VIRUSES AND BREAST CANCER

Transcription

1 Pisa University Hospital University of Pisa Regione Toscana VIRUSES AND BREAST CANCER INTERNATIONAL WORKSHOP April 2-4, 2012 Palazzo Blu LUNGARNO GAMBACORTI, 9 PISA THE WORKSHOP IS IN THE FRAME OF THE REGIONE TOSCANA RESEARCH PROJECT IS BREAST CANCER CAUSED BY A VIRUS? STUDY ON THE ETIOLOGICAL ROLE, PATHOGENETIC MECHANISMS AND SPREADING OF THE HUMAN MAMMARY TUMOR VIRUS INFECTION UNDER THE AUSPICES OF THE EUROPEAN SOCIETY OF PATHOLOGY AND OF ISTITUTO TOSCANO TUMORI IN COLLABORATION WITH THE PALAZZO BLU FOUNDATION

2 APRIL 2, MONDAY 14:00 Welcome Addresses 14:30 Generoso Bevilacqua Remembering Francesco Squartini, Session I CHAIR: JAMES LAWSON, HARALD ZUR HAUSEN 14:45 Harald zur Hausen Viruses in human cancers: reasons to suspect an involvement of infections in human breast cancer? 15:30 Gertrude Buehring Could Bovine Leukemia Virus play a role in human breast cancer? 16:15 Discussion 16:30 COFFEE Session II CHAIR: GERTRUDE BUEHRING, EZEQUIEL MOISES FUENTES PANANÁ 17:00 Mauro Pistello The expanding world of polyomaviruses and cancer. 17:30 James Lawson Multiple viruses in breast cancer: Mouse Mammary Tumor Virus (MMTV), Epstein Barr Virus (EBV), Human Papilloma Virus (HPV), Bovine Leukemia Virus (BLV). 18:15 Discussion APRIL 3, TUESDAY Session III CHAIR: JACOB HOCHMAN, SUSAN ROSS 9:00 Beatriz Pogo MMTV in human cancer, an overview 9:45 Brian Salmons, Walter Gunzburg Past and future perspectives on MMTV 10:30 Discussion 10:45 COFFEE

3 Session IV CHAIR: BEATRIZ POGO, ALEXANDER STEWART 11:15 Generoso Bevilacqua, Chiara Maria Mazzanti MMTV in sporadic and hereditary human breast cancer. 12:00 Jaquelin Dudley What factors affect MMTV replication in human cells? 12:45 Discussion Session V CHAIR: JAQUELIN DUDLEY, CHIARA MARIA MAZZANTI 13:00 LUNCH 14:30 Robert Callahan Common integration sites for MMTV in mammary tumors and their involvement in tumorigenesis. 15:15 Susan Ross MMTV integration site analysis uncovers new pathways involved in breast cancer. 16:00 Discussion Session VI CHAIR: STELLA MELANA, BRIAN SALMONS 16:15 COFFEE 16:45 Andrew Mason Providing definitive proof of MMTV-like viruses in humans: isolation of the human betaretrovirus and detection of integration sites in patients. 17:30 Jacob Hochman New insights into tumor growth regulation by the signal peptide of MMTV-env. 18:15 Discussion APRIL 4, WEDNESDAY Session VII CHAIR: WALTER GUNZBURG, ANDREW MASON 9:00 Stella Melana The host response to HMTV infection 9:45 Ezequiel Moises Fuentes Pananá Screening of EBV, MMTV and HHV7 sequences in breast cancer samples from Mexico. 10:30 Discussion 10:45 COFFEE

4 Session VIII CHAIR: ROBERT CALLAHAN, MAURO PISTELLO 11:15 Alexander Stewart Breast cancer incidence spikes and mouse population explosions in New South Wales, Australia. 11:45 General Discussion 12:15 Generoso Bevilacqua General comment and future plans Speakers: Generoso Bevilacqua, University of Pisa and Pisa University Hospital, Italy Gertrude Buehring, University of California, Berkeley, CA, USA Robert Callahan, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA Jaquelin Dudley, University of Texas, Austin, TX, USA Ezequiel Moises Fuentes Pananá, Hospital de Pediatría, Mexico City, Mexico Walter Gunzburg, University of Veterinary Medicine, Vienna, Austria Jacob Hochman, The Hebrew University, Jerusalem, Israel James Lawson, University of New South Wales, Sydney, Australia Andrew Mason, University of Alberta, Canada Chiara Maria Mazzanti, University of Pisa and Pisa University Hospital Stella Melana, Mount Sinai School of Medicine, New York, NY, USA Mauro Pistello, University of Pisa and Pisa University Hospital, Italy Beatriz Pogo, Mount Sinai School of Medicine, New York, NY, USA Susan Ross, University of Pennsylvania, Philadelphia, PA, USA Brian Salmons, Austrianova Singapore Pte Ltd, Singapore Alexander Stewart, University of Ottawa, Ottawa, Canada Harald zur Hausen, German Cancer Research Center, Heidelberg, Germany

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