CURRICULUM VITAE. University of Florida Medical School, Gainesville, Florida. Doctor of Medicine degree, 1976

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1 CURRICULUM VITAE NAME: ADDRESS: James R. Wells, M.D., F.A.C.S. Dept. of Cell Biology and Anatomy USC School of Medicine Garners Ferry Rd. Bldg. 1, RM. C-36 Columbia, SC EDUCATION: University of Florida, Gainesville, Florida. Bachelor of Science degree, Chemistry major (high honors). University of Florida Medical School, Gainesville, Florida. Doctor of Medicine degree, 1976 Clinical Clerkship in Otolaryngology at Madigan Army Medical Center, Tacoma, Washington. May-June, INTERNSHIP: Madigan Army Medical Center, Tacoma, Washington. July 1, 1976 June 30, RESIDENCY Madigan Army Medical Center, Tacoma, Washington. TRAINING: Otolaryngology Residency, July 1, 1978 June 30, L.L. Hays, M.D.,F.A.C.S. Director. FELLOWSHIP Head and Neck Surgery, Swedish Hospital Medical Center, TRAINING: Seattle, Washington, July 1, 1983 June 30, Alvin J. Novack, M.D., F.A.C.S. Director. SPECIALTY American Board of Otolaryngology, CERTIFICATION: November 9, PROFESSIONAL Chief of Otolaryngology/Ophthalmology, 5 th General Hospital, AFFILIATIONS: Bad Cannstatt, Germany, PROFESSIONAL Fellow in Head and Neck Reconstructive Surgery, Swedish AFFILIATIONS Hospital Medical Center, Seattle, Washington, continued: Assistant Chief of Otolaryngology/Head and Neck Surgery Service, Madigan Army Medical Center, Tacoma, Washington, Private practice- CENTA Medical Group, P.A., Columbia,

2 South Carolina, January, 1986 thru Sept Chief Otolaryngology/ H&N Surgery svc WJB Dorn VA Medical Center 6439 Garner s Ferry Rd. Columbia, SC Clinical Assistant Professor, Department of Surgery, University of South Carolina School of Medicine April Present Coarse Director Medical Embryology & Anatomy Research Professor, Department of Cell& Developmental Biology & Anatomy, University of South Carolina School of Medicine, Since January 2001 Courtesy Staff Palmetto Health Alliance, Columbia, South Carolina. Liaison for The American College of Surgeons to the Dorn VA Medical Ctr Chairman Cancer Committee Dorn VA Medical Ctr PROFESSIONAL SOCIETIES: American Academy of Otolaryngology Head and Neck Surgery, 1987 Columbia Medical Society Fellow, American Society of Head and Neck Surgery, 1992 Diplomate, National Board of Medical Examiners, 1976 South Carolina Oncology Society South Carolina Society of Otolaryngology Fellow, American College of Surgeons, 1990 MILITARY University of Florida Army ROTC, EXPERIENCE: University of Florida, Health Professional Scholarship Program (AR Army), Madigan Army Medical Center, th General Hospital, Bad Cannstatt, Germany, Fellowship in Head and Neck Surgery, Swedish Hospital Medical Center, Seattle, Washington, Alvin J. Novack, M.D., F.A.C.S., Director. ENT staff physician-madigan Army Medical Center,

3 HONORS: National Merit Scholar, 1968 Bachelor of Science, Chemistry, University of Florida, , with high honors Distinguished Military Student and Graduate, University of Florida, Scabbard and Blade Military Honor Society, University of Florida, 1970 Military sponsored scholarship undergraduate ( ) and ( ) medicine. University of South Carolina School of Medicine University of South Carolina School of Medicine University of South Carolina School of Medicine University of South Carolina School of Medicine String of Pearls lecturer,university of South Carolina School of Medicine String of Pearls lecturer,university of South Carolina School of Medicine String of Pearls lecturer,university of South Carolina School of Medicine String of Pearls lecturer,university of South Carolina School of Medicine Elected member AOA, University of South Carolina School of Medicine 2011.

4 PROFESSIONAL Soft Tissue Workshop. Portland, Oregon. November, 1976 COURSES: Maxillofacial Trauma Course. Davis, California. March, 1978 Jackson Clinic Broncho-esophagology Course. October, 1978 Armed Forces Institute of Pathology Course. April-May, 1980 House Otology Course. Los Angeles, California. October- November, 1980 Microsurgery Training. San Francisco, California. September, 1984 Functional Endoscopic Nasal Surgery. Johns Hopkins Medical Center, Baltimore, Maryland. July, 1986 LASERs in Otorhinolaryngology Workshop. State University of New York Health Science Center at Brooklyn. November 3-4, th Annual Symposium: Care of the Professional Voice. Philadelphia. June 6-13, 1989 Second Annual Symposium: Care of the Voice. Panel Moderator. Carolina Center for Laryngology and Voice Disorders. Columbia, South Carolina. October, th Annual Symposium: Care of the Professional Voice. Philadelphia. June 3-8, 1990 LASERs In Tracheobronchoscopy, Lahey Clinic, Boston, Ma. Stanley Shapshay, M.D., Director. February, 1992 Advanced Course in Endoscopic Nasal Surgery, Univ. of Ga. Fred Kuhn, M.D., Director. March, 1994 Minimally Invasive Surgery Update, The USCSOM-PRMH CME Organization, Columbia, SC. June 7, PUBLICATIONS: Microvascular Surgery: A Self-Instructional Method. Exhibit at American Academy of Otolaryngology, Anaheim, California, September-October, 1980 A Reliable Guinea Pig Model for Otologic Research. First Prize for Best Resident Paper, Society of Military Otolaryngologists, Published in Otolaryngology/Head and Neck Surgery, vol. 95, no. 4, pp , November, 1986

5 A Reliable Guinea Pig Model for Otologic Research. Exhibit at American Academy of Otolaryngology, New Orleans, LA, September, 1981 A Method of Removing Displaced Silicone Tubing from the Nasolacrimal Duct System. Published in The American Journal of Ophthalmology, vol. 99, no. 6, pp , June, 1985 A Technique for the Placement of a Long-Term Hyperalimentation Catheter in the Head and Neck Oncology Patient. Otolaryngology Head and Neck Surgery, vol. 95, no. 5, pp , December, 1986 Bony Ossicular Fixation Using Histoacryl Adhesive. Accepted for publication by the Archives of Otolaryngology, vol. 113, pp , June, 1987 Therapeutic Effects of Cisapride for Laryngeal Manifestations of GER. Gastroenterology, AA180, 114, 1998 Esophageal Dysmotility as an Important Co-Factor in Extraesophageal Manifestations of GER. The Laryngoscope, May, The Frequency and Spectrum of Esophageal Motility Disorders in Supraesophageal Manifestations of GERD. Gastroenterology, A3212, May, 2000 Ultrasound in Medical Education: A Vertical Curriculum at the University of South Carolina School of Medicine. The Journal of the South Carolina Medical Association Vol. 102 Dec 2006 Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck Clinical Cancer Research. Dec PAPERS PRESENTED: Parathyroid Localization and SPECT Imaging. Minimally Invasive Surgery Update, The USCSOM-PRMH CME Organization, Columbia, SC. June 7, The Use of Image Guidance in Skull Base Surgery.. The South and North Carolina Society of Otolaryngology/ Head and Neck Surgery. Ashville, N.C., July 2000

6 Esophageal Dysmotility as an Important Co-Factor in Supraesophageal Manifestations of GERD. The American Laryngological, Rhinological and Otological Society, aka the Triological Society, St. Petersburg, FLA, January, 2000 The Frequency and Spectrum of Esophageal Dysmotility Disorders in Supraesophageal Manifestations of GERD. Digestive Disease Week, The American Gastroenterological Association, San Diego, CA, May, Therapeutic Effects of Cisapride in the Treatment of Atypical GERD. The South and North Carolina Society of Otolaryngology/Head and Neck Surgery. Myrtle Beach, SC, July, Therapeutic Effects of Cisapride in Otolaryngologic Manifestations of Gastroesphageal Reflux Disease (GERD). The American Osteopathic Association Convention and Scientific Seminar, New Orleans, LA, November, 1995 Treatment of Spasmodic Dysphonia: A Team Approach in a Community-Based Center. The American Laryngological, Rhinological and Otological Society, aka The Triological Society, Key West, FLA, January, 1995 Free Flap Reconstruction of the Cervical Esophagus. Presented before the South Carolina Surgical Society, Asheville, N.C., June, 1994 Speech Characteristics of Laryngectomy Patients Using the Groningen Valve Prosthesis. The American Laryngological, Rhinological and Otological Society, aka The Triological Society, Marco Island, FLA, January The Gronigen T.E.P. Presented before the Southern Section of the Triologic Society, Marco Island, Fla., January, 1993 Treatment of Spasmodic Dysphonia with Localized Injections of Botulinum Toxin. Respiratory Therapy Association, Baptist Medical Center, Columbia, SC, December Facial Paralysis Secondary to Malignant Adnexal Tumor: Case Report. Presented before the American Academy of Otolaryngology in New Orleans, Louisiana, September, 1981

7 EXTRAMURAL Therapeutic Effects of Cisapride for Laryngeal Manifestations FUNDING: of GERD. Janssen Research Foundation, $20,710. Esophageal Dysmotility as a Co-Factor in Supraesophageal Manifestations of GERD. Janssen Research Foundation, $25,000. FUNDED CLINICAL RESEARCH: Aventis V-324: A Randomized Phase III Trial of Neoadjuvant Docetaxel (Taxotere) plus Cisplatin and 5-Fluorouracil (TPF) vs Neoadjuvant Cisplatin plus 5-FU Followed by Concomitant Chemoradiotherapy to Improve the Overall Survival and Progression-Free Survival in Locally Advanced SCCHN, Co-Investigator closed out Sanofi~Synthelabo EFC4690: Phase III Randomized Trial of Concomitant Radiation, Cisplatin, and Tirapazamine (SR259075) Versus Concomitant Radiation and Cisplatin in Patients with Advanced Head and Neck Cancer, Co-Investigator BMS CA : A Randomized, Double-Blind, Parallel, Three Arm, Multicenter, Phase II Trial Evaluating the Efficacy and Safety of Ipilimumab (BMS ) in Combination with Taxol /Paraplatin (paclitaxel/carboplatin) Compared to Taxol /Paraplatin alone in Previously Untreated Subjects with Lung Cancer, Co-Investigator- closed out GSK A: A double-blind, randomized, placebo-controlled phase III study to assess the efficacy of recmage-a3 + AS15 Antigen-Specific Cancer Immunotherapeutic as adjuvant therapy in patients with resectable MAGE-A3 positive non-small cell lung cancer, Principle-Investigator PR : a randomized phase II, multi-center, open-label trial of PR104 and docetaxel in patients with advanced non-small cell lung cancer- Principle investigator-closed out The role of plastination as a teaching tool in first year gross anatomy- USC School of Medicine- Dept of Cell Biology & Anatomy Aug. 2011

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