MEDICAL ONCOLOGY ESO-ESMO EASTERN EUROPE AND BALKAN REGION MASTERCLASS IN. 27 June - 2 July 2014 Brdo, Slovenia. Chairs: T. Cufer, SI R.

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1 Flyer MMO_(4 Mar)_screen :33 Pagina 3 MASTERCLASS ESO-ESMO EASTERN EUROPE AND BALKAN REGION MASTERCLASS IN MEDICAL ONCOLOGY 27 June - 2 July 2014 Brdo, Slovenia Chairs: R. Herrmann, CH

2 This residential programme has been designed for medical and clinical oncologists, who wish to improve their skills or those who are preparing for the national or ESMO board exam. The programme will expose participants to a full spectrum of issues in clinical and medical oncology from basic science to advanced knowledge of systemic therapy as well as in the multidisciplinary treatment approach. It is intended to cover all major topics of ESMO-ASCO curriculum on medical oncology. The programme focuses on cancer pathology and molecular biology, pharmacology of anti-cancer drugs and on frequent cancers such as breast, lung, gastro-intestinal, gynaecological and head and neck cancer. Spotlight sessions will provide inside on state of the art approaches in melanoma, sarcoma, thyroid cancer and on palliative care. Furthermore, practical training will be offered in the frame of clinical case presentations, prepared and presented by the participants and faculty for an interactive discussion. All participants will reside at the Masterclass venue and participation is mandatory throughout the course. At the end of each of the five days a learning selfassessment discussion with the chair of the course will be provided. Learning objectives To update the knowledge on basic science of clinical and medical oncology. To enhance the competence and practical performance in systemic therapy of malignancies. To enhance the competence and practical performance in multidisciplinary cancer care. To update knowledge and get additional skills in supportive as well as palliative care. To prepare for the board exam in clinical/medical oncology. The Masterclass is A 5-days residential educational event Full immersion Clinically oriented Multidisciplinary

3 FACULTY (as of 4 April 2014) J. Beyer University Hospital Zürich, CH R. Catane Sheba Medical Center, Tel -Hashomer, IL A. Celebic Clinical Center of Montenegro, Podgorica, ME G. Cserni Bacs Kiskun County Teaching Hospital, Kecskemet, HU T. Cufer University Clinic Golnik, SI A. Eniu Cancer Institute I. Chiricuta, Cluj-Napoca, RO R. Herrmann University Hospital, Basel, CH M. Joerger Cantonal Hospital St. Gallen, CH D. Jovanovic Clinical Center of Serbia, Belgrade, RS I. Kern University Clinic Golnik, SI F. Krasniqi University Hospital Basel, CH F. Lordick University Clinic Leipzig, DE E. Matos Institute of Oncology Ljubljana, SI G. Pentheroudakis University Hospital of Ioannina, GR R. Popescu Hirslanden Klinik Aarau, CH B. Šeruga Institute of Oncology Ljubljana, SI B. Sharma Royal Marsden, London, UK P. Strojan Institute of Oncology Ljubljana, SI T. Štupnik University Medical Center Ljubljana, SI E. Vrdoljak Clinical Hospital Split, HR B. Zakotnik Institute of Oncology Ljubljana, SI

4 PRELIMINARY PROGRAMME FRIDAY, 27 JUNE Participants arrivals SATURDAY, 28 JUNE 9:00 Welcome address and general introduction CANCER BIOLOGY/PATHOLOGY 9:30 Molecular biology of solid tumors Speaker to be confirmed 10:00 Molecular pathology and differential diagnostic of cancer of unknown primary G. Cserni, HU 10:30 Principles of genetic testing and counseling R. Catane, IL 11:00 Discussion 11:30 Coffee break 11:45 Spotlight lecture: Imaging in oncology B. Sharma, UK 12:30 Lunch break PHARMACOLOGY 13:30 Pharmacology and dosing of selected anticancer drugs M. Joerger, CH 14:00 Drug-drug interactions M. Joerger, CH 14:45 Discussion 15:15 Coffee break 15:30 Spotlight lecture: Targeted therapies of renal cell carcinoma E. Vrdoljak, HR 16:15 Spotlight lecture: New developments in systemic treatment of gynecological cancers E. Vrdoljak, HR

5 17:00 Spotlight lecture: Advances in systemic treatment of thyroid cancer G. Pentheroudakis, GR 17:45- Learning self- assessment discussion 18:15 R. Herrmann, CH SUNDAY, 29 JUNE BREAST CANCER 9:00 Breast cancer pathology and molecular biology G. Cserni, HU 9:30 Essentials of local therapy for breast cancer A. Celebic, ME 10:00 Optimal approach in locally advanced disease A. Eniu, RO 10:30 Coffee break 10:45 Systemic treatment of HR positive disease B. Seruga, SI 11:15 Systemic treatment of HER2-positive disease 11:45 Triple negative breast cancer A. Eniu, RO 12:15 Discussion 12:45 Lunch Break 14:00 Tumor board on Breast cancer 5 cases presented by participants and discussed by the panel 16:30 Coffee break 16:45 Spotlight lecture: Update on palliative care R. Catane, IL 17:30 Spotlight lecture: Advances in systemic treatment of melanoma Speaker to be confirmed 18:15- Learning self- assessment discussion 19:15 R. Herrmann, CH

6 MONDAY, 30 JUNE GASTRO-INTESTINAL TUMOURS 9:00 Management of esophageal cancer F. Lordick, DE 9:30 Systemic treatment in early and advanced gastric cancer F. Lordick, DE 10:00 Management of early and locally advanced colorectal cancer F. Lordick, DE 10:30 Coffee break 10:45 Systemic treatment of advanced colorectal cancer R. Popescu, CH 11:15 New developments in systemic treatment of hepatobiliary and pancreatic cancer R. Popescu, CH 11:45 Discussion 12:15 Lunch break 13:30 Tumor board on Gastro-intestinal tumors 5 cases presented by participants and discussed by the panel 16:00 Coffee break SUPPORTIVE THERAPY 16:15 Assessment of patients comorbidity and comprehensive geriatric assessment B. Šeruga, SI 16:45 Treatment and prevention of nausea/vomiting A. Eniu, RO 17:15 Treatment and prevention of hematologic toxicities E. Matos, SI 17:45 Target agents toxicity B. Šeruga, SI 18:15 Fertility preservation B. Šeruga, SI 18:45 Discussion

7 TUESDAY, 1 JULY LUNG CANCER AND MESOTHELIOMA 9:00 Lung cancer pathology and molecular biology I. Kern, SI 9:30 Surgery of lung cancer and mesothelioma T. Štupnik, SI 10:00 Neoadj/Adjuvant chemotherapy therapy 10:30 Coffee break 10:45 Optimal management of N2 disease D. Jovanovic, RS 11:15 Systemic therapy of NSCLC 11:45 Treatment of SCLC D. Jovanovic, RS 12:15 Mesothelioma D. Jovanovic, RS 12:45 Discussion 13:15 Lunch break 14:15 Tumor board on Lung cancer 5 cases presented by participants and discussed by the panel 16:45 Coffee break 17:00- Spotlight lecture: New developments in systemic therapy of germ cell 17:45 tumors J. Beyer, CH 18:00- Learning self- assessment discussion 19:00 R. Herrmann, CH

8 WEDNESDAY, 2 JULY HEAD AND NECK CANCER 9:00 Combined chemoradiotherapy in head and neck cancers P. Strojan, SI 9:30 Systemic therapy B. Zakotnik, SI 10:00 Discussion 10:30 Coffee break GENITO-URINARY CANCERS 10:45 Systemic therapy of bladder cancer B. Šeruga, SI 11:15 Systemic therapy of prostate cancer J. Beyer, CH 11:45 Discussion 12:15 Lunch break SARCOMAS 13:15 Treatment of non-gist soft tissue sarcomas B. Zakotnik, SI 13:45 Update on GIST therapy F. Krasniqi, CH 14:15 Bone sarcomas F. Krasniqi, CH 14:45 Discussion 15:15- Learning self- assessment discussion 16:15 R. Herrmann, CH 16:15 Close Participants departures

9 GENERAL INFORMATION ORGANISING SECRETARIAT Roberta Ventura European School of Oncology (ESO) Via Turati, Milan, Italy rventura@eso.net Tel: ATTENDANCE TO THE MASTERCLASS IS BY APPLICATION ONLY Successful applicants are granted free registration and accommodation APPLICATION DEADLINE: 27 APRIL 2014 Information and application available at: IDEAL MASTERCLASS CANDIDATE Age up to 40 years At least 2-3 years experience mainly in medical oncology or clinical oncology Involvement in scientific activities Fluency in English Priority will be given to candidates practising in Eastern Europe and Balkan Region countries. HOW TO APPLY Application may be carried out online or by filling in the form at (or on request to rventura@eso.net) and providing: Letter describing motivation for attending Supporting letter by the mentor or head of department CV with a list of publications (if the list of publication is not provided, it will be assumed that no articles have been published) Pre-selected participants will be requested to submit an abstract of a clinical case related to one of the topics covered by the programme (breast cancer, gastro-intestinal tumours, lung cancer). CME ACCREDITATION Application for CME recognition will be submitted to the European Society for Medical Oncology (ESMO) for ESMO-MORA accreditation, to the Accreditation Council of Oncology in Europe (ACOE) and to the European Accreditation Council for Continuing Medical Education (EACCME), an institution of the European Union of Medical Specialists (UEMS). EACCME credits are recognised by the American Medical Association towards the Physician s Recognition Award (PRA). Information on the status of the applications can be obtained from the organising secretariat.