WLH Tumor Frequencies between cohort enrollment and 31-Dec Below the Women Lifestyle and Health tumor frequencies are tabulated according to:

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1 WLH Tumor Frequencies between cohort enrollment and 31-Dec 2012 DESCRIPTION Below the Women Lifestyle and Health tumor frequencies are tabulated according to: Benign =171 (Cervix uteri) treated as not recorded =191 (non-melanoma skin cancer) treated as not recorded Tumors coded as benign (BEN=3) by the Swedish cancer register have been treated as not recorded Given the selections above only the 1st primary have been considered Only the 1st primary cases diagnosed after cohort enrollment and up to 31-Dec-211 are included in the tabulations below A 1st primary before enrollment censor the woman from further cancer events Information about emigration or death or other data sources have not been utilized Note: This presentation is intended for planning purposes only. Note: This is an update of the SAS program created earlier for data up to 31-Dec-2012 Pouran Almstedt, MEB - Karolinska Institutet 1/6 August 2014

2 WLH Tumor Frequencies between cohort enrollment and 31-Dec 2012 Malign 1st primary tumors after cohort enrollment up to 31Dec digit codes =191 (non-melanoma skin cancer) not considered Percent of -3 digits Frequency Total codes Count Frequency 170 Breast Malignant melanoma of skin Bronchus and trachea, and lung specified as primary Corpus uteri Ovary, Fallopian tube and broad ligament Brain and other parts of nervous system Large intestine, except rectum Rectum Other endocrine glands Other and unspecified sites Cervix uteri Lymph sarcoma and reticulosarcoma Kidney Bladder and other urinary organs Pancreas Thyroid gland Multiple myeloma (plasmocytoma) Stomach Biliary passages and of liver Acute chronic and lymphoblastic leukaemia Mycosis fungoides Connective tissue Uterus, unspecified Other and unspecified female genital organs Tongue Small intestine, including duodenum Hodgkin disease Other parts of mouth Oral mesopharynx Polycytemia vera Other, unspecified chronic myeloproliferative disease Oesophagus Pouran Almstedt, MEB - Karolinska Institutet 2/6 August 2014

3 Percent of -3 digits Frequency Total codes Count Frequency 202 Other forms of lymphoma (reticulosis) Haematopoietic system Malignant neoplasm of salivary gland Malignant neoplasm of bone (including jaw bone) Nose, nasal cavities, middle ear Lymphatic system Malignant neoplasm of floor of mouth Malignant neoplasm of nasopharynx Lip Malignant neoplasm of peritoneum Malignant neoplasm of larynx Malignant neoplasm of mediastinum Malignant neoplasm of other parts of uterus ===== ====== Pouran Almstedt, MEB - Karolinska Institutet 3/6 August 2014

4 Malign 1st primary tumors after cohort enrollment up to 31Dec2012-4digit codes Benign =171 (Cervix uteri) or =191 (non-melanoma skin cancer) not considered Malignant neoplasm of breast (left) Malignant neoplasm of breast (right) Malignant neoplasm of bronchus and lung Malignant neoplasm of ovary Cerebral meninges/malignant neoplasm of brain Malignant melanoma of lower limb, including hip Malignant neoplasm of rectosigmoid junction Lymph nodes of head, face and neck/lymph node, unspecified Secondary malignant neoplasm of liver Breast, unspecified Bålen, axill, ljumske, scapulareg, perineum Parathyroid gland Follicular/unspecified and other types of follicular NHL, unspecific T-cell/B-cell lymphoma. Sigmoid colon Overlapping lesion of breast Malignant neoplasm of bladder Malignant melanoma of upper limb, including shoulder Malignant neoplasm of colon (Caecum/Ascending colon) Malignant neoplasm of kidney (Unspecified) Malignant neoplasm of kidney, except renal pelvis Malignant melanoma of skin, unspecified Acute myeloid leukaemia Stomach, unspecified Chronic lymphocytic leukaemia Pituitary gland Liver cell carcinoma/intrahepatic bile duct carcinoma Malignant neoplasm of colon (Hepatic or Splenic flexure Colon, unspecified Appendix Anus, unspecified Spinal meninges/cerebral meninges Malignant neoplasm of colon (Descending colon) Pouran Almstedt, MEB - Karolinska Institutet 4/6 August 2014

5 Malign 1st primary tumors after cohort enrollment up to 31Dec2012-4digit codes Benign =171 (Cervix uteri) or =191 (non-melanoma skin cancer) not considered Central nervous system, unspecified/meninges, UNS Malignant neoplasm of gallbladder Abdomen/Ill-defined sites within the digestive system Cardia Malignant neoplasm of adrenal gland (Cortex/Medulla/Unspec Vulva, unspecified Connective and soft tissue of lower limb, including hip Tonsil, unspecified (Nos, faucial, palatine Body of stomach, Pyloric antrum Overlapping lesion of female genital organs Malignant neoplasm of breast (unknown side) Connective and soft tissue of thorax/abdomen/pelvix Malignant melanoma of scalp and neck Chronic myeloid leukaemia Malignant neoplasm of vagina Malignant neoplasm of small intestine; Jejunum/Ileum Labium majus/labium minus Malignant neoplasm of renal pelvis Malignant neoplasm of base of tongue Small intestine; unspecified Extrahepatic bile duct Malignant melanoma of other and unspecified parts of face Malignant neoplasm of eye and adnexa, eyball/ciliary body Non-Hodgkin's lymphoma, unspecified type Malignant mast cell tumour, Peripheral T-cell lymphoma, Malignant- neoplasm without specification Acute lymphoblastic leukaemia Essential (haemorrhagic) thrombocythaemia Border of tongue Tongue, unspecified Middle third of oesophagus Oesophagus, unspecified Acute monocytic leukaemia External lower lip (nos, lipstick area, vermilion border) Pouran Almstedt, MEB - Karolinska Institutet 5/6 August 2014

6 Malign 1st primary tumors after cohort enrollment up to 31Dec digit codes Benign =171 (Cervix uteri) or =191 (non-melanoma skin cancer) not considered Malignant neoplasm of parotid gland Major salivary gland (major) Nos Biliary tract, unspecified Pleura Malignant melanoma of ear and external auricular canal Endocrine pancreas Malignant neoplasm of bone (including jaw bone) - Lower limb, long bones Connective and soft tissue of trunk, unspecified Connective and soft tissue of upper limb,including shoulder Retroperitoneal rum Connective and soft tissue, unspecified Acute promyelocytic leukaemia, Acute myelomonocytic leuk Submandibular gland Malignant neoplasm of small intestine, including duodenum Duodenum Nasal cavity Malignant neoplasm of nasal cavity Malignant neoplasm of Middle ear Etmoidalsinus (Ethmoid holes) Nose s sinus paranasales unspecified Female genital organ, unspecified Urethra Overlapping malignant melanoma of skin Malignant neoplasm of eye Carotid body Mandible Malignant neoplasm of bone (including jaw bone) - Bones of the skull and face Connective and soft tissue of head, face and neck Malignant neoplasm of other and unspecified sites Malignant neoplasm of Pelvix Lymphosarcoma and reticulosarcoma Hairy-cell leukaemia Pouran Almstedt, MEB - Karolinska Institutet 6/6 August 2014

7 Malign 1st primary tumors after cohort enrollment up to 31Dec2012-4digit codes Benign =171 (Cervix uteri) or =191 (non-melanoma skin cancer) not considered Other lymphoid leukaemia Acute leukaemia of unspecified cell type ===== ===== Sum: Pouran Almstedt, MEB - Karolinska Institutet 7/6 August 2014

WLH Tumor Frequencies between cohort enrollment and 31-Dec Below the Women Lifestyle and Health tumor frequencies are tabulated according to:

WLH Tumor Frequencies between cohort enrollment and 31-Dec Below the Women Lifestyle and Health tumor frequencies are tabulated according to: DESCRIPTION Below the Women Lifestyle and Health tumor frequencies are tabulated according to: Benign =171 (Cervix uteri) treated as not recorded =191 (non-melanoma skin cancer) treated as not recorded

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