4-6 October Buenos Aires, Argentina

Transcription

1 PRACTICE TEACHING COURSE FINAL PROGRAMME Practice teaching course in head and neck cancer management 4-6 October Buenos Aires, Argentina

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3 GENERAL INFORMATION GENERAL INFO

4 Practice teaching course in head and neck cancer management Overview Surgery, radiation, and chemotherapy remain the primary treatment modalities for patients affected by head and neck squamous cell carcinoma. major advances in this disease have been made in the development of newer technologies, such as in radiation therapy, whether by intensity-modulated radiation therapy (IMRT) or proton-beam therapy. There have also been significant advances in the surgical treatment of head and neck cancer and in reconstructive methods, allowing our patients improvements in quality-of-life. Treatments are intensive, and thus are associated with significant acute and late toxicities. As treatments have become more effective, survivorship and long-term quality of life have gained particular relevance. Aim of the course is to provide an overview of current evidence and management, recent developments, and insights into future directions for the management of head and neck squamous cell carcinoma. Learning objectives After attending this course participants will be able to: Recognize rationale and benefits of working in a multidisciplinary team Summarize current treatment options for head and neck squamous cell carcinoma Critically review future trends in the management of and neck squamous cell carcinoma Target audience This course is meant for specialists with an experience in the management of head and neck cancer patients, including surgical, medical and radiation oncologists. Chairs Raúl Eduardo Giglio Oncology unit for head and neck cancer Hopital Ángel H. Roffo Buenos Aires, Argentina Jordi Giralt Radiation Oncology unit Vall d Hebron University Hospital Barcelona, Spain EXCEMED designed this programme in partnership with Prova Education. 4

5 CME Provider EXCEMED is a non profit foundation dedicated, since the last four decades, to the development of high-quality medical education programmes all over the world. EXCEMED adheres to the guidelines and standards of the European Accreditation Council for Continuing Medical Education (EACCME ) which states that continuing medical education must be balanced, independent, objective, and scientifically rigorous. Continuing medical education EXCEMED ( is accredited by the European Accreditation Council for Continuing Medical Education (EACCME ) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS), The CME Practice teaching course in head and neck cancer management held on 4-6 October 2017 in Buenos Aires, Argentina, is designated for a maximum of 16 (sixteen) hours of European CME credits (ECMEC). Each medical specialist should claim only those credits that he/she actually spent in the educational activity. EACCME credits are recognized by the American Medical Association (AMA) towards the Physician's Recognition Award (PRA). To convert EACCME credit to AMA PRA category 1 credit, please contact the AMA. EXCEMED adheres to the principles of the Good CME Practice group (gcmep). 5

6 Venue This live educational course takes place at: Hopital Ángel H. Roffo Av. San Martín 5481 Buenos Aires, Argentina Language The official language of this live educational course is English. CME Provider EXCEMED - Excellence in Medical Education Programme Manager: Silvia Cristofanelli T F silvia.cristofanelli@excemed.org Medical Advisor: Cristina Raimondi cristina.raimondi@libero.it For any logistic inquiry, please contact: Meridiano Congress International Senior Project Manager: Federica Russetti T F federica.russetti@meridiano.it 6

7 Format This live educational educational event is allowing participants to express their own views and opinions through interactive workshops with clinical cases, panel discussions, real-time surveys with voting system, questions cards and dedicated website. Dedicated website Access the dedicated website... to: Xxx xxx Xxx xxx Xxx xxx Xxx xxx Mobile application Download the conference application... and enjoy easy access to: Xxx xxx Xxx xxx Xxx xxx Xxx xxx Any question? You can pose your question by using the question card in your folder Xxx xxx Xxx xxx Xxx xxx 7

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9 FACULTY FACULTY

10 Faculty Roque Adan Chief Head and Neck Cancer Surgery Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Barbara Berenstein Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Nicolás Bustos Radiologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Juan Manuel Carrera Medical Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Celeste Diaz Medical Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Emiliano Garayalde Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Raúl Eduardo Giglio Head Medical Oncology Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina 10

11 Jordi Giralt Radiation Oncology unit Vall d Hebron University Hospital Barcelona, Spain Mauricio Jaciansky Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Marcos David Pereira Medical and Radiation Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Gonzalo Zeballos ETN Specialist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina 11

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13 PROGRAMME PROGRAMME

14 Wednesday, 4 October Registration Welcome Lunch Opening and local welcome Session I HNSCC Overview L1: Oropharyngeal cancers R.E. Giglio L2: Larynx and hypopharyngeal cancers M. Jaciansky, G. Zeballos L3: Oral cavity cancers R. Adan Coffee Break Session II Multidisciplinary cancer care in HNSCC L4: Rationale, definitions and benefits of working in a multidisciplinary team M.D. Pereira L5: General principles of radiology N. Bustos L6: General principles of surgery E. Garayalde L7: General principles of radiotherapy M.D. Pereira L8: General principles of systemic therapies J.M. Carrera Sharing experience session B. Berestein End of the first day Legend: L : Lecture : Sharing experience : Clinical case : Keynote lecture : Journal club 14

15 Thursday, 5 October 2017 Session III Practical session MDT (multidisciplinary tumor board at Instituto Roffo) Outpatient clinic Lunch Session IV HNSCC Treatment L9: Current treatment options for locally advanced HNSCC (induction therapy, organ preservation, treatment combinations) R.E. Giglio L10: The future of personalised radiotherapy treatment for head and neck cancer J. Giralt Coffee break L11: Current treatment options for recurrent/metastatic HNSCC (first line treatment, second line treatment, immunotherapies) J.M. Carrera Clinical case discussion B.Berenstein - M. Jaciansky End of the second day 15

16 Friday, 6 October Keynote lecture Multidisciplinary management of head and neck cancer: First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer J. Giralt Session V Practical Session Second opinion MDT (multidisciplinary tumor board at Instituto Roffo) R. Adan, J.M. Carrera, R.E. Giglio, M. Jaciansky, M.D. Pereira Lunch Clinical trials for HNSCC opened at Instituto Roffo R.E. Giglio Journal club C. Diaz End of the live educational course 16

17 Faculty disclosures EXCEMED adheres to guidelines of the European Accreditation Council for Continuing Medical Education (EACCME ) and all other professional organizations, as applicable, which state that programmes awarding continuing education credits must be balanced, independent, objective and scientifically rigorous. Investigative and other uses for pharmaceutical agents, medical devices and other products (other than those uses indicated in approved product labeling/package insert for the product) may be presented in the programme (which may reflect clinical experience, the professional literature or other clinical sources known to the presenter). We ask all presenters to provide participants with information about relationships with pharmaceutical or medical equipment companies that may have relevance to their lectures. This policy is not intended to exclude faculty who have relationships with such companies; it is only intended to inform participants of any potential conflicts so that participants may form their own judgements, based on full disclosure of the facts. Further, all opinions and recommendations presented during the programme and all programme-related materials neither imply an endorsement nor a recommendation on the part of EXCEMED. All presentations represent solely the independent views of the presenters/authors. The following faculty provided information regarding significant commercial relationships and/or discussions of investigational or non-emea/fda approved (off-label) uses of drugs: Barbara Berenstein Declared no potential conflict of interest Juan Manuel Carrera Declared no potential conflict of interest Celeste Diaz Jordi Giralt Mauricio Jaciansky Declared no potential conflict of interest Declared no potential conflict of interest Declared no potential conflict of interest Marcos David Pereira Declared no potential conflict of interest Gonzalo Zeballos Declared no potential conflict of interest The following faculty have provided no information regarding significant relationship with commercial supporters and/or discussion of investigational or non-emea/fda approved (offlabel) uses of drugs as of 18 September Roque Adan Nicolás Bustos Emiliano Garayalde Raúl Eduardo Giglio 17

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19 BIOGRAPHIES BIOGRAPHIES

20 Roque Adan Chief Head and Neck Cancer Surgery Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Roque Adan is the chief of the head and neck cancer surgery unit at Roffo Hospital. He also works as chief surgeon in other hospitals such as the British Hospital of Buenos Aires and the Alexander Fleming Institute. Among other activities, he also collaborated as Associate Professor in surgical oncology at Buenos Aires University. 20

21 Barbara Berenstein Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Barbara Berenstein is a surgeon at Roffo Hospital in Buenos Aires. She is specialized in head and neck cancer surgery and general surgery. Dr. Berenstein also works at Alexander Fleming Institute. 21

22 Nicolás Bustos Radiologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Nicolás Bustos graduated at the University of Buenos Aires in 2009 and undertook a Fellowship in PET/CT Imaging at the Fundación Centro Diagnóstico Nuclear - CNEA in He currently serves as a radiologist at the Instituto Oncológico Roffo, where he is a member of the multidisciplinary Head and Neck cancer team. He furthermore works for other bodies such as the Instituto Alexander Fleming and the Fundación Centro Diagnóstico Nuclear. 22

23 Juan Manuel Carrera Medical Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Juan Manuel Carrera is a medical oncologists specialized in Head and Neck and Breast cancer. He currently works at Instituto de Oncologia Angel Roffo, where he also underwent his residency. He is now part of the Head and Neck multidisciplinary team and performs his work also in La Plata city. 23

24 Celeste Diaz Medical Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Celeste Diaz graduated at the University Of Buenos Aires School Of Medicine. She trained in Clinical Oncology at Angel H. Roffo University Hospital residency programme and then joined the Head and neck unit as an attending physician. Dr. Diaz also trained in evidence-based medicine, biostatistics and health technology assessment. She is the coordinator of the Health Technology Assessment area at National Cancer Institute of Argentina since She also participated in the 2016 World Cancer Leaders Summit as a selected Young Leader by the Union for International Cancer Control (UICC). 24

25 Emiliano Garayalde Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Emiliano Garayalde studied in Mendoza at the Universidad Nacional de Cuyo where he graduated in He later on attended the CEMIC University Institute in general surgery. Dr. Garayalde is currently a staff member of the Head and Neck Functional Unit of the Intituto de Oncologia Roffo in buenos Aires since

26 Raúl Eduardo Giglio Head Medical Oncology Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Raúl Eduardo Giglio was born In Buenos Aires, Argentina. He studied medicine at the University of Buenos Aires School of Medicine and graduated in He completed a residency on internal medicine ( ) and the Fellowship in clinical oncology ( ). He obtained both postgraduate specialties. Dr. Giglio became staff physician in the clinical oncology department of the Instituto de Oncología Ángel H. Roffo (1989). Currently, he works in the same institute as the Head of clinical oncology. 26

27 Jordi Giralt Radiation Oncology unit Vall d Hebron University Hospital Barcelona, Spain Jordi Giralt focused his clinical research on the treatment of head and neck cancer. He participated to clinical trials regarding different strategies for the treatment of H&N cancer such as postoperative radiochemotherapy (Bernier, NEJM), the use of cetuximab (Bonner, NEJM, Lanct Onc), simultaneous chemo-radiotherapy (Rischin, JCO) or the use of panitumumab (Giralt, Lancet Onc). He also worked on radiotherapy quality control procedures (Peters, JCO or Christiaens, Radioth Onc) and strategies to minimize toxicity have also been a topic of great interest. He furthermore contributed to different consensus and recommendations and in the organization of conferences, courses and congresses on head and neck cancer such as the International Conference Head and Neck Oncology. He is the author of about 80 peer-review articles, of which over 60% are focused on head and neck tumors. 27

28 Mauricio Jaciansky Head and Neck Surgeon Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Mauricio Jaciansky graduated from the Faculty of Medicine of the Northeastern National University in He later obtained the specialty in General Surgery at the Hospital J.R. Vidal in the province of Corrientes city in 2010 and then performed the specialty in Head and Neck Surgery obtaining the Title in Dr. Jaciansky is currently working at the Oncological Institute Angel H. Roffo in the Surgery Department of the Head and Neck cancer Unit. 28

29 Marcos David Pereira Medical and Radiation Oncologist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Marcos David Pereira is a Medical and Radiation Oncologist. He obtained his medical degree at the National University of La Plata, in Argentina and, after a brief time working in a basic research lab, he started his residency in Medical Oncology at the Angel Roffo Oncology Institute, a cancer centre of the National University of Buenos Aires. Having obtained his first medical speciality, he started his training in Radiation Oncology, in the same hospital, as a fellow associated to the National Commission of Atomic Energy. By that time he worked actively in the Boron Neutron Capture Therapy Program, an experimental form of radiotherapy for advanced melanoma. He has participated in several clinical trials related to melanoma and head and neck tumours. He is responsible of radiotherapy in the Units of Melanoma/Sarcoma, Head and Neck and Skin of the Angel Roffo Oncology Institute and works in the education areas of Internal Medicine of the School of Medicine of the University of Buenos Aires and the Medical and Radiation Oncology training systems. He is also a member of the Independent Ethics Committee at Roffo Institute. In his free time he is an amateur photographer and an enthusiastic world traveller. 29

30 Gonzalo Zeballos ETN Specialist Head and Neck Cancer Unit Instituto de Oncología Ángel H. Roffo Buenos Aires, Argentina Gonzalo Zeballos graduated at the faculty of medicine of the National University of Tucuman, Argentina in 2006 and completed his residency in Otorhinolaryngology (ENT) at the Hospital Francés de Buenos Aires. He is currently a member of the Head and Neck oncology team at Roffo Hospital in Buenos Aires and also works at Cèsar Milstein Hospital at the department of laryngology. Dr. Zeballos is specialized in the use of Laser equipment technology and operates in several other bodies and Hospitals in Buenos Aires. 30

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33 LEARNING OBJECTIVES LEARNING OBJECTIVES

34 Session I Overview on HNSCC R. Adan (Argentina), R.E. Giglio (Argentina), M. Jaciansky (Argentina), G. Zeballos (Argentina) Learning objectives: Recognize the complexity and heterogeneity of HNSCC and its clinical impact Describe trends in epidemiology and provide an overview of the diagnostic approach and staging of head and neck cancers Review management approaches for HNSCC based on anatomical location NOTES 34

35 Session II Multidisciplinary cancer care in HNSCC N. Bustos (Argentina), J.M. Carrera (Argentina), E. Garayalde (Argentina), M.D. Pereira (Argentina) Learning objectives: Define rationale, methods and benefits for patients in working as part of a multidisciplinary team Describe general principles of each treatment modality Radiology: determine current imaging modalities and recommendations on modality choice for each cancer subsite Surgery: define integration of therapy, assessment of resectability, primary tumor resection, margins, management of recurrence and surveillance. Radiotherapy: describe technical advances, radiation as primary and adjuvant treatment, palliative RT regimens Explain current available drugs and combinations and emerging options NOTES 35

36 Session IV HNSCC Treatment J.M. Carrera (Argentina), R.E. Giglio (Argentina), J. Giralt (Spain) Learning objectives: Review current multimodality treatment options for locally advanced HNSCC Describe the biological heterogeneity of HNSCC and its impact on the individualization of radiation therapy Acquire current treatment options for metastatic HNSCC (standard first line therapy, emerging options for second line treatment, immunotherapy) NOTES 36

37 KNL Keynote lecture J. Giralt (Spain) Learning objectives: Provide elements on the Delphi methodology Analyze methods and results of the First expert consensus using Delphi methodology from the Spanish Society for Head and Neck Cancer Evaluate possible alternative applications of the Delphi methodology in the research on HNSCC NOTES 37

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48 All EXCEMED programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of EXCEMED. This programme is supported by independent educational grants received from Merck KGaA, Darmstadt, Germany and Università Vita Salute San Raffaele, Milan, Italy. 48

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50 Improving the patient's life through medical education EXCEMED - Excellence in Medical Education 14, Rue du Rhône Geneva, Switzerland Copyright EXCEMED, All rights reserved.