAY 19 W1668 W1669 W1670 W1671 W1672 W1673 W1674 W1675 W1676 W1677 W1678 W1679 W1680 W1681 W1682 I I I Colon Polyp Receuurence: Predictors of arly evelopment of Significant Polyp Jin-Bae Kim, ong-soo Han, Jong-Pyo Kim, Hang-Lak Lee, Joo-Hyun Sohn, Joon-Soo Hahm ndoscopic iagnosis of Laterally Spreading Tumors in the Colorectum --A Treatment Consideration-- Toshio Uraoka, Yutaka Saito, Takahisa Matsuda, Akira mura, Nozomu Kobayashi, aizo Saito, Takahiro Fujii Importance of Hyperplastic Polyps and Adenomas 5mm or Less in iameter That Are etected by Screening Flexible Sigmoidoscopy James Park, Fritz Francois, dmund J. Bini Frequency of Hyperplastic Polyp-Like Morphology (Serrations) in Sporadic Large Bowel Adenomas Stefano Serra, Maha Guindi, Robert H. Riddeli Characterristics of Colorectal Cancer and Adenoma Observed in Surveillance Colonoscopy After ndoscopic Resection of All Neoplasms Tabuchi Masafumi ndoscopic Mucosal Resection - a Safe and ffective Management Tool fo r Benign and Malignant Colorectal Polyps Jainudeen K. A. Jameel, Stephen H. Pillinger, Peter Moncur, H. H. Tsai, Graeme S. uthie Colorectal Cancer Subsite istribution: Time-Trends and ffects of Aging in a Single Center Aqib Sultan, Angel Nickolov, Randall Brand, Hemant K. Roy Pit Pattern iagnosis by Magnifying ndoscopy efines Neoplastic Changes of the Colonic pitherial Tumors Yasushi Fukutomi ndoscopic Mucosal Resection for Advanced Non- Polypoid Colorectal Adenoma and arly Stage Carcinoma Livio Cipolletta, Maria Antonia Bianco, Gianluca Rotondano, Riccardo Marmo, Antonio Prisco, Teresa de Simone', Roberto Piscop0 Clinical Features of Ten Patients with Cowden isease Marianne Mozer, Terris Benoit, Grandjouan Sophie, Chaussade Stanislas Hexaminolevulinate- Induced Fluorescence ndoscopy in Patients with Rectal Adenoma and Cancer sther ndlicher, Cornelia Gelbmann, Ruth Knuechel, Alois Fuerst, Roll-Marcus Szeimies, Stefan Goelder, Juergen Schoelmerich, Helmut Messmann Polyp Surveillance - xperience from a Single Gastrointestinal Unit Ramona M. Mc Loughlin, S. S. Shaji, Asghar Qasim, H. J. O'Connor, Martin Buckley; Colm O'Morain Treatment of Large Colorectal Polyps : ndoscopic Versus Surgical Resection enis Bernard, Ledit Alain, Towa Olaf, Chiappa Pascale, Bottlaender Jacques, Peter Andre, Anne Marie Weiss, Maguin enis Pitfall of Immunological Fecal Occult Blood Test; a Comparison with Total Colonoscopy Tamiya Morikawa, Jun Kato, Yutaka Yamaji, Ryoichi Wada, Takeshi Kokubo, Tom Mitsushima, Yasushi Shiratori ndoscopic Implantation of Self-expanding Metal Stents (SMS) in Acute Malignant Colonic Obstruction Max Bittinger, Wemer Schmidbaur, Reinhard Scheubel, Thomas berl, Reinhard Fleischmann, Juergen Bamert, Helmut Messmann POSTR SSSIONSmCLINICAL SCINC W1683 W1684 W1685 Performance and Compliance of lmmunochemical vs.guaiac Faecal Occult Blood Test in Screening for Colorectal Cancer in a Chinese Population L. L. Lira, Khek-Yu Ho, T. Z. Ong, K. G. Yeoh Correlation Between Mucosal Crypt Patterns Using Magnifying Colonoscopy and Mucosal ye Spraying and Histological Findings of Colorectal Lesions Giovanni. e Palma, Maria Rega, Paola Ciamarra, Francesco Patrone, Luigi Mastantuono, Giovanni Persico Patient Acceptance of MR-Colonography and Conventional Colonoscopy: - Preliminary ata of a Propsective Comparative Study in Patients with Suspected Colorectal isease ieter Schilling, irk Hartmann, Barbara Tiziani, Boris Bassler, Guenter Layer, Juergen Riemann ASG Poster Session AM-5:00 PM Hall F LOWR G! BLING W1686 W1687 The Frequency of Post-infectious IBS (PI-IBS) in Patients with Acute iarrhea and the Risk Factors for PI-IBS of Special Reference to the Colonoscopic Findings Jong-Soo Lee, Sung-Ae Jung, Ki-Nam Shim, Seong-un Kim, Moon Sun Yeom, Han Hyo Lee, Jun Sik Nam, Hye- Kyung Jung, Sun Young Yi, oe-young Kim, Kwon Yoo, II- Hwan Moon ndoscopic and Clinicopathological Features of Gastrointestinal Involvement in Churg-Strauss Syndrome Kunihiko Aoyagi, Chifumi Yamamoto, Kazunori Maeda, Koichi guchi, Isamu Morita, Shuji Tada, Takayuki Matsumoto, Shotaro Sakisaka P-278

85 POSTR SSSIONS~COMBIN SCINC COMBIN SCINC Authors are required to be present during the Poster Session from 12:00-2:00 pro. Those posters identified as W Posters of istinction have received review scores that place them within the top 10% of all posters. We encourage you to make them a priority as you visit the poster session. AM-5:00 PM Hall F Sponsored by: AGA; Liver and Biliary LIVR TRANSPLANTATION W1688 W1689 W1690 W1691 W1692 W1693 W1694 W1695 New Prognosis Prediction System for Liver Transplantation in Patients with Fulminant Hepatic Failure Miyake Yasuhiro, Sakaguchi Kohsaku, Iwasaki Yoshiaki, Shiratori Yasushi Are Genetic Polymorphisms in Orthotropic Liver Transplant Recipients Responsible for levated Serum Homocysteine? Bora Akoglu, Petra Kindl, Nicole Weber, Joerg Trojan, Wolfgang F. Caspary, ominik Faust Asymmetrical imethylarginine; a Possible Future Marker for Acute Liver Allograft Rejection? Michiel P. C. Siroen, Michiel C. Warle, Tom Teerlink, Robert J. Nijveldt, Hugo W. Tilanus, Herold J. Metselaar, rnst J. Kuipers, Joost R. M. van der Sijp, Sybren Meijer, Ben van der Hoven, Paul A. M. van Leeuwen Predictors of Weight Change Following Liver Transplantation Laith H. Jamil, Michael R. Charlton, Sara R. icecco, Nickie M. Franciscozfller, Walter K. Kremers, John J. Poterucha, Charles B. Rosen When Should xtended onor Criteria Grafts Be Considered For Liver Transplant Under The ML System? A ecision Analysis Manish G. Amin, Michael P. Wolf, John A. Tenbrook Jr., Richard B. Freeman Jr., Steve J. Cheng, aniel S..Pratt, John B. Wong "Crane-neck" Shaped Biliary Stricture as an Important Complication after Right-Lobe Living-onor Liver Transplantation with uct-to-uct Biliary Reconstruction Takanobu Yoshimoto, Shujiro Yazumi, Hiroshi Hisatsune, Shinsuke Tada, Masanori Asada, Kazunori Hasegawa, Yoji Maetani, Hiroto gawa, Koichi Tanaka, Tsutomu Chiba ndoscopic Management of Biliary Strictures After uctto-uct Biliary Reconstruction in Right-Lobe Living- onor Liver Transplantation; The Second Report of the "Inside-Stent". Shujiro Yazumi, Takanobu Yoshimoto, Hiroshi Hisatsune, Kazunori Hasegawa, Masanori Asada, Akiyoshi Nishio, Hiroto gawa, Koichi Tanaka, Tsutomu Chiba Magnetic Resonance Cholangiopancreatography for the Noninvasive valuation of Liver Transplant Patients with Suspected Biliary Strictures: A Prospective ouble- Blind Study Paul S. Chard, Aliya Qayyum, Sinda Mein, Fernando Velayos, Jeffrey Halldorson, John Roberts, James W. Ostroff W1696 W1697 W1698 arly Biliary Complications Following Liver Transplantation Are Amenable to ndoscopic Intervention Scott W. Biggins, Ryan McTaggart, lizabeth Cruz, Sandy Feng, Robert Kerlan, John P. Roberts, Norah Terrault, James W. Ostroff Activity and Neoplastic Potential of Ulcerative Colitis After Orthotopic Liver Transplantation for Primary Sclerosing Cholangitis Pavel rastich, Miroslav Ryska, Pavel Trunecka, Jan Martinek, Julius Spicak ndoscopic Therapy for Biliary Complications Following Orthotopic Liver Transplantation with Choledochocholedochostomy Anastomosis All Fazel, Hen U Chiu, Shea Ross, Consuclo Soldc\ ~/, P:,,: Koorosh MoezArdalan, Christopher Forsmark AM-5:00 PM N~dt f Morktl Co~lv~'t~tio~l </c<,'~ Sponsored by: Gastrointestinal Oncology SOPHAGAL CANCR: COMBIN Genomic Profiling Suggests That Barretta's sophagus Is W1699 More Similar to sophageal Adenocarcinoma Than to Normal sophagus Suna Wang, Jing Yin, Yan Xu, Yuriko Mori, Fumiaki Sato, Andreea Olaru, lena eacu, Anca Sterian, Karsten Schulmann, John M. Abraham, Bruce. Greenwald, Stephen J. Meltzer Novel xpression of Vascular Cell Adhesion Molecule-1 W1700 (VCAM-1) in Human Squamous sophageal pithelium - Pathophysiological Implications Jan Heidemann, Christian Maaser, Andreas Lugering, Thomas W. Spahn, Klaus P. Zimmer, Hermann Herbst, Wolfram omschke, Parvaneh Rafiee, avid G. Binion, Torsten Kucharzik Molecular Genotyping of sophageal Neoplasms Pre and W1701 Post Photodynamic Therapy Alyssa M. Krasinskas, Rehka Pal, lizaburo Sasatomi, Laura Niehouse, Patricia A. Swalsky, Sydney. Finkelstein GFR Inhibition in Patients with sophageal Cancer: W1702 Assessment of Reduced Cellular Proliferation and Gene xpression Analysis by Microarray. Mark R. Anderson, Jolanta Obszynska, avid Ferry, Janusz Jankowski Gene xpression Profiling Analysis Reveals Calgranulin W1703 A and B as Potential Novel Tumor Markers for Highgrade ysplasia in Barrett's sophagus orine A. Bax, Jelle Haringsma, Herman van ekken, Peter. Siersema, rnst J. Kuipers, Johannes G. Kusters Real-Time RT-PCR Cluster Analysis from a 2-Gene W1704 Marker Panel Allows for Potential Molecular iagnosis of sophageal Adenocarcinoma Michael Mitas, Kaidi Mikhitarian, avid H. Robbins, Angela Collier, Peter King, avid Cole, William. Gillanders, Brenda Hoffman ffects of Aspirin and the Natural Cox-2 Inhibitor W1705 Quercetin on the evelopment of sophageal Adenocarcinoma in a Rat Model Andrew Hindmarsh, dward Cheong, Virginia Sams, Lazlo Igali, Joanne oleman, Nigel Belshaw, lizabeth K. Lund, Michael Rhodes, Ian T. Johnson ~'T-I 77-- =-~ enotes W Poster of istinction P-279

86 POSTR SSSIONS--COMBIN SCINC W N S A Y MAY 19 W W1707 W1708 W1709 w1710 W1711 W1712 W1713 W1714 Cyclin 1 Polymorphism (G870A) and Risk for Gastroesophageal Reflux, Barrett's sophagus and W1717 sophageal Adenocarcinoma: A Case-Control Study Alan G. Casson, Zuoyu Zheng, Susan vans, Paul Veugelers, Geoffrey Porter, uane Guernsey PolymorphIsm in xon 4 of the p53 Gene in Barrett Metaplasia: Increased Frequency of the Pro/Pro W1718 Genotype in Hispanics Mamoun Younes, Baomin Liu, Jiang Wang, Attila rtan, Gulchin rgun, Ray Verm, Margaret Bridges, Karen Woods, Frank Meriano, Carl Schmulen, Ronald Colman, ean Solcher, Craig Johnson, Alberto Barroso, Cecilia Fenoglio- Preiser W1719 Cell Cycle Phase istribution in Neoplastic Progression of Barrett'S Oesophagus Pierre Lao-Sirieix, Rebecca J. Brais, Nicholas Coleman, W1720 Rebecca Fitzgerald The Oesophageal Lumen Has the Chemical Conditions for Generating Carcinogenic N-Nitroso Compounds Hisaharu Suzuki, Kenneth Mclroy, Gordon Scobie, Valerie W1721 Fyfe, Kenneth. L. McColl Gene xpression in arly Barretts sophagus Related Cancers Kenneth K. Wang, Navtej Buttar, Louis-Michel Wong Kee W1722 Song, Marlys Anderson, Cassie emars, Lori Lutzke, Sarah Papenfuss Curcumin, a Natural Agent Found in Turmeric, Induces Growth Inhibition of Barrett's Associated sophageal Adenocarcinoma Cells Mihir S. Wagh, Howard Y. Chang, Hemanta Koley, Masood A. Shammas, Raj K. Goyal MUC4 Is Increased in High-grade ysplasia in Barrett's sophagus and Is Associated with a Pro-apoptotic Bax/ Bcl-2 Ratio orine A. Bax, Jelle Haringsma, Peter. Siersema, Paul Blok, Herman van ekken, Alexandra W. C. inerhand, rnst J. Kuipers, Johannes G. Kusters W1723 ifi Association of lnterleukin 1 Beta Gene-511 Single 5 Nucleotide Polymorphism with sophageal Cancer Kaukab Azim, ermot Kelleher, John V. Reynolds W1724 Human Papillomavirus-16 and -18 NA and pstein-bar Virus NA in sophageal Squamous Cell Carcinoma Tahereh Ghaziani, Hossein Sendi, Arash Javeri, Mohammadreza Agah, Babak Noorinayer, Omid drisian, SeyedJavad Mirhassani-Moghadam, Saeed Samiei, Fatemehsadat steghamat, Mohammad Reza Reza Zali AM-5:00 PM Hall F Sponsored by: Gastrointestinal Oncology W1725 PANCRATIC CANCR: COMBIN U In situ emonstration of Reduced Monocyte Migration W1715 W1716 in Mouse Pancreatic Cancer by Intravital Microscope Yoshikazu Tsuzuki, Jyunichi Miyazaki, Koji Matsuzaki, aigo Onodera, Shinichiro Yoshimitsu, Ryota Hokari, Atsushi Kawaguchi, Shigeaki Nagao, Kazuro ltoh, Soichiro Miura Implication of Chromosome 18 Abnormalities in the Progress of Pancreatic Cancer Makoto Sunamura, Liviu P. Lefter, Rina Morita, Akira Horii, Torn Furukawa, Shinichi gawa, Seiki Matsuno Z1839 (Iressa), a Selective pidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Inhibits Pancreatic Cancer Cell Growth, Invasion, and Colony Formation Helmut Friess, Junsheng Li, Markus W. Buchler, Murray Korc, Jorg Kleeff Human Insulin-Like Growth Factor Binding Protein 3 (IGFBP-3) Gene Transfer ramatically Inhibits the Growth of stablished Colonic Tumors in a Murine Model Irena Kirman, Natalia Pohoratskaia, Richard L. Whelan Functional Isolation of Pancreatic Cancer Tumor Suppressor Activity at 12q21-23 Young-Mi Park, Ryan George, Kay Pogue-Geile Gene xpression Profiling of Periampullary Carcinomas: Why Is There Such Heterogeneity in Survival? Kyu-Taek Lee, Jin-Suk Heo, Sung-Ho Choi, Mary Oslen, Brown Patrick, Anson Lowe Marker evelopment for arly etection of Pancreatic Cancer Kay Pogue-Geile, Ryan George, avid Crispin, Teresa Brenmall, James Lyons-Weiler, avid Whitcomb Pancreatic Cancer Associated Gene xpression from FNA Samples ifferentiates Neoplastic Pancreatic Masses from Normal Pancreas and Chronic Pancreatitis Michelle A. Anderson, Baoan Ji, iane M. Simeone, Beth Weinman, James Scheiman, Craig. Logsdon AM-5:00 PM Hall F Sponsored by: Growth, evelopment and Aging AGING AN TH GUT The Long-Term Impact of eglutitive Aspiration in Acute Stroke: A 7 Year Prospective Study Maxine Power, Shaheen Ham@, Salil Singh, Pippa Tyrrell, avid Thompson Age, Hospitalizations, and Case-Fatality Rates ue to Complicated Gastric and uodenal Ulcers in the United States: How Old is Old? Gurkirpal Singh, Alka Mithal, George Triadafilopoulos AM-5:00 PM Hall F Sponsored by: Intestinal isorders WOUN HALING AN CLL POLARITY W1726 W1727 phb/phrin-b Signaling nhances Intestinal Restitution: A Novel Protective Mechanism Thomas Vogt, Christian Hafner, Stefanie Meyer, Thomas Langmann, Gerd Schmitz, Johannes Grossmann, Gerhard Rogler, Frauke Bataille, Michael Landthaler Vascular ndothelial Growth Factor (Rat VGF164) Promotes Intestinal pithelial Restitution in vitro: vidence for a TGF-]~I Mediated ffect Kerem Bulut, Christian Pennartz, Peter Felderbauer, Nikolaus Ansorge, Rainer Lebert, Ilka Werner, Frank Schmitz, Wolfgang Schmidt, Peter Hoffmann Regulation of Post-Surgical Fibrosis by the Programmed eath-1 (P-1) Pathway Matthew Holsti, Tanuja Chitnis, Ronald J. Panzo, Roderick T. Bronson, Hideo Yagita, Mohamed H. Sayegh, Arthur O. Tzianabos P enotes W Poster of istinction