SpringerBriefs in Cancer Research
|
|
- Junior Moore
- 6 years ago
- Views:
Transcription
1 SpringerBriefs in Cancer Research For further volumes:
2
3 Natalia Aptsiauri Angel Miguel Garcia-Lora Teresa Cabrera MHC Class I Antigens In Malignant Cells Immune Escape and Response to Immunotherapy
4 Natalia Aptsiauri Servicio de Análisis Clínicos Hosp. Universitario Virgen de las Nieves Granada, Spain Angel Miguel Garcia-Lora Servicio de Análisis Clínicos Hosp. Universitario Virgen de las Nieves Granada, Spain Teresa Cabrera Departamento de Bioquímica y Biología Molecular III e Inmunología Universidad de Granada Granada, Spain ISBN ISBN (ebook) DOI / Springer New York Heidelberg Dordrecht London Library of Congress Control Number: Teresa Cabrera 2013 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, speci fi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on micro fi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied speci fi cally for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a speci fi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (
5 Acknowledgments We would like to thank David Diez Cabrera a professional artist for the fi gures. We would also like to acknowledge all the contributions of the students and investigators who have been part of the large research group at the Department of Clinical Analysis at the Virgen de las Nieves University Hospital in Granada, Spain. This work has been supported over the years by grants from the Fondo de Investigaciones Sanitarias (FIS), Red Genomica del Cancer (RETIC), Plan Andaluz de Investigación (Group CTS-143), Servicio Andaluz de Salud (SAS), Plan Nacional de Investigación Cientí fi ca, Desarrollo e Innovación Tecnológica (Proyectos SAF , and SAF ) in Spain; and from different European projects. v
6
7 Contents 1 Overview of MHC Class I Antigens... 1 MHC Class I Genes and Molecules... 1 MHC Class I Antigen Processing, Transport, and Assembly... 2 The Role of MHC Antigens in T- and NK-Cell-Mediated Immunity... 4 Mechanisms of Cancer Immune Escape... 5 References HLA Class I Expression in Human Cancer Altered HLA Class I Expression in Malignant Cells Difficulties to Define HLA Class I Altered Phenotypes in Tumor Tissue Reversible and Irreversible Molecular Defects Underlying Altered Expression of HLA Class I Antigens on Tumor Cells Reversible Defects Irreversible Alterations Correlation Between HLA Class I Defects and Cancer Progression in Humans Role of HLA Class I Altered Expression in Resistance to Immunotherapy HLA and Resistance to Immunotherapy in Melanoma and Bladder Cancer References MHC Class I Expression in Experimental Mouse Models of Cancer: Immunotherapy of Tumors with Different MHC-I Expression Patterns Immunotherapy of Primary Tumors with Different Levels of MHC-I Expression Immunotherapy Against Metastases Derived from Primary Tumors with Different MHC-I Cell Surface Expression vii
8 viii Contents Immunotherapy Used as Anti-metastatic Treatment in a Murine Tumor Model Composed of Several Clones with Different MHC-I Expression GR9 Murine Tumor Model In Vivo Local Growth and Metastatic Capacity of the Studied Fibrosarcoma Clones Immunotherapy as Anti-metastatic Treatment of A7 Fibrosarcoma Clone with High Level of MHC-I Expression Immunotherapy as Anti-metastatic Treatment of B7 Clone with an Intermediate Level of MHC-I Expression Immunotherapy as Anti-metastatic Treatment Against Metastatic Colonization Generated from GR9 Fibrosarcoma Cells Chapter Summary References Potential Therapeutic Approaches for Increasing Tumor Immunogenicity by Upregulation of Tumor HLA Class I Expression References Conclusions... 51
SPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY. Gerhard Bauer Joseph S. Anderson. Gene Therapy for HIV From Inception to a Possible Cure
SPRINGER BRIEFS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY Gerhard Bauer Joseph S. Anderson Gene Therapy for HIV From Inception to a Possible Cure 123 SpringerBriefs in Biochemistry and Molecular Biology For
More informationMark W.J. Strachan Brian M. Frier. Insulin Therapy. A Pocket Guide
Insulin Therapy Mark W.J. Strachan Brian M. Frier Insulin Therapy A Pocket Guide Mark W.J. Strachan, MD, FRCP (Ed) Metabolic Unit Western General Hospital Edinburgh United Kingdom Brian M. Frier, MD,
More informationProgress in Social Psychiatry in Japan
Progress in Social Psychiatry in Japan Yoshibumi Nakane Progress in Social Psychiatry in Japan An Approach to Psychiatric Epidemiology Yoshibumi Nakane Department of Neuropsychiatry Nagasaki University
More informationAlexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov. Breast Ultrasound
Breast Ultrasound Alexander N. Sencha Elena V. Evseeva Mikhail S. Mogutov Yury N. Patrunov Breast Ultrasound Alexander N. Sencha Department of Ultrasound Diagnostics Yaroslavl Railway Clinic Yaroslavl
More informationCongenital Hip Disease in Adults
Congenital Hip Disease in Adults George Hartofilakidis George C. Babis Kalliopi Lampropoulou-Adamidou Congenital Hip Disease in Adults George Hartofilakidis, MD, FACS Orthopaedic Department Medical School
More informationWhite Coat Hypertension
White Coat Hypertension Giuseppe Mancia Guido Grassi Gianfranco Parati Alberto Zanchetti White Coat Hypertension An Unresolved Diagnostic and Therapeutic Problem Giuseppe Mancia Emeritus Professor University
More informationDifferential Diagnosis of Movement Disorders in Clinical Practice
Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Peter Hedera Differential Diagnosis of Movement Disorders in Clinical Practice Abdul Qayyum Rana Parkinson's Clinic
More informationProgressive Multiple Sclerosis
Progressive Multiple Sclerosis Alastair Wilkins Editor Progressive Multiple Sclerosis Editor Alastair Wilkins, M.A., M.B., B.Chir, Ph.D., FRCP Department of Neurology Frenchay Hospital Bristol UK ISBN
More informationEvidence-Based Forensic Dentistry
Evidence-Based Forensic Dentistry Balwant Rai Jasdeep Kaur Evidence-Based Forensic Dentistry Authors Balwant Rai Earth and Life Sciences Vrije Universiteit Amsterdam and ILEWG Amsterdam The Netherlands
More informationNeurobiological Bases of Abnormal Aggression and Violent Behaviour
Neurobiological Bases of Abnormal Aggression and Violent Behaviour . József Haller Neurobiological Bases of Abnormal Aggression and Violent Behaviour József Haller Department of Behavioral Neurobiology
More informationAtlas of Lymph Node Anatomy
Atlas of Lymph Node Anatomy Mukesh G. Harisinghani Editor Atlas of Lymph Node Anatomy This publication was developed through an unrestricted educational grant from Siemens. Editor Mukesh G. Harisinghani
More informationDiseases of the Spinal Cord
Diseases of the Spinal Cord Elke Hattingen Stefan Weidauer Matthias Setzer Johannes C. Klein Frank Vrionis Editors Diseases of the Spinal Cord Novel Imaging, Diagnosis and Treatment Editors Elke Hattingen
More informationAdvancing Responsible Adolescent Development
Advancing Responsible Adolescent Development Series Editor Roger J.R. Levesque For additional volumes: http://www.springer.com/series/7284 wwwwwwwwww Anna-Karin Andershed Editor Girls at Risk Swedish Longitudinal
More informationCerebral Blood Flow, Metabolism, and Head Trauma
Cerebral Blood Flow, Metabolism, and Head Trauma Christian W. Kreipke Editors Jose A. Rafols Cerebral Blood Flow, Metabolism, and Head Trauma The Pathotrajectory of Traumatic Brain Injury Editors Christian
More informationHuman Motivation and Interpersonal Relationships
Human Motivation and Interpersonal Relationships Netta Weinstein Editor Human Motivation and Interpersonal Relationships Theory, Research, and Applications Editor Netta Weinstein Department of Psychology
More informationMusculoskeletal Health in Women
Musculoskeletal Health in Women Elinor Mody Elizabeth Matzkin Editors Musculoskeletal Health in Women Editors Elinor Mody, MD Department of Rheumatology Gretchen and Edward Fish Center for Women s Health
More informationRadiology Illustrated
Radiology Illustrated For further volumes: http://www.springer.com/series/11755 In-One Kim Editor Radiology Illustrated: Pediatric Radiology Editor In-One Kim, M.D. Department of Radiology Seoul National
More informationEmerging Concepts of Tumor Exosome Mediated Cell Cell Communication
Emerging Concepts of Tumor Exosome Mediated Cell Cell Communication Huang-Ge Zhang Editor Emerging Concepts of Tumor Exosome Mediated Cell Cell Communication 2123 Editor Huang-Ge Zhang University of Louisville
More informationRadiation Therapy for Skin Cancer
Radiation Therapy for Skin Cancer Armand B. Cognetta Jr. William M. Mendenhall Editors Radiation Therapy for Skin Cancer Editors Armand B. Cognetta Jr. Dermatology Associates of Tallahassee Chief, Division
More informationJohn Papadopoulos David R. Schwartz Consulting Editor. Pocket Guide to Critical Care Pharmacotherapy Second Edition
John Papadopoulos David R. Schwartz Consulting Editor Pocket Guide to Critical Care Pharmacotherapy Second Edition 123 Pocket Guide to Critical Care Pharmacotherapy John Papadopoulos Author David R. Schwartz
More informationTadaaki Kirita Ken Omura Editors. Oral Cancer. Diagnosis and Therapy
Oral Cancer Tadaaki Kirita Ken Omura Editors Oral Cancer Diagnosis and Therapy Editors Tadaaki Kirita Department of Oral and Maxillofacial Surgery Nara Medical University Nara, Japan Ken Omura Oral Cancer
More informationRespiratory Medicine Series Editor: Sharon I.S. Rounds. Marc A. Judson Editor. Pulmonary Sarcoidosis A Guide for the Practicing Clinician
Respiratory Medicine Series Editor: Sharon I.S. Rounds Marc A. Judson Editor Pulmonary Sarcoidosis A Guide for the Practicing Clinician Respiratory Medicine Series Editor: Sharon I.S. Rounds For further
More informationUrinary Tract Infection
Urinary Tract Infection Abhay Rané Ranan Dasgupta Editors Urinary Tract Infection Clinical Perspectives on Urinary Tract Infection Editors Abhay Rané, MS, FRCS, FRCS (Urol) Department of Urology Surrey
More informationEnd of Life Care in Neurological Disease
End of Life Care in Neurological Disease David Oliver Editor End of Life Care in Neurological Disease Editor David Oliver BSc FRCP FRCGP Wisdom Hospice Rochester Kent UK ISBN 978-0-85729-681-8 ISBN 978-0-85729-682-5
More informationMinimally Invasive Gynecological Surgery
Minimally Invasive Gynecological Surgery O l av Is t re Editor Minimally Invasive Gynecological Surgery Editor Olav Istre, MD, PhD Fredriksberg Denmark ISBN 978-3-662-44058-2 ISBN 978-3-662-44059-9 (ebook)
More informationMorbid Obesity in Adolescents
Morbid Obesity in Adolescents ThiS is a FM Blank Page Kurt Widhalm Gerhard Prager Editors Morbid Obesity in Adolescents Conservative Treatment and Surgical Approaches Editors Kurt Widhalm Department of
More informationCLINICAL GASTROENTEROLOGY
CLINICAL GASTROENTEROLOGY Series Editor George Y. Wu University of Connecticut Health Center, Farmington, CT, USA For further volumes: http://www.springer.com/series/7672 Elizabeth J. Carey Keith D. Lindor
More informationLocal Flaps in Facial Reconstruction
Local Flaps in Facial Reconstruction Velupillai Ilankovan Madan Ethunandan Tian Ee Seah Local Flaps in Facial Reconstruction A Defect Based Approach Velupillai Ilankovan Poole Hospital NHS Foundation
More informationThe Olfactory System
The Olfactory System Editor The Olfactory System From Odor Molecules to Motivational Behaviors Editor Department of Physiology The University of Tokyo Tokyo, Japan ISBN 978-4-431-54375-6 ISBN 978-4-431-54376-3
More informationImaging of Urinary Tract Diverticula
Imaging of Urinary Tract Diverticula Vladimir M. Builov Imaging of Urinary Tract Diverticula Vladimir M. Builov Department of X-Ray and MRI RailWay Clinical Hospital Yaroslavl Russia ISBN 978-3-319-05382-0
More informationNeural-Immune Interactions in Brain Function and Alcohol Related Disorders
Neural-Immune Interactions in Brain Function and Alcohol Related Disorders Changhai Cui Lindsey Grandison Antonio Noronha Editors Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
More informationReconstructive Oral and Maxillofacial Surgery
Reconstructive Oral and Maxillofacial Surgery Carlos Navarro Vila Editor Reconstructive Oral and Maxillofacial Surgery Editor Carlos Navarro Vila Hospital General Universitario Gregorio Marañón Madrid
More informationDeep Brain Stimulation for Neurological Disorders
Deep Brain Stimulation for Neurological Disorders Toru I t a k u ra Editor Deep Brain Stimulation for Neurological Disorders Theoretical Background and Clinical Application Editor Toru Itakura, MD, PhD
More informationMorphological Aspects of Inner Ear Disease
Morphological Aspects of Inner Ear Disease Yasuya Nomura Morphological Aspects of Inner Ear Disease Yasuya Nomura President The Society for Promotion of International Oto-Rhino-Laryngology Tokyo, Japan
More informationRadiation Therapy for Head and Neck Cancers
Radiation Therapy for Head and Neck Cancers Murat Beyzadeoglu Gokhan Ozyigit Ugur Selek Editors Radiation Therapy for Head and Neck Cancers A Case-Based Review Editors Murat Beyzadeoglu, MD Professor
More informationThomas Reinhard Frank Larkin Editors. Corneal Disease. Recent Developments in Diagnosis and Therapy
Corneal Disease Thomas Reinhard Frank Larkin Editors Corneal Disease Recent Developments in Diagnosis and Therapy Editors Prof. Dr. med. Thomas Reinhard University Eye Hospital Freiburg Germany Dr. Frank
More informationFundamentals of Cancer Prevention
Fundamentals of Cancer Prevention David Alberts Lisa M. Hess Editors Fundamentals of Cancer Prevention Third Edition Editors David Alberts College of Medicine Arizona Cancer Center University of Arizona
More informationImaging of Alimentary Tract Perforation
Imaging of Alimentary Tract Perforation Luigia Romano Antonio Pinto Editors Imaging of Alimentary Tract Perforation Editors Luigia Romano Department of Radiology A. Cardarelli Hospital Naples Italy Antonio
More informationMitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy
Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy Dhyan Chandra Editor Mitochondria as Targets for Phytochemicals in Cancer Prevention and Therapy 1 3 Editor Dhyan Chandra, Associate
More informationIndirect Questioning in Sample Surveys
Indirect Questioning in Sample Surveys Arijit Chaudhuri Tasos C. Christofides Indirect Questioning in Sample Surveys 123 Arijit Chaudhuri Applied Statistics Unit Indian Statistical Institute Kolkata,
More informationPlanning and Care for Children and Adolescents with Dental Enamel Defects
Planning and Care for Children and Adolescents with Dental Enamel Defects Etiology, Research and Contemporary Management Bernadette K. Drummond Nicola Kilpatrick Editors 123 Planning and Care for Children
More informationAtlas of Peripheral Nerve Ultrasound
Atlas of Peripheral Nerve Ultrasound Siegfried Peer Hannes Gruber Editors Atlas of Peripheral Nerve Ultrasound With Anatomic and MRI Correlation Editors Siegfried Peer CTI GesmbH Klostergasse 4 Innsbruck
More informationThe Cleveland Clinic Manual of Dynamic Endocrine Testing
The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin A. Laurence Kennedy Manjula K. Gupta Amir H. Hamrahian The Manual of Dynamic Endocrine Testing Ahmet Bahadir Ergin Department of Endocrinology,
More informationRecurrent Erosion Syndrome and Epithelial Edema
Recurrent Erosion Syndrome and Epithelial Edema Helena M. Tabery Recurrent Erosion Syndrome and Epithelial Edema In Vivo Morphology in the Human Cornea Helena M. Tabery, MD Malmö Sweden helena.tabery@telia.com
More informationThe Mediterranean Diet
The Mediterranean Diet wwwwwwwwwwwwww Eric Zacharias, M.D. The Mediterranean Diet A Clinician s Guide for Patient Care Eric Zacharias, M.D. Chairman, Department of Medicine, Boulder Medical Center Assistant
More informationMedication-Related Osteonecrosis of the Jaws
Medication-Related Osteonecrosis of the Jaws Sve n O t to Editor Medication-Related Osteonecrosis of the Jaws Bisphosphonates, Denosumab, and New Agents Editor Sven Otto, MD, DMD, FEBOMFS Department of
More informationGynecologic Oncology
Gynecologic Oncology Ramez N. Eskander Robert E. Bristow Editors Gynecologic Oncology A Pocketbook Editors Ramez N. Eskander, M.D. Assistant Professor Division of Gynecologic Oncology Department of Obstetrics
More informationEvidence Based Treatments for Trauma- Related Psychological Disorders
Evidence Based Treatments for Trauma- Related Psychological Disorders Ulrich Schnyder Marylène Cloitre Editors Evidence Based Treatments for Trauma-Related Psychological Disorders A Practical Guide for
More informationHealth-Related Quality of Life in Cardiovascular Patients
Health-Related Quality of Life in Cardiovascular Patients Kalina Kawecka-Jaszcz Marek Klocek Beata Tobiasz-Adamczyk Christopher J. Bulpitt Editors Health-Related Quality of Life in Cardiovascular Patients
More informationAutism and the Brain
Autism and the Brain Tatyana B. Glezerman Autism and the Brain Neurophenomenological Interpretation Tatyana B. Glezerman Independent Practitioner New York, NY, USA ISBN 978-1-4614-4111-3 ISBN 978-1-4614-4112-0
More informationSine Syndromes in Rheumatology
Sine Syndromes in Rheumatology Jozef Rovenský Manfred Herold Martina Vašáková Editors Sine Syndromes in Rheumatology Editors Jozef Rovenský National Institute of Rheumatic Diseases Piešťany Slovakia Institute
More informationInflammation and Lung Cancer
Inflammation and Lung Cancer Steven M. Dubinett Editor Inflammation and Lung Cancer 1 3 Editor Steven M. Dubinett David Geffen School of Medicine at UCLA Los Angeles California USA ISBN 978-1-4939-2723-4
More informationTherapeutic rtms in Neurology
Therapeutic rtms in Neurology Thomas Platz Editor Therapeutic rtms in Neurology Principles, Evidence, and Practice Recommendations Editor Thomas Platz BDH-Klinik Greifswald Ernst-Moritz-Arndt Universität
More informationApplications. in Oncology
Kewal K. Jain Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Applications of Biotechnology in Oncology Kewal K. Jain, MD, FRACS, FFPM Jain PharmaBiotech, Basel, Switzerland
More informationHepatitis C Virus and Liver Transplantation
Hepatitis C Virus and Liver Transplantation Marina Berenguer Editor Hepatitis C Virus and Liver Transplantation 2123 Editor Marina Berenguer, MD Department of Hepatology and Liver Transplantation La Fe
More informationCounseling and Action
Counseling and Action Richard A. Young José F. Domene Ladislav Valach Editors Counseling and Action Toward Life-Enhancing Work, Relationships, and Identity 1 3 Editors Richard A. Young Department of Educational
More informationThe Cardiac Lymphatic System
The Cardiac Lymphatic System Ganga Karunamuni Editor The Cardiac Lymphatic System An Overview Editor Ganga Karunamuni Department of Pediatrics Case Western Reserve University Cleveland, OH, USA ISBN 978-1-4614-6773-1
More informationIn Clinical Practice
In Clinical Practice Taking a practical approach to clinical medicine, this series of smaller reference books is designed for the trainee physician, primary care physician, nurse practitioner and other
More informationIatrogenic Effects of Orthodontic Treatment
Iatrogenic Effects of Orthodontic Treatment Roberto Justus Iatrogenic Effects of Orthodontic Treatment Decision-Making in Prevention, Diagnosis, and Treatment Roberto Justus Department of Orthodontics
More informationPulmonary Manifestations of Rheumatic Disease
Pulmonary Manifestations of Rheumatic Disease Paul F. Dellaripa Aryeh Fischer Kevin R. Flaherty Editors Pulmonary Manifestations of Rheumatic Disease A Comprehensive Guide With 64 Figures, 26 in Color
More informationSPRINGER HANDBOOK OF AUDITORY RESEARCH
SPRINGER HANDBOOK OF AUDITORY RESEARCH Series Editors: Richard R. Fay and Arthur N. Popper Sunil Puria Richard R. Fay Arthur N. Popper Editors The Middle Ear Science, Otosurgery, and Technology Springer
More informationEsthetic and Functional Management of Diastema
Esthetic and Functional Management of Diastema Ugur Erdemir Esra Yildiz Editors Esthetic and Functional Management of Diastema A Multidisciplinary Approach Editors Ugur Erdemir Faculty of Dentistry University
More informationMeasures of Positive Psychology
Measures of Positive Psychology Kamlesh Singh Mohita Junnarkar Jasleen Kaur Measures of Positive Psychology Development and Validation 123 Kamlesh Singh Department of Humanities and Social Sciences Indian
More informationLouise Grech Alan Lau Editors. Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis. From Hospital to Community
Louise Grech Alan Lau Editors Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis From Hospital to Community Pharmaceutical Care Issues of Patients with Rheumatoid Arthritis Louise Grech
More informationPractical Case Studies in Hypertension Management. Series editor Giuliano Tocci Rome, Italy
Practical Case Studies in Hypertension Management Series editor Giuliano Tocci Rome, Italy The aim of the book series Practical Case Studies in Hypertension Management is to provide physicians who treat
More informationLow and Lower Fertility
Low and Lower Fertility Ronald R. Rindfuss Minja Kim Choe Editors Low and Lower Fertility Variations across Developed Countries Editors Ronald R. Rindfuss Department of Sociology and Carolina Population
More informationOsteoarthritic Knee Joint Painted by Artist: Mika Katsuta (Japan)
Osteoarthritis Osteoarthritic Knee Joint Painted by Artist: Mika Katsuta (Japan) Mohit Kapoor Nizar N. Mahomed Editors Osteoarthritis Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative
More informationWound Management in Urgent Care
Wound Management in Urgent Care Brittany Busse Wound Management in Urgent Care Brittany Busse, MD Med 7 Urgent Care Folsom, CA, USA ISBN 978-3-319-27426-3 DOI 10.1007/978-3-319-27428-7 ISBN 978-3-319-27428-7
More informationCell and Molecular Biology of Breast Cancer
Cell and Molecular Biology of Breast Cancer Heide Schatten Editor Cell and Molecular Biology of Breast Cancer Editor Heide Schatten Department of Veterinary Pathobiology University of Missouri-Columbia
More informationSuicide: Phenomenology and Neurobiology
Suicide: Phenomenology and Neurobiology Keri E. Cannon Thomas J. Hudzik Editors Suicide: Phenomenology and Neurobiology 123 Editors Keri E. Cannon Global Safety Pharmacology Pfizer, Inc. Groton, CT USA
More informationThe Training Courses of Urological Laparoscopy
The Training Courses of Urological Laparoscopy Ying Hao Sun Arthur D. Smith Editors The Training Courses of Urological Laparoscopy Editors Ying Hao Sun, M.D. Department of Urology Changhai Hospital Shanghai
More informationRadiation Therapy for Gastrointestinal Cancers
Radiation Therapy for Gastrointestinal Cancers Theodore Hong Prajnan Das Editors Radiation Therapy for Gastrointestinal Cancers Editors Theodore Hong Massachusetts General Hospital Harvard Medical School
More informationOffice-Based Gynecologic Surgical Procedures
Office-Based Gynecologic Surgical Procedures Jonathan D. Emery Marie Fidela R. Paraiso Editors Office-Based Gynecologic Surgical Procedures Editors Jonathan D. Emery, M.D. Department of Obstetrics and
More informationIntraductal Papillary Mucinous Neoplasm of the Pancreas. Masao Tanaka Editor
Intraductal Papillary Mucinous Neoplasm of the Pancreas Masao Tanaka Editor Intraductal Papillary Mucinous Neoplasm of the Pancreas Masao Tanaka Editor Intraductal Papillary Mucinous Neoplasm of the Pancreas
More informationSpringerBriefs in Psychology. Series Editors Daniel David Raymond A. DiGiuseppe Kristene A. Doyle
SpringerBriefs in Psychology Series Editors Daniel David Raymond A. DiGiuseppe Kristene A. Doyle Epidemiological studies show that the prevalence of mental disorders is extremely high across the globe
More informationUreteral Stone Management
Ureteral Stone Management Sutchin R. Patel Stephen Y. Nakada Editors Ureteral Stone Management A Practical Approach Editors Sutchin R. Patel Department of Urology University of Wisconsin School of Medicine
More informationPractical Case Studies in Hypertension Management. Series editor: Giuliano Tocci Rome Italy
Practical Case Studies in Hypertension Management Series editor: Giuliano Tocci Rome Italy The aim of the book series Practical Case Studies in Hypertension Management is to provide physicians who treat
More informationSpringerBriefs in Applied Sciences and Technology
SpringerBriefs in Applied Sciences and Technology Computational Intelligence Series Editor Janusz Kacprzyk, Systems Research Institute, Polish Academy of Sciences, Warsaw, Poland SpringerBriefs in Computational
More informationRobotic Cardiac Surgery
Robotic Cardiac Surgery Changqing Gao Editor Robotic Cardiac Surgery Editor Changqing Gao, MD Department of Cardiovascular Surgery PLA General Hospital Beijing Peoples s Republic of China ISBN 978-94-007-7659-3
More informationGenetic Influences on Response to Drug Treatment for Major Psychiatric Disorders
Genetic Influences on Response to Drug Treatment for Major Psychiatric Disorders Janusz K. Rybakowski Alessandro Serretti Editors Genetic Influences on Response to Drug Treatment for Major Psychiatric
More informationBenign Breast Diseases
Catherine N. Chinyama Benign Breast Diseases Radiology Pathology Risk Assessment Second Edition 123 Benign Breast Diseases Catherine N. Chinyama Benign Breast Diseases Radiology - Pathology - Risk Assessment
More informationMedical Management of the Pregnant Patient
Medical Management of the Pregnant Patient Karen Rosene-Montella Editor Medical Management of the Pregnant Patient A Clinician s Handbook Editor Karen Rosene-Montella, MD SVP Women s Services and Clinical
More informationThe Role of Bacteria in Urology
The Role of Bacteria in Urology Dirk Lange Ben Chew Editors The Role of Bacteria in Urology Editors Dirk Lange Basic Science Research The Stone Centre at Vancouver General Hospital Vancouver British Columbia
More informationFrozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA
Frozen Section Library Series Editor Philip T. Cagle, MD Houston, Texas, USA For further volumes, go to http://www.springer.com/series/7869 Frozen Section Library: Central Nervous System Richard A. Prayson
More informationPediatric Endodontics
Pediatric Endodontics Anna B. Fuks Benjamin Peretz Editors Pediatric Endodontics Current Concepts in Pulp Therapy for Primary and Young Permanent Teeth Editors Anna B. Fuks Department of Pediatric Dentistry
More informationPhytochemicals, Signal Transduction, and Neurological Disorders
Phytochemicals, Signal Transduction, and Neurological Disorders Akhlaq A. Farooqui Phytochemicals, Signal Transduction, and Neurological Disorders Akhlaq A. Farooqui Department of Molecular and Cellular
More informationAngiogenesis Modulations in Health and Disease
Angiogenesis Modulations in Health and Disease Shaker A. Mousa Paul J. Davis Editors Angiogenesis Modulations in Health and Disease Practical Applications of Pro- and Anti-angiogenesis Targets Editors
More informationThe Many Faces of Social Attention
The Many Faces of Social Attention Aina Puce Bennett I. Bertenthal Editors The Many Faces of Social Attention Behavioral and Neural Measures 1 3 Editors Aina Puce Psychological and Brain Sciences Indiana
More informationCurrent Clinical Urology
Current Clinical Urology Eric A. Klein, MD, Series Editor For further volumes: http://www.springer.com/series/7635 Urological Men s Health A Guide for Urologists and Primary Care Physicians Editor Daniel
More informationKostas N. Fountoulakis. Bipolar Disorder. An Evidence-Based Guide to Manic Depression
Kostas N. Fountoulakis Bipolar Disorder An Evidence-Based Guide to Manic Depression 123 Bipolar Disorder Kostas N. Fountoulakis Bipolar Disorder An Evidence-Based Guide to Manic Depression Kostas N. Fountoulakis
More informationSami Shousha Editor. Breast Pathology. Problematic Issues
Breast Pathology Editor Breast Pathology Problematic Issues Editor Charing Cross Hospital Imperial College Healthcare NHS Trust & Imperial College London United Kingdom ISBN 978-3-319-28653-2 ISBN 978-3-319-28655-6
More informationSpringerBriefs in Criminology
SpringerBriefs in Criminology Policing Series editor M.R. Haberfeld City University of New York John Jay College of Criminal Justice New York, NY, USA More information about this series at http://www.springer.com/series/11179
More informationHandbook of Insulin Therapies
Handbook of Insulin Therapies Winston Crasto Janet Jarvis Melanie J. Davies Handbook of Insulin Therapies Winston Crasto George Eliot Hospital NHS Trust, Nuneaton United Kingdom Janet Jarvis Leicester
More informationMedical and Surgical Complications of Sickle Cell Anemia
Medical and Surgical Complications of Sickle Cell Anemia Ahmed Al-Salem Medical and Surgical Complications of Sickle Cell Anemia Ahmed Al-Salem Department of Surgery Dar A lalafia Medical Company Qatif
More informationCancer Treatment and Research
Cancer Treatment and Research Volume 155 Series Editor Steven T. Rosen For further volumes: http://www.springer.com/series/5808 Boris Pasche Editor Cancer Genetics 123 Editor Boris Pasche, MD, PhD, FACP
More informationSabine Bährer-Kohler. Editor. Burnout for Experts. Prevention in the Context of Living and Working
Burnout for Experts Sabine Bährer-Kohler Editor Burnout for Experts Prevention in the Context of Living and Working Editor Sabine Bährer-Kohler Dr. Bährer-Kohler & Partners PO Box 3244 Peter-Merian-Str.
More informationErin Lawson Mark S. Wallace Editors. Fibromyalgia. Clinical Guidelines and Treatments
Fibromyalgia Erin Lawson Mark S. Wallace Editors Fibromyalgia Clinical Guidelines and Treatments Editors Erin Lawson, MD Voluntary Faculty Department of Anesthesiology Center for Pain Medicine University
More informationUrogynecology: Evidence-Based Clinical Practice
Urogynecology: Evidence-Based Clinical Practice Kate H. Moore Urogynecology: Evidence-Based Clinical Practice Second Edition Kate H. Moore, MBBS, FRCOG, FRANZCOG, MD, CU Department Obstetrics & Gynaecology
More informationManagement of Post-Stroke Complications
Management of Post-Stroke Complications Ajay Bhalla Jonathan Birns Editors Management of Post-Stroke Complications Editors Ajay Bhalla Department of Ageing and Health Guy s and St Thomas NHS Foundation
More information