COMPLEX SKIN CANCERS

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1 Memorial Sloan Kettering Cancer Center is pleased to announce CONTEMPORARY MANAGEMENT OF COMPLEX SKIN CANCERS NOVEMBER 3-4, 2017 Rockefeller Research Laboratories 430 East 67th Street New York, NY 10065

2 COURSE OVERVIEW The purpose of this course is to provide the attendee with a multidisciplinary management approach for patients with skin cancer, including basal cell carcinoma, squamous cell carcinoma, merkel cell carcinoma, melanoma and other complex skin cancers. The topics will focus on advances in epidemiology, pathology and imaging, medical and surgical management and radiation therapy. Complex skin cancer cases will be presented and discussed in a tumor board style with a multidisciplinary panel of experts. TARGET AUDIENCE The target audience includes physicians and allied health professionals, who care for patients with skin cancer, including dermatologists, surgical and medical oncologists, otolaryngologists, ophthalmologists, general surgeons, plastic surgeons, pathologists and radiation oncologists. EDUCATIONAL OBJECTIVES Describe melanoma and non melanoma skin cancer incidence and behavior. Define factors contributing to behavior and outcome of skin cancers. Define characteristics of skin cancers that require aggressive treatment. Understand benefits, limitations, and integration of different modalities used in the treatment of skin cancers. Review novel approaches to optimize surgical treatment of skin cancers. Assess role and variety of radiotherapeutic approaches to complex skin cancers. Review role of biological therapy in the treatment of advanced skin cancers. Examine the optimal approaches toward reconstruction of defects resulting from resection of skin cancers.

3 MSK COURSE DIRECTORS Kishwer S. Nehal, MD Director, Mohs Micrographic and Dermatologic Surgery Dermatology Service Bhuvanesh Singh, MD, PhD Director, Laboratory of Epithelial Cancer Biology Head and Neck Service, MSK FACULTY Robert J. Allen, Jr., MD Plastics and Reconstructive Service Charlotte Ariyan, MD, PhD Associate Attending Surgeon Gastric and Mixed Tumor Service Division of General Surgical Oncology Christopher Barker, MD Radiation Oncologist Department of Radiation Oncology Klaus J. Busam, MD Director of Dermatopathology Department of Pathology Chih-Shan Jason Chen, MD, PhD Attending Physician Director of Dermatologic Surgery Hauppaugue Dermatology Section Daniel Coit, MD Attending Surgeon Gastric and Mixed Tumor Service Division of General Surgical Oncology Sandra D Angelo, MD Sarcoma Medical Oncology Service Lara Dunn, MD Head and Neck Oncology Service Alan Ho, MD, PhD Physician Head and Neck Service Division of Solid Tumor Oncology Travis Hollmann, MD, PhD Attending Pathologist Surgical Pathology Service Department of Pathology Erica Lee. MD Physician Dermatology Service Cecilia Lezcano, MD Pathologist Department of Pathology Vanessa Marcell, MS, CGC Senior Genetic Counselor Clinical Genetics Service Alina Markova, MD Dermatology Service Evan Matros, MD Associate Attending Surgeon Plastic and Reconstructive Service Snehal Patel, MD Attending Surgeon Head and Neck Service Tatyana Petukhova, MD Fellow Dermatology Service Melissa Pulitzer, MD Attending Pathologist Surgical Pathology service Department of Pathology Nadeem Riaz, MD Radiation Oncologist Associate Director of Genomics Operations, Immunogenomics and Precision Oncology Platform Radiation Oncology Service Benjamin Roman, MD Head and Neck Service Anthony Rossi, MD Physician Dermatology service Alex Shoushtari, MD Solid Tumor Oncology Division Melanoma and Immunotherapeutics Service Hilda Stambuk, MD Attending Radiologist Neuroradiology Service Department of Radiology INVITED FACULTY Elaine Fuchs, PhD Investigator, Howard Hughes Medical Institute Rebecca C. Lancefield Professor Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University Richard Scolyer, MBBS, MD Senior Staff Specialist, Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital Clinical Professor, Discipline of Pathology, Central Clinical School, Sydney Medical School, The University of Sydney Co-Medical Director, Melanoma Institute Australia

4 SCIENTIFIC AGENDA DAY 1 Friday, Nov 3, :30 am BREAKFAST & REGISTRATION 8:00 am Introductory Remarks Bhuvanesh Singh, MD, PhD Kishwer S. Nehal, MD BASAL CELL CARCINOMA MODERATOR: Kishwer S. Nehal, MD 8:10 am High Risk BCC & Role of Comorbidity and Quality of Life in Decision Making Erica Lee, MD 8:25 am Practical Reconstruction Pearls Evan Matros, MD 8:40 am Optical Imaging of BCC: Beyond Diagnosis Chih-Shan Jason Chen, MD, PhD 8:55 am Basics of Radiographic Imaging for Head & Neck Skin Cancer Hilda Stambuk, MD 9:10 am Radiotherapy as an Alternative to Surgery Christopher Barker, MD 9:25 am Update on Targeted Therapies Alan Ho, MD, PhD TUMOR BOARD - BCC Travis Hollmann, MD, PhD and All Faculty 9:40 am Multidisciplinary Challenging Cases 10:40 am BREAK SYNDROMES & SKIN CANCER MODERATOR: Klaus J. Busam, MD 11:00 am More Than Skin Deep: Hereditary Syndromes Associated with Skin Cancer Alina Markova, MD 11:30 am Pathology of Syndrome-Associated Adnexal Tumors Cecilia Lezcano, MD 11:50 am Decoding the Genetic Counselor s Role in Hereditary Syndromes Involving Skin Cancer Vanessa Marcell, MS, CGC 12:05 pm Multidisciplinary Challenging Cases Q&A 12:30 pm LUNCH

5 SQUAMOUS CELL CARCINOMA MODERATOR: Bhuvanesh Singh, MD, PhD 1:45 pm Molecular Pathogenesis of SCC of the Skin Elaine Fuchs, PhD 2:05 pm SCC of the Skin Classification and Clinically Relevant Pathology Richard Scolyer, MBBS, MD 2:25 pm Approach to Management of SCC in Danger Areas of the Head and Neck Region Snehal Patel, MD 2:40 pm When and How to Assess and Manage Metastasis from SCC to Regional Nodes Bhuvanesh Singh, MD, PhD 3:00 pm Role of Radiation Therapy Christopher Barker, MD 3:15 pm Novel Systemic Treatments Lara Dunn, MD TUMOR BOARD - SCC Benjamin Roman, MD and All Faculty 3:30 pm Multidisciplinary Challenging Cases 4:30 pm DAY 1 ADJOURN

6 SCIENTIFIC AGENDA DAY 2 Saturday, Nov 4, :00 am BREAKFAST MERKEL CELL CARCINOMA MODERATOR: Christopher Barker, MD 8:30 am Merkel Cell Carcinoma Pathology Melissa Pulitzer, MD 8:45 am Genomics of MCC and Implication for Clinical Targeting Nadeem Riaz, MD 9:00 am Radiation Therapy in the Treatment of MCC Christopher Barker, MD 9:15 am Systemic Treatment Options Sandra D Angelo, MD TUMOR BOARD MCC All Faculty 9:30 am Multidisciplinary Challenging Cases 10:30 am BREAK LENTIGO MALIGNA MELANOMA MODERATOR: Klaus J. Busam, MD 10:45 am Challenges in Surgical Management Kishwer S. Nehal, MD 11:00 am Lentigo Maligna Melanoma Pathology Richard Scolyer, MBBS, MD 11:15 am Putting It Back Together: The Reconstructive Ladder Robert J. Allen, Jr., MD 11:30 am Role of Imiquimod & Confocal Imaging Anthony Rossi, MD TUMOR BOARD LMM All Faculty 11:45 am Multidisciplinary Challenging Cases 12:30 pm LUNCH

7 MELANOMA MODERATOR: Charlotte E. Ariyan, MD, PhD 1:30 pm AJCC 8th Edition Melanoma Staging Updates and Melanoma Genetics Richard Scolyer, MBBS, MD 2:00 pm Evolution in Management of Nodal Disease Daniel Coit, MD 2:20 pm Pathologic Assessment and Reporting of Margins Klaus J Busam, MD 2:35 pm Adjuvant Surgery Charlotte Ariyan, MD, PhD 2:55 pm Management of Advanced Disease Alexander Shoushtari, MD TUMOR BOARD MELANOMA All Faculty 3:15 pm Multidisciplinary Challenging Cases 4:15 pm CLOSING REMARKS & SYMPOSIUM ADJOURN

8 REGISTRATION EARLY BEFORE 9/8/17 GENERAL AFTER 9/8/17 Physicians (MDs, PhDs, DOs) $400 $450 Fellows, Residents, Nurses, Other Health Care Providers $100 $150 Industry* $785 $785 Register online at: Registration includes continental breakfast, lunch and refreshment breaks. Please contact us at least one week prior to the course if you have any special dietary needs. 30% Discounted Rate for MSK Alumni and MSK Alliance Members MSK offers a 30% discounted rate to all MSK Alumni and MSK Alliance members to attend a CME course. Please contact cme@mskcc.org for a promo code or more information. MSK Staff Registration Registration is complimentary for MSK staff who wish to attend this course. However, you must register online by visiting the course website: ACCREDITATION STATEMENT MSK is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. CREDIT DESIGNATION STATEMENT MSK designates this live activity for a maximum of AMA PRA Category 1 Credits. Physicians should only claim credit commensurate with the extent of their participation in the activity. The AMA has determined that physicians not licensed in the United States but who participate in this CME activity are eligible for AMA PRA Category 1 Credits. FACULTY DISCLOSURE It is the policy of MSK to make every effort to insure balance, independence, objectivity and scientific rigor in all continuing medical education activities which it sponsors as an ACCME accredited provider. In accordance with ACCME guidelines and standards, all faculty participating in an activity sponsored by MSK are expected to disclose any significant financial interest or other relationship with the manufacturer(s) of any commercial product(s) and/or provider(s) of commercial services which are discussed by the faculty members in an educational presentation. As required by the ACCME, when an unlabeled use of a commercial product or an investigational use not yet approved for any purpose is discussed during an educational activity, MSK requires the speaker to disclose that the product is not labeled for the use under discussion or that the product is still investigational ACCOMMODATIONS For travel information, including hotels in the area of MSK with discounted rates, please visit: CONTINUING MEDICAL EDUCATION MEMORIAL SLOAN KETTERING CANCER CENTER 633 Third Avenue, 12th Floor, New York, NY cme@mskcc.org MSK CME LinkedIn Group

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