ON O C N O C H O E H M E A M T A O T L O O L G O Y

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1 REAL TIME PCR KITS von AB Analitica ONKOHÄMATOLOGIE INFEKTIOLOGIE HUMANGENTIK CE IVD gleiches PCR Protokoll REALQUALITY CATALOGUE

2 REALQUALITY REAL TIME PCR KITS Characteristics: CE IVD Same Thermal cycling profiles Validated on the most common automatic extraction and Real time PCR instruments Software for automatic interpretation of results Internal and positive controls are included dutp/ung system for preventing carry-over contaminations Fluorescent normalizer INFECTIOUS DISEASES REALQUALITY RS-CHLAM T RQ-S33-48 RQ-S33-96 Detection of Chlamydia trachomatis DNA REALQUALITY RQ-CHLAM T STANDARD RQ-34-ST 4 60 µl Chlamydia trachomatis DNA REALQUALITY RQ-CMV RQ-S09-48 RQ-S09-96 Detection of Cytomegalovirus DNA REALQUALITY RQ-CMV STANDARD RQ-10-ST 4 60 µl Cytomegalovirus DNA REALQUALITY RS-EBV RQ-S11-48 RQ-S11-96 Detection of Epstein Barr Virus DNA REALQUALITY RQ-EBV STANDARD RQ-12-ST 4 60 µl Epstein Barr Virus DNA REALQUALITY RS-HSV 1 RQ-S05-48 RQ-S05-96 Detection of Herpes simplex virus type 1 DNA REALQUALITY RQ-HSV 1 STANDARD RQ-06-ST 4 60 µl Herpes simplex virus type 1 DNA REALQUALITY RS-HSV 2 RQ-S07-48 RQ-S07-96 Detection of Herpes simplex virus type 2 DNA REALQUALITY RQ-HSV 2 STANDARD RQ-08-ST 4 60 µl Herpes simplex virus type 2 DNA REALQUALITY RS-HHV 6 RQ-S15-48 RQ-S15-96 Detection of Human Herpes virus type 6 DNA REALQUALITY RQ-HHV 6 STANDARD RQ-16-ST 4 60 µl Human Herpes virus type 6 DNA REALQUALITY RS-HHV 7 RQ-S19-48 RQ-S19-96 Detection of Human Herpes virus type 7 DNA REALQUALITY RQ-HHV 7 STANDARD RQ-20-ST 4 60 µl Human Herpes virus type 7 DNA REALQUALITY RS-HHV 8 RQ-S17-48 RQ-S17-96 Detection of Human Herpes virus type 8 DNA REALQUALITY RQ-HHV 8 STANDARD RQ-18-ST 4 60 µl Human Herpes virus type 8 DNA REALQUALITY RS-VZV RQ-S35-48 RQ-S35-96 Detection of Varicella zoster virus DNA REALQUALITY RQ-VZV STANDARD RQ-36-ST 4 60 µl Varicella zoster virus DNA

3 REALQUALITY RQ-ENTERO RQ RQ Detection of Enterovirus RNA REALQUALITY RQ-ENTERO STANDARD RQ-90-ST 4 60 µl Enterovirus RNA REALQUALITY RS-BKV RQ-S49-48 RQ-S49-96 Detection of BK virus DNA REALQUALITY RQ-BKV STANDARD RQ-50-ST 4 60 µl BK virus DNA REALQUALITY RS-JCV RQ-S83-48 RQ-S83-96 Detection of JC virus DNA REALQUALITY RQ-JCV STANDARD RQ-84-ST 4 60 µl JC virus DNA REALQUALITY RS-PARVO B19 RQ-S37-48 RQ-S37-96 Detection of Parvovirus B19 DNA REALQUALITY RS-PARVO B19 STANDARD RQ-38-ST 4 60 µl Parvovirus B19 DNA REALQUALITY RS-ADENO RQ-S93-48 RQ-S93-48 Detection of Adenovirus DNA REALQUALITY RQ-ADENO STANDARD RQ-94-ST 4 60 µl Adenovirus DNA REALQUALITY RQ-MBT Complex RQ RQ Detection of Mycobacterium tuberculosis complex DNA REALQUALITY RQ-MBT Complex STANDARD RQ-86-ST 4 60 µl Mycobacterium tuberculosis complex DNA REALQUALITY RS-CHLAM P RQ-S45-48 RQ-S45-96 Detection of Chlamydophila pneumoniae DNA REALQUALITY RQ-CHLAM P STANDARD RQ-46-ST 4 60 µl Chlamydophila pneumoniae DNA REALQUALITY RS-MYCO P RQ-S47-48 RQ-S47-96 Detection of Mycoplasma pneumoniae DNA REALQUALITY RQ-MYCO P STANDARD RQ-48-ST 4 60 µl Mycoplasma pneumoniae DNA coming soon SOON AVAILABLE FOR INFECTIOUS DISEASES: Legionella pneumophila Sexually transmitted disease pathogens HUMAN PAPILLOMAVIRUS REALQUALITY RI-HPV STAR RI RI Identification of Human Papillomavirus The amplicons of positive samples can be genotyped on strips to define the carcinogenic risk by using: AMPLIQUALITY HPV-TYPE 03-29R tests

4 THROMBOPHILIA REALQUALITY RS-FATTORE V Leiden RQ-S25-48A RQ-S25-96A Detection and genotyping of mutation G1691A (Leiden) in the human gene coding for factor V REALQUALITY RS-FATTORE II G20210A RQ-S27-48A RQ-S27-96A Detection and genotyping of mutation G20210A in the human gene coding for factor II REALQUALITY RS-MTHFR C677T RQ-S29-48A RQ-S29-96A Detection and genotyping of mutation C677T in the human gene coding for MTHFR REALQUALITY RS-MTHFR A1298C RQ-S31-48A RQ-S31-96A Detection and genotyping of mutation A1298C in the human gene coding for MTHFR REALQUALITY RS-FATTORE V H1299R RQ-S71-48A RQ-S71-96A Detection and genotyping of mutation H1299R (haplotype HR2) in the human gene coding for factor V REALQUALITY RS-FATTORE V Y1702C RQ-S69-48 RQ-S69-96 Detection and genotyping of mutation Y1702C in the human gene coding for factor V REALQUALITY RS-PAI-1 4G/5G RQ-S73-48A RQ-S73-96A Detection and genotyping of polymorphism G/5G in the human gene coding for Plasminogen activator inhibitor-1 REALQUALITY RS-ACE (I/D) RQ-S75-48 RQ-S75-96 Detection and genotyping of insert/deletion (I/D) polymorphism in intron 16 of the human gene coding for angiotensin converting enzyme (ACE) HEMOCHROMATOSIS REALQUALITY RS-HEMO C282Y RQ-S39-48A RQ-S39-96A Detection and genotyping of C282Y mutation in the human HFE gene REALQUALITY RS-HEMO H63D RQ-S41-48A RQ-S41-96A Detection and genotyping of H63D mutation in the human HFE gene REALQUALITY RS-HEMO S65C RQ-S43-48A RQ-S43-96A Detection and genotyping of S65C mutation in the human HFE gene PHARMACOGENETICS REALQUALITY RI-KRAS MuST RI RI test 60 test Detection of mutations in codon 12 and 13 of the k-ras oncogene REALQUALITY RI-BRAF MuST RI RI test 60 test Detection of mutation V600E in the b-raf oncogene REALQUALITY RS-IL28B rs RQ RQ Detection and genotyping of polymorphism rs in the human gene coding for Interleukin 28B REALQUALITY RQ-IL28B rs RQ RQ Detection and genotyping of polymorphism rs in the human gene coding for Interleukin 28B

5 ONCOHEMATOLOGY REALQUALITY RS-JAK-2 V617F Q RQ-S81-48A RQ-S81-96A Absolute quantification of V617F mutation in the JAK-2 gene REALQUALITY RS-JAK-2 V617F RQ-S51-48A RQ-S51-96A Semiquantitative identification of the V617F mutation in the JAK-2 gene REALQUALITY RS-JAK-2 V617F variante screening RQ-S51S-48 RQ-S51S-96 Detection of V617F mutation in the JAK-2 gene REALQUALITY RS-BCR-ABL p210 RQ-S53-48 RQ-S53-96 Detection of t(9;22)(q34;q11) translocation, p210 variant transcript (M-bcr) REALQUALITY RQ-BCR-ABL p210 STANDARD RQ-54-ST 4 x 60 µl BCR-ABL p210 BCR-ABL M-bcr (p210) and ABL transcripts BCR-ABL p210 REFERENCE x 15 µl RNA reference for detection and/or quantification of BCR-ABL p210 transcript REALQUALITY RS-BCR-ABL p190 RQ-S55-48 RQ-S55-96 Detection of t(9;22)(q34;q11) translocation, p190 variant transcript (m-bcr) REALQUALITY RQ-BCR-ABL p190 STANDARD RQ-56-ST 4 x 60 µl BCR-ABL p190 BCR-ABL m-bcr (p190) and ABL transcripts REALQUALITY RS-WT-1 RQ-S57-48 RQ-S57-96 Detection of Wilms Tumor-1 gene transcript REALQUALITY RQ-WT-1 STANDARD RQ-58-ST 4 x 60 µl WT 1 WT-1 and ABL transcripts REALQUALITY RS- AML1-ETO RQ-S59-48 RQ-S59-96 Detection of t(8;21)(q22;q22) translocation, AML1-ETO transcript REALQUALITY RQ-AML1-ETO STANDARD RQ-60-ST 4 x 60 µl AML1-ETO AML1-ETO and ABL transcripts REALQUALITY RS-INV 16 RQ-S61-48 RQ-S61-96 Detection of inv(16)(p13;q22) inversion, CBFβ- MYH11 A transcript REALQUALITY RQ-INV 16 STANDARD RQ-62-ST 4 x 60 µl inv16 inv(16) and ABL transcripts REALQUALITY RS-PML-RARa bcr1 RQ-S63-48 RQ-S63-96 Detection of t(15;17)(q22;q21) translocation, bcr1 variant trancripts REALQUALITY RQ-PML-RARa bcr1 STANDARD RQ-64-ST 4 x 60 µl PML-RARa bcr1 PML-RARa bcr1 and ABL transcripts REALQUALITY RS-PML-RARa bcr2 RQ-S67-48 RQ-S67-96 Detection of t(15;17)(q22;q21) translocation, bcr2 variant transcript REALQUALITY RQ-PML-RARa bcr2 STANDARD RQ-68-ST 4 x 60 µl PML-RARa bcr2 PML-RARa bcr2 and ABL transcripts REALQUALITY RS-PML-RARa bcr3 RQ-S65-48 RQ-S65-96 Detection of t(15;17)(q22;q21) translocation, bcr3 variant transcript REALQUALITY RQ-PML-RARa bcr3 STANDARD RQ-66-ST 4 x 60 µl PML-RARa bcr3 PML-RARa bcr3 and ABL transcripts coming soon SOON AVAILABLE FOR ONCOHEMATOLOGY: MPLW515L and MPLW515K mutations

6 Bio Products Mag. Th. Langmann GmbH Österreich A-2000 Stockerau, Landstraße 4 Tel: +43 (0) , Fax: +43 (0) Deutschland D München, Josephspitalstraße 15 Tel: +49 (0) , Fax: +49 (0) office@bioproducts.at

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