MOC HEM - General Hematopathology (Mandatory 50-Question Module)
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1 MOC HEM - General Hematopathology (Mandatory 50-Question Module) acute monoblastic/monocytic leukemia infectious mononucleosis adult T cell leukemia/lymphoma in situ follicular lymphoma ALL; phenotypes large B-cell lymphoma and variants AML; cytogenetics; immunophenotypes lymphoma, differential diagnosis amyloidosis mantle cell lymphoma, FISH Anaplasma/Ehrlichia mastocytosis autoimmune lymphoproliferative syndrome May-Hegglin anomaly B cells differentiation; IgM micromegakaryocytes BCR/ABL FISH mycosis fungoides & Sezary syndrome bite RBCs myelodysplastic syndromes burr RBCs myeloproliferative neoplasms CSF; malignant cells paroxysmal nocturnal hemoglobinuria DIC pediatric follicular lymphomas essential thrombocythemia, JAK negative plasma cell neoplasms extranodal NK/T-cell lymphoma, nasal type platelet aggregation; ASA factor inhibitors Rosai-Dorfman flow cytometry, CML SOX11 follicular lymphoma t(11;14); techniques for detection GI follicular lymphoma T cell prolymphocytic leukemia hairy cell leukemia Von Willebrand disease Hb S; related disorders zinc toxic effects Hodgkin lymphoma classification
2 MOC HEM Blood & Bone Marrow Pathology (Elective 50-Question Module) abnormal RBC morphology; inclusions Kostmann syndrome acute leukemia of ambiguous lineage liver disease acute myelomonocytic leukemia lymphoplasmacytic lymphoma Alder-Reilly anomaly malaria AML; FISH megaloblastic anemia amyloidosis metastatic neoplasms B-lymphoblastic leukemia; FISH myelodysplastic syndromes; cytogenetics bacterial infections; WBC morphology myeloproliferative neoplasms blood and bone marrow cell identification non-immune hemolytic anemias bone marrow cell identification Parvovirus chronic myelogenous leukemia PDGFRB rearrangements congenital anemias peripheral blood; immature cells copper deficiency peripheral blood; non-hematopoietic cells delta check; misidentified specimen plasma cell myeloma Dohle bodies platelet morphology erythrocytic parasites polycythemia vera erythroid hyperplasia pseudo-chediak Higashi anomaly FISH vs. classical cytogenetics reactive lymphocytosis; WBC infections HbE disorders renal osteodystrophy hematogones rouleaux hemoglobin analysis; HPLC routine and special histologic stains hemolytic disease of the newborn serous atrophy hemophagocytic syndrome sickle solubility test iron deficiency anemia storage disorders; Gaucher disease juvenile myelomonocytic leukemia
3 MOC HEM Flow Cytometry (Elective 50-Question Module) aberrant antigen expression in CLL large granular lymphocytic leukemia acute myelomonocytic leukemia lymphoid hyperplasia; mantle zone acute promyelocytic leukemia lymphoid neoplasms with eosinophilia anaplastic large cell lymphoma mantle cell lymphoma angioimmunoblastic T-cell lymphoma mature T lymphocytes, immunophenotypes autoimmune disorders mature T-cell neoplasms basophils mycosis fungoides & Sezary syndrome B lymphoblastic leukemia/lymphoma myeloid antigens B-cell differentiation sequence NK/T-cell lymphomas CD3; ALL plasma cell leukemia chronic granulomatous disease plasma cell myeloma CLL/SLL; pleural fluid PNH CLL; ZAP 70 quality control CML (BCR-ABL1+) SOX-11 dead cells splenic marginal zone lymphoma EMA binding test T cell maturation follicular lymphoma T-gamma lymphocytosis hematogones T-lymphoblastic leukemia/lymphoma infectious mononucleosis large B-cell lymphoma variants
4 MOC HEM Hemostasis & Thrombosis (Elective 50-Question Module) abciximab international normalized ratio amyloidosis lupus anticoagulant/inhibitor aspirin and platelet function macrothrombocytopenia; genetic defect Bernard-Soulier syndrome mixing studies calibration curve; Protein C PFA 100; closure times clopidogrel platelet aggregation; abciximab clopidogrel; thromboelastometry platelet aggregation; sample collection and processing coagulation factors and pregnancy platelet P2Y12 receptor coagulation testing; heparin proficiency testing performance coagulation testing; serum Prothrombin C20209T mutation; fluorescence resonance energy transfer analysis dabigatran prothrombin genotyping, FRET analysis direct thrombin inhibitors quantitative D-dimer dysfibrinogenemia reticulated platelet counts factor assays; interpretation secondary wave of platelet aggregation factor deficiencies thromboelastograph tracings factor deficiencies; TEG tirofiban; platelet aggregation factor inhibitors TTP factor IX deficiency validation of new reagent lots Glanzmann thrombasthenia von Willebrand disease, types GPIIIa von Willebrand disease; multimer analysis heparin induced thrombocytopenia warfarin ingestion heparin therapeutic range warfarin monitoring, argatroban therapy
5 MOC HEM Laboratory Hematology - No Coag (Elective 50-Question Module) acanthocytes iron deficiency anemia acute monoblastic/monocytic leukemia leukemoid reaction bite cells lipemia; automated blood counts CLIA; moderate vs. high complexity testing MCV cold agglutinins megaloblastic anemia computer interoperability; interfaces monocytes cryoglobulinemia MSDS sheets CSF; non-hematopoietic cells neonatal blood Dohle bodies non-immune hemolytic anemia FDA testing regulations Pelger-Huet anomaly giant platelets; spurious automated counts pertussis Hb C disorders plasma cell myeloma Hb E disorders platelet satellitosis Hb S disorders pseudothrombocytopenia Heinz bodies quality control; moving averages hemoglobinopathy analysis RBC parasites hemoglobinopathy/thalassemia splenectomy; RBC morphology hemolytic uremic syndrome supravital stains Hgb A2 quantitation target RBCs histoplasmosis thalassemias immune hemolytic anemia thrombocytosis; spurious lab results infectious mononucleosis types of data
6 MOC HEM Lymph Node & Related Tissues (Elective 50-Question Module) 7q loss lymphoid hyperplasia; IHC angioimmunoblastic T-cell lymphoma lymphoma karyotypes autoimmune disorders; LNs lymphoplasmacytic lymphoma CLL/SLL MALT lymphomas; cytogenetics CLL/SLL; IHC and flow cytometry mantle cell lymphoma cutaneous T-cell lymphomas mediastinal neoplasms CXCL13 immunostain metastatic neoplasms dendritic cells, IHC mycosis fungoides & Sezary syndrome dermatopathic lymphadenopathy myeloid sarcoma follicular lymphoma grading; WHO nodal marginal zone lymphoma; IHC heavy chain disease normal lymphoid tissue; IHC histiocytic/dendritic neoplasms NOTCH1 mutations histiocytic necrotizing lymphadenitis PD-1/CD279 IHC Hodgkin lymphoma pediatric follicular lymphomas IHC interpretation; pitfalls primary effusion lymphoma in situ follicular lymphoma; IHC sarcoidosis infectious lymphadenitis spenic cysts &other non-hematopoietic lesions Langerhans cell histiocytosis/sarcoma Stark law
MOC HEM - General Hematopathology (Mandatory 50-Question Module)
MOC HEM - General Hematopathology (Mandatory 50-Question Module) acute monoblastic/monocytic leukemia infectious mononucleosis adult T cell leukemia/lymphoma in situ follicular lymphoma ALL; phenotypes
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