Duke at. American Society of Clinical Oncology Chicago, Illinois

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1 Duke at American Society of Clinical Oncology 2017 Chicago, Illinois

2 Duke Medicine Divisions of Hematology Medical Oncology and Hematologic Malignancy & Cellular Therapy Cordially invite you to the Duke reception in conjunction with the ASCO Annual Meeting in Chicago, Illinois Saturday, June 3, :00 p.m. 9:00 p.m. The Hyatt Regency Chicago 151 East Wacker Drive Comiskey Room

3 Conquer Cancer Foundation/AstraZeneca Young Investigator Award Nicholas C. DeVito, MD Duke University Medical Center Investigating Oncogenic Signaling Pathways that Drive Wnt Ligandmediated Immune Tolerance in Melanoma Mentored by: Brent Hanks, MD, PhD

4 Cancer Education Committee Geriatric Oncology Gretchen Kimmick, MD Head and Neck Cancer Joseph K. Salama, MD Health Services Research, Clinical Informatics, and Quality of Care Yousuf Zafar, MD, MHS Scientific Program Committee Biostatistics Susan Halabi, PhD Genitourinary (Nonprostate) Cancer Daniel J. George, MD Patient and Survivor Care Chair-elect, Ethics Committee Scientific Track Chair, Patient and Survivor Care Member, ASCO Taxonomy Subcommittee Thomas LeBlanc, MD, MA Tumor Biology Andrew Nixon, PhD Educational Book: Zhang, T., Gong, J., Caitano, M., Pal, S.K. Systemic therapy for non-clear cell renal cell carcinoma. In ASCO 2017 Educational Book. e Abstract Title: Association of neuroendocrine phenotype with platinum chemotherapy outcomes in men with metastatic prostate cancer. Andrew Armstrong, MD

5 Friday, June 2, :45 PM - 4:15 PM Location: Arie Crown Theater Clinical Science Symposium Expanding the Actionable Landscape: Bladder Cancer Genomics Track(s): Genitourinary (Nonprostate) Cancer Chair(s): Tian Zhang, MD 1:00 PM - 3:15 PM Location: Location: S504 Extended Education Session Moving Beyond the Randomized Controlled Trial: Real-World Data to Inform Patient Care and Policy Track(s): Health Services Research, Clinical Informatics, and Quality of Care; Care Delivery and Practice Management; Clinical Trials; Patient and Survivor Care; Pediatric Oncology; Value PCORnet: A Developing Data Source by Linking Electronic Medical Records Lesley H. Curtis - Speaker Saturday, June 3, :00 AM - 9:15 AM Location: E450ab Education Session Endometrial Cancers of Young and Older Patients: New Observations and Perspectives Track(s): Gynecologic Cancer; Cancer Prevention, Hereditary Genetics, and Epidemiology; Geriatric Oncology; Patient and Survivor Care The Roles of Exercise in Risk Reduction Kathryn Elizabeth Hudson - Speaker 8:00 AM - 11:00 AM Location: S103 Extended Education Session Designing Clinical Trials for an Aging Population Track(s): Geriatric Oncology; Clinical Trials; Disparities; Patient and Survivor Care Chair(s): Gretchen Genevieve Kimmick, MD, MS 8:00 AM - 11:30 AM Gastrointestinal (Colorectal) Cancer Track(s): Gastrointestinal (Colorectal) Cancer Abstract TPS3624 A phase II, open label study of tucatinib (ONT-380) combined with trastuzumab in patients with HER2+ metastatic colorectal cancer (mcrc)(mountaineer). Poster Board: #244a John H. Strickler - First Author

6 Saturday continued 1:15 PM - 4:45 PM Poster Discussion Session Tumor Biology Track(s): Tumor Biology Chair(s): Andrew B. Nixon, PhD Tumor Biology Track(s): Tumor Biology Abstract Biomarker modulation in patients treated with TRC105 in combination with anti-vegf therapy. Poster Board: #246 Yingmiao Liu - First Author Patient and Survivor Care Track(s): Patient and Survivor Care Abstract Risk tolerance and attitudes toward chemotherapy: Who chooses palliative treatment when cure is possible? Poster Board: #43 Thomas William LeBlanc, MD, MA, MHS - First Author Abstract Survivorship needs after head and neck cancer treatment. Poster Board: #51 Callie Berkowitz - First Author Gynecologic Cancer Track(s): Gynecologic Cancer Abstract 5544 Management of platinum-sensitive recurrent ovarian cancer (PSROC) in the era of biologics: Can ASCO s net health benefits (NHB) inform our decisions? Poster Board: #366 Jonathan Foote - First Author Abstract 5571 Evaluating the repertoire of immune checkpoint markers expressed on peripheral and ascites CD8+ T cells in ovarian cancer. Poster Board: #393 Stephanie Gaillard - First Author Abstract TPS10128 Testing a behavioral intervention to improve adherence to adjuvant endocrine therapy (AET) Poster Board: #115a Gretchen Genevieve Kimmick - First Author Saturday continued Location: Hall B1 Oral Abstract Session

7 Genitourinary (Prostate) Cancer Track(s): Genitourinary (Prostate) Cancer Abstract 5006 Phase 3 prognostic analysis of the automated bone scan index (absi) in men with bone-metastatic castrationresistant prostate cancer (CRPC). Andrew J. Armstrong - First Author Interpreting Biomarkers and Trial Outcomes: How Confident Are We? Susan Halabi - Discussant 1:15 PM - 2:30 PM Location: Arie Crown Theater Poster Discussion Session Gastrointestinal (Colorectal) Cancer Track(s): Gastrointestinal (Colorectal) Cancer PET to Plasma: Evolution of Disease Monitoring John H. Strickler - Discussant 4:45 PM - 6:00 PM Location: S404 Poster Discussion Session Patient and Survivor Care Track(s): Patient and Survivor Care Communication, Coping, and Cancer, Discussing Abstract(s): 10021, 10022, Thomas William LeBlanc - Discussant Sunday, June 4, :00 AM - 9:15 AM Location: S504 Is the Sharper Knife Worth the Price? A Discussion of Protons Versus Photons Track(s): Head and Neck Cancer; Value Is the Sharper Knife Worth the Price: Intensity-Modulated Radiation Therapy (Proton Versus Intensity- Modulated Radiation Therapy) David M. Brizel - Speaker 8:00 AM - 9:15 AM Location: S100bc Education Session Starting the Conversation: Interventions to Reduce Financial Toxicity Track(s): Health Services Research, Clinical Informatics, and Quality of Care; Care Delivery and Practice Management; Disparities; Ethics; Value Chair(s): Yousuf Zafar, MD, MHS

8 Sunday continued 8:00 AM - 8:05 AM Overview of Financial Toxicity. Yousuf Zafar, MD, MHS - Chair 8:00 AM - 11:30 AM Poster Discussion Session Genitourinary (Nonprostate) Cancer Track(s): Genitourinary (Nonprostate) Cancer Abstract 4522 Association of on-treatment plasma HGF levels with overall survival (OS) in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (INF) +/- bevacizumab (BEV): Results from CALGB (Alliance). Poster Board: #200 Daniel J. George - First Author Breast Cancer Local/Regional/Adjuvant Track(s): Breast CancerAbstract 532 A population-based analysis of treatment and outcomes in 2,500 metaplastic breast cancer patients. Poster Board: #132 Cecilia Tuongquang Ong - First Author Abstract 554 Role of axillary node dissection after mastectomy with positive sentinel nodes. Poster Board: #154 Tristen Sinae Park - First Author 8:00 AM - 9:30 AM Location: Hall B1 Clinical Science Symposium Old Targets, New Drugs: HER2 and MET Track(s): Lung Cancer; Lung Cancer Abstract 8509 Efficacy, safety, and biomarker results of trastuzumab emtansine (TDM1) in patients (pts) with previously treated HER2-overexpressing locally advanced or metastatic non-small cell lung cancer (mnsclc). Tom Stinchcombe - First Author 9:45 AM - 12:45 PM Location: E354b Oral Abstract Session Hematologic Malignancies Plasma Cell Dyscrasia Track(s): Hematologic Malignancies Plasma Cell Dyscrasia Abstract 8008 Phase I/II dose expansion of a trial investigating bendamustine and pomalidomide with dexamethasone (BPd) in patients with relapsed/refractory multiple myeloma. Dharshan Sivaraj - First Author

9 Monday, June 5, :00 AM - 11:00 AM Location: S100bc Oral Abstract Session Health Services Research, Clinical Informatics, and Quality of Care Track(s): Health Services Research, Clinical Informatics, and Quality of Care 10:12 AM - 10:24 AM Abstract 6507 Implementation of precision oncology in the Veterans Health Administration (VHA). Michael J. Kelley, MD - First Author Department of Veterans Affairs 8:00 AM - 11:30 AM Hematologic Malignancies Plasma Cell Dyscrasia Track(s): Hematologic Malignancies Plasma Cell Dyscrasia Abstract 8023 Impact of t(11;14) on outcomes in African American (AA) and non-aa (NAA) patients (Pts) with newly diagnosed multiple myeloma (NDMM): Connect MM registry. Poster Board: #349 Cristina Gasparetto - First Author Hematologic Malignancies Lymphoma and Chronic Lymphocytic Leukemia Track(s): Hematologic Malignancies Lymphoma and Chronic Lymphocytic Leukemia Abstract 7538 Elucidation of distinct mutational patterns between diffuse large B cell lymphoma subtypes utilizing circulating tumor DNA. Poster Board: #300 Joanne Soo - First Author 1:15 PM - 4:45 PM Genitourinary (Prostate) Cancer Track(s): Genitourinary (Prostate) Cancer Abstract 5022 Development and validation of a prognostic model for overall survival in chemotherapy-naive men with metastatic castration-resistant prostate cancer (mcrpc) from the phase 3 prevail clinical trial. Poster Board: #96 Andrew J. Armstrong - First Author

10 Monday continued Central Nervous System Tumors Track(s): Central Nervous System Tumors Abstract 2049 Number of tumor-infiltrating lymphocytes in breast cancer brain metastases compared to matched breast primaries. Poster Board: #291 Jessie Narloch - First Author (Dr. Kimberly Blackwell) Cancer Prevention, Genetics, and Epidemiology Track(s): Cancer Prevention, Hereditary Genetics, and Epidemiology Abstract 1570 The epidemiology of metaplastic breast cancer: A review of 2,500 cases from the national cancer database. Poster Board: #228 Brittany Morgan Campbell - First Author 1:15 PM - 4:45 PM Health Services Research, Clinical Informatics, and Quality of Care Track(s): Health Services Research, Clinical Informatics, and Quality of Care Abstract 6532 Impact of insurance status on treatment for stage 0-IV breast cancer. Poster Board: #354 Rachel Adams Greenup - First Author Health Services Research, Clinical Informatics, and Quality of Care Track(s): Health Services Research, Clinical Informatics, and Quality of Care Abstract 6608 Cost-effectiveness of ovarian cancer screening: An analysis of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) from a U.S. health system perspective. Poster Board: #430 Haley Moss - First Author

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