2016 CRUK Lung Cancer Centre of Excellence Student/Postdoc Winter Workshop Programme

Transcription

1 2016 CRUK Lung Cancer Centre of Excellence Student/Postdoc Winter Workshop Programme Thursday 1 st December am 10.00am Registration and Refreshments 10.15am 10.30am Welcome 10.30am 11.15am Opening Keynote Lecture Title: TBC Speaker: Professor John Haanen (Netherlands Cancer Institute) Session 1: Tumour Heterogeneity and Biomarkers Chair: Francesca Trapani (CRUK Manchester Institute) 11.15am 11.30am Francesca Chemi (CRUK Manchester Institute) Title: Molecular Profiling of Circulating Tumour Cells (CTCs) in Non-small cell lung cancer within the TRACERx study of Intratumoural Heterogeneity and Evolution 11.30am 11.45am Neele Drobnitzky (CRUK/MRC Oxford Institute for Radiation Oncology) Title: Novel targets for combination therapy in EGFR mutated NSCLC 11.45am 12.00pm Morning Break (Tea/Coffee) 12.00pm 12.15pm Garima Khandelwal (CRUK Manchester Institute) Title: Thermodynamic profile based long non coding RNA structure classification

2 12.15pm 12.45pm Confirmed Lecture Title: Monitoring treatment response by combining immunopet and exosomal imaging of the RTK dimers in lung cancer Speaker: Professor Tony Ng (King s College London/UCL Cancer Institute) 12.45pm 2.30pm Lunch, Networking and Meet the Experts Meet the Experts Several CRUK Lung Cancer Centre of Excellence academics will be available over the course of lunch to answer any questions/discuss potential research ideas with you or any funding opportunities you might want to pursue. Session 2: Mechanisms Driving Lung Tumorigenesis Chair: Jing Bi (CRUK Manchester Institute) 2.35pm 2.50pm Esther Castellano Sanchez (Barts Cancer Institute) Title: RAS binding to PI3K regulates cell adhesion in non-small cell lung carcinoma 2.50pm 3.05pm Anthony Chiu (CRUK Manchester Institute) Title: Multi-omics analysis of circulating tumour cell-derived explants in small cell lung cancer 3.05pm 3.20pm David Moore (University of Leicester) Title: Genomic events in the shift from in situ to invasive disease in lung adenocarcinoma 3.20pm 3.35pm Rajat Roy (Imperial College London) Title: Novel Therapeutic target potentiates sensitivity to chemotherapeutic agents in Lung and Bladder Cancer

3 3.35pm 4.05pm Confirmed Lecture Title: Cell death and ubiquitin: implications for lung cancer Speaker: Professor Henning Walczak (UCL Cancer Institute) 4.05pm 4.20pm Afternoon Break (Tea/Coffee) Session 3: Cancer Immunology and Immunotherapies Chair: James Reading (UCL Cancer Institute) 4.20pm 4.35pm Kroopa Joshi (UCL Cancer Institute) Title: Deciphering the intra-tumoural T cell receptor repertoire in patients with NSCLC within the lung TRACERx study 4.35pm 4:50pm Suzanne Graef (University of Birmingham) Title: Understanding the Role of Myeloid Derived Suppressor Cells in the Microenvironment of Mesothelioma 4.50pm End of first day 5.15pm 7pm Poster Viewing/Networking 7.00pm Onwards Dinner

4 Friday 2 nd December am 8.45am Breakfast 9.00am 9.45am Keynote Lecture Title: TBC Speaker: Professor Caroline Dive (CRUK Manchester Institute) Session 4: Early Detection & Pre-Invasive Disease Chair: Vitor Teixeira (Lungs for Living Research Centre, UCL) 9.45am 10.00am Vitor Teixeira (Lungs for Living Research Centre, UCL) Title: Early cancerous lesion density is pre-defined by gene expression and a fixed epigenetic landscape on a heterogeneous genetic background 10.00am 10.15am Fiona Taylor (Weston Park Hospital, Sheffield) Title: Non-invasive detection of lung cancer by identifying copy number aberrations in circulating cell-free DNA with next generation sequencing 10.15am 10.45am Confirmed Lecture Title: TBC Speaker: Professor Sam Janes (Lungs for Living Research Centre, UCL) 10.45am 11.15am Morning Break (Tea/Coffee)

5 Session 5: Radiotherapy & Drug Discovery Chair: Francisco Zambrana (UCL Cancer Institute) 11.15am 11.30am Banu Rudran (Barts Cancer Institute) Title: Development of non-invasive imaging of integrin alpha-v-beta-6 (avb6)- positive lung cancers in advance of testing avb6-targeted therapies 11.30am 11.45am Hannah Bainbridge (Institute of Cancer Research/The Royal Marsden NHS Foundation Trust) Title: Domestic Implications for Radical Radiation Therapy on the 1.5 Tesla Magnetic Resonance Linear Accelerator (MR-Linac) in Locally-Advanced Non- Small Cell Lung Cancer 11.45pm 12.15pm Confirmed Lecture Title: Discovery of potent, selective inhibitors of RET and their potential use in lung cancer Speaker: Dr Ian Waddell (CRUK Manchester Institute) 12.15pm 1.15pm Lunch Session 6: Academic Careers, Advice & Funding Opportunities Confirmed Speakers: Dr Richard Oakley (CRUK Senior Funding Manager) Dr Crispin Miller (CRUK Manchester Institute) Talks will be followed by a careers Q&A session. 3pm 3.15pm - Afternoon Break (Tea/Coffee)

6 Session 7: Precision Based Medicine in the Clinic Chair: Laura Bennett (CRUK Manchester Institute) 3.15pm 3.30pm Alice Lallo (CRUK Manchester Institute) Title: Ex Vivo Culture of Circulating Tumor Cell Derived Explants to Facilitate Rapid Therapy Testing in SCLC 3.30pm 4.00pm Confirmed Lecture Title: Personalized treatments in lung cancer: EGFR, ALK and beyond Speaker: Professor Siow-Ming Lee (University College Hospital) 4.00pm 4.15pm Prize-Giving Presentations and Closing Remarks 4.15pm Close